“Digital Health – COVID-19 as a Catalyst for Changes in the German/NRW and Japanese Health Care System –Developments in Medical Regulations, Clinical Environments and Business Opportunities”

NRW Japan Fireplace WebTalk

Tokyo22nd May, 202016.00 – 17.50 JST

10 REASONS WHY WE INVITE YOU NORTH-RHINE WESTPHALIA

Global Excellence in Logistics

One of Europe‘sbest Talent Pools

World class R&D and Universities

Leading the Digital Transformation

Great quality of lifein NRW

Industrial heartlandof Germany

Home to worldmarket leaders

Germany‘s No. 1 investment location

Gateway to Europe and Germany

Business in thecenter of Europe

02.01. 03. 04. 05.

10.09.08.07.06.

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NRW / DÜSSELDORF: JAPAN‘S BUSINESS HUB IN THE EU

NRW: No. 1 in Germany

Population 17.9mnGDP 691.5bn EUR

FDI 179.3bn EUR

Japanese Business Hub

Population 14,800Cos./Employ. > 650 / 52.000

Infrastructure KG / Schools3

COVID-19 TIMELINE IN NRW AND GERMANY

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First Covid-19 Case in Germany

January 27

German Government

sets up Corona Crises

Team

Entry Restrictions at German and NRW borders

March 15

German States ordered to

activate Pandemic Plans

February 24

First confirmed Covid-19 Case in NRW

February 25

Closing of Schools, universities and

child care institutions as well

as amusement institutions a.o.bars, museums

16 March

Measures for direct contact

reduction in public space, lock down of

public life

March 22

Easing of measures incl. a.o.

opening of schools

and small businesses

April 20

First confirmed Covid-19 death

in NRW

March 9

Closing of public pools, sauna, gyms

March 17

Corona Reproduction rate drops to

0.7

April 16

Reopening of Parlours, Museums, Exhibitions, Castles etc.

May 4

Reopening of all businesses,

gyms, dancing schools, holiday

houses etc.

May 11

Permission for

performing no-contact

sports

May 7

Permission for

performing contact

sports, public indoor pools and cinemas

May 30

NRW: 20 OF GERMANY‘S TOP 50 COMPANIES (BY SALES)

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NRW州の魅⼒あるビジネス環境と⽇系企業の動き｜株式会社NRWジャパン ゲオルグ・ロエル｜2019年7⽉25⽇

HIDDEN CHAMPIONS BASED IN NRW (SELECTION)

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NRW Japan K.K.

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TEAM MISSION

Create Success Stories in NRW• Business Promotion & Consulting

for Japanese Companies• Industry Research for Market Entry

and FDI in Europe/Germany • Support for Establishment of Rep.

Office, Subsidiary, R&D Ctr., etc.• Introduction of Universities, R&D

Centers, Govt. and Stakeholders • Hosting NRW.INVEST Seminars,

„Fireplace Talks“ and other Events• Participation in Trade Fairs, Science

Events and Industrial Exhibitions• Special Focus on Innovative Techno-

logies, Startups and Growth Markets8

Japan

What does the Japanese economy look for?

CurrentIssues

General Issues

NRW

Markets

Research Areas and Research Institutions

Industries and Competences

Technologies and Companies

Products

Markets

Research Areas and Research Institutions

Industries and Competences

Technologies and Companies

ProductsPush

Pull

Identify needs

Offer solutions

Fit?

Fit!

What does the economy of North Rhine-Westphalia offer?

MARKETS – TECHNOLOGIES – INNOVATION

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CONNECTING ALL STAKEHOLDERS

Distributors

Banks

Universities

Accountants

Trade Fairs

Japanese Client

NRW Japan K.K.

NRW.Invest GmbH

Business Associations

State Government

Research Institutions

Regional Agencies

Law Firms

Hospitals

Notified Bodies

Companies Real Estate Agents HR Consultants

Federal Government Innovation Hubs/Startups Media

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NRW INNOVATION STRATEGY & CLUSTERS

- Focus on industries dealing with future global challenges

- Strengthening innovation culture- Support internationalization

Lead-markets Strategy

Production Technology New Materials

Mobility & Logistics IT

Energy & Sustainability Media

Health & Life Science

14 State Clusters

BusinessPoliticsResearch

Regional Clusters

NRW UNIVERSITIES & RESEARCH INSTITUTIONS AS PARTNERS

Research and Innovation Networks

• 70 Universities- Open Innovation & Transfer

Centers- Ca. 768,000 students (26.9%)

• 50+ R&D Institutions collaboratewith business & universities- Leading Fraunhofer Institutes,

Leibniz & Max-Planck Institutes• 60 Technology Centers and

30 Technology-Transfer Institutions

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START-UPS ACTIVITIES IN GERMANY & NRW

- In 2018, 19.0% of German startupsoriginated in NRW: No.1 in Germany

- 24.9% of all German AI startupsoriginate in NRW

- 73.4% of startups are focussed onB2B (German Ø is 67.7%)

>295 Start-Ups

>733 Founders

NRW: Active Startup Culture Focus on B2B Startups

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344 Hospitals in NRW, 18% of all German Hospitals118,506 Hospital Beds, 23% of all German Hospital Beds

Highest Hospital Density within Germany

265,103 People employed in Hospitals22% of all German Hospital Employees

1.4 Mio employees in the Medical and Health Sector

46,177,760 annual cases/patients in NRW23% of all German cases/patients

7 University Hospitals (AC, BN, BO, D, E, K, MS)

Turnover of annually 75 Bn. Euros, 12% of NRW’s GDP

Medical and Health Care Market in NRW

Source: https://www.medizin.nrw

n 6 healthcare regions within NRWAachen： Medical engineeringCologne/Bonn： Medical care for the

elderlyRuhr Metropolis： Clinical businessMünsterland： Preventive medicineOstwestfalen-Lippe/Bielefeld: Medical service networkSouthern Westphalia: Medical engineering

n Close partnership with R&DIndustry-university cooperation with universities, research institutes and corporations in NRW

n Health Campus NRW BochumDomestic and international networking and cooperation

6 healthcare regions within NRW

Source: CGW.NRW(31)

NRW Health Care Sector

Partners: Health Clusters enable Commercial Implementation Connecting all relevant Stakeholders in Health Care supply

Partners: NRW - Hub for healthcare and medical device industry

CYBERDYNE – SUCCESSFUL JAPANESE STARTUP IN NRW

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• Cooperation between QD Laser Inc. and the Medical Faculty of the University of Duisburg-Essen in Essen(Prof. Dr. Sauerwein/Prof. Dr. Eckstein)

• QD Laser Germany GmbH, founded in Essen to conduct clinical tests with the "LEW® Laser Eyewear" vision aid developed jointly with Univ. of Tokyo.

• In Japan the Retissa ® Laser Eyewear which enable patients with severe visual impairment to see is on the market since early 2020.

QD LASER INC. – SUCCESSFUL JAPANESE STARTUP IN NRW

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More than 128,000 sqm of exhibition space

Over 750 exhibitors from 40 countries with 197 exhibitors from Japan

In 2019, 121,000 trade visitors and more than 5,500 exhibitors attended COMPAMED/MEDICA

Partners: NRW Health Trade Fairs Lead to Business

Düsseldorf

Business Model Development

Evaluation/Studies

Development of Disease Management Programmes

Program Operation

The DITG develops innovative, digital patient management programswith evidence-based benefits. DITG supports its customers in theprocess, from developing a concept and evaluating it in the context ofstudies to implementing entire business models on the market.The basic strategy is composed of three core fields:

• Providing information about the illness, because education is vital to long-term improvement.

• Motivation to change one’s own behavior and overcome old habits.

• Adjusting the therapy and medication with the involvement of the patient’s doctor.

Partners: Curalia & TeLiPro (now part of Helios Hospitals Group)Deutsches Institut für Telemedizin und Gesundheitsförderung

DIGITAL HEALTH GLOBAL – 150 STARTUPS (2019)

DIGITAL HEALTH IN JAPAN – KEY PLAYERS (SELECTION)

DIGITAL HEALTH IN GERMANY – KEY PLAYERS (SELECTION)

PRESENTATIONDIERKS+COMPANY

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Dierks+CompanyProf. Dr. med. Dr. iur. Christian DierksLawyer, Managing Partner

• Specialist lawyer for social and medical law• General Practitioner• Professor for health services research• Active as a lawyer since 1990

• Co-founded Dierks+Company, an innovation consultancy for healthcare and life sciences in 2018

• Expertise: Innovation management and market entry

• Teaches digital health at universities in Germany and Italy

• Member of the Legal Committee of the German Federal Association of Pharmaceutical Industries (BPI)

• Chair of the Legal Working Group of the European Confederation of Pharmaceutical Entrepreneurs (EUCOPE)

SPEAKER‘S PROFILE

PRESENTATIONMEDMAIN INC.

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Medmain Inc.Mr. Osamu IizukaCEO

• Developed software in Machine Learning, Deep Learning and Web during his studies at Kyushu University School of Medicine

• Work experience as a web-engineer in a startup

• Placed first at a pitch competition in Silicon Valley

• Winner of the Kyushu University President’s Award

• Selected as “Forbes 30 Under 30 Asia 2020” by Forbes magazine

• Founded Medmain Inc. in 2018

SPEAKER‘S PROFILE

• Worked at Niigata University, Yale University and theNational Cancer Center as a pathology researcher,pathologist and academic teacher

• Ph.D. in Pathology since 2013

• Joined Medmain Inc. in 2018

• Research interest: Molecular pathology, particularly related to carcinogenesis and pathological AI

• Aim: Creating a new technology that can provide an objective diagnosis in the field of clinical pathology

• Recent success in the development of a practical diagnostic assistant AI model for gastric and colonic epithelial tumors

SPEAKER‘S PROFILE

Medmain Inc.Dr. Masayuki TsunekiDirector of the Board

• Graduate from Boston University (International Relations, Public Health)

• Placed first in the annual Boston University Entrepreneurship Startup Challenge

• Internship experience at the World Health Organization (WHO) in Geneva, Switzerland

• Former employee at an HCM software company in Southern California

• Joined Medmain Inc. in May 2019

SPEAKER‘S PROFILE

Medmain Inc.Ms. Leona ShinkaiMarketing Representative

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PRESENTATIONPLIMES INC.

PLIMES Inc.Dr. Eng. Kenji Suzuki President & Co-Founder

• B.S. in Physics, M.E. and Dr. Eng. in Pure and Applied Physics from Waseda University

• Since 2016: Professor at the University of Tsukuba, Faculty of Engineering, Information and Systems

• Principal Investigator of the Artificial Intelligence Laboratory, University of Tsukuba

• Primary research interests: AI, Cybernics, wearable robotics and devices, affective computing, social robotics, assistive robotics

• Launched startup company PLIMES Inc. in 2018• Product: AI/IoH-based device for measuring

swallowing activities (pneumonia prevention)

• Elected administrative commitee member of the IEEE Robotics and Automation Society

SPEAKER‘S PROFILE

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NRW JAPAN K.K. FIREPLACE TALKOPEN DISCUSSION

CONTACTS

Georg K. LöerRepresentative Presidentand Director

Ryuji SugizakiSenior ManagerBusiness Development and Research

Naoko YagihashiMarketing Manager

NRW JAPAN K.K.Economic Development Agency of the German State of North Rhine Westphalia (NRW)

〒 102-00944-1 Kioicho, Chiyoda-ku Tokyo JapanNew Otani Garden Court 7F

Haruaki KusukiManagerBusiness Development and Research

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+81 3 5210 2300

contact@nrw.co.jp

www.nrw.co.jp

@NRWJapan

@NRWJapan

@NRW.invest-japan