Nano-Tera 2015: Entrepreneurship Presentations

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Transcript of Nano-Tera 2015: Entrepreneurship Presentations

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Therapeu*c  Drug  Monitoring  (TDM)  

Today:  

[1]  Edurant  (Rilpivirine)  prescribing  informa*on    

???

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Today:  

[1]  Edurant  (Rilpivirine)  prescribing  informa*on    

0 6 1 2 1 8 2 4 3 0 3 6

1 0

1 0 0

1 0 0 0

T im e a f te r d o s e [H o u rs ]

Rilp

ivir

ine

Co

nc

en

tra

tio

ns

(ng

/m

L)

Target  Cmin=44ng/mL  

Cmin  <  44ng/mL  for  40%  of  popula;on  !  

TDM  of  Rilpivirine  (an*retroviral    drug)      

35  000  000  HIV+  6300  new  infec;on/day  

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Today:   Tomorrow:  

Therapeu*c  Drug  Monitoring  (TDM)  

ü  automated    ü  personalized    

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Population-based percentiles

Individual concentration vs time profile dosing schedule suggestion

ü  Predic*on  engine  (Bayesian  approach)    ü  Ergonomic  soHware  

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DBMS, remote data collection

Easy to integrate (Health Level 7 interface)

EzeCHiel light

Clinical interpretation (TDM) Drug developement

Clinical trials

Aggregation of data for the research

Ø  Precision    Ø  Predic;on  modeling  Ø  Time  Ø  Interoperability  Ø  Privacy  &  Security  Ø  U;lity  Ø  User-­‐friendly    

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Team  

Dr.  Séverine  Pe;tprez,  Drug  models  development  

Alev;na  Dubovitskaya,    Data  mining,  Interoperability  

Dr.  Manel  Aouri,    Clinical  evalua8on  

Prof.  T.  Buclin,  MD   Dr.  N. Widmer   Prof.  C. Csajka  

A.  Chaouch    

Dr.  M.  Guidi  

Advisory  Board:  

Dr.  P.  André  

Prof.  Y.Thoma  

Y.  Su]er    R.  Hooper  

Prof.  M.  Schumacher  

Division  of  Clinical  Pharmacology,  CHUV  Development  of  drug  models,  clinical  evalua8on  

REDS  HEIG-­‐VD,  HES-­‐SO  VS  So;ware  development,  Interoperability  

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Ac*on  Plan    

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Ac*on  Plan  

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1/09 Nano-Tera Meeting, Bern| 04 May, 2015

We sell Onsite H2 production system

which is cost effective, cleaner & greener, for fertilizer

and chemical industries

Ready to Launch

Solar Fuel, the smarter way.

SoHHytec

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2/09 Nano-Tera Meeting, Bern| 04 May, 2015

Refineries 20%

Ammonia 53%

Other 20%

Methanol 7%

Our Customer

H2 Usage

Fertilizer and Chemical industries  

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3/09 Nano-Tera Meeting, Bern| 04 May, 2015

Problem worth solving:

On site cost effective H2 production using smart combination of concentrated solar energy during day and cheap grid electricity during night using our Integrated PEC device

Lack of cost effective onsite H2 production. 95% of current world H2 production comes from off-site steam reforming of conventional fossil fuels which is

Our Solution:

Not clean & non-renewable

Costly due to specialized transportation

Downscaling the size becomes extremely expensive

Faster degradation of the system

Cleaner & Greener

Highly scalable in size (up/down)

Onsite hence no costly expenses for transportation

Longer and durable life span

Our Opportunity

Lack of cost effective onsite H2

production

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4/09 Nano-Tera Meeting, Bern| 04 May, 2015

Night Operation

Compressor

Storage

Concentrator

H2 O2

H2O

Cheap Grid Electricity

During night

CUSTOMER

PV+ELECTROLYZER

Our Product

Integrated PEC

Day Operation

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5/09 Nano-Tera Meeting, Bern| 04 May, 2015

Case Operation Type Price

1 Our System 1.69 $/Kg Great combination of sunlight during day and cheap electricity during night

2 Just electrolysis using electricity (Day + Night)

2.21 $/Kg

Even just day electricity price during the lifespan makes it expensive option

3 Steam reforming requiring transportation

2 $/Kg Transportation alone increase price of hydrogen by 1$/kg* of H2 *Hydrogen   Sta.on   Compression,   Storage,   and  Dispensing  Technical  Status  and  Costs  ,G.  Parks,  R.   Boyd,   J.   Cornish,   and   R.   Remick   ,   NREL  Independent  Peer  Review  Report  

1   2   3  

1.69 $

2.21 $ 2 $

Business Potential

Our H2 Production cost (without CSD) including 15% ROI  

1.69 $/Kg  

For 50m by 50m system producing 234 Kg H2/ day  Exemplary case

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6/09 Nano-Tera Meeting, Bern| 04 May, 2015

How we make Profit

Strategy: 15% ROI plus yearly charges equal to 50% of customer’s saving potential for next 15 years  

day 1 year 1-10 year 10-15

54k $

132k $ 136k $

For the installation of the size of 50m by 50m with 360k $ investment  

0

2

1 3 5 7 9 11 13 15 Years

Customer’s Saving potential   Our profits  

$/Kg

of H

2

Our  system  

Distributed  steam  reforming  

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7/09 Nano-Tera Meeting, Bern| 04 May, 2015

Meet our Team

Saurabh Tembhurne CEO and co-founder Doctoral Ass istant in ENERGY Laboratory of Renewable Energy Sc ience and Engineering (LRESE) EPFL, Lausanne

Meng Lin CTO and co-founder Doctoral Ass i s tant in ENERGY Laboratory of Renewable Energy Sc ience and Engineering (LRESE) EPFL, Lausanne

Prof. Sophia Haussener Scientific Advisor Assistant Professor Laboratory of Renewable Energy Sc ience and Engineering (LRESE) EPFL, Lausanne

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8/09 Nano-Tera Meeting, Bern| 04 May, 2015

Gives as Great Opportunity to showcase and demonstrate our product as well as would be a brilliant chance to make new connections and attract tentative investors

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9/09 Nano-Tera Meeting, Bern| 04 May, 2015

THANK YOU

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Ø Wearable  sensing  devices  will  represent  $47.4B  market*  in  2019    

Ø Wearable  electronics  should  be  conformal,  light  weight  and  unno6ceable    

Ø  However  current  electronic  solu@ons  are  rigid,  planar  and  bulky.      

*  Source  :Onworld  Wearable  Technologies  Consumer  Survey  

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Ø We  are  a  wannabe  EPFL  Spin-­‐off  -­‐  Prof.  S.  P.  Lacour:      Laboratory  for  soM  bioelectronics  interfaces  

 Ø  Target  Market:  Electronic  companies    

Ø We  provide  B2B  technological  solu6ons  to  help  industrial  partners  implement  systems  that  can  conform  to  the  human  body  

   Ø  Robustness,  Cost  effec6veness  Design  flexibility  

Ø  Patent  applica@on  ongoing,  backed  by  EPFL  TTO  

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SolSticE

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SolSticE SolSticE Solar Sticker for Energy

Highest Efficiency MaterialsFlexible

Adhesive

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SolSticE SolSticE Applications

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SolSticE SolSticE Benchmark

Flexibility

Com

fort

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SolSticE SolSticE Planar VS Nanowire

p-doped

n-dopedintrinsic

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10 µm

SolSticE SolSticE Achievements

Status

• First prototype on Si. • Peeling procedure

developed. • The Silicon wafer can be

reused. • The technique is scalable

independently on the wafer size.

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SolSticE SolSticE Open Challenges

Status

• Realization of high conductivity and flexible contacts.

• Iterative optimization of the design.

• Scale up.

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Princess Astronaut Wizard

SolSticE SolSticE The Team

Jelena Vukajlovic-Plestina

Dmitry Mikulik

Federico Matteini

CTO CEOCOO

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November 2–4, 2015, MIT Media Lab, Cambridge, MA

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SolSticE SolSticE