Lapsus Cardio v3

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    Nurfitrianti (c11109300)

    Supervisor:dr. Muzakkir Amir, Sp.JP, FIHA, FICA

    PULMONARY EMBOLISM + CHF NYHA IV ecHHD + PH SEVERE

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    PATIENT IDENTITY

    Name : Ms.N

    Gender : Female

    Age : 53 years oldAddress : Enrekang

    Registration number : 615504

    Date of admission : 26th July 2013

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    HISTORY TAKING Chief complain : Unconsciousness Present illness history:

    Patient was unconscious 2 hours before admitted toWahidin Sudirohusodo Hospital. Unconsciousness wasoccur suddenly, and accompanied with shortness of

    breath, bluish color on lips and extremities. History ofadmitted in PCC Hospital with swelling on lowerextremities, shortness of breath, and cough with whitesputum, and diagnosed with Congestive Heart Failure. 2hours before, patient suddenly unconscious, withshortness of breath, and bluish color on lips and lower

    extremities. And referred to Wahidin SudirohusodoHospital for further treatment. According to family, patientslept with 2-3 pillows during sleeping for 6 months andbreathlessness in walking far distance. Since than patientdo little activity and only eat and sleep in her house. Nochest pain, palpitation, fever, nausea, and vomiting.

    Urination and defecation was normal

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    Previous illness history:

    - History of admitted in PCC Hospital on July 26th

    2013 with swelling lower extremities and shortnessof breath. Diagnosed as CHF

    - History of hypertension for 7 years, with highestblood pressure of systolic 240 mmHg. With irregulartreatment.

    - History of heart disease for long time.

    - No history of Diabetes Mellitus

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    Physical Examination General Status :

    Moderate-illness/obese/unconscious

    Vital Sign :

    Blood Pressure : 140/90 mmHg

    Pulse : 84 bpm, regular

    Respiratory rate : 29 tpm

    Body temperature : 36,5 C BMI : 32,4kg/m2

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    Head Examination

    Eyes : anemic -/-, icterus -/- Lip : cyanosis (+) Neck : JVP R +1 cmH2O,

    lymphadenopathy (-)

    Chest Examination

    Inspection : symmetric R=L, normochest Palpation : mass (-), tenderness (-)

    Percussion : sonor Auscultation :

    breath sound : vesicularadditional sound : ronchi -/-

    wheezing -/-

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    Cardiac Examination

    Inspection : Ictus cordis wasntvisible

    Palpation : Ictus cordis wasntpalpable

    Percussion :- Right border : right parasternalis line- Left border : 1 finger to the lateral

    of left midclavicular line

    Auscultation : Regular of I/II heart sound

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    Abdominal Examination

    - Inspection : flat and following breath movement- Auscultation : peristaltic sound (+) , normal- Palpation : liver and spleen unpalpable- Percussion : tympani, ascites (-)

    Extremities- Edema : Pretibial +/+ and dorsum pedis

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    LABORATORIUM FINDINGSTest Result Normal value

    WBC 6,35 x 106 4,0-10,0 x 103

    HGB 13,9 13,0-17,0 g/dl

    HCT 47 40,0-54,0 %

    PLT 218 150-500 x 103

    RBC 6,29 4-6 x 106

    Ureum 23 10-50 md/dL

    Creatinin 1,1

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    LABORATORIUM FINDINGSTest Result Normal value

    Na 123 136-145 mmol

    K 3,2 3,5-5,1 mmol

    Cl 81 97-111 mmol

    Albumin 3,4 3,5-5,5 g/dLPT 16,3 control 11,7 10-14 second

    APTT 95,6 control 27,0 22-30 second

    GDS 294 140 200 mg/dL

    CK 41 L(

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    Analysis blood gases

    Test Result Normal value

    pH 7,32 7,35-7,45

    pCO2 74,8 mmHg

    SO2 91,6

    PO2 51,5 80-100 mmHg

    HCO3 30,0 22-26

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    ECG (29/07/13)

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    ECG interpretation- Rhythm : Sinus rhythm- HR/QRS rate : 75 bpm, rreguler

    - Axis : Right axis deviation

    - P wave : 0,12 s- PR interval : 0,2 s

    - QRS complex : 0,08 s, V5 R/S

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    Conclusion:

    Sinus rhythm, HR 75 bpm, right axis deviation,biatrial hypertrophy, right ventricular hypertrophy,inferior wall ischemic and injury.

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    CHEST X-RAY

    Cardiomegaly with pulmonary edema

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    DIAGNOSISSuspect pulmonary embolismCHF NYHA IV ec HHD

    PH severe

    Elektrolyte imbalanceHyperglycemia

    CAP

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    INITIAL MANAGEMENT O2 10 L/minute (via NRM) IVFD NaCl 0,9% 500 cc/24 jam Heart diet Heparin 5000 IU bolus/IV Heparin 1000 IU/jam/IVAspirin (Aspilet) 1x80 mg Clopidogrel (Plavix) 1x75 mg

    Furosemide inj 2 A/12jm/IV Dobutamin 5 mikro/SP Tapp off Ceftriaxone inj 2 gr/24 jam/IV (Skin test)

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    PULMONARY EMBOLISM

    Discussion

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    DEFENITION

    Pulmonary embolism is a clinically significantobstruction of part or all of the pulmanaryvascular tree, usually caused by thrombus from a

    distant site.

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    ETIOLOGY

    The causes for pulmonary embolism are multifactorialand are not readily apparent in many cases. Thecauses described in the literature include thefollowing:

    Venous stasis Hypercoagulable states

    Immobilization

    Surgery and trauma

    Pregnancy

    Oral contraceptives and estrogen replacement

    Malignancy

    Hereditary factors Acute medical illness

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    RISK

    FACTORS

    MAJOR Surgery Major abdominal/pelvic surgeryOrthopaedic surgery (especiallylower limb)Post-operative intensive care

    Obstetrics Late pregnancy (higher incidencewith multiple births)Caesarean sectionPre-eclampsia

    Malignancy Pelvic/abdominalMetastatic/advanced

    Lower limb problems Fracture, varicose veins

    Reduced mobility HospitalizationInstitutional care

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    MINOR Cardiovascular Congenital heart diseaseCongestive cardiac failureHypertensionCentral venous access

    Superficial venousthrombosis

    Oestrogens Oral contraceptive pill(especially third-generationhigher oestrogencontaining)Hormone replacementtherapy

    Miscellaneous Occult malignancyNeurological disability

    Thrombotic disordersObesityInflammatory boweldiseaseNephrotic syndromeDialysis

    Myeloprofilerativedisorders

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    Pathophysiology

    Decrease in blood flow below a certain criticallevel.

    Increase in coagulability of blood. Damage of the vessel wall.

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    Pathophysiology

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    Symptoms and signs

    - Symptoms: - Signs:

    Shock Cyanosis

    Dyspneu TachypneuPleuritic pain Rales

    Anterior chest pain Tachycardia

    Cough S4

    Hemoptysis Accentuated P2

    Asymptomatic

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    Clinical probability scoringsystem

    - Raised respiratory rate- Haemoptysis

    - Pleuritic chest pain

    Plus 2 other factors:1. Absence of another reasonable clinicalexplanation

    2. Presence of a major risk factor

    a) plus 1 and 2: HIGH pre-test clinical probabilityb) plus 1 or 2: INTERMEDIATE pre-test clinical

    probability

    c) alone: LOW pre-test clinical probability.

    W ll C it i

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    Wells Criteria

    Clinical Signs and Symptoms of DVT?

    (Calf tenderness, swelling >3cm, errythema, pittingedema affected leg only)

    +3

    PE Is #1 Diagnosis, or Equally Likely +3

    Heart Rate > 100 +1.5

    Immobilization at least 3 days, or Surgery in thePrevious 4 weeks

    +1.5

    Previous, objectively diagnosed PE or DVT? +1.5

    Hemoptysis +1

    Malignancy w/ Rx within 6 mo, or palliative? +1

    >6: High Risk

    2 to 6: Moderate Risk

    2 or less: LowAdapted with permission from Wells PS, Anderson DR, Rodger M, Ginsberg JS, Kearon C, Gent M, et al. Derivation of a simple

    clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED d-dimer.Thromb Haemost 2000;83:416-20.

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    Diagnostic testArterial blood gases Cardiac Enzymes: Troponin D-dimer EKG CXR Ultrasound Echocardiography

    Angiography

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    Management Respiratory Support: Oxygen, intubationAnticoagulation

    Thrombolysis

    Embolectomy

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    THANK YOU