Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life...

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1 Colja Laane Board member Regiegroep Life Sciences & Health Director Netherlands Genomics Initiative

Transcript of Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life...

Page 1: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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Colja Laane Board member Regiegroep Life Sciences & Health

Director Netherlands Genomics Initiative

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Life Sciences & Health in The Netherlands

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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written

• In 2011 the ‘Regiegroep LSH’ was formed

• In 2012 the ‘Innovation contract’ has been signed

• In 2012 ‘LSH Plaza’ became operational

• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships

Topsector LSH: were do we stand ?

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Page 5: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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The topsector's vision links health and wealth for society and economy

LIFE SCIENCES

& HEALTH

Society Economy

Hea

lth

W

ealt

h

QUALITY OF LIFE

PRODUCTIVITY

AFFORDABILITY BUSINESS

The topsector envisions a thriving Dutch Life Sciences & Health sector that develops innovative health solutions based on scientific excellence that:

> improve QUALITY OF LIFE of patients

> support the AFFORDABILITY of healthcare

> increase PRODUCTIVITY within and beyond healthcare

> create BUSINESS VALUE in the Netherlands

Source: topsectorplan; cahier no. IV

Vision

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Ambition: 3 objectives, which together contribute to affordable, high-quality healthcare

PREVENTION CURE CARE

1. Maintain health, prevent healthcare

2. Maximize effect, minimize trauma

3. Manage disease extramurally

Page 7: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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The topsector plan identified 7 critical success factors for a strong Life Sciences & Health sector

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IDEA GENERATION Increase the number of promising ideas

DEVELOPMENT Accelerate the development process and heighten the chance of success

APPLICATION Accelerate and broaden effective application (nationally and internationally)

Demanding Dutch market with a portal into Europe and the rest of the World

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Optimized legal and regulatory landscape 2

Sufficient well educated, entrepreneurial people 3

Good accessibility to the right capital 4

Shared public-private innovation infrastructure 6

The Netherlands as one self-organized Life Sciences & Health sector 7

Strong, accessible (fundamental) knowledge base 5

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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written

In 2011 the ‘Regiegroep LSH’ was formed

• In 2012 the ‘Innovation contract’ has been signed

• In 2012 ‘LSH Plaza’ became operational

• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships

Topsector LSH: were do we stand ?

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Page 9: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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Regiegroep Life Sciences & Health

A 'Regiegroep' was installed to bundle forces in the sector and to stimulate, facilitate and integrate LSH activities

A core team has been given the mandate to act on behalf of the ‘Regiegroep’: Large industry: Rob van Leen SME’s: Hans Schikan, Len de Jong Academia: Huib Pols Government: Paul Huijts Secretariat: Frans van den Boom Petra van Baak (EZ) URL: www.regiegroepLSH.nl

Hans Schikan

Martin Paul

Huib Pols

Roger van Boxtel

Geri Bonhof EDUCATION

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Important deliverable: Regiegroep members have started ‘own’ instruments for the LSH sector

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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written

In 2011 the ‘Regiegroep LSH’ was formed

In 2012 the ‘Innovation contract’ has been signed

• In 2012 ‘LSH Plaza’ became operational

• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships

Topsector LSH: were do we stand after?

1

Page 12: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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‘Innovation contract’: 10 roadmaps connect and structure the sector based on technology or applications area’s

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PREVENT DIAGNOSE CURE CARE

Keep people healthy as long as possible

Diagnose early, before complica-tions arise

Individua-lize treatment for best results

Treat with minimal side-effects

Replace or repair body functions

Move from care to cure (unmet needs)

Reduce symptoms, slow down disease

Enable chronic patients to stay at home

Molecular diagnostics

Imaging & image guided therapies

Pharmacotherapy

One Health

Regenerative medicine

Global health (previously neglected diseases)

Health technology assessment & quality of life

Specialized nutrition, health & disease

Enabling technologies & infrastructure

RO

AD

MA

PS

Self-management, home care & ICT

Many x-topsector initiatives

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In 2011the topsector plan ‘voor een gezond en welvarend Nederland’ was written

In 2011 the ‘Regiegroep LSH’ was formed

In 2012 the ‘Innovation contract’ has been signed

In 2012 ‘LSH Plaza’ became operational

• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships

Topsector LSH: were do we stand?

1

Page 14: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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LSH Plaza builds upon existing expertise by bringing together stakeholders in the LSH sector

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Through its structural core, the LSH Plaza performs basic stimulus, facilitation and integration activities

according to the ambition, securing the Plaza's operation and continuation

STRUCTURAL CORE

NETWORK OF ENABLERS

Through its network of enablers, the LSH Plaza mobilizes enabling organizations to perform extended stimulus, facilitation and integration activities, and shape the

public-private innovation infrastructure

The network of enablers will be in continuous motion, as existing enablers may end and new enablers may start

The network of enablers contains different organizations with different roles and different

relations to the Plaza and its structural core

GOVERNMENT

PRIVATE

NETWORK OF ENABLERS

LSH PLAZA

PUBLIC

STRUCTURAL CORE

TTIs Industry

organizations

Health foundations

NGI

DTL/e-science center

LS@Work

Tech transfer offices

Roadmaps/ community

leaders

Biobanks

e.g. SMEs, large industry, health insurers, health foundations, financiers, etc.

e.g. universities, UMCs, KNAW/NWO institutes, TNO, etc.

NWO/ ZonMw/

STW

Syntens

Regions/ regional

initiatives

TNO

Science parks, shared

infrastructure

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LSH Plaza has the mission to support public-private partnership in Life Sciences & Health

Mission

LSH Plaza

Basic knowledge Translation Delivery

SCIENCE PUSH MARKET PULL

PPP

Partners Experience

Investments

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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written

In 2011 the ‘Regiegroep LSH’ was formed

In 2012 the ‘Innovation contract’ has been signed

In 2012 ‘LSH Plaza’ became operational

From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships

Topsector LSH: were do we stand?

1

Page 17: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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Recent calls for proposals aimed at building partnerships

>2012 IMDI (ZonMW) 2013 LSH Impuls > 2013 LSH Match

> 2013 MIT > 2012 Research Hotels 2014 2Treat (ZonMW)

2014 Memorable (ZonMW)

Building on PPPs: • NGI • Topinstitute Pharma • CTMM • BMM Total: € 400 M/y

Page 18: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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• Horizon 2020 (~70 billion/7 yrs; ~12% for health) as

Common Strategic Framework

• Structural funds (EFRO, ESF)

• European Innovation Partnerships (EIP, public-private)

Europe 2020: meeting the grand challenges

Page 19: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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The EU agenda has a clear connect with the LSH and other topsectors: for example in Active & Healthy Ageing

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Prevention,

Awareness,

Screening, Early

diagnosis

Cure & Care Active Ageing,

Independent

living

Creative

industry

Life

Science &

Health

Hightech

Systems &

Materials

Agro/food

Molecular diagnostics,

Imaging & image guided

interventions

Regenerative medicine

Health Economics

--------------- Media & ICT, Serious gaming, Smart Design ----------------

Pharmacology and

pharmacotherapy,

Regenerative medicine

ICT & clinical decision

support,

Hospital-to-home care

Imaging & image guided

interventions

ICT & clinical decision

support,

Self management

Hospital-to-home care

Cardiovascular health,

Gastro intestinal health,

Food and cognition

Weight management,,

Food and cognition,

Sensory & liking

Weight management,

Food, ageing & cognition

Medical imaging,

Patient specific modelling,

New modalities for diagnostics,

Image-Guided interventions,

Neurostimulation,

Micro- and nanotechnology,

Minimal invasive techniques,

Neurostimulation,

Micro- and nanotechnology,

Biomaterials

Rehabilitation techniques

Rehabilitation techniques

Home and community care

Mechatronics & robotics

Home and nomadic monitoring,

EIP AHA pillars

Topsectors

Connect with the

EIP-AHA constituents:

- Joint programming:

ERANET’s, JPI’s,

Art 185

- Joint infrastructures:

ESFRI’s

EIP- AHA pillars

Du

tch

top

sect

ors

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LSH hot spots

Gelderland and Overijssel: Health Valley, and Twente

• Focus on: Cognitive neuro-sciences, molecular diagnostic, Nanotechnology, technical medical science, care and cure robotica, eHealth

• Important players: NXP Synthon, TNO, Siemens, Astellas, TU Twente, RUN, UMC St Radboud

Zuid-Limburg: Brainport

• Focus on: CV-diseases, metabolic aspects of chronical diseases, public health & primary care, mental healthcare and neuro-sciences. Medical devices

• Important players: DSM, Chemelot, UMC Health Campus,

Noord-Nederland: HANNN

• Focus on: Healthy Ageing • Important players: PRA International, RUG, UMCG,

Hanzehogeschool, Zernike Science Park, ERIBA (and collaboration with Wageningen)

Amsterdam Biomed Cluster

• Focus on: Oncology, cognitive neuro-sciences and neuroimaging, cardiovascular, infectious diseases

• Important players: AMT, VU, VUMC, UvA, AMC, NIN, NKI

Noord-Brabant: Brainport

• Focus on: Medical technology, farmacy, veterinary health and feed

• Important players: Philips Healthcare, MSD/ Organon, MSD/Intervet, GE Healthcare, TU Eindhoven, Amgen

Utrecht and Wageningen: Utrecht Life Sciences & Immuno Valley

• Focus on: Public health, oncology, 'regenerative medicine', stamcells, veterinary diseases, functional foods

• Important players: Genmab, GSK, Danone, UU, UMC Utrecht, RIVM, WuR, TNO

Zuid-Holland: Medical Delta

• Focus on: (Bio)farma, clinical research, 'imaging and image guided medicine' en 'targeted molecular technology'

• Important players: Crucell, Galapagos, Prosensa, Octoplus, J&J/Janssen Biologics, University Leiden, LUMC, TU Delft, Erasmus Medical Centre,

Page 21: Topsectorplan Life Sciences & Health · 2014-06-20 · "A 4 – 20100701 –! 4 Regiegroep Life Sciences & Health In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’

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Future steps

• Build and intensify relations with research funders

• Develop and implement a shared agenda (e.g. Nederland in Zicht)

• Invest in building EU LSH consortia

• Develop cross over initiatives with other topsectors

• Develop consortia who take ownership of roadmaps building up

already existing strenghts and networks