Swe on breast cancer in dense breast with considerations on tnm staging

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Antonio Pio Masciotra Campobasso Molise Italy Email [email protected] Website www.masciotra.net YouTube Channel https://www.youtube.com/channel/UCgCj21nKGAhR997Ia3-QegQ Breast cancer in dense breast as seen at Shear Waves Elastography with discussion about the ‘T’ measurement in TNM staging

description

This case shows how dense breast can hinder cancer at mammography and the important role of US and SWE elastography in situation like this. SWE could be the most reliable tool for the measurement of the 'T' parameter of TNM staging of breast cancer, especially if performed with 3D probe.

Transcript of Swe on breast cancer in dense breast with considerations on tnm staging

Page 1: Swe on breast cancer in dense breast with considerations on tnm staging

Antonio Pio MasciotraCampobasso – Molise – Italy

Email

[email protected]

Website

www.masciotra.net

YouTube Channel

https://www.youtube.com/channel/UCgCj21nKGAhR997Ia3-QegQ

Breast cancer in dense breast as seenat Shear Waves Elastography

with discussion about the ‘T’ measurement in TNM staging

Page 2: Swe on breast cancer in dense breast with considerations on tnm staging

Woman 48 years old feeling a little painin upper quadrants of her right breast. Only mammography performed at the

first exam.

9 months later she feels a nodulebetween the upper quadrants of the

same breast.

27/08/2013

12/05/2014

Page 3: Swe on breast cancer in dense breast with considerations on tnm staging

27/08/2013 12/05/2014 27/08/2013 12/05/2014

Only right breast images in comparison are showed with closeup details.Very dense breast far to offerwell valuable signs.

Maybe the only differencesperceivable are in retromammaryfat area that in the second examseems to host ‘something new’at least in CC view (arrows).

Then US exam was performedshowed in next slides.

Page 4: Swe on breast cancer in dense breast with considerations on tnm staging

Woman 48 years old

Page 5: Swe on breast cancer in dense breast with considerations on tnm staging

Woman 48 years old

Feature (kPa) Nodule

Mean stiffness 86-118

Maximum stiffness 135-299

Minimum stiffness 0,1-95

Standard Deviation 9-64

Hypoechoic area 0,42 cm²

Stiffest area 1,17 cm²

The tumor area tracedaccording echogenicity is far smaller than the area traced

according the stiffness

Page 6: Swe on breast cancer in dense breast with considerations on tnm staging

Woman 48 years old

Feature Echogenicitybased data

Stiffnessbased data

Perimeter 5,42 cm 6,63 cm

Area 1,52 cm² 2,45 cm²

Diameter 1 1,48 cm 2,19

Diameter 2 1,45 cm 1,88

The tumor area traced according echogenicity is large smaller than the area traced according the stiffness.

Page 7: Swe on breast cancer in dense breast with considerations on tnm staging

Woman 48 years oldPlane Feature Echogenicitybased data

Stiffnessbased data

Difference(%)

CoronalPerimeter 5,89 cm 5,78 cm -1,87%

Area 1,47 cm² 2,06 cm² 40,1%

AxialPerimeter 3,03 cm 6,48 cm 80,9%

Area 0,47 cm² 1,35 cm² 187,2%

Sagittal Perimeter 4,06 cm 5,39 cm 32,8%

Area 0,69 cm² 1,71 cm² 147,8%

The tumor’s dimensions traced according echogenicity are always smaller than the ones traced according the stiffness in all planes.Breast cancer is staged by the TNM System : Tumor Size, node status, and metastasis. Tumor Size is divided into four classes based on the maximum diameter:

T-1 is from 0 to 2 centimeters.

T-2 is from 2 to 5 cm. T-3 is greater than 5 cm .T-4 is a tumor of any size that has broken through (ulcerated) the skin, or is attached to the chest wall.

So it would be wise to check which is the most reliable imaging technique of measurement of the ‘T’ parameterrelating it to the more accurate prognostic significance and to the right choice in the therapeutic approach.

T1mi Tumor ≤1 mm in greatest dimension.

T1a Tumor >1 mm but ≤5 mm in greatest dimension.

T1b Tumor >5 mm but ≤10 mm in greatest dimension.

T1c Tumor >10 mm but ≤20 mm in greatest dimension.

Page 8: Swe on breast cancer in dense breast with considerations on tnm staging

Antonio Pio MasciotraCampobasso – Molise – Italy

Email

[email protected]

Website

www.masciotra.net

YouTube Channel

https://www.youtube.com/channel/UCgCj21nKGAhR997Ia3-QegQ

Breast cancer in dense breast as seenat Shear Waves Elastography

with discussion about the ‘T’ measurement in TNM staging