Major Epidemics in the History of Medicine .Eyler JM: Smallpox in History: The Birth, Death and...

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Transcript of Major Epidemics in the History of Medicine .Eyler JM: Smallpox in History: The Birth, Death and...

  • Major Epidemics in the

    History of Medicine

    Center for History Of Medicine and

    Archives and Rare Books

    Winter 2016

    January 6 February 3

    M04 579H

  • M04 579H Major Epidemics in the History of Medicine

    Winter 2016

    Page 1 of 23

    Major Epidemics in the History of Medicine M04 579H

    Syllabus

    Description/Objectives:

    Points to be emphasized include the world-wide effects of such epidemics (bubonic plague), the discovery of vaccination and the ability to completely eradicate a major disease (small pox), the importance of insect-vector diseases, such as malaria and yellow fever, as well as the emergence into the developed world of new insect-carried disease such as dengue fever, Zika virus disease, and chikungunya, venereal disease and epidemics of modern times such as influenza and AIDS. Most of the diseases to be discussed are still prevalent, and patients suffering from these diseases will be seen and treated by the medical students during their medical career. At the end of this course, students will be able to:

    Identify some of the most important and devastating epidemics in the history of medicine, beginning in antiquity and continuing into the 21st century;

    Describe the clinical and pathological findings of each disease, and how medical science responded to the threat of each epidemic;

    Understand how immunization and treatments to reduce the spread of epidemics were developed by medical science; and

    Understand that the threat of epidemic disease still occurs in spite of past advances in medicine and public health.

    Locations: Center for History Of Medicine, Bernard Becker Medical Library, 6th floor; Archives and Rare Books, Bernard Becker Medical Library, 7th floor

    Time: Wednesday, 3:30 5:30 p.m. (unless otherwise noted) Format: 3:30 5:00 p.m. Students discuss and summarize assigned articles Center for History Of Medicine; 5:00 5:30 p.m. Examination of Archival Materials --- Archives and Rare Books

    Subjects to be discussed:

    Week I The Black Death: Bubonic Plague

    Week II Smallpox and Vaccination

    Week III Insect-Carried Diseases: Malaria and Yellow Fever

  • M04 579H Major Epidemics in the History of Medicine

    Winter 2016

    Page 2 of 23

    Week IV Tuberculosis and Syphilis

    Week V Modern Epidemics: Influenza and AIDS

    Participants:

    WUSM I Students

    Becker Library Archives and Rare Books Staff Ms. Elisabeth Brander, Rare Book Librarian

    Mr. Stephen Logsdon, Archivist Ms. Martha Riley, Rare Books Cataloger & Archivist Mr. Philip Skroska, Visual and Graphic Archivist

    Faculty

    Robert M. Feibel, MD, Professor of Clinical Ophthalmology and Acting Director of the Center for History Of Medicine Ernie-Paul Barrette, Associate Professor of Medicine, Division of Infectious Diseases

    Contact: Ms. Debra Knox Deiermann, 314/362-2725; CfHOM@wusm.wustl.edu

  • M04 579H Major Epidemics in the History of Medicine

    Winter 2016

    Page 3 of 23

    Major Epidemics in the History of Medicine M04 579H Readings

    Week I The Black Death: Bubonic Plague

    Required reading Sherman IW: Power of Plagues, Chapter 4: An Ancient Plague, the Black Death

    Recommended reading Cohen J, Powderly, WG: Infectious Diseases, 2nd Edition Gage KL: Chapter 120: Plague

    https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323045797001209 Individual assignments 1. Berche P: Louis Pasteur, From Crystals of Life to Vaccination http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2012.03945.x/epdf 2. Blevins SM: Robert Koch and the Golden Age of Bacteriology http://www.sciencedirect.com/science/article/pii/S1201971210023143 3. Zietz BP: The History of the Plague and the Research on the Causative Agent Yersinia pestis http://www.sciencedirect.com/science/article/pii/S1438463904702771 4. Butler T: Plague History: Yersins Discovery of the Causative Bacterium in 1894 Enabled, in the Subsequent Century, Scientific Progress in Understanding the Disease and the Development of Treatments and Vaccines http://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12540/epdf 5a. CDC Morbidity and Mortality Weekly Report: Human Plague United States, 2015 http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6433a6.htm 5b. Kugeler KJ: Epidemiology of Human Plague in the United States, 1900-2012 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285253/pdf/14-0564.pdf 6. Barras V, Greub G: History of Biological Warfare and Bioterrorism http://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12706/epdf

    Week II Smallpox and Vaccination

    Required reading Sherman IW: Power of Plagues, Chapter 9: Smallpox, the Spotted Plague

    https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323045797001209http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2012.03945.x/epdfhttp://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2012.03945.x/epdfhttp://ac.els-cdn.com/S1201971210023143/1-s2.0-S1201971210023143-main.pdf?_tid=67e7d660-a367-11e5-ad12-00000aab0f27&acdnat=1450210202_79841993404b5a69f7f07081450ddf83http://www.sciencedirect.com/science/article/pii/S1201971210023143http://ac.els-cdn.com/S1438463904702771/1-s2.0-S1438463904702771-main.pdf?_tid=f79624a0-5d7c-11e5-bb17-00000aacb35e&acdnat=1442522881_93170ccb846d34be7cf207f776e7c80ehttp://ac.els-cdn.com/S1438463904702771/1-s2.0-S1438463904702771-main.pdf?_tid=f79624a0-5d7c-11e5-bb17-00000aacb35e&acdnat=1442522881_93170ccb846d34be7cf207f776e7c80ehttp://www.sciencedirect.com/science/article/pii/S1438463904702771http://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12540/epdfhttp://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12540/epdfhttp://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12540/epdfhttp://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12540/epdfhttp://www.cdc.gov/mmwr/preview/mmwrhtml/mm6433a6.htmhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285253/pdf/14-0564.pdfhttp://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12706/epdfhttp://onlinelibrary.wiley.com/doi/10.1111/1469-0691.12706/epdf

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    Recommended reading Cohen J, Powderly, WG: Infectious Diseases, 2nd Edition: Practice Point: d) Initial Management of a Suspected Outbreak of Smallpox

    Individual assignments 1. Eyler JM: Smallpox in History: The Birth, Death and Impact of a Dread Disease

    http://www.sciencedirect.com/science/article/pii/S0022214303001021

    2. Rutkow IM: Zabdiel Boylston and Smallpox Inoculation http://archsurg.jamanetwork.com/article.aspx?articleid=392281

    3a. Smith GF: Edward Jenner and the Small Pox Vaccine http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342363/pdf/fimmu-02-00021.pdf

    3b. Brunham RC: In Celebration of the 200th Anniversary of Edward Jenners Inquiry into the Causes and Effects of the variolae vaccinae

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342363/pdf/fimmu-02-00021.pdf

    4. Semba RD: The Ocular Complications of Smallpox and Smallpox Immunization

    http://archopht.jamanetwork.com/article.aspx?articleid=415346

    5a. Albert, MR: The Last Smallpox Epidemic in Boston and the Vaccination Controversy, 1901-1903 http://www.nejm.org/doi/pdf/10.1056/NEJM200102013440511 5b. Parmet WE: Individual Rights versus the Publics Health 100 Years after Jacobson v. Massachussetts http://www.nejm.org/doi/pdf/10.1056/NEJMp048209 6. Stern AM: The History of Vaccines and Immunization: Familiar Patterns, New Challenges http://content.healthaffairs.org/content/24/3/611.full.pdf 7. Clemmons NS: Measles United States, January 4 - April 2, 2015

    http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6414a1.htm 8. Jacobson RM: Vaccine Hesitancy http://www.sciencedirect.com/science/article/pii/S0025619615007193

    http://ac.els-cdn.com/S0022214303001021/1-s2.0-S0022214303001021-main.pdf?_tid=e41308ee-921f-11e5-9164-00000aab0f02&acdnat=1448310317_5016457de7166856ec83a8261618efbahttp://www.sciencedirect.com/science/article/pii/S0022214303001021http://archsurg.jamanetwork.com/article.aspx?articleid=392281http://archsurg.jamanetwork.com/article.aspx?articleid=392281http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342363/pdf/fimmu-02-00021.pdfhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342363/pdf/fimmu-02-00021.pdfhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342363/pdf/fimmu-02-00021.pdfhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342363/pdf/fimmu-02-00021.pdfhttp://archopht.jamanetwork.com/article.aspx?articleid=415346http://archopht.jamanetwork.com/article.aspx?articleid=415346http://www.nejm.org/doi/pdf/10.1056/NEJM200102013440511http://www.nejm.org/doi/pdf/10.1056/NEJMp048209http://www.nejm.org/doi/pdf/10.1056/NEJMp048209http://www.nejm.org/doi/pdf/10.1056/NEJMp048209http://content.healthaffairs.org/content/24/3/611.full.pdfhttp://content.healthaffairs.org/content/24/3/611.full.pdfhttp://content.healthaffairs.org/content/24/3/611.full.pdfhttp://www.cdc.gov/mmwr/preview/mmwrhtml/mm6414a1.htmhttp://www.cdc.gov/mmwr/preview/mmwrhtml/mm6414a1.htmhttp://ac.els-cdn.com/S0025619615007193/1-s2.0-S0025619615007193-main.pdf?_tid=07ee7d90-984a-11e5-9d0c-00000aacb362&acdnat=1448988123_f48fd8ebe3cdfab0955017ce9dec712dhttp://www.sciencedirect.com/science/article/pii/S0025619615007193

  • M04 579H Major Epidemics in the History of Medicine

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    Week III Insect-