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FIRST AID IMMUNOLOGY 

1. Outer cortex of lymph node contain which cells?

2. Which area of lymph node is not well developed in digeorge syndrome?

3. Lymph drainage of lateral side of dorsum of foot?4. Lymph drainage of rectum below pectinate line?

5. T cells are found in which pulp of spleen?

6. Thymus is derived from?7. MHC gene is located on which chromosome?

8. APC cells expresses which MHC class?

9. Grave disease is associated with why HLA subtype?10. NK cells uses what for induction of apoptosis?

11. Antibodies are produced by which cells ?

12. Positive selection is done in which part of thymus?13. Name APCs??

14. Costimulatory signal is given by interaction between?

15. Th1 cells inhibited by?

16. Which portion of IGM and IGg fixes complement?17. Light chain contributes to which fraction of anticody?

18. Main antibody in secondary response to antigen?

19. Colostrum contain which antibody?20. IgE mediates immunity against worms by activating ?

21. Mature B lymphocytes express ------ on their surfaces?

22. Most abundant antibody in blood?23. Antibody with lowest concentration in serum?

24. Classic complement pathway mediated by which antibody?

25. Neutrophil chemotaxis done by which complement?26. C1 esterase inhibitor def causes which disease?

27. Decay accelerating factor causes which disease?

28. antibody pentamer in serum ??29. Name the opsonins in bacterial defense?

30. Recurrent Neisseria bacteremia is caused due to def of?

31. Which IL inhibit inflammation?32. Name the IL that supports growth factor and differentiation of bone marrow stem

cells ?

33. IL causes fever and stimulates production of acute phase reactants?34. Cytokine mediates septic shock ?

35. Name unique marker of NK?

36. All cells have MHC-I except?37. Receptor for EBV on B cells ?38. Self reactive T cells become non reactive without Costimulatory molecule ... This

 phenomenon is called ??

39. IgA in Breast milk is form of which immunity ?40. Antibody involved in type 1 HSR?

41. Cytotoxic hypersensitivity is which type of hypersensitivity?

42. In erythroblastosis fetalis which Ig is involved?

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43. Hashimoto thyroiditis involves which type of hypersensitivity ?

44. Rheumatic fever is which type of HSR?

45. Anti mitochondrial antibody associated disorder?46. Mixed connective tissue disease associated with which autoantibody?

47. Drug induced sle associated with hitch antibody?

48. T cell deficiencies produce which infections mostly?49. In Brutton aggamaglobinemia defect is in which gene?

50. Jobs syndrome increases which immunoglobulin ?

51. Digeorge syndrome is failure to develop?52. Sinus and lung infections are caused by which Ig deficiency?

53. SCID is due to defective?

54. Wiskott-Aldrich syndrome presentation triad is ??55. Graft from twin or clone is called ?

56. Rejection occurs within minutes of transplantation is called ?

57. Vasculitis of graft vessels with dense interisitial lymphocytic infiltrate is feature ofwhich type f rejection?

58. Most common infection in transplant recipient ?59. Target of infliximab is ?60. Target of transtuzumab is ?

61. Drug used to prevent acute transplant rejection?

62. Serum sickness is which type of hypersensitivity ?

63. In ataxia talengectasia which gene is defective?64. Contact dermatitis is which HSR?

65. Fibrinoid necrosis is hallmark of which HSR?

66. Live attenuated vaccine mainly induced which response?67. Half life of passive immunity is ?

68. IL that promotes differentiation of B cells ??

69. IL that activates NK cells?70. MAC complex is formed by?

71. IgA in circulation is in which form ?

72. Which fragment of antibody determines idiotype?73. Foreign body is phagocytosed by?

74. MHC II expressed only on?

75. HLA B27 Associated with which disease ?76. NK activity is enhanced by?

77. Lymph drainage of stomach ?

78. Lymph drainage os scrotum?79. During extreme cellular immune response which area of lymph node enlarges ?

80. Most common congenital immunoglobulin deficiency?

81. Which transplant has best allograft survival rate ??82. Most common drug induced lupus?

83. Most common cause of death in SLE?

84. Reservoir of HIV is ?85. Amyloidosis of which organ is most serious form of organ involvement?

86. Which rest for AIDS is confirmatory?

87. Complement components are synthesized mostly in?

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88. Sjogren syndrome is associated with?

89. Initial most sensitive test for SLE?

90. Patient has CRF best donor for this patient is ??91. Master switch to nucleus for induction of inflammation?

92. IL that stimulates and activates eosinophils ?

93. Methyl dopa alters which antigen on Rbc surface?94. Amyloid precursor protein is located on which chromosome?

95. Misfolded proteins are normally removed by ?

KEYS

1. B cells

2. Paracortex3. Popliteal

4. Superficial inguinal

5. White pulp6. 3 rd pharyngeal pouch

7. Chr. 68. MHC - II9. B8

10. Perforins and granzyme

11. Plasma cells

12. Thymic cortex13. Macrophage, dendritic cell, B cell

14. B7 and CD28

15. IL-1016. Fc

17. Fab

18. IgG19. IgA

20. Eosinophils

21. IgM and IgD22. IgG

23. IgE

24. IgG and IgM25. C5a

26. Hereditary angoidema

27. PNH28. IgM

29. C3b and IgG

30. C3-C8 def 31. IL-10

32. IL-3

33. IL-634. TNF-alpha

35. CD56

36. Rbc

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37. CD21

38. Anergy

39. Passive40. IgE

41. Type 2

42. ? IgG43. Typed IV

44. Type II

45. Primary biliary cirrhosis46. Anti RNP

47. Anti histone

48. Fungal ad viral49. Tyrosine kisane gene

50. IgE

51. 3rd and 4th pharyngeal pouches52. Selective IgA deficiency

53. IL-2 receptor 54. Thrombocytopenia , infections and eczema55. Syngeneic graft

56. Hyperacute rejection

57. Acute rejection

58. CMV59. TNF-a

60. Erb-B2

61. Daclizumab62. Type III

63. ATM gene

64. Type IV65. TypeIII

66. Humoral

67. 3 weeks68. IL5

69. IL12

70. C5b-9f 71. Monomer 

72. Fab

73. APC74. APC

75. Psoriasis , ankylosing spondylitis , IBD and Reiter syndrome

76. IL-12, IFN-b, IFN-a77. Celiac

78. Sup inguinal

79. Paracortex80. IgA

81. Corneal transplant

82. Procainamide

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83. Infections

84. Dendritic cells

85. Kidney86. Western blot

87. Hepatocyte

88. Rheumatoid arthritis89. ANA

90. Twin

91. NFkb92. IL-5

93. Rh antigen

94. Ch.2195. Proteasomes

   REGARDS    DR NOOR UL BASAR