2a Embryonic Development.ppt

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    Survey of Embryonic

    Development

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Diagrams showing the size of a human conceptus from fertilization to the early fetal stage

    Fertilization1-week conceptus

    2-week conceptus

    3-week embryo

    Embryo

    4-week embryo

    5-week embryo

    -week embryo

    !-week embryo

    "-week embryo

    #-week fetus

    12-week fetus

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    $perm penetration an% the cortical reaction &slow block to polyspermy

    Fusion of oocytean% sperm plasmamembranes

    'orticalreaction

    $perm nucleus engulfe%by oocyte cytoplasm

    (ocyte cytoplasm'ortical granule

    (ocyte plasmamembrane

    E)tracellularspace

    *ona pelluci%a

    $perm nucleus

    +ranulosa cellsof corona ra%iata

    ,crosomalreaction

    ,crosome

    (ocyte insecon% meiotic%iision

    First polar bo%y

    *ona pelluci%a'orona ra%iata$perm

    &a.

    &b.

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Eents imme%iately following sperm penetration

    Daughtercells

    ,naphase offirst cleaage%iision

    $perm an% oumchromosomes

    *ygote

    /ale pronucleus

    /itotic spin%le

    'entriole

    Female pronucleus

    0olarbo%ies

    (um

    nucleus

    $perm pro-nucleus

    Detache%sperm tail

    $perm

    E)tracellular space

    $econ% meiotic %iisionof oocyte

    $econ% meiotic %iisionof first polar bo%y

    'oronara%iata

    *onapelluci%a

    &a.

    &b.

    &c.

    &%.

    &e.

    &f.

    &g.

    &h.

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    lastocystcaity

    Degeneratingzonapelluci%a

    nner cellmass

    lastocystcaity

    rophoblast

    *ygote&fertilize%egg.

    4-cell stage2 %ays

    /orula3 %ays

    Early blastocyst4 %ays

    mplanting blastocyst %ays

    'aity ofuterus

    terus

    En%ometrium(ulation

    (ary

    Fertilization&sperm meets egg.

    terine tube

    (ocyte&egg.

    $perm

    &a. &b. &c. &%. &e.

    &a.

    &b.

    &c.

    &%.

    &e.

    'leaage from zygote to blastocyst

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    mplantation of the blastocyst

    En%ometrial stromawith bloo% esselsan% glan%s

    $yncytiotrophoblast

    'ytotrophoblastnner cell mass&future embryo.

    8umen of uterus

    terine en%ometrial

    epitheliumnner cell mass

    rophoblast

    En%ometrium

    lastocyst caity8umen of uterus

    &b. &c.

    &a.

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Formation of the three primary germ layers

    ilayere%

    embryonic %isc

    ,mniotic sac

    ,mniotic sac &amnion.9olk sac

    'ut e%ge

    of amnion

    8eft

    7ight

    0rimitiestreak

    ypoblastEpiblast

    9olk sac

    Future openingbetween mouthan% pharyn)

    ea%

    &b. : : : turne% #6;&c. 3-D iew &%. $ection iew in &e.

    &a. Embryo&$ee Figure 2":!b.

    &e. ilayere% embryonic %isc< lateral-superior iew

    9olk sac

    ail

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Formation of the three primary germ layers

    ea%

    'ut e%geof amnion

    9olk sac&cut e%ge.

    7ight8eft

    $ections

    ail

    0rimitie streak

    0rimitie

    streak

    En%o%erm

    /eso%erm Definitieen%o%erm

    Epiblastypoblast

    Ecto%erm

    &f. ilayere% embryonic

    %isc< superior iew

    &g. 14=15 %ays

    &h. 1 %ays

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    >eurulation

    &a. 1! %ays

    &b. 1# %ays

    ,mnion

    ,mniotic caity

    >eural plate

    Ecto%erm

    /eso%erm

    >otochor%

    En%o%erm

    9olk sacail

    ea%

    'ute%ge of

    amnion

    0rimitiestreak

    $urfaceecto%erm

    >eural

    plateFutureneural

    crest

    >otochor%

    >otochor%

    'ut e%ge

    of amnion>eural

    plate

    0rimitieno%e0rimitiestreak

    >eural grooe>euralfol%

    >euralgrooe >eural

    crest

    8eft 7ight

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    (i""ue" #erive# from the three

    germinal layer") Ecto#erm* nervou" ti""ue"$ epi#ermi"

    an# melanocyte"

    ) Me"o#erm* bone"$ mu"cle"$me"enchyme$ repro#uctive "y"tem$

    urinary "y"tem

    ) En#o#erm* #ige"tive "y"tem$ re"piratory"y"tem$ en#ocrine "y"tem

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Eents of placentation< early embryonic %eelopment< an% e)traembryonic membrane formation

    /aternalbloo% essels

    8acuna &interillusspace. containingmaternal bloo%

    Endometrium

    ,mniotic caity

    0rimarygerm layers?

    @ Ecto%erm'horionic illus

    'horion

    ,mnion

    9olk sac

    E)traembryonicmeso%erm

    'horionbeing forme%

    Lumen of uterus

    0roliferatingsyncytiotrophoblast

    'ytotrophoblast

    ,mniotic caityilayere%embryonic%isc?@ Epiblast@ ypoblast

    En%ometrialepithelium

    @ /eso%erm

    @ En%o%erm

    Forming

    bo%y stalk,llantois

    E)tra-embryoniccoelom

    &a. !1A2-%ay implanting

    blastocyst

    &b. 12-%ay implante% blastocyst

    &c. 1-%ay embryo

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    Embryonic membrane"

    ) +mnion* enca"e" an# protect" embryo

    again"t mechanical an# temperature

    trauma) ,ol- "ac* tran"fer" nutrient" to embryo

    .eplace# by placenta in human"

    ) +llantoi"* repo"itory of embryo /a"te".eplace# by placenta in human"

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Deci%ua basalis

    /aternal bloo%

    'horionic illus

    mbilical bloo%essels inumbilical cor%

    ,mnion

    ,mniotic caity

    9olk sac

    E)traembryonic

    coelom

    'horion

    Deci%uacapsularis

    Lumen

    of uterus

    &%. 41A2-week embryo

    Eents of placentation< early embryonic %eelopment< an% e)traembryonic membrane formation

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Eents of placentation< early embryonic %eelopment< an% e)traembryonic membrane formation

    0lacenta

    Deci%ua basalis

    'horionic illi

    9olk sac

    ,mnion

    ,mnioticcaity

    mbilical cor%

    terus

    8umen ofuterus

    Deci%ua

    capsularis

    &f. 13-week fetus

    E)traembryonic

    coelom

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    Human Anatomy and Physiology,7eby Elaine Marieb & Katja Hoehn

    Copyright 27 !ear"on E#ucation$ %nc$publi"hing a" 'enjamin Cumming"

    Eents of placentation< early embryonic %eelopment< an% e)traembryonic membrane formation

    /yometrium

    /aternaleins

    /aternalarteries

    mbilical arteries

    mbilical ein'onnection toyolk sac

    'horionic illuscontaining fetalcapillaries

    Fetal arterioleFetal enule

    ,mnion

    &g.

    mbilical cor%

    /aternal bloo%in lacuna

    &interillus space.

    $tratum basalis ofen%ometrium

    /aternal portion

    of placenta&%eci%ua basalis.

    Fetal portion ofplacenta &chorion.