Title HONORS RESEARCH IN BMB - Boston University · 2014-01-13 · Title HUMAN INFECTIOUS DISEASE:...

HONORS RESEARCH IN BMBTitle

StaffProfessorCAS BB 401/402 FOR BMB MAJORS ONLYNotes

Lecture Times

Text(s)

Students must graduate with a minimum major GPA of 3.5 in order to receive honors credit; Participation in 2 semesters of the 1 credit Honors Semester (CAS BB 497/498); completion of CAS BB 401/402; completion and defense of senior thesis

Grading

Prereq Senior standing, a 3.5 GPA in Biology with a 3.0 overall. Approval by the Research Honors Committee & Director of BMB

Discussion/Lab Times

CAS BB 401/402Course #

Provides students with an opportunity to work closely with faculty who serve asintellectual and technical mentors in their exploration of molecular biology and ̄biomedical research. The potential for learning, scholarship and academic growth is aunique opportunity for BMB students to translate formal class work into research practice.

Summary

MOLECULAR BIOLOGY LABTitle

GilmoreProfessorPERMISSION REQUIREDNotesNONELecture Times

Xeroxed lab note packetText(s)

Midterm (20%); final (20%); lab reports (35%); lab participation and preparation (25%)Grading

Prereq BI 552; consent of Instructor

Discussion/Lab Times A1 TR 1:00-5:00

CAS BB 522Course #

Introduction to techniques of molecular and cellular biology research, includinganalysis ofDNA and protein molecules by techniques such as restriction enzyme digestions, PCR, subcloning, DNA sequencing, computer-based sequence analysis, tissue culture, reportergene assays, indirect immunofluorescence, and yeast molecular biology.

Summary

HUMAN ANATOMYTitle

Co; Pasino (lab)ProfessorNOT FOR BIOLOGY CONCENTRATION CREDITNotesA1 MWF 11:00-12:00Lecture Times

1) Marieb. Human Anatomy. 6th Edition 2) Custom Lab Manual available at BU Bookstore

Text(s)

3 midterm lecture exams; 1 cumulative lecture final, 2 laboratory practical examsGrading

Prereq BI 105 or equivalent

Discussion/Lab Times C1

C2C3C4

D1D2D3D4

9:30-11:3012:30-2:303:30-5:306:00-8:00

8:30-10:3012:30-2:303:30-5:306:00-8:00

E1E2E3

LAB9:30-11:3012:30-2:303:30-5:30

12:30-2:303:00-5:00

CAS BI 106Course #

Intensive study of the structure of the human body systems: skeletal, muscular, nervous, respiratory, circulatory, lymphatic, integumentary, endocrine, digestive, urinary, and reproductive systems. Required dissection of preserved specimens, plus computer simulations. This course is intended for preprofessional students in several allied health majors, and it functions as a prerequisite for Gross Anatomy.

Summary

BIOLOGY IITitle

Monette, Spilios, EldredProfessorNotes

A1 MWF 10:00-11:00 A2 MWF 12:00- 1:00 A3 MWF 2:00-3:00Lecture Times

1) Sadava, et. al. Life: The Science of Biology, 10th ed., Sinauer Publ., 20142) Spilios. Principles of Biology II Laboratory Manual. 2014.

Text(s)

Four hourly exams, lecture 68%, lab 32%Grading

Prereq High school biology and one semester college chemistry required.

Discussion/Lab Times B7

C1C2C3C4C5C6C7

MTTTTTTT

C8C9D2D3D4D5D6D7

TTWWWWWW

4:00-7:009:00-12:009:00-12:009:00-12:001:00-4:001:00-4:001:00-4:005:00-8:00

5:00-8:005:00-8:00 8:00-11:008:00-11:0012:00- 3:001:00-4:0012:00-3:004:00-7:00

D8E1E2E3E4E5E6

WRRRRRR

E7E8E9F1

5:00-8:005:00-8:005:00-8:0010:00-1:00

LAB CA4:00-7:009:00-12:009:00-12:009:00-12:001:00-4:001:00-4:001:00-4:00

CAS BI 108Course #

Principles of biochemistry, cell and molecular biology, neurobiology, genetics, and physiology. This course counts toward a biology major or divisional credit and toward a medical school biology requirement.

Summary

HUMAN INFECTIOUS DISEASE: AIDS TO TUBERCULOSISTitle

CoProfessorNOT FOR BIOLOGY CONCENTRATION CREDITNotesA1 MWF 9:00-10:00Lecture Times

1) Cowan and Bunn. Microbiology Fundamentals, A Clinical Approach. McGraw-Hill 2) Custom Lab Manual for BI114 by Co

Text(s)

4 lecture exams; laboratoryGrading

Prereq None

Discussion/Lab Times B1 MW C1

TRTRTR

3:00-4:30 9:30-11:001:30-3:003:30-5:00

LAB TIMES10:30-12:001:00-2:30

CAS BI 114Course #

A non-majors course that surveys the world’s major infectious diseases such as AIDS, hepatitis, herpes, influenza, malaria, tuberculosis and others. We will discuss the biological and immunological basis for infection as well as the cause, effect on history, pathology and cure or treatment for each disease. We will also discuss immunological topics affecting modern society such as antibiotic resistance, vaccines and the microbiome.

Summary

BIOLOGY II (Honors)Title

Dionne, Loechler, Spilios (lab)ProfessorPERMISSION REQUIREDNotesA1 TR 12:30-2:00Lecture Times

1)Sadava, et. al. Life: The Science of Biology,10th ed., Sinauer Publ., 20142)Spilios. Principles of Biology II Laboratory Manual. 2014.

Text(s)

TBAGrading

Prereq 3.2 GPA after fall semester and a 5 on Biology AP Exam (or equivalent); or consent of the instructor

Discussion/Lab Times C1

1:00-4:001:00-4:00

B1 FLAB DISCUSSION

10:00-11:00

CAS BI 118Course #

BI 118 is an alternative to BI 108 for students with a strong high school background in biology. Lectures move at a quicker pace and go into greater depth on selected topics. The discussion sessions review important concepts, introduce related material, and may include readings from the primary literature. The first 2/3 of the BI118 laboratory is the same as the BI108 laboratory; however, the last third involves student projects stressing inquiry-based learning.

Summary

SOCIOBIOLOGYTitle

TranielloProfessorNOT FOR BIOLOGY CONCENTRATION CREDITNotesA1 TR 12:30-2:00 Lecture Times

Wilson, E.O., On Human Nature and selected readingsText(s)

Three exams; weekly participation in discussion section and lecture/ section assignments and projects

Grading

Prereq None

2:00-3:002:00-3:00

DISCUSSION

CAS BI 119Course #

The biological basis of animal social behavior and the evolution and ecology of societies. Topics include the natural history of social behavior, genetics and development of behavior, altruism, mate choice, mating systems, parental care, human sociobiology, evolutionary psychology, and the impact of evolutionary theory on social thought. Fulfills a natural science divisional requirement.

Summary

READINGS IN BIOLOGYTitle

StaffProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT (2 CREDITS)NotesArrangedLecture Times

Text(s)

Grading

Prereq Consent of instructor and permission required.

CAS BI 171/172Course #

Library research for students at the freshman level, on a well-defined topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.

May not be used as credit towards the biology major or specializations.

Summary

UNDERGRADUATE RESEARCH IN BIOLOGY ITitle

StaffProfessorCAS BB 191/192 FOR BMB MAJORS ONLY (2 CREDITS)NotesArrangedLecture Times

Text(s)

Grading

CAS BI 191/192 or CAS BB 191/192Course #

Research in biological science for students at the freshman level. Design and implementation of a research project in conjunction with a faculty member.

May not be used as credit towards the Biology major or specializations, or the BMB major.

Summary

INTRODUCTORY QUANTITATIVE BIOLOGYTitle

TbaProfessorALSO OFFERED AS MA 196NotesA1 TR 11:00-12:30 Lecture Times

Text(s)

Grading

Prereq MA 121 or MA 123 and BI 107 or consent of instructor; coreq- BI 108 or 118.

Discussion/Lab Times A2 T 4:00-5:00

DISCUSSION

CAS BI 196Course #

An introduction to the application of mathematics to problems in biology, with particular emphasis on questions arising from ecology, physiology, neuroscience, and genetics. Major focus on building mathematical models for biology problems and analysis with graphical and mathematical techniques.

Summary

GENETICS (CM)Title

CelenzaProfessorNotes

A1 TR 11:00-12:30 Lecture Times

1)Hartwell et. al. Genetics: From Genes to Genome. McGraw-HiII Edition: 4th edition. 2) Recommended, but not required: Solutions Manual for the text. (Custom printing will be available through the BU bookstore).

Text(s)

80% avg. of four exam scores given during the semester. 20% discussion.

Grading

Prereq BI 108/118 required, BI 203 recommended; Co-requisite:CH 203 .

B2B3B4C1

D1D2D3D5

12:00-1:0012:00-1:001:00-2:002:00-3:008:00-9:00

8:00-9:0012:00-1:002:00-3:002:00-3:00

DISCUSSION

CAS BI 206Course #

The study of the transmission, organization, expression, and evolution of the genetic material.

Summary

INTENSIVE GENETICS (CM)Title

Celenza, LoechlerProfessorRECOMMENDED FOR BMB AND BIOLOGY CMG STUDENTSNotesA1 TR 11:00-12:30Lecture Times

1)Hartwell et. al. Genetics: From Genes to Genome,McGraw-HiII. 4th edition. 2)Recommended, but not required: Solutions Manual for the text. (Custom printing will be available through the BU bookstore).

Text(s)

80% avg. of four exam scores given during the semester. 20% discussion.Grading

Prereq BI 108/118 and BI 203/213 required; Co-requisite: CH 203

B2D1D2E1E2

MMWMTT

12:00-1:002:00-3:002:00-3:0011:00-12:0010:00-11:005:00-6:00

DISCUSSION

CAS BI 216Course #

An intensive general genetics course that covers classical Mendelian and molecular genetics and examines the use of these principles in studying cells, organisms and populations. Genetics is a broad subject that requires the understanding of a large number of techniques; thus much of the course is spent learning these techniques and their application to experimental data. Therefore, students not only need to memorize material, but also must learn to solve problems.

Summary

MARINE BIOLOGY (EBE)Title

BustonProfessorNotes

A1 MWF 3:00-4:00Lecture Times

Castro & Huber. Marine Biology. 9th EditionText(s)

Three exams, participation in discussion.Grading

Prereq BI 107 or consent of instructor.

B2C1C2C3E1

WWRTTR

10:00-11:004:00-5:002:00-3:0010:00-11:002:00-3:001:00-2:00

9:00-10:0010:00-11:00

DISCUSSION

CAS BI 260Course #

The principle objective of this course is to provide students with an introduction to marine life and the ocean environment. It is a great course for anybody with an interest in the ocean who has had Biology I (BI107). This course is the prerequisite course for the BUMP Marine Semester, and a required course for BU Marine Program (BUMP) concentrators. The course begins by covering the basics of physical and chemical oceanography. This provides the context within which the ecology, evolution, behavior and conservation of marine organisms are considered. The course is aimed at sophomores in Biology and Marine Science, as well as other students interested in the relationship ҈that humans have with the sea.

Summary

StaffProfessorNOT FOR BIOLOGY CONCENTRATION CREDIT ( 2 CREDITS)NotesArrangedLecture Times

Text(s)

Grading

Library research, for students on the sophomore level, on a well-definded topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.

May not be used as credit towards the Biology major or specializations.

Summary

FUNDAMENTALS OF BIOLOGY IITitle

CelenzaProfessorSEVEN YEAR MEDICAL STUDENTS ONLYNotesA1 TR 11:00-12:30 Lecture Times

1) Hartwell et. al. Genetics: From Genes to Genome. McGraw-HiII Edition. 4th edition. 2) Recommended, but not required: Solutions Manual for the text. (Custom printing will be available through the BU bookstore).

Text(s)

80% avg. of four exam scores given during the semester. 20% Discussion.Grading

Prereq Must be enrolled in the seven-year medical program

B4C1D3

12:00-1:002:00-3:008:00-9:002:00-3:00

DISCUSSION

CAS BI 282Course #

The study of the transmission, organization, expression,and evolution of the genetic material.

Summary

UNDERGRADUATE RESEARCH IN BIOLOGY IITitle

Text(s)

Grading

Prereq Consent of Instructor and permission required.

Research in biological science for students at the sophomore level. Design and implementation of a research project in conjunction with a faculty member.

May not be used as credit towards the Biology major or specializations, or the BMB major.

Summary

VERTEBRATE ZOOLOGY Title

WassermanProfessorNotes

A1 TR 12:30-2:00Lecture Times

Pough, et al. Vertebrate Life. 9th editionText(s)

Two exams, lab quizzes and participation.Grading

Prereq BI 107

2:00-5:00 9:00-12:00

CAS BI 302Course #

To study the phylogeny, natural history, adaptation and taxonomy of main vertebrate groups from primitive fish to mammals. The course stresses the evolutionary changes in reproductive, foraging and locomotive strategies of modern representative.

Summary

ECOLOGY (EBE)Title

StewartProfessorNotes

Molles. Ecology. 6th EditionText(s)

Two hourly exams and final. Required weekly lab. Research paper and oral presentation.Grading

Prereq BI 107 and BI 108; or consent of instructor.

B1C1D1E1F1

2:00-5:002:00-5:002:00-5:002:00-5:002:00-5:00

CAS BI 303 Course #

Evaluation of patternsand processes in nature and an in-depth analysis of ecological relationships at the individual, population, community and ecosystem levels.

Summary

BIOGEOGRAPHYTitle

O’Connor ProfessorINDEPENDENT. ALSO OFFERED AS GE 307NotesA1 W 4:00-7:00Lecture Times

TBAText(s)

Grading

Prereq GE 101 and BI 107

CAS BI 307Course #

Examines the spatial distribution of plants and animals from historical, ecological, and analytical perspectives. Environmental and human influences on species distribution, abundance, and diversity are considered, as are changes resulting from past and projected climate change.

Summary

SYSTEMS PHYSIOLOGY (PN)Title

Widmaier, Seliga (lab)ProfessorPREFERENCE GIVEN TO CAS BIO MAJORS IN THE SPRING, BIOENG. IN THE FALL.NotesA1 TR 12:30 - 2:00Lecture Times

1) Vander’s. ҈Human Physiology: The Mechanisms of Body Function. 13th edition2)Lab manual by Rycroft, et al

Text(s)

Two hourly exams, final exam, lab quizzes and write ups, cummulative lab final Grading

Prereq BI 108 or equivalent, and Introductory Chemistry

B1B2C1C2C3

C4C5D1D2D3

2:00-5:006:00-9:009:00-12:002:00-5:002:00-5:00

6:00-9:006:00-9:009:00-12:009:00-12:002:00-5:00

D4E1E2E3F1

6:00-9:009:00-12:002:00-5:006:00-9:009:00-12:00

CAS BI 315 Course #

Examines the structure and function of the body’s major organ systems (nervous, endocrine, circulatory, respiratory, digestive and urinary) at the cell, tissue and organ levels. Special emphasis on regulatory and integrative aspects of feedback systems underlying the maintenance of optimal internal state required for survival in a dynamic environment.

Summary

PRINCIPLES OF NEUROSCIENCE (PN)Title

Dionne, HoProfessorNotes

Purves, et al. Neuroscience. 5th Edition. Sinauer Associates, Inc.Text(s)

Two midterms and a final exam. Grading

Prereq BI 203 or consent of instructor. BI 315 recommended.

B1B2B3

3:00-4:003:00-4:001:00-2:00

DISCUSSION

CAS BI 325Course #

Fundamentals of structure and function of the nervous system. Topics include cell signaling and communication, sensory and motor systems, neural basis of learning and memory, and brain control of sleep states.

Summary

Text(s)

Grading

Library research, for students on the junior level, on a well-defined topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.

Summary

IMMUNOLOGY (CM)Title

SiggersProfessorNotes

Peter Parham. The Immune System .3rd Edition. Garland Science Publishing, NY, NY Text(s)

Lecture: 5 Exams 90%; Discussion: 10%Grading

Prereq BI 203; BI 206

B1C1D1E1

8:30-9:3012:00-1:008:30-9:302:00-3:00

DISCUSSION

CAS BI 385 Course #

The constituents and regulation of mammalian immune systems are described at thelevels of the gene, protein, and cell. Topics include nonspecific and T cell and B cell recognition and responses, genetics of immune receptors, signaling pathways, inflammation, tolerance, memory, evolution, manipulation of defense systems, hypersensitivities, auto immunity and transplantation.

Summary

UNDERGRADUATE RESEARCH IN BIOLOGY IIITitle

StaffProfessorCAS BB 391/392 FOR BMB MAJORS ONLY (2 OR 4 CREDITS)NotesArrangedLecture Times

Text(s)

Grading

CAS BI 391/392 OR CAS BB 391/392Course #

Research in biological science for students at the junior level. Design and implementation of a research project in conjunction with a faculty member.

Students must choose 4 credits to recieve credit towards their major.

Note Biology Majors: Up to 8 credits of research may be used toward Biology major andspecializations. 4 credits may also be used toward the three-lab requirement. Note BMB Majors: Only 4 credits of research may be applied to the BMB major.

Summary

HONORS RESEARCH IN BIOLOGY Title

StaffProfessorNotes

Lecture Times

Text(s)

Student must graduate with a minimum major GPA of 3.5 in order to receive honors credit; One semester of the 2-credit research seminar (CAS BI 497/498); Two semesters of mentored research (CAS BI 401/402); Completition and defense of written senior thesis

Grading

Prereq Senior standing, a 3.5 GPA in Biology with a 3.0 overall. Approval by the Research & Honors Committee

CAS BI 401/402 Course #

Provides students with an opportunity to work closely with faculty who serve asintellectualand technical mentors in their exploration of biological research.Honors students also participate in a 2-credit research seminar, providing exposure to a broad range of current science in the Biology research community.

Summary

HERPETOLOGY Title

Schneider, WarkentinProfessorNotes

A1 TR 9:30 AM - 11:00 AMLecture Times

Herpetology, 3rd edition by Pough, Andrews, Cadle, Crump, Savitsky and WellsText(s)

Lecture Participation (10%), Midterm & Final Lecture Exams (30%), Midterm & Final Lab Exams (20%), Field Trip Participation & Notebook (20%), Term Paper (20%)

Grading

Prereq BI107 or equivalent. Recommended: BI 302 (Vertebrate Zoology) or equivalent.

Discussion/Lab Times B1 W 3:00-6:00

CAS BI 416Course #

Examines diversity, life history development, physiology, behavior, ecology and evolution of amphibians and reptiles. Field trips (including required Spring Break trip to Florida). Course will be offered every other year.

Summary

BIOCHEMISTRY II Title

KornbergProfessorALSO OFFERED AS CH 422NotesA1 MWF 9:00-10:00Lecture Times

Voet,Voet & Pratt. 2013.Fundamentals of Biochemistry. John Wiley & Sons, Inc. 4th EditionText(s)

Hour exams, lab, final.Grading

Prereq BI 421/CH 421

B1B2B3B4B5

10:00-2:003:00-7:006:00-10:001:00-5:005:30-9:30

C1C2C3

LAB DISCUSSION

8:00-9:0010:00-11:0011:00-12:00

CAS BI 422 Course #

Cell metabolism, with special emphasis on the uptake of food materials, the identity, integration and regulation of catabolic, anabolic and anaplerotic routeand the generation and utilization of energy. Lectures will include consideration of events in prokaryotic and eukaryotic organisms.

Summary

MARINE BIOGEOCHEMISTRY Title

FulweilerProfessorINDEPENDENT. ALSO OFFERED AS ES 423NotesA1 TR 12:30-2:00Lecture Times

TBA, class handoutsText(s)

Class participation, readings and/or problem sets, examsGrading

Prereq One year college chemistry, or BUMP semester, or ES 144, or consent of instructor.

CAS BI 423 Course #

Over the past decades biogeochemistry has become an essential tool to further our understanding of human impacts on the globe. In this class we discuss coastal and open ocean biogeochemical cycling and how these cycles have been altered by global change. An emphasis is placed on the linkages between local and global scales. We also discuss how biogeochemical tools help unravel various environmental questions. Topics include, but are not limited to marine primary production, iron limitation and fertilization as a response to climate change, oceanic glacial-interglacial biogeochemical cycles, biogeochemical cycles in wetlands and mangroves, and impacts of nutrient pollution on the coastal ocean.

Summary

NEUROETHOLOGYTitle

Gardner, MuscedereProfessorALSO OFFERED AS NE 444NotesA1 TR 9:30-11:00Lecture Times

1)Carew, TJ (2000) Behavioral Neurobiology: The Cellular Organization of Natural Behavior. Sinauer, Sunderland MA.2)A collection of articles from the primary literature. Articles will be posted on Blackboard

Text(s)

Undergraduates: Midterm exams: 10% each, Final exam: 20%, Lecture participation: 20%, Laboratory participation and projects: 40%.

Grading

Prereq (CAS BI 107 or CAS NE 101) and (CAS BI 325 or CAS NE 203); or consent of instructor

Discussion/Lab Times W 2:00-5:00

CAS BI 444 Course #

Specialized natural behaviors reveal general principles of systems neuroscience.Examples include vocal learning in songbirds, sensory-motor integration in bats, and central pattern generators in lobsters. Read primary literature, participate in lecture discussions, and program microchips to test human perceptual and motor skills.

Summary

CELL AND MOLECULAR NEUROPHYSIOLOGY Title

LinProfessorALSO OFFERED AS NE 445NotesA1 MWF 10:00-11:00Lecture Times

Text(s)

Grading

Prereq BI 203, BI 315, NE 203, or consent of instructor

B1 F 1:00-4:00

CAS BI 445 Course #

This course discusses the neural functions at cellular and molecular levels. The principles established at these levels are extrapolate to higher brain functions. Laboratory sessions include projects using intracellular and extracellular recording techniques to investigate action potentials and synaptic potentials.

Summary

CONSERVATION BIOLOGYTitle

PrimackProfessorNotes

Primack,R. Essentials of Conservation Biology. 5th edition. Sinauer AssociatesText(s)

Exams, course paper, oral presentation, quizzes, course participation.Grading

Prereq BI 303 or consent of instructor.

A1 W 2:00-3:00

DISCUSSION

CAS BI 448Course #

The study of biological diversity and modern methods to protect it. The environmental, population, genetic, economic, legal and human factors that affect the survival of species and ecosystems will be examined for temperate and tropical communities, as well as terrestrial and aquatic habitats.

Summary

Text(s)

Grading

Library research, for students at the senior level, on a well-defined topic in biological science, chosen in conjunction with a faculty sponsor. Individual conferences and discussion with a faculty member, and paper preparation.

Summary

UNDERGRADUATE RESEARCH IN BIOLOGY IVTitle

Text(s)

Grading

Research in biological science for students at the senior level. Design and implementationof a research project in conjunction with a faculty member.

Note Biology Majors: Up to 8 credits of research maycount as electives for the Biology major or specializations. 4 credits may also be used toward the three-lab requirement. Note BMB Majors: Only 4 credits of research may be applied to the BMB major.

Summary

SYMBIOSISTitle

ZookProfessorINDEPENDENT. RECOMMENDED FOR GRADUATE STUDENTS & SENIORS IN BIOLOGY, EARTH SCIENCES, WOODS HOLE, SCIENCE EDUCATION AND MEDICINE. NotesA1 T 4:00-7:00Lecture Times

TBAText(s)

Course project (includes group and individual work), midterm and final.Grading

Prereq Senior standing or consent from instructor.

CAS BI 503Course #

Intensive exploration of a dominant survival mechanism in Earth history. Emphasis on partner integration in cell evolution; metabolic basis of the associations; the ubiquity of such associations in all ecosystems; and the study of sample symbiotic systems such as coral reefs and microbiome lichensand the human microbiome.

Summary

BEHAVIORAL ECOLOGY Title

SorensonProfessorNotes

Davies NB 2012. An Introduction to Behavioral Ecology. 4th EditionText(s)

Two exams, two papers, class participation.Grading

Prereq One upper-level course in ecology, evolution, or behavior.

2:00-3:002:00-3:00

DISCUSSION

CAS BI 508Course #

Examines the adaptive significance of behavior in an ecological context. Topics include the evolution of social behavior, mating systems, sexual selection, alternative reproductivebehaviors, life history strategies, optimal foraging, territoriality, cooperation and conflict,host-parasite co-evolution, the ecology of communication, and comparative analyses.

Summary

BIOLOGY OF NEURODEGENERATIVE DISEASESTitle

PastorinoProfessorALSO OFFERED AS NE 525NotesA1 M 9:00-10:00 W 8:00-10:00 F 9:00-10:00Lecture Times

Detailed handouts, powerpoint presentation, PDF files on course websiteText(s)

2 midterm exams 46%; final exams 24%; assignments 15%; paper presentation 15%Grading

Prereq (CAS BI 203 or CAS NE 102) and (CAS BI 325 or CAS NE 203 )

CAS BI 525 Course #

This course focuses on understanding the molecular mechanisms that are at the basis of neurodegenerative diseases and on their impact and relevance in clinical diagnosis and treatment. Neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis, Huntington Disease and Cruetzfeldt-Jacob disease are becoming more and more common since people are more exposed to pathogenic agents ( as in Cruetzfeldt-Jacob disease and Mad Cow disease) or just encounter these diseases as a result of aging ( like Alzheimer’s or Parkinson’s disease). Although very different from on another, these diseases share common mechanisms and features leading to neuronal death, including protein misfolding and aggregation, oxidative stress, impaired protein degradation, and apoptosis. This course will study howthese molecular pathways define each disease, contributing to neurodegenerative phenomena. Relevance will be given to Alzheimer’s disease.

Summary

BIOCHEMISTRY LAB II Title

TolanProfessorALSO OFFERED AS CH 528NotesA1 F 8:00-9:00Lecture Times

Text(s)

Lab preparation, lab reports, final exam.Grading

Prereq BI/CH527 or BI/CH421 or BI/CH621

B1B2B3B4B5

10:00-2:003:00-7:006:00-10:001:00-5:005:30-9:30

LAB ONLY

CAS BI 528Course #

A biochemistry lab for graduate students and currently or previously enrolled in GMS BI 751. Latter may be taken concurrently. May be taken by others who want an upper division lab. Exercises include enzymatic assays, use of radioisotopes, protein modification, characterization of membrane lipids, Western bloting, molecular modeling, and in vitro transcription/translation.

Summary

NEUROBIOLOGY OF MOTIVATED BEHAVIOR Title

BaumProfessorALSO OFFERED AS NE 545NotesA1 TR 11:00-12:30 Lecture Times

A collection of reprints and papers.Text(s)

Two hourly exams (40%); oral presentation in a group discussion session and class participation (20%); final exam (40%).

Grading

Prereq BI 315 or BI 325, or NE 203, or consent of instructor.

12:30-2:002:00-3:30

DISCUSSION

CAS BI 545Course #

This course will consider the neural integration of internal (homeostatic) and external (sensory) signals that control the expression of motivated behaviors in a variety of vertebrate species including humans. Specific topics to be considered include reproductive and parental behaviors, brain sexual differentiation, ingestive behaviors, circadian activity rhythms, pain, stress-related behaviors, and the neurobiology of reward. A strong emphasis is placed on understanding and interpreting relevant articles from the scientific literature.

Summary

MOLECULAR BIOLOGY II Title

NayaProfessorNotes

TBAText(s)

Two midterms, final, discussion participationGrading

Prereq BI 552, recommended BI/CH 421/422

1:00-2:005:00-6:00

DISCUSSION

CAS BI 553Course #

Fundamental mechanisms of gene regulation with emphasis on eukaryotes. Topics covered include levels of gene regulation focusing on transcription and post-transcriptional control, microRNAs, genome organization, and chromatin structure. Other topics include DNA recombination, signal transduction, mouse molecular genetics and stem cells.

Summary

NEUROENDOCRINOLOGY Title

G. CallardProfessorALSO OFFERED AS NE 554NotesA1 T 1:00-3:00, R 1:00-2:00Lecture Times

1) Nelson R.J., Sinauer. 2005.An Introduction to Behavioral Endocrinology. 4th Edition 2) Primary Research reports (var. scientific journals)

Text(s)

One hourly exam; one oral critique, either a final written research proposal or final exam; and class participation.

Grading

Prereq BI 315, or BI 325, or BI 425 or equivalent.

R 2:00-3:00

DISCUSSION:

CAS BI 554Course #

To study interactions between the two major integrative organ systems of vertebrates, the endocrine and nervous systems, in mediating environmental change and in controlling physiological and behavioral aspects of reproduction; development and growth; energy and water balance; and biological rhythms. Topics include neurohormonal control mechanisms at the cellular and molecular levels as well as the physiological consequences of neuroendocrine regulation in whole animal systems.

Summary

CARCINOGENESISTitle

GilmoreProfessorINDEPENDENT. STUDENTS WILL NOT RECEIVE CREDIT FOR THIS COURSE IF CAS BI 327 OR GMS BT 520 HAVE ALREADY BEEN TAKEN. NotesA1 MW 3:00-5:00Lecture Times

Weinberg (2013). The Biology of Cancer .Garland Science.Text(s)

Two exams, presentation, participationGrading

Prereq BI 203, BI 206, BI 552

CAS BI 576Course #

The course covers multiple aspects of cancer biology with a focus on molecular mechanisms underlying cancer development and progression, and the implications for therapy. Topics include oncogenes, tumor suppressors, ҈apoptosis, angiogenesis, metastasis, mouse models, and chemotherapy. Emphasis on current research.

Summary

SEMINAR IN BIOLOGY: NeurodegenerationTitle

HoProfessor2 CREDITSNotesF 10:00-12:00Lecture Times

Based on readings from research articles.Text(s)

Grading

Prereq Consent of instructor

Discussion/Lab Times H1

CAS BI 582Course #

Open to seniors and graduate students concentrating in neurobiology. Informal discussion on neurodegeneration based on intensive study of the literature.

Summary

SEMINAR IN BIOLOGY: Latitudinal Gradient in Species DiversityTitle

MullenProfessor2 CREDITS NotesArranged Lecture Times

Based on readings from research articles.Text(s)

Attendance 25%, Presentation 50%, Review Paper 25%Grading

Prereq Consent of instructor

CAS BI 582Course #

The latitudinal gradient in species diversity is one of the most striking biogeographic patterns in nature, with species richness peaking in equatorial regions for nearly all groups. Despite considerable effort to understand the origin and maintenance of latitudinal gradients in species diversity, a multitude of potentially interacting, non mutually exclusive hypotheses exist, and no single over-riding explanation has emerged. However multiple hypothese link the latitudinal diversitty gradient to a presumed gradient in the strength of biotic interactions between temperate and tropical environments. While biotic interactions are believed to play a major role in the origin and maintenance of diversity and may drive increased rates of adaption and speciation in tropical regions, this hypothesis remains virtually untested. This course will explore the primary literature dealing with causes and consequences of latitudinal clines in species richness. Students can expect to gain experience with modern approaches in tropical ecology, evolutionary biology and phylogenetic hypothesis testing.

Summary

PHYSIOLOGY OF THE SYNAPSETitle

ManProfessorNotes

A1 F 10:00-12:00Lecture Times

TBAText(s)

Midterm exam; final exam, class presentation/ participation Grading

Prereq CAS BI 325 & CAS BI 481; OR CAS BI 445

A1 M 10:00-12:00

DISCUSSION:

CAS BI 599 Course #

Structure, function, and composition of synapses in the nervous system.Topics include transmitter release and uptake, synaptogenesis and plasticity as cellular basis for higher brain functions such as learning and memory. Emphasis on critical readings from primary literature.

Summary

spring

METROPOLITAN COLLEGE

wBI 106 HUMAN ANATOMY LEC C1 W 6:00-9:00PMProf. Greenwald LAB B4 T 6:00-8:00PM

LAB D1 R 6:00-8:00PM

BI 108 BIOLOGY II LEC A1 M 6:00-9:00PMProf. Heisermann LAB C1 W 6:00-9:00PM

BI 206 GENETICS (CM) LEC B1 TR 6:00-7:30PMStaff DIS T 7:30-8:30PM

BI 303 ECOLOGY (EBE) LEC A1 M 6:00-9:00PMProf. Wasserman LAB C1 W 6:00-9:00PM

BI 315 SYSTEMS PHYSIOLOGY (PN) LEC A1 M 6:00-9:00PMProf. Vyshedskiy LAB C1 W 6:00-9:00PM

BI 491/492 RESEARCH IN BIOLOGY DRS A1 ArrangedArranged

wNOT FOR BIOLOGY CONCENTRATION CREDIT

Title HONORS RESEARCH IN BMB - Boston University · 2014-01-13 · Title HUMAN INFECTIOUS DISEASE:...

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Transcript of Title HONORS RESEARCH IN BMB - Boston University · 2014-01-13 · Title HUMAN INFECTIOUS DISEASE:...

WillmsNelson BMB 2008 postprint - The Atrium

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