Agnes Scott CollegeAgnes Scott CollegeDepartment of ChemistryDepartment of Chemistry

(an American Chemical Society approved program)(an American Chemical Society approved program)Program in Biochemistry and Molecular Biology (BMB)Program in Biochemistry and Molecular Biology (BMB)

Why Major in Chemistry or BMB?Why Major in Chemistry or BMB?

Career OpportunitiesCareer Opportunities Research (industry, biomedical fields)Research (industry, biomedical fields) Academic chemist (biomedical, biological)Academic chemist (biomedical, biological) Medical schoolMedical school

MDMD MD/PhDMD/PhD

Teaching (MAT)Teaching (MAT) Law school Law school Library scienceLibrary science

What do our majors do?What do our majors do? Sara B. – second year graduate student at Sara B. – second year graduate student at

Northwestern UniversityNorthwestern University DeeDee S. – third year graduate student at DeeDee S. – third year graduate student at

Northwestern UniversityNorthwestern University Patrice B. – 2003, Ph.D. Purdue University, Dreyfus Patrice B. – 2003, Ph.D. Purdue University, Dreyfus

Fellow, Ga. Instit. Tech. Fellow, Ga. Instit. Tech. Nina T. – Research Fellowship, CDCNina T. – Research Fellowship, CDC Abena F. – Rollin’s School of Public HealthAbena F. – Rollin’s School of Public Health Sara S. – CDC Fellowship in NamibiaSara S. – CDC Fellowship in Namibia Mary F. – 1Mary F. – 1stst year graduate student at Emory year graduate student at Emory

Chemistry FacultyChemistry Faculty Doug Fantz, Assistant ProfessorDoug Fantz, Assistant Professor

Biochemistry, organic chemistry, first year seminarBiochemistry, organic chemistry, first year seminar Lilia Harvey, Associate ProfessorLilia Harvey, Associate Professor

Organic chemistry, senior seminarOrganic chemistry, senior seminar Ruth Riter, Assistant ProfessorRuth Riter, Assistant Professor

Analytical chemistry, introductory chemistry, Analytical chemistry, introductory chemistry, quantitative analysis, environmental chemistryquantitative analysis, environmental chemistry

Leon Venable, Associate ProfessorLeon Venable, Associate Professor Introductory chemistry, bioinorganic chemistry, Introductory chemistry, bioinorganic chemistry,

advanced inorganic chemistryadvanced inorganic chemistry Patrice B., sabbatical replacement for 06-07Patrice B., sabbatical replacement for 06-07

Sara Winget, Visiting ProfessorSara Winget, Visiting Professor Physical chemistry, introductory chemistry Physical chemistry, introductory chemistry

Courses of StudyCourses of Study

Regular Chemistry MajorRegular Chemistry Major ACS (American Chemical Society) ACS (American Chemical Society)

Approved Chemistry MajorApproved Chemistry Major Chemistry MinorChemistry Minor Biochemistry & Molecular Biology Biochemistry & Molecular Biology (interdisciplinary major with biology)(interdisciplinary major with biology)

Chemistry Chemistry CurriculumCurriculum

non-ACS degreeClass Description Hours Non-Chem Pre/corequisites

101/101L Matter and Rxns 4

102/102L Periodicity 4

201/201L Organic I 4

202/202L Organic II 4

301/301L P. Chem. I 4 Math 118,119,220(R); Physics 110,111

302 P. Chem. II 4

311 Quant. Chem. Anal. 4

312 Instrumental 4 Physics 242,243 (electronics (2 hr each))

342L/343L Phys. and Inst. Meth. 1/1

431/L Mod. Inorg. 4

Variable Any advanced chem. 4

Total Hours 42 Total hours w/ prereqs 62 ; 66(R)

ACS certified degree-addition of Biochem. I

Minor 2 courses beyond 202

BMB CurriculumBMB CurriculumBiology Chemistry

BIO 191 : Molecular and Cellular Biology CHE 101/101L : Fund. Concepts of Matter and Reactions

BIO 192 : Genetics and Developmental Biology CHE 102/102L : Periodicity and Chemical Reactions

BIO 316 : Molecular Biology CHE 201/201L : Organic Chemistry I

BIO 300 / CHE 300* : Biochemistry I CHE 202/202L : Organic Chemistry II

CHE 300 / BIO 300* : Biochemistry I

plus one of the following BIO courses: CHE 301 : Physical Chemistry I

CHE 342L : Physical and Instrumental Methods of Exp. I CHE 400 : Biochemistry II

BIO 301 : Microbiology

BIO 309 : Cells and Tissues plus one of the following CHE courses:

BIO 315 : GeneticsBIO 317: Immunology

BIO 318 : Developmental Biology CHE 210 : Bio-inorganic Chemistry

CHE 302 : Physical Chemistry II

CHE 311 : Quantitative Chemical Analysis * Note: BIO 300 and CHE 300 are cross-listed courses, and either (but not both) can be taken to satisfy the major.** Note: CHE 301 requires MAT 118 & 119 as well as PHY 110 & 111.

Research Requirement

Course featuresCourse features

Small classesSmall classes Small labsSmall labs Labs are taught by Ph.D. chemistsLabs are taught by Ph.D. chemists Hands-on access to equipmentHands-on access to equipment Collaborative research opportunitiesCollaborative research opportunities

Research OpportunitiesResearch Opportunities Research with chemistry and biology Research with chemistry and biology

faculty membersfaculty members

Interdisciplinary research with faculty from Interdisciplinary research with faculty from other disciplinesother disciplines

Research collaborations (interdisciplinary Research collaborations (interdisciplinary or strictly chemical) with scientists at other or strictly chemical) with scientists at other institutionsinstitutions

Doug Fantz- BiochemistryDoug Fantz- Biochemistry

Investigation of the Investigation of the Ras pathway using Ras pathway using C. C. eleganselegans as a model as a model organismorganism

C. elegansC. eleganslin-3lin-3

let-23let-23

sem-5sem-5

let-60let-60

lin-45lin-45

mek-2mek-2

mpk-1mpk-1

lin-1lin-1

1˚ vulval fates1˚ vulval fates

H. sapiensH. sapiensEGFEGF

EGFREGFR

GRB2GRB2

RASRAS

RAFRAF

MAPKKMAPKK

MAPKMAPK

Elk-1Elk-1

proliferationproliferation

Lilia Harvey – Organic ChemistryPhotochemistry of Alpha-(Aryloxy) Acetophenone and Derivatives

O

O

O

O

CH3O

O

O

O

O

CH3O

O

O

O

O

O

O

O

O

CH3O

O

O

O

O

CH3O

O

O

O

O

O

O

O

O

CH3O

O

O

O

O

CH3O

O

O

O

O

Ruth E. Riter – Analytical ChemistryPhotoinduced Electron Transfer Across Reverse Micellar Interfaces

T. Leon Venable – Inorganic Chemistry(1)Synthesis and Characterization of Ru-B Clusters as Potential

Cancer Therapy Agents(2)Synthesis and Characterization of Cu-Amino Acid Complexes

Sarah Winget – Physical Chemistry - use of vibrational spectroscopy to design and

characterize surface and interface chemistries

SEM image from Zhao et al, International Journal of Nanoscience, 1, (2002) 87-97

New EquipmentNew Equipment

~ $750,000 worth of new equipment and ~ $750,000 worth of new equipment and equipment upgradesequipment upgrades

Spectroscopy: UV-VIS, FT-IR, Laser, Spectroscopy: UV-VIS, FT-IR, Laser, RamanRaman

Separatory/analytical: GC, GC/MS, HPLC, Separatory/analytical: GC, GC/MS, HPLC, CECE

Structural/analytical: NMR – 400 MHzStructural/analytical: NMR – 400 MHz Probe microscopy: STM/AFMProbe microscopy: STM/AFM Data acquisitionData acquisition

Scanning Tunneling Microscopy STM / Scanning Tunneling Microscopy STM / Atomic Force Microscopy AFMAtomic Force Microscopy AFM

2.5 Å

STM Image of Graphite Molecular Model of Graphite

NMRNMRNuclear Magnetic Nuclear Magnetic ResonanceResonance– Same process as Same process as

used in MRI (Magnetic used in MRI (Magnetic Resonance Imaging)Resonance Imaging)

400 MHz400 MHz– Greater sensitivityGreater sensitivity– Can study proteinsCan study proteins– Other resonances Other resonances

C-13, B-11, P-31, etc.C-13, B-11, P-31, etc.

Student Affiliates of the American Student Affiliates of the American Chemical SocietyChemical Society

Active student chemistry organizationActive student chemistry organization Four-time national award winners for Four-time national award winners for

chapter activitieschapter activities Outreach activitiesOutreach activities

TutoringTutoring Chemistry shows & demonstrationsChemistry shows & demonstrations

Campus open-house activitiesCampus open-house activities

Questions?Questions?

Dr. Douglas FantzDr. Douglas Fantz SC301WSC301W x-5067x-5067 dfantz@agnesscott.edudfantz@agnesscott.edu