Epidemiologic Transition Mortality Rates Infectious Diseases NCD.

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Epidemiologic Transition

Mor

tali

ty R

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Infectious Diseases

NCD

Death Rates for TB in England Death Rates for TB in England and Walesand Wales

0

500

1000

1500

2000

2500

3000

3500

4000

4500

1840 1855 1875 1895 1915 1935 1948 1958 1968

Death Rates for TB in England Death Rates for TB in England and Walesand Wales

0

500

1000

1500

2000

2500

3000

3500

4000

4500

1840 1855 1875 1895 1915 1935 1948 1958 1968

TB Bacillus Identified

Chemotherapy

BCG Vaccination

Death Rates for Measles in Death Rates for Measles in Children in England and WalesChildren in England and Wales

0

200

400

600

800

1000

1200

1400

1850 1870 1890 1910 1930 1950 1970

Death Rates for Measles in Death Rates for Measles in Children in England and WalesChildren in England and Wales

0

200

400

600

800

1000

1200

1400

1850 1870 1890 1910 1930 1950 1970

Immunization begun

Epidemiologic Transition

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CA

CHDNIDDM

Trauma

CHD Death RatesCHD Death RatesMales, aged 45-54Males, aged 45-54

0 500 1000 1500

Thailand

Guatamala

Japan

Egypt

Italy

Bulgaria

US

UK

Scotland

Finland

Incidence of Stomach CAIncidence of Stomach CAMalesMales

0 20 40 60 80 100

Nigeria

India

US White

US NW

UK

Finland

Iceland

Columbia

Japan

Breast Cancer IncidenceBreast Cancer IncidenceFemalesFemales

0 5 10 15 20 25 30

Japan

Nigeria

Brazil

Singapore

Jamaica

Poland

UK

US NW

US Whites

Cirrhosis Death Rates,Cirrhosis Death Rates,Males, aged 45-54Males, aged 45-54

0 10 20 30 40 50 60 70 80 90

UK

Scotland

Hong Kong

US

Japan

Italy

France

Death Rates for StrokeDeath Rates for StrokeMales, aged 45-54Males, aged 45-54

0 10 20 30 40 50 60 70 80

Egypt

US

Thailand

UK

Italy

Scotland

Finland

Japan

High Incidence of NCDs in High Incidence of NCDs in Developed CountriesDeveloped Countries

CardiovascularCardiovascular

CHDCHD

Deep Vein ThrombosisDeep Vein Thrombosis RespiratoryRespiratory

EmphysemsEmphysems

Lung CALung CA Female GenitalFemale Genital

EndometriosisEndometriosis

Endometrial CAEndometrial CA

High Incidence of NCDs in High Incidence of NCDs in Developed CountriesDeveloped Countries

BreastBreast

Breast CABreast CA

Fibrocystic DiseaseFibrocystic Disease Male GenitalMale Genital

Prostrate CAProstrate CA

MetabolicMetabolic NIDDMNIDDM

High Incidence of NCDs in High Incidence of NCDs in Developing CountriesDeveloping Countries

Possible Infectious EtiologyPossible Infectious Etiology

Macronodular CirrhosisMacronodular Cirrhosis

Hepatocellular CarcinomaHepatocellular Carcinoma

Rheumatic Heart DiseaseRheumatic Heart Disease

Iron deficiency anemiaIron deficiency anemia Related to Nutrition DeficiencyRelated to Nutrition Deficiency

Endemic GoiterEndemic Goiter

Malnutrition Related Diabetes.Malnutrition Related Diabetes.

Back to NatureBack to Nature

Improved Physical activityImproved Physical activity A Healthier Diet, less saturated A Healthier Diet, less saturated

fats, more fiberfats, more fiber Less StressLess Stress

TransitionTransition

NomadsNomads FarmersFarmers UrbanUrban

45 yrs45 yrs

60 yrs60 yrs

70 yrs70 yrs

1960

Urban Rural

USA DevelopingCountries

rural urban

2003

Urban Rural

USA DevelopingCountries

ruralurban

Life Expectancy in Developing Life Expectancy in Developing CountriesCountries

0

10

20

30

40

50

60

70

1950 1975 1985 1995

Changing Life ExpectanciesChanging Life Expectancies

0

10

20

30

40

50

60

70

Africa India Latin America

1950

1990

Causes of DeathCauses of Death

Age 15-44Age 15-44 AccidentsAccidents

CACA

CHDCHD

Age 45-54Age 45-54 CHDCHD

CACA

AccidentsAccidents

Age 15-44Age 15-44 AccidentsAccidents

CHDCHD

CACA

Age 45-54Age 45-54 CHDCHD

CACA

AccidentsAccidents

Developed Developing

Other TransitionsOther Transitions

AgricultureAgriculture ForestryForestry ToxicityToxicity UrbanizationUrbanization Fossil FuelFossil Fuel

NutritionNutrition

Systems AnalysisSystems Analysis

Attempts to build a replica of the real Attempts to build a replica of the real world and experiment with it in order world and experiment with it in order

to obtain a better understanding of to obtain a better understanding of what is observedwhat is observed

Systems approachSystems approach

The Need for the Development of a The Need for the Development of a systems approach to Epidemiologysystems approach to Epidemiology

EPI systemsEPI systems

Interplay of factors that cause one disease Interplay of factors that cause one disease to increase while another falls.to increase while another falls.