Supplementary Files
Supplementary file 1. Forest plot for the association between moderate versus low
leisure time physical activity and the relative risk of fatal or non-fatal stroke
(hemorrhagic or ischemic) using the IVhet model. The black squares represent the log
scale relative risks (In RR) while the left and right extremes of the squares represent
the corresponding 95% confidence intervals for the In RR. The middle of the black
diamonds represent the In RR while the right and left extremes of the diamond
represent the corresponding 95% confidence intervals.
Supplementary file 2. Doi plot of overall results for moderate versus low leisure time
physical activity.
Supplementary file 3. Influence analysis plot of overall results for moderate versus
low leisure time physical activity with each study deleted from the model once and
ranked from largest to smallest reductions in the overall RR.
Supplementary file 4. Influence analysis plot (log scale) of overall results for moderate
versus low leisure time physical activity with each study deleted from the model once
and ranked from largest to smallest reductions in the overall RR.
Supplementary file 5. Cumulative meta-analysis, ranked by year, of overall RR results
for moderate versus low leisure time physical activity.
Supplementary file 6. Cumulative meta-analysis, ranked by year, of overall RR (log
scale) results for moderate versus low leisure time physical activity.
Supplementary file 7. Forest plot for the association between high versus low leisure
time physical activity and the relative risk of fatal or non-fatal stroke (hemorrhagic or
ischemic) using the IVhet model. The black squares represent the log scale relative
risks (In RR) while the left and right extremes of the squares represent the
corresponding 95% confidence intervals for the In RR. The middle of the black
diamonds represent the In RR while the right and left extremes of the diamond
represent the corresponding 95% confidence intervals.
Supplementary file 8. Doi plot of overall results for high versus low leisure time
physical activity.
Supplementary file 9. Influence analysis of overall results for high versus low leisure
time physical activity with each study deleted from the model and ranked from largest
to smallest reductions in the overall RR.
Supplementary file 10. Influence analysis of overall results for high versus low leisure
time physical activity with each study deleted from the model once and ranked from
largest to smallest reductions in the overall RR on the log scale.
Supplementary file 11. Cumulative meta-analysis, ranked by year, of overall RR
results for high versus low leisure time physical activity.
Supplementary file 12. Cumulative meta-analysis, ranked by year, of overall RR (log
scale) results for high versus low leisure time physical activity.
Supplementary file 1
Supplementary file 2
LFK index: -3.44 (Major asymmetry)
ln RR0-0.273-0.547
|Z
-score|
2.665
2.132
1.599
1.066
0.533
Supplementary file 3
Supplementary file 4
Supplementary file 5
RR1.51.20.90.60.3
Study Wannamethee et al., 1992
Kiely et al., 1994 (a)
Lee et al., 1998 Lee et al., 1999 Hu et al., 2000
Hu et al., 2005 (a)
Williams et al., 2009 (b) Williams et al., 2009 (a)
Myint et al., 2006 (b) Myint et al, 2006 (a)
Sattelmair et al., 2010
Hu et al., 2005 (b)
Kiely et al., 1994 (b)
RR (95% CI) 0.60 ( 0.22, 1.64) 0.64 ( 0.44, 0.95)
0.72 ( 0.49, 1.06) 0.77 ( 0.58, 1.01) 0.78 ( 0.63, 0.96) 0.82 ( 0.69, 0.96)
0.82 ( 0.74, 0.92) 0.83 ( 0.75, 0.92) 0.83 ( 0.76, 0.91) 0.83 ( 0.75, 0.92)
0.83 ( 0.75, 0.93)
0.84 ( 0.75, 0.93)
0.86 ( 0.56, 1.30)
Supplementary file 6
Supplementary file 7
Supplementary file 8
LFK index: -3.00 (Major asymmetry)
ln RR0-0.553-1.105
|Z
-score|
3.5
3
2.5
2
1.5
1
0.5
0
Supplementary file 9
Supplementary file 10
RR2.521.510.50
Study Wannamethee et al., 1992
Kiely et al., 1994 (a)
Williams et al., 2009 (b) Williams et al., 2009 (a)
Sattelmair et al., 2010
Myint et al, 2006 (a) Myint et al., 2006 (b)
Hu et al., 2005 (a) Hu et al., 2005 (b)
Hu et al., 2000
Kiely et al., 1994 (b) Lee et al., 1998 Lee et al., 1999
RR (95% CI) 0.20 ( 0.02, 2.45) 0.66 ( 0.45, 0.97)
0.73 ( 0.65, 0.83) 0.74 ( 0.66, 0.83)
0.75 ( 0.67, 0.84)
0.75 ( 0.68, 0.83) 0.75 ( 0.68, 0.83)
0.76 ( 0.68, 0.86) 0.76 ( 0.69, 0.85)
0.79 ( 0.68, 0.92)
0.80 ( 0.52, 1.24) 0.81 ( 0.64, 1.02) 0.83 ( 0.70, 0.99)
Supplementary file 11
Supplementary file 12
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