Supplementary Files Supplementary file 1. Forest plot for the...

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Supplementary Files Supplementary file 1. Forest plot for the association between moderate versus low leisure time physical activity and the relative risk of fatal or non-fatal stroke (hemorrhagic or ischemic) using the IVhet model. The black squares represent the log scale relative risks (In RR) while the left and right extremes of the squares represent the corresponding 95% confidence intervals for the In RR. The middle of the black diamonds represent the In RR while the right and left extremes of the diamond represent the corresponding 95% confidence intervals. Supplementary file 2. Doi plot of overall results for moderate versus low leisure time physical activity. Supplementary file 3. Influence analysis plot of overall results for moderate versus low leisure time physical activity with each study deleted from the model once and ranked from largest to smallest reductions in the overall RR. Supplementary file 4. Influence analysis plot (log scale) of overall results for moderate versus low leisure time physical activity with each study deleted from the model once and ranked from largest to smallest reductions in the overall RR. Supplementary file 5. Cumulative meta-analysis, ranked by year, of overall RR results for moderate versus low leisure time physical activity. Supplementary file 6. Cumulative meta-analysis, ranked by year, of overall RR (log scale) results for moderate versus low leisure time physical activity.

Transcript of Supplementary Files Supplementary file 1. Forest plot for the...

  • Supplementary Files

    Supplementary file 1. Forest plot for the association between moderate versus low

    leisure time physical activity and the relative risk of fatal or non-fatal stroke

    (hemorrhagic or ischemic) using the IVhet model. The black squares represent the log

    scale relative risks (In RR) while the left and right extremes of the squares represent

    the corresponding 95% confidence intervals for the In RR. The middle of the black

    diamonds represent the In RR while the right and left extremes of the diamond

    represent the corresponding 95% confidence intervals.

    Supplementary file 2. Doi plot of overall results for moderate versus low leisure time

    physical activity.

    Supplementary file 3. Influence analysis plot of overall results for moderate versus

    low leisure time physical activity with each study deleted from the model once and

    ranked from largest to smallest reductions in the overall RR.

    Supplementary file 4. Influence analysis plot (log scale) of overall results for moderate

    versus low leisure time physical activity with each study deleted from the model once

    and ranked from largest to smallest reductions in the overall RR.

    Supplementary file 5. Cumulative meta-analysis, ranked by year, of overall RR results

    for moderate versus low leisure time physical activity.

    Supplementary file 6. Cumulative meta-analysis, ranked by year, of overall RR (log

    scale) results for moderate versus low leisure time physical activity.

  • Supplementary file 7. Forest plot for the association between high versus low leisure

    time physical activity and the relative risk of fatal or non-fatal stroke (hemorrhagic or

    ischemic) using the IVhet model. The black squares represent the log scale relative

    risks (In RR) while the left and right extremes of the squares represent the

    corresponding 95% confidence intervals for the In RR. The middle of the black

    diamonds represent the In RR while the right and left extremes of the diamond

    represent the corresponding 95% confidence intervals.

    Supplementary file 8. Doi plot of overall results for high versus low leisure time

    physical activity.

    Supplementary file 9. Influence analysis of overall results for high versus low leisure

    time physical activity with each study deleted from the model and ranked from largest

    to smallest reductions in the overall RR.

    Supplementary file 10. Influence analysis of overall results for high versus low leisure

    time physical activity with each study deleted from the model once and ranked from

    largest to smallest reductions in the overall RR on the log scale.

    Supplementary file 11. Cumulative meta-analysis, ranked by year, of overall RR

    results for high versus low leisure time physical activity.

    Supplementary file 12. Cumulative meta-analysis, ranked by year, of overall RR (log

    scale) results for high versus low leisure time physical activity.

  • Supplementary file 1

  • Supplementary file 2

    LFK index: -3.44 (Major asymmetry)

    ln RR0-0.273-0.547

    |Z

    -score|

    2.665

    2.132

    1.599

    1.066

    0.533

  • Supplementary file 3

  • Supplementary file 4

  • Supplementary file 5

    RR1.51.20.90.60.3

    Study Wannamethee et al., 1992

    Kiely et al., 1994 (a)

    Lee et al., 1998 Lee et al., 1999 Hu et al., 2000

    Hu et al., 2005 (a)

    Williams et al., 2009 (b) Williams et al., 2009 (a)

    Myint et al., 2006 (b) Myint et al, 2006 (a)

    Sattelmair et al., 2010

    Hu et al., 2005 (b)

    Kiely et al., 1994 (b)

    RR (95% CI) 0.60 ( 0.22, 1.64) 0.64 ( 0.44, 0.95)

    0.72 ( 0.49, 1.06) 0.77 ( 0.58, 1.01) 0.78 ( 0.63, 0.96) 0.82 ( 0.69, 0.96)

    0.82 ( 0.74, 0.92) 0.83 ( 0.75, 0.92) 0.83 ( 0.76, 0.91) 0.83 ( 0.75, 0.92)

    0.83 ( 0.75, 0.93)

    0.84 ( 0.75, 0.93)

    0.86 ( 0.56, 1.30)

  • Supplementary file 6

  • Supplementary file 7

  • Supplementary file 8

    LFK index: -3.00 (Major asymmetry)

    ln RR0-0.553-1.105

    |Z

    -score|

    3.5

    3

    2.5

    2

    1.5

    1

    0.5

    0

  • Supplementary file 9

  • Supplementary file 10

  • RR2.521.510.50

    Study Wannamethee et al., 1992

    Kiely et al., 1994 (a)

    Williams et al., 2009 (b) Williams et al., 2009 (a)

    Sattelmair et al., 2010

    Myint et al, 2006 (a) Myint et al., 2006 (b)

    Hu et al., 2005 (a) Hu et al., 2005 (b)

    Hu et al., 2000

    Kiely et al., 1994 (b) Lee et al., 1998 Lee et al., 1999

    RR (95% CI) 0.20 ( 0.02, 2.45) 0.66 ( 0.45, 0.97)

    0.73 ( 0.65, 0.83) 0.74 ( 0.66, 0.83)

    0.75 ( 0.67, 0.84)

    0.75 ( 0.68, 0.83) 0.75 ( 0.68, 0.83)

    0.76 ( 0.68, 0.86) 0.76 ( 0.69, 0.85)

    0.79 ( 0.68, 0.92)

    0.80 ( 0.52, 1.24) 0.81 ( 0.64, 1.02) 0.83 ( 0.70, 0.99)

    Supplementary file 11

  • Supplementary file 12


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