Download - European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Transcript
Page 1: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

European Meningococcal Epidemiology in Real Time

(EMERT II)

Keith Jolley

Page 2: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT facilitates sharing of molecular typing information among reference laboratories

Page 3: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT was established nearly 10 years ago

Page 4: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT reports circulating clonal complex and fine-typing data to participating laboratories

Page 5: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Entering the genomic era

• EMERT-II will be incorporated in to the PubMLST Neisseria database

• Data can be optionally made public

• Submitters can edit

• Minimal or extensive data can be uploaded

serogroup finetyping MLST whole genome

Page 6: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Use standard BIGSdb tools on EMERT data

Page 7: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT II will facilitate reporting of summary data to TESSy

genomes

Single gene results

EMERT II

PubMLST Clonal complex Fine-type (on demand via RESTful API)

TESSy

common identifier

Page 8: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Common user accounts across PubMLST

PubMLST Web server

Neisseria

seqdef isolates

seqdef isolates

seqdef isolates

Haemophilus influenzae Streptococcus

pneumoniae

Page 9: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Common user accounts across PubMLST

PubMLST Web server

Neisseria

seqdef isolates

seqdef isolates

seqdef isolates

Haemophilus influenzae Streptococcus

pneumoniae

User database

Page 10: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Acknowledgements

Martin Maiden

Ulrich Vogel Arie van der Ende Mathew Diggle