European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library...

10
European Meningococcal Epidemiology in Real Time (EMERT II) Keith Jolley

Transcript of European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library...

Page 1: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

European Meningococcal Epidemiology in Real Time

(EMERT II)

Keith Jolley

Page 2: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT facilitates sharing of molecular typing information among reference laboratories

Page 3: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT was established nearly 10 years ago

Page 4: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT reports circulating clonal complex and fine-typing data to participating laboratories

Page 5: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Entering the genomic era

• EMERT-II will be incorporated in to the PubMLST Neisseria database

• Data can be optionally made public

• Submitters can edit

• Minimal or extensive data can be uploaded

serogroup finetyping MLST whole genome

Page 6: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Use standard BIGSdb tools on EMERT data

Page 7: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

EMERT II will facilitate reporting of summary data to TESSy

genomes

Single gene results

EMERT II

PubMLST Clonal complex Fine-type (on demand via RESTful API)

TESSy

common identifier

Page 8: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Common user accounts across PubMLST

PubMLST Web server

Neisseria

seqdef isolates

seqdef isolates

seqdef isolates

Haemophilus influenzae Streptococcus

pneumoniae

Page 9: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Common user accounts across PubMLST

PubMLST Web server

Neisseria

seqdef isolates

seqdef isolates

seqdef isolates

Haemophilus influenzae Streptococcus

pneumoniae

User database

Page 10: European Meningococcal Epidemiology in Real Time (EMERT II)...the MRF Meningococcus Genome Library is here. Status Sequence database sequences: 861835 Profiles: MLST: 12486 rpIF species:

Acknowledgements

Martin Maiden

Ulrich Vogel Arie van der Ende Mathew Diggle