Transport of Oxygen in Blood and Tissue Fluids

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    Transport of Oxygenin Blood and tissue

    uidsDR AMNA TAHIR

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    DIFFUSION OF O!"#N FROM TH# A$%#O$ITO TH# &U$MONAR! 'A&I$$AR! B$OOD

    • PO2 Of gaseous oxygen in the alveoli =

    104 mm Hg

    • PO2 Of venous blood entering the

    pulmonary capillary at its arterial end =40mm Hg

    • Initial pressure dierence= 104!40=

    "4mm Hg• PO2 Of the blood rises to that of

    alveolar air by the time the blood hasmoved a third of the distance throughthe capillary

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    #p ta$e of oxygenby the pulmonary

    blood

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     &'()*PO'& O+ O,-%.) I) &H.

    ('&.'I(/ /OO

    • 3 O+ the blood that enters theleft atrium 5ith PO

    2= 104 mmHg

    2 O+ the blood has passed thebronchial circulation 6 *H#)&./OO7 5ith PO

    2=40 mmHg

    8enous admixture of blood• PO2 of the blood pumped by

    aorta = 9 mmHg

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    DIFFUSION OF O!"#N FROMTH# RI&H#RA$ 'A&I$$ARI#S

    INTO TH# TISSU# F$UID• PO2 at the arterial end= 9

    mmHg

    PO2 in the interstitial :uid thatsurround the tissue cells= 40mmHg

    •  &issue PO2 is determined by 2

    factors1; 'ate of oxygen transport to

    tissues in the blood

    2; &he rate at 5hich the oxygen is

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    DIFFUSION OF O!"#N FROM TH# RI&H#RA$'A&I$$ARI#S TO TH# TISSU# '#$$S

    •  Intracellular PO2 ranges 9!40

    mmHg

    (verage 2< mmHg• 1!< mmHg is reuired

    • /arger safety factor

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    'O/. O+ H.>O%/OI) I) O,-%.)

     &'()*PO'&

    • ? is carried in chemicalcombination 5ith Hb

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