The Acquired Immune System

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    THE IMMUNE SYSTEM

    The Acquired System

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    The Immune System

    Acquired Immunity

    B-Cell Immunity

    Consist of B-cells

    Matures in the

    Bone Marrow

    Produce Anti-Bodies

    involved with

    Primary and

    Secondary response

    Anti-Body in the making!

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    The Immune System

    Anti-Bodies

    Germ goes here

    Specific anti-bodies are

    produced against specific

    antigens

    Made by B-Cells

    They neutralize and

    inactivate germs.

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    The Immune System

    Primary and Secondary Responses

    First Flu infection Second Flu infection

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    The Immune System

    Innate Immunity Acquired Immunity

    Resistance of skin Destruction of organisms

    by the acids in the

    stomach

    Chemical compounds in

    the blood

    Cells called

    Macrophages that

    ingest foreign objects

    B-Cell Immunity T-Cell Immunity

    Consist of B-cells

    Produce Anti-Bodies

    involved with

    Primary and

    Secondary response

    Consists of T-Cells

    T-Cells are:

    T helper cells

    T killer cells

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    HIV

    The Life cycle of HIV

    Fusion Binding to the host cell

    Reverse Transcription incorporate HIVs genetic

    material into DNAIntegration integrate the DNA of HIV with the DNA of

    the host cell

    Transcription a new strand of HIV genetic material is

    made

    Translation All the building blocks for a new virus are

    gatheredAssembly The blocks are put together to form a new

    HIV

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    HIV

    CD4+ Count:

    When your CD4+ count drops below

    350 CD4+ cells/mm, they start with

    ARV therapy

    To measure the total CD4+ cells/mm in your blood.

    It is an indicator of the strength of your immune system.

    A normal man has between 500-1200CD4+ cells/mm

    A low CD4+ count means a high viral

    load in the blood