TAMU Conacyt Magazine Final

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A LIANZAS Texas A&M University - CONACyT: Collaborative Research Grant Program 2007 en Investigación Diabetes detection medical technology undergoing clinical trials in Mexico.

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Alianzas en Investigacion, Texas A&M University - CONACYT

Transcript of TAMU Conacyt Magazine Final

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A L I A N Z A STexas A&M University - CONACyT: Collaborative Research Grant Program • 2007

en Investigación

Diabetes detection medical technology undergoing clinical trials in Mexico.

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Welcome to ALIANZAS en Investigación, which highlights the successes of the research alliance between Texas A&M University and Mexico’s Consejo Nacional de Ciencia y Tecnologia (CONACyT). The Texas A&M University-CONACyT: Collaborative Research Grant Program marks a significant place in the strong history between a Texas university with a commitment to others and a Mexican government body with much of the same goals – improve lives, ensure economic stability and make a difference for the future.

The original grant program spans five years. Those five years have been marked with numerous successes that have truly changed lives in Mexico and Texas. This publication is a celebration to mark the progress the two friends have had, and I am very pleased to share these stories.

In 2000, officials signed detailed documents, reviewers polished contracts, and photos marked the occasion. But the real work and fun was yet to come. The vision of the Texas A&M–CONACyT: Collaborative Research Grant Program was just beginning, but the leaders of research at Texas A&M and CONACyT knew the possibilities. Researchers were given the opportunity to work with each other across the border. They applied for grants up to $24,000 to seed their research and make it grow. The first year many researchers applied; each team with at least one Texas A&M researcher and one CONACyT researcher. From that group, 15 grants were awarded. Congratulations were offered, and the work began.

The first year everyone learned a great deal about the process and ways to improve. The researchers offered feedback, and the program grew stronger. From that first year, proposals have improved and the competition has increased. This year 17 teams were awarded to bring the total of awards to 78 for the life of the agreement. You can see a list of all of the awards given during the program in the back of this publication.

Each year, the program sees new faces and some familiar ones. Each time with a focus on the future and improving research within Texas and Mexico. Some may call it a romantic notion to believe that their work will make a difference, but it can be called true in the case of this grant program. I look forward to the continuation of the program and the future successes. Thank you for spending time learning about how Texas A&M and CONACyT are working to accomplish new and exciting futures in research for both countries.

Sincerely,

Richard E. EwingVice President for ResearchTexas A&M University

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The CONACyT Continuum

Diabetes Detection aided by Digital Imaging

The Best of Both Worlds 10Altered States12Cave Men14Forging Futures for

Fishes18Grant Award

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Vol. 1, No. 1

ALIANZAS en Investigación is published by the Office of the Vice President for Research at Texas A&M University to highlight the breadth and depth of research being conducted through the Texas A&M University-CONACyT: Collaborative Research Grant Program. Integra, the font used in this publication was designed by Gabriel Martinez Meave, type designer and director of the Kimera Typefoundry/Mexico. Cover image credit: Michael Brown/Shutterstock Images.

Julia K. BarkerAssistant Vice President for Research312 Jack K. Williams Administration BuildingTexas A&M UniversityCollege Station, Texas [email protected]

Victor Gabriel FernandezConsejo Nacional de Ciencia y TechnologiaAv. Constituyentes 1046, Col. Lomas AltasC.P.: 11950, Mexico, [email protected]

Editor ................... Tiffany Inbody

Designer ...................Susan Wolff

Writers ...................Mike Downey Vicky Sexton Holder Kara Bounds Socol

http://conacyt.tamu.edu979.845.8585

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CONACyTGrants serve as catalysts for future research

by Kara Bounds Socol

Asthe recipient of Texas A&M-CONACyT grants in 2002, 2003 and 2004, Dr. L. Garry Adams has reason to be grateful for

the funding provided for his research. But even more importantly, he says, he is thankful for the lifelong relationships the grants continue to foster among researchers and graduate students at Texas A&M University and institutions in Mexico.

“It is those exchanges that forge strong research linkages that continue for years,” says Adams, professor of veterinary pathobiology and associate dean of research at Texas A&M’s College of Veterinary Medicine. “And when you work with graduate students together, those are lifelong bonds.”

Dr. José Angel Gutiérrez-Pabello, professor of bacteriology and mycology at the Universidad Nacional Autónoma de México, agrees.

In 2002, Gutiérrez-Pabello and Adams began a multiyear bovine tuberculosis project. A Texas A&M-CONACyT grant is not only allowing the researchers to look for a solution to a serious health problem but also enabling one of Gutiérrez-Pabello’s graduate students to work full-time on the project, which will involve research alongside Adams at Texas A&M.

Texas A&M-CONACyT grants therefore facilitate much more than an exchange of information: They encourage an actual physical exchange of scientists and graduate students. And those relationships create ties with other scientists and graduate students that multiply over time. As Adams puts it, “It’s a continuum of linkages of graduate education and research.”

Adams says the variety of Mexican researchers with whom he partners is determined by the organism he is researching. He considers the expertise of the scientist as well as the region where the organism is prevalent.

Adams’ 2003 Texas A&M-CONACyT grant, for instance, involved a research partnership with Dr. Ricardo Gomez-Flores, professor of immunology at the Universidad Autónoma de Nuevo León (UANL). Their project evaluated the fluorescence polarization assay (FPA) as a screening test for brucellosis in goats.

Brucellosis is a chronic, infectious disease that often leads to spontaneous abortions. Although brucellosis in livestock has been virtually eradicated in the United States, it is endemic and widely dispersed throughout Mexico.

Gomez-Flores says that in conventional tests used to detect brucellosis in goats, thousands of misdiagnosed animals are killed each year and millions of dollars are wasted. FPA screenings, which detect brucella antibodies quickly, accurately and cost-effectively, avoid that risk. The results from his and Adams’ Texas A&M-CONACyT research demonstrated the effectiveness of FPA on goats, he says. The two researchers are now investigating brucellosis detection in humans by using this same test.

“Thanks to this grant, we have significantly advanced in the field and published a manuscript,” Gomez-Flores says. “In addition, the experience from the grant helped a UANL Ph.D. student complete his academic and scientific credits and present two posters in Brucellosis International Research conferences.”

Adams and Gutiérrez-Pabello’s bovine tuberculosis project deals with a disease that affects both animal and human populations along the U.S.–Mexico border. The project Gutiérrez-Pabello is undertaking with Adams strives to both

The

Continuum

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better understand the origin and effects of the disease and develop a diagnostic tool to identify natural disease resistance in cattle. Specifically, the researchers and their graduate students are trying to find different patterns of gene expression among cattle that resist the disease and those that are susceptible to it.

“Bovine tuberculosis is a very prevalent disease in Mexico,” Gutiérrez-Pabello explains. “Our findings may add another tool to control it.”

Like his work with Gomez-Flores, Adams’ 2004 Texas A&M-CONACyT grant focused on brucellosis in goats. Adams partnered with Dr. Alberto Morales Loredo of Mexico’s National Institute of Forestry, Agricultural and Animal Research (INIFAP) and Instituto Tecnológica de Estudios Superiores Monterrey. The researchers are exploring a vaccine that would protect goats against both brucellosis and orf.

Adams says a specific benefit of working with researchers in Mexico is access to research subjects. At Texas A&M, he says, his laboratory is equipped to study a wide range of pathogens. But in Mexico, he has the opportunity to work with actual humans who suffer from the conditions he’s studying. Diagnostic tests are therefore generated in Mexico, he says, with instruments developed in the United States.

Adams stresses that he could not undertake these research projects without the experience and expertise of his Mexican counterparts. “There is no superior group or inferior group,” he says of the Texas A&M-CONACyT research. “This is a partnership.”

Adams hopes the relationships he and his graduate students have forged with researchers in Mexico will eventually result in the global eradication of both brucellosis and tuberculosis. Brucellosis is still prevalent in 120 countries, he says, whereas tuberculosis can be found in even more. It’s through these types of grants that researchers are encouraged to share their expertise and apply it to help those afflicted.

“We try to bring our research back down to the animal on the farm,” Adams says, “as well as to the people it affects.”

Lawrence Manning/CORBIS

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Detection

Diabetes

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Digital Imaging

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What

began in 2003 as collaborative basic research among computer science researchers in Mexico and Texas A&M University has vaulted to a diabetes detection medical technology already undergoing clinical trials in Mexico.

The digital imaging mechanism is a mobile screening system that aims to detect diabetic retinopathy through a simple, painless process. Diabetic retinopathy is a leading cause of blindness, according to Dr. Jyh-Charn (Steve) Liu. An associate professor in the Texas A&M computer science department, Liu specializes in real-time computing systems and computer-assisted medical information systems.

The rapid technology transfer from laboratory to the public is another solid example of the potential far-reaching value of unfettered basic research and how the benefits of basic research cannot always be measured by their immediate applications.

Three years ago, Liu had begun work with researchers in Mexico at the Centro de Investigación Científica de Educación Superior de Ensenada (CICESE), or the Ensenada Center for Higher Education Scientific Research.

Liu, Jesus Favela, Jorge E. Preciado Velasco and Robert Conte Galvan were looking at how to transfer university research into real-world computer systems in industry.

“We had targeted software systems and were proposing a broad view at large-scale database systems, with education and telemedicine being our main thrust,” Liu says.

His colleagues in Mexico were concentrating on telemedicine projects, specifically the need for computer-aided medical informational systems, Liu says. “I kept hearing about a diabetes epidemic in Mexico, and I began to connect the dots with my other ongoing research projects.”

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One particularly intriguing issue is diabetic retinopathy, which is characterized by damage to the tiny blood vessels (capillaries) that nourish the retina, the tissue at the back of the eye that captures light and relays information to the brain. Nearly half the people with known diabetes have some degree of diabetic retinopathy. These blood vessels are often affected by the high blood sugar levels associated with diabetes. Early detection and proper treatment of diabetic retinopathy can prevent blindness, but many patients are not timely diagnosed because of limited resources.

The research project that had started to look at fundamental computing issues now was being focused on a narrower real-world target application for diabetic retinopathy. His Texas A&M-CONACyT work with Jesus Favela, Preciado Velcasco and Conte Galvan had become a catalyst for this key opportunity, Liu says.

“I was impressed with their active research in telemedicine working within the constraints they had,” Liu says.

In addition to information from Mexico, Liu was learning about the diabetes epidemic from more than one quarter.

“I was hearing stories about diabetes from many of my colleagues, their relatives and friends — particularly about retinopathy,” Liu says.

Technology seemed to be the most effective method to manage this particular problem. Developing a remote screening mechanism for this diabetic retinopathy problem would be a “win–win situation for underserved communities,” Liu says.

This sort of medical technology would free up more time for physicians to focus on clinically significant cases, Liu says.

“With the right technology, scarce resources can be better utilized at reduced costs,” Liu says.

Now, Liu continues to focus his efforts on the telemedicine environment to enhance reliability and accuracy of methods to recognize diabetic retinopathy.

“If we could develop reliable algorithms to address this problem, we could make a significant

In addition to the Texas A&M-CONACyT basic research channeling his research efforts into a real-world solution, Liu points to his Faculty Abroad experience and a 2001 Advanced Technology Program (ATP) grant as being keys for opening the door to his diabetes work.

“My time in Mexico had a big impact,” Liu says. “It gave me a strong impression of the needs of the area.”

His ATP basic research grant on imagery data structures was coupled with work through the Brooks Army Medical Center on retina image analysis, all of which eventually led to the diabetes work.

“When you capture and close the subtle gaps between basic research and the real world, sometimes you can have a big impact,” Liu says.

Texas A&M Executive Vice President and Provost David Prior (seated) checks out the new lab’s equipment with the assistance of Dr. Steve Liu of Texas A&M’sComputer Science Department.

impact,” Liu says.A goal was technology

that was mature enough to be used for minimal screening to reliably detect basic symptoms of diabetic retinopathy, Liu says.

The breakthrough came when researchers were able to identify a distinct signature for diabetic retinopathy. They used an off-the-shelf retinal camera to take digital images of a patient’s eyes, and the computer software would detect diabetic retinopathy from known patterns. The imaging exam is painless, quick and does not require dilation of the eyes, Liu says.

However, the step from the research bench to a real-world application would require effort outside the normal parameters of the laboratory. More partners in Mexico would be needed, Liu says.

“Real-world data have issues that may not occur in the lab,” Liu says. “Being able to cope with these constraints can be a real challenge.”

Working in real-world fields, however, is a must if you want to have a real impact in the real world.

Liu began working with the International Programs Office at Texas A&M, primarily Gabriel Carranza of the Office of Latin American Programs. Liu wanted a clearer idea of the issues in Mexico.

A successful effort to identify more partners in Mexico led to more funding that enabled clinical trials of the diagnostic screening mechanism, Liu says.

“My colleagues in Mexico have shown a sincere desire to embrace new solutions to deal with major problems,” Liu says.

In 2005, a diabetes imaging center opened in Mexico City in office space donated by Texas A&M graduate Pablo Marvin. The technology also is under consideration for trials in El Salvador.

“It takes time for this kind of new technology to penetrate,” Liu says.

Liu sees this sort of effort as a showcase for Texas A&M research, a chance for the university to reinforce its image in America and in other countries with technology leadership.

Keith Dannermiller/CORBIS

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The

BestofBoth Worlds

In this digital age of the 21st century, intellectual efforts are coming together in ways

that could have not been imagined 20 years ago. Huge chunks of information can now be shared over enormous distances almost instantly, thanks to high-speed Internet connections. This capability is changing the way people interact in scholarly endeavors.

With funding from the Texas A&M-CONACyT: Collaborative Research Grant Program, two prominent scientists caught this technological wave, making amazing breakthroughs in equine research. Dr. Katrin Hinrichs, associate professor in the College of Veterinary Medicine at Texas A&M University, and Dr. Salvador Romo, FES Cuautitlán, Universidad Nacional Autónoma de México, used a 2003 Texas A&M-CONACyT grant to attain new milestones in in vitro fertilization (IVF) in the horse.

Progress in equine IVF has been slow compared with that of other species, as the horse has proved to be a difficult subject. But Romo’s expertise in IVF of cows, combined with Hinrichs’ background in horse reproduction, made them the perfect team for this study. Each scientist offered a unique approach to the

large-animal reproductive cycle, and together they made significant progress. Specific laboratory procedures and suggestions could be shared freely thanks to electronic collaboration, and the results were astounding.

Hinrichs highlighted one such incident in this study. Research teams in Germany had achieved a 29 percent success rate when experimenting with the type of extender (the solution in which the equine sperm are frozen) used for the procedure. A skim-milk-based extender treated with heparin to enhance sperm performance proved to be the key. Her graduate student, Lance Roasa, duplicated these results in Hinrichs’ lab at Texas A&M University. As a result, the team succeeded in completing the first and second steps of in vitro maturation and IVF in equine oocytes.

This breakthrough has far-reaching implications for veterinary medicine. Prior to the Hinrichs–Romo research team’s effort, the only way to produce a fertilized egg in a laboratory was through intracytoplasmic sperm injection. This process requires expensive equipment and trained personnel that most veterinary practices can neither afford nor justify. With

the procedures developed by the Hinrichs–Romo team, however, fertilization can now be accomplished by using sperm treated with specific compounds and frozen, and then thawed and combined with eggs in a petri dish. Using the team’s refined IVF technique, combined with embryo transfer, could give veterinarians the tools to help produce offspring and extend the breeding capacity of many valuable mares that are not candidates for reproduction in the current environment.

The two scientists have slightly different visions of where they anticipate this field of research will be in 10 years.

Romo says, “I expect that in 10 years we will have a number of IVF foals produced, as well as cloned and transgenic horses derived from IVF embryos. I also expect that this technology will be used by then to create a genetic bank in which frozen embryos from many different equine breeds and lines are preserved.”

Hinrichs comments, “I am actually interested in the development of the oocyte within the embryo. I’ve always been fascinated with the final goal of finding

a way to make gametes from somatic cells. There are theoretically possible ways to take a skin sample and go through a series of procedures and end up on the other side with an egg.”

Both scientists agree that much more research of this kind is needed and that programs like the Texas A&M-CONACyT collaboration are instrumental in making it possible. Romo says, “By combining the distinctive strengths of two or more researchers in different countries, there is a synergistic effect. I am not surprised that great results are obtained by all parties involved: governments, universities, researchers, students and end users.”

The sharing of best practices across international boundaries uses new tools that are already beginning to revolutionize and illuminate the face of research in the 21st century. With the enthusiasm and dedication of teams like Hinrichs’ and Romo’s, important multinational research goals like theirs are rapidly becoming a reality.

by Vicki Sexton Holder

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Altered States

Among the health conscious, one of the most talked

about natural foods is the pecan. One nut contains a plethora of antioxidants, fiber and beneficial fatty acids, as well as nutrients such as folic acid, calcium, zinc, and vitamins A, B and E

Few know as much about pecans as Dr. Leonardo Lombardini — and few are more wary of the potential dangers involved in their transport.

Lombardini is a pecan physiologist and assistant professor of horticultural sciences at Texas A&M University. With funding from a Texas A&M-CONACyT grant, he and Emilio Villarreal, a Texas A&M graduate student in food science and technology, joined forces with Dr. Uriel Figueroa Víramontes, a soil fertility and plant nutrition expert at Mexico’s National Institute of Forestry, Agricultural and Animal Research (INIFAP).

Pecan crops in Texas and Mexico repeatedly cross back and forth across the border, presenting a tremendous risk for exchanging insects and other unwanted organisms. The researchers sought to determine whether irradiation should be viewed as a viable method of processing these pecans.

“Our goal was not to see whether or not irradiation is effective in killing microbes. That has been done before and we know it works,” Lombardini explains. “Rather, the goal of our project was to see if such a treatment somehow alters nutritional properties.”

Figueroa says that since electronic pasteurization is a new field in Mexico, the question of whether this process can be used to ensure food safety without compromising nutritional content is particularly relevant.

Soon, new regulations regarding food safety will affect pecan exportation from Mexico to the United States, Figueroa explains. “Electronic pasteurization is an alternative method to meet these regulations.”

Texas A&M-CONACyT funding enabled Lombardini and Villarreal to use the electron beam in the National Center for Electron Beam Food Research, housed on the Texas A&M campus. This process destroys infectious organisms during food processing. Through electron beam use and accelerated storage, the researchers determined that the only alteration in the pecans’ nutritional makeup was a slight decrease in vitamin E content.

In 2001 and 2004, the almond industry experienced its first-ever outbreaks of salmonella. The disease can often be linked to using manure as fertilizer late in the

Researchers study irradiation effects on nutritional properties of pecans

by Kara Bounds Socol

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by Kara Bounds Socol

study the organisms of the Yucatan’s Ox Bel Ha — the world’s largest underwater cave system.

The Ox Bel Ha cave system is a network of underground rivers stretching more than 88 miles. The system is interconnected with more than 60

ecosystems during the different stages of their life cycles,” he says. “If the flows of water, sediments, nutrients and organisms among these systems are interrupted, then adverse effects become immediately evident.”

Among these adverse effects, he says, is the complete

When Dr. Tom Iliffe was a research

scientist in Bermuda, he would wander into caves during his off time and examine their tidal pools. He wondered if any animals existed in those pools but soon learned that others had already studied the waters and concluded that they were lifeless.

But Iliffe was determined to check out the pools for himself. He donned his diving gear and jumped in — and his life was forever changed.

“On the surface of the pool was brackish water, but when you got about 20 feet down, you got into marine water where most of the cave-adapted animals live,” Iliffe recalls. “Diving was the key ingredient.”

Iliffe discovered a whole new world of sea creatures in that tidal cave pool, and a simple curiosity blossomed into a career. He has since circled the globe several times, exploring the biology of underwater caves and making the kinds of discoveries that have landed him on the pages of National Geographic. He shares this passion with his students at Texas A&M University at Galveston, where he is a professor of marine biology.

And now, thanks to funding from a Texas A&M-CONACyT grant, Iliffe has teamed up with Universidad Nacional Autónoma de México research scientist and crustacean expert Dr. Fernando Álvarez Noguera to

cave entrances — called “cenotes” — and flows into the Caribbean Sea though three outlets. Together with adjacent cave systems, more than 300 miles of submerged galleries have been surveyed and mapped. The goal of Álvarez and Iliffe is not to explore the actual caves but to determine the kinds of organisms that live there.

What they continue to discover is a host of previously unknown marine animals.

“We have been finding completely new major zoological groups at the family level that show that complete animal lineages have been evolving in these cave systems for long periods of time,” says Álvarez. “They have developed unique morphological structures and strategies to survive in this extreme environment.”

But discovering these new species is only a beginning: Álvarez and Iliffe want to ensure that they are protected. As experienced biologists, the researchers are well aware of the impact that large-scale development can have on fragile ecosystems. They are especially concerned about the booming Riviera Maya resort development in Tulum along Mexico’s Caribbean coastline.

Álvarez explains that the area’s marine ecosystems are interconnected. Damage to one, then, has a detrimental effect on the others.

“Many species make use of resources that flow between these systems and can live in different

Researchers discover new organisms in world’s largest underwater cave system

Cave MenPhotographer’s Choice RF/Peter Pinnock/Getty Images

by Kara Bounds Socol

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disappearance of many of these cave organisms.Iliffe and Álvarez are using their Texas A&M-

CONACyT grant to gather baseline information and data about the organisms in the Ox Bel Ha system. They will then use the information to apply for future grants, Iliffe says.

The funding also has allowed the researchers’ respective graduate students to work together — a benefit Iliffe says is one of the grant’s biggest advantages. A Texas A&M-CONACyT grant funded the research of one of his doctoral students, while another graduate student is interested in developing a similar project in Mexico.

Although Iliffe and Álvarez have collaborated on research projects for years, they have rarely done so face to face. Álvarez says that personal interaction is yet another benefit of the grant.

“With the Texas A&M-CONACyT grant, we had the chance to be in the field together for several weeks, explore the biodiversity of several systems for the first

season when nuts are falling from the trees and bacteria are still alive in the manure, Lombardini says.

“You just need one grower who doesn’t know how to use manure properly and you’ve got a serious problem,” he says.

Although the almond industry survived the ensuing recalls and reputation damage with minor bruises, Lombardini fears that a similar outbreak in the much smaller pecan industry would prove devastating. But since requiring producers to irradiate their pecans could add between 5 and 25 cents per pound to their cost (depending on the type of technology used), he doesn’t

know how willing they would be to voluntarily undertake this process.

“If the industry decides to adopt this technology when the pecans are sanitized, we could deliver a safe, unaltered product,” he says. “We don’t want to wait until an outbreak occurs.”

Altered States continued from Page13time, discuss results and have our students interact,” he says.

Ultimately, Álvarez and Iliffe hope their identification of the cave system’s organisms will help spur the kind of action needed to protect what they describe as part of the world’s most important biological and hydrological systems.

“To improve our understanding and better protect them,” Iliffe says, “we have to know what’s there.”

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The challenge to bolster the fisheries in reservoirs in rural Mexico ranges from big birds snagged in fishing nets to

trash rafts to fish growing smaller.To address this challenge, Dr. Frances Gelwick,

a fisheries ecologist in Texas A&M University’s Department of Wildlife and Fisheries Sciences has teamed with researcher Leticia Mar-Tovar of the Instituto de Investigaciónes Forestales, Agricoloas y Pecuarias (INIFAP) through a Texas A&M-CONACyT grant.

Gelwick and Mar-Tovar’s initial undertaking has grown to include funding from several Mexican agencies in addition to projects for graduate students from both countries.

The area of Mexico Gelwick and Mar-Tovar are concentrating on is Durango state in north-central Mexico, specifically the town of Lazaro Cardenas on the largest reservoir in the state. One goal is a management plan that balances what the reservoir can produce for fishing as well the potential for tourism and sport fishing.

“We are jointly developing a model for reservoir fisheries management that can be tailored for use elsewhere,” Gelwick said. “We might have some technology and methodologies they don’t have, but we also learn so much from them about their own values, attitudes, goals; and priorities for sustainable use of natural resources. These are some of the globally important human dimensions of natural resources management that students are taught to consider as they study for their degree in our department.”

Mar-Tovar first contacted Gelwick in 1999 while looking for information about reservoir fisheries. “I found her e-mail address on the Texas A&M Web site, and she was kind enough to answer my questions,” said Mar-Tovar.

INIFAP has a mission similar to Texas A&M’s extension faculty to promote research, technology transfer and public outreach.

Those questions grew into their initial meeting through the Texas A&M Faculty Abroad Seminar and an International Research and Education Travel Grant

through the Association of Former Students. These led to their initial Texas A&M-CONACyT collaboration

and additional funding by other agencies. That included trips by six Mexican researchers to

workshops and to visit with Texas A&M faculty and their colleagues at Texas Parks and

Wildlife research facilities across Texas.Over the past six years, Gelwick has made

several trips to Mexico. She was joined by Dr. Tazim Jamal of the Texas A&M Department of Recreation Parks and Tourism Sciences, and student researcher Natalie Ibarra from Texas A&M International University, Laredo. Ibarra was sponsored by a National Science Foundation

Program for Undergraduate Mentoring in Environmental Biology in collaboration with

co-mentors Dr. Sushma Krishnamurthy and Dr. Thomas Vaughan at Ibarra’s home university.

Their efforts created the potential for Mar-Tovar to study for her doctorate with Gelwick at Texas

A&M, based on their El Palmito project. Other research participants are faculty and students in the veterinary school at the University of Juarez in

Durango, and they are working to develop studies in fisheries management.

El Palmito on the Rio Nazas is the fourth largest reservoir in Latin America and was originally intended to collect water for irrigating crops and flood control. However, its use has grown to support a community of about 100 commercial fishers and – hopefully – other future aquatic endeavors perhaps including tourism, according to Mar-Tovar.

“We are doing many things to help people in rural areas to achieve a sustainable management of our aquatic resources,” Mar-Tovar said.

Gelwick notes because the reservoir was not originally created for fishing and other uses beyond irrigation and flood control, the fishery has developed problems, which the collaborative researchers aim to resolve.

One example is the fish-eating birds, cormorants, a migratory species protected by the U.S. Fish and Wildlife Service. Dead cottonwood trees along the original banks of the Rio Nazas provide roosting and nesting sites that increase habitat and population density of these birds, Gelwick said.

“The birds not only eat lots of fish, but also become entangled in, and damage, fishing nets,” Gelwick said.

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Another problem is the use of the river for waste disposal by people living farther upstream. “The result is a trash raft that can stretch hundreds of yards through the otherwise-scenic canyon lands carved by the once-flowing upstream reach of river that now functions more like a lake,” Gelwick said.

Problems extend to the fish populations, Gelwick said. The Rio Nazas is an endorheic, or ”sinking”, river basin (meaning it does not flow into the ocean), and contains at least one unique fish species (presently under study by Dr. Hank Bart at Tulane University).

As in reservoirs world-wide, other (often non-native) species more adapted to non-flowing water are routinely stocked to maintain a reservoir fishery, Gelwick said.

“Blue tilapia, European carp, and channel catfish (traditional favorites for aquaculture), as well as bluegill, largemouth bass and white crappie (all in the sunfish family), are popular fishes in Mexico,” she said.

Sunfishes are adapted for surviving in dense populations under stressful conditions. These fish reproduce multiple times a season, becoming crowded in the reservoirs and grow slowly unless their high reproduction is countered by predation. However, under additional pressure from human fishers, fish may not live

Texas A&M University - CONACyT: Collaborative Research Grant Program

Texas A&M University and the Consejo Nacional de Ciencia y Tecnologia (CONACyT) signed a five-year agreement of cooperation in higher education and research in April 2001. Priority programs were established and it was agreed that the parties would undertake joint programs in areas of mutual interest including:

1. Graduate Student Education and Post-graduate Certification 2. Exchange of Faculty and Researchers 3. Non-degree Student Training 4. Collaborative Research Programs 5. Promotion of Joint Programs

Under this agreement Texas A&M and CONACyT have each dedicated US$200,000 per year for five years for the Collaborative Research Grant Program to fund inter-institutional research proposals between Texas A&M and Mexican institutions.

The purpose of the competitive, peer reviewed Collaborative Research Grant Program is to advance inter-institutional cooperation in science, technology, and scholarly activities through the complementary efforts of scientists and scholars from Texas A&M and Mexican institutions. A principal investigator (PI) is required from both Texas A&M University and a CONACyT-registered institution. Texas A&M and CONACyT leaders have agreed on several research priority areas: 1. Biotechnology and Bioinformatics 2. Health 3. Telecommunications/Information Technologies 4. Environment; 5. Advanced Materials and Manufacturing 6. Energy 7. Urban Development and Sustainability

The research must be linked to the private sector and have direct application to solving an in-dustrial or governmental problem. One major objective of the program is to support the devel-opment and submission of proposals for external funding from competitive granting agencies, both domestic and international, and industry.

The following pages list awards that have been made for the last five years.

long enough to grow larger.“The size per individual fish is important to the

commercial fishers and those who buy fish for local markets, restaurants and their own families,” Gelwick said. “A management plan incorporates the various problems all together in order to find alternative optimal solutions.”

Bryan L. Lambert/Shutterstock Images

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Texas A&M University Principal Investigator

Texas A&MDepartment

Mexican Principal Investigator

CONACyTRegistered Institution

GRANT TITLE

Wendy Jepson; Christian Brannstrom

Geography Gustavo Garza; Casey Walsh

UNAM An Integrated Assessment of Cross-Border Land and Water-Use Changes in the Lower Rio Grande/Bravo Valley Since 1990

Alexander Sprintson Electrical Engineering Sergio Rajsbaum UNAM Combating Failures and Malicious Attacks in Communication Networks

Wayne Hung Engineering Technology and Industrial Distribution

Luis Godinez Mora-Tovar CIDETEQ Electrochemical Technology Development for Micro/nano Manufacturing

Christine Budke Veterinary Integrative Biosciences

Ana Flisser National University of Mexico Estimating the non-monetary and monetary burden of Taenia solium cysticercosis in Mexico

Lloyd Rooney Soil and Crop Sciences Sergio Serna-Saldivar ITESM Evaluation of Phenolics, Antioxidant and Anticancer Properties of Sorghums

Yassin Hassan Nuclear Engineering Claudia del Carmen Gutier-rez-Torres

IPN High Efficiency Air Cleaning Cyclone Separators

Sheng-Jen Hsieh Engineering Technology and Industrial Distribution

Ismael Lopez-Juarez CINVESTAV Hybrid Active Imaging Techniques for Potato Inspection

Marcos Sanchez-Plata Poultry Science Ernesto Avila Gonzalez UNAM Improving the Fatty Acid Composition and Shelf-life Stability in Eggs and Poultry Meat from Poultry Fed with Dietary Levels of Omega-3 Fatty Acids and Conjugated Linoleic Acid

Alejandro Castillo Animal Science Alejandro Lopez-Malo Universidad de las Americas, Puebla

Microbiological Safety of Fresh and Fresh-Cut Produce

Christopher Marshall Marine Biology Axayacatl Rocha-Olivares CICESE New Solutions to Solving Sea Turtle Bycatch from Fisheries Industry Gear in both U.S. and Mexican Waters

Marla Binzel Horticultural Science Omar Pantoja UNAM-Instituto de Biotecnologia

Phytoremediation: merging biotechnology and native species

Luis Cifuentes Oceanography Felipe de Jesus Carrillo Romo

CICATA Altamira-IPN Polynuclear Aromatic Hydrocarbons and their accumulation by the American oyster Crassostrea virginica in the Pueblo Viejo lagoon, Veracruz and Laguna Madre, Tamaulipas

Gerald Wagner Veterinary Pathobiology Alfredo Sahagun Ruiz UNAM Preventing colibacillosis Diarrhea in Bovine Calves with Anti-F5 Recombinant Antibodies Produced in Rice Plants

Nancy DyerGregory Cuellar

Hispanic StudiesLibrary

Blanca Guadalupe Lopez Morales

Tecnológico de Monterrey Retrieval and Interpretation of Shared Cultural Memory from the New Spain Collections of the Cushing Library (Texas A&M) and the Biblioteca Cervantina (Tec de Monterrey)

Luis Cisneros Horticultural Science Zevallos Carmen Hernan-dez-Brenes

ITESM Strengthening the Mexican and U.S.-Avocado Industry by Developing Value-added Processed Avocados and By-prod-ucts as Functional Foods for Protection against Cardiovascular Disease

Shankar Bhattacharyya Electrical Engineering Maria Cristina Verde Ro-darte

National University in Mexico Synthesis of Three Term Controllers Free of Analytical Model Acronymn: SCFAM

2006 Texas A&M University - CONACyT Awards

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200� Texas A&M University - CONACyT Awards

Texas A&M University Principal Investigator

Texas A&MDepartment

Mexican Principal Investigator

CONACyTRegistered Institution

GRANT TITLE

Leslie G. Adams Veterinary Pathobiology Jose Gutierrez-Pabello FMVZ-UNAM Association of Natural Disease Resistance in Cattle and Macrophage Inflammatory Gene Expression Profiles

Christine Ehlig-Economides Petroleum Engineering Alberto Mendoza Instituto Tecnológico y de Estudios Superiores de Monterrey

Comparing Combustion and Syngas Processes using Petroleum Coke (Pet-Coke) and Coal for Industrial Heat and Power Generation

Jorge Alvarado Engineering Technology and Industrial Distribution

Jose Mireles, Jr. UACJ Development, Calibration and Implementation of a Micro-Scale Flow Meter

S. Vinson Entomology Hector Gonzalez-Hernan-dez

CP Developing Environmentally Friendly Management Technologies for Emerging Insect Pests of Tequila Agave

Thomas Ficht Veterinary Pathobiology Efren Diaz-Aparicio INIFAP Development of Brucella canis virB Mutants and its Study in a Cellular Model

Ricardo Gutierrez-Osuna Computer Science Isaac Rudomin ITESM-CEM Facial Caricaturing as a Training Tool for Security

Manuel Soriaga Chemistry Nikola Batina Universidad Autonoma Metropoli-tana-Iztapalapa (UAM)

Green Electronalytical Chemistry: Remote Trace-Level Selenium Sensor

Julio Bernal Entomology Enrique Aranda-Herrera Monterrey Institute of Technology (ITESM)

Integrated Pest Management for Pecans in the Laguna Region of Coahuila

Prasad Enjeti Electrical and Computer Engineering

Jaime Arau CENIDET Investigation of Fuel Cells for Distributed Energy

Chii-Der Suh Mechanical Engineering Martin Baltazar Lopez CENIDET Mango Slices Dryer Using Continuously Fed Air Heated by Solar Energy

Sergiy Butenko Industrial and Systems Engineering

Yuriy Shkvarko Cinvestav del IPN Optimization Algorithms for Network Design and Data Processing in Remote Sensing

Suresh Pillai Poultry Science Ilangovan Kuppusamy Instituto Tecnológico y de Estudios Superiores de Monterrey

Quantifying Health Risks in Mexico Associated with Contaminated Fruits and Vegetables via Pathogens in Irrigation Water

Stephen Searcy Biological and Agricultural Engineering

Juvenal Guiterrez-Castillo Tecnológico de Monterrey Use of Precision Agriculture Technologies to Reduce the Overuse and Degradation of Water in Pecan Production

Allison Rice-Ficht Molecular and Cellular Medicine

Gilberto Chavez Gris Universidad Nacional Autonoma de Mexico

Validation and Development of Diagnostic Assays for Mycobacterium paratuberculosis infections

Duane Kraemer Veterinary Physiology and Pharmacology

Salvador Romo UNAM Vitrification of in vivo and in vitro-Derived Brahman Cattle Embryos

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2004 Texas A&M University - CONACyT Awards

Texas A&M University Principal Investigator

Texas A&MDepartment

Mexican Principal Investigator

CONACyTRegistered Institution

GRANT TITLE

L. Garry Adams Veterinary Pathobiology Alberto Morales-Loredo INIFAP-ITESM A Recombinant Vaccine for Simultaneous Protection of Goats Against Brucellosis and Orf

Ranjita Misra Health and Kinesiology Roxana Valdes-Ramos UAEM Determinants, Outcomes and Burden of Diabetes and Cardiovascular Disease among Mexicans and Mexican Ameri-cans: Need for a Public and Private Sector Partnership

Wayne P. Hung Engineering Technology and Industrial Distribution

Francisco J. Ruiz-Sanchez CINVESTAV Development of Automation Technique for Microrobotic Applications

Leonardo Lombardini Horticulture Science Uriel Figueroa Viramontes INIFAP Effect of Electronic Pasteurization on Nutritional Properties and Shelf-life of Pecan Kernels

Luis Cisneros-Zevallos Horticulture Science Carmen Hernandez-Brenes ITESM Improving the Security of Food Products Through the Use of Antimicrobial Substances in Combination with Novel Processing Technologies

Ricardo Gutierrez-Osuna Computer Science Ismael Lopez-Juarez CIATEQ Improving the Security of Food Products Through the Use of Antimicrobial Substances in Combination with Novel Processing Technologies

S. Vinson Entomology Eusebio Juaristi Cinvestav IPN Insecticidal Agents Based on Neuropeptide Analogs Containing beta-Amino Acids

Robin Autenrieth Civil Engineering Diego Corcho-Sanchez Universidad Veracruzana Integrated Strategies for the Protection of Water Resource Quality in a Coffee Processing Region of Veracurz, Mexico

Marvin K. Harris Entomology Agustin C. Fu INIFAP National Security Enhancement Through Pecan IPM Research and Program Development in Mexico and Texas

David Goodman Chemistry Pankaj Sharma UNAM New Organometallic Precursors for the Deposition of Pnictogen-chalcogenide Thin Films

Julio S. Bernal Entomology Juan F. Barrera Gaytan ECOSUR Promoting Organic Coffee Production in Chiapas through Pest Management, Agronomic, and Economic Research

Hongbin Zhan Geology and Geophysics Rogelio Vazquez-Gonzalez CICESE Sea Water Upcoming under Pumping Horizontal Wells in Coastal Aquifers

Robert Wharton Entomology Martin Aluja Instituto de Ecologia The Natural Enemies of Rhagoletis spp. (Diptera: Tephritidae) in Mexico, with Emphasis on the Apple Maggot, Rhago-letis pomonella

Suresh Pillai Poultry Science Ilangovan Kuppusamy ITESM Ultrasonic Technology for Waste Water Disinfection

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200� Texas A&M University - CONACyT Awards

Texas A&M University Principal Investigator

Texas A&MDepartment

Mexican Principal Investigator

CONACyTRegistered Institution

GRANT TITLE

Thomas J. DeWitt Wildlife and Fisheries Sciences

Luis Zambrano UNAM Biodiversity Assessment and Community Ecology of Yucatan Wetland Fish Assemblages

John R. Gold Wildlife and Fisheries Sciences

Axayacatl Rocha-Olivares CICESE Development of Biotechnological Tools to Aid in Stock Delineation in California Pacific Sardine

Alejandro Castillo Animal Science Rosalba Gutierrez Rojo CIATEDJAL Development of a Polymerase Chain Reaction (PCR) Method for Detecting Enterobacter Sakazakii in Infant Milk Formulas

Paul N. Roschke Civil Engineering Francisco Yeomans Reyna ITESM Dynamic Failure of a Thermally Efficient Structural Dome

Thomas M. Iliffe Marine Biology Fernando Alvarez UNAM Ecology, Biodiversity and Hydrology of Anchialine Caves: the Ox Bel Ha System, Quintana Roo, Mexico

James B. Woolley Entomology Alejandro Gonzalez Her-nandez

Universidad Autonoma de Nuevo Leon

Encyrtid Parasitoids of Mealybugs in Mexico

Yassin A. Hassan Nuclear Engineering Javier Ortiz-Villafuerte ININ Experimental Study of Drag Reduction within Boundary Layer using Particle Image Velocimetry and Hot Film Measurement Techniques

Katrin Hinrichs Veterinary Physiology and Pharmacology

Salvador Romo UNAM In Vitro Fertilization in the Horse

Prasad N. Enjeti Electrical and Computer Engineering

Jose L. Duran-Gomez Instituto Tecnologico de Chihuahua

New Approaches to Provide Electric Energy by Alternative Renewable Resources (ARR)

L. Garry Adams Veterinary Pathobiology Ricardo Gomez Florez UANL Production and Evaluation of Brucella Melitensis Native Hapten Conjugated with Gluorescein Isotiocianate for the Diagnosis of Brucellosis by the Fluorescent Polarized Assay

Cesar O. Malave Industrial and Systems Engineering

Enrique Palou Universidad de las Americas Puebla Center for Engineering Education

Jyhwen Wang Engineering Technology and Industrial Distributation

Carlos Acosta Universidad de las Americas Puebla Design and Analysis of Dual Tube Hydroforming Process

Marla L. Binzel Horticultural Science Omar Pantoja UNAM Regulation of H+ Pumps by Vacuolar H+ Dependent Transporters?

William H. Neill Wildlife and Fisheries Sciences

Alejandro Buentello-Garcia CIBNOR Strategic Research to Increase Fisheries Productivity and Strengthen the Tuna Aquaculture Industry in Northwest Mexico: The Yellowfin Tuna Plan

Frances I. Gelwick Wildlife and Fisheries Sciences

Leticia Mar Tovar UAS Strategies for Sustainable Management of Fisheries Resources in Durango, Mexico

Nilesh S. Chatterjee Health and Kinesiology Rafael Chorne Navia UACOAH Understanding Individual, Social, Cultural, Environmental Determinants of Diabetes in Mexicans and Mexican Ameri-cans: A Pilot Study

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2002 Texas A&M University - CONACyT Awards

Texas A&M University Principal Investigator

Texas A&MDepartment

Mexican Principal Investigator

CONACyTRegistered Institution

GRANT TITLE

Kirby Donnelly Environmental and Occupational Health

Karim Acuna-Askar Universidad Autonoma de Nuevo Leon

Biomarkers of Chemical Exposure and Sensitivity in Populations on the Texas-Mexico Border

Maria Barrufet Petroleum Engineering Gustavo Iglesias Silva–Instituto Tecnológico de Calaya

Design and Optimization of Oil Field Brine Conversion Processes to Water of Irrigation Quality

Reza Langari Mechanical Engineering Edgar Sanchez Centro de Investigación y de Estu-dios Avanzandos del IPN

Development of Intelligent Rollover Warning and Control Systems for Tractor- Semitrailers

L. Garry Adams Veterinary Pathobiology Jose Angel Gutierrez Pa-bello

Universidad Nacional Autonoma de Mexico

Influence of the Host Genetic Background; the Bacterial Virulence and Mycobacterial Peptides in Bovine Macrophage

Claire Williams Forest Science M. Humberto Reyes Valdes Universidad Autonoma Agraria “Antonio Narro”

Information Theory to Forest Genomics

Ayal Anis Texas A&M University at Galveston

Martin Merino Universidad Nacional Autonoma de Mexico

Investigation of the Physical and Biogeochemical Processes in Valle de Bravo Freshwater Reservoir

Mahlon Kennicutt, III Oceanography Elva Escobar Briones and Pedro Morales Puetno

Universidad Nacional Autonoma de Mexico, Instituto de Ciencias del Mar y Limnologia, Ciudad Univer-sitaria and Universidad Nacional Autonoma de Mexico, Instituto de Geologia, Laboratorio de Isotopia Estable

Methane in Marine Karst Environments: A Joint U.S./Mexico Interdisciplinary Program

Chuck Kenerley Plant Pathology and Microbiology

Alfredo Herrera-Estrella Centro de Investigación y de Estu-dios Avanzandos del IPN

Molecular Basis of the Mycoparasitic Response in the Biocontrol Fungus Trichoderma

Ian MacDonald Oceanography Elva Escobar Briones Universidad Nacional Autonoma de Mexico

Natural Hydrocarbon Seeps of the Gulf of Mexico

Steve Liu Computer Science Jorge Enrique Preciado Velasco and Roberto Conte Galvan

Centro de Investigación Cientifica y de Educacion Superior de Ensenada

On the Development of a Virtual Software System Laboratory Architecture and its Prototype

Luis Cisneros-Zevallos Horticulture Science Carmen Hernandez Tecnologico y de Estudios Superi-ores de Monterrey

Process Development and Health Benefits of Value-added Functional Extracts from Native American Crops for their use in the U.S. Food and Pharmaceutical Industry

John Moroney Economics Flory Anette Dieck Assad Instituto Tecnologica y de Estudios Superiores de Monterrey

Sustainable Growth: Mexico and the United States

Ozden Ochoa Mechanical Engineering Sergey Kanaun Instituto Tecnologica y de Estudios Superiores de Monterrey

Theoretical and Experimental Investigation of Carbon Foam Composites

Merwyn Kothmann Rangeland Ecology and Management

Heriberto Diaz Solis Universidad Automoma Agraria “Antonio Narro”

User-Oriented Models for Assessing Ecological and Economic Drought Risks on Semi-Arid Rangelands

Sheng-Jen Hsieh Engineering Technology and Industrial Distribution

Manual Macias Instituto Tecnologico y de Estudios Superiores de Monterrey

Virtual Laboratory for Advanced Manufacturing Automation and Control

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Texas A&M University

Texas A&M University - CONACyT: Collaborative Research Grant ProgramOffice of the Vice President for ResearchTexas A&M University312 Williams Administration BuildingCollege Station, Texas 77843-1112