Systemic Approach to Advanced Colon Cancer Mohamed Abdulla (M.D.) Ass. Prof. Clinical Oncology Kasr...
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Transcript of Systemic Approach to Advanced Colon Cancer Mohamed Abdulla (M.D.) Ass. Prof. Clinical Oncology Kasr...
Systemic Approach to Advanced Colon
CancerMohamed Abdulla (M.D.)
Ass. Prof. Clinical OncologyKasr El-Aini School of Medicine
Cairo UniversityApril, 2005
Heterogeneous Groups of Patients Several Agents
Different SchedulesPharmacogenomic
Variations
Which Regimen to Be Used as a First Line ttt in Advanced or Metastatic Colon
Cancer???
DON’T FORGET
5-Fu is no longer the only cytotoxic agent with clinical activity.
Capecitabine is an effective alternative to infusional 5-Fu.
Oxaliplatin & Irinotecan have nearly doubled the median survival.
Oxaliplatin improves PFS. Initial validation of the promising
systemic target therapies.
Highlights of the American Society of Clinical Oncology 2005 Gastrointestinal Cancers Symposium, Feb. 2005.
Seminars in Oncology; Volume 32, Number 1, 2004-2005.
www.medscape.com www.mdconsult.com
ANNOUNCEMENT