Neuroimaging of typical and atypical brain development

(and intervention response !)

Signe Bray, PhD

NDN: NeuroGame 2014

Research areas

1. Intervention– Medication / exercise

2. Reinforcement learning– Abnormal in ND Disorders?

3. Visual-spatial attention– Typical and atypical development– Effects of intervention?

4. Typical development of brain networks

Potential: pre / post imaging

Assess changes in:

– Blood flow / perfusion

– Properties of white matter connections

– Functional interactions between brain regions

– Task-dependent activation

Research areas

1. Intervention– Medication / exercise

2. Reinforcement learning– Abnormal in ND Disorders?

3. Visual-spatial attention– Typical and atypical development– Effects of intervention?

4. Typical development of brain networks

Reinforcement learnin

Research areas

1. Intervention– Medication / exercise

2. Reinforcement learning– Abnormal in ND Disorders?

3. Visual-spatial attention– Typical and atypical development– Effects of intervention?

4. Typical development of brain networks

Visual-spatial attention / working memory

• Development in early childhood

• Atypical development in:

– Pre-term birth

– Turner syndrome

• Possibilities for intervention

Research areas

1. Intervention– Medication / exercise

2. Reinforcement learning– Abnormal in ND Disorders?

3. Visual-spatial attention– Typical and atypical development– Effects of intervention?

4. Typical development of brain networks

Development of brain networks

• Intervention timing?

Discussion

Computerized

vs.

interactive / social / physical

?

THANK YOU

Harriet JohnstonManuele SchuetzeSarah VinetteSarah RahmanIvy ChoKeelin RivardMark KrongoldBrian CechmanekCassandra Cooper

Deborah DeweyAdam McCrimmonAndrea ProtznerElizabeth TricomiCatherine LebelFrank MacMaster