ROFESSOR OF MEDICINE EMORY UNIVERSITY SCHOOL OF … Collop 3-23-17.pdfappointment in the Emory...
Transcript of ROFESSOR OF MEDICINE EMORY UNIVERSITY SCHOOL OF … Collop 3-23-17.pdfappointment in the Emory...
FUTURE OF SLEEP MEDICINE NANCY A. COLLOP, MD PROFESSOR OF MEDICINE EMORY UNIVERSITY SCHOOL OF MEDICINE ATLANTA, GA
Nancy A. Collop, MD, is the director of the Emory Sleep Center in Atlanta, Ga and was the 2011-2012 president of the American Academy of Sleep Medicine (AASM). She holds a primary appointment in the Emory School of Medicine as professor of Medicine in the Division of Pulmonary, Allergy, Critical Care Medicine and Sleep Medicine, as well as a secondary appointment as professor of Neurology. She became an AASM member in 1990 and earned board certification in sleep medicine from the American Board of Sleep Medicine in 1997. She has held ABMS board certification in internal medicine, pulmonary medicine, critical care and sleep medicine. Collop has held academic positions at the Medical University of South Carolina, University of Mississippi, and Johns Hopkins University in Baltimore, MD, where she was the medical director of the Johns Hopkins Hospital Sleep Disorders Center. She served on the AASM board of directors since 2006 and served as Secretary – Treasurer (2008-10) and President Elect (2010-11), President (2011-12) and Past President (2012-13). She has held numerous leadership positions in other professional societies and organizations. Collop has served on the American Board of Sleep Medicine (ABSM) board of directors since 1998, holding the position of ABSM president from 2002-2009. She was a member of the board of directors of the American Sleep Medicine Foundation, for which she previously served on the Executive Committee and as Secretary – Treasurer. Collop also was on the founding committee of the American Board of Medical Specialties Sleep Medicine Examination Committee representing the American Board of Internal Medicine (ABIM), and served for several years on the ABIM Pulmonary and Sleep Medicine Self Evaluation Process committees. She has served on the board of directors for the Chest Foundation. She was a Founding member of the Maryland Sleep Society and their first president; she served on the board of directors of GASP (Georgia Associated Sleep Professionals) from 2013-2015. Collop has been named one of the “Best Doctors in America” and a Distinguished Alumna for Natural Sciences by Edinboro University. She also has received several prestigious awards, including the Al Soffer Award for Editorial Excellence and the College Medalist from the American College of Chest Physicians, the Helmut S. Schmidt Award from the American Board of Sleep Medicine, the “Pulmonary Star” Award from the Emory Division of Pulmonary/Critical Care/Allergy/Sleep. She was awarded the “Distinguished Service Award” from the Maryland Sleep Society (2015) and at Sleep 2015 received the Nathanial Kleitman Distinguished Service Award from the AASM. She is currently the Editor-in-Chief of the Journal of Clinical Sleep Medicine and the Section Editor of Sleep Medicine for Up-To-Date. She was associate editor of the journal Chest for 22 years and
now is on their Editorial Board. A recognized expert in sleep-related breathing disorders, Collop has conducted research and co-authored numerous studies on topics such as diagnostic testing for sleep-disordered breathing, the treatment of obstructive sleep apnea (OSA), and the relationship between sleep apnea and comorbid medical conditions such as Down syndrome and chronic obstructive pulmonary disease. She has authored 74 manuscripts, 44 book chapters or monographs and numerous editorials, letters and case reports. Dr. Collop has chaired numerous important taskforces on the topic of home sleep testing and is considered an expert on this subject. She was the lead author of the landmark paper, “Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients,” which was published in the December 2007 was the task force chair and lead author of the AASM’s technology evaluation of OSA devices for out of center sleep testing, published in October 2011. OBJECTIVES: Participants should be better able to:
1. Understand the brief history of how sleep medicine has advanced over the last 3 decades;
2. Be knowledgeable about the role of home sleep apnea testing and current HSAT guidelines;
3. Appreciate the challenges to manage a growing number of patients with sleep disorders;
4. Be able to discuss future plans to deal with the challenges of too few providers and too many patients
THURSDAY, MARCH 23, 2017 11:15 AM
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DISCLOSURE
Dr. Collop has received research grants from Jazz Pharmaceuticals and Simmons Bedding and has received honorarium from UpToDate, but these do not create a conflict of interest related to the following presentation.
Nancy Collop, M.D.
Professor, Emory University
Atlanta, GA
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Objectives Review the history of the growth of sleep medicine as a field
Discuss current challenges to the field of sleep medicine
Consider the future of sleep medicine and how the field needs to position itself to continue to be successful
History Lesson “Study the past if you would define the future.” ― Confucius
“If you don't know history, then you don't know anything. You are a leaf that doesn't know it is part of a tree. ” ― Michael Crichton
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The Early Days Stanford Narcolepsy Clinic – 1964
Rechtschaffen and Kales edited sleep staging manual ‐1968 Ralph Berger, William Dement, Allan Jacobson, Laverne Johnson, Michel Jouvet, Lawrence Monroe, Ian Oswald, Howard Roffwarg, Bedrich Roth, Richard Walter
Stanford Sleep Center opened – 1970
Sleep Research and Treatment Center at Penn State University in Hershey (Anthony Kales) – 1971
BC of CA began reimbursing for sleep studies – 1975
Association of Sleep Disorders Centers forms ‐ 1975
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QUESTION #1When was the first sleep laboratory accredited by the American Sleep Disorders Association (now known as the American Academy of Sleep Medicine)?
A.1964B.1970C.1977D.1985E.1991
A. B. C. D. E.
2% 2%
46%42%
8%
QUESTION #1When was the first sleep laboratory accredited by the American Sleep Disorders Association (now known as the American Academy of Sleep Medicine)?
A. 1964B. 1970C. 1977D. 1985E. 1991
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First Sleep Center Accredited
April 27, 1977
Question #2Who was the first person to describe obstructive sleep apnea on a sleep study?
A.BurwellB.DickensC.KleitmanD.DementE.Gastaut
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A. B. C. D. E.
11% 14% 11%
41%
23%
Question #2Who was the first person to describe obstructive sleep apnea on a sleep study?
A. BurwellB. DickensC. KleitmanD. DementE. Gastaut
What Did We Know in 1980? Burwell (1956) described obesity hypoventilation syndrome
Dement, Kleitman (1957) described 5 stages of sleep including REM
Vogel (1960) noted REM sleep onset in narcolepsy
Gastaut (1966) described obstructive apneas on a sleep study
Gene for per discovered in Drosophila (1971)
Remmers (1978) found the upper airway collapse was associated with the genioglossus muscle
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Nasal CPAP Described ‐ 1981Lancet. 1981 Apr 18;1(8225):862‐5.
Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares.
Sullivan CE, Issa FG, Berthon‐Jones M, Eves L.
AbstractFive patients with severe obstructive sleep apnoea were treated with continuous positive airway pressure (CPAP) applied via a comfortable nose mask through the nares. Low levels of pressure (range 4.5‐10 cm H2O) completely prevented upper airway occlusion during sleep in each patient and allowed an entire night of uninterrupted sleep. Continuous positive airway pressure applied in this manner provides a pneumatic splint for the nasopharyngeal airway and is a safe, simple treatment for the obstructive sleep apnoea syndrome.
History of Organized Sleep Medicine “International Classification of Sleep Disorders Manual” published 1979
1st revision 1985
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History of Organized Sleep Medicine “International Classification of Sleep Disorders Manual” published 1979
1st revision 1985
2nd edition 2005
3rd edition 2013
Journal dedicated to sleep (Sleep) – 1978
National Center on Sleep Disorders Research (NCSDR) created within the NIH in 1993
Sleep Medicine recognized as a specialty by the AMA (1995)
AASM appointed seat in AMA house of delegates (1997)
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Education and Certification Education about sleep medicine varied between specialties
Certification examination as initial step to standardize education First exam on “clinical polysomnography” given 1978 ( 1st certificate given to DrWilliam Dement)
1980 – exam became 2 parts to cover all aspects of sleep medicine (initially part 2 as an oral exam)
1990 – became American Board of Sleep Medicine – 514 had passed exam to date; Helmet Schmidt was 1st president
Sleep Medicine Fellowship training committee formed in AASM in 1988 –set out to standardize training with ultimate goal to become recognized by ACGME
Summary of progress in 20th centuryNosology
Dedicated journal
National society
Annual meeting (SRS held first meeting in 1961)
Recognized specialty (AMA)
Certification examination
Training programs (31 AASM accredited fellowships)
NIH center
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The 21st Century ABSM continues to offer certification up until 2006
3445 diplomates
2000: AASM holds first meetings with ABIM and ABPN
2002: 53 AASM approved sleep fellowship programs; AASM submits application to ACGME
2003: ACGME approves certification for sleep fellowships; Application to ABMS submitted for certification examination in sleep medicine
2005: ABMS approves subspecialty examination; ACGME begins to accredit sleep fellowship programs
2007: 1st ABMS specialty examination in sleep medicine is administered
Snapshot of Today ~ 8000 board certified sleep specialists
75 sleep fellowship training programs representing 180 slots
2500 accredited sleep centers
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AASM Accredited Centers
Snapshot of Today ~ 8000 board certified sleep specialists
78 sleep fellowship training programs representing 180 slots
2500 accredited sleep centers
~10,000 members of the AASM
Annual meeting draws 5‐6000 attendees; > 125 sessions, 1500 abstracts
Associated societies: SRS, AADSM, AAST, SBSM
Certification examinations for technologists, dentists, behavioral sleep medicine specialists
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What have been the biggest changes? Diagnostic measurement of sleep – polysomnography
Billable procedure
CPAP and its commercialization
AASM center certification
AASM → ACGME sleep fellowships
ABSM → ABMS certification
Acceptance of home sleep apnea testing
Timeline of PM→ HST → HSAT
1994:
ASDA PP’s for the use of Portable Recording
Cardiovascular consequences for Sleep Apnea (SHHS) - Level II devices used > 6000 subjects
2004:
Trisociety Evidence review, Practice Parameters released;CMS re-evaluates PM2005: CMS agrees not ready
2007:
AASM PM Taskforce Guidelines publishedCMS releases 2 AHRQ Evidence Reviews and preliminary decision
2008: CMS decides PM is adequate to determine OSA diagnosis in order to provide CPAP
2010: CPT sleep codes are reviewed -preliminary decisions released
2011: CMS releases new reimburse-ment levels for PSG and makes PM codes no longer T codes
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Littner MR, Semin Respir Crit Care Med 2005;26:56-57
Timeline of PM→ HST → HSAT
1994:
ASDA PP’s for the use of Portable Recording
Cardiovascular consequences for Sleep Apnea (SHHS) - Level II devices used > 6000 subjects
2004:
Trisociety Evidence review, Practice Parameters released;CMS re-evaluates PM2005: CMS agrees not ready
2007:
AASM PM Taskforce Guidelines publishedCMS releases 2 AHRQ Evidence Reviews and preliminary decision
2008: CMS decides PM is adequate to determine OSA diagnosis in order to provide CPAP
2010: CPT sleep codes are reviewed -preliminary decisions released
2011: CMS releases new reimburse-ment levels for PSG and makes PM codes no longer T codes
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CAG # 00405N (3/9/09)Sleep Testing for Obstructive Sleep Apnea
CMS finds that the evidence is sufficient to determine that the results of the sleep tests identified below can be used by a beneficiary’s treating physician to diagnose OSA, that the use of such sleep testing technologies demonstrates improved health outcomes in Medicare beneficiaries who have OSA and receive the appropriate treatment, and that these tests are thus reasonable and necessary under section 1862(a)(1)(A) of the Social Security Act.
Therefore: Type I Polysomnography (PSG) is covered when used to aid the diagnosis of
obstructive sleep apnea (OSA) in beneficiaries who have clinical signs and symptoms indicative of OSA if performed attended in a sleep lab facility.
CAG # 00405N (3/9/09)Sleep Testing for Obstructive Sleep ApneaTherefore:
A Type II or a Type III sleep testing device is covered when used to aid the diagnosis of
obstructive sleep apnea (OSA) in beneficiaries who have clinical signs and symptoms indicative
of OSA if performed unattended in or out of a sleep lab facility or attended in a sleep lab facility.
A Type IV sleep testing devicemeasuring three or more channels, one of which is airflow, is
covered when used to aid the diagnosis of OSA in beneficiaries who have signs and symptoms
indicative of OSA if performed unattended in or out of a sleep lab facility or attended in a sleep
lab facility.
A sleep testing device measuring three or more channels that include actigraphy,
oximetry, and peripheral arterial tone is covered when used to aid the diagnosis of OSA in
beneficiaries who have signs and symptoms indicative of OSA if performed unattended in or out
of a sleep lab facility or attended in a sleep lab facility.
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Outcome Studies• Several studies compared an HSAT algorithm to standard in‐lab testing
• For the most part those studies showed equivalence between HSAT and in‐lab PSG with regards to:
Patient satisfaction
Quality of Life
Epworth and other sleep measurement tools
CPAP adherence
• Caveat: Patients were chosen based on a high pretest probability
2007Published in 2007
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Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
Draft released on AASM website September 2016 available for public comment; revised and released Final in March JCSM
9 PICO questions addressed Patient/Population/Problem
Intervention
Comparison
Outcomes
Examined 7392 abstracts reviewed; 98 studies included in evidence base for recommendations (2005 start point) 86 included in meta‐analysis
Good Practice Statements:1. We recommend diagnostic testing for OSA be
performed in conjunction with a comprehensive sleep evaluation and adequate followup
2. We recommend PSG as the standard diagnostic test for the diagnosis of OSA in adult patients in whom there is a concern for OSA based on a comprehensive sleep evaluation
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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Recommendations:1. We recommend that clinical tools, questionnaires
and prediction algorithms NOT be used to diagnose OSA in the absence of PSG or HSAT (STRONG)
2. We recommend that PSG or HSAT with a technically adequate device be used for the diagnosis of OSA in uncomplicated adult pts presenting with signs and symptoms that indicate an increased risk of moderate to severe OSA (STRONG)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
Recommendations:3. We recommend that if a single adequate HSAT is
“negative”, inconclusive, or technically inadequate, PSG should be performed for the dx of OSA (STRONG)
4. We recommend that PSG, rather than HSAT, should be used for the diagnosis of OSA in pts with significant cardiorespiratory dz, potential respiratory muscle weakness due to a neuromuscular condition, awake hypoventilation or suspicion of sleep‐related hypoventilation, chronic opioid use, history of stroke or severe insomnia (STRONG)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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Recommendations:5. We suggest that if clinically appropriate, a split night
diagnostic protocol rather than a full night diagnostic protocol for attended PSG should be used for the diagnosis of OSA (WEAK)
6. We suggest that when the initial PSG is negative and clinical suspicion for OSA remains, a second PSG should be considered for the diagnosis of OSA (WEAK)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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Recommendations:1. We recommend that clinical tools,
questionnaires and prediction algorithms NOTbe used to diagnose OSA in the absence of PSG or HSAT (STRONG)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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STOP‐Bang Model1. Snoring: Do you snore loudly
(louder than talking or can be heard through closed doors)?
2. Tired: Do you often feel tired, fatigued, or sleepy during the daytime?
3. Observed: Has anyone observed you stop breathing during your sleep?
4. Blood Pressure: Do you have or are you being treated for high blood pressure?
5. BMI: BMI > 35 kg/m2?
6. Age: Age > 50?
7. Neck circumference: Neck circumference > 40 cm?
8. Gender: male?
Anesthesiology 2008; 108:812–21
High risk of OSA: answering yes to three or more itemsLow risk of OSA: answering yes to less than three items
Question #3What is the minimal length of time to run a home sleep apnea test for it to be considered adequate?
A.2 hoursB.3 hoursC.4 hoursD.5 hoursE.6 hours
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A. B. C. D. E.
8% 10%
53%
8%
23%
Question #3What is the minimal length of time to run a home sleep apnea test for it to be considered adequate?
A. 2 hoursB. 3 hoursC. 4 hoursD. 5 hoursE. 6 hours
Recommendations:2. We recommend that PSG or HSAT with a technically
adequate device be used for the diagnosis OSA in uncomplicated adult pts presenting with signs and symptoms that indicate an increased risk of moderate to severe OSA (STRONG)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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HSAT should be one which uses:
nasal pressure, chest and abdominal RIP, oximetryOR
PAT with oximetry and actigraphy
Note that a HSAT should have 4 hours of adequate recording
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
Recommendations:
3. We recommend that if a single adequate HSAT is “negative”, inconclusive, or technically inadequate, PSG should be performed for the dx of OSA (STRONG)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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HSAT
Less sensitive than PSG in detection of OSA
False negative could result in an untreated patient
Repeating a negative HSAT is likely to result in a second negative so recommended PSG; further, patient may not be inclined to repeat
Recommendations:4. We recommend that PSG, rather than HSAT, should be
used for the diagnosis of OSA in pts with significant cardiorespiratory dz, potential respiratory muscle weakness due to a neuromuscular condition, awake hypoventilation or suspicion of sleep‐related hypoventilation, chronic opioid use, history of stroke or severe insomnia (STRONG)
Clinical Practice Guideline for Diagnostic Testing for Adult OSA: An AASM Clinical Practice Guideline
Kapur V, et al; J Clin Sleep Med March 2017
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2017: Looking AHEAD
Physician Wo/Manpower Sleep Apnea
8% of US adult population (240,000,000) = 19,200,000
1% of US pediatric population (74,000,000) = 740,000
Total = 19,940,000
Insomnia 10% of US adult population = 24,000,000
Restless Legs Syndrome Estimate affects 12,000,000
TOTAL = 55,940,000 / 8000 BCSS = 7000 New Pts/yr
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Teaching Physicians about Sleep Medicine
Medical schools devote ~ 2 hours of teaching to sleep medicine (has not changed > 20 yrs)
Most residencies do not address sleep medicine topics other than sleep deprivation and fatigue; < 5% of board exams devoted to sleep medicine topics
83 Sleep fellowship programs – a full 40% of medical schools (147) do not have a sleep fellowship
Quantity and quality of fellow applicants is not of the highest quality for the NRMP sleep fellowship match
Numbers Game: Attracting medical students, residents and fellows to the field of sleep medicine
Teaching more sleep medicine in primary care specialties
Beyond Physicians: Education in other professional schools ‐nursing schools, NP programs, PA programs
2017: Looking AHEAD
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What’s Being Done To Improve This? AASM is trying to emphasize sleep medicine as a specialty
#Choose Sleep
SMIG – medical schools
Earmarking ASMF funding for research demonstrating the value of board certification in sleep medicine
Free attendance at annual meeting
Examine novel training requirements outside a formal 1 year sleep fellowship
Looking Ahead:Research funding
The average age at which an investigator with a medical degree receives their first R01 was less than 38 yrs old in 1980 – now more than 45 yrs old
More than twice as many R01’s are awarded to PI’s who are > 65 yrs old as are < 36 yrs old, a reversal from 15 yrs ago
NIH funding was cut for > a decade (2003)
In FY 2016, Congress raised the NIH budget by 5.9%
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Big Topics are Dementia, Cancer, Precision Medicine
Sleep is not likely to get independent funding and needs to “piggy – back” on these initiatives
Challenging to train sleep scientists – need novel funding streams for luring sleep fellows to a research tract
4 “T‐32’s” with a sleep emphasis
What’s Being Done To Improve This?
Affordable Care Act – New Administration promising to ?Repeal ‐ ? Replacement ‐ ? Repair
Declining reimbursements; increasing deductibles
Emphasis on Population Health
Increasing insurance (third party payor) impediments to delivering care
2017: Looking Ahead
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What’s Next? Insurance will move away from fee‐for‐service and will begin bundling payments
Population health is the BUZZWORD and since sleep disorders affect so many and result in comorbidity – we need to push those specialties to consider sleep disorders as part of the treatment
The Heart and OSA Atrial fibrillation
Up to 50% of afib patients have OSA
Treating OSA reduces rhythm conversion failure rates
Heart Failure 37% have OSA
Treatment of OSA improves cardiac function
Nontreatment of OSA increases risk of sudden death
Resistant Hypertension 70+ % have OSA
Treatment reduces BP med requirements
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Cardiology
Afib/EP pts
CHF
Resistant HTN
CAD
Endocrinology
Diabetes
Metabolic syndrome
Thyroid dz
Pulmonary
Asthma
COPD
Pulmonary HTN
Obesity hypoventilation
syndrome
Gastroenterology
GERD
Nonalcoholic Fatty Liver Dz
Sleep Specialist Nephrology
Microalbuminuria
Chronic kidney dz
ESRD
What’s Next Developing the Sleep “Team”
Develop a model of care in which PCP’s are paired with BCSS to help with training and oversight
HSAT in PCP offices – interpreted by BCSS
Followup care after initiation of treatment done by PCP
More training on sleep for APRN and PA’s
Developing on‐line educational modules
Using TELEMEDICINE to extend reach
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Telemedicine Successfully deployed in VA system
HSAT
CBT‐I
Reimbursement needs to catch up in order for sleep providers to adopt
Already successfully use telemedicine with CPAP adherence
Need sophisticated equipment – 2 way audio/video; secure data transfer; physical exam surrogate
What’s Next? Hypoglossal nerve stimulation and other neurostimulation therapies will continue to evolve and improve treatment options for other sleep disorders
Innovative technologies will continue to transform the way people regard their health
Smartphones and other wearables will diagnose sleep apnea and other sleep disorders
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Hypoglossal Nerve Stimulation
• Implanted device• Receives input from
sensing lead to time delivery of stimulation to nerve with onset of inspiration
• Outcome (STAR Trial): Reduced AHI by 68%;
29.3 to 9.0 Therapy maintenance
group showed sustained reduction
Now FDA approved and covered by many insurances
Looking Ahead:Technology
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Tracking Sleep and Beyond
Current Technologies Sleep diaries and logs
Smartphones with/wo sensors Passive monitoring of audio (snoring, sleep talking), sleep debt analysis, sleep latency
Active apps/devices Modify sleep/dreams with audio
Manage wake times with “smart alarms”
Facilitate relaxation
Prevent falling asleep away from your bed
Modify environment (temp and light)
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Current Technologies Smartphones
Sensors
Wearables
Wrist
Headband
Chest band
Eye mask
Ear piece
ankles
Question #4Most commercially available “sleep sensors” compared to polysomnography:
A. are usually accurate within 10 minutes of total sleep time
B.tend to overestimate total sleep time by more than 30 minutes
C.tend to underestimate total sleep time by more than 30 minutes
D.are well validated
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A. B. C. D.
5%
67%
24%
5%
Question #4Most commercially available “sleep sensors” compared to polysomnography:
A. Are usually accurate within 10 minutes of total sleep time
B. tend to overestimate total sleep time by more than 30 minutes
C. tend to underestimate total sleep time by more than 30 minutes
D. are well validated
Current Technologies: Are these helping or hurting us?
Benefits More interest in their sleep!! Motivate to improve
Modest agreement with PSG
Disadvantages Modest agreement with PSG
Of the 80 devices; 7 have FDA approval, 3 are used by NASA, 1 has been validated in a sleep trial
Have to sleep in a standard bed
Privacy risks
Competition – disappear from the market
May disrupt sleep
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Sleep Fellow Project
To determine the accuracy of 4 consumer sleep tracking devices
Methods: A nonrandomized prospective study of four consumer sleep tracking devices compared to PSG in patients in the Emory Sleep Lab undergoing diagnostic testing
Goal: 10 subjects for each device
Data CollectedParameters: Hypnogram
Sleep onset latency
Total sleep time (TST)
+/‐ Deep Sleep
+/‐Wake after sleep onset (WASO)
+/‐ Sleep score
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Gear4 Renew Sleep ClockThe Lark
Axbo ClockSleepTrackerWatch
SummaryParameters LARK Axbo Sleeptracker GEAR4 Average
Sleep onset latency 12.4 22.2 9.6 5.3 12.375Total sleep time 48.2 93.3 52 52.4 61.475Deep Sleep 26.2
WASO 36.8
1 2 3 4 5 6 7 8 9
SleepTracker 372 389 478 376 459 406 434 416 451
PSG 345 313 412 358 394 384 367 382 358
0
100
200
300
400
500
600
Min
utes
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20 subjects – no history of sleep disorders
Download app (Azumio) then used at home for 5 nights (so app can become acclimated)
Underwent PSG study and questionnaire
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Picture This:
Time For Bed
68⁰69⁰
70⁰71⁰
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Using Consumer Technology to Diagnose Sleep Disorders
Few validation studies
Direct to consumer (Walmart/Walgreen model):
Screening devices → take to their provider
May increase interest in their health
Must decide what to do with the information
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50 subjects (10 for development, 40 for validation)
Variable degrees of OSA
Smartphone taped to chest while undergoing diagnostic PSG
Measured “sound power dips (SPD)”: dip in given threshold last < 90 secs with descending and ascending portions steeper that the threshold values per 18 sec
Smart RDI = SPD/hour of test
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Smartphone App for SnoringLimitations:
tested in sleep lab environment
No bedpartner or pets
Little ambient noise
Tested on patients referred for sleep apnea
Not very accurate for mild – moderate OSA
Positive aspects Easy and lots of people have them
Technology will improve
More patients identified
Validation study of 62 ptsSimultaneous with PSGSensitivity 88%; Specificity 91%
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Summary Sleep Medicine has come a long way in the last 25 years: bonafidespecialty with certification exam, training programs, research centers, accreditation, meetings, journals, books
Biggest challenge is being able to manage the large volume of patients with sleep disorders in a system that is undereducated about sleep
Testing in the home will expand beyond sleep apnea and sleep knowledge among healthcare consumers will continue to grow