Presentazione di PowerPoint · Months y 0 60 120 180 240 300 0.0 0.2 0.4 0.6 0.8 1.0 Halsted (349)...
Transcript of Presentazione di PowerPoint · Months y 0 60 120 180 240 300 0.0 0.2 0.4 0.6 0.8 1.0 Halsted (349)...
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Umberto
Veronesi
presentado por
Roberto Orecchia
Director Scientifico
IEO in Milan & CNAO in Pavia
5th November 2017
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On November 8th,
we lost
a visionary and true
gentleman
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During his long and
productive life,
he made significant
contribution
to surgical science,
to cancer care and
prevention, and
to medical education
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From
Maximum tolerable
treatment
New Paradigm
To
Minimum effective
treatment
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The Breast
model
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ABVD
CMF
In Milan
the hystory
of breast
cancer
changed
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….. In the italian study, begun in 1973 by Dr Umberto Veronesi …..
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Months
Pro
bab
ility
0 60 120 180 240 300
0.0
0.2
0.4
0.6
0.8
1.0
Halsted (349)
Quadrantectomy + RT (352)
1981; Milan I trial - Survival
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Milan
Trial
0
1990
x 1
000
50
100
150
200
250
1980 2000 1990
NSABP
Trial
300
350
2010
Radical Mastectomy
Breast Conserving Surgery
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• Radiotherapy after breast-conserving surgery in women with localized cancer of the breast (N Engl J Med, 1993)
• Avoiding axillary dissection in breast cancer surgery: a randomized trial to assess the role of axillary radiotherapy (Ann Oncol, 2005)
• Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): a randomized controlled equivalence trial (Lancet Oncol, 2013)
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CNAO – Pavia – May 2001
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III
II
I
Sentinel Node Biopsy in Breast Cancer
European Institute of Oncology (1996 - 2017)
Radiotherapy after breast-conserving surgery in women with localized cancer of the breast
(N Engl J Med, 2003)
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Follow-up (years)
Pro
po
rtio
n o
f p
ati
en
ts s
urv
ivin
g (
%)
Sentinel-lymph-node biopsy as a staging procedure in breast cancer: update of a randomised
controlled study (Lancet Oncol, 2006)
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• Science for the Peace
• Future of Science Conventions
• European School of Oncology
• EUSOMA
• EURAMA
• AIRC
• European Institute of Oncology
• Umberto Veronesi Foundation
• Europa Donna
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• International Society of Cancer Chemoprevention
• Committee of Cancer Expert of the European Union
• International Union Against Cancer
• Federation of the European Cancer Societies
• EORTC
• International Group for Melanoma
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And in 2014 he passed the torch
Many Thanks, Umberto !