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Definition of LPT

LPT is the abbreviation for Laser Photo Therapy, which means the treatment of symptoms like pain, inflammation or wound healing with non-thermal laser radiaion, LPT is used in various fields like: Pain / inflammation: Wound healing: - Arthrosis - Burns - Epicondylitis - Scars / Keloids - Carpal Tunnel Syndrom - Ulcus cruris - Diabetic foot Sport Injuries: Others: - Luxation - Tinnitus - Distortion - Acne - Fracture - Facial Paresis - Shoulder-Arm-Syndrom - Zoster

Example on tissue regeneration

After 2 weeks

Accelerated wound healing

History of LPT

In 1963 Endre Mester performed the first trreatment of lasers on mice. He found a stimulation of hair growth on the treated spots.* In later studies he found also an increased epithelization of wounds.** * Endre Mester, B.Szende u.a.: The effect of laser beams on the growth of hair in mice. In: Radiobiol Radiother. 9/1968, S.621-626 ** Endre Mester: Laser - induced stimulation of the vascularisation of the healing wound. In: Separat.Exp. 30/1974, S.341-345

Scientific Evidence

Is there scientific evidence for LPT? The answer is clearly: YES - More than 3000 scientifical and clinical publications listed in PubMed* - More than 160 randomized placebo controlled double blind studies** * **: December 2011

Different lasers for different indications:

Tatoo & hair removal – 694 nm Ruby laser (crystal)‏

Hair removal, bone cutting – 755 Alexandrite (crystal)‏

Tumor coagulation – 1064 nm NdYAG (crystal)‏

Kidney stone treatment – tunable (liquid dye laser)‏

Eye surgery – 193 nm, 248 nm, 308 nm Excimer laser (gas)‏

Dermatology – 10.600 nm CO2 laser (gas)‏

Biostimulation: LaserCat / PalmLaser / SilkLite

HeNe: 633 nm red (gas)‏

InGaAlP: 630 nm – 685 nm red (semiconductor, diode)‏

GaAlAs: 780-820-870 nm IR (semiconductor, diode)‏

GaAs: 904, 905 nm IR (semiconductor, diode)‏

Different laser types used in medicine

A laser emits a special sort of light which is

monochromatic (only one colour ==> highest power intensity)

and

• coherent (all waves oscillate parallel to each other)‏

Biophotons of the body emit also

coherent light*

Wave peaks and wave troughs are parallel to each other

* Prof. Dr. Fritz-Albert Popp,

Int. Institute for Biophysics, Neuss

www.biophotonen-online.de

Laser Light and Biophotons

The meaning of coherency

Non-coherent light

Coherent light

UV – Visible - IR

UV – Visible - IR

Wavelength dependent treatment depth

Visible light UV light

x-rays Cosmic radiation

IR light

Thermal radiation

TV Radio

** *

Spectrum of radiation

MedSolution LPT devices:

‏of‏combination‏:Wavelength‏•

red* & infrared**

Red: for indications on the surface infrared: for deep laying indications

Spectrum and Penetration depth

Treatment depth versus treatment time

Mitochondria

ATP (Adenosine-Tri-Phosphate): the molecular energy for each cell of the body and the skin.

It is built in the mitochondria, the power station in each cell. The light is absorbed by components of the cellular respiratory chain namely cytochrome c oxidase (COX).

If there is too less ATP available, the cell cannot follow its functions 100%

LaserCat & PalmLaser bring energy to the mitochondria where it is used to produce more ATP - which means new energy for the cell.

Regeneration of the cell, the tissue and the body can be seen already after a few treatments.

The ATP synthesis

• LPT increases the ATP synthesis min 150 %

==> biostimulation / regeneration of tissue

==> reduction of inflammation

==> relief of pain

regeneration‏tissue‏improved‏<==‏production‏collagen‏the‏stimulates‏LPT‏•

‏,oxygen‏more‏,nutrients‏more‏<==‏metabolism‏and‏flow‏lymphatic‏,flow‏blood‏the‏supports‏LPT‏•

more blood cells are available for an increased healing and regeneration, swellings are reduced

RNA-, DNA- & protein synthesis ==> improved cell regeneration‏the‏stimulates‏LPT‏•

Biochemical effects

Enhancement of ATP production

Arndt-Schultz-Law

Biphasic dose response in measured difference in integrated area under the curve of time course of wound size compared to no treatment control, with a clear maximum seen at 2 J/cm2, and the high dose of 50 J/cm2 gave a worsening of the wound healing time *Dose Response. 2009; 7(4): 358–383. Published online 2009 September 1. doi: 10.2203/dose-response.09-027.Hamblin, PMCID: PMC2790317 Biphasic Dose Response in Low Level Light Therapy Ying-Ying Huang, Aaron C.-H. Chen, James D. Carroll, Michael R. Hamblin

Pain versus time

Pain

Time

Effects on wound healing

- Enhanced DNA and RNA synthesis * - Stimulation of mitosis ** - Accelerated tissue regeneration *** * M.Dyson, S.Young: Effect of laser therapy on wound contraction and cellularity an mice. In: Lasers Med.Sci. 1/1982, S.125-130 * Tiina Karu: Molecular mechanism of the therapeutic effect of low-intensity laser irradiation. In: Lasers Life Sci. 2/1988, S.53-74 * V.Manteifel u.a.: Activation of transcription in lymphocytes after exposure to a He-Ne laser. In: Mol.Biol. 24/1990, S.860-867 *,G.Danhof: Biological effects of the laser beam. In: Lasers in Medicine and Dentistry. Zagreb 2000, S.127-152 ** Tiina Karu: Mechanisms of Low-Power Laser Light Action on cellular Level In: Lasers in Medicine and Dentistry.Zagreb 2000, S.97-125 ** O.A. Tiphlova und Tiina Karu: Role of primary photoacceptors in low-power laser effects:action of He-Ne Laser radiation on bacteriophage T4 - Escheria coli interaction. In: Lasers Surg.Med. 9/1989, S.67-69 *** N.Ben-Dov. u.a.: Low-energy laser irradiation affect satellite cellproliferation and differentiation in vitro. In: Biochem.Biophys.Acta. 3/1999, S.372-380 *** A.Mester u.a.: Open wound healing - bed sores, ulcus cruris, burns - with systemic effects of LLLT. In: Lasers in Medicine and Dentistry. Zagreb 2000 *** V.d.Veen, P.Lievens: Low level laser therapy (LLLT): the influence on the proliferation of fibroblasts and the Influence on the regeneration process of lymphatic, muscular and cartilage tissue. In: Lasers in Medicine and Dentistry. Zagreb 2000, S.187-217

Dental Medicine Acid & Grinding Trauma Aphtae

Dentitio difficilis

Extraction wounds Lockjaw Nausea Paradontosis Stomatitis Temporomandibular- jaw

pain Dental root hyper- sensibilities

Dermatology / plastic surgery

Abrasions

Acute injuries

Allergies

Burns

Decubiti

Fresh scars & keloids

Hematoma after surgery

Herpes Zoster, H.

Labialis

Post surgical pain

Ulcus Cruris

Urticaria

Wounds

General Medicine Acute injuries

Arthrosis

Gout

Neuralgiform pain

Panarteriitis

Tinnitus

Trigeminusneuralgi

a

Wounds

Orthopaedics Carpal Tunnel Syndrome

Distortion

Epicondylitis

Fibromyalgia

Ischialgia

Lumbago

Muscular Induration

Post surgical pain

Shoulder-Arm-Syndrome

Application in Medicine - examples

Patientes with cardiac pacemaker in the area of the thorax Pregnant women in the area of the abdomen Patients with cancer Skin diseases without diagnose Epilepsy patients no radiation on: Open eyes Thyroid gland Solar Plexus Child's epiphysis Open fontanel of infants

Contraindications / Precautions

The Laser Photo Therapy has only very few side effects:

The treatment effect can be:

• A little tingeling in the treated area

• A warm feeling in the treated area (blood flow!)‏

• A higher sensitivity in open wounds

• If too much energy is used, a surpressing effect can take place

Further there can be

• Some tiredness

• Increased sweating

Side effects

Why should I start using LPT – New Paradigma

Very broad indication range of LPT

&

No or negligible side effects

- >

Trade off between beneficial effect and side effects always in favour of treatment

- >

Therapy possible without secure diagnosis

Eye protection

Parallel laser beams are of great danger for the

eyes. The beam can be focused by the eyes and

damage the retina irreparable ! (Class 3b & 4

lasers)‏

Laser light which is coming through the closed

eyes is not dangerous as the light is not focused, it

is diffuse.

PalmLaser are class 1M lasers and emit a

divergent beam, which becomes only danger, by

looking into it directly for more than 100 seconds.

A divergent beam can not be re-focused by the

eyes. Therefore PalmLaser are much safer than

class 3b lasers.

There are no precaution actions necessary for a

class 1M laser.

Safety considerations

PalmLaser: combination of cw lasers

red & IR

Power in mW

Time in nsec

Laser 1 Red laser 650 nm, 20 mW cw = continuous wave

Power in mW

Time in nsec

Laser 2 IR laser 785 nm, 80 mW cw = continuous wave

Specification of PalmLaser

Laserclass 1M: No protection goggle No laser safety course No special precautions required

PL - Safety

•If the red battery control LED lights up, PalmLaser needs to be charged. There are approx 5 minutes left to finish the treatment.

•During charging PalmLaser, a green LED lights up till the charging process is finished.

Charging time - approx. 3 h Treatment time - approx. 1 h

PalmLaser

PalmLaser / PalmLaser professional comes with the following accessory:

•PalmLaser

•Operation manual

•Battery charger

•Case

•Accumulators (inside PalmLaser)‏

PL & PL professional - accessories

Muscle-lesions‏•

Edema‏•

Swellings‏•

Bursitis‏•

Tendinopathies‏•

Tenosynovitis‏•

Distortions, contusions, sprains‏•

Capsulo-ligamentar lesions‏•

Abrasions‏•

Fractures‏•

‏runner‘s)‏syndrome‏band‏Iliotibial‏•

knee)

Traumas‏•

Arthrosis‏•

Rheumatoid arthritis‏•

Myalgia‏•

Decubitus ulcers, Pressure sores‏•

Circulatory disorder‏•

Diabetic foot‏•

Ulcus cruris, Leg ulcers‏•

Back pain‏•

Shoulder-arm-syndrome, Frozen‏•

shoulder

Tension, stiffness‏•

Carpal-tunnel-syndrome‏•

Fall-related injuries‏•

PL & PL professional - Application

Application

CTS Knee Shoulder

Head

Application

Application

Application

The application is as easy as with LaserCat. After adjusting the time due to the recommendations in the manual Or against own experience, the diffusor can be set on the skin and The treatment can be started. The diffusor shall stay in contact with the skin to avoid too much loss by reflections. Exception: open wounds. PalmLaser shall be moved slowly over the complete area.

Dr. Rarreck, FC Schalke 04

Jörg Blüthmann, Physiotherapist, Hertha BSC Berlin

PalmLaser– Application Dr. Rarreck

PL– Application Schalke 04

PL – Application Schalke 04

PL– Application Schalke 04

Self-Treatment

Veterinary use

Easy operation

Two wavelength in one machine

Class 1M laser

Pre-set program in LaserCat

Mobile use with PalmLaser & SilkLite

No protection goggle needed

No harm to the skin/tissue, no heat

For acute & chronic diseases

Advantages of LPT with LaserCat & PalmLaser

patients 2-3‏with‏already‏profitable‏Highly‏•PalmLaser delivers highly effective laser- phototherapy and represents a lucrative proposition to professionals. Performing regular therapy sessions on 2 -3 patients per month breaks the threshold of profitability. tool‏acquisition‏and‏loyalty‏Patient‏•Offering and delivering effective and safe innovative therapies elevates the image of the practice, leading to long term patient loyalty and patient recommendation based increase in popularity. potential‏full‏the‏to‏assistant‏your‏Using‏•PalmLaser treatment is easy to perform and can be delegated to less qualified, but well trained‏assistants,‏thus‏freeing‏the‏valuable‏doctor‘s‏time‏for‏other‏duties‏and‏tasks. The assistants can dedicate more time to the patients, thoroughly explaining the thera- py and providing as much personal care and attention as the patients desire. Further the motivation and qualification of the assistant will increase. systems‏therapy‏your‏Enhancing‏•Ability to perform laser-phototherapy guarantees a real USP advantage for your practice. Despite its proven efficacy and safety, laser-phototherapy is not yet widely spread due to the past difficulties with early lasers (i.e. complexity, size and high costs). PalmLaser from MedSolution provides a practical and affordable solution to the pro- blems of the past, making laser-phototherapy accessible, affordable and well within your reach! As a part of modern therapeutic approach PalmLaser is an effective and safe therapeu- tic solution to many health problems.

Advantages for the doctor´s

practice using LPT

efficient‏Highly‏•PalmLaser delivers highly powerful and potent laser therapy for acute or chronic medical conditions. PalmLaser supports an array of healing processes at cellular level and signifi- cantly accelerates regeneration. Pain and inflammation reduce swiftly. highly efficient treatment method –‏effects‏side‏No‏•Today‘s patient is well informed and demands interventions that are effective,safe and without side effects or treatment related harms. Therapy with PalmLaser is safe and pain- less. Side effects have never been noted. PalmLaser is a stand alone therapeutic modality or can be used in synergy with other therapies, such as physiotherapy or prescription medicines. In some conditions, PalmLaser can entirely replace or largely reduce the need for other therapeutic interventions. recovery‏Fast‏•Laser-phototherapy helps athletes to return to training or competition faster or without excessively long delay. Portability of PalmLaser allows the treatment to commence immediately after the trauma has occurred – The immediate post trauma application of laser therapy is the most effective way of dealing with injuries for optimum healing and fast recovery. self-healing mechanisms‏somatic‏the‏supporting‏for‏therapy‏Premium‏•Laser-phototherapy is a natural and modern therapy that is recognised and appreciated by many people. Older and the elderly patients in particular value the features and the benefits of laser-phototherapy. Laser-phototherapy is effective, yet gentle and non-trau- matising. It activates self healing, regeneration and restoration. Improvements achieved with PalmLaser phototherapy can be life changing and giving new leases to

Advantages for the patient using LPT

LaserWorld Guest Editorial, Nr 13 - 2000.

The mangement of diabetic neuropathic

ulceration by HeNe laser.

The following photo sequence has been contributed by Dr.

Ali Abaci, Turkey

The main effects of the LLLT helps the patient in terms of

-> skin regeneration

-> wound healing

-> blood circulation

Treatment parameters for the diabetic neuropathic ulceration are given below : He-Ne Laser,

wavelength 632 nm. Continuous Wave Beam Area(cm2)= Diameter(cm)2 x 0.7854 = (3.1 x 3.1)

x 0.7854 = 7.547 cm2 Laser Output Power = 5 mW= 0.005 W Laser Output Power(W) Power

Density(W/cm2)= Beam Area(cm2) 0.005 == 0.0006625 W/cm2 7.547 Energy Density(J/cm2)=

Power Density(W/cm2) x Time(sec) = 0.0006625 x 600 = 0.3975 J/cm2 = ~ 0.4 J/cm2.

Treatments were given once a day, 5 days a week, totally for 4 weeks

Example – diabetic foot ulcer

Example – Diabetic Foot Surgery I

Chief Surgeon & SAFDAP: Dr. Abdulazizi Al-Qannass Podiatry Surgery Team – Riyadhh: SAFDAP Assistant Ms. Jazwa Al-Otaibi Mr. Matthew Mallon Mr. Mumdoh Mnwar

Case: 42 old Male, suffering from Obesity and Diabetic Type II. Come to the clinic with highly affected toe in the right foot, amputation needed for the fifth toe. On medication Hypo Glacimic, after amputation started on Insulin. Foot after fourth session with PalmLaser: Pus from tunnel wound Dry tissue and dark color Wound is closing

Example – Diabetic Foot Surgery II

The after amputation wound was under treatment with antibiotic for 3 months, wound did not heal and foot skin color was dark and did not get well, the patient was under stress and pain.

Low Level Laser Therapy was decided to be applied by PalmLaser, 5min, each session, day after day, 3sessions per week. The time frame of treatment set to 30 Days. Foot afer 13 sessions with PL: Tissue and skin heal from necrotic stage. Wound completely heal from infection and wound is close with no pain. Foot tissue and blood circulation are back to normal.