Larynx Class Slides

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    Unit5:Anatomyandphysiology

    ofLarynx

    1

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    inneckalongwithassistancefromstructures

    .

    Un t5:Stu yt eanatomy p ys o ogyan diseasesofthelarynx.

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    Larynx,commonlycalledVOICEBOX

    Locatedinfront,inthemiddleofthe.

    Perchedontheto ofthetrachea(windpipe).

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    5

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    withage,gender,headpositionand

    .

    The

    length

    of

    larynx

    is

    about

    44

    mm

    in

    an

    .

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    Biologicalfunctions

    Buildingintrathoracicpressureforexcretion

    an carry ngou s renuousp ys ca ac v es

    Nonbiologicalfunctions

    S eech

    Singing

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    Madeofabone,cartilages,muscles,

    .

    Hyoidbonesupportslarynx.

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    Ushapedsinglebone presentabovethethyroid

    .

    ssuspen e rom e pso

    Styloid processes

    of

    the

    Temporal

    .

    Itisnotconnectedtoanyotherbonedirectly.

    Hyoidboneissupportedbymanymuscles&it

    canmakevarietyofmovements. 9

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    Hyoidhas3parts:abodyand2pairsofhorns.

    theThyroidcartilage.

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    NOTE:ligamentvs.cartilagevs.

    tendon Ligament:Fibroustissuethatconnectsbonestoother

    .

    Cartilage:Stiffyetflexibleconnectivetissuefoundin,

    bones.Itisnotashardandrigidasbonebutisstifferand

    lessflexiblethanmuscle.

    Tendon:Toughbandoffibrousconnectivetissuethatusuallyconnectsmuscletoboneandiscapableof

    withstandingtension.Tendonsaresimilartoligaments

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    3unpaired&3pairedcartilagesinlarynx.

    um er

    Epiglottis single Behind the hyoid bone and base of the

    Thyroid single Front of the neck in the midline

    Cricoid single Above the trachea; below thyroid cartilage

    Arytenoids paired Rests on the back surface of cricoid

    cartilage

    orn cu ates pa re ests on t e aryteno cart agesCuneiform paired Embedded in aryepiglottic folds

    14List of cartilages & location in larynx

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    Itisleafshapedcartilage.

    Attac e toupper,inner

    surfaceofThyroid.

    ItattachestoArytenoidsat

    thebackbythe

    Quadrilateralmembrane.

    Theu ermar insare

    formedbytheAryepiglottic

    olds.

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    food,water,salivaintotrachea.

    swallowing.

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    Biggestcartilageinlarynxpresent

    .

    Protectsvoiceboxinthefront.

    2laminas(quadrangularplatesof

    cartilage1onrightside&1on

    leftside)

    Laminas oinatmidlinetoform

    thethyroidprominence(Adams

    a leinmen Feltorseenon

    17

    surfaceoftheneckinmostmen.

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    Thyroid(Cartilage)

    2bighornlikestructures(greaterorns toattac tot e yo one.

    2smallhorns(lesserhorns)to

    attachmentwithCricoidcartilage.

    LesserhornsattachTh roidtoCricoid

    throughtheCricothyroidligament&

    Cricoth roid CT oints.CT ointsare

    importantforchangingthepitch.

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    Itforms baseoflarynx.

    ac e o yro a ove roug Cricothyroidligament,Cricothyroidjoints

    rac ea e ow y r co rac ea

    ligament.

    Ringshapedcartilage

    Frontsurfaceisthin,narrow(calledArch)

    &backsurface(knownasLamina)is

    broad,thickandwide. Arytenoidsare

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    presentonthelaminaofCricoid

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    Thesearepaired,pyramidshapedcart agespresentonupper

    marginsoflaminaofCricoid

    cart age.

    EachArytenoidhasabase,anapex&3surfaces.

    Vocal rocess resentonthe

    medialsurfaceisanimportant

    structure,becausethe formthe

    20

    posterior1/3rd oftruevocalfolds.

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    Arytenoidsareattachedto

    VestibularandVocal

    .

    They

    are

    attached

    to

    Cricoid

    t roug t eCricoarytenoi

    ligaments&joints.

    Theseligaments&jointsareimportantfortheopening&

    closingofvocalfolds.21

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    Corniculates:Small,paired,nodularstructures

    .

    Theymaybe2orevenabsentsometimes.

    Cuneiform:Small,paired,rodlikestructurespresentabovetheCorniculates.

    Presentinafewindividuals

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    Bronchial Tree Model - Larynx - Sagittal View.flv

    24

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    Joints/ligamentsoflarynx ar agesareconnec e oeac o erw e

    helpofjoints,musclesandmembranes.

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    Joints/ ligaments Connects Action

    Cricothyroidligament and joints

    Thyroid toCricoid

    Helps in changing the pitch ofvoice

    Cricoarytenoid joints

    and ligaments

    Cricoid to

    Arytenoid

    Important for opening and closing

    of vocal folds

    Vestibular ligaments Arytenoids

    to Thyroid

    Helps in changing the pitch of

    voice

    Vocal ligaments Arytenoidsto Thyroid

    Helps in changing the pitch ofvoice

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    voice(sound)arethevocalfolds.

    Truevocalfolds.

    T eirmain unctionisprotectiono t e owerairway.

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    Ventricularfolds/FalseVocal

    Folds

    withveryfewmuscles,bloodvessels&nerves.

    (insert)tothearytenoidscartilagesattheback

    .

    Notsuitedforvoice productionastheyarebulky

    an onot avemanymusc es, oo vesse san nerves.

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    TheyarepresentjustbeneaththeVentricularfolds.

    eyor g na e rom e yro car age, n e

    frontandinsertintotheArytenoidcartilagesatthe

    ac roug e oca gamen s.

    The

    true

    vocal

    folds are

    light

    pink

    in

    color

    but

    on

    laryngoscopyappearglossywhitebutthecolor

    changesinclinicalconditions.

    Thespacebetweenthetruevocalfoldsiscalledthe

    Glottis.

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    VFsaremadeofmucousmembranes,ligaments&

    .

    Undermicroscope,5differentlayerscanbe

    en e :

    1. Epithelium2. SuperficiallayerofLaminapropria (Reinkes

    space)

    3. IntermediatelayerofLaminapropria

    .

    5. Vocalis muscle 30

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    TrueVocalFolds/Vocalfolds

    Crosssection

    view31

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    " "

    anditiscontinuouswiththeliningofmouth,

    .

    Laminapropria as3 istinct ayers,eac wit adifferentconsistency.TheIntermediatelayerand

    eep ayero am na ropr a ormst e oca ligament.

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    ,

    surface

    , ,

    likerubberbands

    Deep ayer at rea i eco agenous i er ayer

    Vocalismuscle isthemainbodyofthevocalfold

    andverystiff.

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    superior&inferiorthyroidarteries andcricothyroid

    .

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    (i)Superiorthyroidartery

    ranc ranc o esuper or yro o esuper or yro artery(branchoftheexternalartery(branchoftheexternal

    entersentersthelarynxthroughthethelarynxthroughthe

    withtheinternalbranchofthewiththeinternalbranchofthe

    ri r lar n al n rvri r lar n al n rv

    mucousmembranesinthemucousmembranesintheri r rti n f th lar nxri r rti n f th lar nx

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    thyroidartery(thyroidartery(thyrocervicalthyrocervical trunkofthetrunkofthesubclaviansubclavian

    AscendsAscendsonthetrachea,togetherwiththeonthetrachea,togetherwiththe

    ,,

    fromlowerbordersfromlowerborders

    upp esupp est emusc esan mucousmem ranes nt emusc esan mucousmem ranes nthelowerpartofthelarynxthelowerpartofthelarynx

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    38Figure in SLM

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    BranchBranchofthesuperiorofthesuperior

    PassesPassesacrossthesuperioracrossthesuperior

    portiono t eportiono t ecricot yroicricot yroi

    ligamentligament

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    drainedbyvesselswhichaccompanythesuperior

    ,

    andemptyintotheupperdeepcervicallymph

    Whereasthezonebelowthevocalfoldsdrains,

    .

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    ADDITIONALINFORMATION

    VENOUSDRAINAGEVENOUSDRAINAGE

    superiorandinferiorlaryngealveinssuperiorandinferiorlaryngealveins (followthearteriesintheircourse)(followthearteriesintheircourse)

    superiordrainagesuperiordrainage joinsthesuperiorandmiddlethyroidveinsandthenthejoinsthesuperiorandmiddlethyroidveinsandthenthe

    internaljugularinternaljugular inferiordrainageinferiordrainagejoinsthemiddlethyroidveinandtheinferiorthyroidvein,joinsthemiddlethyroidveinandtheinferiorthyroidvein,

    whichemptiesintothesuperiorvenacavawhichemptiesintothesuperiorvenacava

    LYMPHATICDRAINAGELYMPHATICDRAINAGE

    larynxwellsuppliedwithlymphatics,withtheexceptionofthefreemarginsofthelarynxwellsuppliedwithlymphatics,withtheexceptionofthefreemarginsofthe

    vocalfoldsthemselvesvocalfoldsthemselves

    SuperiorgroupSuperiorgroup

    area of the lar nx above the vocal cords is drained into the su erior and middlearea of the lar nx above the vocal cords is drained into the su erior and middle

    jugularnodesjugularnodesInferiorgroupInferiorgroup

    nodesaswellastotheparatracheallymphnodes.nodesaswellastotheparatracheallymphnodes.

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    ItisfromtheVagusbywayofitssuperiorandrecurrentlaryngealbranches. Itdescendslateraltothepharynx,behindtheinternalcarotid,supplytothe

    cricothyroid

    muscle,

    divides

    into

    two

    main

    sensory

    and

    motor

    branches.

    Externallaryngealnerve suppliesthemucousmembraneofthelowerpartofthehar nx e i lottis valleculaandvestibuleofthelar nx ar e i lotticfold mucous

    membranedowntothelevelofvocalfolds.

    Internallaryngealnerve alsocarriesfibersfromneuromuscularspindlesandotherstretchreceptorsinthelarynx.

    Suppliestheinferiorconstrictormuscleofthepharynx,anduniteswithanascendin branchoftherecurrentlar n ealnerve. ThisbranchiscalledGatens

    anastomosis

    or

    loop

    and

    is

    purely

    sensory

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    recurrent(inferior)laryngealnerve ontherightsideleavestheVagusasthelattercrossestherightsubclavianarteryand

    thenloopsunderthearteryandascendstothelarynx,betweentheoesophagusandtrachea

    Thenervethendividesintomotorandsensorybranches

    Themotorbranchsupplyalltheintrinsicmusclesofthe.

    Thesensorybranchsuppliesthelaryngealmucousmembranebelowthelevelofthevocalfoldsandalsocarriesafferent

    ers romstretc receptors nt e arynx.

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    Laryngeal membranes Location

    Epithelium)

    r covoca mem rane onus

    Elasticus)

    r g na es rom r co car age

    and connects the Cricoid, Thyroid,

    and Arytenoid cartilages together.Inserts into the true vocal folds

    Quadrangular membrane Connects Epiglottis and Thyroid to

    e ry eno car ages a e

    back

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    surroundingstructures. Intrinsicmuscles

    .

    Muscle Origin Insertion Action

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    Posterior

    cricoar tenoid

    Back surface of

    Cricoid lamina

    Back surface of the

    muscular rocess of

    opens the glottis by

    o enin the vocal folds

    (PCA) Arytenoids

    Lateral

    cricoarytenoid

    upper border of the

    Cricoid arch

    Front surface of the

    muscular process of the

    closes the glottis by

    closing the vocal folds

    (LCA) Arytenoids

    Cricothyroid(CT)

    Front and sides ofthe Cricoid arch

    Thyroid lamina andlower horns of thyroid

    Increases the lengthand tension of the vocal

    folds

    Vocalis inner surface of the

    Thyroid

    Front surface and vocal

    process of Arytenoid

    Increases tension of

    vocal folds

    Transverse

    arytenoid

    Muscular process

    of one Arytenoid

    Muscular process

    of the opposite

    Ar tenoid

    closing the vocal folds

    Obliquearytenoid

    Muscular processof one Arytenoid

    Muscular processof the opposite

    Arytenoid

    closing the vocal folds

    Thyroarytenoi

    d

    inner surface of the

    Thyroid

    Front surface and vocal

    process of Arytenoid

    Relaxes the vocal folds

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    Includes

    1 respiratoryo struction

    2) Stridor

    3) weakenedorabnormalcry,

    5) Tachypnea (rapidshallowbreaths)

    6 Aspiration7) episodesofcyanosis(bluecolorationdue

    deoxygenatedhemoglob)

    8 suddendeath.48

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    Highpitchedsoundresultingfromturbulent airflow

    .

    Indicativeofseriousairway obstructionfromsevere

    con onssuc asep g o s,a ore gn o y.

    Duringfetaldevelopment,thestructuresinthe

    larynxmaynotfullydevelop.

    Stridorisindicativeofapotentialmedical

    emergency andshouldalwayscommandattention Itcanresolvesonitsown withoutmedical

    intervention(apparentuntilabouttheageof5)49

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    commonanomaly(causeisunknown)

    structuresoninspiration

    Stridorduringinspirationwhich

    worsensinthesupineposition,

    feeding,agitationwithNormalPhonation

    Thesymptomsmayincreasebutusuallyresolvesby

    Tracheotomy

    in

    place

    for

    2

    years

    spont.

    recovery50

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    Symptomsvarydependingonwhetherunilateralor

    bilateralvocalcords aral zed.

    BilateralVCparalysis:CNS immaturity,lesionsin, , .

    Symptoms:

    nsp ratorystr oratrestt atworsensupon

    agitationinchildren

    Progressiveairwayobstruction

    Aspirationsresultinginrecurrentchestinfections

    andafailuretothrive51

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    UnilateralVocalCordParalysis:usuallyidiopathic,

    ,

    totheleftrecurrentlaryngeal.

    n a era para ys smayman es ur ng e rs

    fewweeksoflife,oritmaygounnoticed.

    Symptoms:

    Hoarse,breathycrythatisaggravatedbyagitation,

    Feedingdifficulties

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    Incompletedevelopmentduringthethirdmonthof

    subglotticstenosis

    Symptoms

    Respiratory

    stridor

    (duringinspiration&expiration)

    Cryisusuallynormal

    Prognosisisusua ygoo . Mostsymptoms a eas

    thebabymatures.53

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    rarecongenitalanomaliesduetoIncomplete

    thirdmonthofgestation.

    Symptoms:

    Stridor

    Aphonia,ormildhoarseorbreathycrythatis

    aggravatedbyagitation Feedin difficulties

    Aspiration &Obstructivecyanosis

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    Vocal Nodules

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    VocalNodules o u esare nyswe ngson o e s.

    Excessivetalking,shouting,screaming,constant

    throatclearing,imitationofothersvoices

    noticedinchildrenandwomen

    preventtheVFsfrommeetinginthemidline&

    cause air leak throu h the vocal folds.

    Symptoms:

    rea yvo ce oarsevo ce

    tirednessontalkingforafewminutes

    noduleswilldisappearwhenvoicerest&voice

    therapy55

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    Polypsarebenignlesionsofthelarynx(mostlyin

    locatedontheoutermostsurfaceofthevocal

    Symptoms

    Breathyvoice&/Hoarsevoice

    Feelingoftirednessontalkingforafewminutes

    Voicetherapyaftersurgeryisnecessary.

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    Contactulcersarewearingawayofthemucous

    membraneovertheVFs

    causedbyvoiceabuse,pressedvoice,hyperacidity,.

    Symptoms:

    oarsevo ce

    Painwhileswallowing

    Painwhilephonation/speaking

    condition.57

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    Laryngitisisinflammation(tenderness,redness,&

    Duetoviralinfectionorvocalabuse/overuse.

    Symptoms:

    Change

    in

    voiceHoarsevoice

    Dependingonthecause,treatmentvaries.

    Voicerest,coughsuppressants,andsteam

    inhalationsrelievesymptoms.58

    Dysphonia Plica Ventricularis

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    DysphoniaPlica Ventricularis

    (VentricularDysphonia) WhenthefunctionsofthetrueVFsareaffected,

    ventr cu ar o s a se o s v rate

    Paralysisoftruevocalfolds,vocalabuse,andsevere

    laryngitiscauseventriculardysphonia.

    S m tomsHarshvoice

    Voicerestandvoicetherapycanrelievethesymptoms.

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    Causedbyinvoluntarymovementsofoneormore

    Causeisunknown,oftennoticedafterURTI,

    3majortypesofSD:

    1. Adductortype(spasmoftheVFscausesstrained,strangledandeffortfulvoice)

    2. Abductortype(laryngealspasmsresultsinsudden

    spurtsofwhispered/breathyvoice)

    3. Mixedtype(laryngealspasmscausessuddenstrained,

    strangulatedvoicealongwithspurtsofbreathiness) 60

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    Causedbytheabnormalrefluxofthestomachacid

    Mucosaofthepharynxandlarynxmaybedamaged

    Symptoms:

    Heartburn

    Swallowingdifficulties

    Regurgitationofstomachacid

    Hoarse/

    Harsh

    voice61

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    Cancer candevelopinanypartofthelarynx.

    3

    anatomic

    regions:

    the

    glottis,

    the

    supraglottis

    Mostlaryngealcancersoriginateintheglottis.

    Hoarsevoice&Sorethroat

    Swallowing

    difficulties

    LumpEarpain

    PersistentcoughwithStridor62

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    Surgicalremovalofthelarynxdue

    .

    typesTotallaryngectomy:completeremovalofthelarynx

    Hemi

    laryngectomy:

    partial

    removal

    of

    the

    larynx Alaryngectomee istaughttospeakusingeither,an

    artificial lar nx

    treachoesophegeal speechor

    esop agea speec .

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