I

IrondeficiencyanemiatestingAseasyasthrowinginthesponge!

@i@1It@1;iiH1@J@@ItI iIrosorb-59 is the second in a series of in vitro radio-pharmaceutical tests developed byAbbott Laboratories. The Irosorb-59 Sponge offers a remarkable degree of accuracyand simplicity that makes routine screening a practical mafter.

Accuracy : The diagnostic accuracy of the test is unsurpassed in measuring latent ironbinding capacity. What's more, unlike other methods, it can be used following the administration of a hematinic.

Speed: Irosorb-59 can be washed quickly, there being only 3 washes. No incubatorsor shakers are needed.

Convenience: Irosorb-59 is in a disposable kit form ready for immediate use at roomtemperature.

Safety : No dilution or pipetting of radioactive material is necessary. Since the patientreceives no radioactive materials, the test can be used in children, pregnant women,or in adults without any hazard of radioactivity.

Flexibility: The test does not require the presence of the patient for the determinationof the radioactivity. Serums can be frozen and saved until a sufficient number has beencollected to run a rack full of tubes at one time, or serum samples can be mailed to personnel performing the test.

Irosorb-59 is available to all doctors, hospitals and clinical laboratoriesAEC licensing is not required. 709418

IRDSDRB-'SB®DIAGNOSTIC KITABBOTT LABORATORIES NORTHCHICAGO,ILLINOIS

Abbott Laboratories, S.A., 2, rue Thalberg, 1201Geneva, Switzerland

I

ThyroidtestingAseasyasthrowinginthesponge!

@ _r1@ L@—@@

The Triosorb Sponge is an in vitro test providing accuracy, speed and convenience.

Accuracy: Because factors such as red blood cells and exogenous iodine have beeneliminated from consideration in the Triosorb Test, it is unsurpassed in accuracy.

Speed: With only 3 washes and no need for double pipettings, shakers, or incubators,the Triosorb Test can be more rapidly performed than any other T-3 test.

Convenience : Available in a disposable kit ready for immediate use at room temperature.There is no dilution or pipetting of radioactive materials with Triosorb. It is the simplestand most convenient thyroid function test to perform.

“Theresin sponge (Triosorb) technique is superior to the erythrocyte method for performing the [131T3 test in terms of simplicity, convenience and elimination of errorscharacteristic of the erythrocyte procedure.―

“TheT-3 uptake test was vastly improved by a resin-sponge. . . (Triosorb) . . . whichis offered as a replacement for the red cells as well as for the loose granular resin whichvaries from day to day.―2

Triosorb is available to all doctors, hospitals and clinical laboratoriesAEC licensing is not required.1. McAdams, G. B., and Reinfrank, R. F., J. Nuclear Med., 5:112, 1964.2. Manfredi, 0. L., et al., J. Nuclear Med., 7:72, 1966.

TRIDBDRB®—131TRIDBDR B—125

T-3 DIAGNOSTIC KITABBOTT LABORATORIES NORTHCHICAGO,ILLINOIS

Abbott Laboratories, S.A., 2, rue Thalberg, 1201Geneva, Switzerland

Announcing

TETRASD R B-125T-4 DIAGNOSTIC KIT

I

On the opposite page,Abbott announces its3rd “sorb―product

Tetrasorb -125.Please lift this page

for information aboutTriosorb®and Irosorb-59@

“Formany years the protein-bound iodine (PBI) has been used as an indirect index of the level ofthyroid hormones; however, in an appreciable number of cases it does not provide an accurate measurement, because compounds containing iodine or mercury are present.―

It is now generally recognized that a quantitative direct measurement of thyroid hormones in serumis the most valuable single laboratory aid in assessing thyroid function.

“Usinga resin-sponge and thyroxine tagged with 1-125, a simple method was developed to determineserum thyroxine.―2

That method is Tetrasorb-125, the first diagnostic kit offering a direct measurement of thyroid function by determining serum thyroxine. Hypothyroid patients show a decrease in serum thyroxine whilehyperthyroid patients show an increase.

Tetrasorb-125 is based on the principle of saturation analysis for measuring total serum thyroxine(T-4). Prior to the availability and convenience of the Tetrasorb-125 Kit, these results were reportedfor the T-4 test:

“WhenT4 and PB! values were compared, a good correlation (r=O.823) was obtained with a higherdiagnostic accuracy for the T4 determination. All euthyroid individuals with PBI's elevated due toiodine had T4 values in the normal range. . . . The T4 level correlated well with the clinical status inhypothyroid subjects receiving T4 or hyperthyroid subjects receiving various forms of therapy.―

“Unlikethe protein-bound iodine determination, this technique is entirely unaffected by iodine ormercury, an important advantage from the clinical point of view.―3

“Theseresults proved that this method could be used as a routine clinical diagnostic test in place of thedetermination of PB J@'4

By requesting both Tetrasorb-125 (a direct nieasure of thyroid activity) and Triosorb@ (an indirectmeasure of thyroid activity) for his patient, the physician is provided with more information than everbefore possible.

Tetrasorb-125 is available to all doctors, hospitals and clinical laboratories—AEC licensing is not required.1. Murphy, B. P. and Pattee, C. J., J. Clin. Endocr., 26:247, 1966.2. Kaplan, B. C., AAAS Meeting, Dec., 1966.3. Murphy, B. P., J. Lab. & Clin. Med., 66:161, 1965. 4. Nakajima, H., et. al., J. Clin. Endocr., 26:99. 1966.

Announcing TETRABDRB-125T-4 DIAGNOSTIC KITABBOTT LABORATORIES NORTHCHICAGO,ILLINOIS

Abbott Laboratories, S.A., 2, rue Thalberg, 1201Geneva, Switzerland TM—TRADEMARK.eio.@aR

I The Harshaw Chemical Company •Division of Kewanee Oil CompanyCrystal-Solid State Department________1945East97thStreet•Cleveland,Ohio44106•Phone216-721-8300HARSHAW

/Nal detectorsSi surface barrier dectorsBF3 & He3 gas filled detectorsElectronics

amplifierspreamplifiersvoltage suppliestime-logic circuitspulse shaping circuitscoincidence systems

PHA systemsamplifiers and preamplifiersvoltage suppliesscaler.timers

COINCIDENCEGAMMA-RAYSPECTROSCOPYWe put our NaI(TI) crystals together withour Ge(Li) detectors and let our Hamnerelectronics monitor the action. The actioncan be coincidence, anticoincidence orpair spectroscopy. And, we'll test the wholesystem for you before shipping.

Testing and giving you a copy of the datais possible because Harshaw supplies thethree major subsystems: Ge(Li) detector,NaI(Tl) crystal and Hamner electronics.. Our Ge(Li) detectors mount in the Sat.ellite cryostat making them portable (with3 days between refills). The detectors areavailable as planar-, thick planar-, true coaxial-, or five sided coaxial-type in active volumes to 45cc. Total system resolution from2.5 to 4.0 KeV (fwhm)for Co6°at 1.333MeV.

NUCLEARRADIATIONINSTRUMENTATION

complete,integratedHarshaw/Hamnersystemsorcomponentsfortoday'smostadvanceddisciplinesToday's physicists, working over a broad range of endeavors, will be interested inHarshaw's broad new capabilities. From crystals and solid state detectors to completedownstream electronics, you can select with confidence from the Harshaw line.

SPECTROS@X-RAYSPECTROSCOPYX.ray scintillation detectorsScintillation specialsElectronics

. The NaI(Tl) crystal shown above is 13½―diameter x 12―long. It has twQ opticallyisolated 6―sections, each with nine 3―photomultiplyer tubes. This crystal has a2½―well for the Ge(Li) detector. And wemake smaller crystals, too.. Hamner Electronics supplies the preamplifier, the amplifier, power supply,single channel analyzers, biased supply,a pulser for testing and many other combinations and modules. A new two widthtimer-scaler (NS.30) can be used in manycombinations. Of course, you can passthe information along to your multichannelanalyzer.

Harshaw offers you the system, anysingle component, or any combination ofcomponents.

HIGHENERGYPHYSICSRESEARCHCerenkov materialsOrganic scintillatorsInorganic scintillatorsHEP modular logic series (200 MHz). Discriminators

. Stretchers

Prescalers •Logic & Gate Interfaces•Fanouts •Logic & Trigger Units•Score Cards •Dual CoincidenceFast coincidence systems

NUCLEARLIFESCIENCEThermoluminescent Dosimetry

thermoluminescence detectorautomatic integrating picoammeterthermoluminescence analyzerdosimeters

CaF Scintillator Flow CellsNal with wellsSingle Channel Analyzers

ENVIRONMENTALSCIENCESScintillators

Ruggidized Scintillation DetectorsAerial Survey SystemGas Filled DetectorsElectronics

amplifiers and preamplifiersvoltage suppliesscaler-timerstime-logic systemscoincidence systems

Themostimportant

announcementfromAbbottRadio-Pharmaceuticals

sinceAbbott'sentryintothe nuclearfield.

@-----@@- @-@@@@@ --@

ISIAR1' STOP RESET

GAIN TNRESHOt@D WW400W

I

TM—TRADEMARK

AbboftLaboratoriesisnow

POWER PRESETCOUNT

Thisis theLOGICTMWellCounter

onlyincheslargerthanthispage(12w'x 41'16―x13―to be exact)

I

I

The LOGIC Series—themostis available now in 3 models.

compact counting systems ever designed

The LOGIC Counting Systems offer:•Compactness (micrologic integrated circuitry)* Dependability (pre-tested for 40 hours)

•Portability (25-35 lbs.)•Versatility (choice of 3 models)•Quality (backed by Abbott)

For tiiore ritolmation.contact your Abbott manwho knows both instrumentsand rad@o-pharmaceuticals

ABBOTT LABORATORIES NORTH CHICAGO, ILLINOISAbbottLaboratories,S.A.,2, rueThalberg,1201Geneva,Switzerland

inNuclearInstruments

a

: = — -@:-@--@ = = = = —@

@@@ @4@= ___: = =@ :i _@ = = — =— = ___ —@ -@-= = = @-_=:::=-:@ ==.. —= = —@ =—=@ @—:@@ @-:-::@@ =@==—I

- =@—@@ =

2@ —@ :@:::-: - •@“—-:@_:=-@= •-@@@ T @_@_ ==@— , : := .=.. @=. _;@;:. ==@ -:@:: :-:@::@ : .@ ;- -@@ = = _

I

1@ :@

I@ : = == @: @.@

:@

stercow 99@Technetium—99m

For high-definitiondiagnosticscansof brain lesions,thyroid,lungs,kidneys,liver,spleenand otherorgans.

High-definition scans are an essential in thefast- developing field of radio-diagnosis.Particularly so in the localisation of brainlesions and the scanning of thyroid, kidneys,liver, spleen and other human organs.Good scan resolution is one of the majorcontributions of the technetium-99m yieldedby Stercow 99m - an advanced-design sterile generator by Duphar.Supplies are despatched during the weekend pre-calibrated for the first day of use.usually Monday at 18.00 hrs MET. - and anelution efficiency of approximately 80% ofthe technetlum-99m in the Stercow is guaranteed. Further, milking is a simple, safeand speedy operation. Full details of Ster

cow 99m and the uses of the scanning agenttechnetium-99m will gladly be sent on request. Samples are available free of charge.Stercow 99m is manufactured by Dupharto the very high quality standards necessaryfor nuclear pharmaceuticals. A new designof sterile generator, it is available in threetypes with 150, 300 or 450 mc of the parentradioisotope Mo99. Complete elution with15,20 or 30 ml. When milked in the approvedmanner, the resultant technetium-99m issterile, non-pyrogenic and hence ready forimmediate use- either orally or intravenously.The Duphar Shielded Stercow Milking System gives additional safety and efficiencyin the elution operations.I

Contact our local representativeor write direct toN.y. Philips-DupharCyclotron and isotope laboratoriesPetten - Holland

Labelled Compounds C 14, H 3 - Enriched Compounds D, C 13, N 15, 0 18 - Nuclear Chemicals - Nuclear Products for Industry

Nuclearpharmaceuticals

I

1@

‘I

I

How?Withour newcomputer-compatibleMagnetic Tape System.

The two instrument consoles shown directly above constitute our MagneticTape System. In the console on the rightis our multidimensional analyzer. It connects to the Pho/Gamma Ill ScintillationCamera. This combination provides analog-to-digital conversion of data on thelocation and distribution of gamma-emitting radioisotopes in body organs.

The analyzer also encodes the data,in computer-compatible form. And thentransfers the data to the second console(left), the magnetic tape transport.

So much for theory. Application iswhere the Magnetic Tape System paysoff. Because the taped data on a multitude of clinical organ studies can now befed to a programmed off-line computer.

Which then does what a computer ismeant to do—analyze, correlate, andmanipulate data. To let you find out more,in more ways. New ways.

Of course you can play back the tape.And re-display and re-orient the data onthe analyzer's scope. Then photographthe scope display. Or read out the dataon a digital printer. Or—well,you're sureto find more to do with data In a convenient, permanent taped form.

But first you should talk to yourNuclear-Chicago sales engineer about

the Magnetic Tape System for Pho/Gamma Ill. And about our other new Pho/Gamma Ill accessories (fast digitalprinter, chart recorder, and 35-mm automatic time-lapse camera, among others).Or, if you'd like, write directly to us.

@1NUCLEAR-CHICAGOCORPORATIONA SUBSIDIARY OF G. o. SEARLE & co.

313 East Howard AvenueDes Ploines, Illinois 60018, U.S.A.

Donker Curtiusstraat 7, Amsterdam W.

Researchin the Serviceof Mankind

Now—thePho/Gamm@IIIScintillationCameratalkstocomputers.

Andlistens.i :—

-

P 0 IIII I

i‘I

I ‘I'‘I I'S S

I I'll

,,, I I P@I iii

I ‘III‘I I

II Ip I,

0

Six years of proven clinical effectiveness with Dual Head Scanners,has brought one fact to light . .don't plan the obsolescence of yourradioisotope scanner before youpurchase one.

The Model 54FD Dual Five is theonly scanner available that providesscallop-free photoscans. The 500cm/mm. maximum scan rate produces two opposed, simultaneousphotoscans before most other unitshave barely completed the first view.An exclusive miniscan system allowsa whole body scan to fit on a single14― x 17― film. A self-contained pa

tient couch affords the patient comfort, with no need for additionalmovement.

The Model 54 may be purchasedas a single head unit, and can beconverted to a Dual Head unit rightin your department.

Optional accessories include aninexpensive positron counting circuit and a two-isotope subtractioncircuit.

Write for the NEW Dual andSingle Head, Five and Eight InchRadioisotope Scanner Brochure. @‘I

@ l@

eee.De †;̃eee.@'T1 —•eeee'a

@eDa e@J1

III

11III.S

II j SJl@t. III II@

1 N@@I@

I,

‘ISI

‘1

II I, I'@If@

I UII I

I,@

1,1 SN II JNI@J ‘‘@I -I@

PP'S I'll I

UI LIJLI@

II

SI

II

JOUKNAL OF NUCLEAR MEDICINEx

There@snothingnewaboutDualHeadScanner8...Wavemadethemforsixyears.

@@III@

ohio-nuclear,Inc.1725 Fall Avenue, Cleveland, Ohio 44113 (216) 621-8142

;?@r@

corn lex I

SIL@ !

V

C*05155

VSQUIBB

I would like to receive full information on:

D Technetope@II (Squibb Technetium 99m)Sterile Generator

0 Tandem Milking with Technetope II

Please attach this coupon to your letterheadand mail to Medotopes Customer Service Dept.,P.O. Box #7, East Brunswick, N. J. 08816.

@@ Squibb Division of Nuclear Medicine

East Brunswick. New Jersey 08816

SQuIBBa research concept in nuclear medicine

IntroducingnewTechnetopéLISquibbTechnetium99mSTERILEGENERATORA FARSIMPLERGENERATOR...Hooks, hangers, and handles complicate assembly, soyouwon't find anyon TechnetopeII. It's sosimple that, after the usual aseptic techniques,assemblyconsists basically of two insertions intothe generator column. Then attach an eluent bottIe, an evacuatedcollecting vial, and milk. That'ssimplicity.

. . . DESIGNED WITH “T.D.S.― IN MIND

Time: Technetope II simplicity reducesassemblytime. ..keeping radiation exposureto a minimum.However, proper radiation safety precautionsshould be maintained at all times.Distance: Technetope II allows you to keep yourdistance.Youdon't haveto beconstantly nearthegenerator because it is self-milking. And eluatecollection is made at the side of the unit—awayfrom an unshielded port.Shielding: Technetope II has another half-valuelayerof leadshielding—withoutadding a cumbersome dispenser, additional cost, or special contract.

In addition, Technetope II is readily adaptableto tandem milking which provides high concentrations of 99mTcper mI.—anotherSquibb firstand exclusive.

Technetope II (Squibb Technetium 99m) Sterile Generator provides a means of obtaining asterile, non-pyrogenicsupply of Technetium 99m(99mTc).99mTc,the short-lived daughter (T'/2= 6hours) of Molybdenum99 (99Mo,T'/2=67 hours),is obtained from the generator by periodic elution.The amount (in millicuries) of 99mTcobtainedin the initial elution will depend on the originalpotency of the generator, while the activity obtamed from subsequent elutions will depend onthe time interval betweenelutions.

Warning: Proper radiation safety precautionsshould be maintained at all times. The columncontaining 99Moneed not be removed from thelead shield at any time. The radiation field surrounding an unshielded column is quite high.Solutions of 99mTcwithdrawn from the generatorshould always be adequately shielded. The earlyelutions from the generator are highly radioactive. For radiation protection, a lead shield forthe collecting vial is included with Technetope II.

For additional information on this advancedgenerator or the tandem milking technique,pleaseusethe coupon below.

I— — — — —— — — — — — — — — — —I

III

_______________________________________________III

_______________________________________________I______________________________________________ I

———————— ——————————————

ADDRESSCITY

STATE ZIP

I

EON Corporation, 175 Pearl St., Brooklyn, N.Y.

Gentlemen:Pleasesend me the reprints you offer as checkedbelow:

DA DB DC DD (pleasecheck)

NAME TITLE

INSTITUTIONEONCORPORATION•175 PEARL$TREETBROOKLYN. N.Y. 11201 •PHONE: 212488.0250

M

For your reference file―IN-VIVO RADIOISOTOPE uptakemeasurementsystems,and newdevelopmentsIn the useof radioisotopetechniquesfor rapid discriminationof hormonedependenttumors,areamongthe subjectscoveredin the reprintsdescribedbelow,availablefree for yourreferencefile fromEON Corporation.Indicateon the couponwhichreprintsyouwantandtheywillbe sent to you by return mail.

,@Generalcommentarycoveringavarietyofdevelopmentsin the use of radioisotope techniques, including a researchpaper “RapidDetection of Tumor Hormone Dependency byRadioisotope,―originally published in “TheSurgical Forum.―illustrated introduction.

D ThisreportwaspublishedbytheBiomedicalEngineeringDepartment of EON, in which both measurement systems andthe results of their use with a patient are discussed. The EONsystems predicted accurately which of two possible hormonetreatments for a cancer patient would be most effective.

--B Useofmicrominiaturizeddetectorsforifl-vivoradioisotopeuptake studies, experimental and clinical radiation dosimetry,are described in this report from the Biomedical EngineeringDepartment of EON Corporation.

I@Thisreprint,fromTheAmericanJournalofMedicalElectronics, describes the development of a variety ofinstrumentation for medical research and diagnosis, including“needle―probes for brain surgery, miniaturized thin-walleddetectors for localizing hemorrhage in the gastrointestinal tract,and miniaturized end window probes for ophthalmology,among others.

C)nl cne pre ar;@ter@stepHC1flOV'@ The LIa@

Nev@i Enqldnd Nuctear Corp

Simplicity?

.@ -

rACADEMIC @P

L -- -----@-- -

ESSENTIAL2ND EDITION, IN THREE

RADIATIONedited by FRANK H. ATTIX, U.S. Naval Research Laboratory, Washington, D.C. and W. C. ROESCH, Northwest Batelle, Richland, WashingtonThe second edition presents a unified review of therecent advances in the understanding of the fundamentals of dosimetry. It also discusses the new andimproved methods for the measurement of absorbeddose and other useful related quantities.Volume1FUNDAMENTALSI 1968,405pp.,$19.50Volume2INSTRUMENTATION/ 1967,462pp.,$20.00Volume3SOURCES,FIELDS,MEASUREMENTSANDAPPLICATIONS1969,about950pp.

RADIATION CHIMAERASby D. W. VAN BEKKUM and M. J. DE VRIES, Radiobiological Institute of the Organization for Health Research, T.N.O., the NetherlandsContains a complete review of the experimental workpublished on radiation chimaeras. It places emphasison the comparative aspects of bone marrow transplantation in irradiated animals and man and on thepathology of secondary disease. 1967,277pp.,$20.00

TRITIUM-LABLEDMOLECULES INBIOLOGY ANDMEDICINEby LUDWIG E. FEINENDEGEN, Director, Institute ofMedicine, Julich, GermanyA volume in the A.E.C.MonographSeries on Radiation Biology and Industrial Hygiene, prepared underthe direction of the American Institute of BiologicalSciences for the Division of Technical Information,United States Atomic EnergyCommission.Considers in detail the various factors affecting theuse of tritium-labeled compounds as tracers in biological and medical research. It provides an introduction to the physics of tritium and contains a reviewand evaluation of such major topics as the chemistryand production of tritiated compounds, counting techniques, autoradiography, and the toxicity of tritium inliving systems. 1967,430pp.,$17.00

DINGINSTRUMENTATION INNUCLEAR MEDICINEVolume1edited by GERALD J. HINE, International Atomic Energy Agency, Vienna, and Radioisotope Service, BostonDescribes comprehensively the fundamentals and recent developments of all important instruments usedin nuclear medicine. The theoretical as well as experimental aspects are presented together with specificinformation on applications. It also discusses recentlyperfected techniques such as radiochromatography,nuclear activation analysis, scintillating cameras andwhole-body counting, and explains various types ofradiation detectors such as semiconductors presentlyemployed in nuclear medicine. 1967,656pp.,$27.50

STRONTIUMMETABOLISMedited by J. M. A. LENIHAN, Western Regional HospitalBoard, Regional Physics Department, Glasgow, Scotland, J. F. LOUTIT, M.R.C., Radiobiological ResearchUnit, Harwell, England, and J. H. MARTIN, UnitedKingdom Atomic Energy Authority, Chapelcross,Annan, ScotlandProceedingsof the international Symposium on Some Aspectsof Strontium Metabolism held at chapelcross, Glasgow andStrontianA comprehensive and authoritative survey of currentresearch in strontium metabolism. Discussions rangewidely over issues related to the incorporation ofstrontium-90 in food chains, the uptake and excretionof strontium in man and- other animals, the relationships of strontium to calcium in bone, the modification of strontium metabolism by drugs or diet and thebiological hazards resulting from the presence ofstrontium-90 in the environment. 1967,354pp.,$14.50

INTERNATIONAL REVIEW OF

EXPERIMENTALPATHOLOGYVolume1edited by G. W. RICHTER, University of RochesterSchool of Medicine, Rochester, New York and M. A.EPSTEIN,Medical School,Universityof Bristol,Bristol,England December1968,about470pp.

VOLUMES

DOSIMETRY

For a Technical Bulletin giving fulldetails, write to

Centre Amersham England@•1@TheRadiochemicalTAS/RC.1S5/IA

Cyanocobalamin (‘7Co)BP is now offered inready-to-use capsules for routine diagnosisof pernicious anaemia.Capsulesof Hog intrinsic Factor Concentrateare also available if required.

The Radiochemical Centre supplies variouslabelled forms of vitamin B12,in a range ofspecific activities.

xviixxiv

Labelled'inconvenientcapsuleform

“In-Vitrodiagnostic testing should be a specialized area of interest―.We areconstantly striving to improve our products in our

@tpIwoa(•hloward execilenec

*T3 exchange column and l.S.G•1Aare the subjects of patents pending.

BlO .NUCLEdR LABORATORIES32325 South Coast Highway South Laguna, California 92677

WHAT'S@JI@NEW?r@mIheleadersinT3iesiiiig -

@ THE NEW HIGH SPEED i.S.G.1A*Using this new method, the I.S.O. T3 Syringes can produce from 3 to100 tests ready for counting in 30 minutes. The ideal method for the

busy hospital or laboratory. Any quantity (Up to 100 tests) .can becompleted in 30 minutes or less. How much time are you now spending? Requires 0.4 ml. of patient serum per test. No rotation or tern'peraturecontrolis needed.

T-3 EXCHANGE COLUMN*(Scholer, modified)

For those who prefer the t.b.i. or loose granular techniques. No finalpipetting and only 0.5 ml. patient serum is required. Inexpensive too!

1 2 3

I Magnascanner®500

2 Dual Magnascanner

3 Dynapix®

4 DynacameraTM

5 Magnacamera5

!!Whjchisthe betterchoiceforgamma imaging,

a scanneroracamera?―(Yes@

That'smuchlike: “whichis better:a planeor a car?―Surely it dependsuponthe problemat hand.

As it does with gamma imaging. Your one best betmight well be a scanner. Or a camera. You may needboth.Sadly,there can be no universalinstrument,noall-things-to-all-men system. Consequently, Pickernow offers five separate and distinct imaging devices:three are scanners,two are cameras.And this is themost complete line in the world. By far.

The implication is simple: the chancesare excellent that Pickerhasthe specificsystemthat preciselymatchesyour needs.Here now are some recognizable user requirementscoupledwith the appropriatePicker instruments.

Need:small hospital,startingstatic-imaging,smallpatient load,modestbudget.Or: largehospitalneeding additional diagnostic confirmation. Solution:Magnascanneresoo. Four out of five nuclear medicine departments start with a Magnascanner. Nowover 2000in usethroughoutthe world. Despitemanynew features and very high resolution, cost is modest.

Need:specializedstaticstudiesinvolvingtwoviewsat same time. Solution: Dual Magnascanner. Provides two large, high resolution scans simultaneously.

Need:heavystatic-imagingpatient load.Somedemandfor dynamicfunctionworkalso.Solution:Dynapix•.High speed static imaging with very high resolution. Also useful for medium speed dynamic functionstudies.

Need: broad capability for handling both staticimaging and dynamic function (and a great deal of it).Solution: Dynacamera'TM. Very fast instrument providing high resolution. Does both static and dynamicwork.

Need:sophisticateddynamicfunctionwork at veryhigh speeds. Solution: Magnacamera®.Exceptionally high speedfor studyingthe most rapid dynamicprocesses.

The conclusion: Picker has a wide selection ofimaging systems because there are many imagingneeds.Thewidestselectionin the world.Suggestion:describe your situation to your local Picker representative and ask him to develop solutions. Or, ifmore convenient, start by requesting our detailedgamma-imaging brochure. Write Picker Nuclear, 1275MamaroneckAvenue,WhitePlains,N.Y.10605.Dept.B

PICKER

from Lepeska Leasing) can beleased on a year-to-year basisat even lower monthly charges.Should you trade in your usedimaging system, lease paymentscan be reduced even further.

Obsolescence obsoleted.The plan I've been talkingabout so far is the standardone, which offers the lowestpossible monthly payments.But, if you, like many researchers and clinicians, view thefield of nuclear medicine as afast-moving one, then you'llwant to know about a specialplan of mine—the cancel-option plan. This plan includes acancellation option, to be exercised by the lessee, at the endof the 2nd (or 3rd or 4th) year.Although the lease paymentsfor such a plan will necessarilybe greater than those for thestandard plan, the advantageis one of flexibility. You cancancel when option time comesand re-lease new equipment.Or you can opt for continuationof the lease, with a subsequentreduction in payments.

Medicare and Blue Crosssay “yes―to these plans.

A second advantage to bothplans is that, by eliminatingthe purchase option, lease payments qualify as operating expense. And as such, they are100% chargeable to and reimbursable by Medicare, BlueCross, and ,imilar programswithout the need to estimateand justify a depreciationschedule. The cost of protecting your hospital from obsolescence can thus be properly andsimply shared.

4

I have formed an independentcompany—Lepeska Leasingthat will lease nuclear-imagingsystems under a unique type ofarrangement. The salient features of my plan are of such potential benefit to you that I'dlike to discuss them one by one.

“I'llbuy that.―(You don't have to.)

All currently available leaseplans for scanners, scintillationcameras, and the like are essentially conditional-purchase contracts. The lessee is given theoption to purchase the equipment at the end of the “leasing―period. In my standardplan, however, there is no purchase option in the leasingagreement. I offer you, quitesimply, the option to renewyour lease at the end of theagreed-upon period. I offer youa true leasing plan.

Costs vs. time.Here's the unique advantageto my standard lease plan.Since the lease payments arenot designed to make up theactual purchase price, the payments are therefore lower thanany other plan. You pay onlyfor usage of the imaging system. You lease from your operating budget, rather thanwaiting to buy the system fromyour capital budget. lo illustrate this important differencein payment, a brand-new imaging system with appropriateaccessories (nominally pricedat $40,000) can be leased fromLepeska Leasing for less than$800 per month over the standard lease period of five years.The same system would cost$1000 or more per month underother leasing plans with purchase options. And reconditioned systems (also available

I'mWillLepeska.I nowcanofferyoua totallydifferentleasingplanfornuclear-imagingsystems.

What kind of equipment?What kind do you want?

Lepeska Leasing, as an mdcpendent leasing company, permits you to choose equipmentof any manufacturer or to combine equipment from differentmanufacturers. You can choosefrom among the most respectednames in the field: BairdAtomic, Nuclear-Chicago, OhioNuclear, Picker Nuclear.

A word about me.In my recent capacity as marketing vice-president of Nuclear-Chicago Corporation, Igained much first-hand knowledge of the problems of startingand upgrading a nuclear-medicine facility. Now, I'm devotingmyself to the leasing of theimaging systems these facilitiesrequire. I know the field. Iknow the people in it. All ofthe independent activity of mycompany will be directed tosharing that knowledge withmy customers. Through a variety of low-cost, versatile leasingprograms and options.

Act.It comes down to this: If you'reconsidering buying or leasinga nuclear-imaging device or system, or, if your hospital is delaying the purchase of such asystem—contact me. In a meeting with you and your administrator, I can review theeconomics of leasing for yourhospital. Write to LepeskaLeasing, 109 South Cook St.,Barrington, Illinois, 60010. Orcall: (Area Code 312) 381-0775.

LepeskaLeasing

TBI-25, with iodine@125,is the T@3test of choice that you can usenow or a month from now. Stock ittoday. It's ready when you need it.

TBI-25 and TBI . . Your ChoiceTBI-25 with iodine-125 and TBI withiodine-131 are both available to

meet your individual T-3 require@ments. The TBI family, with directmeasurement of binding site up@take, offers a high degree ofaccuracy and takes less techniciantime. Write for full information andnew TBI booklet.

I

I

NOW!MallinckrodtI Nuclear

TBI-25...

NUCLEAR

UI

the1-3Testwithlongshelflife

SEE OUR OTHER N EW

PRODUCTS AT THE

RSNA MEETING

*1@

,..,,.

kit

(a@

RAD1OPHARMACEIJT1 CALSMALUNCKRODT CHEMICAL WORKS

Box 10172 •Lambert FieldSt. Louis, Missouri 63145

Atlanta •Chicago •ClevelandLos Angeles •New York •Montreal

Symposium:ImplantationTechnicsfor in-vivo in-situradioisotopeuptakestudies,experimentalandclinicalradiationdosimetry.Time:Tobe announced. Latefall, 1968.Place:To beannounced.Participation:Pleasewrite for invitation.Proceedings:If youcannotattend,pleasewriteandreserveyourcopynow.

Seeour full pagead on pagexiv

@jStjk@N.Y.ll2j@

TWO WEEK REFRESHERCOURSEFOUR TIMES YEARLY

Write for schedule, course outline and application

REFRESHERCOURSEIN NUCLEARMEDICAL TECHNOLOGY,INC.

An Independent, Not-for-Profit Organization

Ask for subscription information to “THENUCLEAR

MEDICAL TECHNOLOGIST'S FORUM.―A bi

monthly instructive letter for progressive technolo

gists. $3 per year 8 issues.

POST OFFICE BOX 1033

La Grange Park, Illinois 60525

Phone: 312-352-6597

INDEX TO ADVERTISERS

Abbott LaboratoriesNorth Chicago, Ill Cover, i, v, vi, vii,

xxvi, xxvii

Academic PressNew York, N.Y xvi

Baird-AtomicCambridge, Mass xxviii, IBC

Bio-Nuclear LaboratoriesSouth Laguna, Calif xix

Duphar Nuclear Corp.Amsterdam, Holland viii

Eon CorporationBrooklyn, N.Y xiv, xxiv

Harshaw Chemical Co.Cleveland, Ohio ii

Lepeska LeasingChicago, Ill xxi

Mallenckrodt/NuclearSt. Louis, Mo xxii, xxiii

New England Nuclear Corp.Boston, Mass xv, xxv

Nuclear—ChicagoCorp.Des Plaines, Ill ix, BC

Nuclear Medical Technology, Inc.La Grange Park, Ill xxiv

Ohio—NuclearCleveland, Ohio x

Picker NuclearWhite Plains, N.Y xx

Radiochemical CentreAmersham, England xvii

Squibb, E. R. & SonsNew York, N.Y xi, xii, xiii

xxiv JOURNAL OF NUCLEAR MEDICINE

NEN Pharmaceutical Division575 Albany Street, Boston. Mass. 02118Telephone (617) 426.7311 Telex 094-6582

CHARCOATT-3. No fuss,no muss, no rnu1tip@epipetting

or rinsing.

I*

a

L POSTERIOR R LEFT LATERAL

For brain scanning, Pertscan-99m providesmore information with less radiation to thepatient than any other related cerebral testwhether other radiolsotopes or x-rays. And youget each projection fast—aslittle as 2 minuteswith a camera, 15 minutes or less with rectilinear scanners.@

A 54-year@o1dman was hospitalizedwith progressive weaknessof the right side, followed byseizuresof the right side (Jacksonianseizures).Brain scans showed an abnormal concentrationof isotope in the left parasagittal area. Surgeryrevealed a meningioma, which was removed,and the patient recovered.

The 2 scans above, showing the marked abnormal uptake (which turned out to be a menigioma), were made with Pertscan-99m. Thisproduct isshipped Monday through Friday—andSunday. Thus, brain scans can be scheduled 6daysa week—MondaythroughSaturday.

INDICATIONS:Adjunctive diagnostic aid in detectingand localizing intracranial neoplastic (primary ormetastatic) and non-neoplastic lesions.

CONTRAINDICATIONS:Radio-pharmaceutical agentsshould not be administered to pregnantwomenor topersons less than 18 years old unless the indicationsare very exceptional.

PRECAUTIONS:Care should be taken to ensure minimum radiation exposure to the patient as well as allpersonnel; to prevent extracranial contamination because this can lead to erroneous interpretation; andto differentiate areasof abnormal activity from areasof normal vascular activity.

Pertscan-99mSODIUMPERTECHNETATEIc 99mAlso available:

Pertgen-99mTECHNETIUM99mGENERATORKIT

AbbottLaboratories,S.A.,2, rueThalberg,1201Geneva,Switzerland8@464@

Insuspectedbrainpathology,findoutfastwithPertscan-99m

ABBOTT LABORATORIES NORTH CHICAGO, ILLINOIS

TM—Trademark

Sb, ...

Sb • .4

4 4

*

aa.9

a .@-@a@@ —@@ ..‘@ @*-@ -

m@ *

@.. 0

0eta • *

@)*

51

_1p,55 ,p

C@.*

— 1.

I-J@.

@ *

p.4

per.

a

1* m@ a,?I, • •@

— _R**, 4

*- * 4.-i@ .@

@ .51 .51

pe@4. -4 -

mia resulting from compressionor obstruction'of pulmonary arteries. .Surgery and/or other therapy for lung disorders: To evaluate the effectiveness of therápeutic measures.Macroscan-131 is sterile and non-pyrogenic.It is ready to use and should not be heatedprior to use.INDICATIONS:For scintillation scanning of the lungs toevaluate total, unilateral, and regional arterial perfusionto the lungs.cONTRAINDICATION:Radio-pharmaceutioal agents shouldnot be administered to pregnant women, nursing mothers, or to persons less than 18 years old unless the indications are very exceptional. -PRECAUTIONS,SIDE EFFECTS:Care should be taken toadminister the minimum dose consistent with safety andvalidity of data. The possibility of an immunological response to albumin should be kept in mind when serialscans are performed. There is a theoretical hazard inacute cor pulmonale, because of the temporary smalladditional mechanical impediment to pulmonary bloodflow. A possible case of urticara has beenrelated to a similar preparation. The thyroidgland should be protected by prophylactic administration of concentrated iodide solution.

TM—TRADEMARK 709400

AbbottannouncesMacroscari-131At@REGAT[DRADIO-IODINATED(1131)ALBUMIN(HUMAN)

If it's a pulmonaryproblem,Macroscan-131picturesit!Pulmonary embolism, suspected: To confirm(or rule out) its occurrence.

Chronic pulmonary tuberculosis: To estimateunilateral and regional function and perfusionof the lungs.

Emphysema: To evaluate the degree of focallack of perfusion.Pneumonitis: To evaluate the decreased regional blood flow that occurs without obstruction of vessels.Lung tumors: To evaluate the regional ische

I,.

J

!. -

I

‘@@

I —iaatIa. ‘I____a

aa a

TheBaird-AtomicAutofljoroscope®cando thingsthat no other scintillationcameracan.

Fact:TheBaird-AtomicScintillationCamerais theonlyCamerathat can providequantitationof patientdatawith realnumbersas readdirectly from thefront panel.Youcan do cardiovasculardynamibsandcerebralbloodflow dynamicsbothvisually and quantitatively. And you can do lung, pancreas, thyroid, placenta, andother static analyses.The Autofluoroscopeis the only systemthat can providepermanent patient recordstoragewith instant recalI of all the originaldata in unalteredform.Up to threeareasof quantitationcan beoutlinedbya light penandpresentedto the multiple pen recorderfor a graphicdisplayof total organactivity versustime. It is the onlycomplete instrument havingall the high demandcomputerfunctions built into the system. Let us proveto you that the Baird-AtomicScintillationCamerawill do everythingwesay it will. 33 UniversityRoad, DAIRDA1OMIOCambridge,Mass.02138, Telephone617 864-7420•Baird- ‘@-Atomic Europe,TheHague,The Netherlands.Baird-AtomicLtd., Hornchurch,England.

--- .— . Wit,' maricea tfl1•O@t S)'tTl@tbITl8.

scintiu@ionCamera(sIn'tI-lA'sht@nkArn'érA).The Pho/Gamma@It) Iflanufactur@j byNu(lear Chicago(Torpora@jOfl Pro

V1(j@@ Visual

@/.Htio@ and record

ng of radioisotope(iL@ttrIb@jtjon jfl body

Organs through aVariety of readoutte('hfliques.

Scintidigit (sln'tI-dlj'lt) .Digitized record, on papertape of total number of@‘ountsaccwnula@-j during@

each Pho/Ga@nia Ill ex-@amining period. Produced@ __________hy high.spee@ digital @/printer acc@o,@y

SCifltjphoto (sin't1-fö't@). Photographic recordingof radiobo@p@ distribution in body organs, as

played on Pho/Gamma III asciiloscope. Scintiphotos can beeither 1. individuai, self-develop

Sc1ntq@hotn@@ ing pictures

exposed duringtotal examination period and processed by triplelen.s(amera supplied with Pho/Gamina ILL or 2.serial, time-lap@ pictures made throughout examnation period on 35mm film by optional automatic

tune@-lap@(amera available for Pho/Gamma III.scintiplot (sin'ti-pl@t'). Analog record, on chart

paper, of radio@@ isotopedistribu_________ tion, as visualized

__________ @.-T@zi by Pho/Gam.ma

III. Used espe(tally for renal studies, when Pho/Gamma III

detector LSoperated in divided-crystal mode. Pro(lured by dual-channel ratemeter/dual-pen re(order a(c-esso@-y combination.

Scintitape (sin'ti-tãp') .Magnetic-tape recording of“ho/GammaIII data. Produced hy magnetic tapesystem accessory Clinical information is transferred to tape bysystems multidimensional analyzer. Tape is manipulated by qsystem's tape transport. Taped(lata can be 1. played back for•l)hotographic recordtng from analyzersscope as digital scintiphot@ (DSP). or 2.fed to an off-line computer for automaticJ)roces@-ng and analysis.

We'rehelpingaddsomenewwordsto the“diagnostic

@ dictionary.―

t'SUtflt.@ :t

“dr.@.f'@,It-I,-

s; Cr. SIJf)/J@@a@@ IIt@'j@'.

htr ‘@)I1(.(@f I

A h.(. @)tI( 1.UStrag@)lus@lI1d

flflh@iti@n of theOCllØfldr()sjs of

L.1.Th@sho,.1@.in the back of

@1

Dsterjor VIP-a': 1,fosaa; 2, infra

, 3. SUp(r,or mar

)Ular (corao.@id@liar), margin; 5,r; 7, iflforinr)f th@4scap@@@;9,gin; 10. Spin.; ii,

,h@tendon øfthe.lade mnvr.,@; 12,artorjal forarnr.n;

‘rocus@(Leidy).

r. ektom@CXcje scapula or a

-te're-or) . Deiransvers,,@ prc@cIanteriorlyklah-vik'u@inr @.clavicle.

@[scapula + Gr.the shoulder.er-al). Pertain.Is.scapula + Cr.:ing the scapubmyopathy.14.e're-or). De

II

U

Because we've dome up withsomeexcitir@gnew @ccessoriesfor the Pho/Gamma®IllScintillation Oa.me@a.

Perhaps nc$! all erthe..words in our “dictionary―will end upi.irf the clinician'svocabulary. Frankly, we invented most ofthem. For a reaso@ To help illustrate thenewly expanded versati@ty of Pho/GammaIll for the processing, storage, and analysis of data on radioisotope distribution inbody organs and areas.

And versatility is the key word. NowPho/Gamma Ill can help you learn more,in more ways, than ever before.

For example: To the familiar scintiphoto must now be added sequentialscintiphotos. They're taken with our new35-mm automatic time-lapse camera. Itfits right on one of the twin scopes on thePho/Gamma III console.

Other new additions include analogchart records, digital p;intouts, magnetictape—all new, all briefly defined in ourdictionary.

Why not use it as a point of departurefor a talk with your Nuclear-Chicago sales

engineer. Or write to us for all of thewords on Pho/Gamma III and Its expanded array of accessories.

Research in the Service of Mankind

NUCLEAR-CHICAGOCORPORATIONA SUBSIDIARY OF 3. o. SEARLE & CO.

313 EastHowaraAvenueDes Plaines, Illinois 60018, U.S.A.

Donker Curtiusstraat 7, Amsterdam W.