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8/2/2019 Endocrinology TEXT

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Note that 1,25 (OH)D has a SIGNIFICANT effect on Ca levels

if there is failure to absorb vitamin D from GI tract, it leads to decreased kidney 1,25 OH and

significant loss of calcium plasma, DESPITE INCREASED PTH (due to low Ca levels)

- This is because your are MISSING the absorptions of Ca from BOTH kidney and GI tract

Note: if there is increased PTH wouldn't that lead to more bone resporption as well?

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