Donohue Timothy 11100338 Glaucoma Presentation

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    Glaucoma

    Timmy Donohue

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    History of the Disease

    The disease has been known for centuries dating back to

    the ancient Greek civilization

    The Greek philosopher Hippocrates describe how

    blindness often occurred in more elderly people, whichhe called glaucosis

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    History of the Disease

    Despite its discover many centuries prior, scientists were

    only able to understand and identify the disease in 1851

    through the invention of the Ophthalmoscope by

    Hermann Von Helmholtz

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    What is Glaucoma?

    Glaucoma is the term used to describe a network of

    vision related disease that result from damage to the

    optic nerve that causes vision loss and even blindness

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    What is Glaucoma

    Two of the most common types of glaucoma include:

    Primary Open Angle Glaucoma and Primary Angle

    Closure Glaucoma

    Despite their different names, they are almost identicalin their causes and symptoms

    Primary Open Angle Glaucoma Primary Angle Closure Glaucoma

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    Causes of Glaucoma

    Glaucoma is often attributed to an increase in the

    intraocular pressure in the eyes

    The normal IOP for humans is 14-16 mmHg

    Whereas, in people with glaucoma, the average is at 22mmHg

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    Causes of Glaucoma

    This buildup of pressure can be the result of many

    environmental stresses including: sleep apnea, darkness andemotional stress

    However, the development of the disease is more commonly

    attributed to old age and the inability of certain parts of theeye to function

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    Causes of Glaucoma

    Contemporary research has

    shown that there might be a

    genetic defect that can cause

    glaucoma

    In patients with primary

    open angle glaucoma,

    changes in the DNA

    sequence at genes includingCaveolin 1 and 2, as well as

    deletions in DNA at genes

    including TBK1

    Alteration of the serine protein was found to cause glaucoma

    in mice

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    Causes of Glaucoma

    Despite their discovery of the genetic

    mutations found in many different types of

    glaucoma, scientists are still attempting to

    discover their significance

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    Symptoms of Glaucoma

    In Open angle glaucoma, there are no

    noticeable symptoms until severe vision loss

    after the pressure in the eye has accumulated

    over time

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    Symptoms of Glaucoma

    In closed angle glaucoma, the most common

    symptoms include: hazy or blurred vision,

    severe eye and head pain, nausea or vomiting,

    and sight loss

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    Symptoms of Glaucoma

    As glaucoma can result in vision loss, it is very hard for

    the person with the disease to perform daily activities, as

    they cannot see very well, if at all

    Also, this disease may be very hard on the patients familyas they have to care for them, as they have a hard time

    seeing things

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    Identification of the Disease

    In closed angle glaucoma, the disease is nearly

    impossible to notice, as the effects of the disease dont

    kick in until many years after the disease is contracted

    However, if one were to visit an eye doctor, the doctorwould be able to notice that they have glaucoma

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    Identification of the Disease

    In all other types of glaucoma, the disease is easily

    identified, as the symptoms are visible very early in the

    development of the disease

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    Identification of the Disease

    Scientists have also found that certain types Glaucoma

    are hereditary

    If a persons parents were to have had glaucoma, that

    person would be 9 times more likely to contract thedisease

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    Treatments for Glaucoma

    Common treatments for glaucoma include eye drops,

    pills, and laser surgery

    These treatments are all more effective early on in the

    diseases development as vision loss is irreversible

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    Bioethical Considerations

    One of the main ethical concerns regarding Glaucoma

    lies in the question: to treat or not to treat?

    As there is incomplete knowledge regarding the

    diagnosis and management of the disease in patients,many of them receive the incorrect treatment, which can

    cause great harm to their vision

    Therefore, scientists are attempting to get a better

    understanding to try and avoid these confusions

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    The EndWorks Cited

    Fazio, Doreen. "What Are the Symptoms of Glaucoma?" Glaucoma Research Foundation. N.p., 24Apr. 2012. Web. 28 Feb. 2013.

    The Glaucoma Foundation. "PRIMARY OPEN-ANGLE GLAUCOMA (POAG)." Primary Open-Angle

    Glaucoma (POAG). The Glaucoma Foundation, 2013. Web. 28 Feb. 2013.

    The Glaucoma Foundation. "TREATING GLAUCOMA." How Glaucoma Is Treated. The Glaucoma

    Foundation, 2013. Web. 28 Feb. 2013.

    Simon, Harvey. "Related Content." Glaucoma. University of Maryland, 23 June 2009. Web. 28 Feb.

    2013. Unknown. "Result Filters." National Center for Biotechnology Information. U.S. National Libraryof Medicine, n.d. Web. 28 Feb. 2013.