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B.PHARM. SEMESTER-I

101(A) T: REMEDIAL MATHEMATICS

Objective:

To perform mathematical operations with confidence, speed and accuracy.

To think and reason precisely, logically and critically in any given situation.

To conceptualize, inquire, reason and communicate mathematically, and to use mathematics

to formulate and solve problems;

To develop the abilities and skills that lead to discovery and inventions.

S. No.

Topic No. of Classes

1. Algebra: Equation reducible to quadratics, simultaneous equations (linear and

quadratic), determinants, solution of simultaneous equations by Cramer’s rule,

matrices, definition of special kinds of matrices, arithmetic operations on

matrices, inverse of a matrix, solution of simultaneous equations by matrices,

pharmaceutical applications of determinants and matrices, evaluation on En1,

En2 and En3, menstruation and its pharmaceutical applications, measures of

central value, objectives and pre-requisites of an ideal measure, mean, mode

and median.

15

2. Trigonometry: Measurement of angle, t-ratios, addition, subtraction and

transformation formulae, t-ratios of multiple, submultiples, allied and certain

angles, application of logarithms in pharmaceutical computations.

07

3. Analytical plane geometry: Cartesian co-ordinates, distance between two points, area of triangle, a locus of point, slope and intercept form of straight line, double-intercept form, normal (perpendicular form), slope-point and two point form, general equation of first degree.

08

4. Differential calculus: Limits and functions, definition of differential

coefficient, differentiation of standard functions including function of a

function (chain rule), differentiation of implicit functions, logarithmic

differentiation, parametric differentiation, successive differentiation.

07

5. Integral calculus: Integration as inverse of differentiation, indefinite integrals

of standard forms, integration by parts, substitution and partial fractions,

formal evaluation of definite integrals.

06

Total No. of Classes 43

101(B) T: REMEDIAL BIOLOGY

Objective:

To understand the processes and patterns of biological evolution, and the role of evolution

as the central unifying concept in biology and learn the basic structure and function of

cells as the basic units of all living things and as the building blocks of multicellular

organisms.

To understand the historical and social context of biological thought and research, and the

contributions of biology to the resolution of ethical, social, and environmental issues in

human affairs.

S.No. Topics No. of Classes

1 Simple and compound microscopes used in biology. 2

2 Plant anatomy and physiology: Structure of plant cell, mitosis and meiosis, classification of plants, different types of plant tissues and their functions, transportation,

4

3 Morphology and histology of root, stem, bark, wood, leaf, fruit and seed, modifications of root and stem.

5

4 Study of the following families with special reference to medicinally important plants - Apocynaceae, Solanaceae, Rutaceae, Umbelliferae, Leguminosae, Rubiaceae, Liliaceae, Graminae, Labiatae, Cruciferae and Papaveraceae.

10

5 General survey of animal kingdom: Classification of animal kingdom, structure and life history of parasites like amoeba, entamoeba, trypanosoma, plasmodium, taenia, ascaris, schistosoma, oxyris and ancylostoma

10

6 General structure and life history of insects like mosquito, housefly, cockroach, mites and silkworm

8

7 Photosynthesis and respiration in plants, plant growth and development.

3


102 T: COMPUTER APPLICATIONS

Objective: To understand the basic parts of computer, Computer fundamentals, Programming, Office Tools and Network.

S. No.

Topic No. of Classes

1. Introduction to computer: Definition, characteristics, generation of computers, capabilities and limitations, introduction to operating system, concept of bios, booting files, basic components of a computer system-control unit, ALU, input/output functions and characteristics, memory introduction, classification-volatile memory and non volatile flash memory, ROM, RAM, EPROM, PROM, EEROM other types of memory.

05

2. Input, output and storage units: Computer key board pointing devices: mouse, trackball, touch panel and joystick, light pen, scanners, various types of monitors, touch sensitive screens, optical recognition system, pen based systems, digitizers, MICR, OCR, OMR, bar-code reader, digital camera.

03

3. High level language and low level language, software and its different types, system software, application software, hardware, firmware, compiler, interpreter and assembler, file allocation table (FAT, FAT32 & NTFS), introduction to algorithm and flow chart, representation of an algorithm, flowchart symbols and levels of flow chart, rules, advantage and limitation of flow chart and pseudo code.

07

4. Computer fundamentals and programming: Data types, variables, constants, operators, (including bitewise operations), expressions, assignment, statement, arrays, function, pointers, structures union and enumerated data type, binary search.

07

5. Office tools: Word, excel softwares, MS-power point Word: Structure of document, common commands, styles, cross-reference.

Excel: Concept of spreadsheet, use of financial and statistical functions, sorting and searching database, linking workbooks, formula between work books. Power Point: Creating, formatting and addition of special effects to a presentation, viewing a presentation and managing slide shows.

10

6 Computer network: Introduction, types of computer network, LAN, MAN, WAN, OSI reference model. Communication media: Types of communication media, guided and unguided internet application.

06

7 Computer applications in Pharmacy and clinical studies. 02


103 T: PHARMACEUTICS-I (INTRODUCTION TO PHARMACEUTICS)

Objective:

To provide an introduction to the profession of pharmacy including its history, scope,

dosage forms, official standards and official preparations.

S.No. Topic No. of Classes

1. History of pharmaceutical practice through ages, pharmacy as a

career.

04

2. Pharmacopoeias with special reference to Indian, British, United

States, International and Extra Pharmacopoeias and various systems

of medicines.

06

3. Routes of administration and classification of pharmaceutical dosage

forms.

05

4. Definition, general formulation, manufacturing procedures and

official products of following categories: Aromatic waters, solutions,

syrups, spirits, elixirs, linctuses, lotions, liniments, glycerites, gargles,

mouth washes, inhalations, milk and magmas, mucilages, jellies,

infusion, decoctions, tinctures and extracts.

16

5. Methods employed in the preparation of plant extracts. 04

6. Coarse dispersion: Suspension, interfacial properties of suspended

particles, theory of sedimentation, effect of Brownian movement,

sedimentation of flocculated particles, sedimentation parameters,

formulation of suspensions, wetting of particles, controlled

flocculation, flocculation in structured vehicles, rheologic

considerations, methods of preparation, physical stability of

suspensions.

06

7. Emulsions: Types of emulsion, theories of emulsification

(monomolecular adsorption, multi-molecular adsorption and film

formation and solid-particle adsorption), physical stability of

emulsions, creaming and Stoke’s law, coalescence and breaking,

phase inversion, evaluation of emulsion and pharmaceutical

applications.

05


104 T: PHARMACEUTICAL CHEMISTRY-I (ORGANIC-I)

Objective: To understand the basic principles regarding structure and reactivity of organic molecules. Emphasis is on the substitution and elimination and chemistry of different types of groups.

S.No. Unit/Topics Teaching Hours Required

01 Fundamentals of organic reaction mechanism: Classification of organic reactions, bondbreaking and bond-making processes, concerted and stepwise reactions, reactivity and orientation, electrophiles and nucleophiles, aromatic, role of solvent, polarity of solvent.

05

02 Reaction intermediates: Transition states, rearrangement, carbanions, carbocations, carbon radicals, carbenes, nitriles and benzyne.

06

03 Stereochemistry: Stereoisomerism, enantiomers, elements of symmetry, chirality, racemic modification, configuration, specification of configuration, sequence rule, conformational isomers, reactions involving stereoisomer’s, asymmetric synthesis.

07

04 Study of reaction mechanism:

Addition reactions:

(a) Nucleophilic addition reactions: Nucleophilic addition to C=O, addition of cyanides, derivatives of ammonia, alcohols, Grignard’s reagent, Aldol condensation, nucleophilic

addition to C=C

(b) Electrophilic addition reactions: Addition of hydrogen, halogen, hydrogen halide, sulphuric acid, water, halohydrin formation, dimerisation, alkanes, oxymercurationdemercuration,

hydroboration-oxidation, stereoselective and stereospecific reactions, comparison of nucleophilic and electrophilic addition in alpha-beta unsaturated carbonyl compounds.

(c) Free radical addition reactions: Peroxide initiated addition of HBr (anti-markonikov orientation)

Elimination reactions:1,2 Elimination reactions, dehydrohalogenationof alkyl halides, E1, E2, E1cb, E1 vs E2, elimination vs substitution.

Substitution reactions:

(a) Free radical substitution: Halogenation of alkanes

18

(b)Nucleophilic Aliphatic: SN1, SN2, SN1 vs SN2, neighboring group effect

(c)Nucleophilic Acyl substitution: Esterification reactions, conversion to acids, acid

chlorides, amides, esters, nucleophilic substitution alkyl vs acyl.

(d)Electrophilic aromatic substitution: Nitration, sulphonation, halogenation, Friedal

Craft’s alkylation, electrophilic substitution in naphthalene.

(e)Nucleophilic aromatic substitution: Bimolecular displacement, benzyne, and aliphatic vs aromatic substitution

05 Condensation and rearrangement reactions: Claisen condensation, Reimer Tieman reaction, Hoffmans degradation of amides, Kolbe’s reaction, Fries rearrangement, Cannizaro’s reaction and coupling reaction.

06

105 T: PHARMACEUTICAL CHEMISTRY-II (INORGANIC)

Objective:

Inorganic chemicals have been used in pharmacy and medicine for many reasons ranging

from therapeutic to nutritional supplements to pharmaceutical necessities. The course is

designed to study the principles of inorganic chemistry to pharmaceuticals and to study those

inorganic agents used as pharmaceutical aids and necessities or as therapeutic and diagnostic

agents.

(A) Discuss the importance of impurities in pharmaceutical materials.

(B) Learning method of manufacturing, physical/chemical properties, storage and uses of

important inorganic substances used for pharmaceutical purpose.

(C) Learning biological role of inorganic ions and its possible involvement in various

diseases.

(D) Learning basic analytical methods for pharmaceutical inorganic substances.

(E) Study various aspects of radioactivity, its diagnostics as well as therapeutic usefulness

and harmful effects in environment.


01 The occurrence of impurities in pharmaceutical preparations: Types of impurities and limit test for chlorides, sulphate, arsenate,

07

lead, heavy metals and iron.

02 Group IA: Sodium and potassium compounds: Sodium benzoate, sodium bicarbonate, sodium borate, sodium chloride, sodium citrate, sodium fluoride, sodium metabisulphate, sodium phosphate, sodium potassium tartarate, potassium permanganate, potassium dichromate, potassium chloride, potassium bromide and potassium iodide.

Group-IB: Copper, silver and gold compounds: Copper sulphate, silver nitrate, strong silver proteins, and mild silver proteins.

Group-IIA: Magnesium, calcium and barium compounds: Light and heavy magnesium carbonate, light and heavy magnesium oxide, magnesium hydroxide, magnesium sulphate,

magnesium trisilicate, magnesium strearate, calcium gluconate, calcium acetate, calcium carbonate, calcium chloride, calcium lactate, and barium sulphate.

Group IIB: Zinc and mercury compounds: Zinc oxide, zinc sulphate, zinc stearate, zinc chloride, mercury, yellow mercuric oxide, mercurous chloride and ammoniated mercury.

10

03 Group IIIA and IIIB: Boron and aluminium compounds: Boric acid, aluminium hydroxide gel, aluminium magnesium trisilicate and alum.

Group IVA and IVB: Bentonite, light and heavy kaolins and kaolin poultice.

Group VA and VB: Nitrogen, antimony, and bismuth compounds: Strong and diluted ammonia solutions, strong ammonium acetate solutions, ammonium chloride, sodium antimony gluconate and bismuth subcarbonate.

10

04 Group VIB: Sulphur, selenium compounds: Sublimated sulphur, precipitated sulphur and selenium sulphide.

Group VIIA and VIIB: Hydrogen, oxygen and halogen compounds: Purified water, water for injection, hydrogen peroxide, chlorinated lime, aqueous iodine solution and strong iodine solution.

Group VIII: Iron compounds: Ferrous sulphate, ferrous gluconate, ferric ammonium citrate, and iron-dextran inj.

05

05 A study of major intra and extra cellular electrolytes, essential and trace elements and their physiological role.

04

06 Selected case studies in medicinal inorganic chemistry from the 04

106 P: COMMUNICATION SKILLS & PERSONALITY DEVELOPMENT-I

Objectives:

Developing grammar, vocabulary and mechanics for communicative English.

Developing English reading skills and comprehending.

Understanding of body language and its usage.


1. Orientation class 1

2. The most commonly used grammatical items in technical English 1

3. Word usage, related forms, foreign roots, prefixes and suffixes 1

4. Technical communication and conversational expressions, 1

5. Misused and misspelled words, transitional words and phrases, 1

6. Antonyms and synonyms, 2

7. Mechanics and punctuation: 2

8. Common grammatical and stylistic errors 2

9. Parallelism, embedding sentences within sentences, wordiness,

inappropriate jargon

1

10. Reading comprehension: 1

11. Rewriting a ‘receptive passage’ as a ‘skim passage’, scanning a

passage for specific information,

2

12. Functional English, starting a conversation, responding

appropriately

2

13. Right body language 2

14. Concluding class 1


following topics:

a. Biomedical uses of lithium

b. Application of platinum compounds in medicine

c. Gold (I) compounds as therapeutic agents

d. Ruthenium, titanium and gallium compounds in medicine

07 Metal compounds as contrast agents for MRI and medicinal applications of radio-active compounds.

02


B. PHARM. SEMESTER-III

301T: PHARMACEUTICS-III (PHARMACEUTICAL ENGINEERING) Objectives:

Design and development of pharmaceutical equipments, Safe handling and use of Pharma

machineries.

Design of efficient process for pharmaceutical material handling and manufacturing

process.


1. Orientation class 1 2. Induction class-Introduction to the subject 1 3. Introduction to unit operations-illustration of significance of unit

operation, terms used in unit operations. 1

4. Objectives, applications and theory of size reduction 2 5. Mechanism of size reduction and classification of mills. 1 6. Industrial mills for size reduction 1 7. Theory of size separation 2 8. Techniques of size separation 1 9. Theory of drying 1 10. Industrial Dryers-construction working application etc. 2 11. Special drying techniques 1 12. Principles of evaporation 1 13. Evaporating pan and others. 1 14. Film evaporators and condensers 1 15. Distillation Principles 1 16. Different distillation techniques 2 17. Theory of mixing liquid- liquid, solid-solid. 1 18. Industrial mixers 1 19. Solid liquid mixing theory and equipment. 1 20. Theory of filtration 1 21. Industrial filters-mechanism, working and applications etc. 2 22. Theory of centrifugation 1 23. General Classification, Various lab centrifuge, industrial

centrifuge 1

24. Material of plant constructions-Introduction, classifications, factors affecting selection etc.

1

25. Significance and use of Plastic, glass and S.S. 2 26. Theory of crystallization 1 27. Crystallization techniques 1 28. Industrial crystallizers 2 29. Refrigeration and A.C. application Humidification and

dehumidification process and terms, importance of control 1

30. Measurement of humidity 2 31. Humidifier and dehumidifiers 1 32. Corrosion –Types and prevention 1


302 T: PHARMACEUTICS IV (DISPENSING, COMMUNITY AND HOSPITAL

PHARMACY)

Objective: The objective of the subject is to get the students acquainted with dispensing

pharmacy practices, community pharmacy practices and structure of hospital pharmacy.

S.No. Topic No. of

Classes

1. Prescription: Parts, types and handling of prescription, knowledge of

commonly used Latin terms in prescriptions, general dispensing and

compounding procedures, labeling of dispensed products, sources of

errors in prescription, care required in dispensing of prescription.

9

2. Pharmaceutical calculations: Different systems of weights and

measures, dilution and concentration of solutions, percentage solutions,

calculation by allegation, proof spirits, isotonic solution, calculation for

adjustment to isotonicity, posology, knowledge of prophylactic and

therapeutic doses of commonly used drugs, detection of overdoses in

prescription, calculation of doses for infants, adults and elderly patients.

9

3. Principle involved and procedures adopted in dispensing of mixtures,

solutions, emulsions, lotions, liniments, powders, capsules, tablets,

tablet triturates, pastilles, lozenges, pills, ointments, creams, pastes,

suppositories, jellies, inhalations, paints, sprays and ophthalmic

preparations.

8

4. Incompatibility: Physical, therapeutic and chemical incompatibilities,

incompatibility of common occurrence and their correction.

8

5. Community pharmacy: Organization and structure of retail and whole

sale drug store and design, legal requirements for establishment and

maintenance of drug stores, dispensing of proprietary products,

maintenance of records, patient counseling on rational use of drugs and

aspects of health care.

3

6. Hospital pharmacy: Organization of a hospital pharmacy,

responsibilities of a hospital pharmacist, pharmacy and therapeutic

committee, hospital formulary, contents, preparation and revision of

hospital formulary, inventory control procedures in hospital pharmacy.

3


303T: PHARMACEUTICAL ANALYSIS-I

Objective: The objective of this course is to provide students with a breadth of knowledge in the current

trends in pharmaceutical analysis. Analysis of pharmaceuticals play a very important role in

industry as it relies upon both qualitative and quantitative chemical analysis to ensure that the

raw material used meets Pharmacopoeial specifications and also ensures a quality of finished

product in terms of proportion of components. The subject pharmaceutical analysis is

designed and distributed into three levels as Pharmaceutical Analysis I, II and III. The aim of

the course pharmaceutical analysis I is to study the various techniques employed in analyzing

pharmaceuticals. The course encompasses the methods of production of analytical data,

which is related to quality of the product assured by employing non instrumental techniques.

On completion of this course, a candidate should be able to identify, formulate, analyze and

solve problems in the analysis of chemical compounds.


1.

Theoretical aspects of quantitative analysis: Significance of quantitative analysis in quality control:

Different techniques of analysis Statistical treatment of analytical data Types of errors Mean deviation Standard deviation Accuracy and precision Significant figures, rules for retaining significant figures,

methods of expressing concentration Primary and secondary standards

02

2. Acid Base titration: Acid base concepts Role of solvents Relative strengths of acids and bases Ionization Law of mass action Common-ion effect Ionic product of water pH, hydrolysis of salts, Handerson-hesselbach equation Buffer solutions Neutralization curves Acid-base indicators Theory of indicators, choice of indicators Mixed indicators Universal indicators Polyprotic systems Preparation and standardization of neutralization titrants.

08

3. Redox titrations Concepts of oxidation and reduction, Redox reactions Strengths and equivalent weights of oxidizing and reducing

08

agents Theory of redox titrations Redox indicators Oxidation reduction titration curves

Titrations involving : Potassium permanganate Cerric ammonium sulphate Potassium iodate Potassium bromate Iodometry and iodimetry

Standardization of redox titrants like: Potassium permanganate Cerric ammonium sulphate Potassium dichromate Potassium iodate, potassium bromated Iodine Sodium thiosulphate.

4. Precipitation titrations: Solubility products Detection of end point in precipitation titrations, indicators

used in precipitation titrations Preparation and standardization of titrants like:

Silver nitrate, Ammonium potassium thiocyanate Titrations according to Mohr’s and Volhard’s methods

Ammonium and potassium thiocyanate Applications in pharmaceutical analysis

08

5. Gravimetric analysis: Fundamentals of gravimetry Precipitation reagents, precipitation techniques,

Specific examples of gravimetric estimation like: Aluminium as hydroxy quinolate Barium as barium sulphate Lead as chromate Magnesium as magnesium pyrophosphate

05

6. Non aqueous titrations: Scopes and limitations Solvents used in non-aqueous titrations Acid-base equilibria in non aqueous media differentiating

and leveling effect of solvents Preparation and standardization of perchloric acid and

tetrabutyl ammonium hydroxide Titration of weak acid and weak bases with suitable

examples.

05

7. Complexometric titrations: Theory of complexometric analysis, factors influencing

stability of complexes Metal ion indicators Types of disodium edetate titrations with suitable examples Preparation and standardization of disodium edetate,

methods to increase the selectivity of EDTA titrations.

04


304T: PHARMACOGNOSY-I

Objective:

To provide a rational relationship between chemical moieties of naturally occurring drugs and biological and therapeutic effects they produce.

To provide information about cultivation technology, chemistry of bio-constituents, biogenesis and therapeutic efficacy of crude drugs.


1. Definition, history, scope and development of Pharmacognosy.

Sources of Crude drugs and methods of their classification.

5

2. Plant hormones and their applications. Influence of Mutation and

hybridization with reference to medicinal plants.

4

3. Pest control and natural pest control agents. 3

4. Quality control of crude drugs: Different types of adulteration

and their evaluation using various methods like organoleptic,

microscopic, physical, chemical and biological.

6

5. An introduction of various types of primary and secondary

metabolites as active constituents of crude drugs, General

methods of their isolation, classification, properties and

systematic pharmacognostic study of -

a) Cararbodydrates and drugs belonging to this class like: Agar,

Guar gum, Acacia, Isabgol, Pectin, Sterculia, Tragacanth.

6

6. b) Libids and drugs belonging to this like: Castor oil. Beeswax,

Cocoa butter, Hydonocarpus oil, Kokum butter, Codliver oil,

Woolfat.

6

7. c) Resins and Tannins, and drugs of these classes like Podophyllum, Balsams, Turmeric, Ginger, Ipomea and Myrobalan

6

8. Pharmaceutical aids like: Talc, Kaolin, Bentonite, Gelatin,

Cotton and Viscose Rayon.

4


305T: ANATOMY, PHYSIOLOGY AND HEALTH EDUCATION – II

Objective: As the result of instructional activities, students will be able to: ANATOMY 1. discuss the organization of the human body in anatomic terminology 2. discuss the vertebrate/mammalian body plan 3. discuss the location of body cavities and membranes, cells, tissues, organs, organ systems 4. compare and contrast the gross and microscopic anatomy of the cells, tissues, organs, and organ systems of the body 5. compare and contrast the normal microanatomy of the four basic tissue types (epithelia, connective, muscle, nervous) and their fifteen subtypes with attention to the details of cellular and intracellular morphology, stratification, nature of the interstitial material and anatomic location in the organ systems under study via: lecture material, demonstrations, and web-based searches 6. direct visualization in the lab using light microscopes and electron micrographs 7. compare and contrast the normal gross and microscopic anatomy of the body organs and organ systems (gastrointestinal, respiratory, urinary, and reproductive) with emphasis on the size, shape, internal architecture, microanatomy, anatomic relationships, and locations via: lecture material, demonstrations, and internet searches; dissection of lab specimens: preserved mammalian organs and the organ systems of cats, fetal pigs; observation of human organs (pathologic specimens) 8. discuss the chemical structure of biologically important small molecules and macromolecules which serve as catalysts, chemical messengers (hormones), cell receptors, ion channels, neurotransmitters, transport molecules, antibodies, and structural components of cells, tissues, and organs 9. present the concept of differential diagnosis as a major critical thinking tool in the understanding of, and application of, anatomic and physiologic principles in health and disease 10. demonstrate and discuss the clinical implications of structural deviations from normal gross and microscopic anatomy associated with pathologic states (disease) PHYSIOLOGY 11. explain the functions (physiology) of the body molecules, cells and organelles, tissues, organs, and organ systems 12. explain the chemical and physical principles which underlie molecular, cellular, tissue, organ, and organ system physiology for the systems under study 13. present structure/function correlations at the chemical, cellular, tissue, organ, and organ system levels for the systems under study 14. stress the importance of homeostasis and discuss homeostatic mechanisms in detail which maintain the normal internal environment consistent with life (maintenance of blood pressure, blood glucose, fluid and electrolyte balance, acid/base balance, body temperature) 15. investigate physiologic functions by direct participation in laboratory experimentation, data collection, and analysis.


1. Central Nervous System: Functions of different parts of brain and spinal cord. Neurohumoral transmission in the central nervous system, reflex action, electroencephalogram and specialized function of the brain. Cranial nerves and their functions.

6

2 Autonomous Nervous System: Physiology and functions of the autonomous nervous system. Mechanism of neurohumoral transmission in the automatic nervous system.

5

3 Respiratory System: Anatomy of respiratory organs, functions of respiratory organs, mechanism and regulation of respiration, respiratory volumes and vital capacity.

5

4 Endocrine System: Basic anatomy and physiology of pituitary, thyroid, parathyroid, adrenals, pancreas, testis and ovary; their hormones and functions.

5

5 Digestive System: Gross anatomy of gastrointestinal tract, functions of its different parts, various gastrointestinal secretions and their role in the absorption and digestion of food.

5

6 Reproductive System: Anatomy of male & female reproductive system and their hormones, physiology of menstruation, coitus, infertilization, sex differentiation, spermatogenesis and oogenesis, pregnancy its maintenance and parturition.

5

7 Urinary System: Various parts, structures and functions of kidney and urinary tract, physiology of urine formation and acid-base balance.

5

8 Sense Organs: Basic anatomy and physiology of the eye (vision), ear (hearing), taste buds, nose (smell) and skin (superficial receptors).

4


306 P: COMMUNICATION SKILLS & PERSONALITY DEVELOPMENT-III

Objective: This course aims to help an individual maximize available resources to reach a person’s full

potential through a well-rounded and groomed personality. The subject is aimed at the

promotion of the strategies for the personality development of the participants. The rationale

behind this endeavor is the recognition of the multifaceted influence of the personality of the

employees upon organizational effectiveness. The purpose behind the inclusion of this

subject is to bring about personality development with regard to the different behavioral

dimensions that have far reaching significance in the direction of organizational

effectiveness. This subject is designed to help people in organizations who wish to gain

confidence and effectively perform in the professional environment.


1.

Professional correspondence:

12

Memos

Components of a memo

Organization

Development

Language and tone of a memo

Memo formats

Types of memos

Status memos

Negative memos

Personal memos

Memos of transmittal

2. Resume and curriculum vitae:

08

Types of resume

Design of resumes

Writing job application letters

Organization approaches to letters of application

Resumes follow-up correspondence


B. PHARM. SEMESTER-V

501 T: PHARMACEUTICS- VI (COSMETIC TECHNOLOGY)

Objective:

This subject aims to provide students with fundamental knowledge of cosmetic science. It

deals with the formulation considerations, preparation, packaging and evaluation of the

cosmetic preparations.

S.No. Topic No. of

Classes

1. Face preparation: Face powder, compact powder, talcum powder, face packs

and masks.

04

2. Colored make-up preparations: Lipsticks, rouge, mascara, and eye liner. 04

3. Skin preparation: Skin creams, vanishing creams, cold creams, all purpose cream, cleansing creams, emollient, anti-perspirant/ deodorant, moisturizing and foundation formulation, bleaching creams, night and massage creams, anti-wrinkle preparation, hand creams, protective skin tonics, skin moisturizers, sun-screen preparation.

08

4. Shaving preparation: Lather shaving stick, lather shaving creams, shaving foams, shaving gels, pre-and after shave lotions.

03

5. Shampoos: Clear liquid shampoos, acid-balanced shampoos, egg shampoos, anti-dandruff shampoos.

03

6. Hair preparations: Hair tonics, hair conditioners, hair lotions, hair sprays, hair

dressings, hair setting lotions and creams, hair dyes, bleaches, hair waiving,

hair straightners and hair strengtheners.

06

7. Dental preparation: Tooth powders, tooth pastes, dentifrice, cleansers and mouth washes.

04

8. Manicure preparation: Nail polish, nail lacquers and nail bleaches. 02

9. Herbal cosmetics: Cosmetics containing aloe, babul, brahmi, chandan,

cucumber, haldi, jatamansi, khus, mehandi, neem, reetha, shikakai, tulsi,

arnica, bhringraj and volatile oils.

08

10. 10. Cosmetic for babies: Baby cream, lotion and powders.

02


502 T: PHARMACEUTICS-VII (PHARMACEUTICAL TECHNOLOGY-I)

Objective:

To Demonstrate an in-depth understanding of various dosage forms and drug delivery

systems

demonstrate a systematic and critical understanding of dosage form formulation and their

Technology

To make students aware with the new trends in dosage form development research

S.No. Topic No. of Classes 1 Liquid Dosage Forms: Introduction, types of additives used in

formulations, vehicles, stabilizers, preservatives, suspending

agents, emulsifying agents, solubilizers, colors, flavors and

others, manufacturing, packaging and evaluation of clear liquids,

suspensions and emulsions.

5

2 Semisolid Dosage Forms: Definition, types and mechanisms of

drug penetration. Factors influencing penetration. Semisolid bases

and their selection. General formulation of semisolids, clear gels,

manufacturing procedure, evaluation and packaging.

5

3 Suppositories: Ideal requirements, bases, manufacturing

procedures, packaging and evaluation 3

4 Solid Dosage Forms: Tablets: a. Formulation of different types of

tablets, granulation technology on large scale by various

techniques, different types of tablet compression, machinery and

the equipments involved, evaluation of tablets.

b. Coating of tablets: Types of tablet coating, film forming

materials, formulation of coating solutions, equipments of

coating, coating process, evaluation of coated tablets.

10

5 Solid Dosage Forms: Capsules: Advantages and disadvantages of

capsules dosage form, material for production of hard gelatin

capsules, size of capsules, methods of capsule filling and sealing,

soft gelatin capsule, capsule shell and capsule content, importance

of base adsorption and minim per gram factors in soft gelatin

capsules, quality control, stability studies and testing of capsule

dosage form.

8

6 Pharmaceutical aerosols: Definition, propellants, and general

formulation, manufacturing and packaging methods and

pharmaceutical applications.

6

7 A brief introduction of blood products, plasma substitutes and

surgical products. 3


503 T: PHARMACEUTICAL CHEMISTRY-V (MEDICINAL CHEMISTRY-I) Objectives:

Pharmaceutical Chemistry-V (Medicinal Chemistry-I) subject is designed to expose

undergraduate pharmacy (B.Pharm) students to the history, theory and practice of Medicinal

Chemistry. This introductory subject will emphasize basics of medicinal chemistry, drug

design and development, structure-activity relationship, biochemical mechanism of action of

drugs, drug synthesis and applications of medicinal chemistry. In particular, the molecular

aspects of drug action (chemical, physical, and biological) will be discussed in detail.

At the completion of this subject:

1. The student should be able to understand and relate basic concepts in a variety of

therapeutic (drugs) classes to their biological action.

2. The student should know the biochemical basis for some of the known mechanisms of drug

action.

3. The student should understand the role of molecular modification (structure-activity

relationship) in the development of new drugs; its successes, shortcomings and failures.

4. The student should be able to relate chemical structure to biological availability, biological

activity, and routes of delivery/metabolism for some of the more important pharmacological

classes.

S.No. Topic No. of

Classes

1. Introduction and basic principles of Medicinal Chemistry:

Historical perspectives of Medicinal Chemistry, Drug discovery (1)

Physico-chemical, stereochemical (optical and geometrical) properties and

bioisosterism in relation to biological action (1), receptors and drug action,

theories and drug receptor interactive forces (3), Enzymes and drug action

(2), Drug metabolism, Phase I and Phase II reactions (3)

10

Classification, synthesis of selective drugs, Structure activity relationship,

pharmacological/biochemical mechanism of action, Therapeutic uses of following

category of agents: (special emphasis should be given to specified drugs)

2. Drugs affecting neurotransmission:

2a. Drug acting on cholinergic neurotransmission:

Neurochemistry and stereochemistry of acetylcholine (1), Cholinergic, anti-

cholinergic, anti-cholinesterase agents (2) and neuromuscular blocking

agents (1) (Acetylcholine chloride, Carbachol chloride, Atropine,

05

Pyridostigmine bromide, Succinyl choline chloride and Tropicamide) (1).

2b. Drug acting on adrenergic neurotransmission:

Neurochemistry and stereochemistry of Norepinephrine, Adrenergic agents,

Sympathomimetic agents, Adrenergic receptor antagonists (Ephedrine,

Epinephrine, Isoprenaline, Phenylpropanolamine hydrochloride and

Propanolol).

05

2c. Drug acting on seratonergic neurotransmission:

Neurochemistry and stereochemistry of Serotonin, Seratonergic agonists

and antagonistic agents.

03

2d. Local Anesthetic agents:

Benzocaine, Procaine hydrochloride, Lignocaine hydrochloride,

Bupivacaine hydrochloride, and Dibucaine hydrochloride.

02

3. Drugs affecting the Immune System:

3a. 3a. Non-steroidal anti-inflammatory agents, analgesics and anti-pyretic:

Chemistry of inflammatory mediators, Prostaglandins, Leukotrienes and

Thromboxanes (Asprin, Acetaminophen, Indomethacin, Ibuprofen,

Naproxen, Piroxicam, Phenylbutazone, Oxyphenbutazone and Celecoxib).

04

3b. Antihistamines, anti-allergic and anti-ulcer agents:

Neurochemistry and stereochemistry of histamine, Dual acting anti-

histaminics, H2 and H3 antagonists (Diphenhydramine Hydrochloride,

Bromodiphenhydramine Hydrochloride, Chlorcyclizine Hydrochloride,

Promethazine Hydrochloride, Phenindamine Tartrate and Chlorpheniramine

Maleate).

05

4. Drugs affecting the Respiratory System:

Anti-asthmatics, Expectorants and Anti-tussive, agents (Salbutamol,

Terbutaline, Acetylcysteine, Bromhexine Hydrochloride, Guaifensin, and

Levopropoxyphene Napsylate).

03

5. Miscellaneous agents:

5a. Diagnostic and Medicinal dyes (Congo Red, Evans Blue, Erythrosine

Sodium, Iodipamide Meglumine, Phenolsulphonphthalein, Indocyanin

Green And Fluorescein, Sodium).

01

5b. Pharmaceutical aids. 02

General Discussion, revision of topics, and Quiz 05


504T: PHARMACOGNOSY III

Objective:

To provide a rational relationship between chemical moieties of naturally occurring drugs and biological and therapeutic effects they produce.

To provide information about cultivation technology, chemistry of bio-constituents, bio- -genesis and therapeutic efficacy of crude drugs.

S.No. Topic No. of

Classes

1. Systemic study of source, cultivation, collection, processing, commercial

varieties, chemical constituents, substitutes, adulterants, uses, diagnostic

macroscopic and microscopic features and specific chemical tests of following

Alkaloid containing drugs: a.Tropane: Belladona, Hyoscyamus, Datura, Coca

and Withania Quinoline and Isoquinoline: Cinchona, Ipecac, Opium

8

2. b. Indole: Ergot, Rauwolfia, Catharanthus, Nux-vomica, Physostigma 5

3. c. Steroidal: Veratrum, Kurchi .

d. Steroidal amine: Ephedra, Colchicum

e.Purines: Coffee, Tea and Cola

4

4. A brief account of plant-based industries and institutions involved in work on

medicinal and aromatic plants in India. Utilization and production of

phytoconstituents such as Quinine, Calcium sennosides, Podophyllotoxin,

Diosgenin, Solasodine and Tropane alkaloids

5

5. Utilization of aromatic plants and derived products with special reference to

Sandalwood oil, Mentha oil, Lemon grass oil, Vetiver oil, Gentium oil and

Eucalyptus oil

5

6. Marine pharmacognosy novel medicinal agents from marine sources. 3

7. Introduction, classification and study of different chromatographic

methods and their applications in evaluation of herbal drugs.

5

8. Holistic concept of drug administration in traditional systems of

medicine, introductions to ayurvedic preparations like arishtas, asavs,

gutikas, tailas, churans, lehyas and bhasmas.

5


505T: PHARMACOLOGY-I Objectives

The central goal of the Pharmacology and Therapeutics course is two-fold. First, to provide students with a solid grounding in the basic concepts and scientific underpinnings of Pharmacology. Second, to provide students with a comprehensive introduction to the fundamental Pharmacology and uses of the major classes of clinically important drugs currently used in medical practice.

Specific key concepts and learning objectives will be provided for each individual lecture topic. However, the general course goals are as follows:

• To understand the fundamental scientific principles of drug action and the various mechanisms by which drugs can mediate their pharmacological effect

• To understand the fundamental principles of pharmacokinetics that underly the absorption, distribution, metabolism and elimination of drugs in the body and thereby affect drug effectiveness

• To understand the biochemical reactions that result in the metabolism of drugs within the body

• To understand the rationale behind designing different dosing regimens of particular drugs in specific patient populations

• To understand how specific patient characteristics and genetics can affect the response to a particular class of drugs

• To understand the scientific basis underlying how two different drugs can interact within the body and can have undesirable effects either on drug concentrations or drug clinical effects


01 General Pharmacology a. Introduction to pharmacology, sources of drugs, dosage forms and routes of administration, mechanism of action, combined effects of drugs, factors modifying drug action, tolerance and dependence, pharmacogenetics. b.Absorption, distribution, metabolism and excretion of drugs, principle of basic and clinical pharmacokinetics adverse drug reactions and treatment of poisoning, ADME drug interactions, receptors, bioassay of drugs and biological standardization, discovery and development of new drugs. Introduction to clinical trials, bioavailability and bioequivalence studies.

10

02 Pharmacology of peripheral nervous system a. Neurohumoral transmission (autonomous and somatic) b.Parasympathomimetic,parasympatholytic andsympathomimetics. c. Adrenergic receptors and neuron blocking agents, ganglionic stimulants. And blocking agents. d. Neuromuscular blocking agents. e. Local anaesthetic agents.

06

03 Pharmacology of drugs acting on gastrointestinal tract a. Antacids, anti-secretory and anti-ulcer drugs (pathophysiology of ulcer).

06

b. Laxatives and anti-diarrhoeal drugs c.Appetite stimulants and suppressants. d. Emetics and anti-emetics. e. Carminatives, demulcents, protectives, adsorbents, astringents, digestants, enzymes and mucolytics.

04 Autacoids: a. Histamine, bradykinin, 5- HT and their antagonists. b. Prostaglandins, leukotrienes and platelet activating factors. c.Pentagastrin, cholecystokinin, angiotensin, bradykinin and substace P

06

05 Analgesic, antipyretic, anti-inflammatory (vascular and cellular events of acute inflammation, chemical mediators of inflammation, pathogenesis of chronic inflammation), anti-gout and anti rheumatic drugs (pathophysiology of gout and rheumatoid arthritis)

10

06 Pharmacology of drugs used for respiratory system: Anti-asthmatic drugs (pathophysiology of asthma) including bronchodilators, antitussives, expectorants and respiratory stimulants.

05


506 P: COMMUNICATION SKILLS & PERSONALITY DEVELOPMENT-V Objective:

To Develop the communication skills and personality of the student

Understanding of the modules of Oral business communication and Non-verbal business communication, dos and dont’s to be followed and how can student best prepare for verbal and non-verbal business communication.

S.No. Topic No. of

Classes

1. Oral business communication: Characteristics of effective oral

communication, oral communication skills, components of oral effective

communication, barriers to effective oral communication, difference

between oral and written communication, tools for oral communication.

5

2. Non-verbal business communication: Introduction of non-verbal business

communication, characteristics of non-verbal business communication,

nature and significance of non verbal business communication, relation

between verbal and non-verbal communication. (Seminars on related

topics)

5


B. PHARM. SEMESTER-VII 701T: PHARMACEUTICS -X (BIOPHARMACEUTICS AND

PHARMACOKINETICS)

Objective: The objective is to understand the effects of factors that influence the rate and extent of

drug reaches the systemic circulation and the use of this information to optimize the therapeutic efficacy of the drug products.

At the end of the course, the student shall have acquired the competency in the selection of the proper dosage form and the design of dosage regimen to optimize drug therapy in patients on the basis of their disease conditions and the drug's pharmacokinetics.

S.No. Topic No. of

Classes

1. Introduction: Definition and significance of biopharmaceutics in formulation

development.

02

2. Gastrointestinal absorption of drugs: Passage of drugs across biological

membranes nature of biological membranes, gastrointestinal absorption

mechanism.

03

3. Factor affecting drug absorption: Physiological factors, dietary factors, physicochemical factors, pH partition hypothesis, and dosage form factors.

07

4. Methods of studying gastrointestinal absorption: In vitro and in vivo methods. 02

5. Drug disposition: Distribution in blood, cellular distribution, plasma protein binding, tissue protein binding.

03

6. Drug excretion: Routes of drug excretion, renal excretion of drugs, factors affecting renal excretion, biliary and salivary excretion of drugs.

04

7. Drug biotransformation: Pathways of drug metabolism, drug metabolizing, enzymes, and factors affecting drug metabolism, inhibition and stimulation of drug metabolism.

05

8. Definition and need of pharmacokinetic and clinical pharmacokinetics. 01

9. Introduction to pharmacokinetic parameters, biological half-life, volume of distribution, clearance, rate constants for elimination.

02

10. One compartment model: Single dosing-intravenous injection and oral absorption, determination of pharmacokinetic parameters from plasma and urine data, measurements of Cmax, Tmax, and AUC.

08

11. Bioavailability and bioequivalence: Definition and detailed protocol, significance of bioavailability and bioequivalence studies, and Regulatory requirements.

05


702 T: PHARMACEUTICAL CHEMISTRY-VII (MEDICINAL CHEMISTRY-III)

Objectives:

Pharmaceutical chemistry-VII (Medicinal Chemistry-III) subject is designed to expose Final

Year undergraduate pharmacy (B.Pharm) students to the advanced level of theory and

practice of Medicinal Chemistry. This subject will emphasize various aspects of medicinal

chemistry, drug design and development, structure-activity relationship, biochemical

mechanism of action of drugs, drug synthesis. In particular, the molecular aspects of drug

design and drug action (chemical, physical, and biological) will be discussed in detail.

Special emphasis will be taken on the computer-aided drug design (CADD) methods used by

Medicinal Chemists to design and develop new drugs.

At the completion of this subject:

1. The student should be able to understand basic concepts of CADD, QSAR, molecular

modeling and its applications in drug discovery and development.

2. The student should understand the role of de novo and molecular modeling techniques

in the development of new drugs.

3. The student should know the pharmacological/biochemical basis for some of the

known (antibiotics, antibacterial agents, antiviral agents, antifungals, antiparasitic

agents, antitubercular agents) mechanisms of drug action.

4. The student should understand the role of molecular modification in the development

of new drugs; its successes, shortcomings and failures.

5. The student should be able to relate chemical structure to biological availability,

biological activity, and routes of delivery/metabolism for some of the more important

pharmacological classes.


1. Drug Design and Development: Relationship of functional groups to pharmacological activity,

Prodrug Design,

Analog Design,

Topliss Tree Approach,

Craig’s Plot

03

Quantitative Structure Activity Relationship (QSAR):

Hansch Analysis,

Free Wilson Analysis,

03

Fujita Ban Approach,

Topological QSAR,

3D QSAR Approaches,

Applications and case study related to QSAR

Introduction to Computer Aided Drug Design:

Molecular Mechanics, Quantum Mechanics, De-Novo Design,

Ligand based design, Structure based drug design,

03

2. Modern Medicinal Chemistry:

Introduction to Combinatorial Chemistry, High throughput

screening, Green Chemistry and Microbial biotransformation.

03

Classification, synthesis of selective drugs, Structure-

activity relationship, Pharmacological/Biochemical

mechanism of action, Therapeutic uses of following

category of agents: (special emphasis should be given to

specified drugs)

3. Drugs affecting the Cardiovascular System:

a. Anti-anginal and Vasodilators: Amylnitrate, Nitroglycerin,

Isosorbide Dinitrate, Verapamil, Diltiazem, Nifedipine,

Amlodipine, Digoxin, and Digitoxin.

b. Anti-arrhythmic agents: Quinidine Sulphate, Procainamide

Hydrochloride, Lidocaine Hydrochloride and Phenytoin

Sodium.

c. Antihypertensive agents: Captopril, Enalapril, Quinapril

Hydrochloride, Losartan, Reserpine, Guanethidine, Clonidine

Hydrochloride, Hydralazine Hydrochloride, Sodium

Nitroprusside and Minoxidil.

d. Antihyperlipidemic agents: Clofibrate, Gemfibrozil,

Atorvastatin, Lovastatin, Dextrothyroxine Sodium,

Cholestyramine Resin, Niacin and Probucol.

06

4. Drugs affecting the Urinary System:

Diuretics: Chlorothiazide, Hydrochlorothiazide, Cyclothiazide,

Cyclopenthiazide, Methylclorthiazide, Trichlormethiazide,

Acetazolamide, Methazolamide, Ethozolamide, Furosemide,

Ethacrynic Acid and Triamterene.

03

5. Chemotherapeutic agents:

(I) Antibacterial agents:

(a) Sulphonamides :

Sulphanilamide, Sulphapyridine, Sulphathiazole,

Sulphadiazine, Sulpharmerazine, Sulphadimidine and

Dapsone.

(b) Antibiotics: Penicillin V, Cloxacillin Sodium, Cephazolin

Sosium, Chloramphenicol, Aminoglycosides (Streptomycin,

Neomycin and Kanamycin), Macrocyclics (Erythromycion,

Clarithromycin and Roxithromycin), Tetracyclines,

Vancomycin, Valinomycin, Polymyxin and Flouroquinolones.

(II) Antiparasitic agents: Antiprotozoal and Anthelmentic

agents.

(a) Antimalarial drugs: Chloroquine Phosphate, Amodiaquine,

Pamaquine, Pentaquine Phosphate, P-Chloroproguanil

Hydrochloride, Cycloguanyil Embonate, Pyrimethamine and

Trimethoprim.

(III) Antifungal agents: Fluconazole, Tolnaftate, Clotrimazole,

Miconazole, Ketoconazole, Fluconazole, Amphotericin-B,

and Griseofulvin.

(IV) Antimycobacterial agents: Pyrazinamide, Rifampin,

Ethambutol Hydrochloride, Isoniazid and Ethionamide.

(V) Anticancer agents, Immunosupressants and

Immunostimulants : Cyclophosphamide, Chlorambucil,

Busalfan, Methotrexate, Azothiopurine, Cytarabine,

Fluorouracil, Methotrexate, Dactinomycin, Daunorubicin

Hydrochloride, Doxorubicin Hydrochloride, Etoposide,

Vinblastin Sulphate, Vincristin Sulphate and Cisplatin.

(VI) Antiviral including anti-HIV agents: Amantadine

Hydrochloride, Rimantadine Hydrochloride, Idoxuridine

Trifluoride, Acyclovir, Gancyclovir, Zidovudine and

Ritonavir.

(I) – 05

(II) – 04

(III) – 01

(IV) – 02

(V) – 04

(VI) – 03

6. General Discussion, revision of topics, and Quiz 05


703T: PHARMACEUTICAL ANALYSIS-III

Objectives: To understand the basic principles, instrumentation and applications of

instrumental methods of analysis with emphasis on interpretation of UV, IR, NMR, Mass

Spectra & HPLC and HPTLC Chromatograms.

S.No. Topic No. of

Classes

1.

UV-visible spectroscopy: Brief review of electromagnetic spectrum and absorption

of radiations, the chromophore concept, Lambert-Beer’s law and its deviations,

theory of electronic spectroscopy, transitions in UV, Absorption bands in UV,

absorption by organic molecules, choice of solvent and solvent effects, modern

instrumentation – design and working, Applications of UV-visible spectroscopy

(qualitative and quantitative analysis), Woodward -Fischer rules for calculating

absorption maximum.

04

2.

IR-spectroscopy: Introduction, basic principles, vibrational frequency and factors

influencing vibrational frequency, instrumentation and sampling techniques,

Interpretation of IR spectra and applications.

04

3.

Atomic absorption spectroscopy: Theory of absorption of radiant energy by atoms,

instrumentation, and analytical applications.

02

4.

Photoluminescence: Fluorescence and phosphorescence: Theory, instrumentation

and pharmaceutical applications

03

5.

Flame photometry: Theory of emission spectra, instrumentation, and qualitative

and quantitative applications.

02

6.

Nuclear magnetic resonance: An introduction to the theory of NMR (PMR),

chemical shifts, factors affecting chemical shift, spin-spin coupling, coupling

constant, factors affecting of coupling constant, NMR instrumentation, A brief

introduction to C13-NMR, applications of PMR.

05

7.

Mass spectrometry: Theoretical aspects, basic principles, instrumentation,

ionization techniques, the mass spectra, types of ion, determination of molecular

formula, molecular weight, fragmentation rules (basics including Nitrogen rule,

Mc Lafferty arrangement), interpretation of mass spectra and applications.

06

8.

Chromatographic methods: Basics of chromatography, Principle, Theory,

instrumentation and applications involved in Column chromatography, Paper

03

chromatography, Ion-exchange and Gel filtration techniques.

9.

Thin Layer Chromatography (TLC) and High Performance Thin Layer

Chromatography (HPTLC): Theory and Principle, instrumentation, elution

techniques, method development, common detectors, visualizing agents and

pharmaceutical applications.

04

10.

High Performance Liquid Chromatography: Principle, instrumentation, solvents,

sample preparation, pre and post column derivatisation, elution techniques,

reversed phase HPLC, applications in Pharmacy.

04

11.

Gas chromatography: Theory and principle, instrumentation, sample injection

system, Detectors (TCD, FID, ECS, FPD) and applications in pharmacy.

03


704T: PHARMACOLOGY-III

Objectives

The central goal of the Pharmacology and Therapeutics course is two-fold. First, to provide students with a solid grounding in the basic concepts and scientific underpinnings of Pharmacology. Second, to provide students with a comprehensive introduction to the fundamental Pharmacology and uses of the major classes of clinically important drugs currently used in medical practice.

Specific key concepts and learning objectives will be provided for each individual lecture topic. However, the general course goals are as follows:

• To understand the fundamental scientific principles of drug action and the various mechanisms by which drugs can mediate their pharmacological effect

• To understand the fundamental principles of pharmacokinetics that underly the absorption, distribution, metabolism and elimination of drugs in the body and thereby affect drug effectiveness

• To understand the biochemical reactions that result in the metabolism of drugs within the body

• To understand the rationale behind designing different dosing regimens of particular drugs in specific patient populations

• To understand how specific patient characteristics and genetics can affect the response to a particular class of drugs

• To understand the scientific basis underlying how two different drugs can interact within the body and can have undesirable effects either on drug concentrations or drug clinical effects

S.No. Topic No. of

Classes

1 Pathophysiology of microbial diseases (Tuberculosis, leprosy, fungal diseases,

urinarytract infections, sexually transmitted diseases) and pharmacology of

drugs used for their treatment

5

(i) General principles of Chemotherapy 2

(ii) Sulfonamides and cotrimoxazole 1

(iii) Antibiotics: Penicillins, Cephalosporins, Aminoglycosides, Chloramphenicol,

Macrolides, Tetracyclines, Quinolones, fluoroquinolones and Miscellaneous

antibiotics

4

(iv) Anti-mycobacterial drugs 4

(v) Anti-viral and anti-HIV drugs 3

(vi) Anti-malarial drugs 2

(vii) Drugs for amoebiasis and other protozoal infections 1

(viii) Anthelmentics 1

2 Pathophysiology of Cardiovascular diseases (Hypertension, angina, congestive

heart failure, atherosclerosis, myocardial infarction) and pharmacology of drugs

used for their treatment.

3

(i) Cardiac glycosides 1

(ii) Antiarrhythmic drugs 2

(iii) Antianginal drugs 2

(iv) Antihypertensive drugs 2

(v) Anti-hyperlipidemic drugs 1

(vi) . Anti-neoplastic drugs (pathophysiology of cancer), immunostimulants and

immunosuppressive agents.

4

(vii) Drugs acting on urinary system: Diuretics 2


705 P: COMMUNICATION SKILLS & PERSONALITY DEVELOPMENT-VII

Objectives:

Developing grammmer, vocublary and mechanics for communicative English. Developing english reading skills and comprehending. Understanding of body language and its usage.


1. Orientation class 1

2. Points on interview preparation 1

3. Preparing Biodata 1

4. Formal interview 1

5. Informal interview 1

6. Answering strategies 2

7. Interview through tele and video-conferencing 2

8. Mock interviews. 2

9. Features of time management 2

10. Personal time management, 3

11. Project development, 2

12. Group management 1

13. Concluding class 1


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