Bookman.GIRLeadInstitute.2016.v3.distro

The research mission…...in contexts

richard j. bookman, [email protected]@rbookmanhttp://slideshare.net/rbookman

2016 AAMC GIR Leadership Institute2 March 2016

http://www.gerhardrichterpainting.com/wp-content/uploads/2012/01/gerhardrichter_photo3.jpg

mailto:[email protected]

disclosures

I have no financial interest in any of the content presented today.

learning objectives

• Understand the current operating model of research in an AMC, how it got that way, and where it might be going.

• Understand some of the challenges and issues researchers, research deans, & IT teams typically face.

• Understand opportunities for IT teams to enhance both the research mission & its sustainability.

<outline>

OverturePastPresentFuture

</outline>

research is a human activity

http://www.stanford.edu/group/vista/cgi-bin/FOV/wp-content/uploads/2012/02/tables1.png

“Science is the belief in the ignorance of experts.”

Richard Feynman,“What is Science?”, address to science teachers, 1966

http://img.youtube.com/vi/_ah7f-1M2Sg/hqdefault.jpg

</overture>

<research.past>

research 1.0

//who is doing it?//where are they doing it?//how is it organized?//who is paying?//how are results communicated?

http://pics-about-space.com/ancient-greek-astronomy?p=3#

research does not advance unless & untilinformation

can be stored,organized, retrieved,& shared

</research.past>

<research.present>

research 2.0


“ask not what your country…”jfk,

1961 inauguration speech

http://www.nature.com/nrc/journal/v1/n3/box/nrc1201-240a_BX1.html

Vannevar Bush, Science, The Endless Frontier

"Discoveries pertinent to medical progress have often come from remote and unexpected sources, and it is certain that this will be true in the future. It is wholly probable that progress in the treatment of cardiovascular disease, renal disease, cancer, and similar refractory diseases will be made as the result of fundamental discoveries in subjects unrelated to those diseases, and perhaps entirely unexpected by the investigator. Further progress requires that the entire front of medicine and the underlying sciences of chemistry, physics, anatomy, biochemistry, physiology, pharmacology, bacteriology, pathology, parasitology, etc., be broadly developed."

http://www.aaas.org/sites/default/files/FunctionNON_0.jpg

what is the mission of an AMC?

disseminate knowledgecreate knowledge

AMC’s 3 missions

Research

Clinical CareTraining

What is the balance of missions at your institution research?

<discussion question>

</discussion question>

Hypothesis-driven vs.

discovery-driven research

3 types of research

basic

clinicaltranslational

basic


3 types of research

basic


implementationscience

public health

3 types of research

what is the balance of research types at your institution?



The research cycle…

writeproposals

publish papers

do research

Grad students & postdocs enter cycle here…

get funding

34

composition of the research team

PIPostdocsgrad studentslab techsclinical research coordinators& many others

inside the mind of a PI

researchers & administrationshare a mission

http://www.dailymail.co.uk/news/article-3045359/Tensions-close-friends-Marco-Rubio-Jeb-Bush-rise-race-White-House-heats-up.html

but don’t always see things the same way

financing the research mission

show me the moneysome key facts

• OPM is key• OPM comes in 3 main flavors:

internal cross-subsidization philanthropy grants

• NIH grants are the gold coin of the realm

• grants have both direct and indirect costs

“it’s my money, and I’ll spend it any way I like.”

https://members.aamc.org/eweb/upload/Academic%20Medicine%20Investment%20in%20Medical%20Research.pdf

regulatingthe research mission

regulatory requirements for clinical research

(after Sam Tilden, UAB)

What are the key IT pain-points for each type of research?



enhancingthe research mission

• leading edge research requires high performance, high throughput, and highly flexible computing capabilities

• regulatory environment requires role-based access to integrated data from multiple institutional (and even non-institutional) systems

• smart execution of research strategy requires tracking every detail of the research operation

• sandboxes

• interoperability is key

research does not advance unless & untilinformation

can be stored,organized, retrieved,shared, &reused!

research 2.x


</research.present>

<research.future>

research 3.0b


Terms of UseSee this page for info, including copyright

http://gowers.wordpress.com/2009/02/01/a-combinatorial-approach-to-density-hales-jewett/

http://www.google.com/intl/en-US_US/help/terms_maps.html

http://scimaps.org/maps/map/hypothetical_model_o_51/

http://www.patientslikeme.com/about

http://www.pnas.org/content/105/6/2052

http://www.nature.com/nbt/journal/v29/n5/full/nbt.1837.html

“Patient engagement is the blockbuster drug of

the 21st century”Leonard Kish

http://www.hl7standards.com/blog/2012/08/28/drug-of-the-century/

http://www.galaxyzoo.org/

how are your researchers using the internet for research or

for professional communication?any issues?



http://doi.ieeecomputersociety.org/10.1109/MIS.2009.36

to share or not to share,THAT is the question

got any issues around data-sharing?



//computable papers

research 3.0b


</research.future>

//my appeal to you

learning objectives

• Understand the current operating model of research in an AMC, how it got that way, and where it might be going.

• Understand some of the challenges and issues researchers, research deans, & IT teams typically face.

• Understand opportunities for IT teams to enhance both the research mission & its sustainability.

</body>

//thank you

Bookman.GIRLeadInstitute.2016.v3.distro

Science

Transcript of Bookman.GIRLeadInstitute.2016.v3.distro