Paragonimus westermani/kellicati

Asmerom Lebasi, Quinn Quaderer, Tamrat Oda

Classification/ Taxonomy Domain: EukaryotaKingdom: AnimaliaPhylum:Platyhelminthes

Class: TrematodaSubclass: DigeneaFamily: Paragonimidae

Genus: Parnagonimus

Species: westermani

Morphology

adult fluke has reddish-brown in color, oval in shape

looks like coffee bean

10 mm long X 5 mm wide

Geographic Distribution:• Paragonimus

westermani is distributed in southeast Asia and Japan. 

Paragonimus kellicotti is endemic to Eastern U.S. and Canada:

-rarely results in human infection

HostsDefinitive Host:• Humans (rare for P.

kellicotti )

• Cats• Dogs • Pigs

Intermediate Host: 1. Snails 2. Crabs and crayfish

.

My name is BoI am a definitive host

http://www.ochealthinfo.com/epi/imf

I ’m sooo wasted!!

LIFECYCLE

Life Cycle of Paragonimus Westermani/Kellicotti1.       Eggs are excreted unembryonated in the spit, or are swallowed and passed in the feces.

2.       In the external environment, the eggs become embryonated.

3.       Miracidia hatch and seek the first immediate host(snail) and penetrate its soft tissues.

4.       Miracidia go thru 3 life stages while in the snail: a.       Sporocysts b.      Rediae that give rise to many cercariae. c.       Cercariae emerge from the snail.

5.       Cercariae invade the second intermediate host, the crab or crayfish, where they encyst and become metacercariae. Infective stage.

6.       Humans consume undercooked or pickled crab or crayfish that have P. westermani/kellicotti.

7.       Metacercariae excyst in the duodenem.

8.       Penetrate thru the intestinal wall into the peritoneal cavity, then thru the abdominal wall and diaphragm into the lungs.

9.       Encapsulate in the lungs and develop into adults.

10.   Adults in the lungs lay eggs which are then excreted in spit or feces.

SymptomAcute phase Chronic phase

      diarrhea, Chest pain,abdominal pain, Fever cough, skin rash notable for

pale red, raised, itchy bumps

During the, pulmonary manifestations

coughdiscolored sputum hemoptysis chest radiographic

abnormalities. chronic cough

Diagnosis Microscopic detection of eggs in feces or

sputumImmunioblot for IgG antibody detectionRadiological method can be used tooX-ray the chest cavity and look for worms a lung biopsy

TreatmentPraziquantel (95% efficiency)

Prevention

• In order to prevent infection

  do not eat uncooked crab marinated in line juice because the lime do not kill the parasite

 

Public Health Concerns

More than 22 million humans have it