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The Fifth Edition of this highly acclaimed reference describes state-of-the-art laboratory methodsfor evaluating the efficacy of antibiotics and the mechanisms of bacterial resistance. Coverageincludes new molecular techniques for antibiotic testing, the new discipline of pharmacogenomics,and use of computers to monitor resistance trends. New chapters focus on the breakpoint,molecular techniques for susceptibility testing, susceptibility testing of HIV and hepatitis agents toantiviral drugs, and disinfectant and antiseptic testing. Sixteen new antimicrobial agents most FDA-approved, others German and UK-approved are examined. More than 200 tables provideinformation on every organism, every antimicrobial agent, and drug concentrations in blood,organs, and tissues.

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