Analyzing yourhealthcare data fora better you0b804eb0-c448-4b7d... · Proliferation of medical...
Transcript of Analyzing yourhealthcare data fora better you0b804eb0-c448-4b7d... · Proliferation of medical...
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Analyzingyour healthcaredatafor abetteryou
KuldeepSinghRajput,Founder&ChiefExecutiveOfficer
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50MORETHAN
%
OFTHEWORLDLIVESWITHCHRONICDISEASES
…trilliondollarproblem – economiccrisis
OfallAmericans50 andolder
outof HAVE7 10TWOORMOREchronichealthconditions.
Efficientlymanagingpeoplewithcomplexandchronicconditionsisamongthegreatestchallengesphysicians,healthsystems,andpayersface.
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1K.A.Locher,R.A.Goodman,S.Posner,A.Parekh.2013.“MultipleChronicConditionsAmongMedicareBeneficiaries:State-levelVariationsinPrevalence,Utilization,andCost,2011.MedicareandMedicaidResearchReview3(3).
…thecomplexhealthconditionchallenge
H + $…arenearly1.5timesmorelikelytobere-hospitalizedwithin30days
…are4timesmorelikelytohaveanemergencyroomvisit
…cost5.5timesmoreforannualcarethanthosewithoutcomplexhealthconditions1
Peoplewithcomplexhealthchallenge:
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870644700200
0
5,000
10,000
15,000
20,000
25,000
6,900
7,100
6,400
1,100
2,4142013Total
CAGR54.9%
21,5002018Total
40.6%
55.7%
61.6%
51.3%
CAGR
CAGR
CAGR
CAGRRevenu
es(U
S$m
illion)
2013 2018
NorthAmerica Europe Asia-Pacificregion Restoftheworld
SOURCE:Mobilehealthtechnologiesandglobalmarkets,BCCResearch,2014
Improvesoutcomes
Focussesonprevention
Promotepatientindependence
MinimizesAvoidableservice
use
GlobalmHealthMarketrevenues,2013– 2018(USDmillion)
mHealth enabling remotepatientmonitoring
CAGR:CompoundAnnualGrowthRate
427 $328 266NumberofDevices AveragePrice(USD) NumberofCompanies
Proliferationofmedicalwearables- 8xgrowthinwearablemedicaldevicesby2023Markettospikefrom$4.1bnto$41.8bninnext9years
SOURCE:Vandrico
Biofourmisoverview|StrictlyConfidential|December,2017|Slide3
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AsophisticatedHIPAAcompliantpersonalizedhealthanalyticsplatformbasedonhumanphysiology.
introducingbiovitalsTM
biovitalsTM
biovitalsTM
learnsthecorrelationbetweenonesphysiologyandactivity
buildsadynamicallyvaryingpersonalizedbaseline
resultsinpersonalizedphysiologicalhealthmodel
signals/predictshealthdeterioration,healthimprovementandmedicationeffect
Data Insights Action
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howitworks
biovitalsTM
deviceagnosticplatformAPIstopulldatafromFDA/CEmarkmedical
devices
HeartRate
Weight
Spo2
BloodPressure
RespirationRate
Electrocardiogram
Activity
Sleep
artificialintelligenceCognitiveenginetolearnindividualsphysiology
datafrombio-sensors
machinelearning/predictiveanalyticsDynamicallyvaryingpersonalizedbaselinewhichindicatesandpredictspatientshealth
deterioration,improvement oranysubtlechangesduetomedication
Biovitalsisastate-of-the-artanalyticsenginethatusesadvancedmachinelearningtoprovidepredictive,preciseandactionablehealthinsights
Patienthealthdeterioration
Biovitalsindex
HeartRate
SystolicBP
RespirationRate
Activity
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Advancedsignalprocessingtoextract10+keyhealthparametersusingElectrocardiogram(ECG)andPhotoplethysmogram (PPG)
ArtificialIntelligenceenginewhichmodelstheinterplaybetweenvariousphysiologicalparameterstogenerateabiovitalsTM index
ThecardiacmoduleofbiovitalsTM unlocksthepotentialofECGandPPGbiosignalstointerpretandderivethefollowing:- Cardiacarrhythmias(AtrialFibrillation/Flutter)- QTandSTanalysis- VentricularandSupraventricularEctopy- Bradycardia- HeartRateVariability- RespirationRate/Depth- CardiacOutput&StrokeVolume- BloodPulseWave- PulseTransitTime- BloodPressurevariations- +31derivativeswhicharepredictorofcardiachealthdeterioration
BiovitalsTM indexdetectsthephysiologicaldeviationsfromonespersonalizedbaselinethatmayresultinwidearrayofhealthconditionslike:- CongestiveHeartFailure- Post-MI&Post-cardiacCatheterization- COPD- Hypertension- OSA- ChronicPainPhysiologicaldeviationsalsoindicateandmeasuretheinfluenceofmedicationonindividualsoverallhealth
iECGholtermonitorfromiHealthcombinedwithbiovitalsTMforautomatedinterpretationofelectrocardiogram
biovitalsTM featuresEnablingclinicians,researchers&pharmaceuticalstogetdeeperinsightsintoapatientwithanambulatorymonitorusing
cloud-basedHIPAAcompliantplatform
Allanalyticscaneasilybeexportedintoany3rd partyanalyticstoolsorapplicationusingourwelldocumentedAPIs
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case #1BiovitalsIndexTM
HeartRate
RespirationRate
Activity
AFBurden
Weight
BloodPressure
Patient73 yearsoldWhitemale,NYHAIII(moderate),HTN,COPD,diabetes,andCAD
A11September
DischargedaftertreatmentforpulmonaryedemaDischarged:15Sep2017
HFevent18Sep– 24Sep
WorseningHeartFailurewithelevatednight-timeRRandHR/AF.GradualincreaseinweightandBP.
A HFevent B
B1October
AdmittedwithworseningHeartFailureandchestdiscomfort.NewdiagnosisofAtrialFibrillation.Discharged:6Oct2017
Discussion:WouldthepatientbediagnosedandtreatedearlierwithBiovitalsIndexTM?
Biofourmisoverview|StrictlyConfidential|December,2017|Slide7
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beatHFTM end-to-endsolution
biovitalsTMPersonalizedpatientsinsights
beatHFTM isanend-to-endintegratedsolutionpoweredbybiovitalsTM toprovidehomemonitoringforat-riskambulatorycardiacpatientstopreventhospitalreadmissions
ClinicalgradeFDA-clearedwearablebio-sensorsforambulatorypatientmonitoring
iOS/Androidmobileapplicationforvitalsignsmonitoring,medicationmanagement,goalsetting(diet&activity),PROMsandsecureclinicalmessaging
Caregiver’splatformwithautomatedpatientriskstratificationbasedonthepredictedriskofhealthdeteriorationandin-depthinsightsintooverallphysiologyandlifestyle
BiovitalsTM analyticsenginewithreal-timephysiologicaldataprocessing
Aqualifiedteamoftrainedcardiacnursesand24/7clinicalcallcenterbeatHFTM platformcustomizedforpost-operativeambulatorymonitoringof
patientssufferingfromCongestiveHeartFailuretopreventhospitalreadmission
Patientwearablesandmobileapp Physiologicaldataprocessing 24/7cardiaccareteam MedicalPractice
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casestudy:beatHF(N=79)Projecttitle:Post-acutepatientmonitoringwithheartfailureat-hometopreventavoidablehospitalreadmission;formembersfromProfMedandKeyHealthmedicalschemeinSouthAfrica.
biovitalsTM
ContinuousphysiologymonitoringusingEverion®MDandCardioStikEKGTM alongwithpatientmobileapp
Real-timeanalysisofhumanphysiologytopredictpatienthealthdeterioration
24/7clinicalcallcenterandcardiaccareteamenabledwithclinicaldashboardwithpatientinsights Practicingphysician/provider
6monthsprogramwithcontinuousmonitoring
Reimbursementbymedicalscheme
Weeklyhomevisitsbycardiacnurseforinitial30days
Monthlysubscriptionbasedpaymentmodel
Biofourmisoverview|StrictlyConfidential|December,2017|Slide9
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casestudy:beatHF(N=79)Projecttitle:Post-acutepatientmonitoringwithheartfailureat-hometopreventavoidablehospitalreadmission;formembersfromProfMedandKeyHealthmedicalschemeinSouthAfrica.
biovitalsTM
ContinuousphysiologymonitoringusingEverion®MDandCardioStikEKGTM alongwithpatientmobileapp
Real-timeanalysisofhumanphysiologytopredictpatienthealthdeterioration
24/7clinicalcallcenterandcardiaccareteamenabledwithclinicaldashboardwithpatientinsights Practicingphysician/provider
6monthsprogramwithcontinuousmonitoring
Reimbursementbymedicalscheme
Weeklyhomevisitsbycardiacnurseforinitial30days
Monthlysubscriptionbasedpaymentmodel
Biofourmisoverview|StrictlyConfidential|December,2017|Slide9
TotalNo.ofhospitalizations(90daysmonitoringduration)
0TotalNo.ofERvisits
2TotalNo.ofinterventionbythecareteam
(90daysmonitoringduration)
100+Averagecompliancerateforphysiologymonitoring**
93%**93%compliancerateobservedforphysiologymonitoringusingwearablebiosensors:EverionMDandCardioStikEKG*Calculated at the biovitals index alert threshold of 0.4
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case #2
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A HFEvent1 HFEvent2
Patient 68yearsoldwhiteAfrikaansmale,ICM(EF=38%),NYHAIII,CABG,HTN,CKD,AF
A9Oct
Dischargedaftertreatmentfordiagnosedacutecoronarysyndrome,unstableangina&HFexacerbation.Discharged:9Oct2017
HFevent113Oct
InterventionbyCareteamMissedhismedicationFurosemide;forgottoreplenishhismedicine.
HFevent214Oct
InterventionbyCareteam:ERvisitPatientexperiencessevereSOBat-night.Outpatienttreatment/ER:Carloc25mg,Spiractin25mg,Furosemide40mg/4mlIV
B15Oct- Present
Newbaselinepost-intervention:Stablephysiology,goodmedicationcompliance,increaseinactivitylevels
B
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targetmarkets
Post-cardiaceventcare Pharmaceuticalandresearchclinicaltrials
ClinicalInstitutes,WearableandIoTmedicaldevices
EnablingpayersandproviderstoproactivelymonitortheircardiacpatientsusingbeatTM to
preventhospitalreadmissions
Leveragingcontinuousphysiological&lifestyledatacombinedwithpersonalizedanalytics(BiovitalsTM)intoclinicaltrialsandresearchtogeneratenovel,
transformationalendpoints
Enablingwearableandbio-sensormanufacturingwithBiovitalsTM APIs/SDKstoenhancetheirproductoffering
usingourreal-timeopticalandelectricalbiosignalinterpretationandpersonalizedphysiologicalengine
B2B subscription basedbusinessmodel
End-to-endserviceAnintegratedsolutionwith24/7clinicalcareteam
SoftwareasaServiceOneormoreservicesaccessedusingBiovitalsTM API
Biofourmisoverview|StrictlyConfidential|December,2017|Slide12
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