ANALYTICA -...

March 2014

Volume 27 Number 3

www.chromatographyonline.com

ANALYTICA

2014 GUIDE

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CONTENTS

5 Introduction

10 Conference Spotlight

14 Exhibitor Highlights

26 Guide to Munich

34 Staff

ANALYTICA

2014 GUIDE

4 ANALYTICA 2014 GUIDE

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www.chromatographyonline.com 5

INTRODUCTION

Analytica 2014 will open its gates for

the 24th time and Munich once again

serves as the gathering place for the

international laboratory-technology,

analysis, and biotechnology industries.

From 1–4 April 2014 the focus will be

on the latest products and innovations

in the laboratory sector, alongside a

varied educational technical programme.

More than 1100 manufacturers from

around the world will be exhibiting in five

halls to give visitors a compact market

overview. In parallel with the exposition,

the international scientific elite will meet

at the Analytica Conference organized

by the German Chemical Society

(GDCh), the Society for Biochemistry

and Molecular Biology (GBM), and

the German United Society for Clinical

Chemistry and Laboratory Medicine

(DGKL). Furthermore, visitors can expect

best practice presentations and lively

discussions in the Analytica Forums.

Here I will give a brief overview of my

personal highlights.

Live Labs and Special Shows

Modern analysis techniques and

innovative biological methods are now

indispensible in most branches of

industry — whether in the production of

medications or quality control of drinking

water. Analytica 2014 will therefore

revolve around the analysis of food and

plastics, as well as genetic analysis and

bioanalysis. These topics will be reflected

in both the trade fair and its programme

of related events, as well as the Live

Labs. Thirty-minute lectures and product

presentations are on the agenda three

times a day at 11:00, 13:00, and 15:00. In

addition to other topics, the lectures will

deal with routine analysis applications

as well as special analysis techniques.

Visitors will have the chance to exchange

ideas and information directly with

manufacturers and experts, have new

products explained to them, and discuss

specific applications.

Whether in research or industry,

employee safety is paramount. This year

Analytica integrates this topic into its Live

Labs in Hall A3 with experimental lectures

on how to avoid fires and explosions.

It will also examine the best ways to

protect employees’ health in everyday

laboratory operations and what measures

are necessary. Exhibitors will also have

the opportunity to present products that

are necessary for safety such as safety

cabinets, gas detectors, and protective

clothing. There will be demonstrations

Analytica 2014


ANALYTICA 2014 GUIDE6

INTRODUCTION

every day at 12:00 and 16:00 in German

and at 14:00 in English.

Conference

The programme of lectures at

the Analytica Conference covers

the analysis sector in its entirety,

from pharmaceutical analysis,

bioanalysis, and medical diagnostics

to environmental, water, and material

analysis. Held in conjunction with and

on the first three days of the fair, it is

being held in the immediate vicinity of

the fair, at the ICM — Internationales

Congress Centre München, for the first

time. Experts from Germany and abroad

will use the conference to talk about the

current state-of-the-art and development

prospects in analysis, biochemistry,

and clinical diagnostics. You can take

a look at the conference highlights on

page 10 in this issue. Admission to the

conference is included in the price of

admission to the fair.

Forum Laboratory and Analytics

In the Forum Laboratory and Analytics

in Hall B2, the latest products on the

laboratory and analysis market will be

presented. On the final day, the Analytica

Job Day will be held here.

Forum Biotech: Best Practice for

Users

Life scientists use increasingly refined

methods to complete the puzzle of

life more and more, even though they

often have just a few cells or microlitres

available for their analysis. As equipment

manufacturers master these and other

bioanalysis challenges, they report on

their accomplishments in the form of

Best Practice lectures and presentations

in the Forum Biotech in Hall A3. The

biotech region of Munich is considered a

leading cluster for personalized medicine

and targeted therapies. Analytica

therefore places special importance on

this topic with an additional series of

lectures as part of the forum. Lectures

and panel discussions on recent and

future developments and methods are

planned.

Analytica Finance Day

Biotechnology continues to increase in

significance as a key interdisciplinary

technology. However, the question of

reliable financing is still one of the topics

that concerns a number of companies

— one more reason to get tips from

experts at Analytica Finance Day! This

is where start-ups and established


For the best in SFC columns contact Daicel

the chiral experts at [email protected]

Working with

super-critical separations requires super-critical column performance.

Now you can get the high-quality columns you need for your most

demanding SFC separations from the worldwide leader in chiral

technology. Daicel’s new chiral columns are engineered to a new

3 mm i.d. dimension to meet the demand of high-performance SFC.

Introducing Daicel’s new SFC columns – optimised

for success in high-performance SFC systems.

• Full range of chiral SFC columns

available for the best results

• High-resolution SFC

• Available in immobilised

and coated phases

• 3 micron particle size

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INTRODUCTION

companies in the biotechnology sector

go to get valuable tips about the latest

financing trends and models. Among

other things, the latest market statistics

will be presented by Ernst & Young,

and there will be a presentation on

the topic of bio-economics involving

Dr. Viola Bronsema, who is MD of BIO

Deutschland. In addition, start-ups will

have the opportunity to make an “elevator

pitch” to present their companies and

their areas of activity. For the first time

ever, Finance Day will be on the third day

of the fair (3 Apri).

Think Tank: Analytica Promotes

New Ideas

Both start-ups and university

spin-offs give essential impetus to the

scientific and commercial sectors.

Future-oriented branches of industry

such as biotechnology and the life

sciences thrive on this dynamic. This

year Analytica features a special

presentation space for this branch of

industry known as the Innovation Area.

New technologies, products, services,

research results, and business ideas are

presented in Hall A3.

Products designated “Made in

Germany” enjoy a unique reputation

around the world. To promote the

innovative strength of German start-ups,

the Federal Ministry for Economic Affairs

and Energy (BMWi) has been promoting

their participation in the fair for years.

At Analytica, start-ups have a chance

to participate in one of two “Made in

Germany” joint exhibits in Halls A3 and

B2 at affordable rates and present their

own technologies to an audience of

international professionals.

I’m looking forward to seeing you in

Munich.

Susanne Grödl

Exhibition Director analytica


Thinking Forward.

Contact us: Phone + 49 6131 962390 www.pss-polymer.com [email protected]

The whole is more than the sum of its parts – the value of 2 dimensions by PSS.

True Molar Masses

Composition

Comonomer distribution

End groups

2-dimensional chromatography gives you more

answers – by doubling the power of the analysis you

quadruple the amount of information and resolution.

The PSS 2D Polymer Analyzer with WinGPC

UniChrom Software combines separation techniques

such as HPLC and GPC/SEC in an automated,

easy-to-use and user-friendly solution.

Find out what your samples really contain!

Hall 1 Booth 424


CONFERENCE SPOTLIGHT

Time Tuesday

11:00 • Difficulties and Solutions in the Analysis of Polar

Compounds by LC–MS: Examples from Research

and Routine Analysis (ICM, Hall 3)

• Quantitative Molecular Imaging of Neurotransmitters

Directly in Histological Tissue Sections (ICM, Hall 2)

11:30 • Identifying Sources Contributing to Poor Air Quality

Using Aerosol MS Techniques (ICM, Hall 5)

• From Target to Non-Target Screening: Comprehensive

Characterization of the Aquatic Environment Using

LC–HRMS–MS (ICM, Hall 3)

12:00 • MALDI Molecular Imaging of Proteins, Metabolites,

and Drugs for Preclinical and Clinical Research

(ICM, Hall 2)

• Microchambers and Microdroplets: New Perspectives

for Proteomics and Single-Cell Analysis (ICM, Hall 4a)

12:30 • The Challenge of Identification and Quantification

Transformations Products in the Water Cycle (ICM, Hall 3)

• Pathogen Analysis on Chip: Sample Enrichment,

Preparation, and Detection (ICM, Hall 4a)

13:00 • Identification of New Transformation Products of

Selected Antibiotics formed during Advanced

Oxidation, Photolysis, and Enzymatic Wastewater

Treatment Processes by On-Line Turbulent Flow

LC–LTQ–Orbitrap–MS (ICM, Hall 3)

14:00 • The Evolving Frontiers of Analytical Chemistry

(ICM, Hall 3)

• Metabolomics Should Pay Great Attention to

Standard Operating Procedures (ICM, Hall 2)





Wednesday Thursday

• Electrochemistry/Mass Spectrometry as a • Trace Elements: Challenges for the

Tool for Phamaceutical (ICM, Hall 3) Analyses of Bulk Concentrations

• Systems and Synthetic Biology of and Species (ICM, Hall 5)

Mammalian Circadian Clocks • Scalable, Multiplexed, and Sensitive

(ICM, Hall 4a) Immunoassays (ICM, Hall 2)

• Towards a LC–MS–MS Based Clinical- • Application of Nanoparticles in POCT

Chemical Analyzer for Small Molecules (Point-of-Care Testing) (ICM, Hall 3)

(ICM, Hall 3)

• Chemometrics – How to Get More Information • Immuno-MALDI Mass Spectrometry for

out of Complex Data (ICM, Hall 5) Clinical Proteomics (ICM, Hall 2)

• Single Molecule Fluorescence Spectroscopy • Elemental Bioimaging in Pharmaceutical

and its Potential for Analytical Chemistry Analysis (ICM, Hall 5)

(ICM, Hall 5) • Chemometric Processing of Chemical

Fingerprints (ICM, Hall 4a)

• Nanoscale Sensing Devices for Label-Free • Clinical Proteomics for Sickness and

On-Chip (bio) Chemical Analysis Wellness (ICM, Hall 2)

(ICM, Hall 5) • Enhancing Performance of Sensors by

• Towards HYPERformance Comprehensive Nanomaterials (ICM, Hall 3)

Two-Dimensional Liquid Chromatography

(ICM, Hall 3)

• Microfluidic Manipulations: Confining • Data Fusion: The Art of Harvesting

Living Organisms in Small Volumes Synergy from Complementary Analytical

(ICM, Hall 5) Data (ICM, Hall 4a)

• DNA-Based Food Authenticity Control

(ICM, Hall 3)

• Chiral Method Development: Parallel • Assessing Chemodiversity of Different

Screening and SFC Systems (ICM, Hall 3) Wine with Metabolomics (ICM, Hall 3)

• Drug Testing in Dried Blood Spots • MRM from Dried Blood Spots to

(ICM, Hall 5) Quantify Multiple Proteins for Clinical Use

(ICM, Hall 4a)





Time Tuesday

14:30 • Analyzing Thousands of Individual Cellular Lipid

Species Without HPLC Separation (ICM, Hall 2)

• Quantification of Health-Relevant Aerosol Components:

Development of Novel Analytical Techniques

(ICM, Hall 5)

15:00 • Ionic Liquids in Separations and Mass Spectrometry

(ICM, Hall 3)

• Purification and Preconcentration of Mycotoxins and

its Metabolites by Molecularly Imprinted Adsorbents

for Biomedical Analysis (ICM, Hall 2)

15:30 BREAK

16:00 • The Need of Integrating Multiple Analytical

Dimensions in Metabolomics (ICM, Hall 2)

• Hydrodynamic Focusing for Biosensors and

Biomaterials Fabrication (ICM, Hall 3)

16:30 • Nano- and Quantum-Biodevices for Cancer

Diagnosis, Cancer Therapy, and iPS Cell Based

Regenerative Medicine (ICM, Hall 3)

17:00 • Effects of Complex Mixtures of Chemicals: Emphasis

on Extracts from Diesel Exhaust Particles (ICM, Hall 5)

• Driving Biological Discovery Using Mass

Spectrometry (ICM, Hall 3)





Wednesday Thursday

• Miniaturized Multiplexed Imunoassays for • Lipids and Ecdysteroids in Developing

Biomarker Discovery (ICM, Hall 2) Drosophila (ICM, Hall 2)

• Drug Testing in Exhaled Breath • Food Fingerprinting: Employing High

(ICM, Hall 5) Resolution MS (ICM, Hall 3)

• Heart-Cut and Comprehensive 2D-LC • Utilizing the Novel LipidBlast Virtual

Separation Applied to Complex Sample MS–MS Library in High Throughput

Chemistries (ICM, Hall 3) Blood Plasma Screening of Clinical

Cohorts (ICM, Hall 2)

BREAK BREAK

• Multiplexed MRM Quantitation for Protein • Development and Application of an Exact

Biomarker Verification of Human Plasma Mass LC–MS–MS Library for the Screening

and CSF (ICM, Hall 2) of Mycotoxins in Food (ICM, Hall 3)

• Unravelling the Mystery of Wine Aroma:

Beneficial Use of Multidimensional GC

Systems (ICM, Hall 3)

• Drug Metabolism by Wastewater Microbes • Bridging the Biological and Analytical

(ICM, Hall 5) Sciences to Determine the Role of

• Systematic Characterization of Human Aberrant Lipid Metabolism in the Onset

Platelets in Arterial Vascular Disorders by and Progression of Disease (ICM, Hall 2)

Quantitative Proteomics (ICM, Hall 2)

• Analytical Challenges and Solutions in • High Throughput Quantification and

Pharmaceutical Discovery Metabolic Profiling of Lipid Species

(ICM, Hall 3) (ICM, Hall 2)




EXHIBITOR HIGHLIGHTS

When measurement matters, Agilent Technologies can offer

tools and solutions for scientists, researchers, manufacturers,

and businesses, as well as government agencies. From food

safety to material science, from pharmaceutical analysis to

discovering the genetic basis of disease, Agilent instruments

can provide the measurement capabilities that make the world a

more productive and a safer, healthier, more enjoyable place to

live. Visit the Agilent booth at 105–106 (Hall A2) to discover the

company’s recent product developments and ever-expanding

solutions.

AGILENT TECHNOLOGIES

www.agilent.com

[email protected]

A2.105

At Analytica 2014, AkzoNobel will showcase Kromasil

EternityXT UHPLC and HPLC columns based on

state-of-the-art grafting technology, used for reversed-phase

separations and purif cations that require harsh conditions,

fast turnaround, easy method transfer, and seamless scale-up

from R&D to production. The company report that its Kromasil

brand is a premium choice for separations and purif cations

and is available for a wide range of NP, RP, SFC, and chiral

applications.

AKZONOBEL

www.kromasil.com

[email protected]

A1.240

Avantor Performance Materials manufactures and markets

high performance chemistries and materials around the

world. Avantor is an established global supplier of high-purity

laboratory chemicals, including solvents, acids, solutions,

salts, minerals, and sugars. Avantor products are used in

research and production laboratories, environmental testing,

industrial manufacturing, and many other areas around the

world, delivering the quality and purity needed for demanding

applications.

AVANTOR PERFORMANCE MATERIALS

www.avantormaterials.com

[email protected]

A1.215


Research-Grade Technology Meets High Productivity

LC-MS/MSInnovation with Integrity

The compact mass spectrometer delivers full sensitivity resolution so there is

no need to choose between resolution and sensitivity. One shot plug and play

acquisition ensures qualitative and quantitative results in one LC run with the

fastest time-to-results. And finally, enhanced dynamic range during real LC time

scales reduces sample preparation, key in high-throughput quantitative applications.

Don‘t accept compromise, choose the compact mass spectrometer.

www.bruker.com

Visit us at Analytica 2014, Hall A2, Booth 329




Berthold Technologies, a worldwide supplier of radio isotope

detectors for liquid chromatography applications, has

manufactured f ow monitors in Germany for more than 35 years.

The current portfolio consists of the FlowStar, a multi-purpose

detector operated in coincidence mode with exchangeable

measuring cells for various f ow rates, isotopes, activities, and

pressures including UHPLC applications. All instruments can

be operated with the RadioStar software or can connect to the

HPLC system software via digital or analogue outputs.

BERTHOLD TECHNOLOGIES

www.Berthold.com/bio

[email protected]

B1.417

For over three decades, Biosolve has produced high purity

solvents, reagents, and targeted chemical compounds for

the pharmaceutical industries and biotechnology. Bio-lab and

Biosolve Chimie have the highest ISO standards by using

stringent quality control processes. Excellent service starts

with the right packaging through to swift and reliable delivery.

Biosolve welcomes you to contact them whenever you need

sound advice for product design that accommodates your needs

the best.

BIOSOLVE CHEMICALS

www.biosolve-chemicals.eu

[email protected]

B1.114

Biotage is a global company active in life science technology.

With a broad scope of tools for synthesis, work-up, purif cation,

evaporation, and analysis, the company offers solutions,

knowledge, and expertise in the areas of analytical

chemistry, medicinal chemistry, peptide chemistry, and

process-development. Products featured at Analytica 2014

will include the Biotage Extrahera SLE and SPE automation

system, the Isolera Dalton mass directed f ash chromatography

system, and the Initiator+ Alstra automated microwave peptide

synthesizer.

BIOTAGE

www.biotage.com

[email protected]

A1.221




Chiral Technologies, a global leader in enantioselective

chromatography, serves the pharmaceutical and other life

science industries and offers a large portfolio of chiral stationary

phases (CSPs) and analytical and preparative chiral columns

for the separation of racemic mixtures into single enantiomers.

The company also provides analytical method development

and custom separation services. On show at Analytica 2014 will

be the Chiralpak IE and IF, the newest addition to the Chiral

Technologies family of immobilized CSP.

CHIRAL TECHNOLOGIES

www.chiral.fr.

[email protected]

A1.229A

CHROMacademy offers instruction for analytical chemists

via www.CHROMacademy.com, an intuitive e-learning and

troubleshooting website with more than 5,000 pages of content

for HPLC, GC, sample preparation, hyphenated techniques,

and IR. Also available are “Essential Guide Webcasts” and

Tutorials, as well as live tutor led training events such as “Live

On The Web” and “Live @ Your Place”. No other educational

platform offers separation scientists more live streaming events,

a comprehensive knowledge base, practical solutions and new

technologies in one easy to navigate website.

CHROMACADEMY

www.CHROMacademy.com

[email protected]

B2.148

CTC Analytics AG is a leader in front-end automation for gas

and liquid chromatography. Visit the booth to see the PAL RTC

instrument, which is said to remove bottlenecks in laboratory

workf ows in seconds. The RTC changes automatically between

different syringes, liquid injection, headspace, and solid-phase

microextraction (SPME) without the need for manual

intervention. A new addition is the PAL RSI. Optional for both

systems are a vortex mixer, incubator, temperature controlled

storage, and a complete range of valves and syringes (1 μL to

10 mL).

CTC ANALYTICS AG

www.palsystem.com

[email protected]

A1.337




DataApex will be exhibiting Clarity software at Analytica

2014. Able to control over 450 different instruments from one

environment, the software is multilingual, with the option to

switch between English, Chinese, Russian, Spanish, French,

and German. The new MS extension allows for data acquisition

from MS detectors and simultaneous data evaluation for both

conventional and MS detectors. The company report that it is

easy to operate, and includes free SW updates and optional

extensions (including PDA, GPC, and NGA). A free demo

version is available from the website.

DATAAPEX

www.dataapex.com

[email protected]

A1.500

Fortis Technologies supplies UHPLC and HPLC columns

to the pharmaceutical, environmental, and food industries.

Utilizing silica and bonding technologies at its UK site, Fortis

Technologies aims to supply innovative solutions to the

separation and purif cation industries. This year is the launch of

the company’s core–shell particle, Fortis SpeedCore, designed

to enhance speed, sensitivity, and resolution of analysis. The

particle is available in several phase chemistries to match the

need of the individual analyst. Fortis also manufactures 1.7 μm

particles specif cally for use in UHPLC.

FORTIS TECHNOLOGIES

www.fortis-technologies.com

[email protected]

A2.132

GE Healthcare Life Sciences offers tools for drug discovery

research, upstream and downstream biopharmaceutical

manufacturing, and cellular technologies. The company has

broad expertise across the life sciences, and is committed to

helping researchers around the world discover new and effective

ways to predict, diagnose, and treat disease. Products featured

at Analytica 2014 will include ÄKTA pure 150, Cytell Cell Imaging

System, Amersham Imager 600, and bioreactors such as the

ReadyToProcess WAVE 25.

GE HEALTHCARE LIFE SCIENCES

www.gelifesciences.com

[email protected]

A3.306




Gerstel develops and produces automated solutions for

GC–MS and LC–MS including sample preparation and sample

introduction. At Analytica 2014, Gerstel will showcase the

MultiPurpose Sampler for automating derivatization and addition

of standards. Sample clean-up techniques include SPE; on-line

SPE with exchangeable cartridges; f ltration; centrifugation; and

vortexing. Solvent-free extraction and concentration techniques

for GC–MS include: Headspace, dynamic headspace (DHS),

thermal desorption, thermal extraction in µ-vials, SPME, and

SBSE — all operated with MAESTRO PrepAhead efficiency.

GERSTEL

www.gerstel.com

[email protected]

A1.323

Hamilton is a global company specializing in the design and

manufacture of liquid handling, process analytics, robotics, and

automated storage solutions. For more than 60 years, Hamilton

has combined quality materials with skilled workmanship

to ensure the highest level of performance. Founded on the

technology of analytical microlitre and gastight syringes,

Hamilton has a wide offering of laboratory products including

Arc pH, DO and conductivity intelligent sensors, Microlab 600

Diluters and Dispensers and the Microlab 300 Guided Pipetting

System.

HAMILTON

www.hamiltoncompany.com

[email protected]

B1.304

Idex Health and Science is a leading company in f uidic

products and components for life science instruments and

laboratory applications. They offer a broad product portfolio that

includes valves, f ttings, tubing, column hardware, precision

dispense pumps, degassing, detection technologies, manifolds,

and peristaltic pumps.

IDEX HEALTH AND SCIENCE

www.idex-hs.com/analytica

[email protected]

A2.425




Labomatic Instruments offers standard and customized

solutions for preparative HPLC, preparative liquid handling

systems, and a wide range of tubings, assembled tubings,

f ttings, and other products for analytical, medical, and f uid

handling systems. Products on show at Analytica 2014 will

include the HD-5000 triple-piston gradient pump, with an

integrated system controller for preparative HPLC, and the

HD-5000 for low pressure gradients.

LABOMATIC INSTRUMENTS

www.labomatic.com

[email protected]

A1.134

LC•GC will be showcasing its three print publications, LC•GC

North America, LC•GC Europe, and LC•GC Asia Pacifi c at

Analytica 2014. LC•GC’s fortnightly digital e-zine, The Column,

will also feature. Working alongside CHROMacademy, the

magazines offer separation solutions to scientists working

in a range of industries by providing peer-reviewed articles,

troubleshooting information, market analyses, and much more.

Please feel free to call at the LC•GC booth to discuss any

queries or upcoming editorial, sales or marketing

opportunities.

LC•GC


[email protected]

B2.148

LECO Corporation offers a range of analytical equipment

including CHNOS elemental analyzers for organic and inorganic

materials, thermogravimetry, calorimeters, GDS spectrometers,

metallographic solutions, and consumables. The separation

science division offers comprehensive chromatography and

time-of-f ight mass spectrometers. Customers around the

world have trusted LECO to provide analytical solutions for

a variety of applications and markets. LECO can provide the

right combination of instruments to meet your needs, and

professional service and application support.

LECO CORPORATION

www.leco-europe.com

[email protected]

A1.324




Malvern Instruments offers materials and biophysical

characterization systems that can be used across a diverse

range of industries and applications. On show at Analytica 2014

will be the Viscotek SEC-MALS 20, an addition to Malvern’s

range of GPC/SEC detectors. The detector measures absolute

molecular weight of proteins and all types of natural and

synthetic polymers. It also measures radius of gyration (Rg)

for molecules over 10 nm. Malvern report that the system’s

20 angles and low angles improve data quality giving more

accurate molecular weight and Rg measurements.

MALVERN INSTRUMENTS

www.malvern.com

[email protected]

A1.227

Markes International, an industry leader in technology for trace

organic analysis, manufactures a range of instrumentation and

software that enhances the analytical capability of GC–MS. As

well as having a reputation for thermal desorption solutions for

GC, Markes also manufactures the BenchTOF time-of-f ight

mass spectrometers — powerful tools for GC or GC×GC

analysis of targets and unknowns. New for Analytica 2014 will

be Select-eV, a variable-energy electron ionization technology

for GC–MS.

MARKES INTERNATIONAL

www.markes.com

[email protected]

B2.138 & B2.145

Metrohm specializes in titration and voltammetry and in the

manufacture of instrumentation for ion chromatography,

process analysis, laboratory instrumentation, and near-infrared

spectroscopy. At Analytica 2014, the 940 Professional IC Vario

high-performance ion chromatography system for research

applications and routine use will be on show. Entirely modular

by design, Metrohm report that the system enables unlimited

conf guration possibilities and meets even the most challenging

analytical requirements.

METROHM

www.metrohm.com

[email protected]

A1.101




Founded in 1981, the Molnár-Institute focuses on strategies

for improving the efficiency and success of modern (U)HPLC.

With its comprehensive resolution and robustness mapping

abilities, DryLab offers an intuitive and visual software solution

for method development, optimization, trouble-shooting,

robustness testing, and training. The latest product from

the Molnár-Institute, the Knowledge Management Reporting

Tool, is reported to help scientists create QbD-conforming

method reports ready for submission to regulatory authorities,

signif cantly speeding up the process of regulatory approval.

MOLNÁR-INSTITUTE

www.molnar-institute.com

[email protected]

A1.534

Considering changing from helium to hydrogen carrier gas for

your GC? Parker Hannif n has an extensive range of ultra-high

purity hydrogen generators, reportedly ideal for carrier gas,

including the new PEM Palladium range — 99.99999%

purity, 11.9 bar and 1300 mL/min. Parker is a leading provider

of hydrogen, nitrogen, and air generators for the analytical

instrument market. Generators are specif cally designed to meet

the stringent gas requirements of the leading manufacturers of

GC, GC–MS, LC–MS, and many more analytical instruments.

PARKER HANNIFIN

www.parker.com/dhfns

[email protected]

A1.519

Peak Scientif c Instruments Ltd is a manufacturer of laboratory

gas generators including nitrogen, hydrogen, and zero air,

reported to be suitable to operate most laboratory analytical

applications such as LC–MS and GC. At Analytica 2014 Peak

Scientif c will be exhibiting the Precision Series. A modular

gas generator range for single and multiple GC applications, it

reportedly allows the separation and analysis of multiple gas

types and complex mixtures with excellent accuracy in the most

spatially economic labs.

PEAK SCIENTIFIC INSTRUMENTS

www.peakscientif c.com

marketing@peakscientif c.com

B1.129




PSS is a specialist in the analysis of macromolecules and

provides services and supplies for GPC/SEC or HPLC of

polymers, biopolymers, and proteins. Showcased at Analytica

2014 will be the 2D Polymer Analyzer, reported by PSS to

combine separation techniques in an automated, easy-to-use,

and user-friendly solution. Data evaluation includes creation

of contour plots with just a single mouse-click. Other featured

products are the latest version of WinGPC UniChrom software,

PolarSil and NOVEMA Max columns for advanced polycation

analysis, and European reference materials.

POLYMER STANDARDS SERVICE (PSS)

www.pss-polymer.com

[email protected]

A1.424

SGE Analytical Science is a leader in creating components

and consumables used in scientif c analysis. At Analytica 2014,

a range of liquid handling, GC, and HPLC products will be on

show with the authorized distributor IVA Analysentechnik e. K.

Specializing in the f eld of scientif c glass engineering for liquid

handling and separation science, SGE has a well-established

foundation in materials science, precision glass engineering,

chemistry, and an understanding of analytical science

application. SGE is part of the Trajan Scientif c and Medical

group of companies. Learn more at www.trajanscimed.com

SGE ANALYTICAL SCIENCE

www.sge.com

[email protected]

A1.440

Polymer Char is a company dedicated to the development of

innovative and user-focused solutions for polymer analysis,

specif cally the structural characterization of polyolef ns. Featured

techniques are: Molar mass distribution using GPC/SEC (GPC–

IR, GPC One), chemical composition distribution (CRYSTAF,

TREF, CEF), bivariate distribution by cross-fractionation

chromatography (CFC), high temperature HPLC (TGIC, SGIC

2D), soluble fraction analysis or “xylene solubles” (CRYSTEX,

CRYSTEX QC), preparative fractionation (PREP mc2,

PREP C20), and infrared detection (IR4, IR5 MCT).

POLYMER CHAR

[email protected]

www.polymerchar.com

A2.224




Thermo Fisher Scientif c will be displaying LC–MS and isotope ratio

instruments, innovations in separations, and software at Analytica

2014. Products on display will include: The Thermo Scientif c

Orbitrap Fusion Tribrid LC–MS combining three mass analyzers;

the TSQ Quantiva LC–MS–MS that breaks the attogram sensitivity

barrier; and the Trace 1300 Series GC, which offers options to

conserve helium, employ multiple detectors simultaneously, and

automate sampling gas workf ows. Also featured is the Virtuoso Vial

Identif cation System, reported by Thermo to automate vial labelling

to minimize errors and increase productivity.

THERMO FISHER SCIENTIFIC

www.thermoscientif c.com

martine.ruprecht@

thermof sher.com

B1.101

Tosoh Bioscience is a leading provider of liquid chromatography

technology. The company’s portfolio encompasses GPC

instruments and a comprehensive line of biopurif cation

media and (U)HPLC columns for all common modes of liquid

chromatography. At Analytica 2014 Tosoh Bioscience will

showcase products for HPLC bioanalysis, biopurif cation, and

SEC/GPC analysis, such as the TSKgel SuperSW mAb series

of SEC columns for antibody analysis, the ultra-high capacity

TOYOPEARL Protein A and mixed-mode media, and the high

temperature GPC system EcoSEC HT.

TOSOH BIOSCIENCE

www.tosohbioscience.de

[email protected]

A2.223

Shimadzu is one of the world’s leading manufacturers of

analytical instrumentation. The company’s equipment and

systems are used as essential tools for quality control in

health, environmental, and consumer protection. Business

segments of chromatography, spectroscopy, environmental

analysis, balances, biotechnology, and material testing make

up a homogeneous yet versatile offering. At Analytica 2014,

Shimadzu will exhibit the new LCMS-8050 triple quadruple

LC–MS–MS system that meets the growing demand for

trace-level quantitation in clinical research and other markets.

SHIMADZU

www.shimadzu.de

[email protected]

A1.502




YMC Europe offers a wide range of products for

chromatographers including (U)HPLC columns, bulk media for

preparative chromatography, and glass columns for MPLC and

DAC-columns. Featured products are YMC-Triart hybrid columns

with temperature and pH stability for method development. New

additions to the YMC CHIRAL-family include YMC CHIRAL

Amylose-C and YMC CHIRAL Cellulose-C available in 5 µm

analytical and preparative HPLC columns and as preparative

bulk media with 10 µm and 20 µm.

YMC EUROPE

www.ymc.de

[email protected]

A1.508

Wyatt is a world leader in light-scattering instrumentation

and software for determining the absolute molar mass, size,

charge, and interactions of macromolecules and nanoparticles

in solution. The company offers instruments for: In line multi

angle static light scattering (SEC–MALS), f eld-f ow fractionation

(FFF–MALS), composition gradients for interaction analysis

(CG–MALS), high-throughput dynamic light scattering (DLS),

high-sensitivity electrophoretic mobility (MP–PALS), differential

refractometry, and differential viscosity.

WYATT TECHNOLOGY

www.wyatt.com

[email protected]

A1.322

Waters Corporation provides a connected portfolio of

separations and analytical science, mass spectrometry, and

laboratory informatics, as well as thermal analysis products.The

following products will be displayed at Analytica 2014: ACQUITY

UPC2 System, ACQUITY QDa Detector, novel microscale

technology, PATROL UPLC Laboratory Analyzer, ACQUITY

UPLC H-Class with QDa System for Method Development,

ACQUITY APC System, analytical standards and reagents,

certif ed materials, columns and sample prep products.

WATERS CORPORATION

www.waters.com

[email protected]

A1.336



GUIDE TO MUNICH

The capital city of Bavaria has

a wealth of sights and activities

to enjoy. Situated near the foot

of the German Alps, the “music

metropolis” of Munich boasts

numerous museums and beer

gardens, as well as world-class

shopping. In this short guide,

LC•GC Europe presents a glimpse

of what’s on offer in this vibrant city.

PLACES TO EAT AND DRINK

Augustiner-Keller

Arnulfstrasse 52

Tel: +49 89 5943 93

www.augustinerkeller.de/english

This famous beer cellar is steeped in

history, being described as Munich’s

beer warehouse from 1812, its history

as a brewery can be traced back to the

17th century. There are several different

rooms offering a different ambiance,

a beer snuggery (Bierstüberl) gives

visitors a cosy feeling while the Hunting

Parlour is a much larger space often

used for business dinners or parties.

In addition to these there is a beer hall

and visitors can also take advantage

of the stocks cellar (open Mon–Sat

from 16:00–01:00); with space for

300 guests these two tubes give

an indication of how the space was

traditionally used. Of course, this

establishment features one of the city’s

oldest beer gardens, which is housed

under chestnut trees.

Al Torchio Trattoria Vinoteca

Amalienstrasse 42

Tel: +49 89 2850 49

www.al-torchio.de

Highly rated on Trip Advisor, this cosy

trattoria is located in Munich’s university

The LC•GC Guide to Munich



GUIDE TO MUNICH

district, offering traditional Italian cuisine,

produced with fresh ingredients and at

reasonable prices. If you are looking for

something a bit different to the widely

found German cuisine this is the place

to go.

Bogenhaeuser Hof

Ismaninger Str. 85

Tel: +49 89 9855 86

www.bogenhauser-hof.de

A modern and elegant, yet comfortable

restaurant ideal for business meetings

and professional gatherings. The

menu is focused on a diverse range

of international cuisine. Diners have

the opportunity to enjoy the outside

landscaped garden, the main dining hall,

or a choice of a range of smaller

rooms for private parties.

Broeding

Schulstrasse 9

Tel: +49 89 1642 38

www.broeding.de/en

This restaurant promises

innovative German

cuisine, cooked with fresh

products. The setting is

a little more formal than

some restaurants featured, with a

set menu of 5 or 6 courses available

each day. There is a wide choice of

Austrian wines available too, as the

team behind the business have been

importing Austrian wines since 1990.

It’s also a good place to go if you are

looking for conversation, as it is a

music-free restaurant. Rated as a top

restaurant, booking is advisable.

Geisels Werneckhof

Werneckstrasse 11

Tel: +49 68 8938 8795

www.geisels-werneckhof.de

This michelin star restaurant is home to

renowned chef Tohru Nakamura. The

restaurant offers refined international

cuisine with Asian influences. Customers



GUIDE TO MUNICH

can choose between a multi-faceted

Gaudi menu of five courses, or a more

refined Soli classic menu. A great place

to go if you are looking for a special

evening.

Jasmin Asia Cuisine

Munich Lindwurmstraße 167

Tel: +49 089 767757 12

www.jasmin-asia-cuisine.de/

Set back from the main tourist areas,

this is a small family-run establishment

offering specially selected

delicacies from Vietnam. It is a small

establishment, ideal for a quick snack or

light dinner. Be aware, credit cards are

not accepted.

Hofbräuhaus

Am Platzl 9

Tel: +49 (0)89 290136 10

www.hofbraeuhaus.de/en/index_

en.html

The Hofbräuhaus is considered to be

a top tourist attraction of Munich where

beer in litre-sized steins is served by

traditionally dressed people. Customers

can enjoy some German specialities

while being entertained by live “oom-pah”

music, which is performed daily on a

stage in the centre of the public beer

hall. Patrons of the bar can also enjoy a

relaxing sit in the walled beer garden.

Prinz Myshkin

Hackenstraße 2,

Tel. +49 89 2655 96

www.prinzmyshkin.com

This restaurant offers vegetarian cuisine

from all over the world. Although

slightly more pricey than some of the

beer cellars, it does have a philosophy

of only serving top-quality food that

contains no preservatives or artificial

flavours. Here you can enjoy a range

of dishes, from simple appetizers to

oven-baked meals and Asian-styled

plates to the cakes made at the

restaurant’s own patisserie. There are

also menu options available that do not

contain any dairy or egg products.

Lowenbräukeller

Nymphenburgerstrasse 2

+49 89 54 72 66 90

www.loewenbraeukeller.com/en/

Located near to the central railway

station, Löwenbräukeller is the restaurant

and beer garden annex to the massive

Löwenbräu Brewery. It opened its doors

in 1883 with more than 8000 seats and

houses a large restaurant and a casual



GUIDE TO MUNICH

“Pils-Bar” that is a spot to

see and be seen. The size of

the building is matched by

the size of the food portions,

so be prepared! A must-visit

while in Munich!

PLACES TO VISIT

Nymphenburg Palace

Eingang 19

Tel: +49 89 1790 80

www.schloss-

nymphenburg.de/index.

htm

Nymphenburg Palace was originally

designed as the summer residence

of Bavarian Elector Ferdinand Maria’s

wife Henriette Adelaide of Savoy who

was pregnant with the son and heir to

the throne, Max Emanuel. Initially the

building was a cubic pavilion situated

outside of Munich in the countryside,

but the size of the palace has increased

dramatically over the course of 200

years. Housed within the rococo

and baroque-styled palace is the

magnificent hall, the Steinerner Saal,

which was created by Johann Baptist

Zimmermann and François Cuvilliés the

Elder and spans over two floors and is

opulently decorated. The Amalienburg

hunting lodge is another of the

impressive and lavish rooms created by

François Cuvilliés the Elder; this is the

only lodge of the palace that is opened

in the winter. Guided tours aren’t usually

offered but you can purchase an

audio-guide that is available in German,

English, Italian, Spanish, and Russian.

Frauenkirche — Cathedral Church

of Our Lady

Frauenplatz 1

www.muenchner-dom.de

The Metropolitan Church of the

Archbishop of Munich-Freising is

a landmark of the city. Dominating



GUIDE TO MUNICH

the skyline, it is easy to find and

offers an impressive gothic entrance

from the 15th century. The original

architect, Jörg von Halspach, is

reported to have dropped dead after

laying the last brick and is buried

on site. It was seriously damaged

by Allied bombings, which left the

skeleton structure and little else intact.

However, it was drastically restored in

several stages from 1947, finally being

completed in 1994.

As an interesting side note, there is

a large footprint on the stone floor as

you enter the building, which is said to

be the Devil’s (the Teufelstritt). There

are two versions of the story, one

states that the Devil was ridiculing the

windowless building and stomped his

foot with glee. The other version claims

that the Devil challenged von Halspach

to make a nave that had no windows,

which he accepted. Once the job had

been completed the architect led the

devil to the one spot in the building

where you could not see the 66-foot

high windows (hidden behind pillars)

and the Devil, angered that he had

been tricked, stomped his foot in rage

leaving his footprint behind!

Tierpark Hellabrunn — Hellabrunn

Zoo

Tierparkstr. 30

Tel: +49 89 6250 80

www.tierpark-hellabrunn.de

The Hellabrunn zoo was founded in

1911 and is said to be the world’s

first geo-zoo, which means that

the animals live according to their

geographical distribution. It was shut

in 1922 but was re-opened under

the management of Heinz Heck, who

wanted to show the animals in more

open grounds rather than separated

into their zoological taxonomy. Heck

made a name for himself by successful

breeding programmes at Hellabrunn

and also, with the help of his brother,

the breeding back of extinct species

such as aurochs and tarpan. After

WWII, the zoo had to start up again for

a third time. The site now houses large

indoor enclosures and a centre for

animal welfare, nature conservation,

and the protection of species that

was built in 2007 to inform visitors of

the worldwide activities of the zoo.

Opening hours for the zoo: Oct.–Mar.

09:00–17:00, Apr.–Sep. 09:00–18:00.

Admissions for adults is €12 and

for children (4–14 years) €5 other



GUIDE TO MUNICH

concessions are available but valid ID

is required.

Neues Rathaus — the new Town

Hall

Marienplatz 8

Built from 1867 to 1909 in a

Flanders Gothic style, this building

features a striking 300-foot long

façade embellished with elaborate

ornamentation. Its tower is home to the

carillon (Glockenspiel) that demonstrates

parts of Munich’s history. The upper

tier of the clock shows figures jousting,

which represents the joust arranged

for the marriage of Duke Wilheim V

and Renata of Lothringen. The lower

level features figures performing the

“Schäfflertanz”, a traditional dance of

Munich. Visitors can enjoy the clock’s

display everyday at 11:00 and then again

at 12:00, between March and October

the clock also chimes at 17:00.

MUSEUMS AND GALLERIES

Bayerisches National Museum

Prinzregentenstr. 3

Tel: +49 89 2112 40 1

www.bayerisches-nationalmuseum.

de/Engl/b.htm

The Baviarian National Museum is

regarded as one of Europe’s major

art and cultural museums. It focuses

mainly on the artefacts from Southern

Germany and in particular Bavaria. It is

composed of three stories and houses

furniture, pottery, cribs, sculptures,

musical instruments, and much more

ranging from the Middle Ages to the

Rococo and Renaissance periods.

Adults tickets are €5 and €1 on a

Sunday (it is free for people under 18),

however entrance prices do not apply

for special exhibitions. Opening hours

are from Tuesday to Sunday

10:00–17:00 and on Thursday it has

extended hours until 20:00.

Deutsches Museum

Museumsinsel 1

Tel: +49 89 2179-1

www.deutsches-museum.de/en/

information/

The Deutsches Museum houses 50

exhibition sections covering a vast

selection of subjects from aeronautics

to textile technology. Tours and

demonstrations for individuals or families

are in German only and are free of

charge except for the Planetarium and

the general tour. Specialist tours are



GUIDE TO MUNICH

available in other languages and you

can take a general tour for €3, covering

several exhibitions and lasting about

2.5 h. There are interactive elements to

some of the exhibits, but as there are so

many things to see it is advisable to get

there early. Admission is €8.50 for adults

and €3 for children between the ages

of 6 and 15 years. It is open daily from

09:00–17:00.

Bier and Oktoberfest Museum

Sterneckerstr. 2

Tel: +49 89 2423 16 07

www.bier-und-oktoberfestmuseum.

de/english/dahoam.html

This museum is housed within a

14th-century building that has been

sensitively restored and several ceiling

paintings have been uncovered that

date back to 1340. The history of the

building is only one of the delights on

offer here, however, the rest is based on

taste. Visitors can learn about the history

of beer with the culinary-guided tour

that includes beer sampling and at the

end of the tour an enjoyable meal. There

are also beer tasting and beer brewing

courses available, and the museum bar

and restaurant that seats up to 120 is

ideal for parties. The museum is open

Tuesday to Saturday from 13:00–18:00

and the restaurant is open from 18:00–

24:00. Tickets cost €4 for an adult.

SHOPPING

Viktualienmarkt

The Viktualienmarkt is a bustling,

colourful food market at the end of the

pedestrian zone off the Marienplatz. It

has existed on the site since 1807 and

is one of the city’s major attractions. At

the heart of the market is a traditional

maypole surrounded by a beer garden.

It is an excellent place to find fresh fruits,

vegetables, cheeses, and sausages.

Stalls are generally open between 10:00

and 18:00 Monday to Friday and 10:00

until 15:00 on Saturday, however, these

times may vary from stall to stall.

Kaufingerstr./Neuhauserstr.

www.shops-muenchen.de

This pedestrian-only area starting at

Karlsplatz and ending in Marienplatz is

where you will find the familiar high street

stores as well as a few smaller boutiques.

You can find plenty of clothes shops,

jewellers, and perfumeries and there are

also plenty of places to eat and drink, so

a whole day could get you lost wandering



GUIDE TO MUNICH

around this area of Munich. Be careful

though — it can be extremely busy at

peak times!

Riem Arcaden

Willy-Brandt-Platz 5

Tel: +49 89 93 00 60

www.riemarcaden.de/website/

The Riem Arcaden is a large indoor

shopping mall at Munich Messestadt,

which is the business/exhibition centre

district of Munich. It takes about 20

minutes on the subway to get there from

the city centre. With over 120 shops and

restaurants, ranging from department

stores to independent shops, all arranged

over three floors, there is something for

every palate.

GETTING AROUND

Public Transport

Probably the best way of getting

around Munich is on public transport.

There are buses, trams, the S-, and the

U-Bahn within Munich, as well as the

Deutsches Bahn if you would prefer

to travel further afield. The city also

puts on night services on a Friday and

Saturday evening. There are plenty

of choices for tickets depending

on what you require and these can

be purchased from service points,

customer service centres, info points,

and several private sellers (such as

kiosks). For more information on public

transport including timetables and

route maps please visit the website:

www.muenchen.de/verticals/Traffic_

Transport/227515/index.html

Bicycles

There are plenty of rental places to get

a bike for your stay in Munich and with

extensive bike lanes it is an easy way to

get around the city.

Mike’s Bike Tours and Bike Rentals

tel. +49 89 2554 39 87

Radius Tours & Bike Rental

tel. +49 89 5502 93 74

Munich Walk Tours

tel. +49 89 2423 17 67

Spurwechse Stadtführungen

tel. +49 89 6924 69 9

Internet Resources

www.muenchen.de

www.fodors.com

www.mytravelmunich.com

www.lonelyplanet.com

www.discover-munich.info


Group PublisherMike [email protected]

Editorial DirectorLaura [email protected]

Editor-in-ChiefAlasdair [email protected]

Managing EditorKate [email protected]

Assistant EditorBethany [email protected]

Sales ManagerLindsay [email protected]

Sales ExecutiveLiz [email protected]

EUROPEAN SALES OFFICE Advanstar Communications Bridgegate Pavilions, 4AChester Business Park,Wrexham Road,Chester, CH4 9QH, UKTel. +44 (0)1244 629 300Fax +44 (0)1244 678 008

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Woodbridge Corporate Plaza, 485 Route 1 South,Building F, 1st Floor, Iselin, NJ 08830 USATel. +1 732 225 9500Fax +1 732 225 0211

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Executive Vice-President, Chief Administrative Officer & Chief Financial OfficerTom Ehardt

Executive Vice-President Georgiann DeCenzo

Executive Vice-President Chris DeMoulin

Executive Vice-President Ron Wall

Executive Vice-President, Business SystemsRebecca Evangelou

Executive Vice-President, Human Resources Julie Molleston

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(including photocopying or storing it in any medium by electronic means and whether or not transiently or incidentally to some other use of this

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Meet us at Analytica 2014

Alasdair Matheson

Editor-in-Chief

Kate Mosford

Managing Editor

Mike Tessalone

Group Publisher

Liz Mclean

Sales Executive

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Sales Manager

Bethany Degg

Assistant Editor

ES413029_LCESUPP0314_034.pgs 03.27.2014 18:26 ADV blackmagentacyan

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