44th ASMS conference on mass spectrometry and allied topics … · 2017-08-26 · 44th ASMS...

44th ASMS Conference on Mass Spectrometry and Allied TopicsMay 12 - 16,1996, Portland Convention Center, Portland, OregonPreliminary ProgramFor information on registration, contact:

ASMS1201 Don Diego AvenueSanta Fe, NM 87505Telephone: (505) 989-4517Fax: (505) 989-1073e-mail: [email protected]

Abstracts for all papers listed here will be available on the ASMS Web page afterMarch 15, 1996, at the following address: http://www.asms.orgPlease note this change in the ASMS Web page address.

SUNDAY PROGRAM, May 12, 1996. Sunday sessions will be held in the Ballroom of the Oregon Convention Center.1-7 pm Registration

4-4:30 pm ASMS Meeting and Welcome

TUTORIAL SESSIONS. Open to all conference registrants.4:30-6 pm Session I

Making Ions from Molecules: Desorption Ionization, Kenneth L. Busch, Georgia Institute of TechnologyProduct Ion Formation: Collision Induced Dissociation, Stephen A. Martin, PerSeptive Biosystems

4:30-6 pm Session 11Ion Thermochemistry in Ten Easy Lessons, Robert R. Squires, Purdue UniversityFragmentation: A Conceptual Introduction to the Statistical Theory, Scott A. McLuckey, Oak RidgeNational Laboratory

6-7:30 pm Welcome Mixer

PROGRAM NOTESConference Workshops are scheduled 12:30-2 pm, Monday through Thursday of conference week.Refer to the ASMS News in this issue for a complete listing of workshops.

Title information provided here was assembledfrom electronic abstract submissiondirectly from the authors. This information has not been edited.

MONDAY ORAL SESSIONS

Monday8:30

Monday

MOA 09:30

MOA 09:50

MOA 10:10

MOA 10:30

10:50MOA 1l:1O

MOA 11:30

MOA 11:50

12:10

PLENARY LECTURE The Chilling Story of an Atomic Identity Crisis: Bose-Einstein Condensationin a Gas, Cart E. Wieman, JlLA and Department ofPhysics, University ofColorado

ELECTROSPRAY AND MALDI OF LARGE MOLECULES, Kevin Schey, presiding

Studying Noncovalent Protein-RNA Interactions by Electrospray Ionization Mass Spectrometry; ·Loo, Joseph A.;Sannes, Kristin A.; Parke-Davis PharmaceuticalResearch, Ann Arbor, MIESI Studies of Metal Binding and Noncovalent Associations in Nonheme Iron-Containing Proteins; Lei, Paula;·Arnster, Jonathan; Chemushevich, Igor; Standing, Ken; Department of Chemistry, University of Georgia, Athens, GA30602Probing macromolecular complexes by electrospray; ·Robinson , Carol; Chung, Evonne ; Grab, Michael; Radford,Sheena; Dobson, Christopher; Oxford Centre for Molecular ScienceMALDI Mass Spectrometry as a Readout of Biomolecular Interactions; ·Fitzgerald, Michael, C.; Dawson, Philip;Muir, Tom; Kent, Stephen, B. H.; The Scripps Research Institute, La Jolla, CABreakMass Spectrometric Contributions to Protein X-ray Crystallography; ··Cohen, Steven L.; Chait, Brian T.; TheRockefeller University, New York City, NYCharacterization oflmmunoglobulins Using MALDI-MS; ·Dogruel, David; Nelson, Randall W.; Williams, Peter;Merkle, Denise L.; Schenerman, Mark A.; Johnson, Syd; Pfarr, David; Arizona State UniversityElucidating the Complete Primary Structure of Glycoprotein Glycans with Mass Spectrometry; ·Orlando, Ron;Yang, Vi; Austin, Tray; Levin, Todd; CCRC, Unniversity of Georgia, Athens, GA 30602Lunch Break, Workshops, Posters

© 1996American Society for Mass 5pectrometry1044-0305/96/$15.00PH 51044-0305(96)00079-7

PRELIMINARY PROGRAM 375

MOA 4:30

MOA 4:50

MOA 5:10

MOA 5:30

Monday

MOB 09:30

MOB 09:50

MOB 10:10

MOB 10:30

10:50MOB 11:10

MOB 11:30

MOB 11:50

12:10MOB 4:30

MOB 4:50

MOB 5:10

MOB 5:30

Monday

MaC 09:30

MaC 09:50

MaC 10:10

MaC 10:30

10:50MaC 11:10

MaC 11:30

MaC 11:50

12:10MaC 4:30

MaC 4:50

MaC 5:10

Charge Detection Mass Spectrometry of Macromolecules above I Million AMU; *Fuerstenau, Stephen; Benner, W.Henry; .Lawrence Berkeley National LaboratoryDNA Sequence Information by Tandem Mass Spectrometry; *Aaserud, David, 1.; Little, Daniel, P.; Valaskovic,Gary, A.; Guan, Ziqiang; Kelleher, Neil, L.; McLafferty, Fred, W.; Comell University, Ithaca, NYAspects of Mass Spectrometric Analysis of Electroblots from 2D-PAGE separations by IR-MALDI; *Strupat,Kerstin; Eckerskom, Christoph; Schleuder, Detlev; Hochstrasser, Denis; Lottspeich, Friedrich; Hillenkamp, Franz;Institute for Medical Physics and Biophysics, University of MuensterMolecular Anatomy of Brain using Multi-Dimensional HPLC-ESIIMS Systems; *Seta, Kazuo; Isobe, Toshiaki;Nakayama, Hiroshi; Shinkai, Fumiko; Kanai, Michiko; Yamaguchi, Mihoko; Okuyama, Tsuneo; Biochemistry, TokyoMetropolitan University

NEW DEVELOPMENTS AND APPLICATIONS IN INORGANIC MASS SPECTROMETRY,Christopher Barshick, presiding

Atomic MS Of Solids By Use Of A Microsecond Pulse Discharge And A Time Of Flight Mass Analyzer; *Harrison,WilIard; University of Florida, Gainesville, FloridaRecent Developments in Elemental Mass Analysis Using FTlCR Mass Spectrometry; *Eyler, John; Goodner,Kevin; Milgram, Eric; Watson, Clifford; Dejsupa, Chadin; Barshick, Chris; Department of Chemistry, University ofFlorida, Gainesville, FloridaElectrospray Mass Spectrometry of Inorganic Ions Using Oscillating Capillary Nebulizer; *Shou, Zhenyu; Ho,Zhanying Stacy; Browner, Richard F.; School of Chem. & Biochem., Georgia Tech, Atlanta, GA 30332-0400A Second-Generation Inductively Coupled Plasma-Time-of-Flight Mass Spectrometer (ICP-TOFMS); *Hieftje,Gary M.; Li, Gangqiang; Myers, David P.; Ray, Steven J.; Mahoney, Patrick P.; Department of Chemistry, IndianaUniversity, Bloomington, IN 47405BreakElemental Analysis Using Pulsed Radio Frequency Glow Discharge Time-of-Flight Mass Spectrometry; *Steiner,Robert E.; King, Fred L.; West Virginia UniversityImproving Signal-To-Noise In Glow Discharge Ion Trap Mass Spectrometry; *Duckworth, Douglas C.; McLuckey,Scott A.; Chemical and Analytical Sciences Division, Oak Ridge-National LaboratoryGlow Discharge Ion Source Design Considerations for Particle Beam LC/MS; *DePalma, Jr., Patrick; You,Jianzhang; Marcus, R. Kenneth; Clemson UniversityLunch Break, Workshops, PostersElemental and Molecular Dual Mode Analysis by Ionspray Mass Spectrometry; *Corr, Jay; SCIEX, Concord,Ontario, CanadaGlow Discharge Mass Spectrometry and Gas Chromatography/Mass Spectrometry: ComplementaryTechniques?; *Barshick, Stacy-Ann; Barshick, Christopher, M.; Mohill, Matthew, L.; Britt, Phillip, F.; Oak RidgeNational LaboratoryQuantitation of selenium in plants,soils and sewage sludges by isotope dilution GC/MS.; *MacLeod, Fiona;McGaw, Brian; Shand, Charles; Robert Gordon University, Aberdeen, ScotlandSpeciation of Arsenic in Reference Materials by using micro-HPLC / ICPMS; *Pergantis, Spiros, A.; Heithrnar,Edward, M.; Hinners, Thomas, A.; Momplaisir, Georges-Marie; U.S. Environmental Protection Agency, Las Vegas, NV

EMERGING METHODS FOR BIOMEDICAL APPLICAnONS, Sanford P. Markey, presiding

Surface Modification and Secondary Ion Imaging of Biologic Tissue by SIMS; *Todd, Peter J.; McCandlish, CarlA.; McMahon, John M.; Oak Ridge National Laboratory, Oak Ridge, TNSubcellular imaging of ionic and molecular transport with dynamic SIMS ion microscopy; *Chandra, Subhash;Comell University, Ithaca, N.Y. 14853High-Spatial-Resolution Secondary Ion Mass Spectrometry for Biomedical Applications; *Chabala, Jan; Levi-Setti,Riccardo; University of Chicago, Chicago, ILMechanisms of Molecular Desorption Induced by keY Ion Bombardment of Organic and Biological Surfaces;*Riederer, Donald E.; Chatterjee, Reema; Rosencrance, Scott W.; *Postawa, Zbigniew; Dunbar, Timothy D.; Allara,David L.; Winograd, Nicholas; The Pennsylvania State UniversityBreakSecondary Ion Imaging of Stable Isotopes in Biological Tissues: Progress and Prospects; *Linton, Richard W.;Lazof, Dennis 8.; Goldsmith, Jack G.; Gillen, Gregory; Rufty, Thomas W.; Department of Chemistry, University ofNorth Carolina, Chapel Hill, NCReplacing 14C with stable isotopes in drug metabolism studies; *Abramson, Fred; Teffera, Yohannes; Kusmierz,Josef; Steenwyk, Rick; Pearson, Paul; George Washington University, Washington DCOrganic Ion Imaging by High Performance Time-of-Flight Secondary Ion Mass Spectrometry; *Odom, Robert;Charles Evans & Associates Redwood City, CA 94063Lunch Break, Workshops, PostersCoupling Time-of-Flight MALDI with Thin-Layer Chromatography; *Hercules, David M.; Vanderbilt University,Nashville, TN 37235From 1-0 and 2-0 polyacrylamide gels to MALDI-MS; *Ogorzalek Loo, Rachel; Mitchell, Charles; Stevenson,Tracy; Loo, Joseph; Andrews, Philip; Dept. of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109Use of Bioreactive Probe Tips in the MALDI Mass Spectrometric Characterization of Proteins.; *Nelson, Randall;Dogruel, David; Krone, Jennifer; Lewis, Kathleen; Williams, Peter; Arizona State University

376

MOC 5:30

Monday

MOD 09:30

MOD 10:1010:50

MOD 11:10

12:10MOD 4:30

MOD 5:10

Monday

MOE 09:30

MOE 10:10

MOE 10:30

10:50MOE 11:10

MOE 11:30

MOE 11:50

12:10MOE 4:30

MOE 4:50

MOE 5:10

MOE 5:30

Monday

MOF 09:30

MOF 10:10

MOF 10:30

10:50MOF 11:10

MOF 11:30

MOF 11:50

12:10MOF 4:30

MOF 4:50

MOF 5:10

MOF 5:30

44TH ASMS CONFERENCE ON MASS SPECTROMETRY

ICR Spectra ofOlegonucleotide-Primer Generated with the EPID Method; Spiess, Iris; *Wanczek, Karl P.; Inst. ofInorg. and Phys. Chemistry, University of Bremen, 0-28334 Bremen

HISTORY OF VARIOUS MASS SEPARATION TECHNIQUES, Michael Grayson, presiding

Preparative Scale Mass Spectrometry: A Brief History of the Calutron; *Yergey, Alfred; Philips, Lawrence;National Institute of Child Health and Human Development, NIHMagnetic and Electric Sector Mass Analyzers; *Futrell, Jean;; University of Delaware, Newark, DEBreakTime-of-Flight = Fifty Years: the Search for a Larger Mass Range and Better Resolution; *Standing, Kenneth G. ;Physics Dept., University of Manitoba, Winnipeg, Canada R3T2N2Lunch Break, Workshops, PostersA Historical Review ofthe Science and Technology of Quadrupole Mass Spectrometry; *Story, Michael; ThermoInstrument Systems IncEfficiency Improvements in Mass Separation Techniques; *McLafferty, Fred W.; Cornell University, Ithaea, NY

REACTIONS OF GAS PHASE IONS, Hilkka Kenttiimaa, presiding

Holy Grails in Gas-Phase Ion Chemistry: A Personal View; *Schwarz, Helmut; Department of Chemistry, TechnicalUniversity of Berlin, BerlinProtonation Sites in Nitrogen Heterocycles by Neutralization-Reionization Mass Spectrometry; Nguyen, Viet;*Turecek, Frantisek; Wolken, JilI; University of Washington, SeattleMechanisms for Propene Expulsion from Ionized Propyl Phenyl Ethers, C3H70Ph+.; *Morton, Thomas Hellman;Traeger, John c.; University of California, RiversideBreakGas Phase Reactions Between Charged Lewis Acids and Glycine and Other Small Biomolecules.; *O'Hair, Richard;Freitas, Michael; Schmidt, Joseph; WilIiams, Todd; Department of Chemistry, Kansas State University, Manhattan, KS66506-3701The Role of Charge State on the Conformation and Dissociation Energetics ofBiomolecule Ions; *WilIiams, Evan;Price, WilIiam; Schnier, Paul; Gross, Deborah; University of California, BerkeleyInfluence of N- and C-Terminal Arginines on Peptide Decay: Evidence of Intramolecular H-Bonding; *Russell,David H.; Gimon-Kinsel, Mary E.; Texas A&M University, College StationLunch Break, Workshops, PostersIon-ion and Ion-molecule Reactions of Multiply Charged Ions in the Paul Trap; *McLuckey, Scott A.; Stephenson,Jr., James L.; Herron, William J.; Goeringer, Douglas E.; Oak Ridge National Laboratory, Oak Ridge, TNPotential energy surfaces of the reactions of doubly charged ions: a computational approach.; *Gronert, Scott; SanFrancisco State University, San Francisco, CAHydration Enthalpies of Electrospray-Generated Doubly Charged Gas Phase Ions; Blades, Arthur, T.; Klassen,John, S.; *Kebarle, Paul; Department of Chemistry, University of Alberta, Edmonton, CanadaSIFT/CID Studies of "Fuzzy-Ball" and "Ball-and-Chain" Derivatization ofC60 Cations.; Baranov, Vladimir;Hopkinson, Alan, C.; *Bohme, Diethard, K.; York University, North York, Ontario, Canada

MOVING MASS SPEC OUT OF THE LAB: IN-SITU, ON-LINE AND PORTABLE MSAPPLICATIONS, Steven Doherty, presiding

On-line monitoring reaction monitoring using membrane introduction mass spectrometry; *Cooks, R. G.; Johnson,R. C. ; Srinivasan, N.; Kasthurikrishna, N.; Wong, P.S. H.; Purdue University, West LafayetteCopolymer Membranes for the MIMS Analysis of Volatile Organic Compounds; *Ohorodnik, Susan; Anderson,Mark; Callahan, John; Naval Research LaboratoryDevelopment of an on-site system for the detection of gases and organic compounds in water; Matz, Gerhard;*Kibelka, Gottfried; Technical University Hamburg-HarburgBreakEvaluation of ion sources for online analysis of gasphase organics in dynamic sample streams; *Dearth, Mark; FordMotor Company, Maildrop SRL 3179Development of a Hand-Portable Photo-Ionization Time-of-Flight Mass Spectrometer; *Dieckman, Stephen;Bostrom, Gregory; Waterfield, L. Glen; Jendrzejezyk, Joseph; Raptis, A. C. (Paul); Argonne National Laboratory,Argonne llIinoisRounded hyperbolic quadrupoles RHQ (tm) implemented in a novel MS-MS type instrument; *Steiner, Urs; Jones,Larry; Sokolow, Steve; Bear Instruments, IneLunch Break, Workshops, PostersMS and MS/MS Performance of a Field-Portable Ion Trap Mass Spectrometer for CWC Treaty Compounds;*Lammert, Stephen A.; Palausky, M. Andi; Oak Ridge National LaboratoryIn-situ Measurement of Size and Composition of Airborne Particulate Matter using a Portable ATOFMS; *Gard,Eric; Dienes, Tas; Fergenson, David; Morrical, Brad; Prather, Kimberly A.; Department ofChemitry, University ofCalifornia Riverside 92521On-Line Chemical Process and Emissions Monitoring with a Transportable MBMS Instrument; *Ratcliff,Matthew; Gratson, David; Gebhard, Steven; French, Richard; Patriek, Joseph; Meglen, Robert; National RenewableEnergy Laboratory (NREL), Golden, COA Field GClIon Trap Mass Spectrometer - From Concept to Customer; *Cisper, Mary; Hemberger, Philip; LosAlamos National Laboratory, Los Alamos, NM

PRELIMINARY PROGRAM

TUESDAY ORAL SESSIONS

377

Tuesday8:30

Tuesday

TOA 09:30

TOA 10:10

TOA 10:30

10:50TOA 11:10

TOA 11:30

TOA 11:50

12:10TOA 4:30

TOA 4:50

TOA 5:10

TOA 5:30

Tuesday

TOB 09:30

TOB 10:10

TOB 10:30

10:50TOB 11:10

TOB 11:30

TOB 11:50

12:10TOB 4:30

TOB 5:10

TOB 5:30

Tuesday

TOC 09:30TOC 10:10

TOC 10:3010:50

PLENARY LECTURE Ion Games in a Magnetic Gymnasium: Attomoles to MegaDaltons, Alan G.Marshall, National High Magnetic Field Laboratory, Florida State University

ELECTROSPRAY AND MALDI OF SMALL MOLECULES, Dominic Desiderio, presiding

MALDI-ITMS as a Tool for Biomolecule Structure Analysis; *Chait, Brian T.; Qin, Jun; The Rockefeller University,1230 York Ave., New York, NY 10021Real Time Protein Identification to Guide Tandem MS Investigations of Unseparated Peptide Mixtures; *Wilm,Matthias; Shevchenko, Andrej; Mann, Matthias; European Molecular Biology LaboratoryInvestigations of Protein Structure using Bioreactive Probe Tips and Quantitative MALDI; *Lewis, Kathleen;Krone, Jennifer; Dogruel, David; WiIliams, Peter; Nelson, Randall; Arizona State UniversityBreakCharacterization of Synthetic Peptides using MALDI and Electrospray Mass Spectrometry; *Carroll, James;Brostowin, Janet; Beavis, Ronald; The Skirballlnstitute, New York University Medical Center, New York, NYThe Development of ESI-TOF and It's Comparison with MALDI-TOF for the Characterization of Peptides.: .*Vestal, Marvin; Verentchikov, Anatoli; Hsieh, Frank; Gabeler, Steve; Zhou, Joe; Takach, Edward; Martin, Stephen;PerSeptive Biosystems, Inc., Framingham, MAMALDI mass spectrometry of peptidoglycan oligomers after size exclusion chromatography and HPLC:*Allmaier, Gilnter; Zenker, Andrea; Pfanzagl, Beatrix; Loffelhardt, Wolfgang; Institute for Analytical Chemistry,University of Vienna, Vienna, AustriaLunch Break, Workshops, PostersTMPP-Derivatives: A New Generation of Charged Derivatives for Desorption Ionization MS; *Watson, J.T.;Huang, Z.-H.; Liao, P.-C.; Wu, J.; Roth, K.D.W.; Lavine, G.; Gage, D.A.; Allison, J.; Dept. of Biochemistry, MichiganState University, East Lansing, MI 48824Chracterization of Bovine Adrenal Modullary Peptides by using ESI-MS and LC/ESI-MS; *Dass, Chhabil;Department of Chemistry, The University of Memphis, Memphis, TN 38152Coordination sites of Alkali Metals Complexed to Oligosaccharides Dictate Fragmentation Behavior; *Cancilla,Mark T.; Penn, Sharron G.; Carroll ,James A.; Lebrilla, Carlito B.;; Department of Chemistry, University of California,DavisMALDlI PSD Peptide Fragment-Ion Tagging and Mass Fingerprinting of Placental Proteins from 2D PAGE:*Clauser, Karl R.; Foulk, Russell A.; Baker, Peter; Fisher, Susan J.; Burlingame, Alma L.; Department ofPharmaceutical Chemistry, Univ. of California, San Francisco

FRONTIERS IN ISOTOPE RATIO MEASUREMENTS, Douglas Duckworth, presiding

Mechanisms in Thermal Ionization; *Delmore, Jim; Appelhans, Tony; Huett, Tom; Olson, John; Idaho NationalEngineering LaboratoryIonization Mechanism and Theory of Thermal Ionization Sources, On the Road to Higher Efficiency: *Olivares,Jose; Duan, Yixiang; Los Alamos National Laboratory, Los Alamos, NMEnvironmental and nuclear applications of isotope ratio mass spectremetry: *Wacker, J.F.; Farmer, O.T.; Gerlach,D.C.; Kelley, J.M.; Koppenaal, D.W.; Smith, M.R.; Pacific Northwest National LaboratoryBreakIsotope Ratio Measurements Using a Multi-collector Inductively Coupled Plasma Mass Spectrometer; *Smith,David H.; Duckworth, Douglas C.; Barshick, Christopher M.; Riciputi, Lee R.; McBay, E.H.; McPherson, R.L.; Turner,M.L.; Valiga, R.E.; Chemical and Analytical Sciences Division, Oak Ridge National LaboratoryRF-Glow Discharge Ion Trap Mass Spectrometry- A Look at Elemental Analysis and Isotope Ratios: *Eanes,Ritchie; Marcus, R. Kenneth; Clemson University; Clemson, SCPerformance Test of a Moving Wire Interface for Isotope-Ratio-Monitoring LCMS; Brand, WiIli A.; *Dobberstein,Peter; Pesch, Reinhold; Schroeder, Ernst; Finnigan MAT GmbH, D-28197 Bremen, GermanyLunch Break, Workshops, PostersA novel approach for studying calcium fluxes at subcellular scale: SIMS imaging ofstable isotopes; *Chandra,Subhash; Cornell University, Ithaca, N.Y. 14853High-Precision DIU Measurement From Organic Mixtures By Continuous-Flow IRMS Using A Pd Filter;*Tobias, Herbert; Brenna, J. Thomas; Division of Nutritional Sciences, Cornell University, Ithaca NYHair Analysis for Detection of Drugs of Abuse; *Cairns, Thomas; Cheng, Chen-Chih; Scholtz, Henry; Wang, WenLing; Psychemedics Corporation, 5832 Uplander Way, Culver City, California 90230

MASS SPECTROMETRY IN PHARMACOLOGY AND TOXICOLOGY, Thomas Baillie,presiding

The role of mass spectrometry in drug metabolism and pharmacokinetics; *Blair, Ian A.;; Vanderbilt UniversityLC/MSIMS of Buprenorphine and Norbuprenorphine in Human Plasma and Hair: *Laycock, John; Spanbauer,Alan; Crouch, Dennis; Wilkins, Diana; Moody, David; Foltz, Rodger; Center for Human Toxicology, University ofUtah, Salt Lake City, UTTandem mass spectrometry in natural products discovery; *Julian, Jr., Randall K.; EIi Lilly and Company.Break

378

TOC 11:10

TOC 11:30

TOC 11:50

12:10TOC 4:30

TOC 4:50

TOC 5:10

TOC 5:30

TuesdayTOD 09:30

TOD 09:50

TOD 10:10

TOD 10:30

10:50TOD 11:10

TOD 11:30

TOD 11:5012:10

TOD 4:30

TOD 4:50

TOD 5:10

TOD 5:30

TuesdayTOE 09:30

TOE 09:50

TOE 10:10

TOE 10:30

10:50TOE 11:10TOE 11:30

TOE 11:50

12:10TOE 4:30


New Automated Data Acquisition and Processing Tools for Pharmaceutical Research Utilizing APIfMS/MS;*Shushan, Bori; Covey, Tom; Alien, Mark; Anacleto, Joe; Bonner, Ron; PE SClEX, Concord, OntarioRapid In vivo Pharmacokinetic Screening of Drug Discovery Mixtures Using APCI LC/MS; *Halm, Kathy;Adkison, Kim; Berman, Judd; Shaffer, Joel; Glaxo Wellcome, Inc.Rapid Screening Procedures for Metabolic Stability and Biotransformation of; *King, Richard; Fernandez, Carmen;Baillie, Thomas; Owens, Kevin; Merck Research Laboratories, West Point, PALunch Break, Workshops, PostersESIIMS Studies of Metabolic Enzymes: Elucidation of Mechanism and Design of Enzyme Inactlvators; *Jones, A.Daniel; Borhan, Babak; Zheng, Jiang; Mitchell, Alyson E.; Pinot, Franck; Grant, David F.; Kurth, Mark J.; Hammock,Bruce D.; University ofCalifornia-Davis, Davis, CACovalent Sequestration of Mechlorethamine by Metallothionein; *Antoine, Miquel; Fabris, Daniele; Han, Mark;Fenselau, Catherine; UMBC, Baltilmore, MDCovalent Binding of Reactive Eicosanoid Intermediates with Target Proteins; *Waugh, Russell; Clay, Keith;Murphy, Robert; National Jewish Center for Immunology and Respiratory Medicine, Denver, CO.The analysis ofthe urinary mercapturate ofvinyl chloride using ID-HPLC-MS/MS; *Shealy, Dana B.; Ashley,David L.; Centers for Disease Control and Prevention

TOF METHODS FOR DNA SEQUENCING, Robert Cotter, presidingMALDI-TOF-MS-a New Paradigm for DNA Detection: Applications in DNA Diagnostics and DNA Sequencing;*Koster, Hubert; University of HamburgVarious TOF Mass Spectrometric Approaches for DNA Sequencing; *Chen, Winston; Zhu, Yi-Fei; Taranenko,Nelli; Allman, Steve; Oak Ridge National LaboratoryDNA Analysis for Rapid Genetic Screening with MALDI TOF Mass Spectrometry; *Liu, Yan-Hui; Bai , Jian; Zhu,Yongdong; Liang, Xiaoli; Lubman, David M.; Department of Chemistry, The University of Michigan, Ann Arbor, MI48109Characterization of Oligonucleotide Strands by Enzymatic Digestion and MALDI-TOF; *Bentzley, Catherine;Johnston, Murray; Larsen, Barbara; Gutteridge, Steven; University of Delaware, Newark, DEBreakFragmentation in the MALDI-TOF Analysis of Nucleic Acids; *Smith, L10yd M.; Nelson, Christine; Tang, Wei; Zhu,Lin; Department of Chemistry, University of Wisconsin-MadisonDNA-Cycle-Sanger-Sequencing by MALDI-TOF-MS with nucleotides modified for enhanced ion stability;*Nordhoff, Eckhard; Kirpekar, Finn; Hahner, Stephanie; Kristiansen, Karsten; Roepstorff, Peter; Hillenkamp, Franz;Department of Molecular Biology, OdenseFragmentation of DNA in MALDI; *Chou, Chau-Wen; Williams, Peter; Arizona State UniversityLunch Break, Workshops, PostersDNA analysis using time-lag focusing MALDI TOFMS; Dai, Yuqin; Whittal, Randy; *Li, Liang; Department ofChemistry, University of AlbertaAnalysis and sequencing DNA by delayed extraction MALDI-TOF mass spectrometry.; *Smirnov, Igor; Roskey,Mark; Juhasz, Peter; Stanick, Wendy; Takach, Edward; Martin, Stephen; Haff, Lawrence; PerSeptive BioSystems, Inc.Framingham, MADetailed Characterization of Antisense DNA Oligonucleotides; *Keough, T.; Shaffer, J.D.; Lacey, M.P.; Riley, T.A.;Marvin, W.B.; Scurria, M.A.; Hasselfield, J.A.; Hesselberth, E.P.; The Procter and Gamble Co.MALDI-TOFMS of Double-Stranded DNAs immobilized on Solid Surfaces; *Tang, Kai; Fu, Dongjing; Kotter,Sven; Cotter, Robert; Cantor, Charles; Koster, Hubert; Sequenom Inc., Boston, MA

HOST-GUEST INTERACTIONS, DavidDearden, presidingEnergy-resolved CID threshold studies of metal-polyether complexes; *Sunderlin, Lee; Do, Khanh; Klein, Tim;Northern lIIinois UniversityGuided Ion Beam Studies of the Binding Energies for Alkali Metal Ion Crown Ether Complexes; *Armentrout,Peter 8.; More, Michelle; Ray, Doug; Feller, David; Glendening, Eric; Chemistry Department, University of Utah, SaltLake City, UT 84112Formation and binding energies of metal-ion/coronene complexes and sandwiches; *Dunbar, Robert C.; Pozniak,Boguslav P.; Klippenstein, Stephen J.; Case Western Reserve University, Cleveland, OHMALDI Analysis of Crown Ether Interactions with Cations; *Fang, Tong; Lynn, Jr., Bert C.; Mississippi StateUniversityBreakMultiple Binding Interactions in Gas-Phase Complexes; *Brodbelt, Jennifer; University of Texas, Austin, TX.Host-Guest Interactions between Cavitands or Calixarenes and Target Organic Molecules or Ions; *Vincenti,Marco; Dalcanale, Enrico; Dipartimento di Chimica Analitica, Universita di Torino, Torino, ItalyChiral Molecular Recognition in Host-Guest Complexation detected by FABMS; *Sawada, Masami; Takai, Yoshio;Yamada, Hitoshi; Nishida, Jun; Naemura, Koichiro; The Institute of Scientific and Industrial Research, Osaka UniversityLunch Break, Workshops, PostersReaction of Mixed Alkaline Earth Clusters with Crown Ethers: Elementary Molecular Recognition?; *Pope, R.Marshall; Shen, Nanzhu; Dearden, David; Department of Chemistry and Biochemistry, Brigham Young Univ., Provo,UT


TOE 4:50

TOE 5:10

TOE 5:30

Tuesday

TOF 09:30

TOF 10:10

TOF 10:30

10:50TOF 11:10

TOF 11:30

TOF 11:50

12:10TOF 4:30

TOF 4:50

TOF 5:10

TOF 5:30

Wednesday8:30

Wednesday

WOA 09:30

WOA 09:50

WOA 10:10

WOA 10:30

10:50WOA 11:10

WOA 11:30

WOA 11:50

12:10WOA 4:30

WOA 4:50

WOA 5:10

Dependence ofthe Na+ and Cu+ affinities ofsimple biomolecules on sequence and stereochemistry; ·Wesdemiotis, 'Chrys; Cerda, Bias A.; Deng, Wei; Chemistry Department, The University of Akron, Akron, Ohio, 44325-3601ESI Mass Spectrometric Studies of Cyclodextrin - Peptide Complexes and Adducts; ·Prokai, Laszlo; Eyler, John;Kage, David; Nawrocki, Joseph; Watson, Clifford; Myung, Seung-Woon; Ramanathan, Ragulan; University of Florida,GainesvilleFactors governing the strength of non-covalent interactions in gas-phase cyclodextrin complexes; • Penn, SharronG.; He, Fei; Green, M. Kirk; Lebrilla, Carlito B.; Department of Chemistry, University of California, Davis

DIRECT SAMPLING MASS SPECTROMETRY: FUNDAMENTALS AND APPLICATIONS,Dingneng Wang, presiding

The Skimmer in Direct Sampling Mass Spectrometry; ·Miller, David;; University of California at San Diego, LaJollaSampling Methods For Supersonic Molecular Beam-Mass Spectrometry; ·Amirav, Aviv; Dagan, Shai; Tel AvivUniversityDirect Sampling Tandem Mass Spectrometry ofPremixed Flames; "'Egsgaard, Helge; Larsen, Elfinn; Ris; NationalLaboratory, DK-4000 Roskilde, DenmarkBreakDesign and Construction of an Ion Trap Mass Spectrometer System for On-line Gas Emission Analysis; "'Scoggin,Joe e.; Lynn, Jr., Bert C.; Mississippi State UniversityEvaluation of Direct Sampling Ion Trap MS for In-Field Analysis ofVOCs in Air, Water and Soil; "'Wise, Marcus;Thompson, Cyril; Yelton, Richard; Oak Ridge National LaboratoryDirect Analysis of Environmental Samples by Selective Sorbents and Laser Mass Spectrometry; Cisper, M.E.; Earl,W.L.; Garrett, A.W.; Gill, e.G.; "'Hemberger, P.H.; Nogar, N.S.; Los Alamos National LaboratoryLunch Break, Workshops, PostersPyrolysis-Quadrupole Ion Trap Mass Spectrometry of Pathogenic Bacteria; "'Basile, Franco; Beverly, Michael B.;Voorhees, Kent J.; Hadfield, Ted L.; Department of Chemistry, Colorado School of Mines, Golden, ColoradoOn-Site Mapping of Volatile Organic Pollutant Plumes using Membrane Introduction Mass Spectrometry;"'Bauer, Scott; Griffin, Timothy; Bauer, Janice; MIMS Technology Incorporated, Palm Bay, FloridaTwo-Step Laser Mass Spectrometry for in-situ Chemical Analysis of Complex Mixtures; "'Zenobi, Renato; Zhan,Qiao; Haefliger, Olivier; ETH ZYrichAtmospheric Pressure Ionization Flow Injection Analysis Orthogonal Time of Flight Mass Spectrometry;'"Andrien, Jr., Bruce: Dresch, Thomas; Haren, Patrick; Whitehouse, Craig; Analytica of Branford, Inc. 29 Business ParkDrive, Branford, CT 06405

WEDNESDAY ORAL SESSIONS

PLENARY LECTURE Biomedical Mass Spectrometry: Blood, Sweat and Urine, Catherine C.Fenselau, Department ofChemistry and Biochemistry, University ofMaryland Baltimore County

FUNDAMENTALS OF MALDI, Werner Ens, presiding

Early Time Frame Metastable Ion Decay In MALDI; "'Brown, Robert; Reiber, Duane; Feng, Jinhua; Utah StateUniversity, Logan UT 84322-0300Novel method for the measurement of the initial velocity of ions generated by MALDI; '"Juhasz, Peter; Martin,Stephen; Vestal, Marvin; PerSeptive Biosystems, Framingham, MAIon Simulation and Experimental Investigation of the Time-Lag Focusing MALDI TOF Mass Spectrometer;"'Russon, Larry; Whittal, Randy; Li, Liang; Department of Chemistry, University of Alberta, EdmontonDelayed Extraction Time-of-Flight MALDI in Axial and Orthogonal Geometries; "'Dworschak, Ragnar; Ens,Werner; Spicer, Vie; Standing, Kenneth G.; Department of Physics, University of Manitoba, Winnipeg, Canada R3T2N2BreakGas-phase cationization versus solid phase preformed ions in MALDI; "'Dubois, Frederic J.; Knochenmuss, Richard;Steenvoorden, Ruud J.J.M.; Breuker, Kathrin; Zenobi, Renato; Organic Chemistry Institute, ETH Zurich, SwitzerlandProton affinities of five commonly used MALDI matrices.; "'Nelson, Christine M.; Smith, L10ydM.; Crellin, KevinC.; Berry, Jama!; Beauchamp, Jesse L.; University of Wisconsin, Madison, WI 53705Bioreactive Grafted Polymeric Films on Modified Steel Platforms for Laser Desorption of Biomolecules; Ching,Jesus; Voivodov, Kamen; Vip, Tai-Tung; "'Hutchens, T. William; University of California, DavisLunch Break, Workshops, PostersSequencing of a Tap-Dependent Leader Peptide Using a Curved-Field-ReOectron TOF Mass Spectrometer;"'Woods, A.S.; DeCloux, A.; Cordero, M.; Soloski, MJ.; Cotter, RJ.; Pharmacology, Johns Hopkins UniversityMedical School, Baltimore, MDU1trahigh-resolution Fourier transform mass spectrometry of biomolecules above m/z 5000; "'McIver Jr., RobertT.; Li, Yunzhi; Hunter, Richard L.; Department of Chemistry, University of California, Irvine, CA 92717Examining the MALDI Ion Formation Process(es); "'Edmondson, Ricky D.; Gillig, Kent J.; Russell, David H.; TexasA&M University, College Station

380

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Wednesday

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New Technique for Trapping of MALDl Generated Ions Inside an ICR Cell; *Knobeler, Markus; Wanczek, KarlPeter; Institute oflnorg. and Phys. Chemistry, University, D-28334 Bremen

ENERGY AND PETROCHEMICALS, DonaldDrlnkwater, presidingAge-Dating Hydrocarbon Contaminantion Using High Precision Lead Isotope Analyses; ·Hurst, Richard W.;CHEMPET RESEARCH CORPORATIONThermal Desorption - Photoionization Mass Spectrometry of Coals and Soils; • Johnston, Murray; Bookwalter,Craig; University of Delaware, Newark, DECharacterization ofParaftinlNaphthene Hydrocarbons by LC Coupling with Field Ionization MS; .Hsu, ChangSamuel; Liang, Zhenmin; Blum, Saul; Grosshans, Peter; Robbins, Winston; Exxon Research and Engineering CompanyBreakTotal olefin in gasoline determined by mass spectrometry and hydrogenation.; *Cheng, Michael; Hudson, James;Drinkwater, Don; Nero, Vince; Chevron Research and Technology Company and Texaco ResearchThe Analysis ofOlefins by Selective Chemical Ionization MS; *Roussis, S.G.; Fedora, J.W. ; Imperial Oil, SamiaResearch Centre, Samia, Ontario, Canada, N7T 7M IHydrocarbon Type analysis of cat cracked gasoline by TDNOCI GC/MS; *Dzidic, Ismet; Petersen, HA; ShellDevelopment CO.,Houston,TX.Lunch Break, Workshops, PostersThe Identification ofOrgano - Molybdenum Compounds in Lubricating Oil by ESI / MS; *Nero, Vincent;Drinkwater, Donald; Texaco R&D, PO Box 509, Beacon, NY 12508Analysis of Hydrocarbon Polymers by MALDl·FTMS; *Pastor, Salvador; Wilkins, Charles L.; University ofCalifomia, RiversidePredicting Optimum Resolving Powers for Homolog Type Analysis of Fossil-Fuel Distillates; *Scheppele, Stuart;Research Resources Center, University of Illinois Chicago, Chicago, ILLow eV-HR/MS Analysis of a Porphyrin Fraction Separated from Cerro Negro Petroleum by LC Methods;*Grigsby, Ronald D.; BDM-OklahomaINIPER, Bartlesville, Oklahoma

MS BASED STRATEGIES FOR CHARACTERIZING BIOMOLECULE-LIGAND

INTERACTIONS, Joseph Loo,presidingAffinity Selection- Mass Spectrometry: Identification of Lead Compounds from Combinatorial Libraries;*Huebner, Verena D.; Kaur, Surinder; McGuire, Lisa; Tang, Dahzi; Dollinger, Gavin; Chiron Corporation, Emeryville,CAPulsed ultrafiltration/electrospray MS: a new method for screening combinatorial libraries; *van Breemen,Richard B.; Huang, Chao-Ran; Nikolic, Dejan; Wood bury, Charles P.; Zhao, Yong-Zhong; Venton, Duane L.;University of Illinois at Chicago, Chicago, IllinoisMeasurement of macromolecular binding constants using electrospray mass spectrometry; *Griffey, Richard;Greig, Michael; Cummins, Lendall; Gaus, Hans; Sasmor, Henri; Isis Pharmaceuticals Carlsbad, CA 92008BreakStudies of Non-Covalent Interactions by Time-of-Flight Mass Spectrometry; *Chemushevich, Igor V.; Krutchinsky,Andrew N.; Ens, Werner; Standing, Kenneth G.; University of Manitoba, Winnipeg Manitoba Canada R3T 2N2Non-Covalent Protein Interactions and HID Exchange Reactions on Target characterized by UV-MALDI-MS;*G1ocker, Michael 0.; Jetschke, Martina R.; Bauer, Sebastian HJ.; Volz, Jurgen; Przybylski, Michael; UniversityKonstanz Chemistry Dept. POBox5560M73I , D-78434 Konstanz GermanyInterfacing BIA with MALDl Mass Spectrometry; *Krone, Jennifer; Nelson, Randall; Dogruel, David; WiIliams,Peter; Granzow, Russ; Arizona State UniversityLunch Break, Workshops, PostersMS/MS as a valuable tool for determining the sequence specificity of DNA-interactive agents.; lannitti, Paula;Wickham, Geoff; Boschenok, Jacqui; Hick, Larry A.; *Sheil, Margaret M.; University of Woliongong, Wollongong,NSW AustraliaProbing the influence of mutations on the stability of a cluster-ferredoxin complex; R migy, Herv ; Jaquinod, Michel;P tillot, Yves; Hurley, John; Gagnon, Jean; *Forest, Eric; Institut de Biologie Structurale CEA-CNRS, Grenoble, FranceIn situ monitoring by ESI-MS ofreactions of drugs with zinc finger proteins; *Hathout, Yetrib; Fabris, Daniele;Fenselau, Catherine; Structural Biochemistry Center, University of Maryland Baltimore CountyInvestigation of DNA-Protein Interactions Relevant to DNA Repair; ·Harms, Amy C.; Severs, Joanne C.; Liu,Chuanliang; Pasa-Tolic, Ljijana; Hofstadler, Steven A.; Smith, Richard D.; Pacific Northwest National Laboratory,Richland, WA 99352

ION TRAPS: FUNDAMENTALS AND APPLICATIONS, Steve Lammert, presiding

Towards an Understanding of Resonant Excitation in a Quadrupole Ion Trap; *March, Raymond E.; Lausevic,Mila; Splendore, Maurizio; Liere, Philippe; Tabet, Jean-Claude; Department ofChemisry, Trent University,Peterborough, ON, Canada, K9J 7B8A first-order model for collision-induced dissociation in the Paul ion trap; *Goeringer, Douglas; McLuckey, Scott;Oak Ridge National Laboratory, Oak Ridge, TN 37831-6365Methods for Cooling Trapped Ions or Electrons; *Li, Guo-Zhong; Guan, Shenheng; Marshall, Alan G.; NationalHigh Magnetic Field Lab, Florida State Univ., Tallahassee, FLThe Effect of Heavy Gases on the Dissociation Patterns of Peptide Ions in a Quadrupole Ion Trap; *Vachet,Richard W.; G1ish, Gary L.; University ofNorth Carolina, Chapel Hill


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Wednesday

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BreakImprovements in Performance of MALDI/Quadrupole Ion Trap Designed for Biological Applications.;*Doroshenko, Vladimir M.; Cotter, Robert J.; Pharmacology, Johns Hopkins University Medical School, BaltimoreMDTechnical Aspects of Matrix-assisted Laser Desorption/Ionization Ion Trap Mass Spectrometry; *Qin, Jun; Chait,Brian; The Rockefeller University, 1230 York Ave., New York, NY 10021Reactions of Multiply Charged Biological Cations with Singly Charged Anions in the QITMS; *Stephenson Jr.,James L.; McLuckey, Scott A.; Oak Ridge National Laboratory, Oak Ridge, TNLunch Break, Workshops, PostersFundamental Studies of Ion Injection and Trapping of Eledrosprayed Ions on a Quadrupole Ion Trap;*Quannby, Scott T.; Yost, Richard A.; *Schwartz, Jae C.; Syka, John E. P.; University of Florida, Gainesville, FL IFinnigan MAT, San Jose, CACharacterization of Combinatorial Chemical Libraries by Ion Trap-Tandem Mass Spectrometry; *Henion, Jack;Nedved, Michael; Habibi, Sohrab; Comell University, Ithaca, NYMany-particle computer simulations of ion motion in Paul and ICR ion traps; *Mitchell, Dale W.; Smith, RichardD.; Pacific Northwest National Laboratory, Richland WANon-linearity of ion oscillations in ion trap: the key to the mystery of ultra-high mass resolution; *Makarov,Alexander; General Physics Institute, Moscow, Russia

ION STRUCTURE AND ENERGETlCS, Steven Kass, presiding

Conformations of Exotic Species in the Gas Phase: An Intersection of Experiment and Theory; *Bowers, MichaelT.; Wyttenbach, Thomas; Lee, Seong Hoon; Department of Chemistry, University ofCalifomia at Santa BarbaraNegative Ion Photoelectron Spectroscopy of Transition Metal Trimers; *Leopold, Doreen; Simson, Alex; Green,Susan; University of MinnesotaPhotoelectron Spectroscopy of Small Cluster Anions; Dipole Bound, Ground State Systems; Hendricks, Jay;deClercq, Helen; Lyapustina , Svetlana; Fancher, Chuck; Lippa, Tim; Collins, John; *Bowen, Kit; Johns HopkinsUniversityBreakThe Proton Affinity and Absolute Heat of Formation of Trinuoromethanol; Chyall, Leonard J.; *Squires, Robert R.;Purdue University, Department of Chemistry, West Lafayette, IN 47907Reaction Energetics: Nucleophilic Displacement and Proton Transfer; DeTuri, Vincent F.; Hintz, Paul A.; *Ervin,Kent M.; Department of Chemistry, University of Nevada, RenoSize and Structural Effects in the Energetics of Gas Phase Ion-Molecule Association Reactions; *McMahon, Terry;Hoffman, Tim; Department of Chemistry; University of Waterloo; Waterloo, Ontario; CANADALunch Break, Workshops, PostersIon chemistry of protonated lysine and derivatives; *Harrison, Alex. G.; Yalcin, Talat; University of Toronto,Toronto, Canada M5S IAIGeneration, Characterization, and Decomposition of Silanol Cations; Nygaard, Dawn; Wilcox, Bruce; *Jacobson,Denley; North Dakota State Univeristy, FargoPhotodissociation Spectroscopy and Dynamics of the N202- Anion; *Osbom, David; Leahy, David; Cyr, Douglas;Neumark, Daniel; University ofCalifomia, Berkeley, and Lawrence Berkeley LaboratoryConformation of Gas-Phase Lysozyme Ions As Revealed by Surface-Impact Defects; *Sullivan, Patrick A.;Reimann, Curt T.; Axelsson, Jan; Quist, Arjan P.; Hakansson, Per; Roepstorff, Peter; Sundqvist, Bo U.R.; Division ofIon Physics, Uppsala University, Uppsala

MASS SPECTROMETRY AND DNA ADDUCTS, Jackson Lay, presiding

Quantitation of carcinogen-DNA adducts in humans: the role of mass spectrometry; *Hecht, Stephen S.; AmericanHealth FoundationDNA adducts vs protein adducts as carcinogen biomarker» in humans.; *Wishnok, John S.; MIT Division ofToxicology, Cambridge, MA 02139Molecular dosimetry of DNA and hemoglobin adducts using mass spectrometry; *Swenberg, lames; Christova,Nadia; Ranasinghe, Asoka; Scheller, Nova; Tretyakova, Natalia; Wu, Kuen-yu; Yen, Robert; University of NorthCarolina at Chapel HillBreakMolecular Dosimetry of Endogenous Carcinogens; *Chaudhary, Ajai K.; Kowalski, Eileen M.; Yeola, Suresh N.;Reddy, G. R.; Mamett, Lawrence J.; Blair, Ian A.; Vanderbilt University School of MedicineHPLC/ESIIMS May Be The Technique of Choice for the Analysis of Certain DNA Adducts.; Yen, Ten-Yang;Gueorgieva, Nadia; Scheller, Nova; Holt, Sharon; Swenberg, James A.; *Charles, M. Judith; Dept. Environ. ScL &Eng., University of North Carolina at Chapel HillQuantitation of endogenous ethenoguanine by GCIECNCIIHRMS; *Scheller, Nova; Ranasinghe, Asoka; Yen, TenYang; Gueorguieva, Nadia; Swenberg, James; University of North Carolina at Chapel HillLunch Break, Workshops, PostersAssessment of DNA Oxidative Damage by Quantification of2-Methylglycerate from Thymidine Glycol; Naritsin,Dmitry; *Markey, Sanford P.; National Institute of Mental Health, BethesdaDetection of DNA Adducts by Electron Capture-MS; *Giese, R.; Nairn, A.; Abushamaa, A.; Pillai, S.; *Samson, L. 12; Northeastem University and Harvard School of Public Health

382 44TH ASMS CONFERENCE ON MASS SPECTROMETRY

WOF 5:10 Application of Capillary Separation Methods Coupled to MS for the Analysis of DNA; ·Vouros, Paul; Rindgen,Diane; BlII1)', John; Ding, Jianmei; The Barnett Institute, Northeastern University, Boston, MA

WOF 5:30 Development of MALDI- and ES-FTICR for the Characterization of DNA Adducts; *Hettich, Robert; Stemmler,Elizabeth; Tang, Liang; Buchanan, Michelle; Hurst, Gregory; Oak Ridge National Laboratory

THURSDAY ORAL SESSIONS

Thursday

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Thursday

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PLENARY LECTURE Prehistoric Cave Art at Vallon, Jean Clottes, French Ministry ofCuiture

FUNDAMENTALS OF ELECTROSPRAY, K. Ht: Michael Siu, presiding

New Developments in Understanding and Exploiting Electrospray Ionization; ·Smith, Richard D.; Tang, Keqi;Harms, Amy c.; Hofstadler, Steven A.; Anderson, Gordon A.; Udseth, Harold R.; Rockwood, Alan L.; Wu, Qinyuan;Pacific Northwest National Laboratory, Richland WAFractionation during evaporation ofES droplets; ·Fenn, John B.; Kiselev, Pavel; Rosell, Joan; VirginiaCommonwealth University, Richmond, Virginia 23284-2006 FThe Electrolytic nature of Elec:trospray; ·Van Berkel, Gary ; Zhou, Feimeng; Aronson, Joseph; Oak Ridge NationalLaboratoryBreakA Novel Three-Electrode System for Rapid Electrochemistry / Electrospray Mass Spectrometry; ·Cole, RichardB.; Lu, Wenzhe; Xu, Xiaoming; Department of Chemistry, University of New Orleans, New Orleans, LA 70148Ion mobility/mass spectrometric investigation of electrospray ions; ·Guevremont, Roger; Siu, K.W. Michael; Ding,Luyi; Inst. Nat. Measurement Stds., National Research Council of Canada, OttawaQuantitative Characteristics and Matrix Effects of Electrospray Mass Spectrometry; ·Ho, Zhanying Stacy; Shou,Zhenyu; Browner, Richard F.; School of Chem. & Biochem. ,Georgia Tech, Atlanta, GA 30332-0400Lunch Break, Workshops, PostersProtein Charge Distribution Studies - From Droplet in Air to Ion in Vacuum; *Thomson, Bruce; Sciex, Concord,CanadaAssessment of hydrogen bonding contributions in a gas phase protein by mass spectrometry.; ·Hunter, Christie L.;Mauk, A Grant; Douglas, Don J.; Dept. of Biochemistry, University of British Columbia, Vancouver, CanadaOn the origin of spray current pulsations in ES MS; Juraschek, Reinhard; Paulig, Rolf; Bohmer, Martin; ·Rtillgen,Franz W.; Inst. of Physical Chemistry, University ofBonnNew Electrospray Souce: Low Pressure Electrospray; ·Sheehan, Edward; Willoughby, Ross; Chem-Space Associates

MASS SPECTROMETRIC CHARACTERIZATION OF SYNTHETIC POLYMERS,Kevin Owens, presiding

MALDI-MS of Polymeric Materials; ·Kassis, Camille M.; Belu, Anna M.; DeSimone, Joseph M.; Linton, Richard W.;Lange, Gary W.; Friedman, Robert M.; University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290Thin Film MALDI Matrix Loading for Water Insoluble Compounds; *Milberg, Richard; University of Illinois,School of Chemical Sciences, Urbana, ILAnalysis of Low-Molecular Weight Polymer Blends by MALD/I Time-of-Flight Mass Spectrometry; *Hanton,Scott D.; Parees, David M.; Willcox, Dale A.; Goldschmidt, Robert; Owens, Kevin G.;; Air Products & Chemicals, Inc.,Allentown, PA 18195Polymer Analysis by MALDI - Rapid Molecular Weight and Chemical Modification Data; Wu, Kuang Jen;·Odom, Robert; Charles Evans & AssociatesBreakThe use ofMALDI in the characterisation of polymers with broad molecular weight distributions.; *Scrivens, Jim;Yates, Hilary; Jackson, Tony; Rumbelow, Steve; Fawcett, Joanne; Critchley, Glen; Deery, Michael; Jennings, Keith; ICIResearch CentreCharacterization of Synthetic Polymers by FT-ICR Mass Spectrometry; ·Pitsenberger, Cynthia C.; Danis, Paul 0.;Amster, 1.Jonathan; The University of GeorgiaFTICR-MS characterisation of (co-)polymers; *Heeren, Ron M.A. ; O'Connor, Peter B.; Duursma, Marc C; vanRooij, Gerard J.; van der Hage, Erik R.E. ; de Koster, Chris G. ; Boon, Jaap J.; FOM-Institute for Atomic and Molecularphysics, Amsterdam, The NetherlandsLunch Break, Workshops, PostersTandem Electrospray MS for Assessment of Copolymer Composition; ·Cook, Kelsey; Tuinman, AI; Haddix,Martin; Bennett, Kevin; Johnson, Jererni; University ofTennessee-KnoxviiteCoupling Gel Permeation Chromatography to MALDI Mass Spectrometry; *Fei, Xun; Murray, Kermit; EmoryUniversity, AtlantaMS characterisation of fresh and aged natural and synthetic varnishes used for paintings.; *Boon, Jaap J.; van denBerg, Klaas Jan; van der Hage, Erik R.E.; van der Doelen, Gisela A; O'Connor, Peter B.; Heeren, Ron M.A. ; de la Rie,Rene; FOM Intitute for Atomic and Molecular PhysisPrimary Thermal Degradation Mechanisms in Polyimides; ·Grayson, Michael; McDonnell Douglas Corporation


Thursday

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CELLULAR RECOGNITION AND SIGNAL TRANSDUCTION, Mark F. Bean, presiding

Investigation ofT-Cell Receptor Induced Signal Transduction Pathways Using Electrospray MS; *Aebersold, R.;Figeys, D.; Gu, M; Ducret, A; van Oostveen, I.; Bures, E. J.; Wange, R. L.; Samelson, L. E.; University of Washington,SeattleUnderstanding the Role of Protein Phosphorylation in Signal Transduction with the aid of MS; *Ann8O, Roland;Huddleston, Micheal; Carr, Steven; SmithKline Beecham PharmaceuticalsPSD Sequencing of Novel Invertebrate Gonadotropin Releasing Hormone Peptides from Tunicate; *Craig, AG.;Fischer, W.H.; Powell, J.F.F.; Reska-Skinner, S.M.; Park, M.; Rivier, J.E.; Sherwood, N.M.; The Salk Institute, La JollaBreakMonitoring Changes in Calcium-Induced Conformational Changes in Recoverin by ESI-MS; *Johnson, Richard;Neubert, Thomas; Walsh, Kenneth; Hurley, James; Department of Biochemistry, University of Washington, Seattle, WASequencing MHC Class I Kb Peptides Isolated from Mouse EL-4 Cells by Membrane PC-CE-MS(MS);*Tomlinson, Andy 1.;Jameson, Stephen; Naylor, Stephen; Mayo ClinicIdentification of Novel Sites of Phosphorylation of ScglO, A Neuronal Homologue of Stathmin; *Kassel, Daniel B.;Grenningloh, Gabriele; DiPaolo, Gilbert; Antonsson, Bruno; CombiChem, Inc., 9050 Camino Santa Fe, San Diego, CA92121Lunch Break, Workshops, PostersStructural Characterization of Non-Peptide Antigens: Is Presentation Paradigm Different?; *Reinhold, Vernon N.;Reinhold, Bruce B.; Porcelli, Steven A; Moody, Branch; Brenner, Michael B.; Boston University Medical School,Boston, MA 021 18Accurate Peptide Sequencing for Cloning and Homology Searching; Wilm, Matthias; Shevchenko, Andrej; *Mann,Matthias; European Molecular Biology Laboratory (EMBL)ESI-MS evaulation of the post-translation modifications to histones upon induction of apoptosis; *Lipton, Mary S.Weir; Thrall, Brian D.; Horan, R. Clinton; Springer, David L.; Edmonds, Charles G.; Pacific Northwest National LabProtein Identification with Tandem Mass Spectrometry and SEQUEST; *Yates, John R.; McCormack, Ashley L.;Eng, Jimmy K.; Schieltz, David M.; University of Washington, Seattle, WA

FAST SEPARATIONSIMASS SPECTROMETRY, Jack Holland, presiding

Coupling Matrix Assisted Laser Desorption Ionization Mass Spectrometry to Liquid Separations; *Murray,Kermit; Emory University, AtlantaOn-line High Speed Countercurrent Chromatography / ESIMS in Natural Product Chemistry; *Kong, Zhengrong;Rinehart, Kenneth; Milberg, Richard; School of Chemical Sciences, University of Illinois at Urbana-ChampaignNovel Strategies For The Coupling Of Capillary Electrochromatography With Mass Spectrometry; *Lane, Steve;Boughttlower, Robert; Paterson, Clare; Underwood, Tim; Morris, Michael; GlaxoWellcome, Gunnels Wood Road,Stevenage, Hertfordshire, SGI 2NY, UKBreakAdvances in High-Speed Gas Chromatography; *Sacks, Richard; University of MichiganHigh Speed, High Throughput GC/MS Using Time-of-Flight Mass Spectrometry with Time Array Detection;*Gardner, Ben; Holland, John; Michigan State UniversityLunch Break, Workshops, PostersFast GC and comprehensive 2DGC coupled to HRMS and TOFMS for environmental toxicant analysis; *Barr,John R.; Green, Vaughn; Grainger, James; Patterson, Donald G., Jr.; Holland, Jack; Gardner, Ben; Beaudry, Randy;Centers for Disease Control and PreventionOn-line Detection of Fast Chromatographic Events by Electrospray Ionization Time--of-Flight MS; *Gulcicek, ErolE.; Andrien, 8.; Banks, J. F.; Boyle, J. G.; Dresch, T.; Haren, P.; Whitehouse, C. M.; Analytica of Branford, Inc.Some Observed Phenomena of Linear Quadrupoles under Fast GC/MS Conditions; *Grimm, Casey C.; Lloyd,Steven W.; Southern Regional Research Center, USDA-ARS, New Orleans, LACombatibility of Fast GC with TOFMS: How Fast Can We Go?; *Parry, Ritchard; Artaev, Viatcheslav B.; McNitt,Kevin; Schmitz, Dermis; Phinney, Mary Jane; Mitchell, Joel; LECO Corporation, SI. Joseph, MI

FOURIER TRANSFORM MASS SPECTROMETRY, Evan Williams, presiding

Electrospray/FTICR SORI and WD Exchange Studies of Isolated Gas-Phase Protein Conformers; Bol8Oo5, B.J.;Stevenson, E.; Arkin, c.R.; *Laude, D.A; The University of Texas at AustinStructural Analysis of Polysaccharides and Peptides by MALDI FT-ICR MS; *Solouki, Touradj; Reinhold, Bruce,8.; Costello, Catherine E.; O'Malley, Matthew; Guan, Shenheng; Marshall, Alan, G.; National High Magnetic Field Lab,Florida State Univ., Tallahassee FLA Top Down Approach to Sequence Refinement of Large Proteins.; *Kelleher, Neil; Fridriksson, Einar; Valaskovic,Gary; Aaserud, David; Guan, Ziqiang; McLafferty, Fred; Cornell University, Ithaca, NYBlackbody Infrared Radiative Dissociation: From Dissociation Energetics to Structural Elucidation; *Price,William; Schnier, Paul; Williams, Evan; University of California, BerkeleyBreakNon-destructive, broad-band FT detection using de dipolar excitation in a quadrupole ion trap; *Cooks, R. G.;Soni, M.; Frankevich, V.; Nappi, M.; Bui, H.; Santini, R. E.; Amy, J. W.; Purdue UniversityOptimization of ion trapping and mass measurement in FT-ICR mass spectrometry; Bluhm, Brian; *GiIIig, Kent;Russell, David; Texas A&M University College Station

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ThOF 5:10

ThOF 5:30


Characterization of an Electrostatic Ion Guide for Transfer of Electrosprayed Ions Into an FTICa MS;*Buchanan, Michel1e; Hettich, Robert; Tang, Liang; Oak Ridge National Laboratory, Oak Ridge, TN 37931·6365Lunch Break, Workshops, PostersLD-FTMS Study of Air Oxidation of Self-Assembled Monolayers on Gold; *Wilkins, Charles L.; Scott, JiII R.; Yao,Jie; Fritsch,lngrid; Everett, Russel1 W.; University of California, RiversideAnalysis ofFTMS Signal Waveforms for Multi-electrode Detection; *Nikolaev, Eugene; Rakov, Sergey, Futrell,Jean; The Institute for Energy Problems of Chemical Physics, Moscow, RussiaCharacterization of ESI-FTICR Performance at Low Magnetic Fields; *Gorshkov, Michael V.; Wu, Qinyuan;Udseth, Harold R.; Anderson, Gordon A.; Smith, Richard D.; Pacific Northwest National LaboratoryAccurate Mass Measurements By Using Multiple Ionization Techniques Simultaneously with FT/MS.; *Castoro,John; Winger, Brian; FTIMS, Inc., 6416 Schroeder Rd., Madison WI, 53711-2424.

ENVIRONMENTAL MASS SPECTROMETRY, Kim Prather, presiding

Real-Time Characterization of Individual Particle in Ambient Aerosols in Riverside, California; *Noble,Christopher; Prather, Kirnberly; University of California, RiversideSingle Particle Analysis by On-line Bipolar Laser Mass Spectrometry and Multivariate Data Analysis; Hinz,Klaus-Peter; Drews, Frank; Lange, Ronald; Kaufmann, Rairnund; *Spengler, Bernhard; Institute of Laser Medicine,University of Duesseldorf, GermanyOn-Line Analysis of Aqueous Aerosols; *Neubauer, Kenneth; Johnston, Murray; Wexler, Anthony; University ofDelaware Newark, DE 19716Instrumentation for Tropospheric Aerosol Characterization; *Shi, Zhouzheng; Young, Steve; Becker, Chris;Coggiola, Mike; Wollnik, Hermann; SRI International Menlo ParkBreakReal-Time MS/MS of Organic Airborne Particulates; *Reilly, Peter; Gieray, Rainer; Yang, Mo; Whitten, William;Ramsey, Michael; Oak Ridge National Laboratory, Oak Ridge, TNFate Studies of 3,3'-Dichlorobenzidine in Contaminated Lake Sediment by a Small Low-Field FTIICR MS.;*Nyman, Marianne C.; Perez, James; Nyman, Arto K.; Blatchley Ill, Ernest R.; Kenttamaa, Hilkka I.; Purdue University,West Lafayette, INOptimization of Trace Analysis by Ion Trap MS/MS; *Lynn, Jr., Bert C.;; Mississippi State University.Lunch Break, Workshops, PostersThe Study ofPAH Transformations on Single Micrometer-Sized Particles Using TOF-SIMS; *Fister, Thomas;Strossman, Greg; Summers, Stacie; Linton, Richard; Odom, Robert;; Charles Evans & AssociatesStatic SIMS Studies of Organophosphate Adsorption on Metal Oxides; *Ingram, Jani; Groenewold, Gary; Wright,Randy; Appelhans, Anthony; Idaho National Engineering Laboratory, Idaho Falls, IDOn-Line and Near-Real Time of GC/MS Based Analytical Techniques in Field and Process; *McClennen, WilIiam;Cole, Paul; Meuzelaar, Henk; Arnold, NeH; Center for Micro Analysis, University of Utah, Salt Lake City, UtahCapillary Electrophoresis/Electrospray/Mass Spectrometry of the Herbicides Paraquat and Diquat; Xinbei, Song;*Budde, WilIiam L.; U. S. Environmental Protection Agency, Cincinnati, OH 45268

MONDAY POSTERS

HISTORY OF MASS SPECTROMETRY INSTRUMENTATION

Abstracts are arranged alphabetically by first author

MPA The State ofthe Art of Time-of-flight Mass Spectrometer in 1958; *Grayson, Michael; McDonnell Douglas Corporation, StLouis MO 63166

MPA Evolution of the Consolidated Engineering Corporation 21-110 Double Focusing Mass Spectrometer; *Grigsby, RonaldD.; BDM-Oklahoma, Inc./NIPER, Bartlesville, Oklahoma

MPA Small Mass Spectrometers manufactured by C.E.C.; *Judson, Charles; Universty of Kansas, Lawrence, KS, 66045MPA A Classic Mass Spectrometer (CEC 21-1I0B) Modified for Continued Yough, Vitality and Productivity; *Ramaley,

Louis; **Jamieson, W. David; Department of Chemistry, Dalhousie University, Halifax, NS, Canada, B3H 413MPA The Literature of Mass Spedrometry; *Sparkman, O. David; O. David Sparkman & Associates

ION SOURCE AND MS INSTRUMENTATION

Abstracts are arranged alphabetically by first author

MPB The Design ora New Direct Probe Inlet for a Mass Spectrometer; *Baker, Christopher; Manos, John; Scientific InstrumentServices, Inc. Ringoes, NJ .

MPB Application of SIMION 6.0 to Filament Design for Mass Spectrometer Ionization Sources.; *Baker, Christopher W.;Colby, Steven M.; Manura, John; Scientific Instrument Services, Inc. Ringoes, NJ

MPB A computer simulation ofthe current distribution in an electron multiplier.; *Batey, Jonathan; Liezers, Martin; VGElemental

MPB Modification of an HP 5972 MSD for use in Direct Sampling of Volatile Organic Compounds in Water; *Bauer, Scott;Griffin, Timothy; Bauer, Janice; MIMS Technology Incorporated, Palm Bay, Florida

MPB Measuring Charge on Individual Electrospray Ions (z > 425); *Benner, W. Henry; Fuerstenau, Stephen D.; LawrenceBerkeley National Laboratory

MPB An Improved Multiple ADC Transient Recorder Data System for MALDI MS; Carroll, James; Chen, Xiangjun; *Beavis,Ronald; New York University Medical School


MPB Ion Imaging Using a Charge Injection Device (CID) Detector; ·Christopher, Steven J.; Marcus, R. Kenneth; ClemsonUniversity, Department of Chemistry, Clemson, SC 29634-1905

MPB A Conceptual Pulsed Heavy Ion Gun for MeV Particles based on Neutron Generator Technology; .Fries, David;O'Malley, Rebecca; ··Browning, J.F.; U. South Florida Marine Science Dept & Chemistry Dept, Tampa FL

MPB A new electrospray source designed for an HP-5985 ES·MS; ·Kiesel, Jennifer R.; Habibi-Goudarzi, Sohrab; Deppennan,Kevin L.; Duffin, Kevin L.; Monsanto Corporate Research, Monsanto Co., St. Louis, MO 63198

MPB The Development of an Enhanced Microchannel Plate Detector for Time-of-Flight Mass Spectrometry; ·Laprade,Bruce; Fuchs, Wolfram; Lincoln, Brian; Galileo Electro-Optics, Galileo Park, PO Box 550, Sturbridge, MA 01566

MPB Tunable Energy Electron Monochromator Interface to a Sector Instrument; ·Laramee, James; Cody, Robert; Deinzer,Max; Dept. of Agricultural Chemistry, Oregon State University, Corvallis, OR

MPB Atmospheric Pressure Microwave Induced Plasma as an Ionization Source for Mass Spec:trometry; ·Moini, Mehdi;University of Texas at Austin, Austin

MPB Comparison of El and MAD ionization for exact mass measurement.; ·Mousselmal, Moussa; Faubert, Denis; Evans,Michael J.; Bertrand, Michel J.; University of Montreal, Montreal

MPB Performance of a new needle configuration In a Finnlgan electrospray ion source; .Musser, Steven; Sphon, James;Instrumentation and Biophysics Branch, CFSAN, FDA, Washington, DC 20204

MPB Soft Ionization In the Quadrupole Ion Trap for Chemical Type Analysis; ·Roussis, S.G.; Cameron, AS.; Imperial Oil,Samia Research Centre, Samia, Ontario, Canada, N7T 7MI

MPB A New Simple and Divers Interface for Mlcrocolumn Separation API-MS; ·Sjoberg, Per J. R.; Markides, Karin E.; Dept.of Analytical Chemistry, Uppsala University

MPB An Electron Multiplier With On-Board Preamplifier For Detecting Ion Signals Ranging Over Nine Orders; ·Stresau,Richard W.; Hunter, Kevin L.; ETP Electron Multipliers, 3 I Hope St., Ennington, Australia 2115

MPB Accurate mass measurement at low resoution by using electrospray-MS on a quadrupole instrument.; ·Tyler, AndrewN.; Clayton, Eddie; Green, Brian N.; Harvard Chemistry Department, Cambridge, MA

MPB Performance of a Submicroliter Per Minute Electrospray Probe; ·Whitehouse, Craig; Banks, J. Fred; Whitehouse, Glenn;Analytica of Branford Inc.

MPB Design and Performance of a Mlcroscale ESI Source for High Resolution Measurements; ·Wulser, Kurt; Smith, DavidL.; Department of Chemistry, University of Nebraska, Lincoln, NE 68588-0304

MPB Liquid Ionization Mass Spectrometry of Clusters Containing Water in Gas and Liquid Phases; ·Yaming, Li;"Takashi, Tashiro; Kotaro, Hama; Masahiko, Tsuchiya; Yokohama National University, Tokiwadai, Hodogayaku,Yokohama, 240 Japan

MPB Laser Droplet Mass Spectrometry; ·Zhou, Jie; Lee, Terry; ··Mahoney, John; Beckman Research Institute of the City ofHope, Duarte, CA 910 10

FUNDAMENTAL STUDIESAbstracts are arranged alphabetically by first author

MPC Ab Initio Calculations of Proton Affinities, Ionization Potentials, and Electron Affinities of PAHs; ·Betowski, Leon;Aue, Donald; Beeloo, Edward; U.S. Environmental Protection Agency, Las Vegas, NV 89193

MPC Entropy Effects Upon the Dissociation of Metal Ion Bound Dimers of Biomolecules; ·Cerda, BIas A; Wesdemiotis,Chrys; Chemistry Department, The University of Akron, Akron Ohio 44325-3601

MPC A PMO theory of ion-molecule collision and electron-transfer rates; ·Dougherty, Ralph; Dept of Chemistry, Florida StateUniversity, Tallahassee FL 32306-3006

MPC Ionization Energies and CID Fragmentation Patterns of Distorted Porphyrins; ·Ferguson, James A.; Yost, Richard A(I); Quirke, J. Martin E (2); University of Florida Chemistry Department, Gainesville, FL

MPC S(OH)2 as a Stable Oxidized Sulfur Intermediate by Neutralization-Reionization Mass Spectrometry; • Frank, Aaron;Sadilek, Martin; Ferrier, Jordan; Turecek, Frantisek; University of Washington

MPC S02H as a Stable Oxidized Sulfur Intermediate by Neutralization-Reionization Mass Spectrometry; ·Frank, Aaron;Sadilek, Martin; Ferrier, Jordan; Turecek, Frantisek; University of Washington

MPC Diagnostics of Microwave Plasmas of C2H4: Li+ ion attachment mass spectrometry; ·Fujii, Toshihiro; Kim, Ho Seob;"Kishi, Hiroshi; National Institute for Environmental Studies, Tsukuba, Ibaraki 305, JAPAN

MPC The mass spectrometric detection of very large clusters/polymers in molecular beams; ·Greene, Frank; Mid-ContinentResearch, Lake Quivira, KS

MPC Antiaromatic Ions: A Flowing Afterglow Study; Han, Sangdon; Arrowood, Tina; Sathers, Sandra; Eckert-Maksic, Mirjana;• Kass, Steven; University of Minnesota

MPC Structures, Bonding and Reactions of2c-3e Sulfur-Sulfur, Halogen-Halogen and Sulfur-Halogen Systems; ·IlIies,Andreas; James, Mary A.; Nichols, Linda; Auburn University, Auburn

MPC Energetics and higher order structure of multiply protonated peptides in the gas phase; ·Kaltashov, Igor; Fenselau,Catherine; Dept. of Chem., Univ. of Maryland Baltimore County, Baltimore, MD 21228

MPC Ionization of Some Aliphatic Alcohol Molecules with Kinetic Energy on Surfaces; ·Kishi, Hiroshi; "Fujii, Toshihiro;Oyarna National College of Technology, Oyama, Tochigi 323, JAPAN

MPC Experimental and Computational Studies of Double Ionization of Alkynes.; ·Martin, Rachel L; Harris, Frank M;Andrews, Stuart R; Parry, David E; Mass Spectrometry Research Unit, University of Wales Swansea, Swansea, UK.

MPC What Does TPEPICO Say About Ionized Methyl Acetate ?; Mazyar, Oleg; ·Mayer, Paul M.; Baer, Tomas; ChemistryDept., University of North Carolina at Chapel Hill, Chapel Hill

MPC The Unimolecular Chemistry of Ionized B(OCH3)3; ·Mayer, Paul M.; Baer, Tomas; Chemistry Department, University ofNorth Carolina, Chapel Hill, N.C.


MPC Gas Phase Acidities Using Density Functional Theory: Is It Reliable? Is It Cheap?; Merrill, Grant; *Kass, Steven:University of Minnesota

MPC Cation-Ether Complexes in the Gas Phase: Bond Dissociation Energies and Equilibrium Structures; *More, MicheUe;G1endening, Eric; Hill, Sue; Ray, Doug; Feller, Dave; Arrnentrout, P. B.; Chemistry Department, University of Utah, Salt LakeCity

MPC Comparison of Nanosecond and Femtosecond Multiphoton Ionization Processes; *Moritz, Fritz; Heinicke, Ralf; Grun,Carsten; Grotemeyer, Jurgen; Insttitut flIr Physikalische Chemie, Universitllt WUrzburg

MPC Determination of Metal Ion Binding Affinities of the DNA Bases by Guided Ion Beam Mass Spectrometry.; *Rodgers,M. T.; Arrnentrout, P. B.; University of Utah, Salt Lake City

MPC Metastable H3S by Neutralization-Reionization Mass Spectrometry; *Sadilek , Martin; Turecek, Frantisek; University ofWashington, Seattle

MPC Neutralization-Photoionization Mass Spectrometry for the Study of Hypervalent Radicals; *Sadilek , Martin; Turecek,Frantisek; University of Washington, Seattle

MPC Ab Initio QCISD(T) Calculations for the Ground Potential Energy Surface of He3+; Satterwhite, M. F.; *Gellene,Gregory; Dept. of Chem. & Biochem. Texas Tech Univ., Lubbock, Tx 79409-1061

MPC Ab Initio Studies of Polyiodide Anions; Sharp, Stephanie; *Gellene, Gregory; Dept. of Chem & Biochem., Texas TechUniversity, Lubbock, TX 79409-1061

MPC The inOuences of ion activation and thermalization effects on reaction rate constant in the ITMS.; Steiner, Valeric:Liere, Philippe; **Jennings, Keith; March, Raymond; Tabet , Jean-Claude; Universite P. et M. Curie

MPC Proton Affinity and Association Thermochemisty of Cyclic Anhydrides; *Szulejko, Jan; McMahon, Terry; Department ofChemistry, University of Waterloo, Waterloo, Ontario, CANADA

MPC Combined HPMS, Metastable Ion and Collision Activation Study ofOrgano-Silyl Cations and Adducts; *Szulejko, Jan;**Hop, Cornelis; Saulys, Dovas; Gaines, Donald; McMahon, Terry; Department of Chemistry, University of Waterloo,Waterloo, Ontario, Canada

MPC The Gas Phase Ion/Molecule Chemistry of Distonic Radical Cations revealed by FT-ICR; *Troude, Valerie; Audier,Henri; Leblanc, Danielle; Mourgues, Philippe; DCMR, CNRS URA 1307, Ecole Polytechnique, F-91128 PALAISEAU

MPC Thermochemical Properties of bifunctionallinear and cyclic products; *Troude, Valerie; Audier, Henri; Bouchoux, Guy;**McMahon, Terrance B.; Szulejko, Jan E.; DCMR, CNRS URA 1307, Ecole Poly technique, F-91128 PALAISEAU

MPC Unimolecular reaction dynamics from kinetic energy release distributions; Urbain, Pascale; *Leyh, Bernard; Rernacle,Fran oise; Lorquet, Jean-Claude; Department of Chemistry, Li ge University, B.4000 SART-T1LMAN

MPC Production of Molecular Ar Ions in Associative Ionization at a Pressure of Several Torr; *Vinogradov, P. S.; Borisenko,D. M.; Veretennikov, I. N.; Institute of Energy Problems of Chemical Physics, Russian Academy ofSci.

MPC Collision-induced emission spectroscopy ofsolitary ions; *Wesdemiotis, Chrys; Wiedmann, Fred A.; Wu, Jianglin;Chemistry Department, The University of Akron, Akron, Ohio, 44325-3601

MPC Measurements ofthe Lifetimes orIon-Molecule Collision Complexes; *Williamson, D.H.; Knighton, W.B.; Grimsrud,E.P.; Montana State University Bozeman, MT

MPC Hypervalent Ammonium Radicals by Neutralization-Reionization of Protonated DABCO; *Wolken, JiIl; Nguyen, VietQ.; Turecek, Frantisek; University of Washington

MPC Agostic and steric effects on atomic and polyatomic cation affinities of pyridines; *Wong, Philip; Ma, Shuguang; Cooks,Graham; Eberlin, Marcos; Guzzo, Fabio; Purdue University

MPC Inverted region behavior'in gas phase electron-transfer reactions; *Xu, Ming; Li, Weiqun; Marshall, Alan; Guan,Shenheng; Dougherty, Ralph; Dept of Chemistry, Florida State University, Tallahassee FL 30306-3006

TRAPPED IONS

Abstracts arearranged alphabetically byfirst authorMPD Evaluation of Transition Metal Ion and Ammonium Ion Complexation by Pharmaceuticals in a QITMS; *Alvarez,

Erwin; Vartanian, Victor; Brodbelt, Jennifer; The University of Texas at Austin, Austin, TexasMPD Size-Selective Collision Activated Dissociation of Transition Metal IonlPolyether Complexes in a QIT; *Alvarez, Erwin

J.; Wu, Hui-Fen; Brodbelt, Jennifer S.; The University ofTexas at Austin, Austin, TexasMPD Increased Sensitivity for Quadrupole Ion Traps by Rapid Removal ofRF; *DeGnore, Jon P.; Yost, Richard A.; Jones, Jon

A.; University of Florida, GainesvilleMPD High Kinetic Energy CIMS in the Quadrupole Ion Trap - Effect of Axial Modulation; *Dorey, R. Cameron; Dobbs,

Sheri; University of Central Arkansas, Conway, ARMPD Fragmentation of Sodium Cationized Molecules of Cyclic Peptides in MALDIIQuadrupole Ion Trap MS.; *Doroshenko,

Vladimir M.; Cotter, Robert J.; Pharmacology, Johns Hopkins University Medical School, Baltimore MDMPD Description and characteristics ora novel FT-Ion Trap Mass Spectrometer; *Frankevich, Vladimir; Soni, Manish; Nappi,

Mario; Cooks, R. Graham; Santini, Robert E; Amy, Jon W; Purdue University, West Lafayette, INMPD The effect of ion trap field parameters on the ion/molecule reactions of o-dichlorobenzene; Franklin, Tony M.; *Todd,

John FJ.; Chemistry Department, University of Kent ,Canterbury, Kent, cn 7NH, UK.MPD Using an Ion Trap for LCIMS Analysis of Benzodiazepines; *Goodley, Paul C.; Fjeldsted, John C.; Hewlett-Packard Co.,

1601 California Ave., Palo Alto, CA 94304MPD Practical Considerations for Successful API-LCIMS of Pharmaceuticals Using a Quadrupole Ion Trap; *Goodley, Paul

C.; Fjeldsted, John C.; Hewlett-Packard Co., 1601 California Ave., Palo Alto, CA 94304MPD Progress in the Development of a Transportable QUlSTORlreTOF-MS for Air Monitoring; *Grace, Louis I.; Chambers,

David M.; Thomas, Stan W.; Andresen, Brian D.; Lawrence Liverrnore National Laboratory


MPD Analysis of Compounds of Pharmaceutical Interest by Solid Phase Microextraction and Ion Trap GC/MS; *Hall, BradJ.; Brodbelt, Jennifer S.; The University of Texas at Austin, Department of Chemistry, Austin, Texas

MPD Negative Ion Studies with a Conventional Quadrupole Ion Trap Mass Spectrometer; Jean-Charles, Mathurin; Sebastien,Gregoire; *Jean-Claude, Tabet; **Raymond E., March; Universite Pierre et Marie Curie (Paris)

MPD Comparison of quadrupole and ion trap GC-MS-MS for the detection of muramic acid in airborne dust; *Krahmer,Mark; Fox, Alvin; Fox, Karen; University of South Carolina, School of Medicine, Columbia, South Carolina

MPD Analytical Performance of an Ion Trap Mass Spectrometer Using Air as the Buffer Gas; *Lammert, Stephen A.;Merriweather, Roosevelt; Wise, Marcus B.; Oak Ridge National Laboratory

MPD A Comparison of Experimental Procedures for Resonamt Excitation in an Ion Trap Mass Spectrometer; *Lausevic,Mila; Lausevic, Zoran; March, Raymond E.; Department of Chemistry, Trent University, Peterborough, ON, Canada K9J 7B8

MPD Positive Ions and Negative Ions of Toxaphene Formed in an Ion Trap; *Lausevic, Mila; Splendore, Maurizio; Jiang,Xuewu; March, Raymond E.; Department of Chemistry, Trent University, Peterborough, ON, Canada K9J 7B8

MPD Effects of Rapid Change in Trapping Parameter Due to Reaction; *Lausevic, Zoran; Londry, Frank A; March, RaymondE.; Department of Chemistry, Trent University, Peterborough, ON, Canada K9J 7B8

MPD Ion Coupling Effects and Mass Shifts in Ion Trap Mass Spectrometry; Mo, Wenjun; *Todd, John J F ; ChemistryDepartment, University of Kent, Canterbury, Kent CT2 7NH, UK

MPD Structure Elucidation by MS/MS/MS on a Hybrid Tandem Mass Spectrometer; *Muenster, Helmut; Huels, Wilfried;Schroeder, Emst; Finnigan MAT GmbH, D-28197 Bremen, Germany

MPD Three-Dimensional Representations of Ion Motion in the Quadrupole Ion Trap; *Nappi , Mario; Cleven, Curtis D.; Soni,Manish H.; Bui, Huy A.; Weil, Carsten; Cooks, R. Graham; Purdue University, West Lafayette IN 47907

MPD Characterization of Photographic Couplers using an API-Ion Trap Mass Spectrometer; *Nichols, WiIliam; **HabibiGoudarzi, Sohrab; Henion, Jack; Eastman Kodak, Analytical Technology Division, Rochester, New York

MPD Tandem-in-time ion trap MS 11: Isotope dilution quantification ofamphetamines in human urine.; *Phinney, Curtis S.;Welch, Michael J.; National Institute of Standards and Technology, Gaithersburg, MD 20899-0001

MPD Frequency-Sweep Ion Trap Mass Spectrometry; *Price, John M.; Gorshkov, Michael V.; Barlow, Stephan E.; Ray,Douglas; Pacific Northwest National Laboratory, Richland, WA 99352

MPD Instrumental Development and Characterization of a Linear Ion Trap Time-of-Flight Mass Spectrometer; *Purves,Randy; Gabryelski, Wojciech; Li, Liang; University of Alberta, Edmonton

MPD Theoretical Study of The Ring Closure of 1,7-0ctadiyne, I-Octen-7-yne and 1,7-0ctadiene; *Robbins, Ronny; Jensen,James; Berg, Fred; U.S. Army, Aberdeen Proving Ground, Edgewood Area, APG, MD

MPD Sensitivity Improvement of NanoSPRAV-Ion Trap MS; *Schubert, Michael; Wang, Yang; Franzen, Jochen; BrukerFranzen Analytik GmbH, Fahrenheitstr. 4, D-28359 Bremen

MPD Self Chemical Ionization of Organophosphorus Esters in an Ion Trap; *Slivon, Laurence; Carleton, Linda; Dejarme,Lindy; Battelle Memorial Institute

MPD A Simulation Study of Resonant Excitation in a Stretched Ion Trap; *Splendore, Maurizio; March, Raymond.E.; Londry,Frank.A; Morrison, Richard.J.S.; **Perrier, Pierre; Andre, Jacques; Department of Chemistry, Trent University, Peterborough,ON, Canada, K9J7B8

MPD A Comparative Study of On-Axis and Asymptotic Ion Injection in the Quadrupole Ion Trap; Stephenson Jr., James L.;*Asano, Keiji G.; Goeringer, Douglas E.; Mcl.uckey, Scott A.; Oak Ridge National Laboratory, Oak Ridge, TN

MPD Instrumentation for the Reaction of Multiply Charged Cations with Singly Charged Anions in the QITMS; *StephensonJr., James L.; McLuckey, Scott A.; Oak Ridge National Laboratory, Oak Ridge, TN

MPD Application of SWIFT for Elucidation of Reaction Pathways in the Quadrupole Ion Trap; *Vartanian, Victor, H.; Shen,Jim; Brodbelt, Jennifer, S.; The University ofTexas at Austin

MPD Experimental Investigation of Space Charge Effects on Ion Distributions in a Quadrupole Ion Trap; *Ventura, M.C.;Laude, D.A.; The University of Texas at Austin

MPD Improvements to Electrospray-Ion Trap MS for the Detection of Drug Residues; *Voyksner, Robert; Lee, Heewon;Analytical & Chemical Sciences, Research Triangle Institute, RTP, NC 27709

MPD Comparison of mass resolution between resonance and non-linear resonance ejection at Oz=2/3; *Wang, Mingda; Wells,Gregs; Varian Chromatography System, 2700 Mitchell Dr, Walnut Creek, CA 94598

MPD Simulation Study Of Electrical Ion Cooling; *Weil, Carsten; Cleven, Curtis D.; Nappi, Mario; Cooks, R. Graham; PurdueUniversity, West Lafayette

MPD A TRAPTOF-Mass Spectrometer for Investigations ofUnimolecular Reactions.; Weickhardt, Christian; Wilhelm, Ulf;MUller, Matthias; *Grotemeyer, JUrgen; Institut fUr Physikalische Chemie, Universitllt WUrzburg

MPD Mass Scanning In An Asymmetrical Trapping Field; *Wells, Greg; Varian Chromatography Systems, Walnut Creek CAMPD Selective Cleavage of Peptide Bonds Using Ion/Molecule Reactions; *WiIliams, Tracie L.; Yost, Richard A; University of

Florida, Gainesville, FL

ENVIRONMENTAL ANALYSISAbstracts are arranged alphabetically by first author

MPE A Rapid Screening Technique for Identification of Spinosad Photolysis Products Using ESUMS/MS; *Balcer, Jesse L.;Brown, Stephen M.; Berard, David F.; DowElanco, Indianapolis, IN

MPE Quantitative Analysis of Quinclorac and Degradates by lonspray LC-MSIMS; *Bethem, Robert; Jordan, Jeannine;**McGown, Steven; ALTA Analytical Laboratory

MPE Structural Analysis of Algal Transformation Products Using LC/ESUMS; *Brum, Jeffrey; Hsu, Leo; Orvos, David;SmithKline Beecham Pharmaceuticals, King of Prussia, PA


MPE Trace Level Determination of Pesticides by On-Line Extraction and LC with APcI tandem MS.; *Hogenboom, Ariadne;Slobodnik, Jaroslav; Vreuls, Rene; **Rontree, John; van Baar, Ben; Niessen, Wilfried; Brinkman, Udo;

MPE Study of Oxidation Products of Dyes by Electrospray-Ion Trap Mass Spectrometry; *Lee, Heewon; Voyksner, Robert;Analytical & Chemical Sciences, Research Triangle Institute, RTP, NC 27709

MPE Quantitation of Soil Metabolites Utilizing Narrow Bore LC/MS/MS on Quadrupole Mass Spectrometers; *McGown,Steven; Delgado, Nelson; Werness, Steven; BASF Corporation, Research Triangle Park

MPE Determination of an Experimental Fungicide and Metabolites in Soil; *Perkins, John; Jiang, Jennifer; Henion , Jack;**Jordan, Jeannine; McGown, Steve; Advanced BioAnalytical Services, Inc., Ithaca

MPE Identification of Surfactants in Real Samples by HPLC-IS-MS and MS-MS; *Raffaelli, Andrea; Pucci, Sergio; Campolmi,Laura; Salvadori, Piero; Centro Studio CNR Macromolecole Stereordinate ed Otticamente Attive

MPE APCIIMS Analysis of Hydrolysis and Oxidation Products of the Chemcial Agent VX; *Rohrbaugh, Dermis; U.S. ArmyEdgewood RD&E Center, APG, MD 21010-5423

MPE Investigating the Metal Binding Properties of Dissolved Organics in the Environment Using LC/ESI-MS; **Ross,Andrew; *Ikonomou, Michael G.; Orians, Kristin; Institute of Ocean Sciences, Sidney BC, Canada

MPE The Analysis of Explosives Constituents and Metabolites using Electrospray and APCI LC/MS; *Schilling, Alexander;Hewlett Packard Co., Naperville, 1II

MPE Comparison of APCI and ESI - LC/MS for the Determination ofCarbamates; *Shoemaker, Jody A.; Behymer, ThomasD.; U.S. Environmental Protection Agency, Cincinnati

MPE APCI LC/MS Analysis of High Molecular Weight PAH Isolated from Complex Environmental Samples; *Smith,Richard W.; Marvin, Chris H.; McCarry, Brian E.; Department of Chemistry, McMaster University, Hamilton, ON, L8S 4MI,CANADA

MPE Qualitative and quantitative determination of aromatic sulfonates using capillary LC-MS; *Suter, Marc J.-F.; Riediker,Sonja; Giger, Waiter; Swiss Federal Institute for Environmental Science and Technology, EAWAG

MPE Pesticide Analysis Using Sonic Spray Ionization Mass Spectrometry; Yukiko, Hirabayashi; Atsumu, Hirabayashi;*Yasuaki, Takada; Minoru, Sakairi; Hideaki, Koizumi; Central Research Laboratory, Hitachi Ltd., Kokubunji, Tokyo 185,Japan

QAlQC AND PROCESS MONITORINGAbstracts are arranged alphabetically by first author

MPF The Application of Molecular Beam Mass Spectrometry to the Problem of Plastics Recycling; Elam, Carolyn; *Evans,Robert; Meglen, Robert; Tatsumoto, Kuniyasu; National Renewable Energy Laboratory (NREL), Golden, CO

MPF Identification of Pharmaceutical Particulate Contaminants by Pyrolysis MS using a DEI Probe; *Forbes, Robert A. ;Lilly Research Laboratories, EH Lilly and Company, Clinton, IN 47842

MPF On line MS to monitor a new process of mineralization of organic liquid nuclear waste.; *Franck, Rouppert; FrenchAtomic Energy Commission - Marcoule - France

MPF Spectral Resolution of Structural Hydrocarbons: A Process Mass Spectrometry Application; *Haddix, Martin; Cook,Kelsey; Bennett, Kevin; University ofTennessee-Knoxville

MPF Development of a MIMS method for on-line analysis of industrial waste waters and air emissions; **Honkanen, Tapio;*Ketola, Raimo; Mansikka, Timo; Kostiainen, Risto; Kotiaho, Tapio; Komppa, Veikko; Wickstrom, Kim; Vahervuori, Hilkka;VTT, Chemical Technology, r.o. Box 1401, FIN-02044 VTT, Finland

MPF Direct Sampling APIITOFMS for the Determintaion of Trace Impurities in High Purity Process Gases; *Lee, Edgar;Wu, Mingin; Lippert, Andrew; Cox, Lee; Lee, Milton; Sensar Corporation

MPF MBMS Study of A Premixed Fuel-Rich Ethylene Flame; *Luo, Fei; Yeh, Lisa I; Exxon Research and EngineeringCompany, Annandale, NJ 0880 I

MPF Study of Organic Matrix MIIMS using Alternative Membrane Materials; *Maden, Amy 1.; Ficarro, Scott B.; Hayward,Mark J.; American Cyanamid - Princeton, NJ

MPF Improving Detection Limits ofClenbuterol by Upgrading the HP 5970; *Roy, Laura; **Jehnsen, Chris; Graves, Peter;Hamerly, Thomas; Detector Technology, Inc., Sturbridge, MA

MPF The evaluation of a benctop API LC-MS system for the determination of impurities in pesticides; *Shushan, Bori;**Yves, Le Blanc; PE-Sciex, 71 Four Valley Drive, Concord (Ontario) L4K 4V8, Canada

MPF MBMS Studies of Thermal Decomposition and Catalytic Steam Reforming Reactions of Oxygenates; *Wang, Dingneng;**Montane, Daniel; Chornet, Esteban; National Renewable Energy Laboratory, Golden, Coloardo, USA

MPF Classifying analgesics by batch of origin using pyrolysis MS with pattern recognition; *Wilkes, Jon G.; Akbar, Safdar;Barry, Thomas L.; FDA, National Center for Toxicological Research, Jefferson, AR 72079-9502

MPF Characterization of degradates and process impurities in Merck products; *Yin, Winnie; Harmon, Paul; Reed, Robert;Tyrrell, R. Jeff; Merck & Co. Inc., West Point, PA

SEPARATIONSIMS TECHNIQUES - APPLICATIONSAbstracts are arranged alphabetically by first author

MPG SFC/ionspray-MS for the Analysis ofChiral Pharmaceuticals.; *Baker, Timothy R.; Pinkston, 1. David; Hentschel,Rosemary; Procter & Gamble Pharmaceuticals

MPG Determining the Site(s) of Protein-Inhibitor Complexes Through the Use of On-Line LCIESI-MS; *DeJohn, Dana; Loo,Joseph; Parke-Davis Pharmaceutical Research, Ann Arbor, MI

MPG Capillary ElectrochromatographylMass Spectrometry: Separation and Detection of DNA Adducts.; *Ding, Jianmei;Vouros, Paul; Bamen Institute, Northeastern University, Bonston, MA 02115


MPG The Direct Analysis of Fuels by Supercritical Fluid Chromatography / Mass Spectrometry; *Drinkwater, Donald; Chen,Evan; Nero, Vincent; Texaco R&D, PO Box 509, Beacon, NY 12508

MPG Chromatographic Peak Purity Determination Using LC/MS: A Practical Examination,; *Fisher, Dixie; Morgan, Daniel;Moseley Ill, M. Arthur; Whitlock, A. Luke; Glaxo Wellcome Inc., Research Triangle Park, North Carolina

MPG Characterization of Degradation Products of Beta-Lactam Antibiotics Using HPLC-MS; *Gao, Quanyin; **Freiha,Bassam; Biocraft Laboratories, Inc., 5000 Christopher Dr., Mexico, MO 65265

MPG Investigation of the HPLC electrochemical response of erythromycin by HPLC-ECD-APCIIMS analysis; *Hansen,Eugene B.; Luo, Wenhong; Churchwell, Mona I.; Thompson, Harold C.; Doerge, Daniel R.; National Center for ToxicologicalResearch

MPG Pharmaceutical Applications ofSFC/MS with Electrospray Ionization; *Hayes, Roger; Parke-Davis PharmaceuticalResearch, Division of Warner-Lambert Company

MPG Determination of Brevetoxin Distributions in Natural "Red Tide" Algae Blooms by LC-Electrospray-MS; *Hua,Yousheng; Lu, Wenzhe; Henry, Michael S.; Pierce, Richard H.; Cole, Richard 8.; Department of Chemistry, University ofNew Orleans, New Orleans, LA 70148

MPG Applications OfCEC/MS In The Pharmaceutical Industry; *Lane, Steve; Morris, Michael; Boughtflower, Robert;Paterson, Clare; Underwood, Tim; GlaxoWellcome, Gunnels Wood Road, Stevenage, Hertfordshire, SGI 2NY, UK

MPG Studies of Human Lens Beta-Crystallins by High-performance Liquid Chromatography / Mass Spectrometry; *Ma,Zhixiang; Smith, lean B.; Smith, David L.; Lampi, Kirsten; Department of Chemistry, University of Nebraska-Lincoln,Lincoln, NE 68588

MPG Evaluation of MAB as a selective Ion Source for Chromatography/Mass Spectrometry Techniques; *Mireault, Pascal;Faubert, Denis; Carrier, Alain; Mousselmal, Moussa; Bertrand, MJ.; University of Montreal

MPG Directly Coupled Packed Column SFC With APCI/MS; *Morgan, Daniel; Norwood, Daniel; Fisher, Dixie; Moseley Ill,M. Arthur; Glaxo Wellcome Inc., Research Triangle Park, NC 27709

MPG Optimizing Speed, Sensitivity and Resolution in LC/MS Analysis of Pharmaceuticals; *Nugent, Kerry; Stoney, Ken;**Mylchreest, lain; Wheeler, Kevin; Michrom BioResources, Inc.

MPG Improved response in Ions pray MS with packed-column SFC and SF-assisted nebulization; *Pinkston, 1. David; Baker,Timothy R.; The Procter & Gamble Company, Miami Valley Laboratories, Cincinnati, OH

MPG On-line LC-NMR-MS: a useful technique for obtaining the maximum information from mixtures; *Pullen, Frank;Swanson, Alistair; Newman, Michael; Burton, Keith; Pfizer Central Research UK

MPG The Role Of LC/MS in the Identification of Electrochemically Generated Products; *Regino, Merle Corazon; BrajterToth, Anna; Department of Chemistry, University of Florida, Gainesville,FL326 I I

MPG Detection ofthe Presence of Diesel Fuel in Fire Debris; *Rodden, Elizabeth; Stone, Earle; Bach, Stephan; Streeper, Robert;The University of Texas at San Antonio

MPG Flow Injection and LC/MS of Food Lipids Using Electrospray; *Sanders, Robert; Tallrnadge, Dan; Morsch, Thomas; TheProcter & Gamble Company, Cincinnati, Ohio, US

MPG RP-IP HPLC/MS/MS Detection ofPenciclovir and its Phosphorylated Derivatives; *Smyrnis, Elie, M.; Sacks, Stephen,L.; Burton, Roland; Wall, Richard, A.; Abbott, Frank; University of British Columbia, Vancouver, Canada.

MPG Capillary Supercritical Fluid Chromatography / Chemical Ionization Mass Spectrometry of Carnauba Wax; *Via,lames; Ludicky, Bob; Doster, Doug; Morton International, 1275 Lake Avenue, Woodstock, IL 60098

MPG Detection of Nitrated Products in Cosmetic-Raw Material by LC/MS with an On-Line Photolysis Reactor; *Vollmer,David; Billadeau, Mark; Lay, lack; Volmer, Dietrich; Nat'l Center for Toxicological Research, 3900 NCTR Rd, lefferson, AR72209

MPG Structural Analysis of Heat Shock Protein 27,000 by Capillary HPLC/ESI MS; *Zheng, Kefei; Qian, Mark G.; Chen,Yajuan; Lubrnan, David M.; Department of Chemistry, The University of Michigan, Ann Arbor, MI48109

SEPARATIONS/MS TECHNIQUES - INSTRUMENTATIONAbstracts are arranged alphabetically by first author

MPH Low pH Solvent Alternatives to TFA Solvents and Their Effect on HPLC/ESI-MS of Peptides; *Baldwin, Sam; Nugent,Kerry; Wheeler, Kevin; Mylchreest, lain; Michrom BioResources, Inc., Auburn, CA

MPH Micro IonSpray Mass Spectrometry Combined with Capillary LC for Protein/Peptide Analyses; *Chen, Ling; McLean,Matthew; Levery, Steve; Dupont, Dave: Yamane, Dave; Nuwaysir, Lydia; **Anacleto, loe; PE Sciex, Applied BiosystemsDivision

MPH Routine use of cone-voltage fragmentation in LC-MS; *Clayton, Eddie; Morris, Michael; Zeneca Pharmaceuticals, AlderleyPark, Macclesfield, Cheshire SKIO 4TG, UK.

MPH Correlation of On-line Microspray Emitter Geometry and Orifice Dimensions to Signal Quality; *Davis, Michael T.;Lee, Terry D.; Beckman Research Institute of the City of Hope, Duarte, CA 91010

MPH Conversion ofan HPI090 HPLC into an automated capillary HPLC with LCMS applications; *Guzzetta, Andrew;Kang, Ling-Ling; Truong, Hoai-Thu; Baldwin, Patricia; Scios Nova Inc.

MPH Hyphenation between HPLC and Liquid MALDI in an Ion traplTOF Mass Spectrometer; *He, Ling; Chen, Xin; Li,Michael X.; Lubman, David M.; Chemistry Dept. University Of Michigan. Ann Arbor. MI

MPH A Triaxial Interface for Overcoming TFA-ion Suppresion in Electrospray LC/MS of Pep tides; *Hogge, Lawrence;**Martin, Rachel; Games, David; Olson, Douglas; Ashcroft, Allison; Plant Biotechnology Institute, National ResearchCouncil, Saskatoon, Sask.

MPH Variable Flow Electrospray LC/MS/MS - Escape from the Tyranny of the Chromatographic Time Frame; *Lee, Terry;Davis, Mike; Stahl, Douglas; Swiderek, Kristine; Beckman Research Institute of the City of Hope


MPH Characterization of Bacterial Proteins Using MALDI MS Following SDS-PAGE; ·Liang, Xiaoli; Zheng, Kefei; Bai, Jian;Liu, Yan-Hui; Lubman, David M.; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109

MPH Optimization ofTLC/MALDI Coupling Protocol; ·Mehl, John, T.; Gusev, Arkady, I.; Nicola, Anthony, J.; Hercules,David, M.; Vanderbilt University. Nashville, TN

MPH Applications of Automated Capillary-HPLC/Electrospray Mass Spectrometry; ·Morris, Frank X.; Spreen, Russell C.;Zeneca Pharmaceuticals, Lead Discovery Dept., Wilmington, DE

MPH Development of Quantitative Analysis by TLC/MALDI; ·Nicola, Anthony 1.; Gusev, Arkady I.; Hercules, David M.;Department of Chemistry. Vanderbilt University, Nashville, TN 37235 USA

MPH Electrospray Mass Spectrometry of Proteins Following Comprehensive Two-Dimensional HPLC; ·Opiteck, Gregory;Jorgenson, James; Anderegg, Robert; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

MPH Quantitative Capabilities of LC/ESIIFTICRMS; ·Padley, Henry; Bashir, Sajid; Wood, Troy; State University of New Yorkat Buffalo

MPH Separation and Detection of Cellular Proteins by HPEC-MS Method; ·Rajamani, Uma; Prabhakaran, M.; Krishnamurthy,Thaiya; Biopolymer Facility, U. S. Army ERDEC. Aberdeen Proving Ground, MD

MPH Searching for Optimal Liquid Matrix Compositions for On-line LC/MALDI; ·Russon, Larry; Golding, Rafael; Whittal,Randy; Li, Liang; Department of Chemistry, University of Alberta, Edmonton

MPH Automated on-line sample handling and analysis by Micro or Capillary LC prior to MS; ·Salzmann, Jean-Pierre; vanSoest, Remco E.J.; "Vissers, Johannes; Chervet, Jean-Pierre; LC Packings (USA) Inc., 80 Carolina Street., San Francisco, CA94103

MPH 2D-PAGE, Capillary HPLC/ESIMS and MALDIIMS for Structural Analysis of Proteins; "Seta, Kazuo; ·Nakayama,Hiroshi; Shinkai, Fumiko; Isobe, Toshiaki; Kanai, Michiko; Hidenori, Ikezawa; Okuyama,Tsuneo; Biochemistry, TokyoMetropolitan University

MPH Optimized Conditions For Negative Ion LC-ESMS To Enhance Detection of Peptides and Phosphopeptides; ·Stoney,Ken; Baldwin, Sarn: "Huddleston. Michael 1.; Carr, Steven; Michrom BioResources, Inc., Auburn, CA

MPH Comparative Studies of LC/MS and MS/MS Using FT-ICR, Quadruple and Sector Mass Spectrometry; ·Xiang,Xinzhen; Dunphy, Richard; Leister, William; Burinsky, David 1.; "Winger. Brian E.; Castoro, John A. ; The R. W. JohnsonPharmaceutical Research Institute

MPH Profiling of Bacterial Proteins and Recombinant Proteins by Capillary HPLC/ MALDI MS; ·Zheng, Kefei; Liang,Xiaoli; Qian, Mark G.; Chen, Yajuan; Lubman, David M.; Department of Chemistry, The University of Michigan, Ann Arbor,MI48109

CARBOHYDRATES

Abstractsare arrangedalphabetically byfirst authorMPI A Comparison of Low and High Energy CID for the Structural Characterization of Glycopeptides; • Alexander,

Anthony ; Blackledge, James; Dodsworth, Dave; Bristol-Myers Squibb Co, Pharmaceutical Research Institute, SyracuseMPI Application of Wavelet Transforms to Electrospray Spectra: Baseline Removal; ·Barclay, V. 1.; Bonner, R. F.; Thibault,

P.; PE Sciex, TorontoMPI Development of MALDI Method for the analysis ofsulfate Oligosaccharides; ·Dai, Yuqin; Whittal, Randy; Hindsgaul,

Ole; Palcic, Monica; Li, Liang; Department of Chemistry, University of AlbertaMPI Separation and Detection oflsomers of Sucrose Derivatives by LC-MS; ·Feng, Rong; Thomson, Michael; American

Cyanamid Co., P.O. BOX 400, Princeton, NJ 08543MPI New Glycosylamine Derivatives for Sequence Analysis ofOligosaccharides by MALDI-MS and ESI-MS; .Gage,

Douglas A.; Xu, Naxing; Huang, Zhi-Heng; Dept. of Biochemistry, Michigan State University, East Lansing, MI 48824MPI Overcoming Metastable Decay and Salts in Anionic Glycoconjugates by Delayed Extraction MALDI-TOF; ·Gibson,

B.W.; John, C.M.; Hines, W.M.; Falick, A.M.; University ofCalilfomia, San FranciscoMPI MALDI-Tandem MS/MS of complex oligosaccharides examined with an orthogonal TOF analyser.; ·Harvey, David J.;

"Bateman, Robert H.; Green, Martin R.; Glycobiology Institute, Department of Biochemistry, University of Oxford.MPI A new, fast approach for sequencing oligosaccharides by exoglycosidase digestion and MALDI-TOF MS; .KUster,

Bemhard; Naven, Thomas J. P.; Harvey, David 1.; Department of Biochemistry; University of Oxford; Oxford, UKMPI Preparing oligosaccharides from glycoproteins for MALDI MS: A comparison of different procedures; ·KUster,

Bemhard; Harvey, David J.; Department of Biochemistry; University of Oxford, UKMPI Tandem mass spectrometry for characterization of oligosaccharides from keratan sulfate; Masayuki, Kubota; Takashi,

Hirano; Haruki, Niwa; ·Mamoru, Ohashi; "Keiichi. Yoshida; Akira, Tawada; The University of Electro-Communications,Chofu, Tokyo 182, Japan

MPI Fragmentation of oligosaccharides on a linear TOF mass spectrometer using delayed extraction.; ·Naven, Thomas J. P.;··Brown, Jeff.; Harvey, David J.; Glycobiology Institute, Department of Biochemistry, University of Oxford

MPI MALDIITOF Analysis of Neutral and Acidic Oligosaccharides. Is Quantitation Possible?; ·Papac, Damon; Jones, Andy;Analytical Chemistry, Genentech, Inc.

MPI Analysis ofperacetylated carbohydrates by Cr-252-PDMS utilizing matrix ion-molecule reactions; ·Pittenauer, Emst;Binder, Wolfgang; Schmid, Walther; ..Allmaier, GUnter; Institute for Analytical Chemistry, University of Vienna, A-1090Vienna

MPI Considerations of Fidelity in Glycoform Distributions Using MALDland ESI Mass Spectrometry; ·Reinhold, Bruce B.;Ye, Song; Helin, Jari; Reinhold, Vemon N.; Costello, Catherine E.; Boston University Medical School, Boston, MA 021 18

MPI MicrocapiIlary LC/Electrospray Characterization of Saccharides; ·Shahgholi, Mona; Ohorodnik, Susan; Callahan, John;Naval Research Laboratory


MPI MALDI-TOF MS ofOligosaccharides Derivatized with 4-Aminobenzoic Acid 2-(Diethylamino)ethyl Ester; *Takao,Toshifumi; Tambara, Yanet; Nakamura, Akihiro; Yoshino, Ken-ichi; Shimonishi, Yasutsugu; Institute for Protein Research,Osaka University, Suita, Osaka, Japan

MPI ESI-MS/MS ofCo(2+)-Coordinated Lewis X, Lewis a, and A-Trisaccharide; *Taw, Felicia; Brimmer, Steven; Leary, Julie;Dept. of Chemistry, University of California, Berkeley; Berkeley

MPI CE-MS analysis of carbohydrates derived from glycoproteins; Sensitivity and mobility characteristics; *Thibault, Pierre;Locke, Steven; Institute for Marine Biosciences, 141I Oxford St., Halifax, N.S., Canada

MPI Assessing the structural equivalence ofcomplex recombinant glycoproteins; *Yu, Wen; Mazsaroff, Istvan; Vath, James;Rouse, Jason; Scoble, Hubert; Genetics Institute, Andover

DRUG METABOLISM - QUALITATIVE STUDIESAbstracts are arranged alphabetically by first author

MPJ Determination of the metabolism of the Anti Helicobactor Pylori agent CP-233,S04 by HPLCIUV/APIMS; *Avery,Michael; Needham, Shane; Colizza, Kevin; Shepard, Richard; Brighty, Katherine; Fouda, Hassan; Pfizer!NC Groton, CT

MPJ Electrochemical oxidation ofpramipexole.; *Baczynskyj, Lubomyr; Althaus, John S.; VonVoigtlander, Philip F.; Pharmacia& Upjohn, Inc.

MPJ Characterization of Pt-Complex Impurities by LC-ESI-MS/MS on a Sector/OA-TOF Hybrid Instrument.; *Blackledge,James; Dodsworth, David; Alexander, Anthony; Bristol-Myers Squibb PR!

MPJ Characterization of Metabolites ofCP-1l8,9S4 in Rat Urine and Bile by LC/MS/MS; *Cui, Donghui; Prakash, Chandra;Central Research Division, Pfizer Inc., Groton, C'F06340, USA

MPJ Characterization ofCYP-4S0 Derived PGHS-II Metabolites of Arachidonic Acid Using LC ESIIMS/MS; *Garner, Carlos0.; Betas, Frank; Blair, Ian; Vanderbilt University Nashville, TN

MPJ HPLC/ESIfMS/MS Studies on the Metabolic Fate orthe Macrolide Antibiotic CP-163,SOS; *Gauthier, Jeff; Cole, Mark;Harran, Lydia; Linhares, Mike; Pfizer Inc

MP1 HPLC-APCIIMS analysis of cyproheptadine and azatadine and their microbial metabolites; *Hansen, Eugene B.;Churchwell, Mona I.; Zhang, Donglu; Cerniglia, Carl E.; Doerge, Daniel R.; National Center for Toxicological Research,Jefferson, AR

MPJ Metabolism of Mycophenolate Mofetil: Structural elucidation of both MPA and morpholine metabolites.; *Haroldsen,Peter; **Chu, Nancy; Roche Bioscience: Metabolism, Bioanalysis and Pharmacokinetics

MPJ Metabolism of spectinomycin in cattle following subcutaneous injections of 3H-spectinomycin sulfate; *Hornish, Rex;Arnold, Thomas; Gilbertson, Terry; Roof, Ryan; Wiest, John; "Davison, Kenneth; Pharmacia & Upjohn, Inc., KalamazooMI

MPJ ESIILC/MS Determination of Degraded Penicillin and Cephalosporin Antibiotics; *Kim, Jin Young; Yoo, Jong Shin;Korea Basic Science Institute

MPJ MSn to Investigate Metabolite Structures using Triple Quadrupole and Ion Trap Mass Spectrometers; *Kleintop, Brent;Lim, H.K.; Chan, Kelvin; Sisenwine, Samuel; Wyeth Ayerst Research, Princeton, NJ 08543

MP1 HPLCIRAMlESIIMS/MS Studies on the Metabolic Fate of the Anxiolytic Agent CP-93,393; *Luther, Elbridge; Cole,Mark; Soliman, Victor; Baxter, James; Fouda, Hassan; Pfizer Inc

MPJ Interpretation of mass spectra of in vitro metabolites of vitamin D and its chemical analogs; *Makin, Hugh LJ; **Jones,Glenville; Trafford, David m; Schroeder, Neil J; Calverley, Martin 1; London Hospital Medical College, London El 2AD, UK

MPJ Human liver microsomal metabolism in vitro of D-23129, a new anticonvulsant candidate; *McNeilly, Patrick; Anderson, Lawrence; Torchin, Cynthia; Kapetanovic, Izet; Kupferberg, Harvey; Strong, John; Food and Drug Administration,Rockville MD, USA

MPJ Urinary and Plasma Metabolites of LY300164 in Human, Monkey, Dog, Rat, and Mouse by LCIMS/MS; *Murphy, A.T.; Gillespie, T. A.; Eckstein, J. A.; Swanson, S. P.; Eli Lilly and Company, Indianapolis

MPJ In Vivo Formation of Ibuprofen Cholesterol Esters; *Nelson, Carolyn; Ellis, Bronwyn; Lohrer, Franzi; "Tattam, Bruce;Day, Richard; Williams, Ken; S1. Vincent's Hospital, Sydney

MPJ Rapid screening ofTaxol metabolites by LC-ESI-MS; *Poon, G.K.; Wade, J.; Bloomer, J.; Clarke, S.; Maltas, J.;SmithKline Beech am Pharmaceuticals, The Frythe, Herts

MP1 Differentiation of Regioisomeric Hydroxylated Metabolites ofCP-93,393 by lonspray LC-MSIMS.; *Prakash, Chandra;Soliman, Victor; Central Research, Pfizer Inc., Groton, CT 03440

MP1 Reactivity of Benoxaprofen Glucuronide with Human Serum Albumin; *Qiu, Yongchang; Benet, Leslie; Burlingame,Alma; Dept. Pharm. Chem., University of California, San Francisco

MPJ Use of LC/MSIMS and Column Switching for the Characterization of In Vitro Metabolites of SK&F 207499; *Schaefer,WiIliam; Dixon, Frank; Boppana, Venkatta; Ayrton, Andy; Sozio, Randall; SmithKline Beecham Pharmaceuticals, King ofPrussia

MPJ Identification ofZopolrestat Dog Metabolites by Microbore HPLC/lonspray Tandem Mass Spectrometry; *Schneider,Richard; Inskeep, Phil; Fouda, Hassan; Central Research Division, Pfizer Inc, Groton, CT 06340

MPJ Electrospray LCIMS with Radioactivity Detection of In Vitro Metabolic Reaction Mixtures; *Solsten, Thomas;URidley, Will; Mehrsheikh, Mohammed; Monsanto Company Corporate Research, St. Louis

MPJ Inhibition of Aldehyde Dehydrogenase by Disulfiram Analogs; *Veverka, Karen A.; Johnson, Kenneth L.; Tomlinson,Andy J.; Lipsky, James J.; Naylor, Stephen; Mayo Clinic, Rochester, MN 55905, USA

MPJ Mass Spectrometric Identification ofS,I2-Dihydroxy Eicosatetraenoic Acid Metabolites; *Wheelan, Pat; Murphy, RobertC.; Natl, Jewish Center for Immunology and Respiratory Medicine

MPJ APIIII (Ionspray)-MS and MSIMS Analysis of Conjugated Topiramate Metabolites in Animals and Humans; *Wu,Wu-Nan; McKown, Linda; Streeter, Anthony; Takacs, Adrienne; R. W. Johnson Pharmaceutical Research Institute


MPJ In Vitro Metabolism of Thalicarpine, An Antitumor and Antimicrobial Alkaloid, in Rat Hepatic S9; Wu, Wu-Nan;*McKown, Linda; R. W. Johnson Pharmaceutical Research Institute

MPJ API III (Ionspray)-MS and MS/MS Analysis of In Vitro Metabolites of Bepridil (VASCOR®); Wu, Wu-Nan;*McKown, Linda; R.W. Johnson Pharmaceutical Research Institute, Spring House, PA

MPJ Structural studies of mitomycin C analogue - human serum albumin adduct by MALDIlMS; *Yasuzawa, Toru; Tomer,Kenneth; National Institute of Environmental Health Sciences, Res. Tri. Pk., NC

MPJ Biotransformation ofdynorphin A (1-17) in vivo in rhesus monkey blood studied by MS; *Yu, Jim; **Butelman,Eduardo R.; Woods, James H.; Kreek, Mary Jeanne; Chait, Brian T.; The Rockefeller University, New York, NY

LASER DESORPTION - FUNDAMENTALSAbstracts are arranged alphabetically by first author

MPK Metastable Decomposition Study of Nitro-PAH in a Reflecting Time-of-Flight Mass Spectrometer.; *Bezabeh, Dawit Z.;Alien, Todd M.; Jones, A. Daniel; Kelly, Peter B.; University of California Davis, Davis, CA 95616, USA

MPK Energy Transfer Bottleneck in Matrix-Assisted Laser Desorption Revisited; Bencsura, Akos; Sadeghi, Mehrnoosh;*Vertes, Akos; George Washington University, Department of Chemistry

MPK Examining Charge State Distributions of Large Biomolecules Using MALDI-TOF; *Campo, Karen K.; Edmondson,Ricky D.; Russell, David H.; Texas A&M University, College Station

MPK A Delayed-Extraction Time-of-Flight Mass Spectrometer with a MALDI Source; *Chen, Xiangjun; Carroll, James;Beavis, Ronald; New York University

MPK Wavelength and Pulselength Dependence of IR-Matrix-Assisted Laser Desorption/lonization Processes; *Cramer,Rainer; Haglund, Jr., Richard F.; Hillenkamp, Franz; Department of Physics and Astronomy, Vanderbilt University, Nashville,TN

MPK VUV Single Photon Post Ionization for Laser Desorption Mass Speetrometry.: *de Vries, Mattanjah S.; Hunziker,Heinrich; Baumann, Reinhard; IBM Almaden Research Center, San Jose, CA95120-6099

MPK A Study of Sample Preparation Techniques for MALDI by X-ray Photoelectron Spectroscopy; Dingley, David C;*Humphrey, Paul; Smith, Alan J; Kratos Analytical, Barton Dock Road, Manchester, M41 7LD, UK.

MPK Comparison of Positive and Negative Peptide Ion Post Source Decay by MALDI-TOF MS; *Jai-nhuknan, Jaran; Cassady,Carolyn; Miami University, Oxford, Ohio

MPK Scanning laser power while acquiring MALDI spectra - Does prompt fragmentation occur at high power?; *Lavine,Gary; Allison, John; Michigan State Univeristy, East Lansing

MPK Fragmentation in MALDI-TOF Mass Spectra of some Calix[3Iindoles.; *Lidgard, Ray; McConnell, Darryl; Black, David;Kumar, Naresh; Duncan, Mark; Biomedical Mass Spectrornetry Unit, University of NSW, Sydney, Australia.

MPK Accuracy and precision of mass measurement in MALDI-MS with infrared lasers; *Menzel, Christoph; Berkenkamp,Stefan; Strupat, Kerstin; Hillenkamp, Franz; Institute for Med. Physics and Biophysics, University of Muenster, Germany

MPK Laser ablation offrozen matrices: surface processes and clusters formation.; *Nikiforov, Sergey M.; Sartakov, Boris G.;**George, Mike W.; Alimpiev, Sergey S.; Podolsky, Boris S.; General Physics Institute, Moscow, Russia

MPK Key Roles of Solvent Miscibility and Evaporation Rate in MALDI-TOF MS of Synthetic Polymer Samples;*Schoenfeld, Dean; University of Florida, Gainesville, FL 32611

MPK Mechanism orIonisation by Cation Attachment in MALDI; *Scrivener, E1aine; Maloney, Darren R; Haddleton, David M;Eason, Michael; Fong, Karen; Derrick, Peter J; University of Warwick

MPK Investigation of gas phase process of MALDI-MS using a scintilation detector; *Stahl-Zeng, Jianru; Karas, Michael;Hillenkamp, Franz; Institute for Med. Physics and Biophysics, University of Muenster, Germany

MPK MALDllnternal Energy Transfer Studies Utilizing Molecular Modeling; *Sumner, L10yd W. ; Huang, Yong; Russell,David H.; Texas A&M Univ., Laboratory for Biological Mass Spec., College Station, TX

MPK Further Resolution Improvements in Linear Matrix-Assisted Laser Desorption/lonization TOF MS; *Weinberger, Scot;uLi, Liang; Kornfeld, Richard; Whittal, Randy; Russon, Larry; Kaplun, Yevgeny; Donlon, Edward; Chemical AnalysisDivision, The Hewlett Packard Company, Palo Alto

MPK A Method for Metastable-ion Analysis in a Reflecting TOF Instrument with Precursor Ion Selection; *Westmacott,Garrett R.; Ens, Werner; Spicer, Victor L.; Standing, Kenneth G.; Dept. of Physics, Univ. of Manitoba, Winnipeg, Canada,R3T2N2

MPK Study of Mass Measurement Accuracy ora Time-Lag Focusing MALDI TOF Mass Spectrometer; *Whittal, Randy;Russon, Larry; uWeinberger, Scot; Li, Liang; Department of Chemistry, University of Alberta

MPK Understanding the Basics and Enhancing Mass Resolution for MALDI-TOFMS; *Wu, Kuang Jen; Odom, Robert;Charles Evans & Associates Redwood City, CA 94063

MPK Radial Velocity Distributions orIons Ejected by Laser Desorption; *Zhang, Wenzhu; Chait, Brian T. ; The RockefellerUniversity, 1230 York Ave., New York, NY 10021

SPRAY IONIZATION - APPLICATIONSAbstracts are arranged alphabetically by first author

MPL Application of MicrolonSpray Techniques to the Analysis of Small Volumes of Complex Samples; *Anacleto, Joseph;**Chen, Ling; PE Sciex, Concord Ontario, Canada

MPL On-line dialysis and trace-enrichment coupled with HPLC and API-Mass Spectrometry; *Bitsch, Francis; Buergin, Eva;Hersperger, Rene; Bovermann, Guenter; Sandoz Phanna Ltd, Basle, Switzerland

MPL The Rapid Identification of Metabolites by Mass Spectrometry; *Bonner, Ron; LeBlanc, Yves; uMacrae, Paul; PE SciexInstruments, Toronto, Canada


MPL Identification oran aminoglycoside degradant in drug product by LC-ESI-MS and flow injection-MS/MS; *Caesar,John P.; Buxton, Peggy A.; Waraszkiewicz, Sigmund M.; Astra USA, Inc.

MPL Identification ora boron complex impurity in SR233377 drug substance manufacture; *Chowdhury, Swapan, K.;Gonyea, George; Byard, Stephen; Sanofi Winthrop, Inc.

MPL Determination of acyclovir and guanine by microbore HPLC with confirmation by APCI.; *Cyr, Terry Donald;Kourany-Lefoll, Elly; Health Protection Branch, Drugs Directorate, Bureau of Drug Research

MPL Identification of Bioactive Peptides by LC-ESI-MS, CAD/MS and MSIMS with a Hybrid Tandem MS; *D'Agostino,Paul A.; Hancock, James R.; Provost, Lionel R.; Defence Research Establishment Suffield

MPL APCI LC/MSIMS Analysis of Bis (2ethylhexyl) Hydrogen Phosphite; *Dejarme, Lindy E.; Alexander, Carl A.; Slivon,Laurence E.; Battelle Memorial Institute

MPL The Use of LC/MS to Support Formulation Development for Physical Pharmacy Applications; *Fink, Saul; Thakur, Ajit;Slayback, John; Bristol-Myers Squibb Pharmaceutical Research Institute, New Brunswick, NJ

MPL Quantitative analysis of a new class of explosive compounds by LC-MSIMS; *Garofolo, Fabio; **Longo, Antonio;Pagliuca, Angelo; Migliozzi, Vincenzo; Tallarico, Carlo; De Rubeis, Fabio; Stama, Angelo; AMI-Aeroporto Pratica di MareDASRS-RASA 1-00040 Pratica di Mare(Rome)ITALY

MPL Analysis of Protein Digests Using a Nano HPLC Column Coupled to a Microelectrospray Source; *Hall, Steven; Maltby,David; Jarvis, S.; Hutton-McKenna, T.; Salzman, J.; Burlingame, Alma; Mass Spectrometry Facility, University ofCalifomia,San Francisco

MPL Rationalizing the Generation of Fruit Flavor: Analysis of Key Intermediates by ESI-LC-MS/MS; *Herderich, Markus;Roscher, Rene; Schneider, Claus; Schwab, WiIIi; Schreier, Peter; Lehrstuhl fllr Lebensmittelchemie, Universitat WUrzburg,WUrzburg, Germany

MPL Effects oflon Pairing Agents on Signallntensities in Electrospray and APCI Mass Spectrometry; *Iyer, Raj N.;"Giordani, Anne B.; Parke-Davis Pharm.l Res., Div. of Warner-Lambert Co., Ann Arbor, MI

MPL On-Line Nanospray Analysis of Recombinant Proteins Digest by Pneumatic Spitter-LCMS; *Le, John C.; Haniu,Mitsuru; Hui, John; Katta, Vish; Rohde, Michael; Protein Structure, Amgen Inc., Thousand Oaks, California 91320

MPL On-line Microdialysis for Sample Clean-up in Electrospray Ionization Mass Spectrometry; *Liu, Chuanliang; Wu,Qinyuan; Smith, Richard D.; Pacific Northwest National Laboratory

MPL Analysis of Steroids by Electrospray LCIMS; *Ma, Yee-Chung; **Kim, Hee-Yong; Section of Mass Spectrometry, LMBB,NlAAA, NIH

MPL Determination Of The Active Site For Peptidylglycine-alpha-Amidafing Monooxygenase by LC-ESIIMSIMS; *Marquez,Cristina D.; Treston, Anthony M.; BPRB, National Cancer Institute, Rockville, MD 20850-3300

MPL SFE and Atmospheric Pressure Chemicalloniution MS/MS Identification ofCepaenes; *Matusik, Jean; Block, Eric;White, Kevin; Calvey, Elizabeth; US Food and Drug Administration, CFSAN, Washington, DC 20204

MPL The Characterization ofDi- and Triglycerides in Oils and Fats by API LC/MS; *Mclntyre, Doug; Fischer, Steven;Hewlett-Packard Company

MPL Method for Electrospraying Solutions Containing Non-Volatile Buffers using a High Flow Sheath Liquid; *Mylchreest,lain; Sweeney, Matt; Finnigan MAT, San Jose California

MPL ESI and APCI LC/MS Application to Extractables from Drug Delivery Devices and Container Systems; *Norwood,Daniel L.; Feinberg, Thomas N.; Mullis, James 0.; Magellan Laboratories, Inc., Research Triangle Park, NC

MPL Corticosteroids determination by LC-MS ; application of a new ESI source on a high resolution MS; **Rizea Savu,Simona Marilena; *Silvestro, Luigi; Maurer, Karl Heinz; AMD Intectra GmbH, Harpstedt, Germany

MPL Matrix Related Modification of Ionization in Bioanalytical LC-API-MSIMS; *Thomas, Darren; Clarke, Steve; Hemsley,Martin; Hill, Howard; Noctor, Terry; Coming Hazleton, Otley Road, Harrogate, North Yorkshire, HG3 IPY, UK

MPL Ionization mechanisms of carotenoids during APCI and electrospray LC/MS; van Breemen, Richard B.; *Huang, ChaoRan; Tan, Yecheng; Schilling, Alexander; University of Illinois at Chicago, Chicago, Illinois

MPL Applications of ESI-TOF to LC-MS and CE-MS Characterization of Biological Molecules; *Verentchikov, Anatoli;Hsieh, Frank; Gabeler, Steve; Martin, Stephen; Vestal, Marvin; PerSeptive Biosystems, Inc., Framingham, MA

DNAlRNA STRUCTURE & ADDUCTSAbstracts arearranged alphabetically byfirst author

MPM Charactization and Identifacation ofPlatinium DNA Adducts by ESIIMSIMS; *Anderson, Lawrence; Andrews, Paul;"Cullen, Kevin; Kaup, Sahana; Strong, John; Food and Drug Adinistration, Laurel,MD, USA

MPM Analysis of Modified Oligonucleotides by CGE-ES-MS; *Barry, John P.; Vouros, Paul; The Barnett Institute, NortheasternUniversity, Boston, MA.

MPM Stable isotope labeled nucleoside and DNA standards for analysis of DNA and damaged DNA; Bi, Sheng; Quearry,Bonnie; Mekonnen, Belew; Naritsin, Dmitry; *Markey, Sanford P.; National Institute of Mental Health, Bethesda

MPM Detection and Characterization of DNA Adducts ofDBC and MDBC via FAB and ESI Mass Spectrometry; *Byun,Jaeman; Ramanathan, Ragulan; Gross, Michael; Liang, Chen; Cavalieri, Ercole; Department of Chemistry, WaShingtonUniversity, St. Louis, MO 63130

MPM Development of reversed-polarity CEIESIIMS as a new screening tool for DNA adducts; *Chambers, David; Turteltaub,Kenneth; Mauthe, Robert; Andresen, Brian; Lawrence Livermore National Laboratory

MPM Structural analysis of2'-deoxynucleotide adducts with electrospray tandem mass spectrometry.; *Esmans, Eddy;Vanhoutte, Koen; Lemiere, Filip; Van Dongen, WaIter; University ofAntwerp (RUCA), Antwerp

MPM Analysis of reaction between d(TTGGCCAA) and a Pt-complex by enzymatic degradation, ESI and MALDI; *Gonnet,Florence; Kocher, Florence; Blais, Jean Claude; Bolbach, G rard; **Chottard, Jean Claude; Tabet, Jean Claude; UniversitPierre et Marie Curie, CNRS EP 103, Paris


MPM PAH-modified DNA Adduct isomer distinction using Post Source Decay MALDI-TOF: ·Gooden, Jonathon; Byun,Jaeman; Gross, Michael; Chen, Liang; Cavalieri, Ercole; Washington University, Chemistry Department, St. Louis, MO 63130

MPM Analysis of 1,2-epoxy-3-butene Adducts ofGuanine in Calf Thymus DNA Using (LCIESI MS/MS): ·Kambouris, S. J.;Chaudhary, A. K.; Selzer, R. R.; Oe, T.; Yeola, S. N.; Elfarra, A. A.; Blair, I. A.; Vanderbilt University, Departments ofChemistry and Clinical Pharmacology .

MPM Determination of DNA Adducts from Exposure to Tetranitromethane by CE/MS: ·Keever, Jeffrey; Voyknser, Robert;Blake, James; Morgan, D.; Cunningham, Mike; Analytical & Chemical Sciences, Research Triangle Institute, RTP, NC 27709

MPM In-source-CID Electrospray MS of Modified Oligonucleotides combined with CZE; ·Linscheid, Michael; SiethotT,Christoph; ISAS Dortmund

MPM Derivatization and quantification of thymidine glycol or thymine glycol by GC/ECNI-MS: ·Naritsin, Dmitry; Bi, Sheng;Mekonnen, Belew; Quearry, Bonnie; Markey, Sanford P.; National Institute of Mental Health, Bethesda, MD

MPM A mass spectrometric investigation ofthe reaction between platinum(lI) ligand and d(CpGpTpApCpG); ·Ni, Jinsong ;McCloskey, James; "Lowe, Gordon; Vilaivan, Tirayut; Department of Medicinal Chemistry, University of Utah, USA

MPM The effect of modified base or/and sugar to the oligonucleotide dissociation in the gas phase; ·Ni, Jinsong; McCloskey,James; Davis, Darrel; Department of Medicinal Chemistry

MPM Analysis of Urinary Guanine-l,2,3,4-Diepoxybutane Adduct Using LCIESI MS/MS; ·Oe, Tomoyuki; Chaudhary, Ajai K.;Kambouris, Sara J.; Yeola, Suresh N.; Blair, lan A.; Vanderbilt University School of Medicine

MPM Electrospray Ionization FT-ICR MS Analysis of Modified Oligonucleotides; ·Pasa-Tolic, Ljiljana; Muddiman, David C.;Bruce, James E.; Smith, Richard D.; Pacific Northwest National Laboratory

MPM Quantitation and structure elucidation of in vitro and in vivo formed estrogen-DNA adducts; ·Ramanathan, Ragulan;Byun, Jaeman; Gooden, lonathon; Gross, Michael; Stack, Douglas; Cavalieri, Ercole; Washington University, Department ofChemistry, St. Louis, MO 63130

MPM High-energy collision-induced dissociation of homo-N-deoxynucleosides: ·Rozenski, lef; Hossain, Nafizal; Herdewijn,Piet; Rega Institute for Medical Research, F.F.W., K.U.Leuven

MPM Determination of Adducts ofCisplatin in DNA using CZE/ESI-MS; SiethotT,Christoph; Pongraz, Britta; ·Linscheid,Michael; ISAS Dortmund

MPM Characterization of Aldehydic Abasic Sites by Electrospray Ionization Mass Spectrometry; Torres, M. Cecilia ; Rieger,Robert A.; ·Iden, Charles R.; Department of Pharmacology, University at Stony Brook, Stony Brook, NY

MPM Quantification of Butadiene-induced DNA Adducts in vitro and in vivo using LC-MS/MS: ·Tretyakova, Natalia; Hass, J.Ronald; Swenberg, lames; University of North Carolina at Chapel Hill, Chapel Hill, NC

MPM Evaluation of detection limits for detecting DNA-adducts with API mass spectrometry.; ·Vanhoutte, Koen; Lerniere,Filip; Joos, Pieter; Van Dongen, Waiter; Esmans, Eddy; University of Antwerp (RUCA), Antwerp

MPM Sequence determination of bypass product of DNA photoadduct by ESI source CAD, MSIMS, and MALDIIPSDj·Wang, Zhen; Ramanathan, Ragulan; Gross, Michael; Taylor, John; Department of Chemistry, Washington University, St.Louis, MO, 63130

MPM Characterization of Protein-DNA Repair Complexes by Electrospray Ionization Mass Spectrometry; Zharkov, Dmitry0.; ·Rieger, Robert A.; Iden, Charles R.; Department of Pharmacology, University at Stony Brook, Stony Brook, NY

PROTEINS AND PEPTIDESAbstracts are arranged alphabetically by first author

MPN Accurate Mass Assignments of Protein Digest Fragments; ·Barbacci, Damon C.; Edmondson, Ricky D.; Russell, David H.;Texas A&M University, College Station

MPN Combining Rapid Proteolysis with Nano-electrospray Ionization for Protein Characterization: ·Blackburn, Kevin;Anderegg, Robert; GlaxoWellcome, Inc., Research Triangle Park, NC

MPN C-Terminal Ladder Sequencing for Modified Peptides by Carboxypeptidase and MALDI-MS; ·Chang, Yoon-Seok;Kim, lin-Sung; Hanyang University, Ansan, Korea

MPN Peptide Fragment-Ion Tags from MALDIIPSD for Error-tolerant Searching of Genomic Databases: ·Clauser, Karl R.;Baker, Peter; Burlingame, Alma L.; Department of Pharmaceutical Chemistry, Univ. of California, San Francisco

MPN Automated characterization of proteins by liquid chromatography - tandem mass spectrometry; ·Ducret, Axel; Eng,Jimmy; Yates, Ill, John; Aebersold, Ruedi; Dept of Molecular Biotechnology, University of Washington, Seattle WA 98195

MPN Improvements in Mass Measurement Accuracy ofMALDI-TOF; ·Edmondson, Ricky D.; Russell, David H.; Texas A&MUniversity, College Station

MPN An Interactive Environment on the World Wide Web for Protein Mass Spectrometry; ·Fenyll, David; Zhang, Wenzhu;Beavis, Ron C.; Chait, Brian T.; The Rockefeller University, New York, NY 10021

MPN PepFrag - a Software Tool for Protein Identification Using MS/MS Information; ·Fenyll, David; Qin, Jun; Chait, BrianT.; The Rockefeller University

MPN Automated On-Line LCIMS Methods for Protein Sample Cleanup and Characterization: ·Hail, Mark E.; Nedved,Michael L.; Warrack, Bethanne M.; Thompson, William L.; Lee, Mike S.; Bristol-Myers Squibb Pharmaceutical ResearchInstitute, Princeton, NJ

MPN Peptide Sequencing by MALDI-TOF using Direct and Database Strategies: ·Hines, Wade; Patterson, Dale; Takach, Ed;Vestal, Marvin; Martin, Stephen; PerSeptive Biosystems,Inc., Framingham MA

MPN Protein Ladder Sequencing Peptides Containing Lysine After Enzymatic Digestion Using MALDIITOF MS; Holland,Ricky D.; ··Persons, Cecil; ·Heinze, Thomas M.; Lay, Jr., Jackson 0.; National Center for Toxicological Reseach, JetTerson,AR, 72079


MPN Novel picomole scale derivatization of peptides with a tris(trimethoxyphenyl)phosphonium moiety; *Huang, Zhi-Heng; .Wu, Jiang; Yang, Ying; Watson, J. Throck; Gage, Douglas A.; Department of Biochemistry, Michigan State University, EastLansing

MPN Ragged end peptides as probes for protein identification by mass spectrometry and database searches; *Jensen, DieNl,rregaard; Vorm, Die; Mann, Matthias; European Molecular Biology Laboratory (EMBL), D-69012 Heidelberg, Germany

MPN Characterization of Errors in the Molecular Weight Measurement of Proteins by ESI; *Johnson, Kenneth L.; Tomlinson,Andy J.; Naylor, Stephen; Mayo Clinic, Rochester, MN 55905, USA

MPN Strategies for Protein Characterization: Membrane Preconcentration and Low Flow ESI; *Johnson, Kenneth L.;Tomlinson, Andy 1.; Clarke, Nigel J.; Naylor, Stephen; Mayo Clinic, Rochester, MN 55905, USA

MPN Improved Peptide Analysis Using "ZoomScan" on an LCIMSIMS Ion Trap Mass Sectrometer; *Land, Adrian P.;Sanders, Mark; Schwartz, Jae; Finnigan MAT, 355 River Oaks Parkway, San Jose, CA 95134

MPN Direct Analysis of Crude Protein Mixtures by MALDI MS With the Aid of Polymeric Substrates; *Liang, Xiaoli; Bai,Jian; Cain, Teresa C.; Liu, Yan-Hui; Lubman, David M.; Department of Chemistry, The University of Michigan, Ann Arbor,MI48109

MPN MS Applied to Structural Investigations of Hydrogen Cyanide Polymers; *Minard, Robert; Matthews, Clifford; Hatcher,Patrick; Gourley, Chris; Penn State University

MPN On-line purification of proteins using a polymeric reversed phase gel with micro-ESIMS; *Nakanishi, Toyofumi;Shimizu, Akira; Caprioli, Richard; University of Texas Medical School, Houston, Texas 77030

MPN Structural Identification ofthe N-terminal Neutral Losses from Protonated Peptides; *Nold, Michael ; Wesdemiotis,Chrys; Chemistry Department, The University of Akron, Akron Ohio 44325-3601

MPN Identification of Proteins by MicrolonSpray Mass Spectrometry of Enzymatic Digests; *Nuwaysir, Lydia; McLean,Matthew; Bonner, Ron; Yamane, Dave; Chen, Ling; PE Sciex, Applied Biosystems Division

MPN Identification of Mouse Liver Proteins on 2-D Gels by MALDI-MS of in situ Enzymatic Digests; *O'Connell, Kathy;Powell-Braxton, Lyn; Warburton, Cara; Stults, John; Genentech, Inc., South San Francisco, CA 94080

MPN The use of n-butyl esters to improve the ESI-MS and ESI-MS/MS analysis of peptides and amino acids;*Papayannopoulos, loannis A.; Biogen Inc., Cambridge, MA

MPN High Confidence Identification of Gel-Separated Proteins; *Qin, Jun; Fenyo, David; Zhao, Yingming; Chait, Brian; TheRockefeller University, 1230 York Ave., New York, NY 10021 .

MPN Copper Stain Provides an Effective Interface between Gel Electrophoresis and Mass Spectrometry; Qin, Jun; Wang, Vi;*Chait, Brian; The Rockefeller University, 1230 York Ave., New York, NY 10021

MPN Mass Spectrometry as a Tool in Systematic Peptide Sequencing; *Raida, Manfred; Heine, Gabi; Schulz-Knappe, Peter;Forssmann, Wolf-Georg; Niedersaechsisches Institut fuer Peptid-Forschung, Hannover, Germany

MPN Mass Spectrometric Analysis of Peptide Mixtures, Comparison of LC-MS and MALDI-MS; *Raida, Manfred; Schrader,Michael; Neitz, Susanne; Forssmann, Wolf-Georg; Niedersaechsisches Institut fuer Peptid-Forschung, Hannover, Germany

MPN The Effect of Delayed Extraction on the MALDI-PSD and MALDI-PSD-CID Mass Spectra of Peptides; *Roberts,Gerald D.; Carr, Steven A. ; Hemling, Mark E.; Critchley, Glenn (2); **Brown, Jeff(2); Hoyes, John (2); SmithKlineBeecham Pharmaceuticals, King of Prussis, PA 19406

MPN Application ofMALDI-FTMS to Protein OLadderO Sequencing; *Scott, JiII R.; SchYrch, Stefan; Moore, Sean; Wilkins,Charles L.; University of California, Riverside

MPN Large Scale Identification of Yeast Proteins Exc:lusively by Mass Spectrometric Methods; *Shevchenko, Andrej; Wilm,Matthias; Jensen, Die; Vorm, Die; Shevchenko, Anna; Sagliocco, Francois; Boucherie, Helain; Mann, Matthias; EuropeanMolecular Biology Laboratory (EMBL)

MPN Sample Preparation Techniques for Femtomole Sequencing of Proteins from Polyacrylamide Gels; *Shevchenko,Andrej; Jensen, Die; Wilm, Matthias; Mann, Matthias; European Molecular Biology Laboratory (EMBL)

MPN Directing Fragmentation for Primary Structure Elucidation of Pep tides by Postsource Decay MALDI; *Spengler,Bernhard; Luetzenkirchen, Frank; Metzger, Sabine; Kaufmann, Raimund; Jeffery, William; Pappin, Darryl J. C.; Inst. of LaserMedicine, Univ. of Duesseldorf, Germany

MPN MALDI Mass Measurement Accuracy of Proteins Directly from Polyacrylamide Gels and Membranes; *Stevenson,Tracy I.; **Ogorzalek Loo, Rachel R.; Mitchell, Charles; Loo, Joseph A.; Andrews, Philip C.; Parke-Davis PharmaceuticalResearch, Ann Arbor, MI

MPN Fragmentation properties of protonated peptides with both acidic and basic amino acid residues; *Summerfield, ScottG.; **Kingston, Robert; Gaskell, Simon J.; Michael Barber Centre for Mass Spectrometry, UMIST, Manchester, U.K.

MPN The Analysis of Myocardial Proteins by Infrared and Ultraviolet Laser Desorption Mass Spectrometry.; *Sutton, C. W.;U., S.; Evans, S.; Corbett, J. M.; Wheeler, C. H.; **Dunn, M. J.; Thermo BioAnalysis Ltd., Hemel Hempstead, UK

MPN Positive Identification of Proteins by Peptide Maps with High Mass Accuracy and Sequence Coverage; *Vorm, Die;Jensen, Die N.; Mann, Matthias; Dept. of Chemistry, Odense University, Denmark

MPN Protein Characterization at the Picomole level with Coupled Capillary LCIMS Systems; *Wang, Hongqi; Jindal, Satish;Carson, Bill; Martin, Stephen; Regnier, Fred; PerSeptive Biosystems, Framingham, MA

MPN Carboxyl-terminal ladder sequencing of pep tides for protein identification; *Wang, Rong; Sechi, Salvatore; Chait, Brian;The Rockefeller University

MPN A Novel Strategy for Assignment of Disullide Bond Pairing in Proteins; *Watson, J.T.; Wu, Jiang; Dept. ofChemistry,Michigan State University, East Lansing, MI 48824

MPN DeconvoIution of Natural Isotopic Abundance Patterns by Least Squares and Maximum Entropy Methods; *Zhang,Zhongqi; Guan, Shenheng ; Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL


MPN Characterization of an Unstable Intermediate Formed During Cyanogenbromide Cleavage of a-endorphin; Zhang,Xinyi; Dillen, Lieve; ·Claeys, Magda; Van Dongen, Waiter; Vanhoutte, Koen; Esmans, Eddy; University of Antwerp (VIAand RUCA)

TUESDAY POSTERS

ION-MOLECULE REACTIONSAbstracts are arrangedalphabeticaUy byfirst author

TPA Ion-Molecule Reaction Kinetics at Your Fingertips.; •Anicich, Vincent; Jet Propulsion LaboratoryTPA A Collision Cell with Electrostatic Ion Guide for Collision Cross Section Study of Protein Ions; ·Bondarenko, Pavel;

Macfarlane, Ronald; Department of Chemistry,Texas A&M University, College Station, TX 77843TPA Dimethyl ether Cl mass spectrometry of isomeric methylated nucleic acid bases and nucleosides; ·Burrows, E. P.;

USACHPPM Research Detachment,Fort Detrick, Frederick, MDTPA Gas-Phase Basicity Determinations of High Basicity Amino Acids and Small Peptides; ·Carr, Scott R.; Cassady, Carolyn

J.; Miami University, Oxford, OhioTPA The Unexpected Reactivity ofPhenylium Ions; ·Chou, P. K.; Nousiainen,1.; Perez, J.; Kenttamaa, H. I.; Department of

Chemistry, Purdue UniversityTPA Reactions of Ar+ ions with C02 and S02 at high temperatures.; ·Dotan,ltzhak; Viggiano, AI.A; Phillips Laboratory,

GPID, Hanscom AFB, MA 01731-3010, U.S.ATPA A PMO theory of gas-phase proton-transfer rates; ·Dougherty, Ralph; Dept of Chemistry, Florida State University,

Tallahassee FL 32306-3006TPA Intermediates in Sulphur-rich Flames - On the Identity ofthe C2H3S+ Chemi-ion; ·Egsgaard, Helge; Carlsen, Lars;

Sorrilha, Ana Elisa P. M.; Eberlin, Marcos N.; Ris; National Laboratory, DK-4000 Roskilde, DenmarkTPA Toluene Cl vs Methane/Ammonia Cl for the Anaylsis of Methyl Esters; ·Evans, Jason; Munson, Burnaby; Nicol, Gordon;

University of DelawareTPA Gas-Phase Basicities of Small Peptides of Proline and Glycine: The Enhanced Basicity of Pro Pro; ·Ewing, Nigel; Zhang,

Xin; Cassady, Carolyn; Miami University, OxfordTPA The CH30H+¥ I H2O AND C2HSOH+¥ I H20 systems: a M.O. approach; Fossey, Jacques; Dahhani, Fadil; •Audier,

Henri; DCMR, CNRS URA 1307, Ecole Polytechnique,F-91128 PALAISEAUTPA 2,3-Dihydrofuran and 2,S-Dihydrofuran Radical Cations; ·Gao, Lan; Nousiainen, Jaakko; Kenttamaa, Hilkka; Department

of Chemistry, Purdue University, West LafayetteTPA Gas phase reactions ofsilicon and boron hydride cations in the FA-SIFT; ·Gareyev, Roustam; Damrauer, Robert; DePuy,

Charles H.; Department of Chemistry and Biochemistry, University of Colorado at BoulderTPA Mechanisms of water losses from els and trans indanediol adduct ions in dimethylether Cl; Gervat, Vincent; Fournier,

Francoise; Perlat, Marie-Claude; ·Tabet, Jean-Claude;Universite Pierre et Marie Curie (PARIS)TPA The Role of Proton-Bridged Intermediates in Gas-Phase H-D Exchange Reactions; ·Green, M. Kirk; Lebrilla, Carlito B.;

University of California, DavisTPA Structure Determination in a Series of Substituted Silacyclobutane Ions Using Triple Quadrupole MS; ·Hankin, Joseph

A.; "Damrauer, Robert; University of Colorado at Boulder; Boulder, CO 80309TPA Tandem Mass Spectrometry of Gas Phase Protonated Organophosphorus Compounds; ·Hesso, Antti; Tornaeus, Jarkko;

"Bjoerk, Heikki; Finnish Institute of OccupationalHealth, Helsinki, FinlandTPA Distonic Ions otthe "ate" Class; ·Hill, Brian T.; Chyall, Leonard J.; Poutsma, John C.; Hu, Jun; Squires, Robert R.; Purdue

University, Department of Chemistry, West Lafayette, IN 47907TPA Synthesis and Characterization of Distonic Biradicallons; ·Hu, Jun; Squires, Robert R.; Purdue University, Department of

Chemistry, West Lafayette, IN 47907TPA Unexpected addition reactions observed in isobutane Cl in new generation ITD.; • Jalonen, Jorma; Joensuu, Paivi;

Department of Chemistry, Univ. ofOulu, POB 333, FIN-90S7! Oulu, FinlandTPA Reactivity ofthe epimeric 3, 4-chromanediols towards the NH31NH4+ system; Kang, Yoon-Joo; Meyer, Michele; Dana,

Gilbert; ·Fournier, Francoise; Tabet, Jean-Claude; UniversitePierre et Marie Curie (Paris)TPA The Bronsted Acidity of Simple Aldehyde and Ketone Radical Cations; Kenttamaa, Hilkka I.; ·Byrd, H.C. Michelle;

Department of Chemistry, Purdue University, West LafayetteTPA HydrogenlDeuterium Exchange in the Reactions of Methyl Cation with Methane; ·Lee, Hack Sung; Bierbaum, Veronica

M.; DePuy, Charles H.; Department of Chemistry, University of Colorado at BoulderTPA Reactions of chloroorganics with oxygen in the collision cell of a triple quadrupole.; ·Lepine, Francois; Boismenu,

Daniel; Mamer , Orval; Institut Armand-Frappier,Laval, Quebec, CanadaTPA Fluorine Substitution Enhances the Reactivity of Charged Phenyl Radicals Tow.ard Hydrogen Atom Donors; ·Li,

Ruomei; Smith, Rebecca L.; Kenttamaa, Hilkka I.; Purdue University, West Lafayette, IN 47907-1393TPA Gas Phase Reactions of Metal Ions oflnterstellar Interest; ·Linder, Christopher; Babcock, Lucia; University of Georgia,

Athens, Georgia, 30602TPA A Gas-Phase Structurally Diagnostic Ion-Molecule Reaction for 1,3-0,0- and 1,3-0,S-Heterocycles.; Moraes, Luis

Alberta B.; Gozzo, Fabio C.; Eberlin, M. N.; "Vainiotalo, Pirjo; State University of Campinas, Institute of Chemistry,Campinas, Brasil.

TPA Neutral Products from Rearrangements of2-Hydroxyethyl Cations Produced by Tritium Decay; ·Morton, ThomasHellman; Bennett, Jacqueline S.; University of California, Riverside


TPA Cation Attachment to Multiply-Charged Anions of Bovine Insulin A-chain; McLuckey, Scott A.; *Goeringer, Douglas K;Herron, William J.; Stephenson, James L.; Oak Ridge National Laboratory

TPA Gas-Phase Reactivity of Simple Ionized Carbenes; *Nelson, Eric D.; Thoen, Kami K.; Kenttamaa, Hilkka I.; PurdueUniversity, West Lafayette, IN

TPA The Structure ofProtonated Aniline in the Gas Phase; *Nold, Michael; Wesdemiotis, Chrys; Chemistry Department, TheUniversity of Akron, Akron Ohio 44325-3601

TPA El and Cl Mass Spectra of Some Oligomeric Polyethylene Glycols and Ethers; *Onigbinde, Adebayo; Nicol, Gordon;Munson, Bumaby; University Of Delaware, Newark DE 19716

TPA Gas-Phase Negative Ion Chemistry of Lewis Acid-Base Complexes; *Ren, Jianhua; Workman, Derek B.; Squires, RobertR.; Purdue University, Department of Chemistry, West Lafayette, IN 47907

TPA H-atom and N-atom reactions with Molecular Ions.; Scott, Graham; Fairley, David; Freeman, Colin; *McEwan, Murray;University of Canterbury, Christchurch, New Zealand.

TPA High Pressure Electron Capture Responses and Spectra of Substituted Nitrobenzenes; *Sears, L.J.; Knighton, W.B.;Grimsrud, E.P.; Montana State University Bozeman, MT

TPA The Detection and Study of Electronically Excited Species in the Cl Source; *Stemmler, Elizabeth; Wert, Bryan;Bowdoin College, Brunswick

TPA Probing Substituent Effects on the Reactivity of Charged Phenyl Radicals; *Thoen, Kami K.; Stumpf, Chris L.;Kenttarnaa, Hilkka I.; Purdue University, West Lafayette, IN

TPA Distinction between propenyl and allyl cations: HID exchange with D20.; van der Rest, Guillaume; *Mourgues, Philippe;Audier, Henri Edouard; Ecole Polytechnique DCMR - URA CNRS 1307

TPA Oxygen Exchange in the Formaldehyd-Water Proton Bound Dimer; van der Rest, Guillaume; Fossey, Jacques; Mourgues,Philippe; *Audier, Henri-Edouard; Laboratoire des M canismes R actionnels - URA CNRS 1307 Palaiseau

TPA Reactions of Simple Ions and Water/Acetonitrile Ion Clusters with Acetonitrile Molecules; *Vinogradov, P. S.;Borisenko, D. M.; Veretennikov, I. N.; Institute of Energy Problems of Chemical Physics, Russian Academy ofSci.

TPA Generation of neutral silaethenes by neutralization-reionization mass spectrometry; *Zagorevskii, Dmitri; Dakubu, M.;Holmes, John L.; Chemistry Department, University of Ottawa, Ottawa, Ontario, Canada KIN 6N5

TPA Determination of Gas Phase Basicities of Multiply Protonated Peptide Ions by FT-MS; *Zhang, Xin; Cassady, Carolyn;Miami Univeristy, Oxford, Ohio

ION ACTIVATION AND DISSOCIATIONAbstracts are arranged alphabetically byfirst author

TPB Background Reduction In Photodissociation Spectra by Improved Sample Preparation; *Barbacci, Damon C.;Edmondson, Ricky D.; Russell, David H.; Texas A&M University, College Station

TPB Carbohydrate Analysis Using ElectrospraylPhotodissociation in the Quadrupole Ion Trap; *Boue, Stephen M.;Stephenson , James L. (2); Yost, RA (I); University of Florida

TPB Infrared Multiphoton Photodissociation in a Quadrupole Ion Trap Mass Spectrometer; *Colorado, Armando; Brodbelt,Jennifer; University of Texas, Austin, TX

TPB Comparison between SID and Thermal Decomposition Kinetics of Non-Specific Dimers; *Dongre, Ashok; Somogyi,Arpad; Nair , Hari; Meot-Ner, Michael; Wysocki, Vicki; Virginia Commonwealth University

TPB Systematic Studies to Test the Validity of the Mobile Proton Model for Fragmentation of Peptides; *Dongre, Ashok;Somogyi, Arpad; Jones, Jennifer; Wysocki, Vicki; Virginia Commonwealth University

TPB Steps on the Road to Interpretation of Photo-Induced Dissociation Spectra; *Erickson, Tina; Beussman, Douglas;Constantopoulos, Terri; Enke, Chris; University ofNew Mexico, Albuquerque

TPB Enrichment and Characterization ofthe Noble Gas Fullerene Ar@C60; *Hettich, Robert; DiCamillo, Barbara; Compton,Robert; Guiochon, Georges; Oak Ridge National Laboratory

TPB Probing reactions occurring during surface induced dissociation(SID) tandem mass spectrometry(ms/ms); *Manzella,Lynn; **Hayward, Mark; Bemasek, Steven; Department of Chemistry- Princeton University-Princeton, NJ

TPB Photodissociation of Dye Molecular Ions in an RF Ion Trap; *Michisato, Toyoda; Masahiro, Kimura; Takekiyo, Matsuo;Dept. of Physics, Fac. of Science, Osaka University

TPB Soft-landing of polyatomic ions at fluorinated self-assembled monolayers; *Miller, Scott; Luo, Hai; Cooks, R. G.;**Pachuta, Steven; Purdue University

TPB Microchannel plate surface-induced reactions at the entrance of a RF-only quadrupole.; *Mouget, Yves; Bertrand,Michel J.; University of Montreal, Montreal.

TPB Effect ofN-alkylation of Amide Bond on Its Cleavage by SID; Demonstration of the Proline Effect; *Nair, Hari;Somogyi, Arpad; Wysocki, Vicki; Virginia Commonwealth University

TPB "The mobile proton model of peptide fragmentation: comparison ofSID and CID data"; *Nair, Hari; Wysocki, Vicki;Summerfield, Scott; Gaskell, Simon; Virginia Commonwealth University, Richmond

TPB Blackbody Infrared Dissociation: Binding Energies of Non-Covalent Biomolecule Complexes in Vacuo; *Schnier, Paul;Price, William; Williams, Evan; University of Califomia, Berkeley

TPB Addition ofH, F, and CH3 to Small Organic Projectiles in Low Energy Ion-Surface Reactions; *Somogyi, Arpad;Shillady, Donald; Wysocki, Vicki; Virginia Commonwealth University

TPB Activation Energy of Fragmentation ofProtonated Peptides Determined by a New Approach; *Vekey, Karoly;**Somogyi, Arpad; Wysocki, Vicki; Nair, Hari; Central Research Institute for Chemistry of the Hungarian Acad. of Sciences

TPB Analysis of Fragment Ion Kinetic Energy Distributions During Surface-Induced Dissociation; *Wainhaus, Samuel B.;Urn, Hanjo; Schultz, David; Hanley, Luke; University of Illinois at Chicago


TPB Thermochemical Measurements with Surface-Induced Dissociation; *Wainhaus, Samuel 8.; Schultz, David; Lim, Hanjo;Hanley, Luke; University of Illinois at Chicago

TRAPPED IONSAbstracts are arranged alphabetically by first author

TPC Characterization ofMALDIIFfICR Performance With an Inhomogeneous Superconducting Magnet; *Anderson, J.S.;Laude, D.A.; The University of Texas at Austin

TPC Techniques for Uncoupling Coalescing Isotopic Distributions in MALDIIFfICR; *Anderson, J.S.; Laude, D.A.; TheUniversity of Texas at Austin

TPC FTICR Ion Remeasurement Techniques for Small Molecules; *Blakney, G.T.; Karpinski, M.L.; Laude, D.A; TheUniversity of Texas at Austin

TPC Magnetic Field Focusing Electrospray FTICR on a High Field Magnet; Drader, 1.1.; Hendrickson, C.L.; Robinson, J.M.;*Laude, D.A; Dept. of Chemistry and Biochemistry, The University ofTexas at Austin

TPC High Resolution, High Mass Accuracy, and Performance with an Internal MALDlICR; *Easterling, Michael;Pitsenberger, Cynthia; Kulkami, Shubhada; Taylor, Kristi; Amster, I. Jonathan; University of Georgia

TPC MALDI FT-ICR MS Analysis of Luteinizing Hormone Releasing Hormone at Biological Concentrations; *Emmett,Mark R.; Solouki, Touradj; Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

TPC Characterization ofa Multi Electrode Ion Trap; *Engelmohr, Peter; Wanczek, Karl Peter; Inst. ofInorg. and Phys.Chemistry, University of Bremen, D-28344 Bremen

TPC Modeling oflon Injection and Trapping for a Versatile External Source FTMS System; *Futrell, Jean; Nikolaev, Eugene;Rakov, Sergey; uBecker, Bruce; Winger, Brian; Campana, Joe; University of Delaware, Newark, DE

TPC Hadamard Transform FTICRMS of Multiply-charged Protein Ions; *Gao, Xuling; Wood, Troy; State University of NewYork at Buffalo

TPC Theoretical description of a Wire Ion Guide (WIG) cell; Gillig, Kent; *Bluhm, Brian; Russell, David; Texas A&MUniversity College Station

TPC Dependence ofFT-ICR Time-Domain Signal Decay Envelope on Ion-Neutral Collision Mechanism; *Guan, Shenheng;Li, Guo-Zhong; Marshall, Alan. G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

TPC Internal Energy Deposition by Quadrupolar Excitation in the Presence of CoIIisiona I Cooling; *Guan, Shenheng; Xin,Tianpei; Reinhold, Bruce B.; Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

TPC On-Line, Capillary HPLC Interface for a Magnetic Field Focusing ESIIFTICR; *Harper, C. J.; Bolanos, B. J.; Arkin, C.R.; Torres, T. A; Schmidt, E. G.; Laude, D. A; The University ofTexas at Austin

TPC MALDI FT-ICR Mass Spectrometry in a 20 Tesla Resistive Magnet; *Hendrickson, Christopher L.; Guan, Shenheng;Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

TPC Scaling Factors for Excitation Potentials in Tetragonal and Cylindrical Penning Traps; *Jackson, George S.; Guan,Shenheng; Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

TPC Selective Broadband Quadrupolar Axialization in FTICR; *Karpinski, M.L.; Blakney, G.T.; Bolanos, BJ.; Laude, D.A.;The University of Texas at Austin

TPC A Small Permanent Magnet FT-ICR Spectrometer; *Kofel, Peter; Institute of Organic Chemistry, University of Bern, CH3012 Bern

TPC Characterization of Open ICR Cells with Trajectory Calculation; *Kuhnen, Florian; Wanczerk, Karl Peter; Inst. of Inorg.and Phys. Chemistry, University of Bremen, D-28334 Bremen

TPC Nanoelectrospray Ionization FTICR Spectrometry of Metalloproteins; *Kulkami, Shubadha; Taylor, Kristi; Amster,Jonathan; Department of Chemistry, University of Georgia, Athens, GA 30602-2556

TPC Distribution and Density of Trapped Ions; *Li, Guo-Zhong; Guan, Shenheng; Marshall, Alan G.; National High MagneticField Laboratory, Florida State Univ., Tallahassee

TPC Assessment of ion-trapping efficiency in FTMS-SORI by computer simulation of ion trajectories; **Naito, Yasuhide;*Inoue, Masao; Univ. ofElectro-Communications, Tokyo, Japan

TPC Determination of excitation frequency for fixed-frequency pulse excitation waveform in FT-ICRlMS; *Naito, Yasuhide;Inoue, Masao; Univ. ofElectro-Communications, Tokyo, Japan

TPC Capabilities of Broadband Quadrupolar Axialization Over a Wide Mass Range; *Pitsenberger, Cynthia C.; Easterling,Michael L.; Amster, I. Jonathan; The University of Georgia

TPC Compensation and RF-Only Mode for Improved Detection of High Mass in a Superconducting Solenoid FTMS;*Rempel, D. L.; Holliman, C. L.; Jacoby, C. B.; Ramanathan, R.; Gross, M. L.; Department of Chemistry, WashingtonUniversity, St. Louis, MO 63130-4899

TPC Approaches to Ion Mobility Measurements in an FTICR Spectrometer; *Schmidt, E.G.; Laude, D.A.; The University ofTexas at Austin

TPC Electronspray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry at 9.4T; *Senko, Michael W.;Hendrickson, Christopher L.; White, Forest M.; Quinn, John P.; Marto, Jarrod A.;'Pasa-Tolic, Ljiljana; Guan, Shenheng;Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

TPC Ion Storage Mass Spectrometry for Sequencing MHC Class-Il Peptides; *Settlage, R.E.; Marto, lA.; Yates, N.A.;Shabanowitz, J.; Hunt, D.F.; University of Virginia

TPC Semiconductor Gas Purity and Process Characterization by FT-ICR; *Smith, Derek; Brooks, Larry; Hoffman, John;**Hogan, Jerry; Chorush, Russell; University of Texas at Dallas Richardson

TPC Charge State of Substituted Sulfurhexafluorides; SpieB, Iris; Kuhnen, Florian; *Wanczek, Karl Peter; Inst. ofInorg. andPhys. Chemistry, University of Bremen, D-28334 Bremen


TPC Distinction ofCoulombic and Conformational Effects on Dissociation ofElectrosprayed Proteins; *Stevenson, E.;Bolanos, B. J.; Campbell, V. L.; Arkin, C. R.; Laude, D. A.; The University ofTexas at Austin

TPC Optimization ofan lea-Ion Pulse Sequence for Negative ESI Ions in a Five-Electrode Trapped-Ion Cell; *Torres, T.A.;Stevenson, E.; Harper, C.J.; Laude, D.A.; The University ofTexas at Austin

TPC A Systematic Approach to Improve Mass Accuracy in FrICR Mass Spectrometry at Zero Trapping Potential; *Watson,Clifford H.; Goodner, Kevin L.; Eyler, John R.; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200


TPD Laser Desorption Ionization TOF Mass Spectrometric Analysis of Chromium Containing Particulates; *Allen, Todd M.;Bezabeh, Dawit Z.; Jones, A. Daniel; Kennedy, Ian M.; Kelly, Peter B.; University of California, Davis

TPD Comparative Evalutaion ofthe TCLP Zero-Headspace and Bottle Extractions Procedures; *Beihoffer, Jon; Seidel,Jimmy; Terry, Corey; U.S. EPA National Enforcement Investigations Center, Denver, CO

TPD Assessment ofVOC Emissions from Chlorinated Drinking Water in Showers; *Benoit, Frank; "Mori, Brian; AlIeyne,Carl; Health Canada, Environmental Health Directorate, Ottawa ON Canada

TPD Electron Energy-Dependent Regioselective Loss of Chloride Anions from Polychlorodibenzo-p-dioxins; *Berkout,Vadym; Laramee, James; Deinzer, Max; Dept. of Agricultural Chemistry, Oregon State University, Corvallis, OR

TPD Evolving Criteria for Mass Spectral Confirmation at Trace Levels; *Cairns, Thomas; Psychemedics Corporation, CulverCity, CA 90230

TPD MALDI-TOF of Low Molecular Weight Organic Acids; *Campbell, James A.; Goheen, Steve c.; Wahl, Karen L.; Hess,Wayne P.; Pacific Northwest National Laboratory

TPD A Study of the Fuel/Air Ratio on Polymer Combustion Emissions by GC/MS; *Carlson, Joel; Dunayevskiy, Yuriy;Vouros, Paul; Atal, Ajay; Panagiotou, Thomai; Levendis, Yiannis; Dept. of Chem., Northeastern Univ., 360 Huntington Ave,Boston, MA, 02115

TPD Statistical Methods for Determining Detection and Quantitation Limits; *Coleman, David; Bethem, Robert; AlcoaLaboratories, Alcoa Center, PA

TPD A transportable isotopic dilution GC-MS system for atmospheric monitoring while driving in traffic; *Davoli, Enrico;Cappellini, Luigi; Moggi, Marco; Ferrari, Stefano; Fanelli, Roberto; Istituto di Ricerche Farrnacologiche Mario Negri

TPD Direct Capillary Column Desorption for GCIMS Analysis at High Helium Flow Rate; *Dejarrne, Lindy E.; Ray, Prasenjit;Slivon, Laurence E.; Battelle Memorial Institute

TPD A Field Portable Aerosol-Time-of-Flight Mass Spectrometer; *Dienes, Tas; Fergenson, David; Gard, Eric; Morrical, Brad;Prather, Kimberly A.; University of California, Riverside

TPD Ultra Trace Analysis of Atmospheric Halocarbons using High Resolution Mass Spectrometry; *Engen, M.A.; Grimsrud,E.P.; Montana State University Bozeman, MT

TPD Rapid Analysis ofTO-14 Airborne Contaminants By Fast GCITOFMS; *Gardner, Ben; Holland, John; "Berkley,Richard; Michigan State University

TPD Modeling Pyrolysis of PVC using FT-ICR; *Glaser, Brian S.; Haworth, James E.; Philips, Eugene; Hanson, Curtiss D.;University of Northern Iowa, Department of Chemistry, Cedar Falls, lA

TPD Applications of Mass Peak Profiling from Selected Ion Recording Data using Probe Introduction; *Grange, Andrew H.;"Brumley, WilIiam C.; Lockheed Environmental Systems and Technologies Company

TPD Static SIMS Investigation of Phosphazene Polymers used for Contaminant Adsorption; *Groenewold, Gary; Cowan,Rob; Ingram, Jani; Appelhans, Anthony; Delmore, Jim; Idaho National Engineering Laboratory, Idaho Falls, ID

TPD Monitoring Volatile Organic Compounds in Gaseous Process Streams; *Hart, Kevin J.; Dindal, Amy B.; Smith, Rob R.;Oak Ridge National Laboratory

TPD Mechanisms of High Energy Combustion Reactions of Polyisoprene Pyrolysis; *Haworth, James E.; Glaser, Brian S.;Phillips, Eugene; Hanson, Curtiss D.; University of Northern Iowa, Cedar Falls, la

TPD GCIMS Determination of Metsulfuron methyl and Chlorsulfuron in Natural Waters - Matrix Effects; *Headley, John;**MacDonald, Linda; Peru, Kerry; National Hydrology Research Institute, Saskatoon

TPD Analysis of haloacetic acids in drinking water by supercritical Ouid extraction/methylation; *Her, G.R.; Sheen, J.F.;Department of Chemistry, National Taiwan University, Taipei, Taiwan, R.O.C.

TPD Identification of Photodegradation Products ofDDT and Its Metabolites in Water; *Hong, Jongki; Yoo, Jong-Shin; So,Hun-Young; **Jung, Seong- Young; Kim, Kang-Jin; Korea Basic Science Institute, 224-1, Eoun-dong, Yusong-ku, Tajeon,Korea

TPD GC-MS Confirmation Analysis of a Low Volatility Organophosphorus Toxic Agent in Air Samples; *Jakubowski,Edward; Deel, GaH; SciTech Services Inc., Abingdon, MD 21009

TPD Tandem and High Resolution Mass Spectrometry with FAH Ionization Analysis of Quat Pesticides; Josep, Caixach (I);Xavier, Huguet (I); Jesus, Cabanas (I); *Josep, Rivera (I); Maria Teresa, Galceran (2); Manuel Castro, Carneiro (2);Laboratori d'Espectrometria de Masses, CID-CSIC, Barcelona (SPAIN)

TPD Analysis of Ethylenediaminetetraacetic Acid (EDTA) by Laser Desorption Ion Trap Mass Spectrometry; Kornienko,Oleg; Brynjelsen, Sean; *Hanley, Luke; Orlando, Thomas M. (PNL); University of Illinois at Chicago

TPD Chlorination of Nitrogen-Containing Fragments of Humic Material; *Lebedev, Albert; Moshkarina, Natalia; Buryak,Alexei; Moscow State University

TPD Sample preparation for a mobile GC-MS-System; Matt, Gerhard; *Schillings, Alfred; Harder, Alexander; TechnicalUniversity Hamburg-Harburg

TPD Differentiation ofPAH Structural Isomers by Ion Molecule Reactions with Halogenated Reagent Gases; *Mosi,Andrew; Cullen, WiIliam; Eigendorf, Guenter; University of British Columbia, Department of Chemistry


TPD Ambient Particle Classification Capabilities of Aerosol Time-of-Flight Mass Spectrometry; *Noble, Christopher; Prather,Kimberly; University of California

TPD On-8ite Strategies for Mobile GCIMS Analysis; *NOlke, Birgit; Zey, Thomas; Franzen, Jochen; Bruker-Franzen AnalytikGmbH, Bremen, Germany

TPD Dechlorination Mechanisms of Selected PCB Isomers Containinglsotopically Enriched Chlorine Labels; *O'Brien,Robert T.; Guevremont, Roger; Siu, K.W.M.; Chemical Metrology,lNMS, NRC. Ottawa

TPD Comparison OfPAH Emission Of Standard Diesel, Biodiesel Fuels And Their Blends On Diesel Engine; *Pan, Joseph;Merritt, Patrick; Mclntire, Tom; Sharp, Christopher; "Haines, Howard; Southwest Research Institute, San Antonio, Texas78238

TPD Direct Sampling MS and MS/MS for Real-Time Air Monitoring; *Remigi, Carla; Palmer, Pete; **Karr, Dane; SanFrancisco State University, San Francisco

TPD Low-Voltage Sensitivities for Moleculllr Ion Type Analysis of Fossil-Fuel Distillates; *Scheppele, Stuart; Miller, lames;Research Resources Center, University of llinois Chicago, Chicago, IL

TPD A Solid Scintillation Cell For On-line Metabolite Characterization By Microcolumn LC-RAM-MS; *Schultz, Gary A.;Alexander, lames N.; Rohm and Haas Company, Spring House, PA 19477

TPD Detection ofPAHs in Solid Environmental Samples by Direct Laser Desorption Time-of-Flight MS; Soloveytchik,Boriana; **Dreifuss, Peter A.; *Vertes, Akos; George Washington University, Department of Chemistry

TPD GCMS Analysis of Air Samples and Metal Working Fluids from an Engine Plant; *Subramanian, Periyasamy; Thome,Peter; DeKoster, Jeannine; The Environmental Health Sciences Research Center, University of Iowa

TPD Analysis of Geosmin and 2-Methylisoborneol by Isotope Dilution High Resolution Mass Spectrometry; *Taguchi, Vinee;Jenkins, Steve; Wang, Dave; Palmentier, J-P.; Robinson, Don; Ontario Ministry of Environment and Energy, MassSpectrometry Laboratory

TPD Method Development For Quantifying Chlorinated n-Paraffins by HRGC-ECNIIHRMS.; *Tomy, Gregg; Stem, Gary;Muir, Derek; Westmore, John; Fisk, Aaron; Cymbalisty, Chris; Department of Chemistry, University of Manitoba, Winnipeg,

TPD Analyses of Airborne Species with a Field-Portable Large-Volume Air Sampler Mass Spectrometer; *Wahl, Jon H.;Zemanian, Thomas S.; Robins, William H.; Wright, Bob W.; Pacific Northwest National Laboratory, Richland WA

TPD Comparison of Scanning CCD Array and Point Detection for Small Molecule Analysis; *Wahl, K. L.; Campbell, J. A.;**Finch, J. W.; Miki, S.; Pacific Northwest National Laboratory

TPD Analysis ofPMlO atmospheric partlculates by laser desorption FTIICRlMS; *Xu, Ming; White, Forest; Marshall, Alan;Guan, Shenheng; Dougherty, Ralph; Dept of Chemistry, Florida State University, Tallahassee FL 32306-3006

ORGANIC ANALYSISAbstracts arearranged alphabetically byfirst author

TPE Analysis of Polycyclic Aromatic Hydrocarbons in Meat and Seafood Matrices by SFE/Off-Line GCIHRMSj *Alleyne,Carl S.; Verigin, Victor; Mori, Brian; Health Protection Branch, Health Canada, Bumaby, B.C., Canada V5G 4P2

TPE Proflavine Derivatives for Mass Spectrometrlc Identification in Fish.; *Bencsath, F. Aladar; EISaid, Kathleen; Jester,Edward L. E.; Food and Drug Administration, Gulf Coast Seafood Lab., Dauphin Island, AL

TPE Study ofSesquiterpene Lactones Using Mass Spectrometry; *Campbell, James A.; **Kelsey, Rick G.; Pacific NorthwestNational Laboratory

TPE Negative Ion Cl with an External Source Ion Trap GC/MS for the Analysis of Triglycerides; *Fannin, Steven;**Woffendin, Gary; Conoley, Meredith; Finnigan , Austin TX 78728

TPE GCIMS Chlral Analysis of Enantiomeric Drugs Amenable to GC Separation; *Getek, T.A.; Grill, A.G.; Hua, T.;Hariharan, S.; Bioanalytical R&D, Forest Lab, 220 Sea Lane, Farmingdale, NY 11735

TPE Multispectralldentlfication of Oxidation Products of Glycols and Glycol Ethers; *Green, John Glass; Kao, Jen-Hsiang;The Dow Chemical Company, Louisiana Division, Plaquemine, LA 70765-0400

TPE A Fast GCIMS/MS Method to Quantitate Free Phytosterols; *Jiu Ai, ; Research & Development, UST, 800 HarrisonStreet, Nashvile, TN 37203

TPE Methylamine in Methane: Improved Cl Reagent Gas for Molecular Weight Determinations; *Little, James; EastmanChemical Company, Kingsport, TN

TPE Novel Pyrolysis (PY)-GCIMS Techniques for the Characterization of Additives In Hardened Concrete; *Mabud, Abdul;Jeknavorian, Ara; Barry, E.; Litzau, Jonathan; W.R. Grace & Co, Washington Res. Cent., 7500 Grace Dr., Columbia, MD21044

TPE Identification of a Process Impurity In a Pharmaceutical Raw Material; *Magin, Don; Whitehall-Robins AnalyticalDevelopment, Richmond, VA

TPE TMAH Thermochemolysls/GC-MS Applied to Structural Investigations of Lignin; *Minard, Robert; Dible, Scott;Sewell, Tara; Nanny, Mark; Hatcher, Pat; Penn State University

TPE Quantitative Analysis of Fluorinated Ethylchloroformate Derivatives of Dlpeptldes Using GCIMS; *Moini, Mehdi; Cao,Ping; University ofTexas at Austin, Austin .

TPE A GCIMS and GCIMSIMS Study of Deuterium Exchange in Imlnes; *Organ, Andrew; Thorn, Catriona; Lee, Mike;**Mabon, Ross; SmithKline Beecham Pharmaceuticals, Harlow OK

TPE Volatile Organic Composition In Blueberry; *Overton, Santford V.; Manura, John 1.; Scientific Instrument Services, Inc.,Ringoes, New Jersey 08551

TPE Study of the polymeric part of archaeological adhesives; *Rolando, Christian; Regert, Martine; Menu, Mlchel; Houze,Armelle; Delacotte, Jean-Michel; Ecole Normale Superieure, Departement de Chimle, PARIS (FRANCE)

TPE Rapid Analysis of Volatile Flavor Compounds in Horticultural Produce Using SPME and GCITOFMS; *Song, Jun;Gardner, Ben; Holland, John; Beaudry, Randy M.; Michigan State University


TPE Oxidation of diterpenoid Pinaceae resins in Old Master's paintings.; ·van den Berg, Klaas Jan; Pastorova, Ivana; Spetter,Leo; Boon, Jaap 1.; FOM Institute for Atomic and Molecular Physics, MOLART project

TPE An MSIMS Investigation of Organic Salts; ·Wang, Jia-shen; Clairol Inc., StamfordTPE NEW SILYL DERIVATIVES FOR THE DETERMINATION OF ALCOHOLS BY GCIMS; ·Zaikin, Vladimir;

Shmatko, Michael; "Mikaya, Anzor; Institute of PetrochemicalSynthesis. Leninsky Pr.29, I I79I2,Moscow,RussiaTPE Negative ion chemical ionization/CAD studies ofsome aryl pentafluorobenzoates (part 11);·Zhang, Mei-Yi; Molinary,

Nick; Cantone, Joe; Cingue, Teresa; Chan, Kelvin; Sisenwine, Samuel; Wyeth-Ayerst Research, CN 8000, Princeton, NJ08543

CARBOHYDRATESAbstracts are arranged alphabetically by fust author

TPF MALDI Investigations of Complex Oligosaccharides from Human Milk; .Bahr, Ute; Pfenninger, Anja; Karas, Michael;"Stabl, Bemd; Finke, Bemdt; Sawatzki, Guenther; JW Goethe-Univ., Div. for Instrum. Analyt. Chem., 60590 Frankfurt,Germany

TPF Characterization ofPMP labeled oligosaccharides with MALDI TOF and LC ESI mass spectrometry.; DeBarbieri,Barbara; Ma, Yuemai; Pan, Yu-Ching E.; ·Michel, Hanspeter;Roche Research Center, Hoffinann-La Roche, Inc., Nutley, NJ07110

TPF Methylation Analysis ofOligosaccharides Revisited: CIMSIMS of Permethylated Ethyl-Glycosides; ·Domon, Bruno;Dubreucq, Guy; De Hoffinann, Edmond; Universite des Scienceset Technologies de Lille, Villeneuve d'Ascq, France

TPF Analysis of Complex Sugars in Synthesis; ·Dubay, George; Debenham,John; Rodebaugh, Robert; Fraser-Reid, Bertram;Dept. of Chemistry, Duke University, Durham,NC, 27708-0347

TPF Characterization of a Haemophilus Carbohydrate Epitope Expressed as a Chimeric LPS in E. coli; Gibson, Bradford;·Phillips, Nancy; Engstrom, Jeffrey; "Apicella, Michael; University of California, San Francisco, CA 94143

TPF Synthetic sulfated oligosaccharides: lonspray and MALDI compared; • Jacobs, Peter L.; van Veelen, Peter A.; de Vries,Marcel P.; Dreef, Marijke M.; AKZO Nobel, N.V. Organon, ScientificDev. Group, Oss, The Netherlands

TPF High- and Low-energy Collision -Induced Dissociation ofGlycosphingolipid for Structural Elucidation; ·Kasama,Takeshi; Tadano-Aritomi, Keiko; "Handa, Shizuo; Ishizuka, Ineo; Lab. Biomed. Analysis, Tokyo Medical and DentalUniversity, Tokyo

TPF FABMS (LSIMS), ESIMS and CID-MS/MS, as Guiding Tools in Glycoconjugate Synthesis; ·Kurono, Sadamu; Ohashi,Yoko; Neumann, Klaus; Tamura, Jun-ichi; Ogawa, Tomoya; Nagai, Yoshitaka; The Institute of Physical and ChemicalResearch (RIKEN), Wako-shi

TPF Structural Analysis ofChromophore-Labeled Disaccharides by Liquid ChromatographylMass Spectrometry; ·Li, D.T.;Her, G.R.; Department of Chemistry, National Taiwan University, Taipei, Taiwan, R.O.C.

TPF Derivatized Trisaccharides under LSIMS, MSIMS and MALDI-TOFMS Conditions; ·Perreault, Helene; Costello,Catherine E.; Massachusetts Institute of Technology, Cambridge, MA

TPF Detection of a non-covalent oligosaccharide antigen-antibody complex by ESI mass spectrometry; ·Peter-Katalinic,Jasna; Green, Brian N.; Ashcroft, Alison E.; Narang, Saran A.; Young, N. Martin; MacKenzie, Roger; Altman, Eleonora;Bundle, David R.; Physiological Chemistry, University of Bonn, D-53115 Bonn, Germany

TPF Stabilisation of oligosaccharides containing sialic acids for examination by MALDI; Powell, Andrew; • Harvey,David 1.;Glycobiology Institute, Department of Biochemistry,University of Oxford

TPF Analysis offlavonoids and related phenolics from hops (Humulus lupulus) by HPLC-M8-MS; ·Stevens, Jan F.; Kim,Hoon-Joo; Deinzer, Max L.; Department of Agricultural Chemistry

TPF Multiple Neutral Alkali Halide Attachments onto Oligosaccharides in Electrospray Mass Spectrometry; ·Striegel,Andre M.; Timpa, Judy D.; Piotrowiak, Piotr; Cole, Richard B.; Department of Chemistry, University of New Orleans, NewOrleans, LA 70148

TPF Simple and Rapid Purification of ABDEAE-derivatized Oligosaccharides for the Sensitive MALDI-MS; ·Tambara,Yanet; Takao, Toshifumi; "Fukuda, Hiroyuki; Fukuda, Masafumi; Shimonishi, Yasutsugu; Institute for Protein Research,Osaka University, Suita, Osaka, Japan

TPF N-glycan Structures ofa Small Proteoglycan Decorin; ·Wada, Yoshinao; Nakayama, Yoshiko; Gu, Jianguo; ResearchInstitute for Maternal and Child Health (BOSHI), Osaka, Japan

TPF MALDI-TOF MS of Recombinant E-Selectin and PECAM Oligosaccharides; ·Watson, Eric; Bhide, Anjali; Shah,Bhavana; Karan-Tamir, Barbara; Leidli, Christopher; Lin, Chi-Hwei; Zukowski, Mark; Amgen Inc. Boulder, CO-80301

TPF Sequence Analysis of Heparins by Nitrous Acid Degradation Combined with MALDI Analysis; ·Wolf, Susan; Biemann,Klaus; Massachusetts Institute of Technology

TPF Electrospray Ionization and Collision Induced Dissociation ofOligosaccharides in the Negative Mode; ·Ye, Song;Reinhold, Bruce B.; Reinhold, Vemon N.; Costello, Catherine E.; Boston University Medical School, Boston, MA02118

TPF Highly sensitive structure analysis of oligosaccharides; ·Zhao, Yingming; Qin, Jun; Chait, Brian T; The RockefellerUniversity, 1230 York Avenue, New York, NY 10021

CLINICAL AND BIOMEDICAL MSAbstracts are arranged alp"'abetically by first author

TPG EC-LC-ESI MS: Electrochemisty combined with Liquid Chromatography and Electrospray Ionization MS.;·Baczynskyj, Lubomyr; Structural, Analytical and Medicinal Chemistry, Pharmacia and Upjohn, Inc.

TPG A HPLC-Bioassay-PSD-MALDI Strategy for the Identification of Vasoactive Compounds; Bahr, Ute; ·Karas, Michael;Russ, Thomas; "Schlueter, Hartmut; Luo, Jiankai; JW Goethe-Univ., Div. for Instrum. Analyt. Chem., 60590 Frankfurt,Germany

402 44TH ASMS CONFERENCE ON MASS SPECfROMETRY

TPG Identification of Two Species from the Demethylation ofDerlvatized Free Carnitine in GCIMSIMS; ·Carlson, Shannan;"Borum, Peggy; Johnson, Jodie; Yost, Richard; Department of Chemistry, University of Florida

TPG An enantioselective GC-MS method for the determination ofMilnacipran and its metabolites in plasma; ·Dr. Michaelis,Karl; Agvaz, Ufuk; Zick, Michael; Dr. Schrnid,Bemhard; "Dr. Puozzo, Christian; L.A.B. GmbH, Neu-Ulm, Germany

TPG Mass Spectrometric Analysis of Taxol and Analogues; Emond, Christopher; ·Eigendorf, Guenter; University of BritishColumbia, Department of Chemistry

TPG Identification ofFlavonoid(s) in Wine and Grape Products Implicated in Vasorelaxation Effects; ·Fries, David;O'Malley, Rebecca; "Jantzen, Paul; Fitzpatrick, David; U. South Florida, Dept. of Chemistry-Tampa, FL

TPG Quantitation of (180)- and (13C)-Cholesterollsotopomers by Negative Chemical Ionization GCIMS; ·Hachey, DavidL.; Clarke, Lucinda L.; Liu, Dan; Heird, William C.; Wong, William W.; Baylor College of Medicine, Houston, TX 77030

TPG Trace detection of muramic acid, a bacterial chemical marker, in human body fluids using GC-MS-MS; ·Harrelson,Davis; Fox, Karen; Fox, Alvin; University of South Carolina, School of Medicine, Columbia, South Carolina

TPG Multi-dimensional Analysis of Complex Biological Mixtures Using GCrrOFMS with Time Array Detection; ·Holland,John; Gardner, Ben; Greene, Vaughn; Grainger, James; "Barr, John; Patterson, Don; Michigan State University

TPG Mass Spectrometric Analysis of Morpholino Phosphorodiamidate Oligomers; ·Hudziak, Robert M.; Weller, Doreen L.;Weller, Dwight D.; "Barofsky, Elisabeth; Barofsky, Douglas F.; AntiVirals Inc., 4575 SW Research Way, Suite 200,Corvallis, OR 97333

TPG Identification of Legionella Bacteria using MALDI-TOF for Detection ofPCR Products; ·Hurst, Gregory B.; Doktycz,Mitchel J.; Vass, Arpad A.; Buchanan, Michelle V.; Oak Ridge National Laboratory

TPG Mass Spectrometry and Site-Specific Synthesis of Modified Oligodeoxynucleotides; ·Iden, Charles R.; Department ofPharmacology, University at Stony Brook, Stony Brook, NY

TPG Metal Ion Interactions with Nucleic Acids as Probed by ESI-MS.; ·Ikonomou, M. G.; He, T.; Bertrand, M. J.;Anastassopoulou, J.; Paul, G. J. C.; Institute of Ocean Sciences, Contaminants Science Section, Sidney, B.C.

TPG Analysis ofPorphyrins in Biological Material by Mass Spectrometry.; ·Jones, Russell; Lamb, John; Luo, Jin-Li; Lim,Chang Kee; MRC Toxiology Unit, Leicester, UK

TPG Analysis of Bile Acids by LC/ESIIMS/MS using a Benchtop Quadrupole Ion Trap; •Josephs, Jonathan; Sweeney,Matthew; Gale, David; Sanders, Mark; Finnigan MAT, San Jose CA

TPG Development ofstrategies for Lipid A characterization by methods of mass spectrometry.; ·Kaltashov, lgor; Walker,Kathleen; Doroshenko, Vladimir; Cotter, Robert; Qureshi, Nilofer; Raetz, Christian; Pharmacology, Johns Hopkins UniversityMedical School, Baltimore MD

TPG Structural Elucidation of New Polyether Antibiotics by Tandem Mass Spettrometry; ·Kim, Young Hwan; Yoo, JongShin; Korea Basic Science Institute, Taejon, Korea

TPG The Identification and Characterisation of Bile Acids by LC/ElectrosprayIMS/MS.; ·Lepage, Guy; "Major, Hilary;Hutton McKenna, Therese; Preece, Steve; Hopital Ste-Justine, Universite de Montreal, Montreal, H3T IC5, Canada.

TPG Identification of Degradation Products and Trace Contaminants of Mycophenolic Acid Mofetil by LCMS; ·Lustig,David A.; Roche Bioscience, Palo Alto, CA

TPG Mass Spectrometry of 3,4- and 3,5-Dicaffeoylquinic Acids and Related Analogs; ·Miketova, Petra; Schram, Karl H.;Timmermann, Barbara N.; Liu, Yong-Long; Valcic, Susanne; College of Pharmacy, University of Arizona, Tucson, Arizona85721

TPG Determination ofEDTA and its metal chelates in human blood by ion spray CEIMS; ·Sheppard, Robin; Henion, Jack;Analytical Toxicology, Comell University, Ithaca, NY

TPG Point Mutation Detection by Laser Desorption Mass Spectrometry; ·Taranenko, Nelli; Matteson, Karla; Chung, ChrisNancy; Zhu, Yi-Fei; Chang, L. Y.; AlIman, Steve; Haff, Larry; Martin, Steve; Oak Ridge National Laboratory

TPG Investigation ofthe Production of cADPR and cGDPR by ADP-ribosyl Cyclase using ESI/LCIMS; ·Warrack, BethanneM.; Hail, Mark E.; Green, David W.; Wang, Paulina; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ

TPG Genetic diagnosis with PCR and ESI-MS; Terunuma, Hideya; ·Tsuneyoshi, Toshihiro; Naito, Yasuhiro; Ishikawa,Keiichiro; Koga, Yoshinori; Baba, Shozo; Prockop, Darwin J.; Arakawa, Ryuichi; Shizuoka Inst. of Science and Technology,Fukuroi437,Japan

TPG Structural Elucidation ofC-Glucosyl Chromones from Aloe barbadensis Miller; ·Weintraub, Susan; Salman,Mohammad; Williams, Robert; Hutter, John; Satsangi, Neera; Streeper, Robert; Stavinoha, William; The University of TexasHealth Science Center, San Antonio TX

TPG Factors which affect the reproducibility of pyrolysis mass spectra for microbiological samples; ·Wilkes, Jon G.;"Voorhees, Kent. J.; Rafii, Fatemeh; Sutherland, John B.; Lay, Jackson O.,Jr. ; Freeman, James P.; National Center forToxicological Research, Jefferson, AR 72079-9502

TPG Application of lonSpray Ionization Quantitation Guaifenesin (3-(2-methoxyphenoxy)-I,2-Propanediol); ·Winslow,L.D.; Schomo, Karl S.; Kansas City Analytical Services

TPG Quantitative LCIMSIMS Determination of5-Fluorouracil, Uracil, Tegafur, a.nd Lecucovorin in Plasma; ·Wu, Henry;Henion, Jack; "Kaul, Sanjeev; Wang, Karen; Edom, Richard; Advanced BioAnalytical Services

TPG DNA Sequencing by Laser Induced Fragmentation in MALDI-TOFMS; ·Zhu, Yi-Fei; Taranenko, Nelli; AlIman, Steve;Chen, Chung-Hsuan; Oak Ridge National Laboratory

DRUG METABOLISM - QUANTITATIVE STUDIESAbstracts are arranged alphabetically by first author

TPH Quantitative determination of Lovastatin active metabolite by a new HPLC-negative ion ESIIMS; Abian, Joaquln; Ruiz,Santiago; ·Gelpl, Emilio; Instituto de Investigaciones Biomedicas, IIBB-CSIC, Barcelona


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LCIMSIMS Determination of Bisphosphonates in Human Urinet *Anderson, Melissa; "Lancas, Fernando; Henion, Jack;Anaiytical Toxicology, Corneli University, Ithaca, NY 14850Analysis ofS,9,ll-Triol Eicosatrienoic Acid, A PGHS Derived Urinary Metabolitej *Arora, Vinod; Gamer, Carlos p.;Belas, Frank J.; Blair, lan A.; Vanderbilt University School of MedicineCEIMS-Ion Trap Determination of Bisphosphonates in Human Urinej *Bach, Gloria,; Henion, Jack; AnalyticalToxicology, Corneli University, Ithaca, NY 14850Quantitative Determination ora New Estrogen in Human Serum Using NCI-GCIMSIMSj *Brudny-Kloeppel, Margarete;Baumann, Andreas; Madetzki, Christian; Kuhnz, Wilhelm; Institute of Pharmacokinetics, Schering AG, Berlin, GermanyQuantitative Analysis ofthe PAF Antagonist, SR 27417, in Human Plasma Using LC-MSIMSj *Buhrman, Deborah L.;Price, Piper I.; Drozd, Marion L.; Newton,lohn F.; Herbert, lohn M.; Eliames, George 1.; Rudewicz, Patrick J.; ClinicalPharmacokinetics & Metab., Sanofi Research Division, Malvern, PALow Level Determination of a Novel 4-azasteroid & its Acid Metabolite in Plasma & Semen by LC-MSIMSj .ChavezEng, Cynthia; Constanzer, Marvin; Matuszewski, Bogdan; Carlin, 1.; Graham, D.; Merck Research Laboratories, West PointPA and Rahway, NJQuantitative Analysis of Steroids in Complex Matrices by LCIMSIMS on an Ion Trapt *Cunniff, lack; Tiller, Phillip;Land, Adrian; Vasconcelios, Tom; Wakefield, Mike; Finnigan Mat, San Jose, CA U.S.AQuantitation of 264W94, a Possible Hypocholesteremic Agent, in Rat and Monkey Plasma by LCIMSIMSj *Dunn, John;Otto, Victoria; Kenney, Kathryn; Alisup, Thurman; Marr, Harry; Glaxo Welicome Research Triangle Park, NCIdentification of the urinary metabolite S-NAC-2-ene VPA in patients on VPA therapy using GCIMS; *Gopaul, Sashi;Tang, Wei; Mutlib, Abdul; Farreli, Kevin; Abbott, Frank; University of British Columbia, VancouverMultiple Simultaneous Quantitative LCIMS: A New Tool To Support Drug Candidate Selection; *Hamiiton, Brenda;Abolin, Craig; Sandoz Research Institute, East HanoverQuantitative Drug Metabolism Studies Using LC/CRIMS and LCIESI MSIMS; Hsieh, Feng-Yin; *Goldthwaite, Charles;Yeola, Suresh; Chaudhary, Ajai; Mayol, Robert; Klunk, Lewis; Blair, lan; Vanderbilt University School of Medicine,Nashville, TNMost sensitive quantitative analysis of metformin by LC-MS/MS in human plasma; *Kinzig, Martina; RYsing, Guido;Haag, Armin; Ssrgel, Fritz; IBMP - Inst. f. Biomed. and Pharmaceut. Res., NYrnberg-Heroldsberg, GermanyLCIMSIMS Determination of Carnitine and AcetyIcarnitine in Human Plasma and Urine; *Lowes, Steve; **Bimboeck,Herbert; Henion, lack; Advanced BioAnalytical Services, Ithaca, NY 14850Simultaneous Determination of D-Propylene Glycol Methyl Ether & 2-Methoxypropionic Acid by GClNCIIMS;*McNett, Debra; Hansen, Steven; Bartels, Michael; The Dow Chemical Company, Midland, MlPharmacokinetics and Tissue Distribution of (E,Z)-2,3'-Diene VPA·in the Rat Brain; *Moshenko, lanice L.; Ma, Steven;Abbott, Frank; University of British Columbia, Vancouver, BC, CanadaAutomated SPE in "96 well" microtitre plate format for high throughput bioanalysis using LC-MS-MS; *Pleasance,Stephen; Biddlecombe, Robert A.; Jones, Anne E.; GlaxoWelicomeElectrospray LC-MS/MS for Quantitative Analysis: A Study oflon Suppression; *Rudewicz, Patrick 1.; Vekich, SylviaV.; Luo, Wendy C.; Aliergan, IrvineApplications ofPentafluorobenzyl Chloroformate Derivatization for ECNI / MS; *Simpson, lohn T.; Markey, Sanford P.;National Institute of Mental Health, BethesdaSimultaneous Determination of Steroids in the Low Picogram Range from 1 mL of Serum by LC-MS-MS; *Stuting,Hans H.; "Breau, Alan; Huang, Qingtao; LeBlanc, Yves; Laboratory Corporation of America- Clinical Trials Division,Raritan, NIQuantitation of Pharmaceutical Products using Quadrupole and Ion Trap Mass Speetrometers; *Wakefield, Michael;"Newton,lohn; Burton, Regina; Folk, Brian; Buhrman, Debra; Price, Piper; Wu, Danlin; Land, Adrian; Finnigan MAT Sanlose, CAElucidating the Renal Metabolism of EB 1089, a Vitamin D Analogue, by Capillary LC-ESI-MS; *Weiskopf, Andrew S.;Vouros, Paul; Weinstein, Edward; Siu-Caldera, Mei-Ling; Reddy, G. S.; The Bamett Institute, Northeastern University,Boston, MAQuantitative Determination ofRPR 102681 in Human and Monkey Plasma using Ion Spray LC/MSj *Wu, Henry Y.;Mulvana, Daniel; Henion, lack; "Gilbert, Mary; Advanced BioAnalytical Services, Inc. Ithac, NYLCIMS Quantitation with Electrospray Ionization; *Zhang, Rong; Schoen, Alan; Campbeli, Clay; Finnigan MAT, San lose

LASER DESORPTION - FUNDAMENTALSAbstracts arearrangedalphabetically byfirst authorLaser Desorption Mass Spectrometry from Frozen Water Solutions Using a 3.8 um YAG/OPO Laser System;**Alimpiev, Sergey; Dratz, Edward; *Sunner,lan; Montana State University, Bozeman, MTSurface-Assisted Laser Desorption Ionization from Frozen Water and Organic Solutions; "AHmpiev, Sergey; Chen,Yu-Chie; Shiea, Jen-taie; Dratz, Edward; *Sunner, Jan; Montana State University, Bozeman, MTThe Use of MembraneslFilms and Coated MembraneslFilms in MALDIIMS; *Bai, lian; Liang, Xiaoli; Zhu, Yongdong;Cain, Teresa C.; Lubman, David M.; Department of Chemistry, The University of Michigan, Ann Arbor, MI 48109Characterization of Two New MALDI Matrices; *Bai, lian; Liang, Xiaoli; Liu, Yan-Hui; Zhu, Yongdong; Lubman, DavidM.; Department of Chemistry, The University of Michigan, Ann Arbor, Mich 48109Characterisitcs Of Several New Alpha Substituted Cinnamic Acids As MALDI Matrices; *Brown, Robert; Feng, linhua;Utah State University, Logan, UT 84322-0300Elemental sulfur as a matrix for MALDI-TOF mass spectrometry; *Brune, Daniel C.; Dept. ofChem. & Biochem.,Arizona State University, Tempe AZ 85287-1604


TPI Evaluation of Hydrophobic Interactions of the Matrix and Analyte in MALDI; tCampo, Karen K.; Russell, David H.;Texas A&M University, College Station

TPI Applications ofActivated Carbon Surface Assisted Laser Desorption Ionization (SALDI); tChen, Yu-Chie; Shiea,Jentaie; Sunner, Jan; Montana State University

TPI Surface-Assisted Laser Desorption Ionization (SALDI) Mass Spectrometry from Liquid Solutions; tChen, Yu-Chie;Dratz, Edward; Sunner, Jan; Department of Chemistry and Biochemistry

TPI Effects ofammonium salts as co-matrices for the analysis of oligonucleotides by MALDI; tCheng, S-W.; Chan, T-W.Dominic; The Chinese University of Hong Kong, Hong Kong

TPI Probe Surfaces for Desorption of Bioadive Arrays Tethered with Photolytic Devices; tChing, Jesus; Voivodov, Kamen;Hutchens, T. Willam; University ofCalifornia, Davis

TPI Laser Desorption Mass Spectrometry of PoIynuelear Transition Metal Clusters; tDale, Michael; Dyson, Paul; Johnson,Brian; Langridge-Smith, Patrick; Yates;Hilary; Ferrige, Tony; The University of Edinburgh, Edinburgh

TPI Perrhenate Surface Bombardment in SIMS: Disappearance Cross Sections and Desorption Mechanism; tGroenewold,Gary; Gianotto, Anita; Olson, John; Ingram, Jani; Appelhans, Anthony; Dahl, Dave; Delmore, Jim; Idaho NationalEngineering Laboratory, Idaho Falls, ID

TPI Matrix assisted laser desorption/ionization ofsynthetic polymers with azo-compound matrix; tH. M. Donny , Liu; Urs.P., Schlunegger; Institute of Organic Chemistry, University of Bern, Bem! Switzerland

TPI Chemical and Physical Processes in Aerosol MALDI; tHe, Lin; Wei, Gang; Murray, Kermit; Emory University, AtlantaTPI Frozen Liquid Matrices for MALDI Time-of-Flight Mass Spectrometry of DNA Oligomers; tHunter, Joanna M.; Lin,

Hua; ttBecker, Christopher H.; SRI International, Menlo Park, CA 94025TPI MALDI of Individual Size.Selected Micropartieles; t Johnston, Murray; Mansoori, Bashir; University of Delaware, Newark,

DETPI Studies on the selection of new matrices for UV Matrix-Assisted Laser Desorptionllonization MS; tKrause, Joern L.;

Schlunegger, Urs P.; Department of Organic Chemistry, University of Berne, Berne, SwitzerlandTPI Fragmentation of Suifated Dyes, Drugs and Sugars Desorbed as Noncovalent Complexes upon MALDI; tRhomberg,

Andrew; Biemann, Klaus; Massachusetts Institute of TechnologyTPI Polyphenolic Compounds as New MALDI Matrices; tSumner, L10yd W.; Shields, Sharon J.; Wolf, Barbara P. ; Russell,

David H.; Texas A&M Univ., Laboratory for Biological Mass Spec., College Station, TXTPI Comparing SIMS with Laser DesorptionlPhotoionization for Molecular Surface Analysis; Trevor, Jennifer L.; tHanley,

Luke; Lykke, Keith R.; ttPellin, Michael 1.;University of Illinois at ChicagoTPI Off-line coupling ofCE and MALDI MS: Continuous sample deposition on a matrlx-preenated membrane; tZhang,

Haiying; Caprioli, Richard; University of Texas Medical School, Houston, Texas 77030TPI Detection of DNA by MALDIIMS: Sample preparation-purification of DNA samples; tZhu, Yongdong; Bai, Jian; Liu,

Yian-hui; Liang, Xiaoli; Lubman, David M.; Dept. of Chem. The Univ. ofMich. Ann Arbor, M148I09-I055

SPRAY IONIZATION - APPLICATIONSAbstracts arearranged alphabetically byflrst author

TPJ Photolysis of Coordinated Diamine in Bis(1,1'-bipyridine) Complexes of Ruthenium using On-Line ES-MS; t Arakawa,Ryuichi; Mimura, Shin-ichi; Matsubayashi, Gen-etsu; Matsuo, Takekiyo; Department of Applied Chemistry, Osaka University

TPJ Techniques for Automated Molecular Weight Measurements Using Electrospray Ionization MS; tCovey, Tom; McLean,Matt; Liu, Charles; Bonner, Ron; Burton, Lyle; SCIEX, Concord, Canada

TPJ Analysis of Transition Metal Picolinate Complexes by Electrospray LCIMS, GCIMS, and ICP-AES; tFlurer, Rick;Mulligan, Kevin; Bames, Barbara; Satzger, Duane; Forensic Chemistry Center, U.S. FDA, Cincinnati, OH

TPJ Accurate mass determination of agrochemicals and their metabolites using APCIIMS; tFujiwara, Hideji; MonsantoCompany, S1. Louis, Missouri

TPJ Electrospray Mass Spectrometry of Borane Salts: Maximum Results with Minimal Effort; tHop, Comelis E.C.A.;Gaines, Donald F.; Saulys, Dovas A.; Chemistry Department, University of Wisconsin-Madison, Madison, WI

TPJ Analytical Strategies for Rapid Molecular Formula Determination Using High Resolution ESI MS; tKlohr, Steven;Whitney, Jeffrey; Rourick, Robyn; Volk, Kevin; Muenster, Helmut; Kerns, Edward; "Lee, Mike; Bristol-Myers Squibb,Wallingford, CT 06492

TPJ FT-ICR studies ofsandwich-type (phthalocyaninato)(porphyrinato)Lanthanide(1I1) complexes using ESI; tLau,Rebecca L.C.; Ng, Dennis K.P.; Chan, T-W. Dominic; The Chinese University of Hong Kong, Hong Kong

TPJ The use of IS-MS in the characterization of metallothioneins; tLe Blanc, J.C. Yves; "Blais, Jean-Simon; PE-Sciex, 71Four Valley Drive, Concord (Ontario) L4K 4V8, Canada

TPJ Analyses of Cu(l) Complexes via ESI Mass Spectrometry: Implications for Organocuprate Reagents; Lipshutz, BruceH.; James, Brian; tStevens, Kirk L.; Pavlovich, James G.; University of California Santa Barbara

TPJ Accurate Mass ESI on a Magnetic Sector Mass Spectrometer; tMoore, Colin; Uniroyal Chemical Company, Inc.,TPJ EIectrospray Fourier Transform Mass Spectrometry for the Analysis of Biopolymers; to'Connor, Peter B.; Duursma,

Marc C.; Heeren, Ron M.A.; Boon, Jaap J.; FOM Institute for Atomic and Molecular physicsTPJ A Comparison of Quadrupole, Sectors and Ion-Trap Analysers to Ascertain Multicharged-Ions Assigments; tPicard,

CIaudine; Uzabiaga, Francoise; Petitou, Maurice; Picard, Claude; Galaup, Chantal; "Porter, Chris; Sanders, Mark; Pugh,Jonathan; Sanofi Recherche and CNRS URA 471 Toulouse France

TPJ ESIIMS of Organometallic Compounds on an LCIMSIMS Ion Trap Mass Spectrometer; tSweeney, Matt; Josephs,Jonathan; Gale, David; Sanders, Mark; Finnigan MAT, 355 River Oaks Parkway, San Jose CA, 95134

TPJ Electrospray Ionization Mass Spectrometric Analysis ofOxo-Bridged Manganese Dimers; tWeintraub, Susan; Ciringh,Yangzhen; Horwitz, Colin; The University ofTexas Health Science Center, San Antonio TX

PRELIMINARY PROGRAM

TPJ ESI-MS of Organometallic Compounds; *Wolf, Barbara P.; Shields, Sharon J. ; Sumner, L10yd W.; Russell, David H.;Texas A&M Univ., Lab. for Biological Mass Spectrometry, College Station, TX

TPJ Accurate mass and MSIMS analyses of CombInatorIal Chemistry products by Micro Electrospray; *Woolfitt, A. R.;Bateman, R. H.; Green, M. R.; Ordsmith, N. H. R.; Pugh, D.1.; VG Organic, Manchester, M23 9LZ, UK

DNAlRNA STRUCTURE & ADDUCTSAbstracts arearranged alphabetically byfirst author

405

TPK The Effect of Backbone Charge on the Collision-Induced Dissociation of Ollgonucleotldcs; *Bartlett, Michael;McCloskey, James; Griffey, Richard; Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT

TPK Analysis of Oligonucleotides Bound to Positively Charged Surfaces; *Bruenner, Bernd; Hutchens, T. William; Universityof California, Davis Davis

TPK Drug-DNA Interaction Studies Using Electrospray Ionization Mass Spectrometry; *Gao, Quanyin; Cheng, Xueheng;Smith, Richard D.; "Yang, Catherin F.; Goldberg, Irving H.; Pacific Northwest National Laboratory

TPK Electrophore Mass Labels for TOF-MS DNA Sequencing; *Giese, R.; Xu, L., Wang, P.; Bian, N., Abushamaa, H.; Wang,Z., Magiera, D.; Murugaiah, V., Pillai, S.; Laukien, F., Park, M. 1-2; Church, G., Kutney, L. 1-3; Smith, D., Carson, S. 1-4;Northeastern Univ., Bruker Instrum., Harvard Med. Sch., Genome Therapeutics

TPK HPLC and ESI Mass Spectrometric Sequencing of Three Methyl-oligonucleotides; Glover, Robert P.; *Sweetman, GavainM.A.; MRC Toxicology Unit, Leicester, UK

TPK Correlation between ES-MS charge states for oligonucleotides and solution counterion condensation; *Griffey, Richard;Greig, Michael; Sasmor, Henri; Isis Pharmaceuticals, Carlsbad, CA

TPK Metal(lI) Ion Complexes of ACC Formed by Electrospray Ionization; *Hamilton, JiII; Adams, Jeanette; Department ofChemistry, Emory University, Atlanta, GA 30322

TPK Gas-Phase Chemistry of Metal(11) Ion Complexes of Trinucleotides; *Hamilton, Jill; Adams, Jeanette; Department ofChemistry, Emory University, Atlanta, GA 30322

TPK LCIESI MS/MS assay for 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-oxo-dG); *Kowalski, E.M.; Chaudhary, A.K.; Blair,LA; Vanderbilt University, Nashville TN

TPK Chemical Sequencing of Oligonucleotides with Modified Backbones Using Mass Spectrometry; Polo, Lenore M.;McCarley, Tracy D.; *Limbach, Patrick A.; Louisiana State University, Baton Rouge, LA 70803

TPK Detection of Non Covalent Interactions in Nucleic Acids using MALDI; *Lecchi, Paolo; Garland, Carl; Howard, Frank;Miles, Todd; Pannell, Lewis; Laboratory of Analytical Chemistry, NIDDK, NIH, Bethesda, MD 20892-0805

TPK Mass Spectrometric Methods for Genotyping; *Little, Daniel P.; Higgins, G. Scott; Braun, Andreas; Darnhofer, Brigitte;Leppin, Lorieta; Craven, Fiona; Koster, Hubert; Sequenom Instruments GmbH

TPK Analysis of Oligonucleotide Mixtures by ESI-MS Utilizing Charge-State Reduction; *Muddiman, David C.; Bruce, JamesE.; Pasa-Tolic, Ljiljana; Smith, Richard D.; Pacific Northwest National Laboratory

TPK Further Investigation of Alkali Metal Ion Interactions with Nucleosides by LSIMS; *Paul, G. J. C.; Ikonomou, M. G.;Anastassopoulou, J.; Bertrand, M. J.; University of Montreal, Montreal

TPK GC/ECNCIIMSIMS Analysis of Elctrophore-Iabeled DNA Adducts; *Ranasinghe, Asoka; Scheller, Nova; Wu, Kuen;Swenberg, James; University of North Carolina at Chapel Hill

TPK Reduced Cation Adduction in Negative Ion ESI Mass Spectra ofOligodeoxynucleotides; *Rieger, Robert A.; Iden,Charles R.; Department of Pharmacology, University at Stony Brook, Stony Brook, NY

TPK Characterization by MALDI-TOFMS side-products in oligodeoxynucleotide synthesis; *Wang, Bing; Budman, Eva;Belenky, Alexei; Froim, Doriana; Cohen, Aharon; Hybridon, Inc.

TPK Characterization of Modified Oligonucleotides by Enzymatic Digestion and Ionspray Mass Spectrometry; *Wu,Huaiqin; Morgan, Ronald; Aboleneen, Hoda; Abbott Laboratories, Diagnostics Division, Abbott Park, IL60064

TPK Optimization of Enzymatic Sequencing ofOligonucleotides with Ionspray Mass Spectrometry; *Wu, Huaiqin; Chan,Clifford; Aboleneen, Hoda; Abbott Laboratories, Diagnostics Division, Abbott Park, 11 60064

TPK Synthesis of IJC5-adenine and UC5-2'-deoxyadenosine for mass spectrometric studies of DNA-adducts; *Yeola, S. N.;Saleh, S. A.; Chaudhary, A K.; Blair, L A; Vanderbilt University, Departments of Chemistry and Pharmacology

TPK Trace Detection ofElectrophores by EC-FTMS; *Zhang, Tianlan; Van Orden, Steven; Laukien, Frank; Huang, Yulin; Giese, Roger; North Eastern University, Boston, MA


TPL Isotopic differences in human growth hormone preparations; *Abramson, Fred; Osborn, Blaire; Teffera, Yohannes;George Washington University, Washington, DC

TPL Binding ofCu(lI) in Doubly Charged Ions of Angiotensin 11 Formed by Electrospray Ionization; *Adams, Jeanette;Sullards, Cameron; Department of Chemistry, Emory University, Atlanta, GA 30322

TPL Hemorphin metabolism in blood and brain studied by microdialysis/electrospray mass spectrometry; *Andren, Per E.;Sanderson, Katarina; Nyberg, Fred; Dept. of Pharm. Biosciences, Uppsala University, Uppsala, Sweden

TPL High Sensitivity Identification of Proteins from SDS PAGE using In-Gel Digestion and MALDI-PSD; *Annan, Roland;McNulty, Dean; Carr, Steven; SmithKline Beecham Pharmaceuticals

TPL Protein Identification on 2D Gels by Image Analysis, CaplJlary LC-MS and Tandem MS: Applications; *Amott, David;Stults, John; Genentech, Inc., South San Francisco, CA 94080

TPL MALDI and ESI MS to study binding sites for phenothiazine inhibitors oftrypanothlone reductase; Bolgar, Mark S.;*Itoh, Shinji; Gaskell, Simon J.; Yin, Hong; Chan, Cecil; Garforth, Jacqui; **Douglas, Kenneth T.; Fairlamb, Alan H.;Michael Barber Centre for Mass Spectrometry, UMIST, Manchester, U.K.


TPL Regiospecific binding ofPAH metabolites to albumin: screening and characterization by LC-MSIMS.; ·Brunmark, Per;Skipper, Paul L.; Tannenbaum, Steven R.; Wishnok, John S.; Massachusetts Institute ofTechnology, Cambridge, MA

TPL Analysis of Dacteriorhodpsin Cleavage Fragments by HPLC-ESI-MS and MS/MS; ·Busman, Mark; Cowden, Lori B.;Knapp, Daniel R.; Dept. of Pharmacology, Medical Univ. of South Carolina, Charleston, SC

TPL Electrospray Ionisation Mass Spectrometry Study of FOInhibitors Interactions with Ceroid Lipofuscin; Buzy, Annelle;Ryan, Edward M.; Griffiths, David E.; • Jennings, Keith R.; University of Warwick, Department ofChemistry, Coventry CV47AL,UK

TPL Monitoring Enzymatic Reactions by Mass Spectrometry; Chavez, Rodrigo; Bothner, Brian; Strupp, Christian; Hilvert,Don; ·Siuzdak, Gary; The Scripps Research Institute, La Jolla, California

TPL The charge remote loss of60 Da from peptides containing an arginine residue at the C-terminus.; ·Deery, Michael J;Summerfield, Scott G; Buzy, Armelle; Jennings, Keith R; Department of Chemistry, University of Warwick, Coventry CV47AL, U.K.

TPL An unusual fragmentation pattern in the determination of the sequence of a cyclic peptide; Domingues, Pedro; • FerrerCorreia, A.J.V.; Mass Spectrometry Laboratory, Chemistry Dep., Aveiro University, Portugal

TPL High Sensitivity MSIMS and MALDI on a Tandem 4-Sector Instrument with a Scanning CCD Array Detector; ·Finch,Jeffrey W.; Miki, S.; Koli, V.S. Kumar; He, Shou Ming; Orlando, Ron; JEOL USA Inc., 11 Dearborn Rd., Peabody, MA01960

TPL Novel Derivatization Schemes For Collisional Activation Spectra Of Peptides; ·Gedamke, Rich; Hail, Mark; DiDonato,Gerald; Lee, Mike; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ

TPL Interpretation of peptide fragment ion intensities for a series of D- and L- amino acid isomers; ·Goodlett, David R.;Gale, David C.; "Crowther, Jonathan 8.; Mukherjee, Tarit; Goodlett Scientific, Seattle WA

TPL Selective Sulfur-bond Cleavage in the Low-Energy CID of Disulfide Linked Peptides; ·Haller, Ivan; Chait, Brian T.; TheRockefeller University, New York, NY 10021

TPL Simplified MALDI-TOF peptide sequencing by combined Post Source Decay (PSD) and ladder analysis; ·Hauer,Charles R.; "Kowalski, Paul; Roth, Karen; Stack, Robert; Wadsworth Center

TPL Examination of Metallothionein Isoforms in Drug Resistant Human Bladder Tumor Cells.; ·He, Tao; "Hilton, John;Zaia, Joseph; Fabris, Daniele; Fenselau, Catherine; University of Maryland Baltimore County, Baltimore, MD

TPL Mass Spectrometric Characterization of Protein-Isocyanate Conjugates by Electrospray Ionization; ·Hesso, Antti;Tornaeus, Jarkko; Pfaeffii, Pirkko; Vainio, Harri; Finnish Institute of Occupational Health, Helsinki, Finland

TPL LC-ESIMS and MALDI-TOFMS Peptide Mapping ofthe Tetanus Toxin C Fragment; ·Hines, Harry; Brueggermann,Ernst; "Sumpter, Terry; Toxinology Division, USAMRlID, Ft. Detric, Frederick, MD

TPL Structure Elucidation of Oa(Phytochrome A; •Jiang, Xiangyu; Lapko, Veniamin; Song ,Pill-Soon; Smith, David;Department of Chemistry, University of Nebraska, Lincoln, NE68588

TPL Electrospray Ionization Mass Spectrometry in Discovery of Scorpion Venom Neuropeptide Toxins; ·Jones, A. Daniel;Lehmberg, Elisabeth; Moskowitz, Haim; Herrrnann, Rafael; Nakagawa, Yoshiaki; Hammock, Bruce D.; University ofCalifornia - Davis, Davis CA

TPL Does MS/MS always identify the modification sites in peptides?; ·Katta, Viswanatham ; Rohde, Michael F.; Amgen Inc,Thousand Oaks, CA-9l320

TPL LC-MS, CZE-MS and LC-MSIMS investigation of protein tyrosine phosphatase inhibition by pervanadate; ·Kelly,John; Huyer, Gregory; Ramachandran, Chidambaram; Kennedy, Brian; Merck Frosst Centre for Therapeutic Research,Kirkland, Qu bee, Canada

TPL CID of derivatized peptides analyzed on a sector instrument equipped with an orthogonal TOF analyzer; ·Lindh,Ingemar; Griffiths, WiIliam J.; Bergman, Tomas; Sjovall, Jan; Karolinska Institutet, Stockholm, Sweden

TPL Sequencing isobaric peptides by the application of MSn analysis on an ion-trap mass spectrometer; ·Maleknia, Simin;Corixa Corporation. 1124 Columbia Street, Seattle, WA 98104

TPL Protein Sequence and Structural Studies Employing MALDI-High Energy Collision-Induced Dissociation;·Medzihradszky, Katalin; Yu, Zhonghua; Hall, Steven; Maltby, David; Burlingame, Alma; Mass Spectrometry Facility,University of California, San Francisco

TPL Characterization of Proteins Isolated from Cell Nuclei Using MALDI TOF MS and PSD Analysis; ·Murphy, Constance;Nilsson, Carol; Ekman, Rolf; Department of Neurochemistry, University of Goteborg, Molndal, Sweden

TPL Fully Stable-Isotope Labeled Proteins: New Techniques for Production and PKlPD Studies Using CRIMS; ·Osborn,Blaire L.; Abramson, Fred P.; George Washington University

TPL Using high- and low-energy CID MSIMS data to identify and characterize an unnatural amino acid; .Papayannopoulos,Ioannis A.; Biogen Inc., Cambridge, MA

TPL Structure elucidation of glutathione and related thiols by FAD, ESI and NICI mass spectrometry; ·Ramanathan,Ragulan; Byun, Jaeman; Hsu, Fong; Gross, Michael; Cao, Kai; Cavalieri, Ercole; Washington University, Department ofChemistry, St. Louis, MO 63130

TPL Electrospray Tandem MS for Amino Acid Sequence Determination of Antineoplastic Peptides.; ·Roboz, John; Wang,Tsonghui; Ma, Long Hua; The Mount Sinai School of Medicine, New York, NY 10029

TPL A Study of Side-chain Involvement in CAD oftris(Trimethoxyphenyl)phosphonium-Derivatized Peptides; .Roth,Kenneth; Huang, Z.-H.; Watson, J. Throck; Michigan State University, East Lansing, MI 48824

TPL Characterization of a hirudin beta-aspartyl isoform by low energy CID; ·Schindler, P.; MYller, D.; Grossenbacher, H.;MSrki, W.; Richter, W. J.; Central Research Services Ciba-Geigy Ltd., CH-4002 Basel

TPL HPLC-ESIMS in the quantitation of endothelins in cell culture medium and organ tissue; Schneider, Klaus; VanLeeuwen, Stefan; Peralta, Carmen; Canosa, Daniel; Abian, Joaquin; ·Gelpi, Emilio; Instituto de Investigaciones Biomedicas.IlBB-CSIC, Barcelona


TPL The observation of d-type ions during the low energy CID of protonated peptides; ·Summerfield, Scott G.; Cox,Kathleeen A; Gaskell, Simon J.; Michael Barber Centre for Mass Spectrometry, UMIST, Manchester, UK

TPL Structural characterization of the Dloelea drandiflora seed lectin using MALDI-MS, LC-MS and MS-MS; ·Tang, Xuejun; Swamy, Bale M.; Brewer, C. Fred; Albert Einstein College of Medicine

TPL Identification of proteolytic fragments of peptide hormones by HPLC-ESI-MS and HPLC-ESI-MS-MS; .Treston,Anthony; ··Snider, Richard; Nylen, Eric; Kelley, Michael; Becker, Kenneth; BPRB, National Cancer Institute, RockviIle MD20850·3300

TPL Characterization ,nd quantification of opioid peptide analogs in sheep plasma by capillary LCIMSIMS; ·Tseng, JihLie; Grigoriants, U.; Yan, Lin; Desiderio, D. M.; Deptments of Neurology and Biochemistry, University ofTenessee,Memphis

TPL Novel Peptide Dissociation: Gas Phase Intramolecular Rearrangement of Internal Amino Acid Residues; .Vachet,Richard W.; Bishop, Bamey M.; Erickson, Bruce W.; Glish, Gary L.; University of North Carolina, Chapel Hill

TPL MS-MS characterization ofthe bradykinin peptide fragments RPP, RPPG and RPPGF.; ·Vrbanac, James; Pharmacia &Upjohn, Inc., Kalamazoo, Michigan

TPL Surface-Induced Dissociation of Disulfide-Containing Peptides; ·Zhong, Wenqing; Wysocki, Vicki; VirginiaCommonwealth University

WEDNESDAY POSTERS

ION SOURCE AND MS INSTRUMENTATIONAbstracts are arrangedalphabetically byfirst author

WPA Time-of-Flight Mass Spectrometer System as a Detector for High Speed Gas Chromatography; ·Artaev, Viatcheslav B.;Parry, Ritchard; Phinney, Mary Jane; Mitchell, Joel; LECO Corporation, St. Joseph

WPA Automated recording ofMALDI MS and high energy CID MS/MS spectra on a tandem magnetic sector-TOF;·Bateman, R. H.; Davis, T.; Green, M. R.; Kingston, R. G.; VG Organic, Manchester, M23 9LZ, UK

WPA Automatic recording of LC-MS & LC-MS-MS spectra on a tandem magnetic sector-TOF with magnet bypass.;Bateman, R. H.; Davis, T.; Green, M. R.; Ordsmith, N. H. R.; Pugh, D. J.; ·Woolfitt, A R.; VG Organic, Manchester, M239LZ, UK

WPA A New Generation MALDI TOF Tandem Mass Spectrometer; ·Brinkmalm, Gunnar; Westman, Ann; Gafken, Phil;Barofsky, Douglas F.; Dept. Ag. Chem., Oregon State Univ., 1007 ALS, Corvallis, OR 97331-7301

WPA Convergence of Spatially Dispersed Ion Beams from Ion Mirrors; ·Constantopoulos, Terri L.; Erickson, Tina A; Ji,Qinchung; Enke, Christie G.; University of New Mexico, Albuquerque, NM 87131

WPA Tandem TOF Mass Spectrometry: Applications to FulIerenes and Metal-Phthalocyanines.; ·Cordero, M.M.; Cornish,T.J.; Cotter, R.J.; Pharmacology, Johns Hopkins University Medical School, Baltimore MD

WPA A High Speed, High Voltage Analog Switch with Precise Timing Control for An Ion Trap-TOF MS; ·Davenport,Michael R.; Holland, John F. ; Ji, Qinchung; Enke, Christie G.; Dept. of Chemistry, University of New Mexico, Albuquerque,NM

WPA A Theoretical and Practical Description ofan Interleaved-Comb Ion Deflection Gate; ·Erickson, Tina; Beussman,Douglas; Enke, Christie; University of New Mexico, Albuquerque

WPA Ion Isolation and Kinetic Energy Analysis in TOF Mass Spectrometry using a Two-section EPG; ·Hanson, Curtiss D.;Adams, Nathan; Page, Jason; Just, Craig; University of Northern Iowa

WPA A Proposed Two Dimensional QuadrupolelElectrostatic Ion Trap Time-of-Flight Mass Spectrometer; ·Ijames, Carl F.;National Institute of Mental Health, Bethesda

WPA Time-of-Flight Mass Spectrometry Analysis of Trapped Ions Generated by Electron Impact Ionization; ·Ji, Qinchung;Holland, John F.; Davenport, Michael R.; Enke, Christie G.; Department of Chemistry, University of New Mexico

WPA A Transmission Geometry Probe for MALDI; ·Lennon, Ill, John D.; Glish, Gary L.; University of North Carolina atChapel Hill, Chapel Hill

WPA MSIMS ofall precursor ions in one shot and MS' capability by 2-0 /3-0 DEF-TOF; ·Linden, H. Bernhard; Bamberg,Michael; Linden ChroMasSpec GmbH, Auf dem Berge 25, 0-28844 Leeste, Germany

WPA Magnetic sector/time-of-flight combination for tandem analysis of MALDI ions using high-energy CID; ·Raptakis,Emmanuel N.; Makarov, Alexander A.; Colburn, Alex W.; Derrick, Peter J.; University of Warwick

WPA High Resolution Reflectron Time-of-Flight Mass Spectrometer; ·Reents, William; AT&T Bell LaboratoriesWPA A new tandem quadrupole mass filter and othogonal acceleration TOF MSIMS configuration.; Bateman, R. H.; Bordoli,

R. S.; Gilbert, A J.; ·Hoyes, J. B.; ··Morris, H. R.; VG Organic, Manchester, M23 9LZ, UKWPA Mass Resolution Improvement in MALDI-TOF Mass Spectrometry by Pulsed Ion Extraction; Zhang, Wenzbu; ·Niu,

Shufang; Chait, Brian T. ; The Rockefeller University, 1230 York Avenue, New York, New York 10021

FUNDAMENTAL STUDIESAbstractsare arrangedalphabetically byfirst author

WPB Beam-induced redox processes for the methylene blue/thioglycerol system in LSIMS.; • Allard, Martine; Bertrand, Michel,J.; University of Montreal, Montreal

WPB Determination of proton affinities by comparison of the abundances of ions formed under FAD; ·Amado, Francisco M.L.; Santana-Marques, M. Gra a 0.; Ferrer- Correia, A J. V.; Department of Chemistry, University of Aveiro, 3810 Aveiro,Portugal

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Proton Affinities ofMALDI Matrices; Burton, Richard D.; Watson, Clifford H.; Eyler, John R.; Lang, G. Lisa; Avery,Marcella Y.; *Powell, David H.; University of Florida, Gainesville, FLConditions in favor of a linear dependence of analyte ion signals on concentration in FAB MS; Klesper, Gunter; Plltzold,Sabine; Mertens, Christian; *ROlIgen, Franz W.; lost. of Physical Chemistry, University of Bonn .Secondary ions and electrons in MALDI: Desorption and Detection; *Knochenmuss, Richard; Dubois, Fr d ric; Zenobi,Renato; LOC, ETH ZYrich, ZYrich SwitzerlandStudy of the processes of cryobiological interest by means of low temperature FAB mass spectrometry; *Kosevich,Marina; Shelkovsky, Vadim; Boryak, Oleg; Institute for Low Temperature Physics and Engineering NAS UkraineLaser-stimulated Matrix to Analyte Proton Transfer in Clusters; *Land, C. Mark; Kinsel, Gary R.; Dept. of Chemistry,The University ofTexas at Arlington, Arlington, TXStudies ofMALDI Matrix Proton Affinities by FT-ICRMS; *Li, Nan; Kinsel, Gary R.; Dept. of Chemistry, The UniversityofTexas at Arlington, Arlington, TX .Study of the Behavior ofa Series of Quaternary Ammonium Bromides under Positive and Negative LSIMS; *Marcotte,I.; Paul, G. 1. C.; Anastassopoulou, J.; Bertrand, M. J.; University of Montreal, MontrealFactors Influencing the Clustering of Quaternary Ammonium Bromides in LSIMS; *Marcotte, I.; Paul, G. J. C.;Anastassopoulou, J.; Bertrand, M. 1.; University of Montreal, MontrealPrimary Ion Dosimetry; *McMahon, John M.; McCandlish, Carl A.; Todd, Peter J.; Oak Ridge National Laboratory, OakRidge, TennesseeCluster and Cluster Ion Formation from Organic Molecules Investigated by Multiphoton Ionization; Meffert, Anja;*Moritz, Fritz; Schied, Thomas; Grotemeyer, JUrgen; Institut fur Physikalische Chemie, Universitllt WOrzburgAn Investigation of the Ionization Mechanism in LSIMS for Cis-Stilbene Oxide; *Obarewicz, Stephan; **Paul, Gary J. c.;Bertrand, Michel J.; University of Montreal, Montreal.Formation of hydrate clusters under low temperature fast atom bombardment conditions; *Shelkovsky, Vadim;Kosevich, Marina; Boryak, Oleg; Stepanov, Igor; Institute for Low Temperature Physcis and Engineering NAS UkraineIon Yields from Matrix Surface Bombarded with 6 keY Xe, Ar, He, Air, and Isobutane Beams; *Takayama, Mitsuo;Pharm. ScL, Toho Univ., 2-2-1 Miyama, Funabashi, Chiba 274, JapanFactors Influencing Nucleic Acid Analysis in MALDI:Fragmentation, Positive-Ion, and Mixture Analyss; *Tang, Wei;Zhu, Lin; Nelson, Christine; Smith, L1oyd; Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706Matrix Properties derived from the LSIMS Spectra of the Pure Matrices and Surface Tension Effects; *Theberge,Roger; Paul, Gary; Bertrand, Michel; Regional Center for Mass spectrometry, MontrealCoincidence TOF-MS: An Alternative to MS/MS for Multi-Component Sample Analysis; *Van Stipdonk, Mike; English,Robert; Schweikert, Emile; Department of Chemistry, Texas A&M University, College Station, TexasMetal-Binding Properties ofa New Hexahomotriazacalix(3)arene by Electrospray-MS/MS; *Znamirovschi, Calin; Wu,Si; Hampton, Philip; Enke, Christie; Department of Chemistry, University ofNew Mexico, Albuquerque, NM 87131Contribution of chunk ejection to molecular ion formation in PDMS and SIMS; *Zubarev, Roman; Demirev, Plamen;Hffikansson, Per; Abeywarna, Udaya; Sundqvist, Bo U. R.; Uppsala university, Sweden

ISOTOPE RATIOS, INORGANIC & ELEMENTAL ANALYSISAbstracts are arranged alphabetically by first author

Reduced Space Charge Effects in ICPIMS by Selective Elimination of Argon Matrix Ions; *Barinaga, Charles; Eiden,Gregory; Koppenaal, David; Pacific Northwest National Laboratory"Organometallic Speciation and Elemental Quantification Using Gas Chromatography/Mass Spectrometry; *Barshick,Christopher, M.; Lake, Derek, A.; Barshick, Stacy-Ann; Mohill, Matthew, L.; Britt, Phillip, F.; Oak Ridge National LaboratoryDetermination of trace elements in polysilicates by ID-ICP-MS with USN/membrane desolvation; *Bonchin-Cleland,Sandra; Olivares, Jose; Los Alamos National Laboratory, Los Alamos NMInorganic Composition Analysis of Coal Surface with High Performance Secondary Ion MS; *Brozolo, Fillippo; Liang,Handong; Re, Deyi; Mao, Helin; China University of Mining & TechnologyPreliminary Figures of Merit of a Plasma Source Mass Spectrograph; *Burgoyne, Thomas; Hieftje, Gary; Hites, Ronald;Indiana University, Bloomington, IN 47405Tandem Mass Spectrometry of Polyruthenium Clusters using a Hybrid Sector/Orthogonal Acceleration TOF; *Curtis,Jonathan M.; Chan, Kenneth RN.; **Blenkiron, Peter; Carty, Arthur J.; Institute for Marine Biosciences, N.R.C., Halifax,Nova Scotia, CanadaHigh Resolution and High Abundance Sensitivity Quadrupole ICP-MS; *Douglas, Don; Ying, Ji-Feng; University ofBritish ColumbiaDesign and properties of a laser ablation/ICP-MS for bulk analysis and geological applications; Douthitt, Chuck; Greb,Ulrich; Hamester, Meike; Rottmann, Lothar; *Schroeder, Emst; Finnigan MAT GmbH, Barkhausenstr.2, D-28197 Bremen,Germany.Determination of elements of pharmaceutical interest in biological samples ~f human origin by ICP-MS; *Dr. Michaelis,Karl; Dr. Schmid, Bemhard; Deseyve , Ewald; LAB. GmbH, Neu-Ulm, GermanyRecent Improvements in a High-Efficiency Thermal Ionization Cavity Source for Mass Spectrometry; *Duan, Yixiang;Olivares, Jose; Los Alamos National Laboratory, CST-9, MS J514, Los Alamos, NM, 87545.Selective elimination ofargon ions in an inductively coupled plasma-ion trap mass spectrometer; *Eiden, Gregory;Barinaga, Charles; Koppenaal, David; Pacific Northwest National Laboratory*Elemental and Isotopic Analysis of Geological and Environmental Samples Using an ICP-ITMS; *Frum, C.I.; Universityof Nevada, Las Vegas IHRC, Las Vegas, NV 89154


WPC On-Line Kryton and Xenon Isotopic Analysis by Microwave Plasma Ionization Ion Trap MS; *Garrett, Aaron; Yixiang,Duan; Olivares, Jose; Hemberger, Philip; Los Alamos National Laboratory, Los Alamos, NM

WPC Advances & applications ofresonant laser ablation - quadrupole ion trap mass spectrometry; *GiII, C. G.; Garrett, A.W.; Earl, W. L. ; Hemberger, P. H. ; Nogar, N. S. ; Los Alamos National Laboratory

WPC Mass Spectrometry of Reterobimetalloboranes and Related Species; *Gloeckner, Charles; **Barton, Lawrence; MonsantoCompany, St. Louis MO

WPC Assesment oflnternal Standards for Arsenic in ICPMS; Hinners, Thomas, A.; *Pergantis, Spiros, A. ; Heithmar, Edward,M. ; U.S. Environmental Protection Agency, Las Vegas

WPC Observation of doubly charged mercury cluster ions, n=I-10 by using secondary ion mass spectrometry; *Hiroyuki, Ito;Toshio, Ichihara; Itsuo, Katakuse; Toru, Sakurai; Takekiyo, Matsuo; Dept. of Physics. Fac.ofScience, Osaka Univ.Toyonak~Osaka560,JAPAN

WPC Semi quantitative analysis of complex Polyoxometalate mixtures by means of electrospray ionisation.; *Jennings, KeithR.; Deery, Michael 1.; Howarth, Oliver W.; Department of Chemistry, University of Warwick, Coventry, CV4 7AL. U.K.

WPC Measurements of Nickel-63 and Nickel-59 by AMS for Biomedical Studies; ..Jones, Patrick; *McAninch, Jeffrey;Turteltaub, Ken; Hainsworth, Laura; Marchetti, Alfredo; Straume, Torr; Vogel, John; Lawrence Livermore NationalLaboratory, Livermore, CA

WPC A Transportable Actinide Mass Spectrometer (TAMS) System.; *Kahr, Michael; Olivares, Jose; Abney, Kent; LOll AlamosNational Laboratory, Los Alamos

WPC Elemental Analysis Using an Electrospray Ionization Source Coupled with an FT-ICR Mass Spectrometer; *Milgram,Eric; Goodner, Kevin; Watson, Clifford; Eyler, John; Department of Chemistry, University of Florida, Gainesville, FL

WPC Real-Time Monitoring of Plasma Particles; *Reents, William; Daugherty, John; AT&T Bell LaboratoriesWPC Isotope ratio mass spectrometry using the chemical reaction interface with GC and HPLC introduction; *Teffe~

Yohannes; Kusmierz, Josef; Abramson, Fred; George Washington University, Washington DCWPC Probing Silicon Substitution in Aluminum Phosphate Molecular Sieves by TOF-MS.; *von Heimburg, Shera ; Van

Stipdonk, Mike; Schweikert, Emile; Department of Chemistry, Texas A&M University, College Station, TexasWPC Recent results on the three-aperture gas dynamic vacuum interface for ICP-mass spectrometry; tYing, Ji-Feng;

Douglas, Don; Dept. of Chemistry, Univ. of British Columbia, Vancouver, BC


WPD Analysis on3 Triazine Herbicides by Ion Trap GCIMS/MS; *Abraham, Vincy M.; Lynn, Jr., Bert C.; Mississippi StateUniversity

WPD A Rapid Screening Procedure for the Analysis of Radiolytic Organic Vapor Using SPME/GC-MS; *Alcaraz, Armando;Haas, Jeffery; Whipple, Richard; Grant, Patrick; Andresen, Brian; Lawrence Livermore National Laboratory, Livermore CA94550

WPD Determination ofPAHs in Water Without Extraction Using LCMS; *Canty, John; Bach, Stephan; Streeper, Robert; TheUniversity of Texas at San Antonio

WPD Enhanced Performance of a Micro-Flow Rate Particle Beam Interface in the Analysis of Explosives; *Cappiello, Achille;Famiglini , Giorgio; Berloni, Amaldo; Istituto di Scienze Chimiche, Universita di Urbino, Urbino, Italy

WPD Use of Mass Spectrometry Coupled with a Direct Insertion Probe to Screen PAH Contaminated Soils; Check, Catherine;*Bach, Stephan; The University ofTexas at San Antonio

WPD Molybdenum Ion Trap for Analysis ofOrganochloride Pesticides; *Chen, Ruidan; Palermo, Stephen; Grosshans, Peter;Hitachi Instruments, Inc., 3100 N. First St., San Jose, CA 95134, USA

WPD APCIIMSIMS Method for the Determination of Trace Levels ofSulfonylurea Herbicides in Soil and Water; *Demers,Roger; Mendonca, Mark; Fenwick, John; Matassa, Luca; NOVAMANN International, Toronto,Ontario,CANADA

WPD Identification of Trace Compounds in Soil Using GCIMS in Conjunction with GC/AED Techniques; *Drexler, Dieter;Jordan, Jeannine; Werness, Stephen; McGown, Steven; BASF Corporation, Research Triangle Park

WPD LC-MSIMS Identification and Analysis of a Major Human Urinary Metabolite of Metolachlor; *Driskell, William; Hill,Jr., Robert ; Centers for Disease Control and Prevention, Atlanta, GA

WPD A Cold Trap-Membrane Introduction MS System for the Detection ofVOCs in Water at Low ppt Levels; *Eberlin,Marcos N.; Mendes, Maria Anita; Pimpim, Regina S.; Kotiaho, Tapio; Institute of Chemistry, State University ofCampinasCampinas, SP Brazil

WPD Determination of PCDDIF in Mixed Waste Compost from Small Static Piles; *Eitzer, Brian D.; Mattina, Mary Jane;Berger, William; The Connecticut Agricultural Experiment Station, New Haven, CT

WPD MS analysis of agrochemicals and their metabolites using capillary LCIFAB; *Fujiw~ Hideji; Chott, Robert; MonsantoCompany, St. Louis, Missouri

WPD Rapid Quantitative Determination of 2,4,6-Trinitrotoluene by Ion Mobility Spectrometry; *Garofolo, Fabio; Marziali,Fabio; Pagliuca, Angelo; Migliozzi, Vincenzo; Stama, Angelo; AMI-Aeroporto Pratica di Mare DASRS-RASA 1-00040Pratica di Mare(Rome)ITALY

WPD Analysis of PCBs, PARs, and threat assessment standards by fast GCIHRMS and fast GCITOFMS; *Grainger, James;Green, Vaughn; Barr, John R.; Patterson, Donald G., Jr.; **Holland, Jack; Gardner, Ben; Centers for Disease Control andPrevention

WPD A New Method for Determining Trihalomethane and Cyanogen Chloride Concentrations in Drinking Water; *Griffin,Timothy; Bauer, Scott; Bauer, Janice; MIMS Technology, Inc.

WPD Solid-Phase Microextraction with Fast GCIMS for Benzne, Toluene and Xylenes Analysis; *Grimm, Deborah A.;**Grimm, Casey C.; Tulane University, NewOrleans


WPD Detection ofsemivolatile organic compounds by trap and release membrane inlet mass spectrometry; tLauritsen, FrantsR.; Leth, Mads; Institute of Biochemistry, Odense University

WPD Analysis of pesticides and herbicides in drinking water using large volume injection GC-MS analysis; tLoftus, Neil;Hughes, Jonathan; VG MassLab, Crewe Road, Wythenshawe, Manchester, England. M23 9BE

WPD Real-time Field Analysis of Ground Water Samples using Membrane Introduction Mass Spectrometry-MIMS;tMarkham, Dan; Gilbert, Jeffery; West, Robert; Klecka, Gary; Barcelona, Michael; Major, Jr., C. Lee; The Dow ChemicalCompany, Midland, MI

WPD Analysis ofvolatile organic compounds from solid samples by MIMS; Mansikka, Timo; Ketola, Raimo; Ojala, Marja;"Kotiaho, Tapio; ·Kostiainen, Risto; VTT, Chemical Technology,P.O. Box 1401, FIN-02044 VTT, Finland

WPD Selective Detection of Co planar PCB Congeners by Gas Chromatography Tandem Mass Spectrometry; tMiyares, Paul;Enke, Chris; University of New Mexico

WPD Reduction of Interfering Ion Production in PCB Analysis with NZ ECNCI; tMiyares, Paul; Enke, Chris; University ofNew Mexico

WPD Rapid Determination ofThiourea in Waste Water by FIA-APCI-SRM-MS-MS; tRaffaelli, Andrea; Pucci, Sergio;Lazzaroni, Raffaello; Salvadori, Piero; Centro Studio CNR Macromolecole Stereordinate ed Otticamente Attive

WPD Upgrading the Perkin Elmer QMASS for Higher Sensitivity; Roy, Laura; Graves, Peter; tHamerly, Thomas; Helier, Steve;Detector Technology, Inc., Sturbridge, MA

WPD Pesticide Residue Analysis; A Comparison Between GCIMS and GCIMS/MS; tSchachterle, Steve; Feigel, Carl; VarianChromatography Systems, Walnut Creek

WPD GC-MS Characterisation of Products of Oxidation of SuIfur Heterocycles using Fenton's Reagent; *Sokmen, Munevver;Alien, David W.; Clench, Malcolm R.; Hewson, Allan T.; Sheffield Hallam University, Sheffield, UK

WPD Use of a Direct Insertion Probe with Mass Spectrometry to Pre-Screen Soils for Fuel Contamination; *Stone, Earle;Rico, Catherine; Rodden, Elizabeth; Bach, Stephan; The University ofTexas at San Antonio

WPD Analysis of Thermally Labile Pesticides by GCIMS and GC/MS/MS with Temperature-programmed Injector.; *Vincze,Adam; Yinon, Jehuda; Weizmann Institute of Science, Rehovot, Israel

WPD On-line Postcolumn Photolysis LC-MSIMS Analysis of Isomeric Triazine Pesticides in Food Samples; *Volmer, DietrichA.; Wilkes, Jon G.; National Center for Toxicological Research, Jefferson, AR

WPD Membrane Introduction Mass Spectrometry for Monitoring of Aromatic Compounds in Exhaust Gases; *Walte,Andreas; Matz, Gerhard; Muenchmeyer, Wolf; Gottfried, Kibelka; Technical University Hamburg-Harburg, Hamburg,Germany

WPD Investigating Arsine Generating Reactions by using Deuterium Labeled Reagents and Mass Spectrometry; *Winnik,Witold; Pergantis, Spiros, A.; Heithmar, Edward, M.; **Cullen, William, R.; U.S. Environmental Protection Agency, LasVegas

WPD Real-Time Analysis ofVOCs in Groundwater using In-Situ Sparge Direct Sampling Ion Trap MS *; *Wise, Marcus;Thornpson, Cyril; **Davis, William; Oak Ridge National Laboratory, Oak Ridge, Tennessee

WPD Trace Analysis of Explosives in Water by GCIMS and GC/MSIMS with Temperature-programmed Injector.; *Yinon,Jehuda; Weizmann Institute of Science, Rehovot, Israel

ORGANIC ANALYSIS - IAbstracts are arranged alphabetically by first author

WPE SUPERSONIC MOLECULAR BEAM MASS SPECTROMETRY - THE QUEST FOR ULTIMATE PERFORMANEGC-MS AND FAST GC-MS; *Amirav, Aviv; Dagan, Shai; Tel Aviv University

WPE Trace Analysis in Complex Matrices: Problems and Practical Solutions; *Barshick, Stacy-Ann; Oak Ridge NationalLaboratory, Oak Ridge, TN

WPE LASER DESORPTION FAST GC-MS IN SUPERSONIC MOLECULAR BEAMS; *Dagan, Shai; Shahar, Tzvi; Amirav,Aviv; Tel Aviv University

WPE Fast Multidimensional MS3 Scans in a High-Transmission Pentaquadrupole Mass Spectrometer; *Eberlin, Marcos N.;Kascheres, Concetta; Lago, Claudimir L.; Juliano, Valmir F.; Gozzo, Fabio C.; Institute of Chemistry, State University ofCampinas Campinas, SP Brazil

WPE A New Approach to Organic Mixture Analysis Using Time-of-Flight Mass Spectrometry; *English, Robert; VanStipdonk, Mike; Schweikert, Emile; Department of Chemistry

WPE Analysis of Target Compounds in Highly Complex Matrices using Benchtop GCIMS/MS; *Fannin, Steven; Conoley,Meredith; Edwards, James; Finnigan, Austin TX 78728

WPE Rapid Catalyst and Feedstock Screening by Molecular Beam Mass Spectrometry (MBMS); *French, Richard; Overly,Constance; Broce, Scott; Rejai, Bahman; Meglen, Robert; National Renewable Energy Laboratory, Golden, Colorado

WPE Identification of a Benzalkonium Chloride Contaminant on a Paper Surface by Simultaneous TG-IR-MS; *Lynch,Craig; McGuire, Jeffrey; Hercules Incorporated, Wilmington, DE

WPE Ion-Trap Analysis of Anthraquinone in a Complex Matrix by GCIMSIMS Resonant and Non-Resonant CID; ·Mosi,Andrew; Cullen, William; Eigendorf, Guenter; University of British Columbia, Department of Chemistry

WPE High-energy collision-induced dissociation of homo-N-eJeoxynucleosides; .Rozenski, Jef; Hossain, Nafiza1; Herdewijn,Piet; Rega Institute for Medical Research

WPE Analysis of Commercial Vanilla Extracts Utilizing Multidimensional GCIFTIRIMS; *Sasaki, Tania A.; Wilkins, CharlesL.; University of California, Riverside

PRELIMINARY PROGRAM

ORGANIC ANALYSIS - 11Abstracts are arranged alphabetically by first author

411

WPF Studies of Sulfated Marine Toxins by MS and MSIMS Using a Hybrid Sector/Orthogonal Acceleration TOF; ·Curtis,Jonathan M.; Hu, Tingmo; Wright, Jeffrey L.C.; Institute for Marine Biosciences, NRC, Halifax, Nova Scotia, Canada

WPF Generation of Metalloporphyrins in the source under Fast Atom Bombardment; Domingues, M» Rostrio M.; SantanaMarques, M. Gra a O. ; ·Amado, Francisco M. L.; Ferrer-Correia, A.J.V.; Department of Chemistry, University ofAveiro,3810 Aveiro, Portugal

WPF Comparison of LSIMS and ESI for Measurement of Mass Spectra of Metal-Containing Compounds; ·Geiger, Robert;Busch, Kenneth; Bartlett, Michael; School of Chemistry & Biochemistry, GA Inst. of Technology, Atlanta, GA

WPF Quantitation and confirmation of seven tetracyclines residues in kidney tissues by APcI LCIMSIMS; Kwok, David;·Alleyne, Carl; Chow, Pauline; Young, Larry; "Young, Man Sen; Mori, Brian; Health Protection Branch, Health Canada,Bumaby, B.C., Canada V5G 4P2

WPF Mixed-Metal Cluster Ions in LSIMS Mass Spectra of Acetylacetonates; ·Lemire, Sharon; Geiger, Robert; Downey,Nicolas; Busch, Kenneth; School of Chemistry & Biochemistry, Georgia Inst. Technology, Atlanta, GA

WPF A New Reference Compound for Fast Atom Bombardment High Resolution Mass Spectrometry; ·Longfei, Jiang;Moini, Mehdi; University of Texas at Austin, Austin

WPF Sulfonium Salt Reactions with LSIMS Solvents Induced by Primary Beam Bombardment; ·Melnyk, Michael; Busch,Kenneth; "Dunphy, Richard; Burinsky, David; School of Chemistry & Biochemistry, Georgia Inst. of Tech., Atlanta, GA

WPF Determination of Free Amino Acids and Vitamins by "PLC Particle Beam Mass Spectrometry; ·Mesmer, Mantai;Satzger, R. Duane; Forensic Chemistry Center, USFDA, Cincinnati, OH

WPF Separation and Characterization of Metal Complexed Sulfonated Azo Dyes by Flow FAB MS; ·Sanford, Howard;"Bardole, Heather; Freeman, Harold; North Carolina State University, Department of Chemistry, Raleigh, NC

WPF Soft Ionization MS of Chromanols Produces Radical Cation Molecular Ions; ·Sharp, Thomas; Pfizer Central ResearchWPF Matrix-Enhanced Secondary Ion Mass Spectrometry: A New Method for Molecular Analysis of Surfaces; ·Wu, Kuang

Jen; adorn, Robert W. ; Charles Evans & Associates Redwood City, CA 94063WPF Structural Elucidation of Aporphine-Benzylisoquinoline Alkaloids by APllonspray MS and MSIMS; ·Wu, Wu-Nan;

The R.W. Johnson Pharmaceutical Research InstituteWPF Liquid Ionization Mass Spectrometry for Reaction Study - Formaldehyde Oligomers in a Solution; Kaneko, Takeo;

Yang, Peiming; Saito, Jun; ·Tsuchiya, Masahiko; Yokohama National University, Tokiwadai, Hodogaya-ku, YokohamaJapan

POLYMERS, SURFACTANTS, PETROCHEMICALSAbstracts are arranged alphabetically by first author

WPG Mass discrimination effects in an ion detector exemplified by MALDI mass spectrometry of polymers; • Axelsson, Jan;Scrivener, Elaine; Haddleton, David M.; Derrick, Peter J.; Department of Chemistry, University of Warwick, UK

WPG Measuring Cationization Effects on the MW Distribution ofan Ethoxylated Polymer by ToF-SIMS; ·Conelio-Clark,Paula A.; Hanton, Scott D.; Parees, David M.; Air Products & Chemicals, Inc., Allentown, PA 18195

WPG Nebulised Spray Deposition of Synthetic Polymer Samples for MALDI Analysis; ·Cottrell, John S.; Dwyer, J. L.; Liu, X.;"Willis, James N.; Thermo BioAnalysis Ltd., Hemel Hempstead, UK

WPG A study of cation attachment to polystrene by means of ESI and MALDI.; ·Deery , Michael ; Jennings, Keith ; Buzy,ArrnelIe; Jasieczek, Christina; Haddleton, David; **Jackson, Tony ; Yates, Hilary; Scrivens, Jim; University of Warwick

WPG Polymer Characterization using Radio Frequency Glow Discharge Mass Spectrometry; ·DePalma, Jr., Patrick; Shick, Jr.,Charles R.; Gibeau, Terri E.; Marcus, R. Kenneth; Clemson University

WPG Studies of the Cationization Behavior of Small Oligomers in the MALDII Experiment; Goldschmidt, Robert; Xiong,Yansan; ·Owens, Kevin G.; Hanton, Scott; Department of Chemistry, Drexel University, Philadelphia, PA 19104

WPG Characterization of cyclic polyesters pure or in mixtures using ESI and MALDI Mass Spectrometries; Guittard, Joelle;·Blais, Jean Claude; Bolbach, G rard; Brunot, Alain; Gonnet, Florence; Tabet, Jean Claude; Universit Pierre et Marie Curie Paris

WPG Mass Analysis of a Large, Anionic Spherical Dendritic Macromolecule; ·Haney, Carol; Gorman, Christopher; Parkhurst,Brandon; Chen, Kang-yi; ··Martin, Roy; North Carolina State University, Department of Chemistry, Raleigh, NC

WPG Improved Detection of Poly dispersed Polymers by Combining MALDI-TOF MS with SEC Fractionation; ·Hoberg,Anne-Mette; Haddleton, David M.; Scrivens, Jim H.; Derrick, Peter J.; University of Warwick

WPG Caracterization of Ethylene and Propylene Oxide Copolymers; *Lacey, M.P.; Keough, T.; Pan, Y.; Annstrong, M.P.;Fritz, M.D.; The Procter and Gamble Co.

WPG Desorption Behavior and Distributions of Fluorinated Polymers In MALDI and Electrospray Ionization; ·Latourte,Laurence; • ·Cole, Richard; Blais, Jean Claude; Bolbach, G rard; Brunot, Alain; Gonnet, Florence; Tabet, Jean Claude;Universit Pierre et Marie Curie, CNRS EP 103, Paris

WPG Time-of-Flight Secondary Ion Mass Spectrometry of Substituted Polystyrenes; ·Lee, Yeonhee, K; Han, Seunghee; KoreaInstitute of Science and Technology, Seoul

WPG The Effects of Sample Preparation and Delayed Extraction on the MALDI Analysis of Synthetic Polymers; ·Mowat, IanA.; Donovan, Robert J.; Monaghan, John M.; University of Kent, Canterbury, England, UK

WPG MALDI-TOF MS Study oflndustrial Polymers; ·Rozynov, Boris; Liukkonen, Robert; Sarpong, Martha; Aspen ResearchCorporation, 436 West County Road D, New Brighton, MN 55112

WPG Polymer Analysis by Time-Lag Focusing MALDI TOF MS; ·WhittaI, Randy; Schriemer, Dave; Li, Liang; Department ofChemistry, University of Alberta


WPG MALDI-TOF Analysis of Polyethylene Terephthalate (PET) of Varying Structure; *Yates, Hilary; Scrivens, Jim;Jackson, Tony; **Deery, Michael; ICI Researchand Technology Centre

WPG Sequencing Copolymers using Thermal Desorption-Photoionization Mass Spectrometry; *Zoller, David; Johnston,Murray; University of Delaware, Newark, DE

SEPARATIONIMS TECHNIQUES - INST.RUMENTATIONAbstracts arearranged alphabetically byfirst author

WPH Fast Capillary Electrophoresis Separations With Time-of-Flight Mass Detection; *Banks, J. Fred; Boyle, James; Dresch,Thomas; Gulcicek, Erol; Haren, Patrick; Whitehouse, Craig; Analytica of Branford, Inc.

WPH Towards the development of a practical microspray interface for CE-ESMS applications; *Bateman, Kevin; Thibault,Pierre; White, Robert; Department of Chemistry, Dalhousie University, Halifax, NS, Canada B3H 413

WPH Modular Subatmospheric Pressure Microelectrospray Interface for CE-MS; *Foret, Frantisek; Kirby, Daniel; Karger,Barry L.; Bamett Institute, Northeastern University, Boston

WPH A Novel Electrospray Interface For High Resolution, On-Line ClEF-MS; *Kirby, Daniel P.; Thorne, Jacqueline, M.;Goetzinger, Wolfgang K.; Foret, Frantisek; Vouros, Paul; Karger, Barry L.; Northeastern University, Boston, MA

WPH Comprehensive HPLC-CZE with on-line Electrospray Mass Spectrometry of Peptides; *Lewis, Kenneth; Jorgenson,James; University ofNoth Carolina at Chapel Hill, Chapel Hill, NC

WPH A Comparison of Membrane Interface Designs for Electrokinetic Chromatography I Mass Spectrometry; *Masucci,John A. (1,2); Caldwell, Gary W. (I); Foley, Joe P. (2); The R.W. Johnson Pharmaceutical Research Inst., Spring House,PA 19477

WPH Development of an on-probe capillary separation interface; *Morris, Michael; Lane, Steve; Boughtflower, Robert;Paterson, Clare; Underwood, Tim; VG Organic, Tudor Road, Altrincham, Cheshire WA14 5RZ, UK.

WPH CEIMS and HPLC/MS with an ion trap mass spectrometer; *Stacey, Catherine; Banks, J.Fred; Schubert, Michael; HauserFang, Annettte; Bruker Analytical Systems, Inc., BiIlerica,MA

WPH Analysis of Peptides and Proteins by On-Line CE-Electrospray MS and Off-Line CE-Nanoelectrospray MS; *Sun,Yiping; Bauer, Mark D.; The Procter and Gamble Co.

WPH Capillary Electrophoresis Electrospray Ionization Ion Trap Mass Spectrometry/Mass Spectrometry; *Teng, Siu;Schnute, Bill; Jardine,lan; Schwartz, Jae; Finnigan MAT, San Jose.

WPH The Composite Liquid Junction CEIMS Interface: Refinements, Improvements and Noise Reduction; *Wachs. Timothy;**Sheppard, Robin; Henion, Jack; Cornell University, Ithaca, New York

WPH Capillary Electrophoresis with an On-Line ESI I Ion Trapl Reflectron Time-of -Flight Mass Detector; *Wu, Jingtao;Li, Michael X.; Liu, Lin; Qian, Mark G.; Lubman, David M.; The University of Michigan. Ann Arbor

LIPIDS, HORMONES AND BIOMARKERSAbstracts arearranged alphabetically byfirst author

WPI Identification ofvertebrate type steroid hormones in the shrimp P. japonicus by MSIMS and MSIMS/MS; Cardoso, AnaM.; Barros, Cristina M. F.; *Ferrer-Correia, A. 1.;Cardoso, J. M. ; Cortez, A.; Carvalho, F.; Baldaia, L.; Departamento deQuimica-Universidade de Aveiro-3800 Aveiro-Portugal

WPI ESIMS characterization of phosphatidylinositol phosphates; *Clay, Keith; MacMiIlan, Denise; National Jewish Ctr,Immunology and Respiratory Medicine, Denver, CO

WPI Analysis of Cyclooxygenase and Lipoxygenase Metabolites of Arachidonic Acid by LCIMSIMS; *Duffin, Kevin;Margalit, Alon; Isakson, Peter; Monsanto Corporate Research, Monsanto Company, St. Louis, MO 63198

WPI Nonenzymatic Formation of Biologically Active Eicosanoids During Lipid Peroxidation; *Hall, Lisa, M.; Murphy,Robert, C.; National Jewish Center for Immunology and Respiratory Medicine - Denver

WPI LCIMSIMS Analysis of Peanut Phospholipids; *Haney, Carol; Ruan, Minzi; Sanford, Howard; "Singleton, John; NorthCarolina State University, Department of Chemistry, Raleigh, NC

WPI Studies on Acyl-Co-A with MALDI-TOF PSD and CID MSIMS; *Hsu, Fong-Fu; Gross, Michael L.; Department ofChemistry, Washington University, St. Louis, MO 63130

WPI Determination of Novel Indicators of Human Fecal Pollution in Water by APCI-LC/MS and ESI-LCIMS; *Kryak,David; de la Cruz, Armah; U.S. Environmental Protection Agency, Cincinnati

WPI Characterization of seed oils for potential technical use by HPLC, API mass spectrometry and MSIMS; *Pittenauer,Ernst; Aichinger, Thomas; de Hueber, Karl; Bailer, Josef; Federal Office and Research Center for Agriculture, A-1220 Vienna,Austria

WPI Differentiation of Steroid Isomers by Controlled Fragmentation in APCI-MS; *Sjoberg, Per 1. R.; Markides, Karin E.;Dept. of Analytical Chemistry, Uppsala University

WPI ESI Mass Spectrometric Profiling of Bacterial Phospholipids: Effects of Environmental conditions.; .SweetInan, Gavain;Freestone, Primrose; Trinei, Morella; Toth, Istvan; Norris, Vic; MRC Toxicology Unit, Leicester, UK

WPI Oil-degrading Bacterium Secretes a Novel Anionic Surfactant: Acyloxyacyiated Trehalose Trisaccharide; .WilIiams,Todd D.; Esch, Wynn-Steven; Morton, Martha D.; Buller, Clarence S.; The University of Kansas, Lawrence KS 66045

WPI ESI-MSIMS Analysis ofOzonides of Polyunsaturated Fatty Acids in Phospholipids; Harrison, Kathleen; ·Wheelan, Pat;Murphy, Robert; National Jewish Center for Immunology and Respiratory Medicine

WPI LCIESIIMS and LC/APCIIMS analysis of Triacylglycerols; Zanella, Isabelle; Flament, M.Magdeleine; Girault, Sophie;*Becchi, Michel; CNRS-SCA-Laboratoire de Spectrom trie de Masse-BP 22-69390 Vernaison-France

PRELIMINARY PROGRAM

CLINICAL AND BIOMEDICAL MSAbstracts are arranged alphabetically by first author

413

WPJ Determination of (13C)leucine enrichment in muscle proteins using Isotope Ratio Mass Spectrometry; ·Balagopal, P.;Ford, G.C.; Nair, K.S.; Mayo Clinc

WPJ Characterization of Heterogeneity in MHC Class 11Peptides using MALDI; ·Beeson, Michelle D.; Pohl, Jan; Sundstrom,J. Bruce; Jollow, Kim; Ansari, Aftab A; Microchemical Facility, Winship Cancer Center, Emory University, Atlanta

WPJ Structural Characterization of Human Renal Dialysate Protein by mPC-CE-MS/MS; ·Benson, Linda M.; Tomlinson,Andy J.; Londowski, James M.; Kumar, Rajiv; Naylor, Stephen; Mayo Clinic

WPJ Characterization of Acetaldehyde Modified N-Terminal Peptides of the Hemoglobin Beta Chain.; ·Braun, Karen P.;Pavlovich, James G.; Jones , Danes R.; Peterson , Charles M.; Sansum Medical Research Foundation; Santa Barbara, CA

WPJ Characterization ofGlycated Hemoglobin by Electrospray Ionization Mass Spectrometry.; ·Braun, Karen P.; Pavlovich,James G.; Goldstein, David; Little, Randie; England, Jack; Noffsinger, Jim K.; Peterson, Charles M.; Sansum MedicalResearch Foundation, Santa Barbara, CA

WPJ Quantitative and Qualitative Analysis of Albumin in Human Serum Reference Materials; ·Bunk, David; NationalInstitute of Standards and Technology, Gaithersburg, MD

WPJ Quantification of a New Leukotriene Antagonist (CGP 4S71SA) in Human Plasma Using ESI LC/MS/MS; ·Carlsen,Stephen; Hayes, Michael; Khemani, Lakshmi; Ciba Pharmaceuticals, Summit NJ

WPJ Rapid Analysis of Basic Amino Acids by Tandem Mass Spectrometry; ·Chace, Donald; Hillman,Steven; Duke UniversityMedical Center, MS Facility, Research Triangle Park, NC

WPJ The Conversion of beta-carotene--d8 to retinol-d4 in Humans Using APCI·MS and GCIECNCI-MS; ·Dolnikowski,Gregory; Tang, Guangwen; ••Andrien, Bruce; Tufts University, Boston

WPJ Oecurenee and Levels ofDi- and Trihydroxy Fatty Acids in Generalized Peroxisomal Disorders; ·Evans, James E.;Street, Jacqueline M.; Evans, Barbara A; The E. K. Shriver Center for Mental Retardation, Waltham, MA

WPJ Troponin Analysis by MALDI Mass Spectrometry; ·Fitzgerald, Robert; Harris, Kenneth; Frankel, Wendy; Herold, David;VA Medical Center San Diego and University of Califomia San Diego

WPJ Analysis ofthe Haemophilus inOuenzae proteome using 2-D and tandem mass spectrometry; Hays, Lara G.; ·Link,Andrew J.; Yates, Ill, John R.; Univerity of Washington, Seattle, WA

WPJ The determination of glycated hemoglobin by mass spectrometry; Morris, 'Michael: • Jarvis, Stuart; Green, Brian; Roberts,Norman; VG Organic, Tudor Road, Altrincham, Cheshire WA14 5RZ, UK.

WPJ Automated ESI MS in Clinical Analysis of Variant Hemoglobins.; ·Kim, John; Witkowska, H. Ewa; Lau, Bing-Chuen;··Green, Brian N.; Shackleton, Cedric H. L.; Children's Hospital Oakland Research Institute, Oakland, CA

WPJ Microdialysis and GC/MS ofNAAlNAAG in focal Epileptogenesis; ·Lin, Shen-Nan ; Slopis, John; Willmore, James;Butler, lan; Li, Li; Caprioli, Richard; University of Texas Medical School, Houston, Texas 77030

WPJ Interaction of nitric oxide with biological peptides; ·Mathews, W. Rodney; Laskey, Rachel; Pharmacia & Upjohn,Kalamazoo

WPJ Anatomical Features in Biologic Tissue Determined by Secondary Ion Mass Spectrometry; ·McCandlish, Carl A.;McMahon, John M.; Todd, Peter J.; Oak Ridge National Laboratory, Oak Ridge, TN

WPJ Detection ofspecific disorders in neonates by mass spectrometry; ·Morris, Michael; "Chace, Donald; Hillman, Steven;VG Organic, Tudor Road, Altrincham, Cheshire WA14 5RZ, UK.

WPJ Enhancing Sample Loading in CE-MS Using a Membrane Preconcentration-CE Cartridge (mPC-CE); ·Naylor,Stephen; Benson, Linda M.; Tomlinson, Andy J.; Mayo Clinic, Rochester, MN 55905, USA

WPJ Identification ofFlavopiridol in Clinical Samples using Liquid Chromatography/Mass Spectrometry; ·Phillips,Lawrence R.; Wolfe, Tracy L.; Hill, Kimberly; Stinson, Sherman F.; Laboratory of Pharmaceutical Chemistry, DTP, DCT,National Cancer Institute

WPJ In Vivo Microdialysis and LC/ESI-MS Studies on Kyotorphin-induced Met-enkephalin Release in Brain; ·Prokai,Laszlo; "Roboz, John; Kim, Ho-Seung; Ma, L.; Wang, T.; Center for Drug Discovery, University of Florida, Gainesville

WPJ Diagnosis of Sui fur Amino Acids Metabolic Abnormalities by Automated Electrospray MS/MS; ·Rashed, Mohamed;Ozand, Pinar; AI-Shahwan, Saad; Al-Saban, Essam; Sakati, Nadia; Joshi, Surendra; Jishi, Emtethal; King Faisal SpecialistHospital and Research Centre

WPJ Diagnosis of Metabolic Disorders Using Automated ESI-MS/MS and Computer-Assisted Data Analysis; ·Rashed,Mohamed; Bucknall, Martin; Little, Douglas; Jacob, Minnie; A1-Amoudi,Mohamed; Awad, Amin; Ozand, Pinar; King FaisalSpecialist Hospital and Research Centre

WPJ Mapping of Plasma Proteins using Multi-DimensionaIlHPLC-ESIMS or MALDIIMS; Seta, Kazuo; .Isobe, Toshiaki;Yasukawa, Keiko; "Kanai, Michiko; Ikezawa, Hidenori; Yamaguchi, Mihoko; Okuyama, Tsuneo; Biochemistry, TokyoMetropolitan University

WPJ Analysis of a New Transthyretin Variant Associated with Type I Familial Amyloidotic Polyneuropathy; ·Takahashi,Toshie; "Kasama, Takeshi; Baba, Satoshi; Shimizu, Takao; Dep. Biochem., Fac, Med., University ofTokyo, Tokyo

WPJ A General Strategy for Isolating and Sequencing MHC Class I Peptides; ·Tomlinson, Andy J.; Gallagher, Richard;Derrick, Peter; Butcher, Geoffrey; Powis, Simon; Naylor, Stephen; Mayo Clinic, Rochester, MN 55905, USA

WPJ Thermal in Situ Methylation of Biomolecules for Mass Spectral Analysis; ·Voorhees, Kent; Basile, Franco; Abbas-Hawks,Christy; Hendricker, Alan; Beverly, Michael; Department of Chemistry, Colorado School of Mines, Golden, CO 80401

WPJ Drug screening of amines in biological matrices with on-line CElESIIMS/MS; ·Wheeler, Kevin; Mylchreest, lain;"Lilley, Kim; Wheat, Thomas; Finnigan Corp., subsidiary ofThermoQuest Corp., San Jose, California


TOXICOLOGYAbstractsare arrangedalphabetically byfirst author

WPK Determination ofEDTA in forensic samples by capillary GC-MS and GC-MSIMS; tBallard, Kevin; Orkiszewski, Ralph;"Taylor, Marc; Ragle, Larry; Baylor College of Medicine, Houston, TX

WPK Antibiotic resistance: Novel elimination mechanism characterized by LC-MS and LC-MS-MS; tBateman, Kevin; Yang,Keqian; Thibault, Pierre; White, Robert; Vining, Leo; Dalhousie University, Halifax, NS, Canada

WPK Membrane PC-CE-MS Analysis of3-Phenylamino-I,2-Propanediol (PAP) Metabolites; tBenson, Linda M.; Mayeno,Arthur N.; "Wells, David A.; Tomlinson , Andy J.; Gleich, Gerald J.; Naylor, Stephen; Mayo Clinic, Rochester, MN 55905,USA

WPK Fast Analysis of Anabolic Steroids in.Urine Samples by ESI Tandem Mass Spectrometry; tChang, Yoon-Seok; Chung,Bong-Chul; Jang, Jung-Suk; Yoo, Jong-Shin; Hanyang University, Ansan, Korea

WPK Determination oflncurred Clenbuterol Residues in Bovine Liver Using LC-APCIIMS and MS/MS; tChurchwell, M.I.;Holder, C.L.; Preece, S.W.; Bajic, S.; Doerge, D.R.; National Center for Toxicological Research, Jefferson, AR

WPK Multiresidue Confirmation of Gentian Violet and Leucogentian Violet in Catfish Using LC-APCIIMS; tDoerge, D.R.;Churchwell, M.I.; Rushing, L.G.; Bajic, S.; National Center for Toxicological Research, Jefferson, AR

WPK Quantification of Heterocyclic Amine Carcinogens in Cooked Meats Using LC-APcIIMSIMS; tDoerge, Daniel R.;Holder, C. Lee; "Preece, Steve; National Center for Toxicological Research, Jefferson, AR 72079

WPK Analysis of Heterocyclic Amine Metabolites by uLC-ESIIMSIMS; tEades, Donald; "Malfatti, Michael; Felton, James;Chemistry & Materials Science, LLNL

WPK Identification and Quantification of Spin osad Metabolites in the Fischer 344 Rat using LCIMS.; tGilbert, Jeffrey;Markham, Dan; Domoradzki, Jean; Mendrala, Alan; DowElanco, Indianapolis, IN

WPK Confirmatory analysis of parent spectinomycin residue in bovine tissues by HPLC/APCIIMSIMS; tHornish, Rex; Wiest,John; Pharmacia & Upjohn, Inc., Kalamazoo MI

WPK Studies on Glutathione-Dependent Bioactivation in Rats ofSevonurane Degradate "Compound A"; tJin, Lixia; Davis,Margaret R.; Kharasch, Evan D.; Doss, George A. ; "Baillie, Thomas A.; Dept. of Medicinal Chemistry, University ofWashington, Seattle, WA 98195

WPK Free Radicals in Tamoxifen Metabolism: Study by "On-line" HPLC-Electrospray MS; t Jones, Russell; Lamb, John;White, Ian; Lim, Chang Kee; Smith, Lewis; MRC Toxicology Unit, Leicester UK

WPK Characterization of Fumonisin Mycotoxins by LCIESIIMSn using a Benchtep Quadrupole Ion Trap; t Josephs,Jonathan; Finnigan MAT, San Jose CA

WPK APCI MS and MSIMS for the Structural Analysis of Tocopherols and Their Oxidation Products (I); tMcClure,Thomas, D. ; "Liebler, Daniel, C. ; SW Environmental Health Sciences Center, Univeristy of Arizona, Tucson

WPK Mass Spectrometric Investigations of Quinone/Amino Acid Interactions; tOberth, C.H.; Jones, A.D.; Facility forAdvanced Instrumentation, University of California, Davis

WPK Tandem mass spectrometry as a tool in determining possible causes of disease; tSchurz, Helen R; Hill, Robert H.; Etzel,Ruth; Philen, Rossanne; Posada, Manuel; Neddham, Larry; Centers for Disease Control, Atlanta, Georgia

WPK Applications of ESI-LC-MSIMS to the analysis ofheterocyclic aromatic amines in human urine.; tStillwell, W. G.;Kidd, L. R.; Wishnok, J. S.; "Yu, M. C.; Ross, R. K.; Henderson, B. E.; Skipper, P. L.; Tannenbaum, S. R.; MassachusettsInstitute of Technology, Cambridge, MA 02139

WPK Comparative LCIMSIMS studies ofthe metabolism of 4-ene VPA and its nuoro-analog in rat hepatocytes; tTang, Wei;Jurirna-Romet, Malle; Abbott, Frank; University of British Columbia, Vancouver, BC, Canada

WPK Rapid Identification and Quantitation ofClenbuterol in Bovine Retinal Tissue by LCIESIIMSIMS; tTomlinson, John;Flurer, Rick; Lin, Lorrie; Satzger, R. Duane; Forensic Chemistry Center, U.S. Food and Drug Administration Cincinnati

WPK Quantification of Drugs of Abuse by SPE and GCIMS using Microliter-Amounts of Serum; tWeinmann, Wolfgang;BoOO, Christa; Institute of Legal Medicine, Albertstr. 9, D 79104 Freiburg, Germany

WPK Ultrasensitive Method for the Direct Determination of Vinyl Chloride in Mainstream Cigarette Smoke; tWhite, Earl;Sequeria, Anna; RJ. Reynolds Tobacco Company

WPK Contaminants ofL-tryptophan Associated with the Onset of EMS Characterized by LC-APCI-MS/MS; tWilliamson,Brian L.; Benson, Linda M.; Tomlinson, Andy J.; Mayeno, Arthur N.; Gleich, Gerald J.; Naylor, Stephen; Mayo Clinic,Rochester, MN 55905, USA

LASER DESORPTION - APPLICATIONSAbstractsare arrangedalphabetically byfirst author

WPL Evaluation of Peptide Nucleic Acid Synthesis Products Using MALDI-TOFIMS; tButler, John; Jiang-Baucom, Ping;Huang, Meng; Belgrader, Phillip; Girard, James; National Institute of Standards and Technology, Gaithersburg, MD

WPL DNA-metal interactions studied using MALDIITOF mass spectrometry; Christian, Noah; Houston, Christopher; tReilly,James; Department of Chemistry, Indiana University, Bloomington, Indiana

WPL Mass Spectrometry of Proteins Directly from SDS Gels; tCohen, Steven L.; Chait, Brian T.; The Rockefeller University,New York City, NY

WPL Analysis of Canadian Wheat Varieties by Matrix Assisted Laser Desorption TOF-MS; tDworschak, Ragnar; Ens,Werner; Standing, Ken; ttStevenson, Susan; Hatchet, David; Preston, Ken; University of Manitoba, Winnipeg, Manitoba,R3T 2N2, Canada

WPL Symmetry of Multimeric Proteins Determined by MALDI MS; tFarmer, Terry; Caprioli, Richard; University of TexasMedical School, Houston, Texas 77030


WPL Peptide Profiling with MALDI-TOF MS of Isolated Neurons from Marine Invertebrates; *Garden, Rebecca; Moroz,Leonid; Moroz, Tatiana; Sweedler, Jonathan; Department of Chemistry, University of Illinois, Urbana

WPL Sequencing of nucleic acids by MALDI-MS; *Hahner, Stephanie; Kirpekar, Finn; Nordhoff, Eckhard; Krisiansen, Karsten;Roepstorft', Peter; Hillenkamp, Franz; Institute for Med. Physics and Biophysics, University of Muenster, Germany

WPL MALDI-PSD TOF MS Characterization ofOligosaccharides Prepared by Enzyme-Assisted Synthesis; *Helin, Jari;Costello, Catherine; uRenkonen, Ossi; Boston Univ. School of Medicine, Boston, MA

WPL Ultraviolet MALDI-TOF MS and PSD Structural Determinations of Spore Cortex Muropeptides; *Helin, Jari; Costello,Catherine; uPopham, David; Setlow, Peter; Boston Univ. School of Medicine, Boston, MA

WPL Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns Using MALDIffOF MS; *Holland, Ricky D.;Wllkes, Jon G.; Raffii, Fatemeh; Persons, Cecil C.; Voorhees, Kent, J.; Lay, Jr., Jackson 0.; National Center for ToxicologicalResearch, Jefferson, AR, 72079

WPL Analysis oftheCrude Spider Venom Extracts using MALDI-SectorTandem Mass Spectrometry; *Itagaki, Yasuhuro;Fujita, Tsuyoshi; Naoki, Hideo; Nakajima, Terumi; Suntory Institute for Bioorganic Research

WPL Characterization of PNA by MALDI-TOF Mass Speetrometry: *Jiang-Baucom, Ping; **Butler, John; Wheeler, Nea;Belgrader, Phillip; Girard, James; Department of Chemistry, The American University, Washington, DC 20016

WPL Sequencing of the Responce Regulator Protein SPoOF by MALDI-PSD; *Jones, William; Caldwell, Gary; Masucci, John;The R.W. Johnson Pharmaceutical Research Institute, Spring House, PA. 19477

WPL Analysis of Molybdopterines by MALDI; *Lecchi, Paolo; Pannell, Lewis; G1adishev, Vadim; Laboratory of AnalyticalChemistry, NIDDK, NIH, Bethesda, MD 20892·0805

WPL Fragmentation Mechanisms ofN-Terminal Charge-Localized Peptide Dertvatives; *Uao, Pao Chi; Allison, John; Huang,Z.H.; Gage, Douglas; Roth, Kenneth; Watson, J.T.; Michigan State University, East Lansing

WPL High Resolution Mass Spectrometry ofOligonucleotides with an External Ion Source FTMS; *McIver Jr., Robert T.;uU, Yunzhi; Hunter, Richard L.; Department of Chemistry, University of California, Irvine, CA 92717

WPL Structural Analysis of the HIV-l Protein Nefby Mass Spectrometry; * Mirza, Urooj A.; Lee, Chi-Hon; Kuriyan, John;Chait, Brian T.; The Rockefeller University, 1230 York Av., NewYork N.Y 10021

WPL Proteinase specificities study by MALDI-TOF mass spectrometry; *Moniatte, Marc; Si Tahar, Mustapha; Chignard,Michel; Van Dorsselaer, Alain; Laboratoire de Spectrometrie de masse Bio-Organique, ULP, Strasbourg

WPL MALDI Analysis of Synthetic Oligonucleotides; *Packman, Len C; Dingley, David C; Humphrey, Paul; Department ofBiochemistry, University of Cambridge, Cambridge, CB2 IQW, UK

WPL Mass analysis of growth factors associated with proliferative diabetic retinopathy by MALDI - MS; *Perera, I. K.;Bagga, P.; Verma, D.; Dyer, P. E.; Department of Applied Physics, University of Hull, Hull HU6 7RX, England

WPL Detection of Noncovalent Complexes by MALDI TOF MS; *Pramanik, Birendra; Huang, Eric; Tsarbopoulos, Anthony;Girijavallabhan, V.M.; Ganguly, Ashit; Farmer, Terry; Caprioli, Richard; Schering-Plough Research Institute, Kenilworth, NJ07033-0539

WPL Identification of Bacterial Pathogens by Direct MALDI-MS Analysis of Cellular Proteins.; *Ross, Philip L.;Krishnamurthy, Thaiya; Biopolymer Facility, U. S. Army ERDEC, Aberdeen Proving Ground, MD.

WPL Rapid and Sensitive Analysis of Enzyme Inhibition by a MALDI Mass Tracer Method; *Schrierner, David C.;O'Callaghan, Kelly; Vederas, John; U, Liang; University of Alberta, Edmonton, Alberta, Canada

WPL Stablizing Effects of Complex Formation in MALDI ofOligonucleotides; *Tang, Xiaodong; Vertes, Akos; ChemistryDepartment,The George Washington University,Washington D.C. 20052

WPL Acceleration Voltages Needed for Observation ofMALDI Ions from Surfaces oflnterest to Biochemists; *Vestling,Martha; Johnston, Murray; Larsen, Barbara; University of Delaware, Newark, DE

WPL Searching for the biochemical markers for Alzheimer's disease using immunoprecipitationlMS; *Wang, Rong; TheRockefeller University

WPL Qualification and Validation ora MALDI-TOF Mass Spectrometer for cGMP Compliance; *Wellemans, Joelle; Spaltro,John; Seetharam, Ram; McEntire, John; Adams, Greg ; Microbiological Assocciates, Inc., Rockville, Maryland

WPL The role of mass spectrometry in large-scale DNA sequencing; *Williams, Peter; Chou, Chau-Wen; Dogruel, David;Arizona State University

WPL Comparing MHC Class I Peptide from Normal and Cancerous Murine Mammary Glands.; *Woods, A. S. ; Cotter, R.J.; Sypniewska, R.; Wooley, P.; Pharmacology, Johns Hopkins University Medical School, Baltimore MD

WPL Phosphorylation of Transcriptional Coactivator PC4; *Zhao, Yingming; Qin, Jun; Mirza, Urooj A; Chait, Brian T.; TheRockefeller University, 1230 York Avenue, New York, NY 10021

WPL Quantitative Measurement of Some DMAP-TH Amino Acid Derivatines with MALDI TOF MS; *Zhou, Jie; **Bailey,Jerome; Lee, Terry; Beckman Research Institute of the City of Hope, Duarte, CA 91010

SPRAY IONIZATION • FUNDAMENTALSAbstracts are arranged alphabetically by first author

WPM Short-Time Observation of An Electrospray Curent:Comparison of Positive and Negative Ionisation; *Beaugrand,Claude; Rolando, Christian; Charbonnier, Florence; Simmoneau, Gerard; Ecole Normale Superieure, Departement de Chimie,Paris (France)

WPM Study of Metal-Ligand Interactions with Electrospray FTICR Mass Spectrometry; *Eyler, John; Richardson, David;Burton, Richard; Yang, Yarjing; Watson, Clifford; Department of Chemistry, University of Florida, Gainesville, Florida

WPM Weighing Intact Virus Particles with a Charge Detection Mass Spectrometer; *Fuerstenau, Stephen D.; Benner, W.Henry; Lawrence Berkeley National Laboratory

WPM Optimization of different emitter designs for electrospray ionization applications; *Gale, David C.; **Khosla, Mike;Mylchreest, lain; Sweeney, Matt J.; Josephs, Jonathan L.; Sanders, Mark; Finnigan MAT, San Jose CA

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Quantitative Analysis using MALD/I TOFMS with Electrospray Sample Preparation; Hensel, Russell; Kennedy, Cary;*Owens, Kevin; Hock, Rick; Drexel University Department of ChemistryMultiply-Charged Ions Produced by Sonic Spray Ionization; *Hirabayashi, Atsumu; Hirabayashi, Yukiko; Sakairi,Minoru; Koizumi, Hideaki; Central Research Laboratory, Hitachi, Ltd., Kokubunji, Tokyo 185, JapanInfluence ofskimmer potential on m/z distributions in ESI spectra: Implications for polymers; Hunt, Susan, M.; *Sheil,Margaret M.; Derrick, Peter, J.; "Belov, Michael; University of Woliongong, Wollongong, NSW AustraliaElectrospray Ion Resolvation in a Linear Time-of-Flight Mass Spectrometer; *Lasater, MA; Laude, D.A.; TheUniversity ofTexas at AustinElectrospray mass spectrometry ofsillver-containing adducts of pep tides and proteins.; Li, Hongbo; *Siu, K.W. Michael;Guevrernont, Roger; Inst. Nat. Measurement Stds., National Research Council of Canada, OttawaFundamental Studies Toward the Analysis of Polymerized Monolayers by ESIIMS; *McCarley, Tracy Donovan;McCarley, Robin Lindsey; DuBois, C.J.; Department of Chemistry, Louisiana State University, Baton Rouge, LA 70803Non-linear Model of ESI for Multicomponent Quantitation of Illicit Heroin Samples; Selby, David S. ; *Guilhaus,Michael; Wells[I), Robert; Murby[I), John; School of Chemistry, University of New South Wales, Sydney 2052 AustraliaPerformance of a New Atmospheric Pressure Ion Source for Magnetic Sector Mass Spectrometers; *Shen, Shida;Whitehouse, Craig; Analytica of Branford, Inc.Optimization of APCI LC/MS Conditions for the Analysis of Polycyclic Aromatic Hydrocarbons; *Smith, Richard W.;Marvin, Chris H.; McCarry, Brian E.; Department of Chemistry, McMaster University, Hamilton, ON, L8S 4MI, CANADAFlowing Afterspray. Combining Electrospray Ionization with the Flowing Afterglow Technique.; *Squires, Robert R.;Sunderlin, Lee S.; Chyall, Len J.; Hill, Brian T.; Hu, Jun; Poutsma, John C.; Seburg, Randal A.; Byrd, Dana; PurdueUniversity, Department of Chemistry, West Lafayette, IN 47907Location of Charge Sites in Doubly Protonated Angiotensin 11 Ions Formed by ESI (Part I); *Sullards, Cameron; Adams,Jeanette; Department of Chemistry, Emory University, Atlanta, GA 30322Sensitivity Enhancement of ESI-MS by Operating in the Corona-Assisted Cone-Jet Mode; *Tang, Keqi; Smith, RichardD.; Pacific Northwest National Laboratory, Richland, WAOxidation of Gas-Phase Peptide-Copper Ternary Complexes with Alkali Metal Cations; Vaisar, Tomas; Gatlin, Christine;*Turecek, Frantisek; University of Washington, Seattle, WAElectrospray as an Electrolysis Cell: Electrochemicallonization of Neutrals for Detection by ES-MS; 'Van Berkel, Gary; Zhou, Feimeng; Oak Ridge National LaboratorySolvent and Counterion Effects on Observed Charge States of Diquaternary Ammonium Salts in ESI-MS; 'Wang,Guangdi; Cole, Richard B.; Department of Chemistry, Xavier University, New Orleans, LA 70125Physical Processes of Electrospray Ionization; 'Willoughby, Ross; Sheehan, Edward; Chem-Space AssociatesIon Pairing Effects ofTFA in Electrospray Ionization Mass Spectrometry; *Wolf, Barbara; Russell, David H.; TexasA&M University

COMBINATORIAL LIBRARIESAbstracts arearranged alphabetically byfirst authorOptimization of pp60c-src Substrates by Decoding Peptide Libraries Using LCIMS; *Blackburn, Kevin; Kassel, Daniel;Tian, Gaochao; Knight, B1aine; Glaxo Wellcome, Inc.Pharmacokinetic Characterization of Combinatorial Libraries; *Bodnar, Wanda; Geysen, Mario; Wagner, David;GlaxoWellcome Research InstituteScreening of Combinatorial Libraries using Electrospray Ionization FTICR; 'Fang, Annette; Vouros, Paul; "Stacey,Catherine; Kruppa, Gary; Laukien, Frank; Carell, Thomas; Wintner, Edward; Rebek, Jr., Julius; Northeastern University,Bamett Institute, Boston, MASingle bead mass spectrometry in quality assurance of combinatorial libraries; *Fitch, William L.; Shah, Nikhil; AffymaxResearch InstituteA Question of Cell Permeability: Additional Information Gleaned from Combinatorial Libraries; *Kassel, Daniel B.;Cheng, Soan; Bonner, Ron; Burton , Ron; Knipp, Greg; **Borchart, Ron; CombiChem, Inc. 9050 Camino Santa Fe, SanDiego, CA 92121Library Affinity Selection-Mass Spectrometry: Characterization ofSH2-Ligand Interactions; *Kelly, Michele A.;Liang, Hongbin; Sytwu, Iou-Iou; Wennogle, Lawrence P.; Ciba-Geigy Corp., Pharmaceuticals Div., 5S6 Morris Avenue,Summit, NJ 07901Automatic MUltipledimensional HPLC Coupled with Mass Spectrometry for Qualitative Method Development; *Li,Lily Y.T.; Kyranos, James N.; ArQule Inc. 200 Boston Ave. Suite 3600, Medford, MA 02155Combinatorial Library Automation for Rapid APCI Analysis; *McKay, Richard; Larsen , Barbara; Livingston, Robert;Doughty, James; DuPont Central Research & Development, Wilmington, DEThe Potentials ofESI and MALDI-FTMS in Addressing Structural Diversity of Combinatorial Libraries; *Ross,Charles W.; Ramjit, Harri G.; **Speir, J. Paul; Laukien, Frank; Stacey, Catherine; Kruppa, Gary H.; Merck & Co. Div. MRL,West Point, PAAnalytical Protocol for LCIMS and LCIMS/MS Profiling of Combinatorial Libraries; *Rourick, Robyn A.; Whitney,Jeffrey L.; Klohr, Steven E.; Volk, Kevin J.; Kerns, Edward H.; "Lee, Mike S.; Bristol-Myers Squibb WalIingford, CT06492Qualitative and Quantitative Methods foDecodingEncodedCombinatorial Libraries; *Shah, Nikhil; Fitch, William L.;Affymax Research InstituteMixture Analysis of Biphenyl Diamides Using LC/APCIIMS; *Smith, Ronald G.; Woodard, Scott; Leschinsky, Kindrick;Monsanto Company, St. Louis


WPN Quantification of Iigand/receptor interactions using electrospray LCIMS; ·van Breemen, Richard B.; Huang, Chao-Ran;Nikolic, Dejan; Woodbury, Charles P.; Zhao, Yong-Zhong; Venton, Duane L.; University of Illinois at Chicago, Chicago,lIIinois

WPN Predictive Combinatorial Degradation Profiling; ·Volk, Kevin; Rourick, Robyn; Whitney, Jeffrey; Spears, Tony; Kerns,Edward; Lee, Mike; Bristol-Myers Squibb Wallingford, CT 06492

WPN Automated Mass Spectral Data Analysis for Combinatorial Chemistry; ·Wagner, David; Bodnar, Wanda; Schoenen,Frank; Geysen, Mario; GlaxoWellcome Research Institute

WPN Using Scientific Visualization Software to Analyze Structural Trends in LCIMS Profile Datasets; ·Whitney, Jeffrey L.;··Hail, Mark E.; Rourick, Robyn A.; Volk, Kevin J.; Kerns, Edward H.; Lee, Mike S.; Bristol-Myers Squibb Wallingford, CT06492

WPN Combinatorial library screening by immuno-affinity coupled with ion-spray MS; ·Wieboldt, Ray; Henion, Jack;Analytical Toxicology, Cornell University, Ithaca NY

WPN Characterization of Peptide Combinatorial Libraries By Direct Infusion and HPLC ESI-FrIMS; ·Winger, Brian;Castoro, John; FTIMS, Inc., 6416 Schroeder Rd., Madison WI, 53711-2424

WPN Rapid Lipophilicity Predictive Profiling Using Universal LCIMS Techniques; Beyer, Barbara; ·Starrett, Anne; Thompson,William; DiDonato, Gerald; Lee, Mike; Bristol-Myers Squibb Company, Princeton

WPN Direct Characterization of Solid Phase Resin-Bound Molecules by Mass Spectrometry; Fitzgerald, Micheal; Harris, Ken;Shevlin, Charles; ·Siuzdak, Gary; The Scripps Research Institute, La Jolla, California

WPN Automated High Throughput LCIMS for the Rapid Profiling of Pharmaceutical Compounds; Hail, Mark E.; ·Warrack,Bethanne M.; Arroyo, Anne Starrett; DiDonato, Gerald C.; Lee, Mike S.; Bristol-Myers Squibb Pharmaceutical ResearchInstitute, Princeton, NJ

WPN Automated LC-MS for the Characterisation of Combinatorial Libraries.; Preece, Steve; Batt, Jeremy; ·Rontree, John;"Bott, Peter; VG Organic, Altrincham, WAI4 5RZ, UK.

WPN Screening combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry; van Breemen, Richard B.;·Huang, Chao-Ran; Nikolic, Dejan; Woodbury, Charles P.; Zhao, Yong-Zhong; Venton, Duane L.; University of Illinois atChicago, Chicago, Illinois

PROTEINS AND PEPTIDESAbstracts arearrangedalphabetically byfirst author

WPO Glycoprotein Peptide Mapping with On-line Capillary ElectrophoresislElectrospray Mass Spectrometry; • Apffel, Alex;Chakel, John; Udiavar, Sharmila; Hancock, WilIiam; Swedberg, Sally; "P)Jngor, Erno; M'Timkulu, Thabiso; Hewlett-PackardLaboratories, Palo Alto, CA 94304

WPO Observing Trypsin - Protein Inhibitor Complexes by Electrospray Ionisation Mass Spectrometry.; ·Aplin, Robin;Kraunsoe, James; Lowe, Gordon; ··Green, Brian; Oxford Centre for Molecular Sciences,Oxford University,Oxford, UK. OXI3QY

WPO Mass Spectrometric Characterization of Recombinant Human Factor VIII; Besman, Marc; ·Medzihradszky, Katalin;Maltby, David; Burlingame, Alma; Mass Spectrometry Facility, University of California, San Francisco

WPO Determination of the Extent and Position ofGlycosylation in Mucins; ·Cai, Zongwei; Cerny, Ronald L.; Hollingsworth,Michael A.; Department of Chemistry, University of Nebraska-Lincoln

WPO Structural Characterization of the Glycoprotein alpha-N-Acetylgalactosaminidase; ·Carroll, James; Beavis, Ronald; Zhu,Alex; The Skirball Institue, New York University Medical Center, New York, NY

WPO Noncovalent Quaternary Protein Analysis by MALDI Mass Spectrometry; ·Cohen, Lucinda; Strupat, Kerstin;HilIenkamp, Franz; Institute for Med. Physics and Biophysics, University of Muenster, Germany

WPO Conformation of Gas-Phase Myoglobin Ions; ·Collings, Bruce; Douglas, Don; Dept. of Chemistry, U. of British ColumbiaWPO Detecting Conformations and Conformational Changes by Hydrogen Exchange and Mass Spectrometry; ·Deng,

Yuzhong; Zhang, Zhongqi; Smith, David L.; Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588WPO Observation of a higher order structure for Clostridium perfringens alpha toxins in the gas phase; ·Despeyroux,

Dominique; Lingard, Bryan; Titball, Rick; Watts, Peter; Chemical and Biological Defence Establishment, Porton Down,Salisbury

WPO Detection of Protein Conformations by On-line Rapid Hydrogen Exchange and Protein FragmentationlMS;·Dharmasiri, Kuruppu; Smith, David L. ; University of Nebraska-Lincoln, Lincoln, NE 68588

WPO Correlations Between Protein X-ray Structures and Electrospray Mass Spectra; ·Eckart, Klaus; Verhey, Janko; Spiess,Joachim; Max Planck Institute for Experimental Medicine

WPO Dominant Forces in Gas-Phase Conformations of Protein Ions; ·Guan, Ziqiang; Wood, Troy D.; Kelleher, Neil L.;Aaserud, Dave J.; McLafferty, Fred W.; Cornell University, Ithaca, NY

WPO Local influence of mutations in a cytochrome cS53 probed by isotopic exchanges and ESI-MS; Guy, Philippe; R migy,Herv ; Jaquinod, Michel; Bersch, Beate; Blanchard, Laurence; "Dolla, Alain; Gagnon, Jean; ·Forest, Eric; Institut de BiologieStructurale CEA-CNRS, Grenoble, France

WPO Characterization of Protein-Folding Intermediates by Chemical Trapping and Mass Spectrometry; Happersberger,Peter; Cowgill, Cynthia; Deinzer, Max L.; ·Glocker, Michael 0.; University of Konstanz, POBox 5560M732, 0-78434Konstanz, Germany

WPO Mapping of In Vivo Phosphorylation in Human VDR Protein by Phosphopeptide-selective MS; ·HilIiard, George M.;Huddleston, Michael J.; "Pike, J. Wes; Carr, Steven A; SmithKline Beecham Pharmaceuticals, King ofPrussia, PA

WPO Selective Detection and Sequencing of Phospbopeptides at the Femtomole Level in Protein Digests; ·Huddleston,Michael; Annan, Roland; Carr, Steven; SmithKline Beecham Pharmaceuticals, King ofPrussia, PA 19406


WPO Detection of Phosphorylated and Sulfated Peptides in Total Tryptic Digests by Negative-Ion ESI-MS; ·Jedrzejewski,Paul; Lehmann, Wolf D.; Gennan Cancer Research Center

WPO Proteolytic Digest and Secondary Structure with MALDI; Kriwacki, Richard; ·Wu, Jiangyue; Wright, Peter; Siuzdak,Gary; The Scripps Research Institute, La Jolla, California

WPO Characterization of Gastrointestinal Peptides by Desorption Ionization; ·Larsen, Barbara; McKay, Richard; Gutteridge,Steven; Vestling, Martha; DuPont Central Research & Development

WPO Estimating solution binding constants of Src SIU domains with an API MS/MS system; ·Le Blanc, lC.Yves;"Dalgarno, David; PE-Sciex, 71 Four Valley Drive, Concord (Ontario) L4K 4V8

WPO Competition between protein unfolding and amide hydrogen exchange determined by HR ESIMS.; ·Lund, Eric; Smith,David L.; Department of Chemistry, University of Nebraska, Lincoln, NE, 68588·0304

WPO Protein solution conformations and folding intermediates studied by HID exchange/ESI-MS; ·Maier, Claudia, S.;"Englen, Mark; Kim, Ok-Hee; Schimerlik, Michael, I.; Deinzer, Max, L.; Department of Agricultural Chemistry

WPO Characterization of Glycoprotein Components Using Off-line CEIMS; ·McComb, Mark; Perreault, Helene; University ofManitoba, Chemistry Department, Winnipeg, Manitoba, Canada

WPO Mapping Phosphorylations by Precursor Scans of Unseparated Peptide Mixtures of Gel Isolated Proteins; Neubauer,Gitte; Wilm, Matthias; ·Mann, Matthias; European Molecular Biology Laboratory, Heidelberg

WPO Determination of Protein Reactive Sites by Multiple SORt Experiments in ElectrospraylFTlCR; ·Robinson, J.M.;Bolanos, B.1.; Arkin, R.C.; Campbell, V.L.; Laude, D.A.; The University of Texas at Austin

WPO Identification of Protein Phosphorylation Sites by Capillary IMAC/ LC/ ESI-MS.; ·Russo, Paul; Falchetto, Rocco;Hendrickson, Ronald; Shabanowitz, Jeff; Hunt, Donald; Smith, Gregory; University of Virginia, Charlottesville

WPO Structure determination and functional characterization ofsuccinylated Porin from Rhodobacter caps.; ·Schnaible,Volker; Blueggel, Martin; Glocker, Michael 0.; Przybylski, Michael; "Nestel, Uwe; Diederichs, Kay; Welte, Wolfram;Universitaet Konstanz, Fakultaet fuer Chemie, 78434 Konstanz, FRG

WPO HID exchange studies of peptide fragments comprising protein domains by ESI- MS; ·Shen, Tun-Li; Gage, Douglas A.;Dept. of Biochemistry, Michigan State University, East Lansing, MI 48824

WPO Analysis of Lipoproteins by MALDI and ESI Mass Spectrometry; ·Song, Siqing; Hu, Allison; Macfarlane, Ronald; TexasA&M University

WPO Cu(II}-Peptide Complexes Studied by Mass Spectrometry and Capillary Electrophoresis; ·Song, Siqing; Hu, Allison;Bondarenko, Pavel; Cruzado, Ingrid; Macfarlane, Ronald; Texas A&M University

WPO ESI-MS and MALDI-TOF MS Analysis of Zinc Binding by HIV ne p7 Peptide; ·Sumpter, Terry; Sowder, Raymond, 11;Kane, Bradley; Henderson, Louis; SAIC-Frederick, NCI-FCRDC, Frederick, MD

WPO Protein Glycosylation Analysis Using LCIESIIMSIMS on an Ion Trap Mass Spectrometer; ·Sweeney, Matt; Josephs,Jonathan; Gale, David; Sanders, Mark; Chaudhary, Tanuja; Finnigan MAT, 355 River Oaks Parkway, San Jose CA, 95134

WPO Salt and ligand induced protein conformational changes probed by HID exchange using ESI-MS & LC-MS; ·Tang,Xue-jun; Wang, Fang; Albert Einstein College of Medicine

WPO Mass Spectrometry of Dethiobiotin Synthetase Non-Covalent Complexes; ·Vestling, Martha; Larsen, Barbara; Reiser,Robert; Fogiel, Arthur; Gibson, Katharine; Johnston, Murray; DuPont Central Research & Development

WPO Mass specrometric investigations of noncovalent protein-protein interactions using ESI-sector MS; ·Wang, Jianyao;Busman, Mark; Knapp, Daniel R.; Dept. of Pharmacology, Medical Univ. of South Carolina, Charleston, SC,

WPO Analysis of Peptide Aggregation with Pulsed Field Gradient NMR and ESI MS; ·Williams, Todd D.; Mansfield, Shawn;Jayawickrama, Dimuthu; Larive, Cynthia K.; University of Kansas, Lawrence 66045

WPO O-Iinked Glycosylation Site Identification by Pronase DigestionIMALDI-MS; ·Yang, Vi; Levin, Todd; Austin, Troy;Orlando, Ron; CCRC, University of Georgia, Athens, GA 30602

WPO Analysis of glycoforms of glycoproteins by capillary electrophoresis-electrospray mass spectrometry; ·Yeung, Bernice;Vim, Kalvin; Vath, James; Genetics Institute, Inc., Andover, MA 01810

WPO Higher-Order Structure of Gas-Phase Peptides and Proteins from Gas-Phase HID Exchange Experiments; .Zhang,Zhongqi; Li, Weiqun; Logan, Timothy M.; Guan, Shenheng; Marshall, Alan G.; National High Magnetic Field Lab, FloridaState Univ., Tallahassee, FL

WPO Analysis of phosphopeptides by using liquid chromatography/mass spectrometry; Zhu, Xirong; ·Dass, Chhabil;Department of Chemistry, The University of Memphis, Memphis, TN 38152

THURSDAY POSTERS

ION SOURCE AND MS INSTRUMENTATIONAbstracts are arranged alphabetically by first author

ThPA Quantification of Detection Limits in FTICR-MS; ·Anderson, Gordon A.; Bruce, James E.; Smith, Richard D.; PacificNorthwest National Laboratory, Richland, WA

ThPA Static Secondary Ion Mass Spectrometry Utilizing the Ion Trap; • Appelhans, Anthony; Dahl, David; Delmore, James;Groenewold, Gary; Ingram, Jani; Idaho National Engineering Laboratory, Idaho Falls, ID

ThPA Improved MSIMS Performance on the NERMAG R 3010 Triple Quadrupole Mass Spectrometer; ·Bruins, Andries P.;University Centre for Pharmacy, Groningen, The Netherlands

ThPA Effects of desorption geometries for ions derived from MALDI on the ion trapping in FTICRMS; ·Chan, T-W. Dominic;Wong, Carol K.L.; The Chinese University of Hong Kong, Hong Kong


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Collislonal Foeuslng orIons In the Eleetrospray TOF Mass Spedrometer; *Chemushevich, Igor V.; "Tolmachev, AlexeiV.; Krutchinsky, Andrew N. [1]; Spicer, Victor L. [1]; Ens, Wemer [1]; Standing, Kenneth G~ [1]; Physics Dept., University ofManitoba, Winnipeg MB Canada R3T 2N2Average Ion Kinetic Energy Distributions in a Radio Frequency Glow DIseharge Souree; *Christopher, Steven J.;Marcus, R. Kenneth; Clemson University, Department of Chemistry, Clemson, SC 29634-1905Extended Mass Range Quadrupole Mass Spectrometer; *Collings, Bruce; Douglas, Don; Dept. of Chemistry, U. of BritishColumbia, Vancouver, B.C.Deviees to Guide Ions from Sources to Consumers: A Systematic orIon Guides; *Franzen, Jochen; Bruker-FranzenAnalytik GmbH, Bremen,GermanyDevelopment of a New Benchtop Double-Focusing Magnetic Sector Instrument For LCIMS; Fujimaki, S.; Ishihara, M.;*Kunihiro, F.; Finch, Jeffrey Wo; Cody, Robert Bo; Kammei, Y.; Kubota, E.; JEOL LTD., 1-2, Musashino 3-chome,Akishima, Tokyo 196, JapanCombining FT-ICR with Ion Mobility Spectrometry (IMS); *Giliig, Kent; Bluhm,Brian; Russell, David; Texas A&MUniversity College StationQuantitation Methods in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR-MS); *Goodner,Kevin; Milgram, Eric; Watson, Clifford; Eyler, John; Department of Chemistry, University of Florida, Gainesville, FL 0

Glow Discharge Fourier Transform Ion Cyclotron Resonance Mass Spectrometry(GD-FTICRMS) at High Field;·Goodner, Kevin; Milgram, Eric; Dejsupa, Chadin; Watson, Clifford; Eyler, John; "Barshick, Christopher; Department ofChemisty, University of Florida, Gainesville, FLMicrosecond Pulsed Glow Discharge Mass Spectrometry; ·Hang, Wei; Baker, Cynthia; Smith, Ben; Winefordner, Jim;Harrison, Wiliard; Department of Chemistry, University of Florida, Gainesville, FL 32611TOF-SIMS Using keV Energy C60 Primary Ions; ·Harris, Ronny; Van Stipdonk, Mike; Schweikert, Emile; Department ofChemistry, Texas A&M University, College Station, TexasDesign and performance of a hybrid tandem mass spectrometer with BE/ion trap configuration; Huels, Wilfried;Muenster, Helmut; Pesch, Reinhold; ·Schroeder, Emst; Finnigan MAT GmbH, Barkhausenstr.2, 0-28197 Bremen, Germany.Phosphopeptide Analysis By Microspray Ionization - Hybrid QuadrupolelIon Trap Mass Spectrometry; • Jonscher,Karen R.; Yates, John R., Ill; Dept. of Molecular Biotechnology, University of Washington, Seattle, WAA dual cell mounted in an external source QFTMS, for the study of anion-cation reactions and SID.; Man, Fu Cheong;Perm, Sharron G.; Green, M, Kirk; *Lebrilia, Carlito B.; Department ofChemistry, University of'California, DavisDevelopment of a Portable High Resolution Fourier Transform Ion Cyclotron Mass Spectrometer; ·Milier, Gregory;Koch, Mathias; Hsu, JoP.;Southwest Research InstituteAn Improved Ion Guide Interface for Electrospray LCIMS; ·Mordehai, Alex; Buttrill, Jr., S. E.; Varian Research Center,3075 Hansen Way, Palo Alto, CA 94304·1025Water Cluster Formation in a Novel Low Power Radio Frequency Glow Discharge; *Mowat, lan A; Todd, John FJ;Langford, Marian L; Chemistry Department, University of Kent, Canterbury, Kent, cn 7NH, UKExtended Mass Enhancement for a Commercially Available Quadrupole Mass Spectrometer Series; *Niemann, Scott;··Schiliing, Alexander; CSS Company, Shawnee KansasCan Ion Trap LCIMS/MS Replace Quadrupole LCIMSIMS in Quant. Drug Analysis?; ·Paulson, Jan; uCunniff, Jack;Sehwartz, Jae; Astra Draeo AB, Lund, SwedenOptimizing Quadrupole Performance When Coupled With High Voltage Ion Sources; ·Pedder, Randall; Schaeffer,Richard;.ABB Extrel, 575 Epsilon Drive, Pittsburgh, PA 15238Resolving Isobaric Masses Using a Quadrupole Operated in the Second Mathieu Stability Region; ·Pedder, Randall;Schaeffer, Richard; ABB Extrel, 575 Epsilon Drive, Pittsburgh, PA, 15238Double cylindrical electrode electrostatic ion-guide for API-MS; ·Takada, Yasuaki; Nabeshima, Takayuki; Sakairi,Minoru; Koizumi, Hideaki; Central Research Laboratory, Hitachi Ltd., Tokyo, JapanRF-Only Quadrupoles With Axial Fields; ·Thomson, Bruce; Jolliffe, Chuck; Javahery, Reza; SCIEX, Concord, Canada.TOF-SIMS Using Metal-Oxide Clusters as Primary Projectiles; ·Van Stipdonk, Mike; Harris, Ronny; Ferrell, Ricky;Schweikert, Emile; Department of Chemistry, Texas A&M University, College Station, TexasAn External Source 7 Tesla FT-ICR Mass Spectrometer with Electrostatic Ion Guide; ·White, Forest; Marto, Jarrod;Marshall, Alan; National High Magnetic Field Lab, Florida State Univ., Talllahassee, FL

COMPUTER APPLICATIONSAbstracts are arranged alphabetically by first author

Application of Wavelet Transforms to Electrospray Spectra: Denoising, Smoothing, and Compression; .Barclay, V. J.;Bonner, R. F.; ··Hamilton, I. P.; PE Sciex, TorontoAutomating Mass Spectrometry - Sample Dependent Data Processing; ·Bonner, Ron; Burton, Lyle; Covey, Tom;uMcLean, Matt; PE Sciex Instruments, Toronto, CanadaThe Mass Spectrometry Internet Site - Experiences ofthe First Year; ·Bostwick, David; Shealy, Sarah; Busch, Kenneth;School of Chemistry & Biochemistry, Georgia Inst. ofTechnology, Atlanta GAExtension of the TICFilt Data Treatment Algorithm to SeparationlMS Techniques.; *Carrier, Alain; Zidarov, Dimo;Bertrand, Michel J.; University ofMontreal, MontrealApplication of SIMION 6.0 to Problems in Time-of-flight Mass Spectrometry; *Colby, Steven M.; Manura, John;Scientific Instrument Services, Inc.A Modular System for Tailored Waveform Generation in FTICRlMS Based on VXI and LabVIEW Software;*Dejsupa, Chadin; Dearden, David; Dept. ofChemistry and Biochemistry, Brigham Young University, Provo


ThPB Improved Software Tools for the Analysis of MAL011Tlme-of-FlIght Mass Spectrometry Data; 'Hanton, Scott D.;Owens, Kevin G.; Air Products & Chemicals, Inc., Allentown, PA 18195

ThPB The Use of Modular Excel Macros for Quantltatlon In a GLP Environment; 'Hayes, Michael J.; Carlsen, Stephen F.;Ciba-Geigy Corp., Pharmaceuticals Div., Research Department, Summit NJ Q790

ThPB Using Fuzzy Logic to Accommodating Variance In a Molecular Structure Elucidation System; 'Hemenway, Eric; Enke,Christie; Department of Chemistry, University of New Mexico, Albuquerque, NM 87131

ThPB Algorithms of automated peptide sequencing using partial acid hydrolysis; 'Hffikansson, Per; Klint, Martin; Zubarev,Roman; Sundqvist, Bo U.R.; Uppsala university, Sweden

ThPB A Novel Algorithm to Enhance Signal to Noise Ratios in CE-MS and LC-MS; 'Huang, Baoming M.; Muddiman, DavidC.; Anderson, Gordon A.; Rockwood, Alan L.; Qinyuan, Wu; "Smith, Richard D.; Proctor, Andrew; Pacific NorthwestNational Laboratory

ThPB Effective Searching of Multiple El Data Bases on Hewlett-Packard Data Systems; 'Little, James; "Loh, Stanton;Stauffer, Doug; Eastman Chemical Company, Kingsport, TN

ThPB Automated Determination ofthe Consistency of Mass Spectra and Chemical Structure; 'Mistrik, Robert; Stein, StephenE.; National Institute of Standards and Technology, Gaithersburg MD

ThPB Fragrance creations analysis using semiautomatic spectra (MS, IR) interpretation and olfactoric data; ·Nikiforov, Alex;Jlirovetz, Leopold; Buchbauer, Gerhard; Kornig, Stefan; Inst.Org.Chem.,Univ.Vienna,WlIhringerstr.38,A-I090 Vienna,Austria

ThPB An Internet-Accessible, On-Line Ion Trap Mass Spectrometer for Collaborative Research; ·Price, John M.; Gorshkov,Michael V.; Pacific Northwest National Laboratory, Richland, WA 99352

ThPB ElectroSpray Spectrum Analyser: A new tool to deconvolute multiply charged spectra; ·Proulx, Pascal; Zidarov, Dimo;Bertrand, Michel J.; University of Montreal

ThPB Multi-Dimensional Visualization orlon Trap MS"n Spectra; ·Sander, Peter; Bruker-Franzen Analytik GmbH, Bremen,Germany

ThPB Spectral Simplification of Peptide Sequenclng Data by Massive Inference; Skilling I, John; ·Ferrige, Anthony G.; Green3, Brian; "Zhang, X. Kate; I)MaxEnt Solutions Ltd. Isle., ELY, Camb., UK; 3)VG Organic ALTRIN.Ches. UK

ThPB Quantified ICP-MS Elemental Analysis by Massive Inference and Identification of New Interferences; Skilling, J.;·Ferrige, A.G.; "Gregson, D.; Verbogt, G.; MaxEnt Solutions Ltd. Isleham, ELY, Cambs., UK CB7 5RX

ThPB Mass Spectral Identification Using Substructure Information Generated from Library Searches; ·Sparkman, O. David;O. David Sparkman & Associates

ThPB Data Controlled Modification ofthe Chromatographic Time Frame Using Feedback Flow Modulation; ·Stahl, DouglasC.; Davis, Michael T.; Lee, Terry D; Beckman Research Institute of the City of Hope, Duarte CA 91010

ThPB Development ofa GUI Based Data Reduction Program for FTICR and TOF Mass Spectrometry; ·Watson, Clifford H.;Goodner, Kevin L.; Eyler, John R.; Department of Chemistry, University of Florida, Gainesville, FL 32611-7200

ION-MOLECULE REACTIONSAbstracts are arranged alphabetically by first author

ThPC Ion-Molecule Reactions in FAB - Do They Really Contribute to the Ions Observed?; ·Allison, John; Szekely, Gabriella;Smith, Guy; Noon, Kathleen; Michigan State University, East Lansing

ThPC Investigations of ion formation, fragmentation and collisions using DC and pulsed ion extraction; Arnold, Randy;Christian, Noah; ·Reilly, James; Department of Chemistry, Indiana University, Bloomington, Indiana

ThPC SIFT/CID Studies ofthe Ligation ofFe+ and (c-CSH5)Fe+ with Hydrocarbons.; Baranov, Vladimir; Becker, Hansjuergen;Schwarz, Helmut; ·Bohme, Diethard, K.; York University,North York, Ontario, Canada

ThPC The Role of Radiative Relaxation in the Fe+ Catalyzed Polymerization ofChlorobenzene; ·Bjamason, Asgeir; Ridge,Douglas; University of Delaware, Newark, DE

ThPC A Structural Study of the Metallo-Carbohedrene Nb8C12+; ·Byun, Yong; Lee, Samuel; Kan, Steve; Freiser, Ben; PurdueUniversity, West Lafayette, Indiana

ThPC Comparison of different FeCX+ complexes through their ion-molecule reactivity; ·Capron, Laure; Mestdagh, Helene;Rolando, Christian; Ecole Normale Superieure, Paris (France)

ThPC Gas-phase reactivity of small and large Fe(H20)n+ cluster ions; ·Capron, Laure; Delcominette, Eric; Mestdagh, Helene;Rolando, Christian; Sootier, Michel; Pradel, Pierre; Visticot, Jean-Paul; Mestdagh, Jean-Michel; Ecole Normale Superieure,Departement de Chimie, Paris (France)

ThPC Gas Phase Coordination Chemistry: How is it Relevant to Condensed Phase Coordination Chemistry?; ·Fisher, Keith;WiIliams, Brett; Dance, Ian; WiIlett, Gary; School of Chemistry, University ofNew South Wales

ThPC Organolanthanide complexes from reactions oflaser-ablated lanthanide ions with cyclic hydrocarbons; ·Gibson, JohnK.; Oak Ridge National Laboratory

ThPC Chiral Selectivity in Gas-Phase Proton Transfer: Reactions of Amines with Cytochrome c; ·Green, M. Kirk; Camara,Elvira J. 0.; Penn, Sharron G.; Lebrilla, Cartito B.; University of California, Davis

ThPC Solvation Effects on the Stability and Reactivity of Multiply Charged Gas-Phase Ions; ·Gross, Deborah; Zhao, Yuexing;WiIliams, Evan; University of California, Berkeley

ThPC Radiative association rates and bond strengths of metal ion complexes; ·Ho, Yen-Peng; Dunbar, Robert C.; Departmentof Chemistry Case Western Reserve University

ThPC Gas-Phase Reactions of Fullerene Ions with Ozone; ·Holliman, Christopher; McElvany, Stephen; Naval ResearchLaboratory; Washington, D.C. 20375

ThPC Gas Phase Solvation Effect on Proton Transfer: Case Study ofAmino Acid Solvated by Ammonia; Huang, Yong;·Russell, David H.; Texas A&M University, College Station


ThPC Reactions of Nicotine Analogs: Functional Group Selectivity of Electrophiles; *Isbell, John; Brodbelt, Jennifer; Seeman,Jeffrey; University Texas at Austin, Austin .

ThPC Generation and Catalytic Activity of (Ptn)+ Ions, n =1-4; *Jackson, George S.; HammiJI, Cindy; Clark, Ronald J.;Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

ThPC Gas-Phase Ion-Molecule Reactions ofC60CoFe+; *Kan, Steven; Byun, YongGwan; Freiser, Ben; Purdue University, WestLafayette

ThPC Coupling Reactions of Gas Phase Fe(benzyne)+ and Fe(naphthyne)+ by FTMS; *Kan, Steven; Freiser, Ben; PurdueUniversity, West Lafayette

ThPC The Use of Trimethyl Borate as a Cl Reagent for the Analysis of Biologically Active Molecules; *Kempen, Esther;Brodbelt, Jennifer; University of Texas at Austin, Austin TX.

ThPC Ion-Molecule Reactions with Hydrogen Cyanide in a Ion Trap Mass Spectrometer; *Koenig, Stefan; Kofel, Peter;Schlunegger, Urs P.; Institute of Organic Chemistry, University of Bern, CH-3OJ2 Bern

ThPC Determination of the Gas-Phase Acidities of Uracil ,5-Fluorouracil, and Thymine by FT-ICR MS; *Li, Weiqun;Santos, Ivan; Marshall, Alan G.; National High Magnetic Field Lab, Florida State Univ., Tallahassee, FL

ThPC Transition Metal Transfer Between Crown Ethers; *Liang, Yongjiang; Dejsupa, Chadin; Pope, R. Marshall; Dearden,David; Dept. of Chemistry and Biochemistry, Brigham Young University, Provo

ThPC Radiative association reactions of chromium cation with benzene and benzene derivatives; *Lin, Chuan-Yuan; Dunbar,Robert C.; Department of Chemistry, Case Western Reserve University

ThPC Comparison of Halocarbon - PAH Ion Molecule Reactions in an Ion-Trap and a Quadrupole Source; Mosi, Andrew;Cullen, WiJliam; *Eigendorf, Guenter; University of British Columbia, Department of Chemistry

ThPC Ion-molecule complex lability in the gas phase for alkali metal ion-crown ether systems; *Nicoll, Jeremy; Dearden,David; Dejsupa, Chadin; Dept. of Chemistry and Biochemistry, Brigham Young University, Provo

ThPC FT ICR study of chirality effect in the formation of protonated and ammoniumated dimers and trimers; *Nikolaeva,Marina; Nikolaev, Eugene; **Ridge, Douglas; Futrell, Jean; The Institute of Energy problems of Chemical Physics, Moscow,Russia

ThPC Clustering Reactions of Metal Ions in Excited Electronic States; *Peterman, Scott; Russell, David; Texas A&M UniversityCollege Station

ThPC Regioselective protonation and SN from epimeric 1,4-cyclohexanediol derivatives; Rathahao, Estelle; Perlat, MarieClaude; ·Fournier, Francoise; Tabet, Jean-Claude; University Pierre and Marie CURIE (PARIS)

ThPC Proton Transfer Reactions of Doubly Protonated Diamines Containing Polarizable Groups; *Rodriguez-Cruz, Sandra E.;Williams, Evan R.; University ofCalifornia, Berkeley

ThPC Temperature and Size Dependence of Radiative Association Rates.; *Ryzhov, Victor; Dunbar, Robert C.; Klippenstein,Stephen J.; Department of Chemistry, Case Western Reserve University

ThPC Electrospray of Alkaline Earth Halides and Ligand Exchange Reactions of Their Crown Ether Complexes; *Shen,Nanzhu; Pope, R. Marshall; Dearden, David; Dept. of Chemistry and Biochemistry, Brigham Young Univeristy, Provo

ThPC Reactions of Hydantoin and Succinimide Anticonvulsants with Dimethyl Ether Ions in a QIT; *Shen, Jim; Brodbelt,Jennifer; University of Texas at Austin

ThPC Determination ofthe stereochemistry of Nilcarbohydrate complexes using FAD- and ESI-tandem MS; *Smith, Glenn;Leary, Julie A.; College of Chemistry, University of California, Berkeley, CA 94720·1460

ThPC Gas-phase Reactions of Biopolymers in a MALDI QUlSTOR TOF-MS; *Stoeckli, Markus; Kofel, Peter; Schlunegger, UrsP.; Institute of Organic Chemistry, University of Berne, Switzerland

ThPC ELECTROSPRAY ION TRAP MS(n) MAPPING OF SURFACTANTS; *Strife, Robert J.; Ketcha , Marcia M.; Procter &Gamble Miami Valley Laboratories, Cincinnati, OH

ThPC ELECTROSPRAY ION TRAP MS(n) OF SURFACTANTS - VERY UNSATURATED IONS FROM SATURATEDAMIDES; *Strife, Robert J.; Ketcha, Marcia M.; Procter & Gamble Miami Valley Laboratory, Cincinnati, OH

ThPC Electronic Effects in the Gas Phase Reactions of Ta+, Pt+ and Au+ with Small Alkenes; *Taylor, William; Campbell,Allyson; Department of Chemistry, University ofCentraI Arkansas, Conway, AR 72035

ThPC Ligand Effects in C-H and C-C Bond Activation by Gas-Phase Transition Metal-Ligand Complexes; *Tjelta, Brenda L.;Armentrout, P. B.; Department of Chemistry, University of Utah, Salt Lake City, UT

ThPC IInfrared Photodissociation of Gas Phase Cluster Ions in a FTICR Spectrometer; *Tonner, Scott; McMahon, Terry;University of Waterloo

ThPC Laser Ablation Mass Spectrometry of Tin Sulfide; *Willett, Gary; Jackson, Phillip; Dance, Ian; Fisher, Keith; Gadd, Gerry;School of Chemistry, The University of New South Wales, Sydney, NSW 2052.

ION ACTIVATION AND DISSOCIATIONAbstracts arearranged alphabetically byftrst author

ThPD Dissociation of methyl, ethyl and iso-propyl phenyl esters.; *Aubry, Christiane; Holmes, John L.; Chemistry Department,University of Ottawa, Ottawa, Ontario, Canada.

ThPD Thermally Induced Desolvation and Dissociation of Ions in a New ESI TOF Mass Spectrometer; *Bondarenko, Pavel;Song, Siqing; Macfarlane, Ronald; Department of Chemistry, Texas A&M University, College Station, TX 77843

ThPD Role of isomeric structures in mechanism and energetics of fragmentation, the case of benzene ion.; *Chawla, Rahul;Shukla, Ani!; Futrell, Jean; University of Delaware, Newark, Delaware

ThPD HydrogenlDeuterium Exchange Reveal Hydrogen Transfer During Fragmentation of Peptide b210ns; *Eckart, Klaus;Spiess, Joachim; Max Planck Institute for Experimental Medicine, Goettingen

ThPD Fragmentation of a Per(onio) Substituted Benzene; *Fales, Henry M.; Zhang, X. Kate; National Heart, Lung, and BloodInstitute, NIH , Bethesda, MD 20892


ThPD Charge transfer in collisions between gaseous protein ions and inert gases.; Giannakopulos, Annastassios E.; • Andersen,UlIa N.; Christie, John R.; Reynolds, David J.; Derrick, Peter J.; University of Warwick

ThPD On the Loss of 17 u from Peptide Ions; ·Giblin, Daryl; Gross, Michael; Department of Chemistry, Washington University,St. Louis, MO

ThPD Dissociation mechanism of hydrocarbon molecules and radicals by charge inversion mass spectrometry.; ·Hayakawa,Shigeo; Endoh, Hirohisa; ..Arakawa, Kazoo; Morishita, Norio; College ofIntegrated Arts & Sciences, Osaka PrefectureUniversity, Sakai

ThPD Energy-resolved collision-induced dissociation of deprotonated mononucleotides; Ho, Yeunghaw; ·Kebarle, Paul;Department of Chemistry, University of Alberta, Edmonton, Canada T6G 2G2

ThPD To distinguish between PSD- and CID-fragment ions of peptides in a MALDI-RETOF-MS; ·KOster, Claus; Holle,Annin; Bruker-Franzen Analytik GmbH, Bremen, Germany

ThPD Ortho-Cyclization of Substituted Aryl~yclopropanesin Gas and Liquid Phase; ·Lebedev, Albert; Mochalov, Sergei;··Tretyakova, Natalia; Hass, J. Ronald; Moscow State University, Moscow, Russia

ThPD Reaction dynamics ofdifluoroethylene ions; ·Leyh, Bemard; Locht, Robert; Franck, Beno"t; Department of Chemistry,Li ge University, B.4000 SART-TILMAN

ThPD MSIMS ofN and C-terminal Derivatized Peptides with a Quadrupole Ion Trap; ·Lin, Tong; Glish, Gary L.; Universityof North Carolina at Chapel Hill

ThPD Target Capture of Noble Gas Atoms by Fullerene Radical Cations.; ·Mosely, Jackie. A; Gallagher, Richard. T; Derrick,Peter. J; University of Warwick

ThPD Relative Reaction Cross-Sections and Dynamics for Collisional Di ssociation of the Fullerene Ions; ·Nishimura,Toshihide; Pharmacia and Upjohn Inc.

ThPD Low-energy CID of Molecule Ions Generated from Ricinoleic and Ricinelaidic Acid; Nizigiyimana, Liberata; Van denHeuvel, Hilde; ·Claeys, Magda; University of Antwerp (UIA)

ThPD Internal Energy Effects on Low and High Energy Collision-induced Dissociation; ·Ospina, Maria; Yost, Richard A.;Powell, David H.; University of Florida, Gainesville, FL.

ThPD Collision Induced Dissociation of Doron Oxide Ion Clusters Studied by the Guided Ion Beam Technique.; ·Peiris,Dilrukshi; Lapicki, Adam; Anderson, Scott L.; University of Utah, Department of Chemistry

ThPD The relationship between structure and relative CID thresholds for oligosaccharides, in MALDI FTMS; ·Penn, SharronG.; Cancilla, Mark T.; Hedrick, Jerry L.; Lebrilla, Carlito B.; Department of Chemistry, University of California, Davis, CA95616.

ThPD Experimental Evidence that Neutral Glycine has the Structure.NH2-CH2-COOH in the Gas Phase; ·Polce, Michael J.;Wesdemiotis, Chrys; Department of Chemistry, The University ofAkron, Akron OH 44325-3601 USA

ThPD fragmentation induced by ion-atom reactions; ·Rolando, Christian; Leymarie, Nancy; Poisson, Lionel; Mestdagh, Helene;Sablier, Michel; Ecole Normale Superieure, Paris (France)

ThPD Fragmentation Pathways of Cationized Permethylated Maltoheptaose under Diverse Conditions; Reinhold, Bruce;Helin, Jari; Ngoka, Lambert; Ye, Song; Reinhold, Vemon; ·Costello, Catherine; "Marshall, Alan; Boston Univ. Schoool ofMedicine, Boston, MA

ThPD Structural Characterization ofPorphyrins by high-energy FAD CID-MSIMS; ·Shibue, Toshimichi; Kambe, Hisashi;Nishide, Hiroyuki; Akashi, Satoko; Dohmae, Naoshi; Takio, Koji; "Ohashi, Yoko; School of Science and Engineering,Waseda University, Tokyo

ThPD Crossed-beam study of collisional excitation of CS2+ and C02+ at intermediate energies; ·Tosh, Ronald E.; Shukla, AnilK.; Futrell, Jean H.; Chemistry and Biochemistry, University of Delaware, Newark DE 19716

ThPD Stereochemical effects in fragmentation of pentapeptides with one N-alkylated amino acid; ·Vaisar, Tomas; Urban, Jan;Molecumetics Ltd., Bellevue, WA

ThPD Mixed Site vs. Charge Site Remote Fragmentations of Long-chain Quaternary Ammonium Ions.; ·Whalen, Kevin;Grossert, J. Stuart; "Boyd, Robert K.; Dalhousie University, Halifax, Canada

ThPD MSIMS ofPCD Isomers Using a Sector/Orthogonal-TOF Hybrid Instrument; ·Whalen, Kevin; Grossert, J. Stuart;··Boyd, Robert K.; Chan, Kenneth; Curtis, Jonathan M.; LeBlanc, M. Denise; Dalhousie University, Halifax, Canada

ThPD Trace Detection ofElectrophores by EC-FTMS; ·Zhang, Tianlan; Van Orden, Steven; Laukien, Frank; Huang, Yulin; Giese,Roger; North Eastern University, Boston, MA

ThPD Collision-induced dissociation ofCS2++ with Ar at high collision energy; ·Zhou, Xuedong; Shukla, Anil; Futrell, Jean;University of Delaware

POLYMERS, SURFACTANTS, PETROCHEMICALSAbstracts are arranged alphabetically by first author

ThPE Chemical Ionization of Diomarkers in an Ion Trap Mass Spectrometer; ·Cameron, A.S.; Roussis, S.G.; Imperial Oil,Samia Research Centre, Samia, Ontario, Canada, N7T 7Ml

ThPE Characterization of Melamine Resins Using Liquid ChromatographylMass Spectrometry; Chang, Ted; ·Piquette,Michael; Cytec Industries, Stamford, CT USA

ThPE Analysis ofthe emanations from heated polyurethane foam using MAD-MS.; ·Cyr, Marc; Faubert, Denis; Mousselmal,Moussa; Bertrand, Michel.J; University of Montreal, Montreal

ThPE Comparison of MAD and El for petroleum mass spectrometry; ·Faubert, Denis; Mousselmal, Moussa; Roussis, StilianosG.; Bertrand, Michel J.; University ofMontreal, Montreal

ThPE Computerized surfactant analysis by MS-FAD.; Hazos, Marta; Piemonti, Carmen; ·Bruzual, Jenny; Mendez, Aaron;INTEVEP, SA

PRELIMINARY PROGRAM

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APCI LCIMS of Metalloporphyrins; ·Fukuda, Elaine K.; Wang, Yanping; "Hsu, Chang Samuel; CAFT MassSpectrometry Facility, Rutgers University, New Brunswick, NJUnraveling the Kinetics of Petroleum Destruction by Usingl,2-13C2 lsotoplcaUy Labeled Dopanu; ·Gregg, Hugh;Bumham, Alan; Lawrence Livermore National LaboratoryCharacterization of Processed Heavy Crude Oils: Residsand Asphaltenes; ·Hunt, Ierry; Winans, Randall; ··Miller,Jeffrey; Argonne National Laboratory, Chemistry Division, ArgonneUtilising Precursor Ion Scanning and MS/MSIMS Techniques for the Analysis of PolymerAdditives; • Jackson, Tony;Scrivens, Jim; Yates, Hilary; Jennings, Richard; ••Jennlngs, Keith; ICI Research and Technology CentreFfIMS Analysis of Common Anionic and Nonionic Surfactanu; ·Ludicky, Robert; Morton Intemational, 1275 LakeAvenue, Woodstock, IL 60098The Influence of Pump Oil Purity on Roughing Pumps; ·Overton, Santford V.; Manura, John J.; Scientific InstrumentServices, Inc., Ringoes, New Jersey 08551OLIGOM: A computerized mass spectrum analysis applicable to oligomeric mixtures.; ·Piemonti, Carmen; Hazes,Marta; INTEVEP, SADifferentiation of Isobaric Monomers Contained in Complex Polymers; ·Ross, lll, Charles W.; Simonsick, It., William J.;DuPont Marshall Laboratory, Philadelphia, PA 19146

SEPARATIONSIMS TECHNIQUES - APPLICATIONSAbstracts arearrangedalphabetically byfirst authorThe Analysis of Drugs and their Metabolites in Urine using CE-ES-MS; ·Ashcroft, Alison E.; Giles, Roger; Major, HilaryI.; McKenna, Therese; "Wilson, Ian D.; VG ORGANIC, Tudor Road, Altrincham, Cheshire, WAI5 5RZ, UK.Pharmaceutical Applications ofCEIMS for Structural Determination of Peptide Mixtures; ·Chan, Stephen; Armstrong,Barbara; Burinsky, David; Oyler, Alan; R.W. Johnson Pharmaceutical Research Institute, RaritanAn Investigation of Cerebrospinal Fluid Proteins Using a New Microspray cIEF-MSIMS System; ·Clarke, Nigel I.;Johnson, Kenneth L.; Tomlinson, Andy I.; Kirby, Daniel P.; Karger, Barry L.; Naylor, Stephen; Mayo Clinic, Rochester, MN55905, USAComparison of Capillary ElectrochromatographylMS, CZE/MS and ubore LCIMS for Agrochemicals Analysis;·Cooper, Paul; Jessop, Mike; Moffatt, Frank; Crosland, Susan; Zeneca Agrochemicals, Bracknell, UKCapillary Electrophoresis I Mass Spectrometry for the Routine Analysis of Organic Acids.; Cotton, Nick; Rumbelow,Steve; ·Scrivens, Jirn; Taylor, MIke; Yates, Hilary; ICI Research and Technology Centre, Middlesbrough, UKUsing phosphate and citrate buffers in online CEIMS: Trials and tribulations; .·Craze, Andy; ·Bruins, Andries P;University Centre for Pharmacy, Groningen, NederlandDirect Analysis of Cellular Components by CE-ESI-FfICR; ·Hofstadler, Steven A; Severs, Joanne C.; Swanek, Frank D.;Ewing, Andrew G.; Smith, Richard D.; Pacific Northwest National Laboratory, Richland, WAAnalysis of Fumonisin BI in Rodent Feed by Capillary Electrophoresis and Confirmation by ESMS; ·Holcomb,Manuel; Thompson, Jr., Harold; FDA, National Center for Toxicological Research, Jefferson, ARCapillary electrophoresis-mass spectrometry of drugs and metabolites in biological matrices; ·Lilley, Kirn A.; Wheat,Thomas E.; ATI Separations -Part of Thermo Instruments; Boston, MAPractical Considerations: Analysis of DruglXenobiotic Metabolites, Peptides, and Proteins by CE-MS; ·Naylor,Stephen; Benson, Linda M.; Tomlinson, Andy I.; Mayo Clinic, Rochester, MN 55905, USAAnalysis of Anions by CEMS on a Hybrid Tandem Mass Spectrometer; ·Nitowski, Albert I.; Moore, Colin; Bairley,David W.; "AI-Mudamgha, Areej A; Robinson, Steve; Uniroyal Chemical Company, Inc.Charge Concentration for High Sensitivity ITMS Detection of Biopolymers; ·Ramsey, R.S.; Goeringer, D.E.; McLuckey,S.A.; Oak Ridge National Laboratory, Oak Ridge TN 37831-6365Analysis of Dyes by CEIMS; ·Tetler, Lee; ··Cooper, Paul; Sheffield Hallam University, SheffieldAttomole Sensitivity Analysis of Recombinant Proteins by Picospray-CEIFfICR-MS; ·Valaskovic, Gary A.; Kelleher,Neil, L.; Mcl.afferty, Fred W.; Comell University, Ithaca, NYMass spectrometry ofsmall molecules separated by capillary electrophoresis; ·Wheat, Thomas E.; Lilley, Kim A.; ATISeparations -Part of Thermo Instruments; Boston, MA

LIPIDS, HORMONES AND BIOMARKERSAbstracts arearranged alphabetically byfirst authorThe Determination of Catechol Estrogen Levels in Breast Tissue; ·Cai, Zongwei; Cemy, Ronald L.; Rogan, Eleanor G.;Cavalieri, Ercole L.; Department of Chemistry, University ofNebraska-LincolnHPLC-MSIMS method for detection of benzene metabolites S-phenylmercapturic acid and t,t-muconic acid; ·Coleman,Stuart; O'Connor, Ray; Hu, Pei-Feng; Melikian, Assieh; American Health Foundation, 1 Dana Road, Valhalla, NY 10595Quantification of ceramides and dihydroceramides using FMOC derivatization and HPLC/APCI-MS; ·Couch, LethaH.; Churchwell, Mona I.; Tolleson, William H.; Howard, Paul C.; Doerge, Daniel R.; National Center for ToxicologicalResearch, FDA, Jefferson, AR 72079Classification of Bacteria by Gas ChromatographylMass Spectrometry and Patterv Recognition Analysis; ·Gharaibeh,Ahmad A; Voorhees, Kent I.; Department of Chemistry, Colorado School of Mines, Golden, CO 80401Analysis of dolichols and polyprenols and their derivatives by El, FAB and ES tandem MS; ·Griffiths, William;Lundsjo, Anders; Hjertrnan, Magnus; Wejde, Johan; Larsson, Olle; SjOvall, Jan; Karolinska Institute, StockholmTandem mass spectrometry of cysteinylleukotrienes; ·Griffiths, William; Yang, Yang; Lindgren, Ian Ake; SjOvall,Jan;Karolinska Institute, Stockholm

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Quantitation of Novel C24:x Polyunsaturated Fatty Acids by Negative Chemical Ionization GCIMS; *Hachey, David L.;Sauerwald, Thorsten U.; Nannegari, Vijay; Jensen, Craig L.; Heird, William C; Baylor College of Medicine, Houston, TX77030Identification of PAF and acyl-PAF species in human blister fluid in vivo; *Johnson, Christopher A.; Travers, Jeffrey B.;Clay, Keith L.; Zekman, Tami; Morelli, Joseph G.; Murphy, Robert C.; National Jewish Center for Immunology andRespiratory MedicineIdentification of Complex Mixtures ofCeramides and Cerebrosides by ESI-MS and ESI-MSIMS; *Kerwin, James;**Gu, Ming; Watts, Julian; Aebersold, Ruedi; Botany 351330, University of Washington, Seattle, WA 98195 USAEffect of ethanol on incorporation of polyunsaturated fatty acids in C-6 glioma cells; Kim, Hee-Yong; Ma, Yee-Chung;Section of Mass Spectrometry, LMBB, NlAAA, NIHCF-LSI Mass Spectrometric Detection lIfPhospholipids in DMSO-Differentiated U937 Cells; -u, Chun; Wong,Elizabeth; Yergey, James; Merck Frosst Canada Inc., MontrealSearching for Novel Bile Acids in Marsupials with Mass Spectrometry; Pyrek, Jan St.; *Song, Jiangao; University ofKentucky Mass Spectrometry Facility, Lexington, KY andMetabolism of Saponins by Mass Spectrometry: Transformations of Nuatigenin, Sapogenin from Oats; Pyrek, Jan St.;Aggarval, Suressht K.; Goodman, Jack P.; Barboza, Perry; Yang, Pei-Ying; *Song , Jiangao; Jackson, James A.; University ofKentucky Mass Spectrometry Facility, Lexington, KY andMALDI-FT-MS and MS-MS offully Blocked Glucuronides and Glucosides of Steroids and Bile Acids; *Pyrek, Jan St.;Song, Jiangao; Hadd, Harry E.; University of Kentucky Mass Spectrometry Facility, Lexington, KYCharacterization of omega-acyloxy-ceramides by FAD-MS/MS on a four-sector tandem mass spectrometer; *Rubino,Federico Maria; "Chen, Su; C.E.M.O.C. Lab.for Occupational Toxicology and Allergology, Milano (Italy)LClIonSpray/MS/MS Analysis of Bile Acids; *Sakuma, Takeo; Sanchez, Gabriel; Burton, Lyle; Shushan, Bori; PE Sciex

DRUG METABOLISM - QUANTITATIVE STUDIESAbstracts are arranged alphabetically by first author

Quantitation of Levorphanol in Human Plasma by LC/MS/MS with APCI Interface;Quantitative determination ofCP-93,393 in plasma at trace levels by HPLCIMS/MS; *Avery, Mlchael; Fouda, Hassan;Pfizer!NC Groton, CTDetermination of astemizole and desmethylastemizole in human plasma at pg level by HPLC-MS-MS; *Beaudry,Francis; Coutu, Michel; Lessard, Denis; Le Blanc, Yves; Phoenix International, 4625 Dobrin St., St-Laurent (Quebec) H4R2P7, CanadaDevelopment of A Sensitive (LCIMSIMS) Assay for the Antitumor Agent 9-Aminocamptothecin; *Belas, Frank; Arora,Vinod; Goldthwaite, Charles; DeVore, Russell; Blair, lan; Department of Pharmacology, Vanderbilt University School ofMedicineDetermination ofZD6169 in Human Plasma by LC-APCIIMS/MS: Comparison to a Traditional LCIUV Method; *Bui,Khanh; Gao, Vince; Raybuck, Deborah ; Dyroff, Martin; Birmingham, Bruce; Zeneca PharmaceuticalsQuantitative Analysis of the Vasopressin Antagonist, SR 49059, in Human Plasma Using APC) LC-MS/MS; *Burton,Regina D.; Mummert, Michael; Braithwaite, Frances; Smith, David I.; Ellames, George J.; Newton, John F.; Wu, Danlin;Clinical Pharmacokinetics & Metab., Sanofi Research Division, Malvern, PALC-MSIMS Method for Profiling Nicotine and its Metabolites in Biological Fluids; *Byrd, Gary; R. J. Reynolds TobaccoCompany, Winston-Salem, NCLCIMS/MS Determination ofOndansetron conjugates in Human Urine; *Campbell, Victoria; Henion, Jack; **Walsh,John; Advanced BioAnalytical ServicesInvestigation of 4-Phenylbutyric Acid and its Metabolites using GCMS; *Candelario, Alexander; Stone, Earle; Bach,Stephan; Streeper, Robert; The University of Texas at San AntonioPicogram Determination ora Novel D4 Receptor Antagonist in Human Plasma and Urine by LC-APCI MS-MS;*Chavez-Eng, Cynthia; Constanzer, Marvin; Matuszewski, Bogdan; Merck Research Laboratories, West PointAn LCIMSIMS Method for Quantitation ofWellbutrin and its Metabolites in Human Plasma; Dunn, John; Otto,Victoria; Kenney, Kathryn; Smith, Glenn; Long, Joe; Singh, Ashish; *Allsup, Thurman; Glaxo Wellcome Research TrianglePark, NCHPLC-MSIMS Quantification of a 5-HTIa Antagonist and Its Metabolite in Rat Brain by Microdialysis; *Heath,Timothy; Scott, Dennis; Hoechst Marion RousselAnalysis of nifedipine (NIF) by LC-MSIMS in plasma to develop new safe clinically NIF formulations; *Kinzig, Martina;R'9'sing, Guido; Ssrgel, Fritz; IBMP - lost. f. Biomed. and Pharmaceut. Res., N'9'rnberg-Heroldsberg, GermanyHigh pressure CID spectra of isoflavonoids and application to analysis of isoflavones in plasma; *Kirk, Marion; Coward,Lori; Bames, Stephen; University ofAlabama at Birmingham, Birmingham, AL 35294Determination ofSCH 51866 in Micropig Plasma via LC-APCIIMSIMS; *Korfmacher, Waiter; Veals, John; Zhang,Xiping; Watkins, Robert; Cook, John; Tedesco, Richard; Lin, Chin-Chung; Schering-Plough Research Institute, KeniIworth,NJDetermination of3,4-dihydroxyphenylacetic acid (DOPAC) in equine urine by ion-spray Le-MS; *Koupai-Abyazani,Mohammed; Esaw, Barbara; Laviolette, Barbara; Can Test Ltd., 1523 West 3rd Avenue., Vancouver, B.C., V6J !J8,CANADAQuantitation ofEcteinascidin 743 in Blood by Mass Spectrometry; Lau, Sharon; *Rinehart, Kenneth; University ofIl1inois, Champaign-UrbanaQuantification of Intact Selegiline and Three metabolites in human Plasma Using Electrospray MSIMS; *Li, Qimin;McKay, Gordon; Midha, Kamal; College of Pharmacy & Nutrition, University of Saskatchewan, sm 5C9 Canada


ThPH Quantitation of rapamycin: Comparison between curtain-gas and heated capillary API interfaces; * Lirn, H.K.; Cinque,T.; Cantone, J.; Gu, H.; Osman, M.; Stroshane, R.; Sisenwine, S.; Chan, K.; Wyeth-Ayerst Research

ThPH The Quantitation of Cyclosporin A in Dog Blood using Electrospray LC-MS/MS; *Luo, Wendy C.; Vekich, Sylvia \T.;Rudewicz, Patrick J.; Allergan, Irvine

ThPH Validation of a LC/MS method for quantifying MDL 100,907 and its metabolite, MDL 105,725, in plasma; *McElvain,James; Perkins, Pamela; Vandiver, Val; Eichmeier, Larry; US Bioanalytics Dept., Hoechst Marion Roussel

ThPH The validation of a quantitative assay for Tirilazad Mesylate and two metabolites in five species; *Moore, Theresa A.;Hauer, Michael J.; Drug Metabolism Research, Pharmacia & Upjohn, Inc., Kalamazoo, MI 49001

ThPH Determination ofSelegiline, Desmethylselegiline and Related Compounds in Human Plasma by LC/MS/MS; *Mulvana,Daniel E; Perkins, John; Henion , Jack; "Damow, John; Bell, Robert; Advanced BioAnalytical Services, Ithaca, NY

ThPH Quantitative Analysis ofTaxol in Plasma by lonspray LC-MS/MS; *Murakami, Stanley; Bethem, Robert; Fukuda, Elaine;ALTA Analytical Laboratory, El Dorado Hills, CA 95762

ThPH The Determination of the Anti-convulsant 534U87 in Human Plasma by Automated SPE and LC-MS-MS; *Pleasance,Stephen; Biddlecombe, Robert A.; Jones, Anne E.; Eaves, C. Jane; G1axoWellcome

ThPH Quantitative Analysis of the NKl Receptor Antagonist, SR 140333, in Human Plasma Using LC-MS/MS; *Price, PiperI.; Buhrman, Deborah L.; Burton, Regina D.; Sirnpson, Heidi; Herbert, John M.; Ellames, George 1.; Newton, John F.; Drozd,Marion L.; Clinical Pharmacokinetics & Metab., Sanofi Research Division, Malvern, PA

ThPH Quantitation of Muscle Relaxants in Plasma using HPLClTandem Mass Spectrometry; Rindgen, Diane; *Marzilli, Lisa;Martyn, Jeevendra; Vouros, Paul; Northeastern University, Bamett Institute, Boston, MA 02115

ThPH Sensitive measurement of erythromycin A and its byproducts in tablets and plasma using LC-MS/MS; *RYsing, Guido;Kinzig, Martina; Haag, Armin; Ssrgel, Fritz; IBMP - lnst. f. Biomed. and Pharmaceut. Res., NYrnberg-Heroldsberg, Germany

ThPH Quantification ofCP-116,517 and its Metabolite CP-114,099 from Human Plasma by HPLCIESI /MS/MS; *Schneider.Richard; Hoffmaster, Keith; Fouda, Hassan; Central Research Division, Pfizer Inc, Groton, CT 06340

ThPH Flow-Injection ESI (MS/MS) ofPCV-TP & ACV-TP in Extracts ofa Herpesvirus-Infected Neural Cell line; *Smyrnis,Elie, M.; Sacks, Stephen, L.; Burton, Roland; Abbott, Frank; University of British Columbia, Vancouver, Canada

LASER DESORPTION - INSTRUMENTATIONAbstracts are arranged alphabetically by first author

ThPI Optically Isolated Microchannel Plate Detector Module for High Voltage Postacceleration of MALDI Ion; *Benner, W.Henry; **Horn, David; Lawrence Berkeley National Laboratory

ThPI A Bench-Top MALDI-ToF for the Rapid Sequencing of Peptides and Proteins; Bowdler, Andrew R; Dingley, David C;*Humphrey, Paul; Kratos Analytical, Barton Dock Road, Manchester/Md l 7LD, UK.

ThPI Enhancement of MALDI-TOF MS and MS/MS performance using Delayed Extraction; *Brown, J. M.; Bateman, R. H.;Critchley, W. G.; Hoyes, J. B.; Kingston, R. G.; VG Organic, Manchester, M23 9LZ, UK

ThPI Delayed Extraction and Laser Desorption: Time-lag Focusing and Beyond.; *Colby, Steven M.; Scientific InstrumentServices, Inc.

ThPI Post-Source Decay Without Scanning the Reflectron: Applications to Biomolecules.; *Cordero, M.M.; Woods, A.S.;Cornish, TJ.; Cotter, RJ.; Pharmacology, Johns Hopkins University Medical School, Baltimore MD

ThPI MALDIIMS and the Aging Process: Oxidative Protein Damage; *Deterding, Leesa; Barr, David; Mason, Ronald; Tomer,Kenneth; NIEHS, Research Triangle Park, NC

ThPI Fragmentation of phosphorylated peptides: MALDI on Time-of-Flight and FTMS Analyzers; *Gillece-Castro, Beth;Stults, John; Genentech, Inc. South San Francisco, CA

ThPI MALDI TOF MS Analysis ofGlycoproteins Using Delayed Extraction; *Karas, Michael; Bahr, Ute; **Tsarbopoulos,Anthony; Pramanik, Birendra N.; JW Goethe-Univ., Div. for Instrum. Analyt. Chem., 60590 Frankfurt, Germany

ThPI Sequence Analysis of Modified Oligonucleotides by MALDI Mass Spectrometry; Kosaka, Toshiyuki; *Kinoshita, Takeshi;Takazawa, Tomoko; Nakamura, Takemichi; Koizumi, Makoto; Hotoda, Hitoshi; Analytical and Metabolic ResearchLaboratories, Sankyo Co., Ltd., Tokyo.

ThPI Characterization of protein glycosylation by post source decay and exoglycosidase digestion; *Krogh, Thomas N.; Mi,rtz.Ejvind; Mirgorodskaia, Ekaterina; Roepstorff, Peter; H(jrup, Peter; Dept. of Molecular Biology, Odense University, DK-5230Odense M, Denmark

ThPI Delayed Ion Extraction for the Analysis of Metastable Fragmentation in MALDI-MS; *Luedemann, Hans-Christian;Stahl-Zeng, Jianru; Hillenkamp, Franz; Institute for Medical Physics and Biophysics, University ofMuenster

ThPI Characterization of Neutral Products in the Laser Photolysis of Monolayer Organosiloxane Films; *McElvany, Stephen;Friedli, Andrienne; Dulcey, Charles; Holliman, Christopher; Naval Research Laboratory, Washington, D.C.

ThPI Use oflmmobilized Enzymes and Delayed Extraction MALDI-TOF for Protein Characterization; *Patterson, Dale; Tarr,George; Hines, Wade; Vestal, Marvin; Martin, Stephen; PerSeptive Biosystems, Inc., Framingham, MA

ThPI Comparison of cm and PSD Data Obtained from Tryptic Peptides Using Delayed Extraction MALDI-TOF MS;*Peltier, John; Waddell, Keith; Mark, 1.; Falick, Amold; PerSeptive Biosystems, Inc. Framingham MA 01701

ThPI Examination Of The Use OfMALDI In-Source Decay For Sequencing Peptides; *Reiber, Duane; Brown, Robert;Weinberger, Scot ; Komfeld, Rich; Kenny, James ; Utah State University, Logan, UT 84322-0300

ThPI Optimization of the Parameters Effecting MALDI Mass Resolution; *Russell, David H.; Edmondson, Ricky D. ; TexasA&M University, College Station

ThPI Characterization ofrecombinant annexin 1 domain 2 by MALDI-MS, mass mapping and PSD; *Shen, Tun-Li; Li, Vue;Yan, Hong-Gao; Gage, Douglas A.; Dept. of Biochemistry, Michigan State University, East Lansing, MI 48824

ThPI Disulfide Bonding in Biologically Active PeptideslProteins: A MALDI FT-ICR / MS Analysis; *Solouki, Touradj;Emmett, Mark, R.; Guan, Shenheng; Marshall, Alan G.; National High Magnetic Field Lab, Florida State U., Tallahassee FL


ThPI Biopolymer sequencing by MALDI-TOF MS; *Suckau, Detlev; Ksster, Claus; Holle, Annin; Bruker-Franzen AnalytikGmbH, Bremen

ThPI Accurate Mass Measurements Using Delayed Extraction MALDI Time-of-Flight Mass Spectrometry; *Takach, Edward;Patterson, Dale; Hines, Wade; Juhasz, Peter; Lee, Richard; Vestal, Marvin; Martin, Stephen; PerSeptive Biosystems, Inc.,Framingham, MA

ThPI Structural Analysis ofPeptidoglycans by MALDI-MS and PSD; *Xu, Naxing; Huang, Zhi-Heng; Watson, J. Throck;Gage, Douglas A.; **de Jonge, B.L.M. ; Severin, Anatoly; Tomasz, Alexander; Dept. of Biochemistry, Michigan StateUniversity, East Lansing, MI48824

LASER DESORPTION - APPLICATIONSAbstracts are arranged alphabetically by first author

ThPJ Fragmentation of Peptides Generated by MALD/I in a Linear Time-of-Flight Mass Spectrometer; Amft, Matthias;Finsterer, Roland; Damm, Monika; *Grotemeyer, JUrgen; Institut fUr Physikalische Chemie, Universitat WUrzburg

ThPJ Identification of pheromone binding proteins by MALDI and ESI after "PLC and native-PAGE; *Blais, Jean-Claude;**Nagnan Meillour, Patricia; Bolbach, Gerard; Tabet, Jean-Claude; Universit Pierre et Marie Curie - Paris

ThPJ MALDI-TOFMS investigation of peptide-protein interactions; *Bolbach, G rard; Blais, Jean-Claude; Brunot, Alain;**Girault, Sophie; Lavielle, Solange; Chassaing, G rard; Sagan, Sandrine; Universit P&M Curie, CNRS EP 103, PARIS

ThPJ Glycoprotein Analysis via MALDI TOF-MS and "PCE Coupled with off-line MALDI TOF-MS; *Chakel, John;Hancock, William; Udiavar, Sharmila; **Swedberg, Sally; Biomeasurements Group, Hewlett-Packard Laboratories, Palo Alto,CA 94304

ThPJ Micro-Spot MALDI for Ultrasensitive Detection of Nanoscale Samples; *Golding, Rafael; Whittal, Randy; Li, Liang;Department of Chemistry, University of Alberta

ThPJ MALDI-TOF/MS for the Analysis of Potential Blood Substitutes; *Gu, Xiaomei; Kondubhotla, Sujatha; Aldridge, Allison;Chiarelli, Paul; Olsen, Kenneth; Depatment of Chemistry, Loyola University-Chicago, Chicago, IL 60626

ThPJ TLCIMALDI: principles and applications.; *Gusev, Arkady I.; Mehl, John T.; Wilkinson, William R.; Nicola, Anthony J.;Vasseur, Olivier J. ; Hercules, David M.; Department of Chemsitry, Vanderbilt University, Nashville, TN 37235

ThPJ External Ion Injection for the "PLC-Liquid MALDI in an Ion traplTOF Mass; *He, Ling; Chen, Xin; Lubman, DavidM.; Chemistry Dept. University of Michigan Ann Arbor, MI 48109-1055

ThPJ MALDI: Preserved solution/solid-phase peptide-metal ion interactions without gas-phase interactions; *Hornshaw,Martin; Hutchens, T.William; University of California, Davis

ThPJ MALDI-MS of peptides and proteins offstreptavidine-coated magnetic beads; Larsen, Martin Roessel; *Nordhoff,Eckhard; Gerdes, Kenn; Roepstorff, Peter; Department of Molecular Biology, University of Odense, Denmark

ThPJ Analysis of a Pentameric Complex of Cholera Toxin B-subunit by MALDI-TOF and Electrospray MS; **Mandel,Friedrich; Dragovic, Marina; ·Raverdino, Vittorio; Analytical lab Hewlett-Packard, rue Veyrot 39, Geneva, Switzerland

ThPJ Mass spectrometric characterization of glycoproteins separated by gel electrophoresis.; ·Ml,rtz. Ejvind; **Krogh,Thomas N.; H(jrup, Peter; Roepstorff, Peter; Dept. of Molecular Biology, Odense University, DK-5230 Odense M, Denmark

ThPJ A Novel Laser Microprobe QITMS for Imaging of Drug Compounds in Intact Biological Tissue; ·Reddick, ChristopherD.; Yost, R.A.; University of Florida

ThPJ Experiences in sample preparation for MALDI from the Protein Research Group at the Odense University;·Roepstorff, Peter; Nielsen, Henrik R.; Larsen, Martin R.; Haebel, Sophie; Jensen, Charlotte; ··Palm, Lisbeth; Krogh ,Thomas; Mirgorodskaya, Ekatarina; Department of Molecular Biology, Odense University, Denmark

ThPJ Examination of Approaches for Application ofMALDI as an On-Line Biological Detection Technique; ·Steadman,Jhobe; Roser, Dennis; ··Long, Randolph; GeoCenters, Fort Washington, MD

ThPJ Semi-Automated Sample Analysis Using Liquid Chromatography/MALDI Mass Spectrometry; ·Stevenson, Tracy I.;Loo, Joseph A.; Parke-Davis Pharmaceutical Research, Ann Arbor, MI

ThPJ MALDI MS of Proteins Adsorbed to Modified and Unmodified Polymer Substrates; ·Walker, Angela K.; Kinsel, GaryR.; Timmons, Richard B.; Wang, Y.-S.; Dept. of Chemistry, The University of Texas at Arlington, Arlington, TX

ThPJ Use of Synthetic Membranes to Prepare Proteins, Oligonucleotides, and Digests for MALDI-TOF Analysis; ·Worrall,Timothy A.; Woods, Amina S.; Cotter, Robert J.; Pharmacology, Johns Hopkins University Medical School, Baltimore MD

ThPJ Mercaptobenzothiazoles: New Matrices for Laser Desorption Ionization Mass Spectrometry; ·Xu, Naxing; Huang, ZhiHeng; Gage, Douglas; Watson, J. Throck; Dept. of Biochemistry, Michigan State University, East Lansing, MI48824

ThPJ In Vivo Study of the Oxidation of Substance P in Rat Brain by MicrodialysislMALDI MS; ·Zhang, Hong; Caprioli,Richard; University ofTexas Medical School, Houston, Texas 77030

SPRAY IONIZATION - APPLICATIONSAbstracts are arranged alphabetically by first author

ThPK Characterisation of water soluble Rotaxanes by Electrospray Ionisation Mass.Spectrometry.; Anderson, Harry;Andesrson, Sally; ·Aplin, Robin; The Dyson Perrins Laboratory.Oxford University.Oxford, UK. OXI3QY

ThPK The Determination of Protein Modifications by Precursor Ion Scans of Proteolytic Digest Mixtures; ·Bourell, James;Stults, John; Genentech, Inc., South San Francisco, CA 94080

ThPK Probing the Oligomeric Structure of an Enzyme by ESI-TOFMS; ·Fitzgerald, Michael, C.; Chernushevich, Igor; Standing,Kenneth, G.·1-2; Whitman, Christian, P.; Kent, Stephen, B.·1-2; The Scripps Research Institute, La Jolla, CA

ThPK Analysis of Cobalt Coordinated High Mannose Oligomers using Ion Trap Mass Spectrometry; ··Gale, David C.;Sweeney, Matt, J.; Kohler, Martin; *Leary, Julie A.; College of Chemistry, University of California, Berkeley, CA 94720

ThPK Ternary complexes oftripeptides with copper(11) and diimine in the gas phase.; Gatlin, Christine; Turecek, Frantisek;*Vaisar, Tomas; Molecumetics Ltd* and Dept. of Chemistry, University of Washington


ThPK Negative Ion Electrospray Mass Spectra of Fullerene Derivatives; ·Haller, Ivan; Mina, Urooj A.; Chait, Brian T.;Tokuyama, H.; Strongin, R. M.; Smith, Amos B., Ill; The RockefeIler University, New York, NY 10021

ThPK Direct Quantitation of Methyl Succinate by Electrospray Negative Ion Tandem Mass Spectrometry; .Ketcha, MarciaM.; Strife, Robert J.; The Procter and Gamble Co.

ThPK 'Noncovalent Complexes ofCitrate Synthase and NADH.; ·Krutchinsky, Andrew N.; "Ayed, Ayeda; Chemushevich, IgorV. [1); Ens, Wemer E. [I]; Duckworth, Harry E. [2]; Standing, Kenneth G. [I]; University of Manitoba, Physics Dept.,Winnipeg Manitoba Canada R3T 2N2

ThPK Characterization and formation studies ofsynthetic supramolecular complexes by ESMS; ·Leize, EmmanueIle; Dupont,Annick; Marquis-Rigault, Annie; Baxter, Paul; Lehn, Jean-Marie; Van Dorsselaer, Alain; Laboratoire de Spectrom trie deMasse Bio-Organique - Strasbourg (France)

ThPK Analysis of trypsin-inhibitor complexes by electrospray/mass spectrometry; ·Lin, Baiwei; Traina, Joe; Liang, Amy; Light,David; Berlex Biosciences

ThPK ESI-MS Characterization of Zinc Ejection from HIV-I Nucleocapsid Protein by Disulfide Benzamides; ·Loo, Joseph A;Parke-Davis Pharmaceutical Research, Ann Arbor, MI

ThPK Electrospray Ionization Mass Spectra ofCarbocyanine Dyes Used as Molecular Probes; ·Melnyk, Michael; Busch,Kenneth; Bartlett, Michael; School of Chemistry & Biochemistry, Georgia Inst. of Technology, Atlanta GA

ThPK Additive Enhancement for Electrospray Ionization of Nitrated Explosives; ·MilIer, Mark L.; Leibowitz, Jeff; Martz,Roger; FBI Laboratory, FBI Academy, Quantico, VA 22135

ThPK Optimization orESI Conditions for Detection of Non-Covalent Complexes ofCalmodulin with Peptides; ·Nemirovskiy,alga; Gross, Michael; Ramanathan, Ragulan; Chemistry Department, Washington University, St. Louis, MO 63130

ThPK Analyses of Coenzyme BI2 Derivatives and Complexes with Non-Covalent Bondings by using ESI-MS; ·PeIlascio,Bemhard C.; Pfammatter, Michael J.; Schlunegger, Urs P. ; Institute of Organic Chemistry, University of Bern, CH-3012 Bern

ThPK Detection of glycosylated and phosphorylated peptides by LC-MS using API-CID and in-source CID; ·Seipelt, C.Thomas; CaldweIl, Brenda E.; Pound, Vickie L.; Abbott Laboratories - Ross Products Division

ThPK Purity of Polysui fated Materials Determined by Negative ESIIMS; ·Siegel, MarshaIl; Tabei, Keiko; "Kagan, Michael;Wyeth-Ayerst Research, Pearl River, NY

ThPK Regulation of Multimer Formation in API-MS; ·Stefansson, Morgan; Sjsberg, Per J. R.; Bylund, Dan; Markides, Karin E.;Dept. of Analytical Chemistry, Uppsala University

ThPK Inclusion complexes versus electrostatic adducts in electrospray and capillary zone electrophoresis; ·Suter, Marc J.-F.;Kanz, Carlo; Giger, Waiter; Kohler, Hans Peter; Swiss Federal Institute for Environmental Science and Technology (EAWAG)

ThPK An Investigation ofCyclodextrin-Drug Complexes: True Complexes or Electrostatic Adducts?; ·Visentini, Josie;Bertrand, Michel; "Gagnon, Helene; Rousseau, Caroline; Winters, Conrad; Merck Frosst Centre for Therapeutic Research,Kirkland, Quebec

ThPK Determination the unstable intermediates from organic reactions by low temperature ESIIMS and FABIMS; Wang,Chin-Hsiung; Chei, Hsing-Long; ·Shiea, Jentaie; Dept. of Chemistry, National SunYat-sen University, Kaohsiung,Taiwan,804

ThPK The Study of the structure ofthe ligands to the folding of protein by ESIIMS; Wang, Yu-Ting; ·Shiea, Jentaie; Dept. ofChemistry, National Sun Yat-sen University, Kaohsiung, Taiwan, 804

ThPK Cyclic nucleotide quantitation in biological samples using IS-HPLC coupled to ES-MSMS.; ·Witters, Erwin; VanDongen, Waiter; "Esmans, Eddy; Van Onckelen, Harry; Department of Biology, University of Antwerp (U.I.A), Antwerp

ThPK Use of ESI-FTICR-MS to rapidly detect taxonomically significant double stranded PCR products.; ·Wunschel, David;"Muddiman, David; Bruce, James; Fox, Karen; Fox, Alvin; Smith, Richard; University of South Carolina, School ofMedicine, Columbia, South Carolina

ThPK Metal Ion Flux in Metalloprotein-Drug Reactions; ·Zaia, Joseph; Fabris, Daniele; Fenselau, Catherine; University ofMaryland, Baltimore County

ThPK Protein Fragmentation in ESI Induced by the Auxiliary Gas; Analysis of the Data by MaxEnt; ·Zhang, X. Kate; Dutky(dec.), Robert C.; Derua, Rita; Ferrige, Anthony G.; Fales, Henry M.; National Heart, Lung, and Blood Institute,NIH,Bethesda, MD

AFFINITY-BASED SEPARATION AND INTERACTIONSAbstracts are arranged alphabetically by first author

ThPL Mass spectrometric characterization oCthe active and inactive form oCRas protein; ·Akashi, Satoko; Shirouzu, Mikako;"Yokoyama, Shigeyuki; Takio, Koji; The Institite of Physical and Chemical Research (RIKEN)

ThPL Selective Detection of AldehydelPeptide Adducts Using Affinity Extraction and Tandem MS Screening; ·Bolgar, Mark;Gaskell, Simon; The Michael Barber Centre for Mass Spectrometry, UMIST, Manchester

ThPL New Chemistries for Probe Affinity-Mass Spectrometry; ·Brockman, Adam; Orlando, Ron; CCRC, University of Georgia,Athens, GA, 30602

ThPL Bioaffinity Characterization MS ofPhosphopeptide Binding to Human Src SH2 Domain; ·Bruce, James E.; "Carr,Steven A.; Anderson, Gordon A.; Pasa-Tolic, Ljiljana; Hofstadler, Steven A; Smith, Richard D.; Pacific Northwest NationalLaboratory, Richland, WA

ThPL Determination of §-agonists in Bovine Urine by Immunoaffinity Extraction-LCILCIMSIMS; ·Cai, Jenny; Henion, Jack;Comell University

ThPL Probing non-covalent complexes of tyrosyl phosphopeptides and an SH2 domain by ESI MS; ·Chung, Evonne; Mulhem,Terry; Morton, Craig; Robinson , Carol; Oxford Centre for Molecular Sciences

ThPL Epitope mappings of maillard reaction products using LCIESIMS; ·Hirayama, Kazuo; Tagami, Uno; Yamada, Naoyuki;Yuji, Reiko; Kazuyoshi, Noguchi; "Toshimitsu, Niwa; Central Research Laboratories, AJINOMOTO Co., Inc.


ThPL Continuous Epitope Mapping by On-line Capillary Electrophoresis- ESI Mass Spectrometry; Lyubarskaya, Yelena;·Dunayevskiy, Yuriy M.; Vouros, Paul; Karger, Barry L.; The Barnett Institute, Northeastern University, Boston, MA

ThPL Protein epitope identification using limited proteolysis of immune complexes and massspectrometry; ·Macht, Marcus;"KUrzinger, Konrad; Przybylski, Michael; University of Konstanz, PO Box 5560 M 732,78434 Konstanz, Germany

ThPL Determination ofthe sites of interaction between the formyl peptide receptor and its ligand.; ·MiIIs, John; Barnidge,David; Dratz, Edward; Jesaitis, Algiidas; Montana State University, Bozeman MT

ThPL Characterization of the pore-forming aerolysin toxin non-eovalent complex by MALDI-TOF MS; ·Moniatte, Marc; vander Goot, F. Gisou; Buckley, J. Tom; Pattus, Franc; Van Dorsselaer, Alain; Laboratoire de Spectrom trie de Masse BioOrganique, ULP, Strasbourg

ThPL Identification ofa Noncovalent Trimer ofCatifish Roe Lectin by Centrifugation and MassSpectrometry; ·Murayama,Kimie; Taka, Hikari; Kaga, Naoko; Shindo, Noriko; Hosono, Masahiro; Nitta, Kazuo; Cent. Lab. of Med. ScL JuntendoUniv.Sch. of Med. Tokyo Japan .

ThPL Structural Immunology by MALDI/MS: Epitope Determination on AIDS Related Proteins; Parker, Carol; Trojak, Sonja;·Tomer, Kenneth; National Institute of Environmental Health Sciences

ThPL Study of non-eovalent enzyme/cofactor and enzyme/inhibitors complexes by ESI-MS; Potier, Noelle; Barth, Patrick;Trisch, Denis; Biellmann, Jean-Francois; ·Van Dorsselaer, Alain; Laboratoire de spectrometrie de masse bio-organique

ThPL Probing the nature of non-eovalent protein ligand interactions; ·Robinson, Carol; Chung , Evonne; Kragelund, Birthe;Knudsen, Jens; Dobson, Christopher; Oxford Centre for Molecular Sciences

ThPL Study of Non-eovalent Interactions and HID Exchange using Micro Electrospray; Robinson, Carol; ..Jarvis, Stuart;·Chung, Evonne; Hughes, Christopher; Green, Brian; Oxford Centre for Molecular Sciences, Oxford, UK.

ThPL Studying Drug Binding to the Noncovalent Tat Peptide-TAR RNA Complex by ESI-MS; ·Sannes, Kristin A.; Mei,Houng-Yau; Made, David; Loo, Joseph A.; Parke-Davis Pharmaceutical Research, Ann Arbor, MI

ThPL Interaction studies combining plasmon resonance in a BlAcore instrument with MALDI- and nano ESI-MS; Ssnksen ,Carsten P; ••Jansson, ... sten; Stenberg, Esa; ·Roepstorff, Peter; Department of Molecular Biology, University of Odense,Denmark

ThPL MALDI Mass Tracer Methods Based on the Avidin-Biotin Interaction; ·Schriemer, David C.; Li, Liang; University ofAlberta, Edmonton, Alberta, Canada

ThPL FT ICR Investigation of Supramolecular Propellers ofChiral Dialkyltartrate Trimers; ·Winkler, F. Johann; Denisov,Edward V.; Medina, Ramiro; Schustrjalcov, Valerij; Vinogradov, Pavel S.; Nikolaev, Eugene N.; Institut f. Chemie, Techn.Univ. Muenchen, D-85350 Freising, Germany

ThPL Comparison of Solution and Gas Phase Binding Affinities of Inhibitors to Carbonic Anhydrase; • Wu, Qinyuan; Gao,Jinming; Bruce, James E.; Sigal, George B.; Whitesides, GeorgeM; Smith, Richard D.; Pacific Northwest NationalLaboratory

ThPL Affinity Mass Spectrometry for the Study of Signal Transduction; ·Yip, Tai-Tung; Hutchens, T. William; Dept of FoodSci & Tech, U of California, Davis, CA956I6

ThPL MALDIItime-of-tlight MS analyses of antigens after immunoaffinity extraction from whole celllysates; Vu, Lu;"Brookman, Jayne L.; ·Gaskell, Simon J.; Michael Barber Centre for Mass Spectrometry, UMIST, Manchester, U.K.


ThPM Beta-Endorphin-Containing Proteins in Human Pituitary; • Becklin, Robert; Van, Lin; Chu, Jasper; Tseng, Jih-Lie;Desiderio, Dominic; Stout MS Lab. University ofTenessee, Memphis.

ThPM Locating hemes in cytochrome busing MALDI-TOF mass spectrometry; ·Barnidge, David; Sunner, Jan; Dratz, Edward;Mills, John; Jesaitis, Algirdas; Montana State University

ThPM Investigation of the Interactions Between 4-Hydroxynonenal and Lysine Residues of Proteins; ·Bolgar, Mark; Gaskell,Simon; The Michael Barber Centre for Mass Spectrometry, UMIST, Manchester

ThPM Determination ofoxidation sites in alpha crystallin by ESI-MSIMS; ·Busman, Mark; Finley, Eric L.; "Dillon, Jim;Crouch, Rosalie K.; Schey, Kevin L.; Dept. of Pharmacology, Medical Univ. of South Carolina, Charleston, SC

ThPM Direct Characterization of Proteins from Organisms with Small Genomes; ·Carmack, Edwin; Hays, Lara; Link, Andrew;Yates, John R.; University of Washington, Seattle, WA

ThPM Investigation of binding of SSB to DNA by competitive labeling and mass spectrometry; ·Chen, Jiwen; Griep , Mark A.;Smith, David L.; Department of Chemistry, University of Nebraska, Lincoln, NE 68588

ThPM Detection of the specific binding site between NM23-H2 and human e-mye gene by LC/MS; ·Chen, Yajuan; Qian, MarkG.; Bai, Jian; Zheng, Kefei; Chang, Christina L.; Lubman, David M.; The Univeristy of Michgain, Ann Arbor

ThPM A Study of Possible Breast Cancer Markers Using 2D-PAGE Combined with Tandem Mass Spectrometry; .Clarke,Nigel J.; Tomlinson, Andy J.; Naylor, Stephen; Mayo Clinic, Rochester, MN 55905, USA

ThPM Analysis of purified human serum albumin by electrospray ionization mass spe.ctrometry; ·Cyr, Terry Donald; Girard,Michel; Bietlot, Henri; Health Protection Branch, Drugs Directorate, Bureau of Drug Research

ThPM The Identification of the Disulfide Bonds in the Circulins, a Group ofAnti-HIV Circular Peptides; .Derua, Rita;Gustafson, Kirk; Hallock, Yali; Pannell, Lewis; Laboratory ofAnalytical Chemistry, NIDDK, NIH, Bethesda MD 20892-0805

ThPM Sequencing of Glucokinase from Bacillus stearothermophilus by Tandem ESI-FTICRMS; ·Dufresne, Craig; Wood,Troy; State University ofNew York at Buffalo, Buffalo, NY

ThPM Characterization ofBSA based immunogens by MALDI and ESI mass spectrometry; ·Gebler, John; Adamczyk, Maciej;Mattingly, Phillip; Abbott Laboratories, Abbott Park, IL

ThPM The amino acid sequence of a copper-binding metallothionein isolated from Helix pomatia snails; ·Gehrig, Peter;Hunziker, Peter; "Berger, Burkhard; Dallinger, Reinhard; Biochemisches Institut der Universitat ZUrich, ZUrich, Switzerland


ThPM Identification of a Murine Colorectal Tumor Antigen by Tandem Mass Spectrometry; *Gulden, Pamela; Huang, Alex;Shabanowitz, Jeffrey; Wang, Wei; Engelhard, Victor; Jaffee, Elizabeth; Pardoll, Drew; Hunt, Donald; University ef Virginia,Charlottesville, VA

ThPM Identification of an Alloantigen by Tandem Mass Spectrometry; *Gulden, Pamela; Wang, Wei; Shabanowitz, Jeffrey;Engelhard, Victor; Hunt, Donald; University of Virginia, Charlottesville, VA

ThPM Investigation of Lens Proteins with High Cysteine Content; *Hanson, Stacy R.A.; Smith, Jean B.; Smith, David L.;Department of Chemistry, University of Nebraska-Lincoln

ThPM Location of Oxidized Residues in Bovine alpha-Crystallins by HPLCIESIIMS and CF-FAB MSIMS; *Jiang, Xiangyu;Smith, Jean B.; Smith, David L.; Abraham, E. C.; Department of Chemistry, University ofNebraska-Lincoln, Lincoln, NE68588

ThPM Proteolytic Processing of a 44-mer Ovalbumin Peptide by the Murine Proteasome; *King, Gina M.; Niedermann, Gabi;Shabanowitz, Jeffrey; Hunt, Donald F.; Eichmann, Klaus; University of Virginia, Charlottesville, VA

ThPM Characterization of insect diuretic hormone proteolysis using RP-HPLCIESI-MS; *Li, Hong; Wang, Houle; Schegg,Kathy; Schooley, David; University of Nevada, Reno, NV 89557

ThPM Application of on-line CE-ESI-ITrrOF in the analysis of Variant Hemoglobin; *Li, Michael, X.; Wu, Jingtao; Liu, Lin;He, Ling; Lubman, David M.; Univ. of Michigan

ThPM Isolation and Structural Determination of Modified Human Alpha-Crystallins by lEX, LC-MS and MS/MS; *Lin,Peiping; Smith, Jean; Smith, David; Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588'

ThPM ESI-MS evaluation of post-translational modifications to histone proteins through the cell cycle; *Lipton, Mary S. Weir;Springer, David L.; Metting, Noelle F.; Edmonds, Charles G.; Pacific Northwest National Laboratory

ThPM Fast Detection of Peroxisomal Protein Mutants by CEIMS; *Liu, Lin; Li, Michael, X.; Wu, Jingtao; Lin, Yan; OrIson,Laura; Lubman, David M.; University of Michigan, Dept. of Chem.

ThPM Identification of in vivo modifications of water insoluble human lens alpha-crystallins; *Lund, Anders L.; Smith, JeanB.; Smith, David L.; Department of Chemistry, University of Nebraska, Lincoln, NE 68588-0304

ThPM Tandem Mass Spectrometry: Analysis of Endogenous Peptides Presented by MHC Class 11I-Ab Molecules;*McConnack, Ashley; DeRoos, Paul; Grubin, Cathy; Rudensky, Alexander; Yates, John; University of Washington

ThPM The human male-specific histocompatibility antigen H-Y is derived from the SMCY protein; *Meadows, Leslie; Wang,Wei; den Haan, Joke; Sherman, Nicholas; Shabanowitz, Jeffrey; Hunt, Donald; Goulmy, Eis; Engelhard, Victor; University ofVirginia

ThPM Glutathione-S-Transferase Heterogeneity in Human Tissue Analyzed by ESI-MS; *Nieves, Edward; Rowe, Jonathan D.;Listowsky, Irving; Albert Einstein College of Medicine

ThPM Capillary LC/IT/reTOF MS for Structural Confirmation of Three Recombinant Protein Isoforms; *Qian, Mark G.;Zheng, Kefei; Chen, Yajuan; Chang, Christina L.; Lubman, David M.; The University of Michigan, Ann Arbor

ThPM Structural studies ofHIV related proteins using MALDIIMS; *Qian, Xiao-Hong; Parker, Carol; Bienstock, Rachelle;Jeyarajah, Shanthini; Tomer, Kenneth; National Institute of Environmental Health Sciences

ThPM Electrospray Mass Spectrometry of the Human S100 Proteins Calgranulin A, B and C.; *Raftery, Mark; Geczy, Carolyn;Immunology Group, The Heart Research Institute.

ThPM Covalent modification of rho protein by the antibiotic, bieyclemyein; Riba, Isabel; *Gaskell, Simon J ; Park, Hyeunggeun; Zhang, Xiangdong; Widger, William R; **Kohn, Harold; Michael Barber Centre for Mass Spectrometry, UMIST,Manchester, U.K.

ThPM Mass Spectrometric Analysis of the Lens Membrane Protein MP26; *Schey, Kevin L.; Fowler, John G.; **Dillon, Jim;Crouch, Rosalie K.; Dept. of Pharmacology, Medical Univ. of South Carolina, Charleston, SC

ThPM Analysis of Proteins in the 80S Ribosomal Complex ofS. cerevisiae by Mass Spectrometry; *Schieltz, David M.; Eng,Jimmy K.; Yates Ill, John R.; University of Washington, Seattle, WA

ThPM Characterization of Covalent Modifications in a Viral Protease by ESI-MS and MALDI-TOFMSj *Sheeley, Douglas;Wright, Lois; Furfine, Eric; Moyer, Mary; Glaxo Wellcome Research Laboratories, RTP, NC 27709

ThPM Characterization of Human Cytomegalovirus Protease (28 kDa) and Inhibitors by ESIIMS; *Siegel, Marshall; Tabei,Keiko; Bebernitz, Geraldine; Hulmes, Jeffrey; Ding, Wei-Dong; Baum, Ellen; Wyeth-Ayerst Research, Pearl River, NY

ThPM Identification of a Poliovirus RNA Translation Protein Using Data-Controlled LCIMSIMSj *Swiderek, Kristine M.;Blyn, Lawrence 8.; Stahl, Douglas C.; Beckman Research Institute of the City of Hope, Duarte, CA 91010

ThPM Mass Spectrometric Analysis ofthe Sf9 Cell-Derived Interleukin-5 Receptor; *Tsarbopoulos, Anthony; Prongay,Andrew; Baldwin, Sam; Kumarasamy, Ramasamy; Pramanik, Birendra; Le, Hung V.; Karas, Michael; Hillenkamp, Franz;Schering-Plough Research Institute, Kenilworth, NJ 07033-0539

ThPM Characterization of CMP-NeuAc Synthetase and its CTP-Binding Site by ESI and MALDI-MS; Tullius, Michael;*Gibson, Bradford; **Munson, Robert; University of California, San Francisco, CA 94143-0446

ThPM Characterisation of the Proteolytic Sites of Proteases Isolated From P. gingivalis W50j *U., S.; Sutton, C. W.;**Rangarajan, M.; Thermo BioAnalysis Ltd., Hemel Hempstead, UK

ThPM Formation and Stabilization of MHC Class II-Peptide Complexes: Results of a MALDI Study; *Vidavsky, lIan;Whitehill, Andy B.; Gross, Michael L.; Nelson, Chris A..; Unanue, Emil R.; Department of Chemistry, Washington University,St. Louis, MO 63130

ThPM Characterization of Low Molecular Weight Chromium Binding Substance by MALDI FT-ICR MS; *Vining, Bryan; Li,Guo-Zhong; Solouki, Touradj; Guan , Shenheng; Marshall, Alan; Vincent, John; National High Magnetic Field Lab, FloridaState Univ., Tallahassee, FL

ThPM Identification of target antigens in Multiple Sclerosis; *Walker, Carthene B.; Shabanowitz, Jeffrey; Hunt, Donald F.;Snoke, Ken; Sette, Alex; University of Virginia, Department ofChemistry, Charlottesville, VA 2290I


ThPM Site of Acrylodan AdductFormation with FattyAcid BindingProtein and FKS06BindingProtein; *Williwnson, BrianL.; Tomlinson, Andy J.; Holmes, Michael W.; Kurian, Elizabeth; Silva, Norberto; Prendergast, Franklyn G.; Naylor, Stephen;Mayo Clinic, Rochester, MN 55905, USA

ThPM Rat kidneyglutathione8-transferase 1 subunits haveC-terminal truncations; Yeh, Horng-I; Lee, Jing-Yu; Tsai, Shu-Ping; Hsieh, Cheng-Hsilin; *Twn, Ming F.; Institute ofMolecular Biology, Academia Sinica, Taipei, Taiwan, ROC

44th ASMS conference on mass spectrometry and allied topics … · 2017-08-26 · 44th ASMS...

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