Conference guide

1st International Conference on Microfluidic Handling Systems

3Enschede, the Netherlands

Welcome to the 1st International Conference on Microfluidic Handling Systems

Dear colleagues,

Worldwide, accurate handling (e.g. dosing, measurement and control) of small and extremely small mass flow rates of both gases and liquids is becoming more and more important, driven by numerous economically important ap-plications in for instance semiconductor industry, analytical instrumentation, food, pharmacy, energy, bioanalytical systems, and micro reaction systems.

Therefore, we organised the 1st International Conference on Microfluidic Han-dling Systems, which provides an excellent opportunity to bring together sci-entists and engineers from academia, research institutes and companies to present and discuss the latest results in the field of microfluidic handling systems. The conference goals are to stimulate interaction and knowledge exchange between the delegates in a friendly atmosphere.

The focus of this conference is mainly on the technology, components, devices and systems that enable the application and biology in microfluidic systems. The most recent developments in the field of microfluidic sensors, actuators, interfaces, fluidic control systems and applications will be presented.

We are looking forward to seeing you at the MFHS2012 conference!

Kind regards,

Dr. Joost Lötters Prof. Gerald UrbanChair Co-chair

4 MFHS 2012

General InformationConference LocationThe MFHS 2012 conference will be held at Holland Casino EnschedeBoulevard 1945 1057511 AM Enschede

Please note that to enter the Holland Casino, you should:- be at least 18 years of age- have a valid ID with you (passport or ID card)

For information:E-mail: mfhs2012@utwente.nlPhone: +31 (0)64 282 9007Web: www.mfhs2012.org

Registration informationThe registration desk will be open on:Wednesday 10 October: 17:00 – 21:00Thursday 11 October: 08:00 – 17:00Friday 12 October: 08:00 – 09:00

Internet serviceFor those who have their computer or smartphone with them, a complemen-tary wireless connection will be available in Holland Casino.An iCal-file with the full program can be added to you digital calendar by adding http://goo.gl/p7212

Oral PresentationsAn oral presentation slot is 20 minutes, divided in 15 minutes presentation and 5 minutes discussion. The schedule for the oral presentations can be found in the programme.

Poster PresentationsThe poster size should be in the A0 format (1189 mm high x 841 mm wide) in portrait orientation. The poster stands are numbered, please place your poster at the stand corresponding to the poster number in the programme and please do not remove the number from the stand as this number will be used for the poster award.

5Enschede, the Netherlands

AddressesDinner ThursdayHotel Restaurant RodenbachParkweg 35, 7513AR EnschedePhone: +31 (0)53-480 02 00

MESA+ / TST lab tourUniversity of TwenteDrienerlolaan 5, 7522NB EnschedeParking at P3 on the university CampusPhone: +31 (0)64 282 9007 / +31 (0)53 489 4655

HotelsEden Hotel De BroeierdHengelosestraat 725, 7521PA EnschedePhone: +31 (0)53 850 6500Transit: Walk to busstop ‘UT/Bosweg’ and take bus 1 (direction Wesseler-brink to stop ‘Van Heekplein’. Or walk to busstop ‘De Broeierd’ take bus 9 (direction Enschede Centraal) to stop ‘Enschede Centraal’ and walk.

Eden Star HotelB.P. Hofstedestraat 50, 7551DG HengeloPhone: +31 (0)74 851 68 00Transit: Walk to Hengelo Station take a train to ‘Enschede Centraal’, walk.

Drienerburght (University of Twente)Drienerlolaan 5, 7522NB EnschedePhone: +31 (0)53 433 13 66 Transit: Walk to ‘UT/De Zul’, take bus 1 (direction Wesselerbrink) to ‘Van Heekplein’ and walk.

Hotel Restaurant RodenbachParkweg 35, 7513AR EnschedePhone: +31 (0)53 480 0200Transit option: 15 minute walk. Or walk to busstop ‘Volkspark’ and take bus 1 (direction Wesselerbrink) to stop ‘Van Heekplein’ and walk.

Hotel AmadeusOldenzaalsestraat 103, 7511DZ Enschede Phone: +31 (0)53 435 7486Transit: 10 minute walk.

6 MFHS 2012

Conference Sponsors

University of Twente

MESA+ Institute for Nanotechnology

Bronkhorst High-Tech B.V.

LioniX

Micronit Microfluidics

7Enschede, the Netherlands

Innovative Sensor Technology

Future Chemistry

HSG-IMIT, Institut für Mikro- und Informationstechnik

Micromachines — Open Access Journal from MDPI

Fluigent

Conference Sponsors

8 MFHS 2012

ProgrammeWednesday 10 October 201217:00 Registration18:00 Welcome Reception19:00 Demonstration / explanation of Roulette / Black Jack21:00 Closure

Thursday 11 October 201208:00 Registration09:00 Welcome, announcements. Chairs: Dr. Joost Lötters, Prof. Gerald Urban09:15 Invited talk 1: Dr. Mirko Lehmann, IST AG, Switzerland

Different Flow Applications Require Different Devices and Technologies

Chairs: Dr. Joost Lötters, Prof. Gerald Urban

09:40 Session 1: Sensors. Chairs: Dr. Joost Lötters, Prof. Gerald Urban09:40 A01: Klaus Mathwig, Shuo Kang, Dileep Mampallil and Serge G. Lemay

Measuring Picoliter-per-Minute Flow Rates by Electrical Cross-correlation Spectroscopy

10:00 A02: Diego Reyes Romero, Ali Cubukcu and Gerald UrbanSimulation of the Oscillatory Excitation of a Thermal Flow Sensor

10:20 A03: Harmen Droogendijk and Gijs J.M. KrijnenTunable Sensors Resposne by Voltage-Control in Biomimetric Hair Flow Sensors

10:40 A04: Wouter Sparreboom, Marcel Katerberg, Theo Lammerink, Ferry Postma, Jeroen Haneveld, Jarno Groenesteijn, Remco Wiegerink and Joost LöttersCompact Mass Flow Meter Based on a Micro Coriolis Flow Sensor

11:00 Coffee Break / Poster / Exhibition

11:30 Session 2: Actuators. Chairs: Prof. Roland Zengerle, Prof. Shuichi Shoji11:30 B01: Yawar Abbas, Junichi Miwa, Roland Zengerle and Felix von

StettenDevelopment of an Active Micromixer Using an External Mechanical Actuator Array

11:50 B02: Nils Lass, Lutz Riegger, Andreas Ernst, Roland Zengerle and Peter KoltayEnhanced liquid metal micro droplet generation by pneumatic actuation based on the starjet method

9Enschede, the Netherlands

12:10 B03: Afshan Jamshaid, Masaya Igaki, Donghyun Yoon, Tetsushi Sekiguchi and Shuichi ShojiControllable Active Micro Droplets Merging Device Using Horizontal Pneumatic Valves

12:30 B04: Dong Hyun Yoon, Junichi Ito, Tetsushi Sekiguchi and Shuichi ShojiActive and Precise Control of Microdroplet Division Using Horizontal Pneumatic Valves in Bifurcating Microchannel

12:50 Lunch / Poster / Exhibition

14:00 Session 3: Fluidic Control Systems I. Chairs: Dr. W. Jouwsma, Prof. M.C. Elwenspoek14:00 C01: Laurent Tanguy, Andreas Ernst, Stefan Bammesberger, Roland

Zengerle and Peter KoltayPressure Driven and Regulated Dispenser for the Microliter Range

14:20 C02: Stefan Bammesberger, Andreas Ernst, Tanguy Laurent, Peter Koltay and Roland ZengerleA Calibration-free, Disposable, Non-contact Reagent Dosing Cartridge for the Sub-µL Range

14:40 C03: Martina Hitzbleck and Emmanuel DelamarcheAdvanced Capillary Soft Valves for Flow Control in Self-driven Microfluidics

15:00 C04: Philipp Meyer, Slim Larbi, Sydney Hakenberg, Carsten Hermann, Gregory Dame and Gerald UrbanA Fully Integrated Electrochemical Pump for Microfluidic Chip Systems

15:20 Coffee Break / Poster / Exhibition

15:45 Invited talk 2: Prof. dr. Volker Hessel, Technical University of Eindhoven, the NetherlandsFrom Microfluidics to Future Factories in Chemistry: Intensification at All Scales

Chairs: Prof. Han Gardeniers, Prof. Miko Elwenspoek

16:15 Poster Session. Chairs: Prof. Miko Elwenspoek, Prof. Shuichi Shoji

10 MFHS 2012

PostersSENSORSP01: Christoph Hepp, Florian Krogmann and Gerald Urban

Determination of Thermal Gas Properties and Flow Speed Using Thermal Flow Sensors

P02: Dong Liang, Muniyogeshbabu Thanikhatla Govindaiah, Laurent Tanguy, Andreas Ernst, Roland Zengerle and Peter Koltay Online Liquid Calibration Technologies

P03: Fred Hamlin, Andrew Gallant and Christopher ReayA Micro-thermal Flow Sensor for Shunt Blockage Detection in Patients with Hydrocephalus

P04: Peter LucasStandards for Low to Ultra-low Flow Rates for Drug Delivery Applications

P05: Remco Wiegerink, Theo Lammerink, Jarno Groenesteijn, Marcel Dijkstra and Joost Lötters Micro Coriolis Mass Flow Sensor for Chemical Micropropulsion Systems

P06: Subhajit Guha, Klaus Schmalz, Christian Wenger, Wolfgang Krautschneider and Chafik MelianiCMOS MEMS Based Microfluidic System for Cytometry at 5 GHz

ACTUATORSP07: Albert Prak, Theo Veenstra, Frederik Schreuder, Floris Falke and Guus

BorstComparison of Two Types of Hybrid Microfluidic Valves for Complex Microfluidic Flowpath Configurations

P08: Kenta Hasegawa, Dong Hyun Yoon, Asahi Nakahara, Tetsushi Sekiguchi and Shuichi ShojiStructure Controlled Polymeric Microlens Fabrication Using Multiphase Droplet Assembly

P09: Michael Suppan, Sylvia R Scheicher, Heinz Pichler, Markus Rumpler, Valentin Satzinger, Martin Hajnsek and Stefan KöstlerPassive Valve Based Microfluidic Structure for Metering

P10: Rui Sekine, Haruka Okada, Takashi Sakurai, Yoon Donghyun, Ryo Iizuka, Tetsushi Sekiguchi, Takashi Funatsu and Shuichi ShojiSimplfied Microfluidic-based System to Generate Double Emulsion Micro Droplets for Biomedical Applications

INTERFACESP11: Thomas Leneke, Marc-Peter Schmidt, Sören Hirsch and Bertram

Schmidt A Microfluidic Interposer Based on a Three Dimensional Molded Substrate Technology

11Enschede, the Netherlands

P12: Thomas Schönstein Polymer-Based Micro Flow Sensor with Alternative Electronic Signal Interfaces for Low and High Flow Rates

P13: J. Groenesteijn, M. J. De Boer, T.S.J. Lammerink, J.C. Lötters and R.J. WiegerinkWafer-through Acces Trenches for Surface Channel Technology

FLUIDIC CONTROL SYSTEMSP14: Charles-André Kieffer, Stéphane Ritty, Thomas Boudot, Nicolas Petit,

Jérémie Weber and Anne Le NelPrecise Fluid Handling System Based on Pressure Regulation

P15: Dong Liang, Laurent Tanguy, Andreas Ernst, Roland Zengerle and Peter KoltayNovel Gravimetic Calibration Method for Nano Liter Liquid Handling Devices

P16: Hunhee Kim and Junghwa HongDesign of Time Gate for Performance Improving of Lab-on-a-Chip

P17: M.S. Groen, D.M. Brouwer, J.C. Lötters and R.J. WiegerinkTowards a Microvalve for Proportional Control of Mass Flow

P18: René C.H. van der Burgt, Patrick D. Anderson and Frans N. van de VosseProbing Red Blood Cell Dynamics

P19: Stefan Bammesberger, Sabrina Kartmann, Tanguy Laurent, Dong Liang, Klaus Mutschler, Andreas Ernst, Peter Koltay and Roland ZengerleA Low-cost, Normally Closed, Solenoid Valve for Non-contact Dispensing in the Sub-µL Range

P20: Sydney Hakenberg, Matthias Hügle, Gregory Dame and Gerald UrbanA Microfluidic Passive Batch Mixing Chip for Recombinase Polymerase Amplification Utilizing Phaseguide Technology

P21: Tsung-Ju Chen, Fan-Gang Tseng and Ching-Chang ChiengFlow Stopping Using a 3D-structured Microfluidic T-junction

12 MFHS 2012

APPLICATIONSP22: Albert Mouris, Remco Wiegerink, Joost Lotters, Marco Pap and Theo

LammerinkThe Application of Micro-and Nanofluidics in Wobbe Index Meters

P23: Bas van den Broek, Pieter Nieuwland and Kaspar KochMicroreactortechnology: Real-Time Flow Measurements in Organic Synthesis

P24: Cor Rops, Giaco Oosterbaan and Cees van der GeldPressure Drop Reduction in Conical Channel Micro Evaporators

P25: Maurizio R. Gullo, Ryohei Ueno, Yuan Pang, Nobuyuki Takama, Yasuyuki Sakai, Beomjoon Kim and Jürgen BruggerTowards Single Cell Level Heat Shock Protein Expression by Means of Hydrodynamic Trapping and Local Heating

18:30 Closure of the day

19:00 Conference dinner at Hotel Restaurant Rhodenbach20:00 Evening lecture: Dr.Ir. Kees de Gooijer, Food and Nutrition Delta, the Netherlands

Microfluidic Handling Systems: Where To Apply Them? Chairs: Dr. Joost Lötters, Prof. Gerald Urban

Friday 12 October 201208:00 Registration09:00 Welcome, announcements. Chairs: Dr. Joost Lötters, Prof. Gerald Urban09:15 Invited talk 3: Dr. Tom van de Goor, Agilent Technologies, Germany

Microfluidic Components Driving Performance in Liquid Chromatography

Chairs: Dr. Joost Lötters, Prof. Gerald Urban

09:40 Session 4: Fluidic control systems II. Chairs: Dr. Wybren Jouwsma, Prof. Shuichi Shoji09:40 D01: Paul Vulto, Sebastiaan Trietsch, Jos Joore and Thomas

HankemeierPhaseguides: a Paradigm Shift in Microfluidic Liquid Handling

10:00 D02: Karin Schroen, Maartje Steegmans, Koen van Dijke, Thomas Krebs and Remko BoomNew Insights Gained from Making and Breaking emulsions in Microfluidic Devices

10:20 D03: Christopher David, Pierre Claudel and Joost LöttersWater Flow Calibration Facility in France (1 mL/h to 10 000 mL/h)

13Enschede, the Netherlands

11:40 D04: Trieu Nguyen, Yanbo Xie, Lennart J. de Vreede, Albert van Den Berg and Jan EijkelEnhanced Energy Conversion from the Streaming Potential by Polymer Addition

11:00 Coffee Break / Poster / Exhibition

11:30 Session 5: Applications. Chairs: Prof. Han Gardeniers, Prof. Roland Zengerle11:30 E01: Johannes Sackmann, Katharina Burlage, Christof Gerhardy, Dirk

Loibl, Liangyu Cui and Werner Karl SchomburgPolymer Micro Fluidic Systems Fabricated by Ultrasound

11:50 E02: Drew Owen, Wenbin Mao, Alexander Alexeev, Jenifer Cannon and Peter HeskethMicrobeads for Sampling and Mixing in a Complex Sample

12:10 E03: Yanbo Xie, Lennart J. de Vreede, Trieu Nguyen, Albert van Den Berg and Jan EijkelHigh Efficiency Energy Conversion from Liquid Jet Flow

12:30 E04: Winfred Kuipers, Michael Deilmann, Michael Gerding, Thorsten Neumann, Michael Vogt, Gregor Quiring, Regulo Miguel Ramirez Wong, Maria Reinhardt-Szyba, Henning Wehrs and Jörg MüllerRealization of a Miniaturized Mass Spectrometer Based on a Microfluidic Device

12:50 Closure of the conference, best paper / poster award, next conference

13:15 Lunch

14:30 Optional: lab tour at MESA+ / TST labs17:00 Closure

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ProgrammeWednesday 11 October 201217:00 Registration18:00 Welcome Reception19:00 Demonstration / explanation of Roulette / Black Jack21:00 Closure

Thursday 12 October 201208:00 Registration09:00 Welcome, announcements09:15 Invited talk 1: Dr. Mirko Lehmann, IST AG, Switzerland09:40 Session 1: Sensors11:00 Coffee Break / Poster / Exhibition11:30 Session 2: Actuators12:50 Lunch / Poster / Exhibition14:00 Session 3: Fluidic Control Systems I15:20 Coffee Break / Poster / Exhibition15:45 Invited talk 2: Prof. dr. Volker Hessel, Technical University of

Eindhoven, the Netherlands16:15 Poster Session18:30 Closure of the day19:00 Conference dinner, Hotel Restaurant Rodenbach20:00 Evening lecture (during dinner): Dr.Ir. Kees de Gooijer, Food and

Nutrition Delta, the Netherlands

Friday 12 October 201208:00 Registration09:00 Welcome, announcements09:15 Invited talk 3: Dr. Tom van de Goor, Agilent Technologies, Germany09:40 Session 4: Fluidic control systems II11:00 Coffee Break / Poster / Exhibition11:30 Session 5: Applications12:50 Closure of the conference, best paper / poster award, next

conference13:15 Lunch14:30 Optional: lab tour at MESA+ / TST labs17:00 Closure

For question contact: mfhs2012@utwente.nl or +31 (0)64 282 9007