Post on 02-Aug-2020
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Colja Laane Board member Regiegroep Life Sciences & Health
Director Netherlands Genomics Initiative
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10 June 2014, Amsterdam
Healthcare Innovation Day, The Netherlands - Israel
Topsector Life Sciences & Health
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Life Sciences & Health in The Netherlands
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Regiegroep Life Sciences & Health
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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written
• In 2011 the ‘Regiegroep LSH’ was formed
• In 2012 the ‘Innovation contract’ has been signed
• In 2012 ‘LSH Plaza’ became operational
• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships
Topsector LSH: were do we stand ?
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Regiegroep Life Sciences & Health
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The topsector's vision links health and wealth for society and economy
LIFE SCIENCES
& HEALTH
Society Economy
Hea
lth
W
ealt
h
QUALITY OF LIFE
PRODUCTIVITY
AFFORDABILITY BUSINESS
The topsector envisions a thriving Dutch Life Sciences & Health sector that develops innovative health solutions based on scientific excellence that:
> improve QUALITY OF LIFE of patients
> support the AFFORDABILITY of healthcare
> increase PRODUCTIVITY within and beyond healthcare
> create BUSINESS VALUE in the Netherlands
Source: topsectorplan; cahier no. IV
Vision
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Regiegroep Life Sciences & Health
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Ambition: 3 objectives, which together contribute to affordable, high-quality healthcare
PREVENTION CURE CARE
1. Maintain health, prevent healthcare
2. Maximize effect, minimize trauma
3. Manage disease extramurally
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Regiegroep Life Sciences & Health
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The topsector plan identified 7 critical success factors for a strong Life Sciences & Health sector
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IDEA GENERATION Increase the number of promising ideas
DEVELOPMENT Accelerate the development process and heighten the chance of success
APPLICATION Accelerate and broaden effective application (nationally and internationally)
Demanding Dutch market with a portal into Europe and the rest of the World
1
Optimized legal and regulatory landscape 2
Sufficient well educated, entrepreneurial people 3
Good accessibility to the right capital 4
Shared public-private innovation infrastructure 6
The Netherlands as one self-organized Life Sciences & Health sector 7
Strong, accessible (fundamental) knowledge base 5
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Regiegroep Life Sciences & Health
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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written
In 2011 the ‘Regiegroep LSH’ was formed
• In 2012 the ‘Innovation contract’ has been signed
• In 2012 ‘LSH Plaza’ became operational
• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships
Topsector LSH: were do we stand ?
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Regiegroep Life Sciences & Health
A 'Regiegroep' was installed to bundle forces in the sector and to stimulate, facilitate and integrate LSH activities
A core team has been given the mandate to act on behalf of the ‘Regiegroep’: Large industry: Rob van Leen SME’s: Hans Schikan, Len de Jong Academia: Huib Pols Government: Paul Huijts Secretariat: Frans van den Boom Petra van Baak (EZ) URL: www.regiegroepLSH.nl
Hans Schikan
Martin Paul
Huib Pols
Roger van Boxtel
Geri Bonhof EDUCATION
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Regiegroep Life Sciences & Health
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Important deliverable: Regiegroep members have started ‘own’ instruments for the LSH sector
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Regiegroep Life Sciences & Health
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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written
In 2011 the ‘Regiegroep LSH’ was formed
In 2012 the ‘Innovation contract’ has been signed
• In 2012 ‘LSH Plaza’ became operational
• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships
Topsector LSH: were do we stand after?
1
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Regiegroep Life Sciences & Health
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‘Innovation contract’: 10 roadmaps connect and structure the sector based on technology or applications area’s
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PREVENT DIAGNOSE CURE CARE
Keep people healthy as long as possible
Diagnose early, before complica-tions arise
Individua-lize treatment for best results
Treat with minimal side-effects
Replace or repair body functions
Move from care to cure (unmet needs)
Reduce symptoms, slow down disease
Enable chronic patients to stay at home
Molecular diagnostics
Imaging & image guided therapies
Pharmacotherapy
One Health
Regenerative medicine
Global health (previously neglected diseases)
Health technology assessment & quality of life
Specialized nutrition, health & disease
Enabling technologies & infrastructure
RO
AD
MA
PS
Self-management, home care & ICT
Many x-topsector initiatives
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Regiegroep Life Sciences & Health
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In 2011the topsector plan ‘voor een gezond en welvarend Nederland’ was written
In 2011 the ‘Regiegroep LSH’ was formed
In 2012 the ‘Innovation contract’ has been signed
In 2012 ‘LSH Plaza’ became operational
• From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships
Topsector LSH: were do we stand?
1
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Regiegroep Life Sciences & Health
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LSH Plaza builds upon existing expertise by bringing together stakeholders in the LSH sector
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Through its structural core, the LSH Plaza performs basic stimulus, facilitation and integration activities
according to the ambition, securing the Plaza's operation and continuation
STRUCTURAL CORE
NETWORK OF ENABLERS
Through its network of enablers, the LSH Plaza mobilizes enabling organizations to perform extended stimulus, facilitation and integration activities, and shape the
public-private innovation infrastructure
The network of enablers will be in continuous motion, as existing enablers may end and new enablers may start
The network of enablers contains different organizations with different roles and different
relations to the Plaza and its structural core
GOVERNMENT
PRIVATE
NETWORK OF ENABLERS
LSH PLAZA
PUBLIC
STRUCTURAL CORE
TTIs Industry
organizations
Health foundations
NGI
DTL/e-science center
LS@Work
Tech transfer offices
Roadmaps/ community
leaders
…
…
…
Biobanks
e.g. SMEs, large industry, health insurers, health foundations, financiers, etc.
e.g. universities, UMCs, KNAW/NWO institutes, TNO, etc.
…
NWO/ ZonMw/
STW
Syntens
Regions/ regional
initiatives
…
…
TNO
Science parks, shared
infrastructure
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Regiegroep Life Sciences & Health
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LSH Plaza has the mission to support public-private partnership in Life Sciences & Health
Mission
LSH Plaza
Basic knowledge Translation Delivery
SCIENCE PUSH MARKET PULL
PPP
Partners Experience
Investments
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Regiegroep Life Sciences & Health
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In 2011 the topsector plan ‘voor een gezond en welvarend Nederland’ was written
In 2011 the ‘Regiegroep LSH’ was formed
In 2012 the ‘Innovation contract’ has been signed
In 2012 ‘LSH Plaza’ became operational
From 2012 onwards several calls for proposals were initiated to stimulate public-private partnerships
Topsector LSH: were do we stand?
1
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Regiegroep Life Sciences & Health
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Recent calls for proposals aimed at building partnerships
>2012 IMDI (ZonMW) 2013 LSH Impuls > 2013 LSH Match
> 2013 MIT > 2012 Research Hotels 2014 2Treat (ZonMW)
2014 Memorable (ZonMW)
Building on PPPs: • NGI • Topinstitute Pharma • CTMM • BMM Total: € 400 M/y
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Regiegroep Life Sciences & Health
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• Horizon 2020 (~70 billion/7 yrs; ~12% for health) as
Common Strategic Framework
• Structural funds (EFRO, ESF)
• European Innovation Partnerships (EIP, public-private)
Europe 2020: meeting the grand challenges
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Regiegroep Life Sciences & Health
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The EU agenda has a clear connect with the LSH and other topsectors: for example in Active & Healthy Ageing
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Prevention,
Awareness,
Screening, Early
diagnosis
Cure & Care Active Ageing,
Independent
living
Creative
industry
Life
Science &
Health
Hightech
Systems &
Materials
Agro/food
Molecular diagnostics,
Imaging & image guided
interventions
Regenerative medicine
Health Economics
--------------- Media & ICT, Serious gaming, Smart Design ----------------
Pharmacology and
pharmacotherapy,
Regenerative medicine
ICT & clinical decision
support,
Hospital-to-home care
Imaging & image guided
interventions
ICT & clinical decision
support,
Self management
Hospital-to-home care
Cardiovascular health,
Gastro intestinal health,
Food and cognition
Weight management,,
Food and cognition,
Sensory & liking
Weight management,
Food, ageing & cognition
Medical imaging,
Patient specific modelling,
New modalities for diagnostics,
Image-Guided interventions,
Neurostimulation,
Micro- and nanotechnology,
Minimal invasive techniques,
Neurostimulation,
Micro- and nanotechnology,
Biomaterials
Rehabilitation techniques
Rehabilitation techniques
Home and community care
Mechatronics & robotics
Home and nomadic monitoring,
EIP AHA pillars
Topsectors
Connect with the
EIP-AHA constituents:
- Joint programming:
ERANET’s, JPI’s,
Art 185
- Joint infrastructures:
ESFRI’s
EIP- AHA pillars
Du
tch
top
sect
ors
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Regiegroep Life Sciences & Health
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LSH hot spots
Gelderland and Overijssel: Health Valley, and Twente
• Focus on: Cognitive neuro-sciences, molecular diagnostic, Nanotechnology, technical medical science, care and cure robotica, eHealth
• Important players: NXP Synthon, TNO, Siemens, Astellas, TU Twente, RUN, UMC St Radboud
Zuid-Limburg: Brainport
• Focus on: CV-diseases, metabolic aspects of chronical diseases, public health & primary care, mental healthcare and neuro-sciences. Medical devices
• Important players: DSM, Chemelot, UMC Health Campus,
Noord-Nederland: HANNN
• Focus on: Healthy Ageing • Important players: PRA International, RUG, UMCG,
Hanzehogeschool, Zernike Science Park, ERIBA (and collaboration with Wageningen)
Amsterdam Biomed Cluster
• Focus on: Oncology, cognitive neuro-sciences and neuroimaging, cardiovascular, infectious diseases
• Important players: AMT, VU, VUMC, UvA, AMC, NIN, NKI
Noord-Brabant: Brainport
• Focus on: Medical technology, farmacy, veterinary health and feed
• Important players: Philips Healthcare, MSD/ Organon, MSD/Intervet, GE Healthcare, TU Eindhoven, Amgen
Utrecht and Wageningen: Utrecht Life Sciences & Immuno Valley
• Focus on: Public health, oncology, 'regenerative medicine', stamcells, veterinary diseases, functional foods
• Important players: Genmab, GSK, Danone, UU, UMC Utrecht, RIVM, WuR, TNO
Zuid-Holland: Medical Delta
• Focus on: (Bio)farma, clinical research, 'imaging and image guided medicine' en 'targeted molecular technology'
• Important players: Crucell, Galapagos, Prosensa, Octoplus, J&J/Janssen Biologics, University Leiden, LUMC, TU Delft, Erasmus Medical Centre,
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Regiegroep Life Sciences & Health
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Future steps
• Build and intensify relations with research funders
• Develop and implement a shared agenda (e.g. Nederland in Zicht)
• Invest in building EU LSH consortia
• Develop cross over initiatives with other topsectors
• Develop consortia who take ownership of roadmaps building up
already existing strenghts and networks
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More information: www.regiegroeplsh.nl www.lshplaza.nl