Post on 18-Feb-2018
7/23/2019 Solutions Used in OMFS-NAGARAJ TANNERU
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Carnoy's Solution is a fixative composed of 60% ethanol, 30% chloroform and 10%
glacial acetic acid.
In Oral and Maxillofacial Pathology: A Rationale for Diagnosis and Treatment [2], theauthors state that arno!"s #olution is composed of$
• 1 g of erric hloride &el3' dissolved in 2( m) of a*solute
alcohol
• 12 m) of chloroform
• ( m) of glacial acetic acid
+his is the same proportion *! volume as the previous formula, ith the addition of
erric hloride.
Uses
#ome of the uses of arno!"s solution are$
• -nhancing l!mph node detection during dissection of cadavers.[3]
• Immunohistochemical fixation and detection of / receptors ithin the
murine hippocampus.[(]
• pplied directl! folloing enucleation for the treatment of eratoc!stic
odontogenic tumors.
• In some cases direct application folloing enucleation for certain inds of
unic!stic amelo*lastoma.[] +his appears to decrease the lielihood of recurrence
over enucleation alone.
[4]
5rotein coagulation is thought to limit uptae of thesetoxic materials *! surrounding tissues, hoever it is this fact that limits its
usefulness as a treatment agent in general.[2]
• s a fixative for pap smear samples.[10]
• s a fixative agent for *oth nuclear and mitochondrial in various tissues.[11]
• s a fixative agent to preserve mucus, useful for tissue preparation *efore staining
ith periodic acid#chiff *ase.[12]