7/23/2019 Solutions Used in OMFS-NAGARAJ TANNERU

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Carnoy's Solution is a fixative composed of 60% ethanol, 30% chloroform and 10%

glacial acetic acid.

In Oral and Maxillofacial Pathology: A Rationale for Diagnosis and Treatment [2], theauthors state that arno!"s #olution is composed of$

• 1 g of erric hloride &el3' dissolved in 2( m) of a*solute

alcohol

• 12 m) of chloroform

• ( m) of glacial acetic acid

+his is the same proportion *! volume as the previous formula, ith the addition of

erric hloride.

Uses

#ome of the uses of arno!"s solution are$

• -nhancing l!mph node detection during dissection of cadavers.[3]

• Immunohistochemical fixation and detection of / receptors ithin the

murine hippocampus.[(]

• pplied directl! folloing enucleation for the treatment of eratoc!stic

odontogenic tumors.

• In some cases direct application folloing enucleation for certain inds of

unic!stic amelo*lastoma.[] +his appears to decrease the lielihood of recurrence

over enucleation alone.

[4]

 5rotein coagulation is thought to limit uptae of thesetoxic materials *! surrounding tissues, hoever it is this fact that limits its

usefulness as a treatment agent in general.[2]

• s a fixative for pap smear  samples.[10]

• s a fixative agent for *oth nuclear and mitochondrial in various tissues.[11]

• s a fixative agent to preserve mucus, useful for tissue preparation *efore staining

ith periodic acid#chiff *ase.[12]