PRODUCT PHASE DESCRIPTION PORESIZE*(nm)

PARTICLESIZE*(µm spherical)

CARBONLOAD**(%C)

pH TYPICAL APPLICATIONS

Reve

rsed

Pha

se

C18

YMC-Triart Prep C18-S pH-stable organic/inorganic hybrid particle, polymeric bonding 12; (20) 10; 15; 20 20 2.0–10.0 first choice for method development, most versatile phase

YMC*Gel ODS-A-HG one of YMC's international bestsellers, traditional high performance C18 silica 8; 12; 20; 30 10; 15; 20; 50 20; 17; 12; 7 2.0–7.5 pharmaceuticals, vitamins, peptides, amino acids, general purpose phase

YMC*Gel ODS-AQ-HG "hydrophilic" endcapping, for 100% aqueous eluent systems 8; 12; 20 10; 15; 20; 50 15; 14; 10 2.0–7.5 strong polar compounds, pharmaceuticals, peptides, nucleic and amino acids

C8

YMC-Triart Prep C8-S pH-stable organic/inorganic hybrid particle, polymeric bonding 12; 20 10; 15; 20 13 2.0–10.0 proteins and peptides, general purpose phase

YMC*Gel C8-HG (Octyl) traditional C8, high coverage monomeric bonding chemistry 12; 20; 30 10; 15; 20; 50 10; 7; 4 2.0–7.5 proteins and peptides, estrogens, general purpose phase

YMCbasic specifically designed for the separation of basic compounds and peptides 20 10 7 2.0–7.5 basic molecules w/o modifiers, peptides

YMC*Gel Ph-HG (Phenyl) monomeric bonded phenyl using π electron interactions 12; (20; 30) 10; 15; 20; 50 9 2.0–7.5 phenols, fullerenes, sweeteners, aromatics

C4 YMC*Gel C4-HG (Butyl) traditional C4, less hydrophobic surface structure than C8 packing material 12; 20; 30 10; 15; 20; 50 7; 5; 3 2.0–7.5 biological separations, polar compounds, proteins

C1 YMC*Gel TMS-HG trimethylsilane bonding, excellent hydrolytic stability 12; (20; 30) 10; 15; 20; 50 4 2.0–7.5 water-soluble vitamins

YMC Omega specifically designed for the separation of polyunsaturated fatty acids proprietary 10; 20; 50 15 2.0–7.5 polyunsaturated fatty acids, EPA, DHA

Nor

mal

Pha

se/H

ILIC YMC*Gel NH2-HG (Amino) primary amino derivative, high coverage monomeric bonding chemistry 12; (20; 30) 10; 15; 20; 50 3 2.0–7.5 saccharides, nucleotides, water-soluble vitamins

YMC*Gel CN-HG (Cyano) for RP and NP applications, useful also for SFC and HILIC 12; (20; 30) 10; 15; 20; 50 7 2.0–7.5 proteins, steroids, catechols, for SFC applications

YMC*Gel Diol-HG for NP applications, high recovery for biological material, suitable for HILIC and SFC 12; 20; 30 10; 15; 20; 50 – 2.0–7.5 polar natural products, pharmaceuticals, for HILIC and SFC applications

YMC*Gel SIL-HG (Silica) ultra high purity, high mechanical stability, suitable for HILIC and SFC 6; 8; 12; 20; 30 10; 15; 20; 50 – – small organic molecules, fat-soluble vitamins, tocopherols, steroids

YMC*Gel SIL (Silica) high purity, suitable for MPLC and column chromatography 6; 12 50; 75; 150 – – small organic molecules, fat-soluble vitamins, tocopherols, steroids

IEX

BioPro IEX Q75 high dynamic binding capacity, hydrophilic polymer anion exchange media porous 75 – 2.0–12.0 monoclonal antibodies, proteins and peptides, IgG

BioPro IEX S75 high dynamic binding capacity, hydrophilic polymer cation exchange media porous 75 – 2.0–12.0 monoclonal antibodies, proteins and peptides, IgG

BioPro IEX SmartSep Q10/20/30 high mechanical strength, hydrophilic polymer anion exchange media porous 10; 20; 30 – 2.0–12.0 oligonucleotides, antibody pharmaceuticals, proteins and peptides

BioPro IEX SmartSep S10/20/30 high mechanical strength, hydrophilic polymer cation exchange media porous 10; 20; 30 – 2.0–12.0 antibody pharmaceuticals, proteins and peptides, insulin

SEC

YMC*Gel Diol-HG-120 versatile phase for gel filtration separations for MW 5,000 to 100,000 Da 12 10; 15; 20; 50 – 5.0–7.5 intermediate proteins, oligosaccharides

YMC*Gel Diol-HG-200 versatile phase for gel filtration separations for MW 5,000 to 300,000 Da 20 10; 15; 20 – 5.0–7.5 large proteins, polysaccharides

YMC*Gel Diol-HG-300 versatile phase for gel filtration separations for MW 20,000 to 1,000,000 Da 30 10; 15; 20 – 5.0–7.5 very large proteins, antibodies, polysaccharides

Chir

al

Po

lysa

ccha

rid

es

CHIRAL ART Amylose-C coated derivative [alternative to CHIRALPAK® AD] proprietary 10; 20 – – wide application range, SFC/SMB

CHIRAL ART Amylose-C Neo extended resolution and loadability, coated [alternative to CHIRALPAK® AD] proprietary 10; 20 – – wide application range, SFC/SMB

CHIRAL ART Cellulose-C coated derivative [alternative to CHIRALCEL® OD] proprietary 10; 20 – – wide application range, SFC/SMB

CHIRAL ART Amylose-SA immobilised derivative [alternative to CHIRALPAK® IA] proprietary 10; 20 – 2.0–9.0 wide application range for RP, NP, SFC and SMB

CHIRAL ART Cellulose-SB immobilised derivative [alternative to CHIRALPAK® IB] proprietary 10; 20 – 2.0–9.0 wide application range for RP, NP, SFC and SMB

CHIRAL ART Cellulose-SC immobilised derivative [alternative to CHIRALPAK® IC] proprietary 10; 20 – 2.0–9.0 wide application range for RP, NP, SFC and SMB

CHIRAL ART Cellulose-SJ immobilised derivative [alternative to coated CHIRALCEL® OJ] proprietary 10; 20 – 2.0–9.0 wide application range for RP, NP, SFC and SMB

Chiral Prep CD ST cyclodextrin based stationary phase for chiral RP separations 12 10; 20; 50 – 2.0–7.0 chiral separations, structural isomers

Chiral Prep CD PM phenyl modified cyclodextrin based phase, for NP and RP applications 12 10; 20; 50 – 2.0–7.0 chiral separations, structural isomers

Bulk Packing Material for Preparative Chromatography

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Europe GmbH · Schöttmannshof 19 · D-46539 Dinslaken · Phone +49 (0) 2064 427-0 · Fax +49 (0) 2064 427-222 · Email: info@ymc.de · www.ymc.de

Bulk Packing Material for Preparative Chromatography

YMC*Gel Diol-HG 120

MW < 5,000

MW 5,000 ~ 100,000

MW 5,000 - 100,000 Da

MW 5,000 - 300,000 Da

MW 20,000 - 1,000,000 Da

YMC-Triart Prep series, YMC*Gel series

YMC*Gel series wide pore materials, YMCbasic

Reversed Phase

Size Exclusion (SEC)

Ion Exchange (IEX)

strong cation exchanger

strong anion exchanger

BioPro IEX S75 / BioPro IEX SmartSep S10/20/30

BioPro IEX Q75 / BioPro IEX SmartSep Q10/20/30

YMC*Gel Diol-HG 200

YMC*Gel Diol-HG 300

Proteins / Peptides

Ion Exchange (IEX)

strong cation exchanger

strong anion exchanger

BioPro IEX S75 / BioPro IEX SmartSep S10/20/30

BioPro IEX Q75 / BioPro IEX SmartSep Q10/20/30

MW 5,000 - 100,000 Da

MW 5,000 - 300,000 Da

MW 20,000 - 1,000,000 Da

Size Exclusion (SEC)

Reversed PhaseYMC*Gel Diol-HG 120

YMC*Gel Diol-HG 200

YMC*Gel Diol-HG 300

(Monoclonal) Antibodies

Reversed Phase

Ion Exchange (IEX)

strong cation exchanger

strong anion exchanger

BioPro IEX S75 / BioPro IEX SmartSep S10/20/30

BioPro IEX Q75 / BioPro IEX SmartSep Q10/20/30

YMC-Triart Prep series, YMC*Gel ODS-AQ-HG

YMC-Triart Prep series, YMC*Gel series

Oligonucleotides / Nucleic Acids

Nucleic acid bases, nucleosides, nucleotides

Oligonucleotides

Small Molecules

polar

hydrophobic

YMC-Triart Prep C18-S, YMC*Gel ODS-AQ-HG

YMC-Triart Prep series,YMC*Gel series

CH3

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