BioTRANSformation of by-products from fruit and vegetable processing industry into valuable
BIOproducts
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
BRUNO SOMMER FERREIRACEO – BIOTREND SA
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 0
Presentation outline
- Industrial Biotechnology
- Bio-based economy
- Feedstock
- Beyond 1st generation
- Biorefinery concept
- Examples
- About Biotrend
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 1
Industrial biotechnology
Food additives
BiopolymersRenewableresources
Micro-organisms
IndustrialBiotechnology
Fuels & Chemicals
And more, much more…
A plethora of products:
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 2
Industrial biotechnology
Starch
Lignin
Oil
Protein
Biomass Feedstocks
Intermediate Platforms
Building Blocks
Products/Uses
Biobased Syn Gas
Sugars Glucose Fructose Xylose Arabinose Lactose Sucrose Starch
Ethanol Glycerol Lactic acid Succinic acid Fumaric acid Propionic acid Malic acid Furfural Aspartic acid Glucaric acid Glutamic acid Itaconic acid Levulinic acid Malic acid Hydroxy propionic acid Sorbitol Xylitol Arabinitol
Textiles Carpets, Fibers, fabrics, fabric coatings, foam cushions, upholstery, drapes, lycra, spandex
Safe Food Supply Food packaging, preservatives, fertilizers, pesticides, beverage bottles, appliances, beverage can coatings, vitamins
Transportation Fuels, oxygenates, anti-freeze, wiper fluids molded plastics, car seats, belts hoses, bumpers, corrosion inhibitors
Housing Paints, resins, siding, insulation, cements, coatings, varnishes, flame retardents, adhesives, carpeting
Recreation Footgear, protective equipment, camera and film, bicycle parts & tires, wet suits, CD’s, DVD’s, golf equipment, camping gear, boats
Health and Hygiene Plastic eyeglasses, cosmetics, detergents, pharmaceuticals, suntan lotion, medical-dental products, disinfectants, aspirin
Environment Water chemicals, flocculants, chelators, cleaners and detergents
Communication Molded plastics, computer casings, optical fiber coatings, liquid crystal displays, pens, pencils, inks, dyes, paper products
Industrial Corrosion inhibitors, dust control, boiler water treatment, gas purification, emission abatement, specialty lubricants, hoses, seals
Sec chemicals
Intermediates
Cellulose
Hemicellulose
Olefins Diacids Esters Dilactide Acrylate PDO BDO Furane THF Caprolactam Carnitine Phenolics
Methanol
Ether
Direct polymers
Fuel additives Solvents Emulsifiers Polymers Resins
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 3
Industrial biotechnology
0
1
2
3
4
1983 1986 1989 1992 1995 1998 2001 2004 2007 2010 2013*
Sugar Wheat Corn Soybean oil Palm oil Crude oil
Drivers for adoption
- Reduce dependence on oil-derived raw-materials;
- Use renewable resources;
- Reduce use of water
- Lower energy consumption and CO2 emissions.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 4
Industrial biotechnology
Drivers for adoption
Balance between use and generation of carbon-rich resources
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 5
Bio-based economy
World chemicals market, excluding pharma: 3000 billion USD/yearBio-based share of chemicals market (USDA, 2008)
R&D expenditures vs. future markets (OECD, 2009)
!!
0%
10%
20%
30%
2005 2010 2025
Biobased Share
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 6
Bio-based economy
Global renewable chemicals and materials market to be approximately $2.5 billion (~1.2 million metric tons) in 2012, excluding oleochemicals
Price: ~$2/kg mostly high-volume, low value products (mainly biofuels)
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 7
Bio-based economy
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 8
Bio-based economy
,814
,927
1,019
Bio-basedbulkchemicals
Other bulkchemicals
2017
1.132
113
2012
960
342007
826
12
CAGR(2012-17F)
27.5%
€ B
1.9%
Bulk chem icals m arket Specialty chem icals m arket
€ B
CAGR(2012-17F)
17.5%
4.5%
,494
,622
,776
2012
692
70
Bio-basedspecialtychemicals
Otherspecialtychemicals
2017
934
157
2007
521
26
Source: G. Festel (EFIB 2009, OECD 2010)
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 9
Bio-based economy
Sources: Research and Markets, 2013; Transparency Research, 2013
Specialty Area CAGR (%)
Biopolymers 14.3
Synthetic lubricants 2.5
Bioplastics 24.3
Biosurfactants 3.5
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 10
Bio-based economy
20
Substitutes • PLA, starch‐ based plastics
“Drop‐in” Replacements • PE, PP, PET, solvents, polymers
Improvements • Spider silk, living materials
Butanol
Adipic acid Isoprene
Succinic acid
Terephthalic acid Butadiene
BDO
PDO
Acrylic acid
Furans
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 11
Bio-based economy
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 12
Feedstock
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 13
Beyond 1st generation
Many sources are underutilized:Wood, agro-waste, manure, household waste, wastewater sludge, industrial waste.
Challenge:transform complex andheterogeneous materialsinto usable industrialraw materials.
€ 0-50/ton
> €400/ton
€0-50/ton
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 14
13
First generation feedstocks • Corn, cane, vegetable oils
Cellulosic materials • Bagasse, corn stover, woody biomass
Waste feedstocks • MSW, CO2, flue gas
Pro: commercially available, existing supply chains today, easy to convert Con: competes with food; price volatility
Pro: low cost; sometimes collected/aggregated; doesn’t compete with food Con: difficult to release sugars; high capital cost conversion; often left in field
Pro: negative cost today; doesn’t compete with food or agriculture; available near fuel demand Con: heterogeneous; costs likely rising; impurities; difficult to convert
Beyond 1st generation
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 15
Beyond 1st generation
17.5%75% RESIDUES LEFT ON FIELD
5% HUSBANDRY2.5% POWER
914 million tons of residues will be availablein eight selected regions
2030 figuresagriculturalresidues only
Source: Bloom berg New Energy Finance, “Moving towards a next -generat ion ethanol economy” 2012
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 16
Biorefinery concept
fuel
Source: Arlan Peters, WCIB 2014, Philadelphia.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 17
Potential raw-materials
Lignocellulosic residues- agriculture- forestry
Cheese whey
Glycerol- by-product of biodiesel
Wastewater sludge
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 18
Transbio’s contribution
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 19
Lignocellulosic residues for PHA
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 20
Lignocellulosic residues for PLA
Polymeriza on Fermenta on
Con nuous opera on is possible. The monomer is a erwards polymerized into PLA.
Cell‐free stream towards lac c acid
purifica on Lignocellulosic hydrolysate
sugars
Cell recycle
Micro or ultra‐filtra on membrane
Frac ona on Photosynthesis
Free carbon (CO2)
Plant biomass
Sugar frac on
Purifica on
Fermenta on broth
Bio‐based monomer Biopolymer
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 21
Lignocellulosic residues for PLA
Source; Hans van der Pol, WCIB 2014,
Philadelphia
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 22
Lignocellulosic residues for PE
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 23
Cheese whey
Regional market dynamics matters.Whey was a huge problem in Europe a decade ago. Today there is shortage of whey.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 24
Crude glycerol
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 25
Wastewater sludge
- Food waste- Olive and palm oil mills effluents- Diary effluent- Paper mill effluents- Fruit and tomato cannery effluents- Brewery effluent- Municipal wastewaters
Open, mixed cultures.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 26
Development - Building blocks
Source: Bonaire Le,July 10, 2014(Nexant Blogs)
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 27
Building blocks
Source: Babette Petersen, WCIB 2014, Philadelphia.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 28
Integration
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 29
Biotrend
Bioprocesses for a sustainable and profitable industry
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 30
Highly qualified and experienced team• Staff with international experience
(Portugal, The Netherlands, Canada, France, Germany, Switzerland)
State‐of‐the‐art facilities• Process development, optimization, integration• Process scale-up, de-risking and validation
(2-250L and beyond)
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 31
Biotrend
Example projects for clients
Large pulp and paper company, world leader in premium office paper:Fermentation-based valorization of carbon-rich liquid waste streams from pulp and paper mills.
Leading confectionery multinational and leading plastics research institute:Deconstruction and transformation of carbohydrate-rich solid residues into materials suitable for packaging applications.
Innovative enzyme engineering company: Increase the productivity and reduce the cost of the production of the enzyme.
Marine biotech start-up: Increase the yield and productivity of the production of cell extracts with cosmetic use.
Beverage company: Increase the robustness and scale-up of the production of an innovative fermented beverage.
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 32
• Ex. Marine bacteria extract production
Process intensification Improve the economics of the process
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Clients: from small start‐ups to multi‐billion USD multinationals
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 33
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Process intensification Improve the economics of the process• Ex. Industrial enzyme production
Clients: from small start‐ups to multi‐billion USD multinationals
€1300 /AU
€200 /AU
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 34
Biotrend
Collaborative R&D
At the forefront of scientific development• 7 EU co-funded large collaborative projects with partners across the industrial
biotechnology value chain (~3 million USD)• 49 companies
• 29 universities and RTDs
• 25 countries, 3 continents
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 35
Biotrend
Contacts:
Bruno Sommer Ferreira+351 231 410 [email protected]
This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no 289603
Vitoria-Gasteiz, 03-11-2015Biotrend SA Slide 36
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