Role of Ayurvedic Products in livestock Health and production- A Global Scenario

Dr (Capt) Tanweer AlamDr (Capt) Tanweer Alam

Natural Remedies, IndiaNatural Remedies, India

The comparison of scope!

Source: FAOSTAT website

Total world population Poultry : 19 BillionCattle : 1.5 billionSheep and goat : 1.6 billion

Total world population Human: 6.88 Billion

The Market

Source: FAOSTAT website & CLFMA REPORT 2009

1.5 Billion USD

Total Global Herbal Market 100 Billion USD

Total Animal Health

Herbal Market

Positive Trend: Across the Segment and Species

Digestive

Respiratory Dermal

Nutrient replacer Stress care

Global Trend of herbal products usage in Animal Health Care

Growth PromotersGrowth Promoters Global Feed additive market to grow to $18 billion by

2014 Largest contributor is the antibiotic / anti bacterial (28%)

and fastest growing is amino acid segment (6%) Herbal/ Phytoconstituents based products market is

catching up in an impressive manner (20% CAGR)

Foodceo.com

Growing Popularity : The ReasonsGrowing Popularity : The Reasons

Total number of research papers listed on PubMed containing the word "phytoconstituents."

Growing Credentials:Technical back up available

Growing Credentials:Array of Herbal Monographs

Publication and availability of authoritative monographs by various organizations, improving the scientific credibility of herbs.

Indian HerbalPharmacopoeia

British Herbal Pharmacopoeia

English Translation of

German Commissions

E monographs

American Herbal Pharmacopoeia

( AHP )

World Health Organization

(WHO)

Europe Scientific Cooperative

on Phytotherapy (ESCOP)

United States Pharmacopoeia

( USP )

Confluence of Herbal

Pharmacopoeia

Comparatively Less Gestation time of phytodiscovery

Growing Credentials:Positive Economics

Pharmaceutical Research and Development (R & D) Process

DefinitionsIND = Investigational New Drug Application FDA = U.S. Food and Drug Administration NDA = New Drug Application Source: www.Innovation.org

Growing Importance

Out of 252 drugs considered basic and essential by WHO , 11% are exclusively from plant origin and 28% are of synthetic origin but obtained from natural precursors

Eighty Five percent (85%) people in deve- loping Countries still rely on traditional medicines as first choice for human health care (WHO).

Advantage India

One of the largest flora bio diversity 75% of the medicinal plants grow naturally in

India. Good Reservoir of animal species for

reconfirming the results and ROI

Example of applications:

Role of herbs in treating skin diseases

Many results indicate that the concentration of fibers and enzymes (directly/indirectly involved in wound healing) are modulated in treated cases and promoted the wound healing.

Ocimum sanctum, Cymbopogon citratus and Andropogon nardus

Shishodia & Pande, 2000

Skin disorders and Ayurvedic Skin disorders and Ayurvedic medicinesmedicines

Pinus longifollia, Eucalyptus spp. and Cedrus deodara

Shishodia & Pande, 2000

8.40

9.90

7.5

8

8.5

9

9.5

10

Treated Untreated Control

Disappearance of lochia (Days)

100

80

0

20

40

60

80

100

Treated Untreated Control

Animals expelling placenta within 8 hrs. (%)

Adhatoda vasica & others

Example of applications:

Role of herbs in post parturient disorders

Example of applications:

Role of herbs as a Performance Enhancer

1. Andrographis paniculata

 Part Used: Whole plant

Active principle: Andrographolide

Structure:

CH3 CH2OHH

CH3

O

OOH

CH2

OH

Molecular Form ula = C 20 H 30 O 5

Form ula W eight = 350.449 Andrographolide

2. Phyllanthus amarus

Part Used: Whole plant

Marker constituents: Phyllanthin &

Hypophyllanthin

OCH3

H

OCH3

HH3CO

H3CO

OCH3

OCH3

Molecular Form ula = C 24 H 34 O 6

Form ula W eight = 418.523 Phyllanthin

O

O

H3CO

OCH3

OCH3

OCH3

OCH3

H

H H

M olecular Form ula = C 24 H 30 O 7

Form ula W eight = 430.491 Hypophyllanthin

1608

1771

1500

1550

1600

1650

1700

1750

1800

CONTROL TREATED

[a] Average body weight(gms)2.082

1.998

1.94

1.96

1.98

2

2.02

2.04

2.06

2.08

2.1

CONTROL TREATED

[b] Average F.C.R.

Example of applications:

Role of herbs as a Mycotoxin binder

1142931

1005

0

200

400

600

800

1000

1200

CTL. CTL.+CHLG. CTL.+CHLG.+TRTD.

[a] Body Weight (g.)

1.9 2.08 2.03

0.00

0.50

1.00

1.50

2.00

2.50

CTL. CTL.+CHLG. CTL.+CHLG.+TRTD.

[b] Feed Conversion Ratio

Hepatoprotection against Mycotoxins

Hepatoprotection against Mycotoxins

AfB1 0.5 ppm

(A)AfB1 0.5 ppm

+ Phyto-constituents

(B)

Conclusion

More acceptance of herbal formulation demands more validation and standarization preparedness

Educating and training the stake holders ( researchers, practitioners etc )

Exposing ethno veterinary ,to some extent ,in veterinary course curriculum

Discussion

tanweer@naturalremedy.com