Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
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Pathologic anatomy(introductory lecture)
September 16, 2007
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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Pathologic anatomy
I Institute of pathologyI medical practice (biopsy, autopsies)I teachingI research
I Department of pathology in smaller hospitals(medical practice)
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Pathology, morphology
Deals with morphologic characteristics of diseases.According to morphologic features pathologists classifyand define diagnostic units (diseases).Other methods and features are used to classify thediseases today: microbiology, immunohistology,molecular genetics. . . ).The ultimate goal of classifications is to definediagnostics units according to reliable criteria. Thisclassifications must correlate with clinical features of thedisease (prognosis, reaction to therapy. . . ).
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
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1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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General and organ pathologyI General pathologyI Organ pathology
Deals with diseases and their progress in different organsystems
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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General and organ pathologyI General pathologyI Organ pathology
Studies individual organs or organ systems and theirdiseases
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
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Pathology and its position in medicineI standalone scientific disciplineI part of clinical medicine
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
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1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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Pathology and its position in medicineI standalone scientific disciplineI part of clinical medicine
I autopsy verifies correctness of diagnosis and therapyI biopsy necessary to make a diagnosis, progress and
extent of a disease and sometimes to verify thetherapy
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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Recommended literature
I BooksI Basic Pathology (Kumar, Cotran, Robbins)I General and Systematic Pathology (Underwood)I Pathology, Basic and Systemic (Woolf)
I InternetI Hypertext atlas of pathology (in Czech)I Hypertext atlas of dermatopathologyI Hypertext atlas of fetopathology
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
Autopsy
Institutes of Pathology in Brno
I till 1962: Institute of Pathology, St. Anna HospitalI 1981 – 1983: bioptic department of MOÚI 1992 – 1995: bioptic department in BohuiceI 1994: private pathology Biocyt
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
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Methods ofpathology
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Institutes of Pathology in Brno
I till 1962: Institute of Pathology, St. Anna HospitalI 1981 – 1983: bioptic department of MOÚI 1992 – 1995: bioptic department in BohuiceI 1994: private pathology Biocyt
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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Institutes of Pathology in Brno
I till 1962: Institute of Pathology, St. Anna HospitalI 1981 – 1983: bioptic department of MOÚI 1992 – 1995: bioptic department in BohuiceI 1994: private pathology Biocyt
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
Autopsy
Institutes of Pathology in Brno
I till 1962: Institute of Pathology, St. Anna HospitalI 1981 – 1983: bioptic department of MOÚI 1992 – 1995: bioptic department in BohuiceI 1994: private pathology Biocyt
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
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Methods ofpathology
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1st institute of pathology
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
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Institutes ofPathology in Brno
1st institute ofpathology
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
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1st institute ofpathology
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Methods ofpathology
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
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Methods ofpathology
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
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Methods ofpathology
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
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2nd institute ofpathology
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Methods ofpathology
Autopsy
(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
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Methods ofpathology
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(2nd) Institute of pathology Brno
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
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prof. Sternberg
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
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prof. Neumann
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
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prof. Švejda
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
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1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
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prof. Dluhoš
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
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Methods ofpathology
Autopsy
Examinations performed by pathologists
I AutopsyI Biopsy (surgical pathology)
I pathological (medical reasons)I forensic
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Examinations performed by pathologists
I AutopsyI Biopsy (surgical pathology)
I Biopsy (tissues)I CytologyI Special methods of genetic analysis
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
The course of the autopsyI External examination of a bodyI Organ removalI Autopsy of the organs, description, taking samplesI Putting the organs back, preparation for funeralI Administrative tasks; autopsy protocol
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
The course of the autopsyI External examination of a bodyI Organ removalI Autopsy of the organs, description, taking samplesI Putting the organs back, preparation for funeralI Administrative tasks; autopsy protocol
Performed by laboratory assistent. Organ complexes areremoved from the body. It is important not to damage thebody over the necessary minimum; sections can becovered by clothes.
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
The course of the autopsyI External examination of a bodyI Organ removalI Autopsy of the organs, description, taking samplesI Putting the organs back, preparation for funeralI Administrative tasks; autopsy protocol
Autopsy of the organs is usually performed by standardmethod. Parts of dissected organs are opened in thesame way, which enables to compare the findings.Specimens of tissues are taken for microscopicexamination and other specimens are taken formicrobiology and other methods.
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
The course of the autopsyI External examination of a bodyI Organ removalI Autopsy of the organs, description, taking samplesI Putting the organs back, preparation for funeralI Administrative tasks; autopsy protocol
The body is prepared for the funeral.
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
The course of the autopsyI External examination of a bodyI Organ removalI Autopsy of the organs, description, taking samplesI Putting the organs back, preparation for funeralI Administrative tasks; autopsy protocol
Autopsy protocol is put together by pathologist after theautopsy is performed and results of other examinationsare available.
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Cooling boxes
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Autopsy protocolI Description of the autopsy and macroscopic changes
I Evaluation of histological findings and results of otherexaminations
I Diagnostic conclusionI Epicrisis (concise)I Correlation of the clinical and pathological findings
External changes, organ changes, organ weights
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Autopsy protocolI Description of the autopsy and macroscopic changes
I Evaluation of histological findings and results of otherexaminations
I Diagnostic conclusionI Epicrisis (concise)I Correlation of the clinical and pathological findings
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Autopsy protocolI Description of the autopsy and macroscopic changes
I Evaluation of histological findings and results of otherexaminations
I Diagnostic conclusionI Epicrisis (concise)I Correlation of the clinical and pathological findings
1. Basic disease (morbus principalis)2. Complications (complicationes)3. Cause of death (causa mortis)4. Accessory findings (inventu accessorii)
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Autopsy protocolI Description of the autopsy and macroscopic changes
I Evaluation of histological findings and results of otherexaminations
I Diagnostic conclusionI Epicrisis (concise)I Correlation of the clinical and pathological findings
In one or two sentences to summarize the basic disease,its course and the cause of death.
Patologic anatomy
Pathologicanatomy
Morphologicpathology
General and organpathology
Pathology and itsposition inmedicine
Recommendedliterature
Institutes ofPathology in Brno
1st institute ofpathology
2nd institute ofpathology
Historie
Methods ofpathology
Autopsy
Autopsy protocolI Description of the autopsy and macroscopic changes
I Evaluation of histological findings and results of otherexaminations
I Diagnostic conclusionI Epicrisis (concise)I Correlation of the clinical and pathological findings
1. full correlation of clinical and autoptic findings2. small differences3. substantial differences, when the clinical diagnosis is
incomplete or partially wrong and such incorrectdiagnosis influenced the therapy
4. complete discrepancy between the clinical andautoptical finding
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