Introduction of Pathologic Anatomy (Uht) 25 Mei 2011
Transcript of Introduction of Pathologic Anatomy (Uht) 25 Mei 2011
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JUDYA SUKMANA, Dr.,MKes
INTRODUCTION OF ANATOMY
PATHOLOGY
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DOSEN & STAF BAGIAN PATOLOGI ANATOMI
FK UHT
KABAG : JUDYA SUKMANA,dr.,M.Kes
SEKBAG : DUTI S AZIZ,dr.,SpPA
DOSEN :
1. EDWARD SIMON,dr.,SpPA2. SRI PINUDJI,dr.,SpPA
3. EVA P.,dr
STAF :
1. MUNIR S
2. EKO
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PATOLOGI
Patologi : Pathos (penyakit) dan Logos (ilmu)
Patologi merupakan disiplin ilmu yangmenghubungkan ilmu kedokteran dasar danklinis, mempelajari proses suatu penyakit,mempelajari perubahan struktur dan
fungsional sel, jaringan dan organ yangmendasari suatu penyakit
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Patologi :
General Pathology: mempelajari reaksi dasar yang
terjadi pada sel dan jaringan terhadap stimulusabnormal yang mendasari penyakit.
Special / systemic Pathology: mempelajari respons
spesifik jaringan atau organ tertentu terhadap
stimulus.
Patologi kali pertama oleh Celsus yang
mempublikasikan suatu penyakit Morgagni abad
18 Virchow menjelaskan penyakit denganperubahan seluler (pertengahan abad 19) semua
penyakit fokus pada abnormallitas perilaku sel
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Empat aspek penyakit yang dipelajari dalam patologi:
Etiologi or cause
pathogenesis
perubahan morfologi
manifestasi klinis
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Etiologi: penyebab, dibagi 2:
Intrinsik atau genetik
didapat (acquired)
Pathogenesis: urutan terjadinya respons sel atau jaringanterhadap suatu agent penyebab, mulai dari stimulus awalsampai timbulnya suatu penyakit.
Perubahan Morfologi: perubahan struktural pada sel ataujaringan, yang merupakan karakteristik suatu penyakit.
Manifestasi Klinis: perubahan morfologi yang terjadi padaberbagai jaringan / organ mempengaruhi fungsi danmenentukan gambaran klinis, perjalanan dan prognosissuatu penyakit.
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VARIATIONOUTSIDENORMALRANGE
DISEASE PATHOLOGY MEDICINE ANDSURGERY
1. CAUSES(ETIOLOGY)
2. PATHOGENESIS(MECHANISME)
3. MORPHOLOGYCHANGE CELL &MOLECULAR
4. SIGN ANDSYMPTOM OF
DISEASE
DIAGNOSTICPROGNOSTIC,THERAPY ANDPROPHYLAXIS
(+PHARMOCOLOGY)
SCIENTIFIC STUDY CLINICAL PRACTICE
1+2+3 PATHOBIOLOGY
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PATOBIOLOGIIlmu yang mempelajari tentang struktur
biologi & fungsi yang bervariasi dari yang
disebut abnormal dan menimbulkan efekyang disebut penyakit
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1. CELLULAR ADAPTATIONS, CELL INJURY AND CELL
DEATH
2. INFLAMMATION AND REPAIR
3. HEMODYNAMIC DISORDERS
4. INFECTIOUS DISEASES
5. NEOPLASIA
GENERAL PATHOLOGY
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CELLULAR ADAPTATIONS, CELL INJURY, AND
CELL DEATH
Describe cellular adaptations of growth anddifferentiation : hyperplasia, hypertrophy, atrophy,
metasplasia and dysplasia
List the causes of cell injury
List the mechanisms of cell injury
Describe the morphological changes associated with
reversible and irreversible injury
Describe the differences between apoptosis and necrosis
Describe subcellular responses to injury
Describe intracellular accumulations
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INFLAMMATION AND REPAIR
Definition of inflammation
Causes of acute and chronic inflammation
Describe chemical mediators of inflammation
Describe briefly how the microscopic features of acute
inflammation differ from those of chronic inflammation
Describe outcomes of acute inflammation due to a pyogenic
micro-organism
Define the terms resolution; suppuration; organisation
Describe the microscopic features of granulomatousinflammation and give 2 examples
Name two local, and two general, causes for a failure of healing
or repair
Describe mechanisms of wound repair and fibrosis
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HEMODYNAMIC DISORDERS
Describe the causes and consequences of oedemaat different sites
Define thrombosis and give the causes andpotential consequences of such an event.
Define embolism and know about the importance ofpulmonary embolism in clinical practice.
Describe possible causes of haemorrhage andpotential outcomes
Define shock and identify the possible causes andmechanisms
Define infarction and describe possible causes
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INFECTIOUS DISEASES
CAUSES: BACTERIAL
VIRUSES
FUNGI PROTOZOA
HELMINTHS
MYCOPLASMAS RICKETTSIAE
CHLAMYDIAE
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NEOPLASIA
Definition of neoplasm Describe nomenclature of tumors
Explain the difference between anaplasia anddysplasia
List four features which distinguish benign frommalignant tumours
Describe causes of cancers
Describe predisposition factors of cancer
Describe molecular basic of cancer
Describe effects of tumors on the host
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SPECIAL / SYSTEMIC PATHOLOGY
SISTEM HEMATO-IMUNOLOGI & LYMFATIK
SISTEM DERMATOMUSKULER
SISTEM ENDOKRIN
SISTEM REPRODUKSI
SISTEM CARDIOVASKULER
SISTEM RESPIRASI
SISTEM GASTROENTEROLOGI
SISTEM UROGENITAL
SISTEM SARAF
SISTEM MATA
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TATA TERTIB PRAKTIKUM
HADIR TEPAT WAKTU
PAKAIAN RAPI & SOPAN BERSEPATU
JAS PRAKTIKUM
1 KELOMPOK 2 MIKROSKOP BINOKULER
1 KELOMPOK 1 BOX PREPARAT
SANKSI KERUSAKKAN PREPARAT
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SANKSI KERUSAKKAN PREPARAT
CUIL DI PINGGIR PREPARAT : Rp.150.000/PREPARAT
PECAH DI TEPI PREPARAT : Rp. 250.000/PREPARAT
PECAH DITENGAH PRAPARAT : Rp.300.000/PREPARAT
HILANG : Rp. 400.000/PREPARAT
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KENAPA MAHAL ???
ADENOFIBROMA OVARII
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ADENOFIBROMA OVARII
CA MAMMA
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CA MAMMA
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Cancers.net
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