NAME_______________________________________

CircleOne:A1A2

SCORE_____________/16MULTIPLECHOICECirclethebestanswerforquestions1-10(1pteach)1. ApieceofdoublestrandedDNAhas30%A,whatwillbethe%ofG?

a. 30%b. 40%c. 20%d. 70%e. notenoughinformationtoanswer

2. YouhaveapieceofDNAwiththesequenceATGC.Fromthisyouknow,

a. Aisatthe5’endb. Aisatthe3’endc. Acouldbeateitherthe5’endorthe3’endofDNAd. Youhaveapalindromicsequencee. Noneoftheabove

3. Whichofthefollowingbasespairswithguanine?

a. Adenineb. Guaninec. Cytosined. Uracile. Thymine

4. Thenitrogenousbaseislinkedtotheriboseordeoxyribosesugarviaa

a. Glycosidicbondb. Amidebondc. Hydrogenbondd. Phosphoanhydridebonde. Phosphodiesterbond

5. GenomicDNAis_______resultingintheproductionof_______.

a. TranscribedmRNAb. Translated,tRNAc. Transcribed,DNAd. Translated,proteine. Replicated,mRNA

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6. _______istheadaptorthatiskeytoconvertingthetripletcodonsofmRNAintotheproteinpolymers.

a. tRNAb. rRNAc. mRNAd. siRNAe. lcRNA

7. Whichofthefollowingstatementsaboutdouble-strandedDNAisfalse?

a. Thebackbonecontainsalternatingribosesugarandphosphategroups.b. Thetwostrandshaveanantiparallelorientation.c. Thehelixhastwogroovescalledthemajorgrooveandtheminorgroove.d. Thebasesareontheoutsideofthehelix.e. Thestrandsareformedbynucleotideslinkedtogetherviaphosphodiester

bonds.

8. Inthepicturebelow,arrowlabeled1correspondsto______andarrow2correspondsto_________.

a. Replication,transcriptionb. Translation,transcriptionc. Mutation,replicationd. Transcription,replicatione. Transcription,translation

9. Inthepicturebelow,whichlabel(s)ontheleftrefertothetemplatestrand?a. 1b. 2c. mRNAd. both1and2aretemplatestrandse. both1andmRNAarethetemplatestrands

10. WhichofthefollowingstatementsareTRUE?

a. ThemRNAistranslatedfrom5’tothe3’endb. ThemRNAistranslatedfrom3’to5’endc. Duringtranscription,themRNAissynthesizedinthe3’à5’directiond. AandCarebothtruee. BandCarebothtrue

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SHORTANSWER.Followdirectionswitheachquestion.11. Forthebasepairshownbelow,answerthefollowingquestions.(6pts)

a. Shownaboveis(circleallthatapply).

Adenosine Guanosine Cytidine Uridine Thymidine

b. Drawhydrogenbondsbetweenthebasesasdashedordottedlines.c. CIRCLEthegroupthatisthemajordifferencebetweenuridineandthymine.d. Drawanarrowtotheglycosidiclinkageofthepurine.e. Drawasquarearoundthe5’-carbonofthepyrimidine.

12. ThefollowingpieceofdoublestrandedDNAencodesaveryshortpeptide.Inthespace

below,writethesequenceofmRNAthatwouldbesynthesizedbyRNApolymerasefromthispieceofDNAifthebottomstrandisthetemplate.Thenwritetheproteinsequenceinone-lettercodethatwouldbesynthesizedbytheribosomefromthatmRNAusingthefirstreadingframe(useGeneticCodeTablebelow).(0pts)5’- ATGGCTGGGTGCTTTTAA-3’ 3’ –TACCGACCCACGAAAATT-5’mRNAsequence:AUG GCU GGG UGC UUU UAAProteinsequence:MAGCF

N

NN

N

NH2

O

HO

HH

HH

O

O

H O

H H

H H

O

N

HN

O

O