Hannover Medical School Hannover Biomedical Research School
HBRSHBRSHBRSHBRS
Curriculum
MD/PhD Program “Molecular Medicine”
PhD program “Infection Biology” “Miditrain” EST Marie Curie (GBF)
European Research Training group (EGRK) “Pseudomonas: Pathogenicity and Biotechnology”
Research Training group (GRK 705)
”Characterization of pathophysiological animal models”
Winter and Summer Semester 2005/2006
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Hannover Medical School Hannover Biomedical Research School
HBRSHBRSHBRSHBRS
Curriculum
MD/PhD Program “Molecular Medicine”
PhD program “Infection Biology” “Miditrain” EST Marie Curie (GBF)
European Research Training group (EGRK) “Pseudomonas: Pathogenicity and Biotechnology”
Research Training group (GRK 705) ”Characterization of pathophysiological animal models”
Winter and Summer Semester 2005/2006
www.mh-hannover.de/hbrs.html
http://www.gbf.de/miditrain
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PhD Curriculum Hannover Medical School
Academic Year Winter Semester 2005/2006 Start: October 17th, 2005 End: February 20th, 2006 MD/PhD “Molecular Medicine” intermediate examination: until February, 28th PhD “Infection Biology” intermediate examination: March/April 2006 Summer Semester 2006 Start: April 3rd, 2006 End: July 17th, 2006
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Dean of the HBRS and chairman of MD/PhD “Molecular Medicine”: Reinhold E. Schmidt, MD Tel.: 0049-511-532-6656 Professor of Medicine and Immunology Fax: 0049-511-532-9067 Medizinische Hochschule Hannover Carl-Neuberg-Str. 1 D-30625 Hannover E-mail: [email protected] ------------------------------------------------------------------------------------- Scientific Coordination of HBRS and MD/PhD “Molecular Medicine”: Dr. Susanne Kruse and Marlies Daniel HBRS Office of the MHH Tel.: 0049-511-532-6011 Präsidalamt Fax: 0046-511-532-2611 Carl-Neuberg-Str. 1 D-30625 Hannover E-mail: [email protected], [email protected] ------------------------------------------------------------------------------------- Chairman of ZIB: Prof. Dr. Reinhold Förster Institute of Immunology Medizinische Hochschule Hannover Carl-Neuberg-Str. 1 D-30625 Hannover E-mail: [email protected] Scientific Coordination of ZIB: Dr. Sabine Johann and Natalie Evans Zentrum für Infektionsbiologie - ZIB Institute of Immunology Medizinische Hochschule Hannover Carl-Neuberg-Str. 1 D-30625 Hannover E-mail: [email protected]
http://www.mh-hannover.de/hbrs.html http://www.gbf.de/miditrain
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Members of the MD/PhD “Molecular Medicine” Commission: Prof. Dr. Reinhold E. Schmidt (Chairman) Prof. Dr. Achim Gossler (Vice Chairman) Prof. Dr. Christopher Baum Prof. Dr. Ernst-Georg Brabant Prof. Dr. Matthias Gaestel Dr. Elmar Jäckel Prof. Dr. Christoph Klein Prof. Dr. Ralf Lichtinghagen HD Dr. Beate Sodeik PD Dr. Thomas Tschernig Dr. Dorothea Gadzicki Dr. Murat Ünalan NN
Contact/coordination: Dr. Susanne Kruse and Marlies Daniel, Medizinische Hochschule Hannover, MD/PhD Office, OE 9117, Carl-Neuberg-Str. 1, 30625 Hannover; Tel. +49-511-532-6011; Fax. -2611; [email protected], [email protected] Members of the PhD program “Infection Biology“ and Faculty: Prof. Dr. Reinhold Förster (Chairman) Prof. Dr. Nina Baltes PD Dr. Franz-Ch. Bange Dr. Günter Bernhardt Prof. Dr. Ursula Bilitewski Prof. Dr.med. Jan Buer Dr. Dirk Bumann Prof. Singh Chatwal Dr. Kurt Dittmar Prof. Dr. Gerald-F. Gerlach Dr. Markus Gräler Dr. Mathias Gunzer Dr. Florian Gunzer Dr. Carlos Guzman Dr. Hansjörg Hauser Dr. Susanne Häußler Prof. Dr. H. Hedrich Dr. Hans Heiken Prof. Dirk Heinz Prof. Dr. Georg Herrler Dr. Christine Josenhans Prof. Dr. Andreas Klos Dr. Andreas Lengeling Prof. Dr. Edgar Maiß Prof. Dr. Dietmar Manstein Prof. Dr. Martin Messerle Prof. Dr. Volker Moennig Dr. Werner Müller Dr. Oliver Pabst Dr. Klemes Rottner Prof. Dr. von Samson-Himmeldtjerna Prof. Dr. Brigitte Schlegelberger Prof. Dr. Reinhold E. Schmidt Prof. Dr. Thomas Schnieder Prof. Dr. Thomas F. Schulz Prof. Dr. Stefan Schwarz PD Dr. Beate Sodeik Dr. Theresia Stradal Prof. Dr. Sebastian Suerbaum Prof. Dr. Ernst Ungewickell Dr. Annette Wagner Prof. Dr. Jürgen Wehland Prof. Dr. Valentin-Weigand Dr. Siegfried Weiss Dr. Dagmar Wirth
Contact/coordination: Natalie Evans, Medizinische Hochschule Hannover, Institute of Immunology, OE 5240, Carl-Neuberg-Str. 1, 30625 Hannover; Tel. +49-511-532-9742; Fax. -9722; [email protected] “Miditrain” EST (Marie Curie), GBF Braunschweig Prof. Dr. H. J. Hauser (chairman) Dr. Andreas Lengeling
Dr. Siegfried Weiss
Contact/coordination: Dr. Sabine Kirchhoff, GBF, Mascheroder Weg 1, 38124 Braunschweig; Tel. +49-532-6181731; Fax. -1262; [email protected] GRK 705: „Characterization of pathophysiological animal models” Prof. Dr. H. Hedrich (chairman)
Contact/coordination: PD Dr. Marie-Luise Enss, Medizinische Hochschule Hannover, Institute of Animal Sciences, OE 8600, Carl-Neuberg-Str. 1, 30625 Hannover; Tel. +49-511-532-3748; Fax. -3710; [email protected] European Research Training group „Pseudomonas: Pathogenicity and Biotechnology” Prof. Dr. B. Tümmler (speaker in Hannover)
Contact/coordination: Helga Riehn-Kopp, Medizinische Hochschule Hannover, Pediatric Pneumology, OE 6711, Carl-Neuberg-Str. 1, 30625 Hannover; Tel. +49-511-532-2920; Fax. -6723; [email protected]
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Content: Page Obligatory seminars for PhD programs ....................................................... 9 1st Semester (MD/PhD and PhD “Infection Biology”) ................................ 9
- in-depth seminars for medical students............................................................. 12
- in-depth seminars for life scientists ................................................................... 13 2nd Semester ........................................................................................................ 14 - second half for PhD “Infection Biology”..........................................................16 3rd Semester MD/PhD “Molecular Medicine” ............................................ 17
- Focus Immunology............................................................................................. 17
- Focus Genetics and Cell Biology ....................................................................... 20 3rd Semester PhD “Infection Biology”.......................................................... 22 4th Semester MD/PhD “Molecular Medicine” ............................................ 24
- Focus Infection................................................................................................... 24
- Focus Differentiation and Oncology ................................................................. 26 4th Semester PhD “Infection Biology” .......................................................... 28 Obligatory program for the two Research training groups (GRKs) .... 30 Optional courses............................................................................................... 32 Specific seminars ............................................................................................. 33
- organized by the HBRS ...................................................................................... 33 Requirements and Rules ................................................................................ 34 Map ....................................................................................................................... 41
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Curriculum MD/PhD “Molecular Medicine”
Curriculum PhD program “Infection biology”
For all: Seminar, 2h and Tutorial, 1h
1st year
In parallel: special in-depth seminars for medical students and students from life sciences, respectively
Basics in Molecular Medicine (Focus on Methods); Seminar, 2h
Tutorial, 1h
Tutorial for the respective seminar/tutorial series
1st sem. 2nd sem.
2nd year
1. Focus: Immunology
2. Focus: Genetics & Cell Biology
3. Focus: Infection
4. Focus: Differentiation & Oncology
or
or
4th sem. 3rd sem.
3rd year: concentration on individual research projects
Immunology/Bacteriology/ Virology
Cell Biology/ Genetics/ Biochemistry /Methods
1st year
Basics in Molecular Medicine; Seminar 2h
3rd year: concentration on individual research projects
1st sem. 2nd sem.
Immunology/Bacteriology/ Virology
Cell Biology
Project presentation (1h) and Special topic lectures in Infection Biology (1h)
2nd year
1. Focus: Immunology 3rd sem. 4th sem.
Presentation of original manuscripts and reviews
Project reports
Literature seminars and project reports; Seminar, 2h
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Structure of the PhD Program “Infection Biology“
• Sem. + Lect. Monday (16.30 - 18.00 hrs; 6 cp) • Journal Club in students own department (15 h) + attendance of 15 scientific lect. at MHH/GBF/TiHo (such as SFB- Sem. or Immunol. Colloquium; 2 cp)
• Seminar for PhD students based on reviews and original manuscripts (Monday 16.30 – 18.00) (2 cp) • Presentation of one review and one original manuscript during these seminars (2 cp)
• 3-year PhD project work (125 cp) • Three presentations in department over three years (10 cp) • Three presentations of manuscripts at the departments Journal Club over three years (3 cp) • Talk / presentation at international congress (2 cp) • Practical courses (2 x 4 days or 3 x 3 days) (12 cp) • Participation in summer schools / interdisciplinary seminars / congress (2 cp per 20h)
Intermediate exam after 18 months
PhD thesis and final exam after 3 yearscp: credit points
Year 1 Year 2 Year 3
• Sem. + Lect. In basic sciences Monday (16.30 - 18.00 hrs; 6 cp) •Tutorials Monday; till Christmas separate tutorials for edical students and life scientists (3.30 – 4.30 hrs; 2 cp) • Complex and clinical system;
choice between the foci Immunology, Infection, Oncology and Differentiation, Cell Biology/Genetics, Biochemistry Mondays, Seminar and Tutorial (3.00 – 6.00; 8 cp)
• 3-year PhD project work (125 cp) • Three presentations in department over three years (10 cp) • Three presentations of manuscripts at the departments Journal Club over three years (3 cp) • Public annual presentation/project report (10 cp) •Talk / presentation at international congress (2 cp) • Project-orientated seminars/courses; including practicals (80 h, 8 cp)
Intermediate exam after 18 months
PhD thesis and final exam after 3 yearscp: credit points
Year 1 Year 2 Year 3
Structure of the MD/PhD program “Molecular Medicine“
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Obligatory 1st Semester Joint Curriculum MD/PhD ”Molecular Medicine” and PhD “Infection Biology” Note: The curriculum of the first year is more orientated towards basics and methods in the different diciplines. MD/PhD “Molecular Medicine”: There are some alternative in-depth seminars/ tutorials on Mondays for medical students and students from life sciences till Christmas (see pages 12/13) and the respectives tutorial for the seminars. PhD “Infection Biology”: you are very welcome to attend the tutorials, but this is not a must!! For everyone!!
Welcome: General introduction, lectures, expectations etc.; answering of all questions
Achim Gossler, Susanne Kruse
Monday, 24.10.05
3.45 – 4.30 p.m.
1 hr
1.) General Immunology
Structure and components of the immune system, Janeway Chapter 1-2 Reinhold Förster
Monday, 24.10.05
4.30 – 6 p.m.
2 hrs
Recognition structures, Janeway Chapter 4,5 Robert Lindner
Monday, 31.10.05
4.30 – 6 p.m.
2 hrs
Adaptive immune responses, Janeway Chapter 9 Horst Bernhardt
Monday, 07.11.05
4.30 – 6 p.m.
2 hrs
Innate immunity, Janeway Chapter 12-13 Reinhold E. Schmidt
Monday, 14.11.05
4.30 – 6 p.m.
2 hrs
Development of the immune system Janeway Chapter (7), 8
Christoph Klein
Monday, 21.11.05
4.30 – 6 p.m.
2 hrs
10
2.) General Bacteriology
Introduction to Medical Microbiology: Common themes in bacterial pathogenesis Sebastian Suerbaum
Monday 28.11.05
4.30 – 6 p.m.
2 hrs
Gram-positive pathogens (Staphylococci, Streptococci, Listeria, Clostridia etc.) Jan Buer
Monday, 05.12.04
4.30 – 6 p.m.
2 hrs
Gram-negative pathogens (Enterobacteriaceae, Helicobacter etc.) Christine Josenhans
Monday, 12.12.05 4.30 – 6 p.m.
2 hrs
Mycobacteria and Chlamydia, Mycoplasma, Spirochetes Franz C. Bange and Andreas Klos
Monday, 19.12.05
4.30 – 6 p.m.
2 hrs
Tutorial. Bacterial population genetics Sebastian Suerbaum
Monday, 09.01.06 3.30-4.15 p.m
1 hr
Diagnostic procedures in Medical Microbiology; Introduction to Antibiotics and Chemotherapy Florian Gunzer
Monday, 09.01.06
4.30 – 6 p.m.
2 hrs
Tutorial Gunzer Monday, 16.01.06 3.30-4.15 p.m
1 hr
Introduction into Medical Parasitology von Samson (TiHo)
Monday 16.01.06
4.30 – 6 p.m.
2 hrs
3.) General Virology
Tutorial von Samson: Medical Parasitology Monday, 23.01.06 3.30 – 4.15 p.m
1 hr
Overview: Virus families and viral diseases Albert Heim
Monday, 23.01.06 4.30 – 6 p.m
2 hrs
Tutorial Heim: Viruses and viral diseases Monday, 30.01.06 3.30 – 4.15 p.m
1 hr
Attachment and entry Beate Sodeik
Monday, 30.01.06 4.30 – 6 p.m
2 hrs
Tutorial Sodeik Monday, 06.02.06 3.30 – 4.15 p.m
1 hr
11
RNA virus genome replication Georg Herrler
Monday, 06.02.06 4.30 – 6 p.m
2 hrs
Tutorial Herrler Monday, 13.02.06 3.30 – 4.15 p.m
1 hr
DNA virus genome replication, viral gene expression Thomas Schulz
Monday, 13.02.06 4.30 – 6 p.m
2 hrs
Tutorial Schulz Monday, 20.02.05 3.30 – 4.15 p.m
1 hr
Assembly, Egress, Maturation Gert Zimmer
Monday, 20.02.05 4.30 – 6 p.m
2 hrs
Location Hannover Biomedical Research School, MD /PhD seminar room, I 4, 2nd floor, Room 1140
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*only for MD/PhD medical students: Some more basics in Life Sciences As there are not many medical students this year, we will arrange an individual program for you! Or you visit the tutorials for life scientists or PhD “Infection Biology” Mondays, 3.30 – 4.30 p.m. [Microbiology, Developmental Biology (Kispert), Biochemistry (Kotlyarov), Virology (Verhagen), Genetics (Schubert)] Location Hannover Biomedical Research School, I 4, 2nd floor, ask at MD/PhD office
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** only for MD/PhD students from life sciences: some basics in Medicine/Techniques Welcome: see above Monday, 24.10.05
3.45 – 4.30 p.m.
1 hr
Immunodynamics
Matthias Gunzer
Monday, 31.10.05
3.30 – 4.30 p.m.
1 hr
Stem cell directed gene transfer /gene therapy
Peter Horn
Monday, 07.11.05
3.30 –4.30 p.m.
1 hr
Gene therapy, hematological diseases
Li (Dept. Baum)
Monday, 14.11.05
3.30 – 4.30 p.m.
1 hr
Clinal Immunology I: pathogenesis of an autoimmune disease (Lupus erythematosus)
Torsten Witte
Monday 21.11.05
3.30 – 4.30 p.m.
1 hr
Clinical Immunology II: pathogenesis of HIV infection and immunological consequences
Hans Heiken
Monday, 28.11.05
3.30 – 4.30 p.m.
1 hr
Hematology: pathogenesis of an hematological disease
Matthias Eder
Monday, 05.12.05
3.30 – 4.30 p.m.
1 hr
Oncology: Aging
Lenhard Rudolph
Monday, 12.12.05
3.30 – 4.30 p.m.
1 hr
FACS analysis
Roland Jacobs
Monday, 19.12.05
3.30 – 4.30 p.m.
1 hr
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2nd Semester
Joint Curriculum MD/PhD and PhD Infection Biology MD/PhD: please attend the whole of the seminars and tutorials listed below. Note, there is a change of time after the Cell Biology part!! PhD Infection Biology: You should attend the seminars up to May 15th (including the Cell Biology), you are very welcome to attend the tutorials, but this is not a must!! Afterwards you have your own seminars (see page )
Tutorial Zimmer Monday 03.04.06 3.30 – 4.15 p.m.
2 hrs
Viral pathogenesis Martin Messerle
Monday 03.04.06 4.30 – 6 p.m. 2 hrs
4. ) General Cell Biology
Tutorial Messerle Monday, 10.04.06 3.30 – 4.15 p.m
1 hr
Cell Biology I: GTPases Stradal
Monday 10.04.06 4.30 – 6 p.m. 2 hrs
No seminars, public holidays Monday 17.04.06 - -
Tutorial Stradal Monday, 24.04.06 3.30 – 4.15 p.m
1 hr
Cell Biology II: Microtubules Jürgen Wehland
Monday, 24.04.06 4.30 – 6 p.m 2 hrs
No seminars, public holidays Monday 01.05.06 - -
Tutorial Wehland Monday, 08.05.06 3.30 – 4.15 1 hr
Cell Biology III: Cell cycle Hans J. Hauser
Monday, 08.05.06 4.30 – 6 p.m 2 hrs
Now only for MD/PhD!!
5.) Biochemistry and Genetics; methods
Human gene finding; basics of human genes (intro in general genetics, mapping: mouse, human) M. Stuhrmann Spangenberg
Monday, 15.05.06 3 – 5 p.m 2 hrs
15
Tutorial Monday, 15.05.06 5 – 6 p.m 1 hr
NN Monday, 22.05.06 3 – 5 p.m 2 hrs
Tutorial Stuhrmann-Spangenberg Monday, 22.05.06 5 – 6 p.m 1 hr
Strategies to analyse gene function in vivo Achim Gossler
Monday 29.05.06 3 – 5 p.m. 2 hrs
Tutorial NN Monday 29.05.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 05.06.06 - -
Global gene and protein expression profilingBrigitte Schlegelberger
Monday, 12.06.06 3 – 5 p.m 2 hrs
Tutorial Gossler Monday, 12.06.06 5 – 6 p.m 1 hr
MAP-kinases
Alexey Kotlyarov
Monday, 19.06.06 3 – 5 p.m 2 hrs
Tutorial Schlegelberger Monday, 19.06.06 5 – 6 p.m 1 hr
Protein & membrane trafficking (exocytosis, membrane fusion, organell biosynthesis)
Ernst Ungewickell
Monday, 26.06.06 3 – 5 p.m 2 hrs
Tutorial Kotlyarov Monday, 26.06.06 5 – 6 p.m 1 hr
Proteomics applied to clinical research and diagnostics
Eva Mischak-Weissinger
Monday, 03.07.06 3 – 5 p.m 2 hrs
Tutorial Ungewickell Monday, 03.07.06 5 – 6 p.m 1 hr
Spectroscopy, hydrodynamics, structure, imaging
Claus Urbanke
Monday, 10.07.06 3 – 5 p.m 2 hrs
Tutorial Mischak-Weissinger Monday, 10.07.06 5 – 6 p.m 1 hr
Tutorial Urbanke Monday, 17.07.05 5 – 6 p.m 1 hr
Location Hannover Biomedical Research School, I 4, 2nd floor, Room 1140 (MD/PhD seminar room) For all MD/PhD students: A block course of 1 week in Bioinformatics is planned.
16
2nd Semester
PhD Infection Biology Time: 4.30 – 6 p.m.
08.05.2006 Project Presentation 1 Project Presentation 2 Topic Focus I 15.05.2006 Project Presentation 3
Project Presentation 4 Topic Focus II 22.05.2006 Project Presentation 5
Project Presentation 6 Topic Focus III 29.05.2006 Project Presentation 7
Project Presentation 8 Topic Focus IV 06.06.2006 Project Presentation 9
Project Presentation 10 Topic Focus V 12.06.2006 Project Presentation 11
Project Presentation 12 Topic Focus VI 19.06.2006 Project Presentation 13
Project Presentation 14 Topic Focus VII 26.06.2006 Project Presentation 15
Project Presentation 16 Topic Focus VIII 03.07.2006 Project Presentation 17
Project Presentation 18 Topic Focus IX 10.07.2006 Project Presentation 19
Project Presentation 20 Topic Focus X
Location Department of Microbiology, building I6, level 5, seminar room
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3rd Semester
MD/PhD program “Molecular Medicine” Note: The curriculum of the second year is more orientated towards research and applied aspects in the different diciplines. Every student has the choice between two major foci each semester. You may vary in the choice of modules between the two foci. Please, choose the ones most appropriate for you and your project! 1. Focus: Immunology
1. Immune cells and organs
T and B cell differentiation Fritz Melchers (Berlin/Basel) and tutorial 5-6 p.m.
Monday 24.10.05 3 – 5 p.m. 2 hrs
Tutorial Melchers
Functional organization in lymphoid organs Reinhold Förster
Monday, 31.10.05 3 – 5 p.m 2 hrs
Tutorial Förster Monday, 31.10.05 5 – 6 p.m 1 hr
Differentiation of dendritic cells and macrophages
Christoph Klein
Monday, 07.11.05 3 – 5 p.m 2 hrs
No tutorial Monday, 07.11.05 5 – 6 p.m 1 hr
Regulation and function of NK cells Roland Jacobs
Monday, 14.11.05 3 – 5 p.m 2 hrs
Tutorial C. Klein Monday, 14.11.05 5 – 6 p.m 1 hr
2. Autoimmunity
Autoimmunity, tolerance, negative selection Elmar Jäckel
Monday 21.11.05 3 – 5 p.m. 2 hrs
Tutorial Jacobs Monday 21.11.05 5 – 6 p.m 1 hr
The complement system – the regulation of anaphylatoxin receptors Andreas Klos
Monday, 28.11.05 3 – 5 p.m 2 hrs
Tutorial Jaeckel Monday, 28.11.05 5 – 6 p.m 1 hr
Fc-mediated mechanisms in autoimmune disease Engelbert J. Gessner
Monday, 05.12.05 3 – 5 p.m 2 hrs
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Tutorial Klos Monday, 05.12.05 5 – 6 p.m 1 hr
3. Allergy and Asthma
Mechanisms in allergic inflammation (asthma) Norbert Krug (Fraunhofer Institute)
Monday 12.12.05 3 – 5 p.m. 2 hrs
Tutorial Gessner Monday 12.12.05 5 – 6 p.m 1 hr
Neuroimmune interactions in asthma bronchiale Armin Braun (Fraunhofer Institute)
Monday, 19.12.05 3 – 5 p.m 2 hrs
Tutorial Krug Monday, 19.12.05 5 – 6 p.m 1 hr
Immunobiology of eczematous skin disease Miriam Wittmann
Monday, 09.01.06 3 – 5 p.m 2 hrs
Tutorial Braun Monday, 09.01.06 5 – 6 p.m 1 hr
4. Innate Immunity
Innate immunity (Toll-like receptors) Hansjörg Hauser (GBF)
Monday 16.01.06 3 – 5 p.m. 2 hrs
Tutorial Wittmann Monday 16.01.06 5 – 6 p.m 1 hr
Immune response in HIV Reinhold E. Schmidt
Monday, 23.01.06 3 – 5 p.m 2 hrs
Tutorial Hauser Monday, 23.01.06 5 – 6 p.m 1 hr
Transfer of DNA through bacteria Siegfried Weiss (GBF)
Monday, 30.01.06 3 – 5 p.m 2 hrs
Tutorial Schmidt Monday, 30.01.06 5 – 6 p.m 1 hr
5. Signaling and therapy
Post transcriptional gene regulation Helmut Holtmann
Monday 06.02.06 3 – 5 p.m. 2 hrs
Tutorial Weiss Monday 06.02.06 5 – 6 p.m 1 hr
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Regulation of immune responses by CD45 molecules Reinhard Schwinzer
Monday, 13.02.06 3 – 5 p.m 2 hrs
Tutorial Holtmann Monday, 13.02.06 5 – 6 p.m 1 hr
Major Histocompatibility complex as key for adoptive immunotherapy R. Blasczyk und B. Elz-Vesper
Monday, 20.02.06 3 – 5 p.m 2 hrs
Tutorial Schwinzer Monday, 20.02.06 5 – 6 p.m 1 hr
Tutorial Blasczyk Monday, 27.02.06 5 – 6 p.m 1 hr
Location Building I4, level SO (ground floor), seminar room (right to the main entrance)
20
2. Focus: Genetics and Cell Biology
1. Techniques and diagnostics/therapy
Structure and function of erythrocyte membrane proteins A. Seltsam
Monday 24.10.05 3 – 5 p.m. 2 hrs
No tutorial
A rationale approach to quantitative PCR and chip techniques exemplified in diagnosis of transplant rejection Jürgen Strehlau
Monday, 31.10.05 3 – 5 p.m 2 hrs
Tutorial Seltsam Monday, 31.10.05 5 – 6 p.m 1 hr
Engineering and design of enzymes Jürgen Alves
Monday, 07.11.05 3 – 5 p.m 2 hrs
Tutorial Strehlau Date to be annouced
Embryonic and somatic cloning in mammals Heiner Niemann (Mariensee)
Monday, 14.11.05 3 – 5 p.m 2 hrs
Tutorial Alves Monday, 14.11.05 5 – 6 p.m 1 hr
2. Genetics
The genetics of Morfan syndrome and related disorders Jörg Schmidtke
Monday 21.11.05 3 – 5 p.m. 2 hrs
Tutorial Niemann Monday 21.11.05 5 – 6 p.m 1 hr
The dissection of the endocytic machinery by RNAi Ernst Ungewickell
Monday, 28.11.05 3 – 5 p.m 2 hrs
Tutorial Arslan (group Schmidtke) Monday, 28.11.05 5 – 6 p.m 1 hr
Molecular biology of heart failure Denise Hilfiker
Monday, 05.12.05 3 – 5 p.m 2 hrs
Tutorial Ungewickell Monday, 05.12.05 5 –6 p.m 2 hr
3. Transmembrane Signaling
Antigen processing, MHC II trafficking and the lipid environment Robert Lindner
Monday 12.12.05 3 – 5 p.m. 2 hrs
21
Tutorial Hilfiker Monday 12.12.05 5 – 6 p.m 1 hr
Stress-dependent signal transduction in eukaryotic cells Matthias Gaestel
Monday, 19.12.05 3 – 5 p.m 2 hrs
Tutorial Lindner Monday, 19.12.05 5 – 6 p.m 1 hr
Small GTPases as targets of bacterial toxins Harald Genth (group I. Just)
Monday, 09.01.06 3 – 5 p.m 2 hrs
Tutorial Gaestel Monday, 09.01.06 5 – 6 p.m 1 hr
How molecular motors work Dietmar Manstein
Monday 16.01.06 3 – 5 p.m. 2 hrs
Tutorial Genth Monday 16.01.06 5 – 6 p.m 1 hr
4. Cell Biology and disease
Pathophysiology of arterioclerosis Bernhard Schieffer
Monday, 23.01.06 3 – 5 p.m 2 hrs
Tutorial Manstein Monday, 23.01.06 5 – 6 p.m 1 hr
Congenital disorders of glycosylation Francoise Routier
Monday, 30.01.06 3 – 5 p.m 2 hrs
Tutorial Schieffer Monday, 30.01.06 5 – 6 p.m 1 hr
Cancer and genes Brigitte Schlegelberger
Monday 06.02.06 3 – 5 p.m. 2 hrs
Tutorial Routier Monday 06.02.06 5 – 6 p.m 1 hr
Molecular mechanisms of diabetic nephropathy Hermann Haller
Monday, 13.02.06 3 – 5 p.m 2 hrs
Tutorial Schlegelberger Monday, 13.02.06 5 – 6 p.m 1 hr
5. Side aspects
Molecular epidemiology Olaf Dammann
Monday, 20.02.06 3 – 5 p.m 2 hrs
Tutorial Haller (stem cells in renal injury) Monday, 20.02.06 5 – 6 p.m 1 hr
Tutorial Dammann Monday, 27.02.06 5 – 6 p.m 1 hr
Location TPFZ, Research building, ground floor, seminar room 1420 II
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s ce
lls in
viv
o
Rev
iew
IM
Be
ata
Zygm
unt
Liew
: Neg
ativ
e re
gula
tion
of to
ll-lik
e re
cept
or-m
edia
ted
imm
une
resp
onse
s
14.1
1.20
05
Orig
inal
Pap
er IM
W
irth
(IM)
Upn
eet S
andh
u Lu
: Lip
opol
ysac
char
ide
deac
ylat
ion
by a
n en
doge
nous
lipa
se c
ontro
ls G
ram
-neg
ativ
e ba
cter
ia
R
evie
w IM
Kers
tin R
adtk
e M
ills: R
egul
ator
y T
cells
: Frie
nd o
r foe
in im
mun
ity to
infe
ctio
n?
21.1
1.20
05
Orig
inal
Pap
er IM
G
räle
r (IM
) Sv
en-C
hr
Sens
ken
Wal
ther
: Upr
egul
atio
n of
TG
F-β
…pa
rasi
te g
row
th in
hum
an m
alar
ia in
fect
ion
R
evie
w IM
Dav
ide
Ferra
ris
Ran
dolp
h: D
endr
itic-
cell
traffi
ckin
g to
lym
ph n
odes
thro
ugh
lym
phat
ic v
esse
ls
28.1
1.20
05
Orig
inal
Pap
er IM
Fö
rste
r (IM
) Ja
net K
rege
W
ang:
CD
19
regu
late
s B
cell
mat
urat
ion…
in th
e FD
C z
one
of m
urin
e sp
leni
c ge
rmin
al
cent
ers
R
evie
w IM
Dor
othe
a Sc
hmid
t R
eher
man
n: Im
mun
olog
y of
Hep
atiti
s B
Viru
s an
d H
epat
itis
C V
irus
infe
ctio
n
05.1
2.20
05
Orig
inal
Pap
er IM
G
unze
r M. (
IM)
Pete
r Rei
char
dt
Wat
kins
: Fun
ctio
nal c
onne
ctiv
ity b
etw
een
imm
une
cells
med
iate
d by
tunn
elin
g na
notu
bule
s
Rev
iew
IM
C
arol
ine
Zaou
i Sa
lmi:
Cel
l-sur
face
enz
ymes
in c
ontro
l of l
euko
cyte
traf
ficki
ng
12.1
2.20
05
Orig
inal
Pap
er
MB
Chh
atw
al (M
B)
Vane
ssa
Barro
so
Ram
amoo
rti: T
he L
yme
dise
ase
agen
t exp
loits
a ti
ck p
rote
in to
infe
ct th
e m
amm
alia
n ho
st
23
R
evie
w M
B
Step
hani
e W
eiß
Akto
ries:
Bac
teria
l cyt
otox
ins:
targ
etin
g eu
kary
otic
sw
itche
s
19.1
2.20
05
Orig
inal
Pap
er
MB
Bang
e (M
B)
Priy
anka
Nar
ang
Andr
ies:
A d
iary
lqui
nolin
e dr
ug a
ctiv
e on
the
ATP
synt
hase
of M
ycob
acte
rium
tube
rcul
osis
Rev
iew
MB
Pe
ter R
eich
ardt
M
erre
ll: F
ront
al a
nd s
teal
th a
ttack
stra
tegi
es in
mic
robi
al p
atho
gene
sis
09.0
1.20
06
Orig
inal
Pap
er
MB
Suer
baum
(M
B)
Mai
ke d
e Bu
hr
Gre
ssm
ann:
Gai
n an
d lo
ss o
f mul
tiple
gen
es in
Hel
icob
acte
r pyl
ori
R
evie
w M
B
Nic
olas
Fas
nach
t Th
omas
: Mec
hani
sms
of, a
nd b
arrie
rs to
, hor
izon
tal g
ene
trans
fer b
etw
een
bact
eria
16.0
1.20
06
Orig
inal
Pap
er
MB
Ger
lach
(MB)
Ju
lia H
einz
man
n O
gaw
a: E
scap
e of
intra
cellu
lar S
hige
lla fr
om a
utop
hagy
Rev
iew
MB
Ja
net K
rege
D
obrin
dt: G
enom
ic is
land
s in
pat
hoge
nic
and
envi
ronm
enta
l mic
roor
gani
sms.
23.0
1.20
06
Orig
inal
Pap
er
MB
Klos
(MB)
Ka
y Jo
hsw
ich
Bade
r: R
ecog
nitio
n of
ant
imic
robi
al p
eptid
es b
y a
bact
eria
l sen
sor k
inas
e
Rev
iew
MB
U
pnee
t San
dhu
Mot
a: T
he b
acte
rial i
njec
tion
kit:
type
III s
ecre
tion
syst
ems
30.0
1.20
06
Orig
inal
Pap
er
MB
Gun
zer F
. (M
B)
Dor
othe
a Sc
hmid
t Vo
lkm
an: T
uber
culo
us g
ranu
lom
a fo
rmat
ion
is e
nhan
ced
by a
myc
obac
teriu
m v
irule
nce
::
Rev
iew
MB
N
uno
Vieg
as
Back
hed:
Hos
t-bac
teria
l mut
ualis
m in
the
hum
an in
test
ine.
06.0
2.20
06
Orig
inal
Pap
er
MB
Jose
nhan
s (M
B)
Dav
ide
Ferra
ris
Mar
keto
n: P
lagu
e ba
cter
ia ta
rget
imm
une
cells
dur
ing
infe
ctio
n
Rev
iew
MB
Ju
lia P
ulve
rer
Boye
r L: T
arge
ting
of h
ost-c
ell u
biqu
itin
and
ubiq
uitin
-like
pat
hway
s by
bac
teria
l fac
tors
13.0
2.20
06
Orig
inal
Pap
er
VIR
So
deik
(VIR
) Ke
rstin
Rad
tke
Pelk
man
s: K
inas
es a
. vira
l end
ocyt
osis
Rev
iew
VIR
Julia
Hei
nzm
ann
Smith
: How
viru
ses
ente
r cel
ls
20.0
2.20
06
Orig
inal
Pap
er
VIR
G
uzm
an (V
IR)
Beat
a Zy
gmun
t Va
ccin
e de
velo
pmen
t
Rev
iew
VIR
Kay
Johs
wic
h Va
ccin
e de
velo
pmen
t L
ocat
ion:
TPF
Z, R
esea
rch
build
ing,
gro
und
floor
, sem
inar
roo
m 1
420
I (or
sem
inar
roo
m V
irol
ogy,
I6, l
evel
6)
4th Semester
MD/PhD program “Molecular Medicine”
3. Focus: Infection
1. Viruses and disease
From Virus pathogenesis to viral therapies Christopher Baum
Monday 03.04.06 3 – 5 p.m. 2 hrs
No tutorial
The role of the host cytoskeleton during Herpes simplex virus infection Beate Sodeik
Monday, 10.04.06 3 – 5 p.m 2 hrs
Tutorial Baum Monday, 10.04.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 17.04.06
Viral hepatitis: from immunopathogenesis to immunotherapy Heiner Wedemeyer
Monday, 24.04.06 3 – 5 p.m 2 hrs
Tutorial Sodeik Monday, 24.04.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 01.05.06
2. Bacteria and disease
Helicobacter pylori infection Sebastian Suerbaum
Monday 08.05.06 3 – 5 p.m. 2 hrs
Tutorial Wedemeyer Monday 08.05.06 5 – 6 p.m 1 hr
The role of the metabolism in the pathogenesis of tuberculosis Franz-C. Bange
Monday, 15.05.06 3 – 5 p.m 2 hrs
Tutorial Suerbaum Monday, 15.05.06 5 – 6 p.m 1 hr
Pathogenicity of EHEC disease Florian Gunzer
Monday, 22.05.06 3 – 5 p.m 2 hrs
Tutorial Bange Monday, 22.05.06 5 – 6 p.m 1 hr
3. Genetics and disease
Medical genomics Jan Buer
Monday 29.05.06 3 – 5 p.m. 2 hrs
25
Tutorial Gunzer Monday 29.05.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 05.06.06
Genetic susceptibility to infectious disease Burkhard Tümmler
Monday, 12.06.06 3 – 5 p.m 2 hrs
Tutorial Buer Monday, 12.06.06 5 – 6 p.m 1 hr
Functional and comparative genomics of infectious diseases Andreas Lengeling (GBF)
Monday, 19.06.06 3 – 5 p.m 2 hrs
Tutorial Tümmler Monday, 19.06.06 5 – 6 p.m 1 hr
4. Infection and immune system
Host-pathogen interactions Jürgen Wehland (GBF)
Monday 26.06.06 3 – 5 p.m. 2 hrs
Tutorial Lengeling Monday 26.06.06 5 – 6 p.m 1 hr
The Mycoplasma-derived lipopeptide MALP-2 is a promising adjuvant for the development of mucosal vaccines against HIV/AIDS Carlos Guzman (GBF)
Monday, 03.07.06 3 – 5 p.m 2 hrs
Tutorial Wehland Monday, 03.07.06 5 – 6 p.m 1 hr
Can we cure AIDS? Christopher Baum
Monday, 10.07.06 3 – 5 p.m 2 hrs
Tutorial Guzman Monday, 10.07.06 5 – 6 p.m 1 hr
Tutorial Baum Monday, 17.07.06 5 – 6 p.m 1 hr
Location Building I4, level SO (ground floor), seminar room (right to the main entrance)
26
4. Focus: Differentiation and Oncology
1. Development and cancer
[Achim Gossler] Monday 03.04.06 3 – 5 p.m. 2 hrs
No tutorial
T-box genes in development and disease Andreas Kispert
Monday, 10.04.06 3 – 5 p.m 2 hrs
Tutorial Monday, 10.04.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 17.04.06
From fly to cancer Nils v. Neuhoff
Monday, 24.04.06 3 – 5 p.m 2 hrs
Tutorial Kispert Monday, 24.04.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 01.05.06
Epigenetics in cancer Ulrich Lehmann
Monday 08.05.06 3 – 5 p.m. 2 hrs
Tutorial v. Neuhoff Monday 08.05.06 5 – 6 p.m 1 hr
2. Stem cells and cancer
Tumor stem cells Hans-H. Kreipe (seminar room Pathology!!)
Monday, 15.05.06 3 – 5 p.m 2 hrs
Tutorial Lehmann Monday, 15.05.06 5 – 6 p.m 1 hr
Inborn errors in hematopoiesis Karl Welte
Monday, 22.05.06 3 – 5 p.m 2 hrs
Tutorial Kreipe Monday, 22.05.06 5 – 6 p.m 1 hr
Organogenesis and stem cell differentiation of the liver Michael Ott
Monday 29.05.06 3 – 5 p.m. 2 hrs
Tutorial Welte Monday 29.05.06 5 – 6 p.m 1 hr
No seminars, public holidays Monday 05.06.06
Embryonic and adult stem cells: strategies for pancreatic and hepatic differentiation Anna Wobus (Gatersleben)
Monday, 12.06.06 3 – 5 p.m 2 hrs
27
Tutorial Wobus Monday, 12.06.06 5 – 6 p.m 1 hr
3. Signaling and cancer
Cytokine-receptor signaling, oncogenes and myeloproliferation Matthias Eder
Monday, 19.06.06 3 – 5 p.m 2 hrs
Tutorial Ott Monday, 19.06.06 5 – 6 p.m 1 hr
RNAi-based target validation in hematopoietic cells Michaela Scherr
Monday 26.06.06 3 – 5 p.m. 2 hrs
Tutorial Eder Monday 26.06.06 5 – 6 p.m 1 hr
The role of telomere shortening and telomerase in aging, regeneration and cancer Lenhard Rudolph
Monday, 03.07.06 3 – 5 p.m 2 hrs
Tutorial Scherr Monday, 03.07.06 5 – 6 p.m 1 hr
Regulation of cell cycle progression and tumor development by the cyclin kinase inhibitor/tumor suppressor protein p27 Nisar Malek
Monday, 10.07.06 3 – 5 p.m 2 hrs
Tutorial Rudolph Monday, 10.07.06 5 – 6 p.m 1 hr
Tutorial Malek Monday, 17.07.06 5 – 6 p.m 1 hr
Location to be announced
4th S
emes
ter
PhD
pro
gram
“In
fect
ion
Bio
logy
”
Tim
e: 4
.30
– 6
p.m
.
DA
TE
FOC
US
SUPE
RVI
SOR
STU
DEN
T SU
BJE
CT
03
.04.
2006
O
rigin
al P
aper
CB
Hau
ser (
CB)
Ju
lia P
ulve
rer
TBA
R
evie
w C
B
Hei
ke d
e Bu
hr
Barb
acid
: To
cycl
e or
not
to c
ycle
: A c
ritic
al d
ecis
ion
in c
ance
r
10.0
4.20
06
Orig
inal
Pap
er C
B W
ehla
nd (C
B)
Car
olin
e Za
oui
Ree
ves:
Dis
ablin
g po
xviru
s pa
thog
enes
is b
y in
hibi
tion
of A
bl-fa
mily
tyro
sine
ki
nase
s
R
evie
w C
B
Sven
-Chr
. Se
nske
n G
alja
rt: C
lips
and
clap
s an
d ce
llula
r dyn
amic
s
24.0
4.20
06
Orig
inal
Pap
er C
B St
rada
l (C
B)
Step
hani
e W
eiß
Yang
: Mam
mal
ian
CAR
MIL
inhi
bits
acr
in fi
lam
ent c
appi
ng b
y ca
ppin
g pr
otei
n
R
evie
w C
B
Mar
cin
Lysz
kiew
icz
Ros
sman
n: G
ef m
eans
go:
Tur
ning
on
RH
O G
TPas
es w
ith g
uani
ne n
ucle
otid
e..
02.0
5.20
06
Proj
ect P
rese
ntat
ion
I W
eiss
(IM
) M
arci
n Ly
szki
ewic
z to
be
fille
d in
by
ZIB
Sek
reta
riat
Pr
ojec
t Pre
sent
atio
n II
Wei
ss (I
M)
Nun
o Vi
egas
08.0
5.20
06
Proj
ect P
rese
ntat
ion
I M
ülle
r (IM
) N
icol
as F
asna
cht
Pr
ojec
t Pre
sent
atio
n II
Wirt
h (IM
) U
pnee
t San
dhu
15.0
5.20
06
Proj
ect P
rese
ntat
ion
I G
räle
r (IM
) Sv
en-C
hr.
Sens
ken
Pr
ojec
t Pre
sent
atio
n II
Förs
ter (
IM)
Jane
t Kre
ge
29
22.0
5.20
06
Proj
ect P
rese
ntat
ion
I G
unze
r M. (
IM)
Pete
r Rei
char
dt
Pr
ojec
t Pre
sent
atio
n II
Gun
zer M
. (M
B)
Priy
anka
Nar
ang
29.0
6.20
06
Proj
ect P
rese
ntat
ion
I C
hhat
wal
(MB)
Va
ness
a Ba
rroso
Pr
ojec
t Pre
sent
atio
n II
Hei
nz (M
B)
Dav
ide
Ferra
ris
06.0
6.20
06
Proj
ect P
rese
ntat
ion
I G
erla
ch (M
B)
Julia
Hei
nzm
ann
Pr
ojec
t Pre
sent
atio
n II
Klos
(MB)
Ka
y Jo
hsw
ich
12.0
6.20
06
Proj
ect P
rese
ntat
ion
I G
unze
r F.
(MB)
D
orot
hea
Schm
idt
Pr
ojec
t Pre
sent
atio
n II
Hed
rich
(MB)
M
aike
de
Buhr
19.0
6.20
06
Proj
ect P
rese
ntat
ion
I So
deik
(VIR
) Ke
rstin
Rad
tke
Pr
ojec
t Pre
sent
atio
n II
Guz
man
(VIR
) Be
ata
Zygm
unt
26.0
6.20
06
Proj
ect P
rese
ntat
ion
I H
ause
r (C
B)
Julia
Pul
vere
r
Pr
ojec
t Pre
sent
atio
n II
Weh
land
(CB)
C
arol
ine
Zaou
i
03.0
7.20
06
Proj
ect P
rese
ntat
ion
I St
rada
l (C
B)
Step
hani
e W
eiß
10.0
7.20
06
TBA
Loc
atio
n:
Sem
inar
roo
m D
ept.
of V
irol
ogy,
Bui
ldin
g I6
, lev
el 6
European research training group “Pseudomonas”: 1. Colloquium 'Pseudomonas: Pathogenicity and Biotechnology', monthly, Thursdays 18.00 - 19.45; Lecture Hall G
2. Course: Introduction into phylogenomics and microbial genome linguistics 1- to 2 full days; enquiries: Mrs Riehn-Kopp, [email protected] Research training group, GRK 705: Characterization of pathophysiological animal models” 1. Lectures given by the supervisors
Mondays, 4.15 p.m., lecture room, Institute for Laboratory Animal Sciences, MHH Date speaker, institute title
31.10.2005 Prof. Achim Gossler Institute for Molecular Biology, MHH
Transgenic techniques in mice
14.11.2005 Dr. Armin Braun, Fraunhofer Institute, Hannover
GLP and good scientific practice
05.12.2005 Prof. Hans J. Hedrich Institute for Laboratory Animal Sciences, MHH
Model development and control, model definition, characteristics and selection
09.01.2006 Prof. Stephan Steinlechner Zoology, TiHo
Chronobiology
06.02.2006 Dr. Dirk Wedekind Institute for Laboratory Animal Sciences, MHH
Linkage analysis and identification of genes
2. Seminars by invited speakers
Thursdays, 5.15 p.m., lecture room,Central Facility for Laboratory Animals, MHH Date speaker, institute title 13.10.2005 Joachim Wittbroth, PhD EMBL,
Heidelberg Control of proliferation and differentiation in the developing retina
17.11.2005 Dr. Craig P. Smith Schoolof Biological Sciences University of Manchester, UK
Urea transporters: what, when and why?
15.12.2005 Prof. Heinfried Radeke, Pharmazentrum Frankfurt, Johann Wolfgang Goethe Universität Frankfurt
Defining new targets for the treatment of inflammatory diseases: pathological homing and regulatory dendritic cells
19.01.2006 NN NN Special lecture Seminar room, Max Planck Institute, 5 p.m.
06.09.2005
Prof. Raphael Kopan Washington University, St. Louis, USA
Presenilin links Notch and Wnt clocks in the somite
31
3. GK Meetings Thursdays, 4.15 p.m., seminar room, Central Facility for Laboratory Animals 4. “Soft skills”
Date Speaker 24.11.2005 Prof. Gerhard Breves
Institute of Physiology University of Veterinary Medicine Hannover (TiHo)
The successful proposal
01.12.2005 Dr. Angelika Langsch Institute of Food Toxicology, University of Veterinary Medicine Hannover (TiHo)
Alternatives to animal models
16.02.2006 Research students and fellows Violetta Pilorz, Barbara Fuchs and Tanja Arndt
Congress experience
12.–13.01.06 Workshop Projectmanagement, Bergkirchen
5. Pratical courses
Supervisor/location topic participant Andree Bleich, PhD Institute for Laboratory Animal Science, MHH
Micobiological control of laboratory animals
2
Prof. Johannes Gessner Clinical Immunology, MHH
Cellular immunology 6
Prof. Achim Gossler Molecular Biology, MHH
Techniques in molecular genetics 3
Prof. Stephan von Hörsten Anatomy, MHH
Characterization of behaviour
3
Dr. Dirk Wedekind Institute for Laboratory Animal Science, MHH Dr. Matthias Elsner Clinical Biochemistry
Analysis of sequence and genome 3
32
German Classes Wednesdays: 7 p.m. – 8.30 p.m. (beginners); 5.30 p.m. -7 p.m. (advanced); teacher: Mrs Marotz, MD/PhD seminar room
Optional (According to the MHH-Curriculum; see board next to the student’s secretary office) Note: You are welcome to visit most of the seminars/courses organized for the German Biology and Biochemistry students, as well as medical students. You are also welcome to visit seminars/courses offered by all programmes of the HBRS (including the Graduate School of the Veterinary School).
Specific seminars (see special announcements provided by the HBRS office and the respective departments)
Experimental Techniques
- Workshops of the Graduiertenkollegs
- Classical and molecular tumor cytogenetics
- Quantitative analysis of protein and peptid interactions
- Immunological methods in cell biology
- Introduction into molecular pathology
- Fluorescence-in-situ-hybridization (FISH) in the diagnostics of hematologic diseases
- Confocal microscopy
Special Seminars
- Molecular aspects of the hepato- und gastroenterology
- Moleculargenetic diagnostics of inheritable diseases
- Aspects of molecular medicine
- Genexpression and growth control
- Laser in biology, medicine and environmental research
- Quantitative biology: biophysical examples from medicine and biology
- Molecular genetics
- Molecular genetics of development
Radiation protection
33
Organized by the HBRS Office:
Presentation of projects (weekend, 2 days; for MD/PhD: March/April, 2006)
Gene Technology Security (September, 2006)
Introduction to Ethics (weekend workshop; Schmidtke) - Medical Ethics - Ethical aspects of gene technology - Science ethics - Good laboratory practise
Research Ethics (2-day workshop; February/March 2006)
Presentation seminar (2 days, July 2006, Dierks)
Workshop with practical lessons for optimal presentation (lecturers, rhetorical etc.)
Scientific communication/ writing (January 2006, Kruse)
Animal Experiments (November21st-23rd, 2005, Hedrich)
Intercultural communication (2 days, April 2006) Seminars offered by the GBF, Fraunhofer Institute or TiHo: see announcements
Lectures (see special announcements and websites)
Interdisciplinary
- Seminars of the Graduiertenkollegs (including the European Graduate College) - Seminars of the SFBs - Seminars of the PhD program “Infection Biology” - Immunological Kolloquium - Biochemical Kolloquium - Gastroenterology Kolloqium - Microbiological Kolloquium - Kolloquia at GBF - Seminars and Kolloquia at TiHo - Biological and Biochemical Questions (BBQ)
In the departments (a must!!)
- Doktorandenseminare (MD/PhD seminars)
- Journal-Clubs (these should be in English!)
Internal practical courses
The supervisors provide you with special practical trainings if needed.
http://www.mh-hannover.de/hbrs.html http://www.gbf.de/miditrain
34
Requirements and Rules for Postgraduate Studies and Examinations to Obtain a PhD Degree at the Hannover Medical School
On 15 December 2000 the Senate of the Medical School of Hannover resolved the following Requirements and Rules for Postgraduate Studies and Examinations to Obtain a PhD Degree at the Medical School of Hanover (alternatively Dr. rer. nat. for life scientists). (additions on June 4th 2002, February 11th 2004)
Chapter One
Objective of PhD Studies
§ 1 Objective Research studies at the Hannover Medical School (MHH) for the purpose of obtaining a PhD degree (hereinafter referred to as PhD studies) shall facilitate postgraduate training with a focus on specific research projects with a view to enabling the candidate to do in-depth scientific work on his or her own and to provide him or her with additional professional qualifications for future assignments in research or related areas of work. PhD studies shall foster the development of outstandingly gifted up-and-coming academics. The standard time allowed for completing PhD studies shall be three years. Once these PhD studies have been successfully completed, and the PhD examination has been passed, the MHH will award the degree of a Doctor of Philosophy (PhD) or Dr. rer. nat. for natural scientists (not for medical students).
Chapter Two
Requirements for Access and Admission
§ 2 Access (1) Anybody having successfully completed university studies in medicine, veterinary medicine or natural sciences shall have access to PhD studies. (2) Applicants are required to render evidence of above-average results obtained at university. The applicant’s past career must reveal his or her particular qualification for and dedication to scientific work. A physician or dentist will provide evidence of such qualification and dedication by his or her highly expert doctoral thesis in human medicine or dentistry, with at least its experimental or analytical part completed. Decision on whether or not a candidate qualifies for access to PhD studies is up to the PhD Committee (§ 4).
§ 3 Admission to PhD Studies (1) The number of applicants that can be admitted to PhD studies is limited. The number of new applicants admitted annually is 20. The applicants should not be older than 30 years. The PhD Committee shall select the applicants to be admitted (§ 4). As a rule, the President of the MHH will give notice of the date of commencement of PhD studies once a year. (2) The decisive criterion for admission to PhD studies is the overall grade which the student graduated with from university, or the quality of his or her doctoral thesis pursuant to § 2 sub-para. 2. If the number of applicants exceeds the limit, the decision on an applicant’s particular qualification for and dedication to scientific work shall be dependent on a written test (biomedical questions) and on an interview with the PhD Committee and on the quality of the project proposed by him or her, with due consideration of the team’s working conditions. A written protocol of the interview shall be taken. To assess the project, the Committee shall procure an expert report prepared by a university teacher. The result of the interview as well as the quality of the project proposal shall each carry the same weight in the selection of applicants.
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(3) Application papers shall be submitted to the chairperson of the PhD Committee and shall include:
- an informal letter of application for PhD studies indicating the applicant’s particular aptitude and motivation for doing PhD studies and his or her interests and ideas regarding his or her future professional career;
- the application form
- a C.V. including school/university reports and information or certificates on English language skills (and German language skills if applicants are from non-German speaking countries);
- two letters of recommendation
- if applicable: a letter of recommendation prepared by his or her supervisor (§ 4 sub-para. 3) indicating the subject of the research project, confirmation of scientific supervision, confirmation of position, information on planned financing of the research project, and a suggestion for a scientist other than a university teacher to join the co-ordinators’ team (§ 4 sub-para. 3);
- a description of the proposed research project including the most significant aspects of the present state of the art and the project schedule (as agreed with the co-ordinator) or alternatively a detailed description of former research work; the purpose of such description is to demonstrate that this is an ambitious research project promising an important scientific contribution (e.g. Master thesis; medical doctoral thesis)
- designation of the scientific discipline in which the applicant intends to acquire the PhD degree; this discipline should preferably be one of the major foci of the program.
- certificates (4) On the basis of this application the PhD Committee shall decide on admission to PhD studies and determine the discipline in which the student can work for his or her PhD degree.
Chapter Three
PhD Committee
§ 4 PhD Committee (1) The PhD Committee appointed by the MHH senate shall be responsible for the conduct of PhD studies pursuant to the provisions relating to the Requirements and Rules for postgraduate studies and examinations to obtain a PhD (Dr.rer.nat.) degree. (2) The Committee shall be composed of four professors, a university scientist with a doctor’s degree, and a student in an advisory capacity. The members of the Committee shall be appointed by the MHH Senate for a period of four years, or two years as regards the student member. Re-election of the latter shall be admissible. The PhD students shall suggest a candidate from among their ranks. The Committee shall be constituted by the “Forschungsdekan” responsible for research and shall elect a professor from among its ranks as chairman. (3) The Committee will meet regularly, at least every 8 weeks. (4) The Committee will evaluate proposed projects (open projects) according to quality (with external referees if necessary), financial support, guarantee of independence for PhD student. (5) The PhD Committee shall appoint a team of co-ordinators for each PhD student. Such team shall be composed of the student’s personal co-ordinator (a scientist qualified as university teacher in the student’s specific field of research at the MHH), and two further scientists qualified as university teachers whose professional activity shall be closely related to the subject of the project. If no third MHH teacher can be found to join the team, a scientist qualified as university teacher in the student’s field of research but not actually teaching at university can be suggested to join the panel. In the presence of several PhD students doing research in the same line, the respective co-ordinators’ teams can be composed of the same individuals.
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Chapter Four Curriculum
§ 5 Contents of Studies
(1) The contents to be learned shall be conveyed to the students through their experimental or equivalent theoretical research work and through project-related as well as inter-disciplinary research-oriented courses and seminars. For that purpose, the PhD Committee shall prepare and submit, after consultation with the university institutions involved in these studies, a curriculum indicating compulsory and recommended courses or seminars for each discipline. The standard curricula will ensue from the model curriculum shown in Appendix 2 hereto. The courses and seminars shall be held by the teachers and professors of the MHH, the School of Veterinary Medicine, or the University of Hanover, including visiting professors. At least some of the teaching shall be in English. The curriculum may include courses and seminars held at a Graduiertenkolleg. PhD students may also register for suitable courses or seminars offered by other scientific schools (Hanover University, Hanover School of Veterinary Medicine, etc.). Students are encouraged to do active teaching themselves, e.g. by giving lectures at seminars or postgraduate research trainingprogram [Doktorandenkolleg]. Each student’s individual progress at PhD courses and seminars shall be monitored and consistently assessed by the respective teachers on the basis of tests, with teachers preparing written reports on the results obtained by the student. (2) PhD students shall design, after consultation concert with their co-ordinators, their respective individual schedules pursuant to the curriculum established by the PhD Committee. Such individual schedule shall require approval by the respective co-ordinators’ team. The student must complete a minimum of 300 hours at courses and seminars during his or her PhD studies; as a rule, at least 80% thereof must be taken at project-related courses and seminars and up to 20% may be spent on interdisciplinary learning (e.g. experimental techniques and bio-informatics, molecular biology, bio-statistics, scientific communication etc.). The European Credit Point System has been introduced for assessing tuition results.
During the first year of PhD studies, courses for physicians, dentists and veterinarians are intended to provide participants with a chance to consolidate their knowledge of the fundamental principles of natural sciences and courses for natural scientists are intended to consolidate their knowledge in medical aspects. (3) The structure of the PhD program and the modus of granting credit points (cp) according to the European ECTS system is as follows (accreditation according to European standards on December 9th, 2003). For the 3-year program altogether 180 cp have to be achieved:
- Every student will perform a 3-year research project in one of the departments of MHH or partner institutes. Altogether 125 cp are awarded.
- Every student will present his project including an open discussion annually within the department. All Co-supervisors are invited. Altogether 10 cp are awarded.
- For regular visits of and presentations in "Journal Clubs" 3 cp are awarded.
- Every student will present his project and discuss it within an annual public workshop. Before the workshop, a project report has to be handed in. Altogether 10 cp are awarded.
- For presentations (lecture or poster) on congresses/meetings maximal 2 cp are awarded.
- In the first year of study, students attend the obligatory seminars in Basics (2 SWS) and tutorial (1 SWS). At the beginning, specific in-depth seminars for medical students as well as life scientists (seperately) are offered. Altogether 8 cp are awarded.
- In the second year of study, students attend the obligatory advanced seminars with focus on research and applied aspects (2 SWS) and tutorial (1 SWS). Altogether 8 cp are awarded.
- Within 3 years, students will have to attend at least 80 hours of project-orientated seminars, including method courses and practical courses. Altogether 8 cp are awarded.
- Within 3 years, students will have to attend at least 60 hours of interdisciplinary seminars, including "soft skills" (presentation techniques, scientific writing etc.). Altogether 6 cp are awarded.
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PhD students could apply for a leave (e.g. in case of pregnancy), but for no more than 12 month. Short term stays abroad are very much appreciated and will be supported. If students take seminars and courses abroad, they could be acknowledged for the PhD program.
§ 6 Co-ordinators
(1) PhD students shall supervised by the members of their respective team of co-ordinators (§ 4) appointed by the PhD Committee. The responsibilities of the team shall be: a) To act as co-ordinators and to give individual expert advice to PhD students all through their PhD
studies while observing the MHH rules of proper scientific practice. b) To evaluate PhD students’ progress during their studies by reading their reports and conducting tests,
and to assess their written final examination papers. c) Within a time of probation of 6 months, PhD students are evaluated. Within this time peroid, student
status can be omitted easily in agreement with the supervisors and PhD Committee. Within the scope of their research project, students have to work with appropriate methods on a clearly defined subject so that, with some realistic prospect of success, scientific knowledge can be expected to be incremented and the results of such research should be published in international peer review journals. The co-ordinators shall make sure, and satisfy the PhD Committee to that effect, that students are not entrusted with any tasks unrelated to their PhD studies. Physicians registered for PhD studies shall be given an opportunity to do at least part of their pre-license internship (AIP). (2) The co-ordinators shall be responsible for the financing of the respective research project and shall make efforts, during the standard period of PhD studies (three years), to raise the money needed for the PhD students they are in charge of. Any scholarships available at the MHH, e.g. from internal sources such as the HiLF programme or from the Society of MHH Friends [Gesellschaft der Freunde der MHH], shall be awarded by resolution of the PhD Committee. (3) Co-ordinators should assist PhD students in planning their further professional career. (4) The responsibilities of co-ordinators for PhD students shall end upon the date when the latter pass their PhD examination (§ 10), which is normally three years but no later than five years after commencement of PhD studies.
§ 7 Scientific Colloquia PhD students shall be invited once every year by the PhD Committee to attend a public colloquium held at the MHH, giving them an opportunity to give a lecture on the current state of their research. The contents of such lecture, constituting an interim report, shall be submitted in writing by the PhD student to the PhD Committee. The Committee shall decide whether or not this progress report constitutes a sufficient step towards the successful completion of the student’s research. If the Committee’s comment is negative, such result shall be communicated in writing to the student and his or her co-ordinators’ team, indicating the reasons. Pursuant to a period of one month, the student shall submit a modified work plan for the next year of his research, giving due consideration to the recommendations made.
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Chapter Five
Examinations
§ 8 Intermediate Examination The oral intermediate examination shall be held no later than 18 months after commencement of PhD studies. By way of exception, which must be well-founded, the intermediate examination can be taken at a later date. If a student wishes such exception, he shall apply in writing to the PhD Committee adding a comment prepared by his co-ordinators’ team. The dates for intermediate examinations shall be determined by the PhD Committee. The intermediate examination shall be held by the a member of the PhD Committee and an expert (chairman) in the special field and shall cover topics from the student’s research project and from the courses and seminars the student has registered for. The examination usually is held in English. If the student fails the intermediate examination he shall be allowed to retake it once, pursuant to a period of at least three and no more than six months as the co-ordinators’ team may decide. If the student fails again, he or she shall be deemed to have finally and absolutely failed. Following such final and absolute failure the student shall be taken off the register. The “chairman” shall report the result of the intermediate examination to the PhD Committee. The result of the exam will account for 20% of the final mark (PhD or Dr.rer.nat.).
§ 9 Requirements for Signing up for PhD Examination After completion of PhD studies, which is normally at the end of the third year, the PhD examination shall be held by the co-ordinators’ team. The PhD student shall submit the following documents when signing up for the PhD examination: 1. Certificate of regular attendance at and completion of courses and seminars according to the
curriculum, i.e. a total of at least 300 hours (55 cp), and of two colloquia pursuant to § 7; 2. Certificate of intermediate examination; 3. A scientific thesis (dissertation) prepared in English or German by the PhD student on the research
project the student worked on during his or her PhD studies, with introduction, methodology, results, discussion and summary. The thesis shall constitute an essential original scientific contribution to the discipline the student’s research project pertains to;
4. Alternatively (instead of thesis), at least two first author publications in internationally renowned
peer review science journals. The PhD student’s personal contribution to such publications shall be clearly identified. In that context, “accepted” shall be deemed equivalent to “published”. As for this publication requirement, exceptions are possible with reasons to be given by the co-ordinator. The publications must be correlated as regards their subject matter, and shall be supplemented by a detailed description under a joint title in English or German of the research subject, including an overall summary and a discussion of results.
To assess the thesis or the publications, the PhD Committee shall procure at least one external
expert’s opinion. For the Dr. rer. nat., this expert has to be member of a natural science faculty. In addition, the co-ordinators’ team shall prepare an expert report on the dissertation or the publications, and such report together with the external expert’s opinion shall serve the PhD Committee to make their assessment. If one of the expert reports detects any shortcomings in the dissertation, the PhD Committee can be requested to have such shortcomings eliminated or remedied as a precondition for acceptance of the thesis. The chairperson can allow a reasonable period for the PhD candidate to remedy the shortcomings and recommend that he or she submit the thesis anew. In that respect, the chairperson of the PhD Committee can extend this period once only. The experts shall assess the thesis again once the shortcomings have been remedied. If, based on such second experts’ vote, the PhD Committee declines to accept the thesis, the candidate shall be deemed to have failed the PhD examination finally and absolutely. In that case, the PhD student shall be taken off the register.
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§ 10 PhD Examination The PhD examination consists of a public lecture (15 min, in English) held by the PhD student at the Medical School on the subject of his research, a subsequent public disputation of the project of at least 30 minutes of duration to assess the knowledge acquired by the student on the subject of his specific area of research as well as on interdisciplinary subjects. The interview also serves to assess whether the candidate has acquired, and is able to apply, any knowledge and skills relating to the scientific environment of the subject of his research. If the PhD student has opted for any minor subject not represented by the members of his or her co-ordinators’ team, the PhD Committee shall invite to the co-ordinators’ team a professor, or a scientific staff member who is qualified as a university teacher and lectures at the MHH, or an external scientist who in his or her own scientific research has dealt with the subject of the candidate’s research. Only the members of the co-ordinators’ team shall have a vote in deciding on the result of the examination. The assessment of the oral examination follows the Requirements and Rules for Examinations to Obtain a Doctor’s Degree in Natural Sciences set up jointly for the Departments of Natural Sciences at the University of Hanover. The oral examination shall be taken on record in abridged form and shall indicate:
the grade earned for the oral examination, the grade earned for the thesis, the overall grade average earned for the PhD examination.
It shall be signed by the chairman of the board of examiners. The following grades can be awarded: Excellent/ very good/ good / satisfactory / sufficient Equivalent to excellent / summa cum laude, very good / magna cum laude, good / laude, passed / rite. If the candidate fails the final examination he or she shall be allowed to retake it once, pursuant to a period of at least three and no more than six months as the co-ordinators’ team may decide. Should the student then fail again, he or she shall be deemed to have finally and absolutely failed the PhD examination. Following such final and absolute failure the student shall be taken off the register. The result of the PhD examination shall be communicated to the PhD Committee by the Rector’s office.
Chapter Six
The PhD Doctorate
§ 11 Award of the Academic Degree of a Doctor of Philosophy (PhD) Once the student has passed the PhD examination he or she shall be awarded the academic degree of a Doctor of Philosophy (PhD) or a Dr. rer. nat. degree by the MHH. A document as shown in Appendix 1 shall be issued to him or her in evidence of such award. The award shall authorize the candidate to use the academic title of a PhD, PhD or Dr. rer. nat..
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Coming into Effect Pursuant to § 80 sub-para. 1 NHG [Lower Saxon University Act], the foregoing provisions have been approved by the Ministry of Science and Culture (MWK) of the German Federal State of Lower Saxony by decree dated 30 May 2000 providing that a) the introduction shall be limited to an initial period of three years, b) the standard period of studies shall be three years, c) the academic degree of a “Doctor of Philosophy” (PhD) shall be awarded. The Requirements and Rules for Postgraduate Studies and Examinations to Obtain a PhD Degree, as approved by me, are hereby published within this Medical School. They shall come into effect the day after their publication in the official MHH gazette (“MHH-Info”). Hannover, February, 2004
The President Professor Dr. D. Bitter-Suermann
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