· Year Author Journal Title Product Category Products 1991 Science, Dec 1991; 254: 1669....

Year Author Journal TitleProductCategory Products

1991Science, Dec1991; 254: 1669.

Radioactive WastePlan Stalled

CustomOligo/DNA

......DNA for the study of virusesand patho-genic organisms,cytokines, growth factors, CDmarkers, genetic disorders, andmore. GeneMed Biotechnologies.Circle 341. LINKLINE is a newnewsletter from a company in the X-ray microanalysis field. Link Anal

1992 Buck GE

J. Clin.Microbiol., Dec1992; 30: 3280 -3283.

Rapid, sensitivedetection ofMycoplasmapneumoniae insimulated clinicalspecimens by DNAamplification.

CustomOligo/DNA

......both 24-bp fragments (MPN-101 and MPN-102) purchased fromGenemed Biotechnologies, Inc.,South San Francisco, Calif.Amplification...probe specific for thesegment being amplified (MPN-301;Genemed Biotechnologies).Hybridiza- tion was carried out

1993 See DM

Antimicrob.AgentsChemother., Aug1993; 37: 1593 -1598

WIN 54954treatment of miceinfected with adiabetogenic strainof group Bcoxsackievirus.

CustomOligo/DNA

......Oligonucleotide primers andprobes. The primers used for cDNAsynthesis and amplification bypolymerase chain reaction (PCR;Genemed, San Francisco, Calif.)were derived from a conservedsequence within a noncoding regionof the enterovirus genom

1993 Jaschek G

J. Clin.Microbiol., May1993; 31: 1209 -1212

Direct detection ofChlamydiatrachomatis in urinespecimens fromsymptomatic andasymptomatic menby using a rapid

CustomOligo/DNA dna

1994 Deng MY

Appl. Envir.Microbiol., ; 60:1927 - 1933

Detection ofhepatitis A virus inenvironmentalsamples by antigen-capture PCR.

CustomOligo/DNA

......of 0.4 mM, and 1.2 puM HAVprimer 2 (downstream primer)(Genemed Biotechnologies, Inc.,San Francisco, Calif.) wasadded...PCR buffer II, 1.2 p.m HAVprimer 1 (upstream primer)(Genemed), and 2.5 U of AmpliTaqDNA polymerase (Perkin-ElmerCetus.

List of Publications Using Genemed Synthesis Inc (GSI) Products and Custom Services (1992-2016);www.genemedsyn.com

1996 Wu L

J. Biol. Chem.,Dec 1996; 271:31202 - 31209

Discrete Steps inBinding andSignaling ofInterleukin-8 withIts Receptor

custompeptide

......using readings of relativefluorescence units. PeptideCompetition to the Antibody StainingPeptides were synthesized byGenemed Biotechnology (SanFrancisco, CA) and solubilized inphosphate-buffered saline. For thecompetition experiments, the an

1996 Doble BW

Circ. Res., Oct1996; 79: 647 -658.

Fibroblast GrowthFactor-2 DecreasesMetabolic Couplingand StimulatesPhosphorylation asWell as Masking ofConnexin43Epitopes in CardiacMyocytes

custompeptide

were obtained commercially fromImmunoDynamics Inc. A peptidecontaining residues 252 to 260(GPLSPSKDC) was purchased fromGenemed Biotechnologies, Inc.These peptides were used at 0.01mg/mL final concentration inantibody-blocking experiments.Protein

1996 Miller JLPNAS, Apr 1996;93: 3565 - 3569.

Mimotope/anti-mimotope probingof structuralrelationships inplatelet glycoproteinIb

custompeptide

......peptide with Gly -> Val atresidue 9. Lyophilized peptides(Genemed Biotechnologies) werereconstituted in PBS (pH 6.0)and...Woodlands, TX). All otherpeptides were purchased fromGenemed Bio- technologies (SouthSan Francisco, CA). RESULTSDevelo

1997 Xu D-L

J. Clin. Invest.,Apr 1997; 99:1500 - 1505

Upregulation ofAquaporin-2 WaterChannelExpression in

customantipeptideantibodies cab

1997WeeraratnaAT

Clin. CancerRes., Dec 1997;3: 2295 - 2300

Loss of uteroglobinexpression inprostate cancer:relationship toadvancing grade

CustomOligo/DNA

with hematoxylin. AntibodyPreparation. A peptide comprised ofthe 20 amino acid residues 37-56 ofhuman UG was synthesized byGenemed (San Francisco, CA). Thispeptide was conjugated to keyholelimpet hemocyanin and used toraise antibody in rabbits by t

1997 Rong H

Clin. Chem., Dec1997; 43: 2268 -2273

Quantification ofparathyroidhormone-relatedprotein mRNA bycompetitive PCRand time-resolvedlanthanidefluorometry

CustomOligo/DNA

......target DNA (T-probe) and theother recognizing the competitor (C-probe). Custom oligonucleotidesynthesis was performed byGenemed Biotechnologies with anAmino Linker C3 at the 5-end.HPLC-purified oligonucleotides weredissolved in distilled wate

1997 Santy LC

Am J PhysiolEndocrinolMetab, Dec1997; 273:E1140 - E1148

Expression of asingle geneproduces bothforms of skeletalmuscle cyclicnucleotide-gatedchannels

CustomOligo/DNA

Harvard University, Cambridge,MA). Lipids were purchased fromAvanti Polar Lipids (Alabaster, AL).Primers were ordered fromGenemed Biotechnologies (SouthSan Francisco, CA). RNA isolationand cDNA production. Total RNAwas isolated from rabbit tissues

1997 Ciorba MA

PNAS, Sep1997; 94: 9932 -9937

Modulation ofpotassium channelfunction bymethionineoxidation andreduction

CustomOligo/DNA

......and the Met(O)-containingShCB peptide Met-Glu-Met(O)-ILe-Leu-Val-Ala-Gly-Gly-Ser-Leu-Pro-Lys-Leu-Ser-Ser were obtained fromGenemed Biotechnologies, SouthSan Francisco, CA (85 pure). (B)Preincubation of the Met(O)-containing ShCB peptide with Ms

1997 García SI

Hypertension,Sep 1997; 30:759 - 766.

CentralOverexpression ofthe TRH PrecursorGene InducesHypertension inRats : AntisenseReversal

CustomOligo/DNA

......of the transcript that is codifiedby the bGH polyadenylation signal ofthe pcDNA3 vector (5 GGA GGGGCA AAC AAC AGA TG 3;Genemed Biotechnologies). PCRproduct was identified by Southernblotting using the above-mentionedpre-TRH cDNA probe. Dienc

1997WoodwardRN

Mol. Endocrinol.,May 1997; 11:563 - 576

Novel AccessoryFactor-Binding SiteRequired forGlucocorticoidRegulation of the -Fibrinogen SubunitGene fromXenopus laevis

CustomOligo/DNA

oligonucleotides for PCR wereobtained either from the MolecularBiology Program DNA Core Facilityat the University of Missouri or fromGenemed Biotechnologies (SanFrancisco, CA). Standard conditionsof 10 Mm primers, 4 ng template,and 2 mm MgSO4 in an

1997 Perry LL

J. Immunol., Apr1997; 158: 3344 - 3352

Immunity toChlamydiatrachomatis ismediated by Thelper 1 cellsthrough IFN-gamma-dependentand -independentpathways

CustomOligo/DNA

......using the Gene Runnerprogram (Hastings Software,Hastings, NY) based upon GenBankaccession M64239 and wassynthesized by GeneMed (SanFrancisco, CA). &Chain primersequences yielding a 240-bpproduct were as follows:GCTTGGTCAGTATGGAGATTCG(sense

1997 Gorny MK

J. Immunol., Nov1997; 159: 5114 - 5122

Human monoclonalantibodies to the V3loop of HIV-1 withintra- and intercladecross-reactivity

custompeptide

......Cambridge, MA): one peptideMN was synthesized by PeninsulaLaboratories (Belmont, CA): andpeptide SF1703 was synthesized byGenemed Biotechnologies, Inc.(South San Francisco, CA).According to the manufacturers'information, peptides were analyz

1997 Zhao S

J. Biol. Chem.,Nov 1997; 272:28368 - 28372

A ProteinPhosphatase-1-binding MotifIdentified by thePanning of aRandom PeptideDisplay Library

custompeptide

CGPSTRHVHWDDREAGPC, andCGPRVSRHVHWADLEGPC weresynthesized by GENEMEDSynthesis Inc. (South SanFrancisco, CA). Thepeptides...CGPSTRHVHWDDREAGPC), and D2(CGPRVSRHVHWADLEGPC) weresynthesized by GENEMEDSynthesis Inc. Peptides weredissolved in water an

1997 Bolin LM

J. Neurosci., Jul1997; 17: 5493 -5502

HNMP-1: A NovelHematopoietic andNeural MembraneProteinDifferentiallyRegulated in NeuralDevelopment andInjury

custompeptide

......HTEEILAKHPSGG conjugatedto KLH) encoding the putativesecond extracellular loop of mouseHNMP-1 was the immunogen forrabbit antisera (GenemedBiotechnologies, South SanFrancisco, CA). Specific IgG wasaffinity-purified against the syntheticpept

1997 Yan C

J. Biol. Chem.,Jul 1997; 272:17327 - 17332

Protein Kinase AActivation of theSurfactant ProteinB Gene Is Mediatedby Phosphorylationof ThyroidTranscriptionFactor 1

custompeptide

protein (1 Mg), TTF-1 homeodomainpolypeptide (1 Mg) obtained fromDr. DiLauro, or synthetic TTF-1peptides (30 Mg) made byGenemed Inc. (San Francisco),were incubated with 1 Ml (22 units)of purified PKA catalytic subunit(Calbiochem) in the presence of

1997 Han L

PNAS, May1997; 94: 4954 -4959.

Protein binding andsignaling propertiesof RIN1 suggest aunique effectorfunction

custompeptide

purified on glutathione-Sepharose(Pharmacia), dialyzed with PBS, andconcentrated. The peptideKSSPLSPPAVPPPPVPVLPGARRASLG (Genemed Biotechnologies,South San Francisco, CA) containsthe putative SH3 binding site(underlined), five flanking RIN1residues

1997 Brown RL

Stem Cells, May1997; 15: 237 -245

Serum-FreeCulture Conditionsfor Cells Capable ofProducing Long-Term Survival inLethally IrradiatedMice

custompeptide

......ng) to 100% (2 mug). Totalmurine chromosomal DNA wasevaluated using the BAC-202murine beta-actin oligonucleotideprobe (Genemed BiotechnologiesInc.; San Francisco, CA) 3-endlabeled with digoxigenin (GeniusOligonucleotide 3-End Labeling Kit,B

1997 Zaheer A

J. Biol. Chem.,Feb 1997; 272:5183 - 5186

Protein Kinase A(PKA)- and ProteinKinase C-phosphorylatedGlia MaturationFactor Promotesthe CatalyticActivity of PKA

custompeptide

......32P]ATP (3000Ci/mmol) waspurchased from DuPont NEN. GMFpeptides for phosphorylationexperiments were customsynthesized by Genemed Biotech(South San Francisco, CA), exceptpeptides I and IV, which were giftsof R.A.Copelend of DuPont MerckPharm

1997 Yu J

J. Exp. Med.,Feb 1997; 185:745 - 754

Mapping the ActiveSite of CD59

custompeptide

......mature CD59(CKKDLCNFNEQLE) and wasconjugated to KLH for immunization.Peptide synthesis and KLHconjugation was performed byGenemed (South San Francisco,CA). Anti-CD59 peptide Ab wasaffinity purified by means of peptideimmobilized onto CNBr-a

1998 Fewell JG

J. Clin. Invest.,Jun 1998; 101:2630 - 2639

FunctionalSignificance ofCardiac MyosinEssential LightChain IsoformSwitching inTransgenic Mice

customantipeptideantibodies

......Miles Laboratories, Inc.,Elkhart, IN). Sections (5 or 7 mum)were incubated with rabbitpolyclonal antisera against ELC1a(Genemed Biotechnologies, Inc.,San Francisco, CA), and with amonoclonal antibody against alpha-actinin ( Sigma Chemical Co.

1998 Shaw G-C

J. Biol. Chem.,Apr 1998; 273:7996 - 8002.

Evidence againstthe Bm1P1 Proteinas a PositiveTranscriptionFactor forBarbiturate-mediated Inductionof CytochromeP450BM-1 inBacillus megaterium


Sequenase version 2.0 DNAsequencing kit were fromAmersham Pharmacia Biotech.Oligonucleotides used in PCR wereordered from Genemed Synthesis,Inc. BCA protein assay kit was fromPierce. Rabbit polyclonal antibodiesagainst cytochrome P450BM-1 wereprep

1998 Zhou B-Y

J. Gen. Physiol.,Apr 1998; 111:555 - 563.

Specific Antibodiesto the ExternalVestibule ofVoltage-gatedPotassiumChannels BlockCurrent


......2-BA, Kv1-NA, and Kv3.1-BArabbit polyclonal antibodies weremade and affinity purified through acontracted manufacturer (GenemedBiotechnologies, Inc., South SanFrancisco, CA). A cysteine residuewas added to the carboxyl end ofthe peptide FAEA

1998 Ohara M

J. Clin. Invest.,Mar 1998; 101:1076 - 1083

Upregulation ofAquaporin 2 WaterChannelExpression inPregnant Rats


with the mean value in controls(100%). Western blot analysis Therabbit polyclonal antibody againstAQP2 was prepared by GenemedBiotechnologies, Inc. (South SanFrancisco, CA) using a syntheticpeptide (CELHSPQSLPRGSKA)from the carboxy terminus of AQP2

1998 Dong F

Mol. Biol. Cell,Aug 1998; 9:2081 - 2092

Cyclin D3-associated KinaseActivity IsRegulated byp27kip1 in BALB/c3T3 Cells

CustomOligo/DNA

......the pRb sequence andpreviously demonstrated to reflectcdk4 phosphorylation sites weresynthesized and purified by HPLC atGenemed Synthesis (South SanFrancisco, CA). The nomenclatureutilized in this report corresponds tothat previously reporte

1998 Shapira H

J. Biol. Chem.,Jul 1998; 273:19431 - 19436

G 14 and G qMediate theResponse toTrypsin in XenopusOocytes

CustomOligo/DNA

......inhibitor, goat anti-rabbit IgG,and ACh were purchased fromSigma; GRP14-27 from Bachem, S-oligos from Oligos Etc.; primersfrom Genemed Biotechnologies;and radiodeoxynucleotides fromNEN Life Science Products. Allmolecular biology reagents were

1998 Lu D

J. Cell Biol., Jul1998; 142: 217 -227

Regulation ofAngiotensin II-inducedNeuromodulationby MARCKS inBrain Neurons

CustomOligo/DNA

......serines at positions 151, 155,159, and 162, were replaced byalanine (KRFAFKKAFKLAGFAFKK;mut148-165) were synthesized byGenemed Biotechnologies (SanFrancisco, CA). Pep148-165competes for PKC-mediatedphosphorylation of MARCKS sincethree out o

1998RichardsOC

J. Biol. Chem.,May 1998; 273:12832 - 12840

Effects of Poliovirus3AB Protein on 3DPolymerase-catalyzed Reaction

CustomOligo/DNA

were from Boehringer Mannheim.Isopropyl b-d-thiogalactopyranosidewas obtained from Sigma. DNAprimers were synthesized byGenemed Biotechnologies, Inc.Escherichia coli JM110 wasprovided by Bert Semler, Universityof California, Irvine. E. coli BL21(DE

1998 Deng MQ

Appl. Envir.Microbiol., May1998; 64: 1954 -1957

Differentiation ofCryptosporidiumparvum Isolates bya SimplifiedRandomlyAmplifiedPolymorphic DNATechnique

CustomOligo/DNA

Figure illustrates the resultsobtained with primers GPD62(CAATGCCCGA; GeneMedBiotechnologies, San Francisco,Calif.) (lanes 1 to 4) and GPD63(CAATGCCCGA, GeneMed) (lane 5to 8). Both primers producedmultiple bands, usually rangingfrom......

1998 Bennett RJ

J. Biol. Chem.,Apr 1998; 273:9644 - 9650

Purification andCharacterization ofthe Sgs1 DNAHelicase Activity ofSaccharomycescerevisiae

CustomOligo/DNA

albumin solutions as standards, wasbetween 1 and 2.5 mg for severalpreparations. Nucleic AcidSubstrates DNA oligomers(GENEMED) were purified bypolyacrylamide gel electrophoresiswhen necessary. The RNA oligomerwas purchased from DaltonChemical Labo

1998 Li M

J. Biol. Chem.,Apr 1998; 273:9790 - 9796

Analysis of theDNA-binding Sitefor XenopusGlucocorticoidReceptorAccessory Factor.CRITICALNUCLEOTIDESFOR BINDINGSPECIFICITY INVITRO AND FOR

CustomOligo/DNA

the XGRAF region had beenmutated. The upstream primer, 5-GGGGTACCAGACAGAAAAGAGTTAATGTTCCCTCTTATGTTC-3, wassynthesized (GenemedBiotechnologies, Inc.) in a singlereaction, with the reservoir for eachnucleotide in the potential bindingsite (underline

1998 Li Y

J. Biol. Chem.,Apr 1998; 273:9959 - 9965.

Involvement of Sp1Elements in thePromoter Activity ofthe 1-ProteinaseInhibitor Gene

CustomOligo/DNA

......Primer sequences were asfollows: Gsp1,GTAGACTTCGGGTGGAGGCAGT;and Gsp2,GGGGAGCTTGGACAGGAAG.Primers were synthesized byGenemed Biotechnologies, Inc.(South San Francisco, CA).Methods PromoterFinder, Cloning,and Sequencing The PromoterFinder

1998 Lu D

J. Neurosci., Feb1998; 18: 1329 -1336

Involvement of p62Nucleoporin inAngiotensin II-Induced NuclearTranslocation ofSTAT3 in BrainNeurons

CustomOligo/DNA

......amino acid sequence of 189 to198 (GSPFTPATLA) and its mutantwhere the Thr193 was substitutedwith Ala were synthesized byGenemed Biotechnologies (SanFrancisco, CA). All otherbiochemicals were from FisherScientific (Pittsburgh, PA) and wereof

1998 Montani V

Endocrinology,Jan 1998; 139:280 - 289.

MajorHistocompatibilityClass II HLA-DRGene Expression inThyrocytes:Counter Regulationby the Class IITransactivator andthe Thyroid Y Box

CustomOligo/DNA

......Operon Technologies, Inc.,Alameda, CA) or were purified from2% agarose gel using QIAEX(Qiagen, Chatsworth, CA) or Jet-Sorb (Genemed, Frederick, MD),following restriction enzymetreatment of the chimeric class IICAT constructs. They were labele

1998 Burke DH

Chemistry &Biology, Volume4, Issue 11,November 1997,Pages 833-843

RNA aptamers tothe peptidyltransferase inhibitorchloramphenicol

CustomOligo/DNA

Mutagenized pools weresynthesized as bottom strand byGenemed Synthesis to yield aparticular DNA template

1998 Lohnas GL

J. Immunol., Dec1998; 161: 6518 - 6525

Epitope-SpecificAntibody andSuppression ofAutoantibodyResponses Againsta Hybrid SelfProtein

custompeptide

sequences of UbV3 were obtainedin 70-90% purity by conventionalautomated solid phase synthesisthrough a commercial service(Genemed Synthesis, South SanFransisco, CA). Synthetic peptideKRIHIGPGRAFYTTK (V3) wasobtained through the AIDSResearch and R

1998 Yan J

J. Neurosci., Nov1998; 18: 8682 -8691

Purification fromBovine Serum of aSurvival-PromotingFactor for CulturedCentral Neuronsand ItsIdentification asSelenoprotein-P

custompeptide

coupling of the peptide to a carrierprotein (hemocyanin). Theimmunogen (peptide linked tocarrier) was injected into rabbits(Genemed Biotechnologies, SouthSan Francisco, CA). Antibodieswere affinity-purified with the peptideimmobilized on agarose re

1998 Horowitz A

J. Biol. Chem.,Oct 1998; 273:25548 - 25551

Phosphorylation ofthe CytoplasmicTail of Syndecan-4RegulatesActivation ofProtein Kinase C

custompeptide

......Boston, MA). A 28-amino acid-long syndecan-4 cytoplasmic tailpeptide (S4c)(RMKKKDEGSYDLGKKPIYKKAPTNEFYA) was synthesized byGenemed Synthesis (South SanFrancisco, CA). A similar peptidewith a phosphorylated Ser (S4c-P)was synthesized by the Bi

1998CampbellPG

Am J PhysiolEndocrinolMetab, Aug1998; 275: E321 - E331.

Plasminogen bindsthe heparin-bindingdomain of insulin-like growth factor-binding protein-3

custompeptide

......kindly provided by Dr. DennisAndress (Univ. of Washington,Seattle, WA). The IGFBP-3 HBDpeptide (Table ) was synthesized byGenemed Synthesis (South SanFrancisco, CA). Human serum andplasma were obtained fromoutdated blood bank supplies or fro

1998 Calero G

Circ. Res., May1998; 82: 929 -935

A 17mer PeptideInterferes WithAcidification-Induced Uncouplingof Connexin43

custompeptide

......production of the 17mer peptidehas been described before. 22Other short peptides werepurchased from a commercialsupplier (Genemed Inc). All peptideswere assessed chromatographicallyand determined to be 95% pure. Apolypeptide of the CT domain

1998 Ettinger RA

J. Immunol., Mar1998; 160: 2365 - 2373

A Peptide BindingMotif for HLA-DQA1*0102/DQB1*0602, the Class IIMHC MoleculeAssociated withDominantProtection in Insulin-DependentDiabetes Mellitus

custompeptide

......Peptide Synthesizer (FosterCity, CA) or purchased fromGeneMed Synthesis, Inc. (SouthSan Francisco, CA). Peptideswere...spectrometry was performedby Anaspec, Inc. (San Jose, CA),GeneMed Synthesis, Inc., and theProtein and Carbohydrate Structu

1998 Lu D


Angiotensin II-Induced NuclearTargeting of theAngiotensin Type 1(AT1) Receptor inBrain Neurons

custompeptide

......PLUS-agarose was purchasedfrom Santa Cruz Biotechnology.Genemed Biotechnologies, Inc.(San Francisco, CA) providedsynthetic...p62-mut), weresynthesized. All peptides weresynthesized by GenemedBiotechnologies Inc. This regioncontained the con

1998 Zundel CJ

FEBS Letters,Volume 441,Issue 2, 18December 1998,

Analysis of theconserved acidicresidues in theregulatory domain

custompeptide mutagenic primers

1998 Toroser D

FEBS Letters,Volume 435,Issue 1, 11September 1998,Pages 110-114

Site-specificregulatoryinteraction betweenspinach leafsucrose-phosphate

custompeptide

SPS-229 peptide(CRVDLLTRQVpSAPGVDK)

1998 Tu T-Y

HearingResearch,Volume 123,Issues 1-2,September 1998,Pages 97-110

Establishment andcharacterization ofa strial marginal cellline maintainingvectorial electrolytetransport

custompeptide

25-mer, extendingfrom nucleotide (nt) 253 to 277, 5P-ATGCATAGTATATAGAGATGGGAAT-3

1998Cruickshank KA

Journal ofChromatographyA, Volume 817,Issues 1-2, 21August 1998,

Simultaneousmultiple analytedetection usingfluorescentpeptides and

custompeptide

cysteine and lysine containingpeptides

1999 Piros ET

J. Biol. Chem.,Nov 1999; 274:33677 - 33683

Purification of anEH Domain-bindingProtein from RatBrain ThatModulates theGating of the Ratether-à-go-goChannel


......and enhancedchemiluminescence detection (NENLife Science Products Inc.). Anaffinity purified rabbit anti-EAGantibody (Genemed Synthesis),raised against an EAG peptide(NGSGSGKWEGGPSKNS), wasused to immunoprecipitate EAGfrom transfected 293 c

1999 He CL

Biol Reprod, Oct1999; 61: 935 -943.

Isoforms of theInositol 1,4,5-TrisphosphateReceptor AreExpressed inBovine Oocytesand Ovaries: TheType-1 Isoform IsDown-Regulated by


......peptide used to raise theantibody (a generous gift of Dr.Frank Longo, University of Iowa,Iowa City, IA, and prepared byGenemed Biotechnologies Inc.,South San Francisco, CA) beforedilution to 1:200 for probing themembrane. Statistical Analysi

1999 Liu X

J. Biol. Chem.,Oct 1999; 274:28674 - 28681

Rat B2 SequencesAre Induced in theHippocampal CA1Region AfterTransient GlobalCerebral Ischemia


......custom-synthesized byGenosys Corp. (The Woodlands,Texas). Peptide synthesis and rabbitantibody production was provided byGenemed Synthesis, Inc. (SouthSan Francisco, CA). Total RNAIsolation Total RNA was isolatedfrom eight 4VO - and eight sh

1999 Guo L

J. Biol. Chem.,Apr 1999; 274:9836 - 9842

Photorhabdusluminescens W-14Insecticidal ActivityConsists of at LeastTwo Similar butDistinct Proteins.PURIFICATIONANDCHARACTERIZATION OF TOXIN AAND TOXIN B


......peptide A2), andFDSYSQLYEENINAGEQRA(peptide B2). The correspondingantibodies to the above threepeptides were generated inGenemed Biotechnology Inc. (SanFrancisco, CA). The crude serawere purified using a SulfoLinkTMCoupling Gel column (Pier

1999 Wang R

Am J PhysiolLung Cell MolPhysiol, Dec1999; 277: 1245 - 1250

Fas-inducedapoptosis ofalveolar epithelialcells requires ANGII generation andreceptor interaction.

CustomOligo/DNA

......saralasin, and antibodies toANG II and ANGEN were obtainedfrom Sigma (St. Louis, MO). Primersfor RT-PCR were synthesized byGenemed Synthesis (SanFrancisco, CA). Lipofectin reagent(Oligofectin G) was obtained fromSequitur (Natick, MA). All ot

1999 Wilson HL

J. Bacteriol., Sep1999; 181: 5814 - 5824

Halophilic 20SProteasomes of theArchaeonHaloferax volcanii:Purification,Characterization,and GeneSequence Analysis

CustomOligo/DNA

from New England Biolabs (Beverly,Mass.) or Promega (Madison, Wis.)unless otherwise indicated.Oligonucleotides were fromGenemed Synthesis (SanFrancisco, Calif.). Digoxigenin-11-dUTP (2-deoxyuridine-5-triphosphate coupled by an 11-atomspacer to digox

1999 Shih S-C

J. Biol. Chem.,May 1999; 274:15407 - 15414

Role of ProteinKinase C Isoformsin Phorbol Ester-induced VascularEndothelial GrowthFactor Expressionin HumanGlioblastoma Cells

CustomOligo/DNA

......of the antisense PKColigonucleotides to PKC-a, -b, -, -, -e, and -z were synthesized asphosphorothioate derivatives fromGenemed Synthesis (SanFrancisco, CA). Seven differentkinase inhibitors were used andpurchased from Calbiochem asfollows:

1999 Baranski TJ

J. Biol. Chem.,May 1999; 274:15757 - 15765

C5a ReceptorActivation.GENETICIDENTIFICATIONOF CRITICALRESIDUES INFOURTRANSMEMBRANE HELICES

CustomOligo/DNA

......PstI was subcloned into the C5areceptor DNA containing silent SphIand PstI sites. The followingoligonucleotides were used(Genemed, S. San Francisco, CA;underlines denote bases doped with20 nonwild-type nucleotides): HelixIII, 5-CCCGCATGCTCTA

1999 Wang R

Am J PhysiolLung Cell MolPhysiol, May1999; 276: 885 -889

Angiotensin IIinduces apoptosisin human and ratalveolar epithelialcells

CustomOligo/DNA

......Louis, MO). Fluorescein-conjugated annexin V was obtainedfrom PharMingen (San Diego, CA),and PCR primers were synthesizedby Genemed Synthesis (SanFrancisco, CA). All other materialswere from sources described earlier(, ) or were of reagent gr

1999ChausseeMS

Infect. Immun.,Apr 1999; 67:1715 - 1722.

The rgg Gene ofStreptococcuspyogenes NZ131PositivelyInfluencesExtracellular SPE BProduction

CustomOligo/DNA

and Rgg-R (5-ATCGCCCTGGAGCTGTTGAG-3),were synthesized by GenemedBiotechnologies, Inc. (SanFrancisco, Calif.). Rgg-Fcorresponded...determined by usingcustom-designed oligonucleotideprimers (Genemed Synthesis) and aDye Terminator Cycle SequencingRea

1999 Farrell DJ

J. Clin.Microbiol., Mar1999; 37: 606 -610.

Nested DuplexPCR To DetectBordetella pertussisand Bordetellaparapertussis andIts Application inDiagnosis ofPertussis inNonmetropolitanSoutheast

CustomOligo/DNA

......three suppliers: Bresatech(Adelaide, South Australia), Gibco-Life Technologies (Gaithersburg,Md.), and Operon Technologies orGenemed Technologies (both inSan Francisco, Calif.;oligonucleotides were purchasedfrom Fisher-Biotech, Perth, Austral

1999 Shih S-C

J. Biol. Chem.,Jan 1999; 274:1359 - 1365

Regulation ofHuman VascularEndothelial GrowthFactor mRNAStability in Hypoxiaby HeterogeneousNuclearRibonucleoprotein L

CustomOligo/DNA

......University Pennsylvania,Philadelphia) (, ). All of theoligodeoxyribonucleotides used inthe study were synthesized fromGenemed Synthesis (SanFrancisco, CA). Cell Lines andCulture Conditions Humanmelanoma cell line M21 wasobtained from Dr. Ro

1999 Han Y

J. Biol. Chem.,Jan 1999; 274:939 - 947

Interleukin-1-induced NuclearFactor- B-I BAutoregulatoryFeedback Loop inHepatocytes. AROLE FORPROTEIN KINASEC IN POST-TRANSCRIPTIONAL REGULATION

CustomOligo/DNA

......oligodeoxynucleotide (ODN,sequence 5-GTTCTCGCTGGTGAGTTTCA -3)and scrambled version (5-GGTTTTACCATCGGTTCTGG-3obtained from GenemedBiotechnologies, South SanFrancisco, CA) were introduced intoHepG2 cells as described (). Whereindicated, transi

1999 Ho Y-D

J. Biol. Chem.,Jan 1999; 274:464 - 470

IQGAP1 IntegratesCa2+/Calmodulinand Cdc42Signaling

CustomOligo/DNA

......fragment) were purchased fromNew England Biolabs, Inc.Nucleotide primers for polymerasechain reaction were obtained fromGenemed Biotechnologies.Radionucleotides were fromDuPont. Calmodulin-Sepharose waspurchased from Pharmacia BiotechInc. G

1999 Alzerreca JJ

FEMSMicrobiologyLetters, Volume180, Issue 1, 1

The amo operon inmarine, ammonia-oxidizing γ-proteobacteria

CustomOligo/DNA

Primers were preparedcommercially (Genemed Synthesis

1999 Fong LG

J. Biol. Chem.,Dec 1999; 274:36808 - 36816

The Processing ofLigands by theClass A ScavengerReceptor IsDependent onSignal InformationLocated in theCytoplasmicDomain

custompeptide

......1 cells were obtained fromAmerican Type Culture Collection(Manassas, VA). Syntheticoligonucleotides were purchasedfrom Genemed Biotechnologies(South San Francisco, CA) orGenosys (Woodlands, TX).Lipoproteins Human LDL (d 1.019-1.063 g/ml) was

1999 Pan PK-Y

Eur. J. Biochem.,Nov 1999; 266:33 - 39

Why reversing thesequence of thedomain of humanmetallothionein-2does not change itsmetal-binding andfoldingcharacteristics

custompeptide

......adomain (residues 31-61), thebdomain (residues 1-30), and theretro-adomain of human liver MT-2,respectively, were synthesized(Genemed Synthesis). The sidechains of Cys residues of thesynthetic peptides were protected byacrylamide protecting

1999 Tseng C-P

J. Biol. Chem.,Nov 1999; 274:31981 - 31986

The Role of DOC-2/DAB2 ProteinPhosphorylation inthe Inhibition of AP-1 Activity. ANUNDERLYINGMECHANISM OFITS TUMOR-SUPPRESSIVEFUNCTION INPROSTATE

custompeptide

......described previously (). TheSer24 peptide(APS24KKEKKKGSEKTD) and theAla24 peptide(APA24KKEKKKGSEKTD) weresynthesized by GenemedBiotechnologies, Inc. (SanFrancisco, CA). Cell Cultures COS,NbE, and C4-2 cells weremaintained in T medium suppl

1999 Marino M

J. Biol. Chem.,Oct 1999; 274:30377 - 30386

Identification of aHeparin-bindingRegion of RatThyroglobulinInvolved in MegalinBinding

custompeptide

sequence () (SRRLKRP) wassynthesized by GenemedBiotechnologies (South SanFrancisco...with Tg peptide 1 thepreparation from GenemedBiotechnologies was used. Another15-amino...substituted with glycinewas synthesized by GenemedBiotechnologies and was

1999Martínez-Senac MDM

Eur. J. Biochem.,Oct 1999; 265:744 - 753

Structure of theAlzheimer -amyloidpeptide (25–35)and its interactionwith negativelychargedphospholipidvesicles

custompeptide

......Lipids, Inc. (Birmingham, AL,USA) and dissolved inchloroformmethanol (1:1, vv). ThebAP(25-35) peptide was purchasedfrom Genemed Synthesis, Inc. (SanFrancisco, CA, USA). D2O wasobtained from Sigma Chemicals Co.(Madrid, Spain) and all solvents

1999CampbellPG

J. Biol. Chem.,Oct 1999; 274:30215 - 30221

Insulin-like GrowthFactor-bindingProtein-3 BindsFibrinogen andFibrin

custompeptide

......Bend, IN). Peptide IGFBP-3hbd(KKGFYKKKQCRPSKGRKR),which encodes the heparin bindingdomain of IGFBP-3 (), wassynthesized by Genemed Synthesis,Inc. (South San Francisco, CA). Glu-Pg was purified as describedpreviously (). Plasmin ( Pm ) was obt

1999 Xu Y

Antimicrob.AgentsChemother., Sep1999; 43: 2256 -2262

Histatin 3-MediatedKilling of Candidaalbicans: Effect ofExtracellular SaltConcentration onBinding andInternalization

custompeptide

binding of histatin to the plasmamembrane. MATERIALS ANDMETHODS Labeling of histatin 3.Histatin 3 was synthesized byGeneMed Synthesis, Inc. (SanFrancisco, Calif.), and purified byhigh-pressure liquidchromatography. Composition of theprotein was...

1999 Subklewe MBlood, Aug 1999;94: 1372 - 1381

Induction of Epstein-Barr Virus-SpecificCytotoxic T-LymphocyteResponses UsingDendritic CellsPulsed With EBNA-3A Peptides or UV-Inactivated,Recombinant

custompeptide

FLRGRAYGL and QAKWRLQTL,were purchased from Biosynthesis(Lewisville, TX). The EBNA-3Apeptide FLRGRAYGI waspurchased from GenemedSynthesis (San Francisco, CA). Allpeptides were greater than 95 pureby mass spectrometry and high-performance liquid chr

1999ResendesMC

J. Biol. Chem.,Jul 1999; 274:19417 - 19421

NuclearLocalization of the82-kDa Form ofHuman CholineAcetyltransferase

custompeptide

......terminus of human ChATprotein (CEKATRPSQGHQP) ()conjugated to maleimide-activatedkeyhole limpet hemocyanin asimmunogen (Genemed SynthesisInc.). ChAT-specificimmunoglobulins were affinity-purified on a column of the ChATcarboxyl-terminal pept

1999 Liu RY

J. Biol. Chem.,May 1999; 274:13877 - 13885

Tumor NecrosisFactor- -inducedProliferation ofHuman Mo7eLeukemic CellsOccurs viaActivation ofNuclear Factor BTranscription Factor

custompeptide

......factor and the mutant nucleartranslocation motif of human NF-kBp50 (). Both SN50 and SN50mtwere synthesized commercially(Genemed Synthesis, South SanFrancisco, CA). The peptides werepurified by reverse phase highperformance liquid chromatogr

1999Zolla-Pazner S

J. Virol., May1999; 73: 4042 -4051.

Immunotyping ofHumanImmunodeficiencyVirus Type 1 (HIV):an Approach toImmunologicClassification of HIV

custompeptide

purity of 80. All peptides fromIntracel contained cysteine residuesat the N terminus. One peptide,D687, was synthesized byGenemed Biotechnologies, Inc.(South San Francisco, Calif.); it wassynthesized by using the standard 9-fluorenylmethoxycarbonyl

1999 Rossi DL

J. Immunol., May1999; 162: 5490 - 5497

Lungkine, a NovelCXC Chemokine,SpecificallyExpressed by LungBronchoepithelialCells

custompeptide

the Lungkine peptideCLDPDAPWVKATVGPITNRFLPEDLKQKE-COOH (Genemed, SouthSan Francisco, CA). The negativecontrols used in...methods (14).Rabbit polyclonal affinity-purifiedantiserum (Genemed, South SanFrancisco, CA) was used as theprimary Ab for…

1999 Zhang H-F

J. Biol. Chem.,Apr 1999; 274:10969 - 10974

Identification of theIndividual ResiduesThat DetermineHuman CD59Species SelectiveActivity

custompeptide

......Diego, CA). Four CD59sequence specific peptides weresynthesized and high pressure liquidchromatography-purified (80) byGenemed (South San Francisco,CA); peptide 1, RLRENELTY;peptide 2, FNDVTTRLRENELTY;peptide 3,WKFEHCNFNDVTTRLRENELTY;and p

1999 Wallner M

PNAS, Mar1999; 96: 4137 -4142

Molecular basis offast inactivation involtage and Ca2+-activated K+channels: Atransmembrane -subunit homolog

custompeptide

......by using the overlap extensionmethod (). b2 ball peptidesconsisting of 19 or 26 N-terminalamino acids were synthesized(Genemed Biotechnologies, SouthSan Francisco, CA). The peptideswere dissolved to a concentration of10 mM in 50 mM TrisCl an

1999 Gu C

J. Biol. Chem.,Mar 1999; 274:8012 - 8021

Calmodulin-bindingSites on AdenylylCyclase Type VIII

custompeptide

......Chou and Fasman program.Two peptides were synthesized(Genemed Synthesis Inc., SouthSan Francisco, CA). One was 21residues...liquid chromatographyand mass spectroscopy,respectively (Genemed Synthesis).The peptide (CamkII,LKKFQARRKLKGAILTTMLA

1999 Lou L

Mol. Pharmacol.,Mar 1999; 55:557 - 563

Modulation ofCa2+/Calmodulin-Dependent ProteinKinase II Activity byAcute and ChronicMorphineAdministration inRat Hippocampus:DifferentialRegulation of and Isoforms

custompeptide

......purchased from AmershamInternational (Buckinghamshire,UK). Polypeptide substrate of CaMKII, autocamtide-2, was synthesizedby Genemed Synthesis, Inc. (SouthSan Francisco, CA). P81phosphocellulose paper wasobtained from Whatman(Maidstone, Eng

1999 Yan G

J. Immunol., Jan1999; 162: 852 -859

Novel Splicing ofthe Human MHC-Encoded PeptideTransporterConfers UniqueProperties

custompeptide

......corresponding cells. Bothpeptide 1 and peptide 3 weresynthesized by Quality ControlledBiochemical (Hopkington, MA), andpeptide 2 by Genemed Synthesis(San Francisco, CA), and theirsequences were confirmed by massspectrometry. The purity of al

1999 Chan JYH

Neuroscience,Volume 95,Issue 1,November 1999,Pages 155-162

Role ofcalcium/calmodulin-dependent proteinkinases inexpression of Fosprotein in the

custompeptide

PCR primers used for c-fos orGADPH in the PCR reaction

1999 Cardosa MJ

The Lancet,Volume 354,Issue 9183, 18September 1999,Pages 987-991

Isolation ofsubgenus Badenovirus during afatal outbreak ofenterovirus 71-associated hand,

custompeptide oligonucleotide primers

1999Bolander JrFF

Molecular andCellularEndocrinology,Volume 149,Issues 1-2, 25

Regulation ofprolactin receptorglycosylation andits role in receptorlocation

custompeptide

1999 Baker KA

Molecular Cell,Volume 3, Issue3, March 1999,Pages 309-319

Structural Basis forParamyxovirus-MediatedMembrane Fusion

custompeptide

1999 P PK-y

Journal ofBiochemistry,Volume 266,Issue 1: 33-39.doi:10.1046/j.1432-

Why reversing thesequence of the αdomain of humanmetallothionein-2does not change itsmetal-binding and

custompeptide

alpha domain (residues 31-61),the beta domain (residues 1-30),and the retro-alpha domain of humanliver MT-2, respectively,


EuropeanJournal ofBiochemistry,Volume 265,Issue 2: 744-

Structure of theAlzheimer β-amyloid peptide(25–35) and itsinteraction with

custompeptide betaAP(25-35) peptide

1999 Cui Y

J. Bacteriol., Oct1999; 181: 6042 - 6052

rsmC of the Soft-Rotting BacteriumErwinia carotovorasubsp. carotovoraNegatively ControlsExtracellularEnzyme andHarpinEccProduction andVirulence by miscl

harpinEcc. The anti-RsmAantiserum produced against asynthesized peptide from aminoacids 48 to 61 of RsmA () in rabbitby Genemed Biotechnologies Inc.(San Francisco, Calif.) was used asthe probe for RsmA. Construction ofrsmA-lacZ and csrA-lacZ fusion

1999 Fissore RABiol Reprod, Jan1999; 60: 49 - 57

DifferentialDistribution ofInositolTrisphosphateReceptor Isoformsin Mouse Oocytes miscl

......omission of the primaryantibody, or preincubation of theRbt02 antiserum for 1 h with 5mg/ml of the C-terminal peptide(Genemed Biotechnologies Inc.,South San Francisco, CA) beforedilution to 1:100-1:1,000 for probingthe membrane. Positive con

2000 Fang S

Endocrinology,Apr 2000; 141:1377 - 1383

Development of aTransgenic MouseThatOverexpresses aNovel Product ofthe GrowthHormone-ReleasingHormone Gene


to nitrocellulose (NitroPure, MSI,Westboro, MA), and the resultingmembrane was probed with apolyclonal primary antibody(Genemed Synthesis, Inc., SouthSan Francisco, CA) directed againstrat GHRH-RP. After washing,peptides were visualized using a hor

2000Nangia-Makker P

Am. J. Pathol.,Mar 2000; 156:899 - 909

Galectin-3 InducesEndothelial CellMorphogenesis andAngiogenesis


by extensive dialysis against PBS(pH 7.4). The pAb was prepared inrabbits against purified humanrecombinant galectin-3 (GenemedBiotechnologies, S. San Francisco,CA). The anti-galectin-3 mAb-producing hybridoma TIB-166 waspurchased from ATCC. Mouse..

2000 Keyhani NO

J. Biol. Chem.,Oct 2000; 275:33068 - 33076

Chitin Catabolismin the MarineBacterium Vibriofurnissii.IDENTIFICATIONAND MOLECULARCLONING OF ACHITOPORIN

CustomOligo/DNA

N,N-3Hdiacetylthiochitobiose (3HMe-TCB or Me-TCB ) was prepared(, ) as described. Oligonucleotideprimers were synthesized andpurchased from Genemed (SanFrancisco, CA). Purifiedphosphoenolpyruvate:glycosetransferase ( PTS ) general proteins,Enzyme

2000 Bang S-W

Appl. Envir.Microbiol., Sep2000; 66: 3939 -3944

EngineeringHydrogen SulfideProduction andCadmium Removalby Expression ofthe ThiosulfateReductase Gene(phsABC) fromSalmonella entericaSerovar

CustomOligo/DNA

......thermal cycler manufacturer(MJ Research, Inc., Waltham,Mass.). Oligonucleotide primerswere synthesized by a commercialvendor (Genemed, Inc., SanFrancisco, Calif.). The primersequences derived from thephsABC region were 5-tcagcgaattctaataacag

2000 Trumbo TA

J. Biol. Chem.,Jun 2000; 275:20627 - 20631

ExaminingThrombinHydrolysis of theFactor XIIIActivation PeptideSegment Leads toa Proposal forExplaining theCardioprotectiveEffects Observed

CustomOligo/DNA

the Cornell University BiotechnologyResource Center and GenemedSynthesis (South San Francisco,CA). The amino acidsequences...the Cornell UniversityBiotechnology Resource Center andGenemed Synthesis (South SanFrancisco, CA). The amino acidsequences

2000ChausseeMS

Infect. Immun.,Jun 2000; 68:3226 - 3232

StreptococcalErythrogenic ToxinB AbrogatesFibronectin-DependentInternalization ofStreptococcuspyogenes byCulturedMammalian Cells

CustomOligo/DNA

......Oligonucleotide primers ()emmF (5-GGCGGGAATCCACTATTCGCTTAGA-3) and emmR (5-GGCGGGAATTCAGTTCTTCAGCTTGT-3) were purchased fromGenemed Biotechnologies, Inc.(San Francisco, Calif.). Thirty cyclesof amplification were carried out witha Perkin-Elmer

2000 Jenkins JL

J. Biol. Chem.,May 2000; 275:14423 - 14431

Bivalent SequentialBinding Model of aBacillusthuringiensis Toxinto Gypsy MothAminopeptidase NReceptor

CustomOligo/DNA

......performed with a Bio-Rad Muta-Gene phagemid in vitromutagenesis kit. Mutagenic primerswere purchased from Biosynthesisor Genemed. Automated DNAsequencing with a United StatesBiochemical Corp. kit wasperformed according tomanufacturers instru

2000 Juan V

Nucleic AcidsRes., Mar 2000;28: 1221 - 1227

Evidence forevolutionarilyconservedsecondary structurein the H19 tumorsuppressor RNA

CustomOligo/DNA

identified by PCR amplification andautomatically sequenced using theSanger dideoxy method with M13forward and reverse primers(Genemed Synthesis Incorporated,San Francisco, CA). The location ofintrons in the newly determinedsequences was deduced by

2000KhlebnikovA

J. Bacteriol., Dec2000; 182: 7029 - 7034

RegulatableArabinose-InducibleGene ExpressionSystem withConsistent Controlin All Cells of aCulture

custompeptide

Mannheim (Indianapolis, Ind.) andNew England Biolabs (Beverly,Mass.). Oligonucleotide synthesisand sequencing were done byGenemed (South San Francisco,Calif.). All relevant strains andplasmids used in this study arelisted in Table . E. coli was gro

2000 Smolke CD

Appl. Envir.Microbiol., Dec2000; 66: 5399 -5405

Coordinated,DifferentialExpression of TwoGenes throughDirected mRNACleavage andStabilization bySecondaryStructures

custompeptide

used in each PCR step weresynthesized by Genemed Synthesis,Inc. DNA amplification was...variousDNA cassettes were synthesized(Genemed Synthesis, Inc.) as twocomplementary...5-CGACGGGATCTGCGATAGCTGTC-3), was synthesized (GenemedSynthesis, Inc.) to bi

2000 Goomer RS

Endocrinology,Dec 2000; 141:4613 - 4622

The TetrabasicKKKK147–150Motif DeterminesIntracrineRegulatory Effectsof PTHrP 1–173 onChondrocyte PPiMetabolism andMatrix Synthesis

custompeptide

......wild-type PTHrP peptide 140-173 and mutant PTHrP 140-173,bearing the missense mutationGQKG at the 147-150 domain(purchased from GenemedSynthesis (South San Francisco,CA), were introduced into TC28cells via permeabilization by aprotocol that

2000 Yamada H

Int. Immunol.,Dec 2000; 12:1677 - 1683.

Unusual cytotoxicactivities of thymus-independent, self-antigen-specificCD8+ T cells

custompeptide

cells of male C57BL/6 mice or thoseof female mice with various doses ofH-Y antigen peptide sequence K-C-S-R-N-R-Q-Y-L (3) (GenemedSynthesis, South San Francisco,CA). After 4 days, cells wereharvested and live cells wereanalyzed by a flow cytometer b

2000 Verrier F

J. Virol., Nov2000; 74: 10025 - 10033

A HumanImmunodeficiencyVirus Prime-BoostImmunizationRegimen inHumans InducesAntibodies ThatShow IntercladeCross-Reactivity

custompeptide

......synthesized and purified bystandard procedures as describedpreviously () and purchased fromIntracel, Inc. (Cambridge, Mass.),Genemed Biotechnologies, Inc.(South San Francisco, Calif.), orPrinceton Biomolecules Corp.(Columbus, Ohio) or provid

2000 Lin S

Shankung Lin,Wengong Wang,Gerald M. Wilson,Xiaoling Yang, GaryBrewer, Nikki J.Holbrook, andMyriam GorospeDown-Regulation ofCyclin D1Expression by

custompeptide

the peptide SPRHSEAATAQRE,encoded by exon 2 of the humanAUF1 gene, was synthesized withan N-terminal cysteine residue byGenemed Synthesis, Inc. (SouthSan Francisco, Calif.), its purityassessed by high-performanceliquid chromatography, and its ident

2000 Liu B

J. Biol. Chem.,Oct 2000; 275:33607 - 33613

Direct FunctionalInteractionsbetween Insulin-likeGrowth Factor-binding Protein-3and Retinoid XReceptor-RegulateTranscriptionalSignaling and

custompeptide

extracts were purchased from SantaCruz Biotechnology, Inc. (SantaCruz, CA). IGFBP-3 blockingpeptides were purchased fromGenemed Synthesis (South SanFrancisco, CA). Retinoic acid,dimethyl sulfoxide, and Igepal CA-630 were purchased from Sigma.Tris..

2000 Balija VS

J. Biol. Chem.,Oct 2000; 275:31668 - 31673

Identification ofTwoTransmembraneRegions and aCytosolic Domainof RatMitochondrialGlycerophosphateAcyltransferase

custompeptide

regions of rat mitochondrial GATwere purchased from GenemedSynthesis, Inc. Briefly, the companywas supplied with...Enzyme-linkedimmunosorbent assay titersperformed by Genemed for each thethree anti-serum types against theirrespective

2000 Nguyen VTAm. J. Pathol;157: 1377 - 1391

Novel Human 9AcetylcholineReceptorRegulatingKeratinocyteAdhesion isTargeted byPemphigusVulgarisAutoimmunity

custompeptide

......terminus of a9 AChR 33,34(cwhdayltwdrdqydrld andcnkaddessepvntn; residues 65-81and 99-112, respectively)synthesized at Genemed Synthesis,Inc. (San Francisco, CA). Toimmunoaffinity purify rabbit anti-AChR antibodies, the peptides werecovalent

2000 Pilon M

Mol. Biol. Cell,Oct 2000; 11:3277 - 3288

The DiabetesAutoantigen ICA69and ItsCaenorhabditiselegansHomologue, ric-19,Are ConservedRegulators ofNeuroendocrineSecretion

custompeptide

generated by immunizing a rabbitagainst a peptide corresponding tothe 20 C-terminal amino acids of thepredicted RIC-19 protein (GenemedSynthesis, San Francisco, CA).Antibody 6097 was affinity purifiedwith the peptide used forimmunization and used a

2000 Yu W-H

J. Biol. Chem.,Sep 2000; 275:31226 - 31232

TIMP-3 Binds toSulfatedGlycosaminoglycans of theExtracellular Matrix

custompeptide

TIMP-3 and RHAMM401-411 (aheparin-binding peptide from theReceptor for Hyaluronic Acid-Mediated Mobility) were synthesized(Genemed). RESULTS SulfatedGlycosaminoglycans Extract TIMP-3from Postpartum Rat Uterus TissueVarious sulfated compounds......

2000 Tan NS

FASEB J, Sep2000; 14: 1801 -1813

Definition ofendotoxin bindingsites in horseshoecrab Factor Crecombinant sushiproteins andneutralization ofendotoxin by sushipeptides

custompeptide

......making buffers was from Baxter(Morton Grove, Ill.). Peptides FactorC-derived peptides weresynthesized and purified byGenemed Synthesis, Inc. (SanFrancisco, Calif.). The first peptide,N-GFKLKGMARISCLPNGQWSNFPPKCIRECAMVSS-C, corresponding tore

2000 Liu C

J. Biol. Chem.,Aug 2000; 275:24490 - 24499

MammalianPeptidoglycanRecognition ProteinBindsPeptidoglycan withHigh Affinity, IsExpressed inNeutrophils, andInhibits BacterialGrowth

custompeptide

manufacturer and then usingautomatic sequencing performed atGenemed Synthesis (South SanFrancisco, CA). Generationof...peptides were synthesized andpurified (95 pure) by HPLC byGenemed Synthesis (South SanFrancisco, CA) and then coupledto......

2000 Gao YJ. Clin. Invest;106: 439 - 448

Inhibition ofubiquitin-proteasomepathway–mediatedI B degradation bya naturallyoccurringantibacterial peptide

custompeptide

described previously (32). SyntheticPR39 peptide was generated on thebasis of porcine sequence (26) andpurified by HPLC (GenemedSynthesis Inc., South SanFrancisco, California, USA).Lactacystin and MG132 wereobtained from Calbiochem-Novabiochem Corp

2000 Liu RY

J. Biol. Chem.,Jul 2000; 275:21086 - 21093

Activation of p38Mitogen-activatedProtein Kinase IsRequired for TumorNecrosis Factor- -supportedProliferation ofLeukemia andLymphoma CellLines

custompeptide

......Both SN50 and SN50mt weresynthesized commercially(Genemed Synthesis, South SanFrancisco, CA). The peptideswere...29). Both SN50 and SN50mtwere synthesized commercially(Genemed Synthesis, South SanFrancisco, CA). The peptides were

2000 Hastings RH

Am J PhysiolLung Cell MolPhysiol, Jul2000; 279: 194 -200

Parathyroidhormone-relatedprotein reducesalveolar epithelialcell proliferationduring lung injury inrats

custompeptide

......Antibody (Berkeley, CA). Theantigenic peptide for the PTHrPreceptor antibody, NH2-ESKENKDVPTGSRRRGR-COOH(), was purchased from GenemedBiotechnologies (South SanFrancisco, CA). Biotinylated goatanti-mouse and anti-rabbit IgGantibodies were pu

2000 Jeng JH

Carcinogenesis,Jul 2000; 21:1365 - 1370

Areca nut extractup-regulatesprostaglandinproduction,cyclooxygenase-2mRNA and proteinexpression ofhuman oralkeratinocytes

custompeptide

......was prepared and weighed asdescribed previously (4,5). SpecificPCR primer sets for COX-2 andbeta-actin were synthesized byGenemed Biotechnologies, Inc.(San Francisco, CA). Mouse anti-human COX-2 monoclonal antibodywas purchased from Transduct

2000Kumaraguru U

J. Virol., Jun2000; 74: 5709 -5711

Application of theIntracellularGamma InterferonAssay ToRecalculate thePotency of CD8+ T-Cell Responses toHerpes SimplexVirus

custompeptide

......respectively) for 10 to 12 h. Aportion of C57BL/6 splenocytes wasalso stimulated with SSIEFARL(HSVgB498-505synthesized atGenemed Synthesis, Inc., SanFrancisco, Calif.) peptide (1 mg/ml)for 6 h, in a 96-well flat-bottomedplate at a concentrat

2000 Arregui C

J. Cell Biol., Jun2000; 149: 1263 - 1274

The NonreceptorTyrosine KinaseFer Mediates Cross-talk between N-Cadherin and ß1-Integrins

custompeptide

Fer were synthesized as fusionswith the antennapediahomeodomain cell permeationsequence ( ) and purified to >90%by HPLC (GenemedBiotechnologies, Inc. see 1 ): controlantennapedia peptide (COP),RQIKIWFQNRRMKWKK cateninbinding peptide (CBP), RQIKIWF

2000 Li H

J. Cell Biol., Jun2000; 149: 1275 - 1288.

CoordinateRegulation ofCadherin andIntegrin Function bythe ChondroitinSulfateProteoglycanNeurocan

custompeptide

......antennapedia homeodomain ( )and sequences from the N-cadherincytoplasmic domain () weresynthesized and purified to >90% byHPLC (Genemed Biotechnologies,Inc.). All peptides were dissolved insterile deionized water, stored insmall aliquots at

2000 Sun F

J. Biol. Chem.,May 2000; 275:14360 - 14366

Protein Kinase AAssociates withCystic FibrosisTransmembraneConductanceRegulator via anInteraction withEzrin

custompeptide

AKAP in secretory epithelial cells.EXPERIMENTAL PROCEDURESMaterials Ht31 and Ht31P peptides(, ) were obtained from GenemedSynthesis (San Francisco, CA).Protein A/G-agarose beads andmolecular weight markers wereobtained from Life Technologies

2000Wooton-Kee CR

Endocrinology,Apr 2000; 141:1345 - 1355

SteroidogenicFactor-1 InfluencesProtein-DeoxyribonucleicAcid Interactionswithin the CyclicAdenosine 3',5'-Monophosphate-ResponsiveRegions of the

custompeptide

......from NEN Life ScienceProducts (Wilmington, DE). Customoligonucleotides were purchasedfrom Genosys (The Woodlands, TX)and Genemed Synthesis, Inc. (SanFrancisco, CA). Glutathione-S-transferase (GST)-SF-1 plasmidwas donated by Dr. Keith Parker,

2000 Schense JC

J. Biol. Chem.,Mar 2000; 275:6813 - 6818

Three-dimensionalMigration ofNeurites IsMediated byAdhesion SiteDensity and Affinity

custompeptide

......pH 7.0, as the running buffer.The cyclic peptide, NH2-LNQEQVSPDCRGDNRC (cyclicring shown in brackets), waspurchased from Genemed (SouthSan Francisco, CA) at greater than85 purity. Fibrinogen solutions wereprepared by dissolving fibrinogen (Fl

2000 Wilson HL

J. Bacteriol., Mar2000; 182: 1680 - 1692.

Biochemical andPhysical Propertiesof theMethanococcusjannaschii 20SProteasome andPAN, a Homolog ofthe ATPase (Rpt)Subunits of theEucaryal 26SProteasome

custompeptide

DNA-modifying enzymes were fromNew England BioLabs (Beverly,Mass.) or Promega (Madison, Wis.).Oligonucleotides were fromGenemed Synthesis (SanFrancisco, Calif.). Polyvinylidenedifluoride membranes were fromMicroSeparations (Westborough,Mass.). The

2000 Yu W-H

J. Biol. Chem.,Feb 2000; 275:4183 - 4191

Heparan SulfateProteoglycans asExtracellularDocking Moleculesfor Matrilysin(MatrixMetalloproteinase 7)

custompeptide

......synthesized and high pressureliquid chromatography-purified(Genemed). They were disulfide-linked to maleimide-activatedkeyhole...competitors for heparin.Type I collagen and RHAMM401-411 (Genemed) are positivecontrols; bovine serum albumin is a

2000Kokai-KunJF

J. Biol. Chem.,Feb 2000; 275:3713 - 3721

Elastase inIntestinal MucusEnhances theCytotoxicity ofShiga Toxin Type2d

custompeptide

......specific for the A2 fragment ofStx2d was generated at GenemedBiotechnologies Inc. (SanFrancisco, CA) by injectingrabbits...specific for the A 2fragment of Stx2d was generated atGenemed Biotechnologies Inc. (SanFrancisco, CA) by injecting rab

2000 Zhu W

Drug Metab.Dispos., Feb2000; 28: 186 -191

DexamethasoneDifferentiallyRegulatesExpression ofCarboxylesteraseGenes in Humansand Rats

custompeptide

......H2N-CQELEEPEERHTEL-COOH; and CYP3A4, H2N-CVKRMKESRLEDTQKHRVDFLQ-COOH. Peptides were synthesizedand conjugated with keyhole limpethemocyanin (Genemed SynthesisInc., South San Francisco, CA). Thefirst immunization was conducted byinjecting each

2000 Harb OS

Infect. Immun.,Jan 2000; 68:368 - 376

Characterization ofa Macrophage-Specific InfectivityLocus (milA) ofLegionellapneumophila

custompeptide

Oligonucleotide synthesis for PCRwas done by Integrated DNATechnologies Inc. (Coralville, Calif.).Sequencing was carried out byGenemed Synthesis Inc. (South SanFrancisco, Calif.). Sequencecomparisons and alignments wereperformed with the BlastX and

2000 Myers JM

J. Bacteriol., Jan2000; 182: 67 -75.

Role of theTetrahemeCytochrome CymAin AnaerobicElectron Transportin Cells ofShewanellaputrefaciens MR-1with Normal Levelsof Menaquinone

custompeptide

......England BioLabs (Beverly,Mass.). Custom oligonucleotideprimers were synthesized byOperon Technologies (Alameda,Calif.) or by GenemedBiotechnologies (South SanFrancisco, Calif.). Vitamin K2(menaquinone-4, MK-4) andcoenzyme Q6 (ubiquinone-6)

2000 Erdem A

AnalyticaChimica Acta,Volume 422,Issue 2, 12November 2000,Pages 139-149

Novel hybridizationindicator methyleneblue for theelectrochemicaldetection of shortDNA sequences

custompeptide

29-mer and 21-mer syntheticoligonucleotides

2000 Brubaker K

Cell, Volume103, Issue 4, 10November 2000,Pages 655-665

Solution Structureof the InteractingDomains of theMad–Sin3Complex:Implications for

custompeptide

hexadecapeptide corresponding toresidue 6-21 of Mad1 (SID)

2000 Ding J

FEMSImmunology andMedicalMicrobiology,Volume 29,Issue 2, October

Candidate multi-epitope vaccines inaluminium adjuvantinduce high levelsof antibodies withpredefined multi-

custompeptide

Seven peptides containing epitopesonHIV-1III envelope proteins

2000 Doebele RC

Immunity,Volume 13,Issue 4, 1October 2000,Pages 517-527

Determination ofthe HLA-DMInteraction Site onHLA-DR Molecules

custompeptide

Human CLIP with a C-terminallysine(LPKPPKPVSKKMRMATPLLMQALPK

2000 Wang P

Journal ofMolecularBiology, Volume302, Issue 4, 29September 2000,

II. Structure andspecificity of theinteraction betweenthe FHA2 domainof rad53 and

custompeptide Rad9 pTyr peptide (EDI(pY)(YLD)

2000 Balaban N

Peptides,Volume 21,Issue 9,September 2000,

Prevention ofdiseases caused byStaphylococcusaureus using the

custompeptide RIPb(YSPWTNF)

2000 Wang P

FEBS Letters,Volume 475,Issue 2, 16 June2000, Pages 107-110

Identification ofalternative splicingvariants of the βsubunit of humanCa2+/calmodulin-dependent protein

custompeptide autocamtide-2

2000 Messmer TB

MolecularImmunology,Volume 37,Issue 7, May

C1q-bindingpeptides sharesequence similaritywith C4 and induce

custompeptide

2000 Menoret A

Journal ofImmunologicalMethods,Volume 237,

Purification ofmultiple heat shockproteins from asingle tumor sample

custompeptide

125 I-labeled VSV19 peptide(SLSDLRGYVYQGLKSGNVS)

2000 Liao M

Peptides,Volume 21,Issue 4, April2000, Pages 463-468

Induction of highlevel of specificantibody responseto the neutralizingepitope ELDKWA

custompeptide

ELDKWA-tetramer peptide E/2F4 ofgp41; carrier peptide K/G ((KGGG7-K))

2000DuchosalMA

ExperimentalHematology,Volume 28,Issue 2,February 2000,Pages 177-192

Human adult tonsilxenotransplantationinto SCID mice forstudying humanimmune responsesand B celllymphomagenesis

custompeptide

33P-labeled EBV oligonucleotideprobe (59-TAC CTG GGA TCG AAT GACAGA GAAGCT GCT TGT CTC CGC A-39

2000 Prasad R

Journal ofPediatricSurgery, Volume35, Issue 2,February 2000,

Glucagonlikepeptide-2 analogueenhances intestinalmucosal mass afterischemia and

custompeptide

2000 Ding J

Immunology &MedicalMicrobiology,Volume 29,Issue 2: 123-127. doi:10.1111/j.1574-695X.2000.tb01514.x

Candidate multi-epitope vaccines inaluminium adjuvantinduce high levelsof antibodies withpredefined multi-epitope specificityagainst HIV-1FEMS

custompeptide

MP:CGGPGRAFYGELDKWAGRILAVERYLKDK(317-323, 669-674, 586-596).(V3)4: C-(GPGRAFY)4 (317-323).V3 loop: C-TRPNNNTRKSIRIQRGPGRAFYTIGKI(301-328).(P1)2 : C-(RILAVERYLKD-G)2 (586-596).P1: LQARILAVERYLKDQQL (583-599).(2F5)4: C-(ELDKWAG)4 (669-674).P2: C-TS

2000 Morgan H

FASEB J, Jun2000; 14: 1109 -1116

The transactivation-competent carboxyl-terminal domain ofAF-9 is expressedwithin a sexuallydimorphic transcriptin rat pituitary miscl

......residues 282-295 of the largestrAF-9 ORF) as immunogen(Genemed Synthesis Inc., SanFrancisco, Calif.). The peptidesequence...affinity purification andenzyme-linked immunoassayanalysis (Genemed), the antiserumwas used to probe Western blots of

2000 Romanin C

FEBS Letters,Volume 487,Issue 2, 29December 2000,

Ca2+ sensors of L-type Ca2+ channel miscl

2000 Lu

ScandinavianJournal ofImmunology,Volume 51,Issue 5: 497-501. doi:10.1046/j.1365-

MultiepitopeVaccinesIntensivelyIncreased Levels ofAntibodiesRecognizing ThreeNeutralizing miscl

2000 Ozkan Se

InternationalJournal ofDermatology,Volume 39,Issue 4: 278-

Evidence forBorrelia burgdorferiin morphea andlichen sclerosus miscl

2001 Querido E

Genes & Dev.,Dec 2001; 15:3104 - 3117

Degradation of p53by adenovirusE4orf6 and E1B55Kproteins occurs viaa novel mechanisminvolving a Cullin-containing complex


......from Maria Burnatowska-Hledin(Hope College, Holland, MI). Arabbit polyclonal antibody againsthuman Cul5 was made for us byGenemed Synthesis Inc. using asynthetic peptide(EHKIRRDESDINTFIYMA)corresponding to the C terminus ofhuman Cul5. Anti-

2001 Mack AM

PLANT CELL,Oct 2001; 13:2319 - 2331

The ArabidopsisTAG1 TransposaseHas an N-TerminalZinc Finger DNABinding DomainThat RecognizesDistinctSubterminal Motifs


cysteine residue added to the Cterminus for eventual conjugation.Peptide synthesis and antibodyproduction were performed byGenemed Synthesis (SanFrancisco, CA). Affinity purificationof TAG1-specific antibodies wasperformed using the SulfoLink Kit (

2001 Kang MG

J. Biol. Chem.,Aug 2001; 276:32917 - 32924

Biochemical andBiophysicalEvidence for 2Subunit Associationwith NeuronalVoltage-activatedCa2+ Channels


......respectively, have beendescribed previously (, ). The 3subunit-specific polyclonal antibody,Rabbit 302, was generated byGenemed Synthesis (South SanFrancisco, CA) against an amino-terminal cysteine 12-mer peptide(Research Genetics, Huntsville

2001 Wong GW

J. Biol. Chem.,Dec 2001; 276:49169 - 49182

Human Tryptase(PRSS22), a NewMember of theChromosome16p13.3 Family ofHuman Serine

CustomOligo/DNA

Tryptase cDNAs Tryptase -specificAntibody ,V5 peptide ,FLAG peptide,Goat anti-mouse immunoglobulin G(Bio-Rad),

2001 Maruyama Y

Invest.Ophthalmol. Vis.Sci., Aug 2001;42: 1980 - 1985

Involvement of Sp1Elements in thePromoter Activity ofGenes Affected inKeratoconus

CustomOligo/DNA

TTGGCGTTGCCGGAGCGGTT;and for a2-M, US,TCTGTAGCAAACATAGGATC, andDS, TCTGGTCCCAAACACTTCCC.All primers were synthesized byGenemed Biotechnologies, Inc.(South San Francisco, CA). ThePCR products were analyzed on a1.0% agarose gel and were clonedinto

2001 Heredia J

J. Biol. Chem.,Mar 2001; 276:8793 - 8797

Phosphorylationand Cu+Coordination-dependent DNABinding of theTranscriptionFactor Mac1p in theRegulation ofCopper Transport

CustomOligo/DNA

optimal codons and is tagged with asingle copy of HA epitope at thecarboxyl terminus. The DNA wassynthesized in vitro (GeneMed). Asingle copy plasmid pRSMac1(3HA)was constructed essentially thesame as pRSMac1( HA ) asdescribed previously (). To int

2001 Knowle D

Peptides,Volume 22,Issue 12,December 2001,

Role of Asp297 ofthe AT2 receptor inhigh-affinity bindingto different peptide

CustomOligo/DNA

ligand Sar-Asp-Val-Tyr-Ile-His-Pro-Ile

2001 Cui S-S

J. Neurosci., Dec2001; 21: 9867 -9876

Prevention ofCannabinoidWithdrawalSyndrome byLithium:Involvement ofOxytocinergicNeuronal Activation

custompeptide

......s.c., dissolved in physiologicalsaline; Sigma), oxytocin fragment 4-9 (2 Mg/kg, s.c., dissolved inphysiological saline; GenemedSynthesis Inc., San Francisco, CA)or saline injection 15 min beforeAM281 precipitation (Table , groups19-21); (2) u

2001 Secher T

J. Biol. Chem.,Dec 2001; 276:47052 - 47060

Molecular Cloningof a FunctionalAllatostatinGut/Brain Receptorand an AllatostatinPreprohormonefrom the SilkwormBombyx mori

custompeptide

......Probes) was added to a finalconcentration of 5 Mm 3 h prior tothe assay (). Peptides, which were95 pure and synthesized byGenemed Synthesis Inc. (SanFrancisco, CA), were diluted inphosphate-buffered saline, warmedup to 37C, and 100 Ml was ad

2001KhlebnikovA

Microbiology,Dec 2001; 147:3241 - 3247

Homogeneousexpression of thePBAD promoter inEscherichia coli byconstitutiveexpression of thelow-affinity high-capacity AraEtransporter

custompeptide

System (Roche MolecularBiochemicals) under the conditionsrecommended by the manufacturer.Oligonucleotides were synthesizedby Genemed Synthesis. Therestriction digests and ligationreactions were performed asrecommended by the restrictionenzyme manu

2001 Xiao G-Q

Am J PhysiolCell Physiol, Nov2001; 281:C1477 - C1486

Evidence forfunctional role ofPKC isozyme in theregulation ofcardiac Na+channels

custompeptide

......aC2-4 (SLNPQWNET; aPKCantagonist), bC2-4 (SLNPEWNET;bPKC antagonist), and V1-2(EAVGLQPT; PKC antagonist) weresynthesized at Genemed Synthesis(South San Francisco, CA). Allpeptides used were 90 pure. Allchemicals were purchased fromSigma or

2001 Zhang C

J. Biol. Chem.,Oct 2001; 276:40614 - 40620

Ternary Complexesand CooperativeInterplay betweenNCoA-62/Ski-interacting Proteinand SteroidReceptorCoactivators inVitamin D Receptor-mediatedTranscription

custompeptide

mammalian expression vector(Stratagene). NR Box II(KHKILHRLLQDSS) and NR Box III(ENALLRYLLDKDD) peptides werepurchased from GenemedSynthesis, Inc. (South SanFrancisco, CA). NCoA-62 DeletionConstructs Deletion mutants ofNCoA-62 were generated by po

2001 Li Y

J. Biol. Chem.,Oct 2001; 276:40982 - 40990

MARCKS Protein Isa Key MoleculeRegulating MucinSecretion byHuman AirwayEpithelial Cells inVitro

custompeptide

Peptides Both the myristoylated N-terminal sequence (MANS) and therandom N-terminal sequence (RNS)peptides were synthesized atGenemed Synthesis, Inc. (SanFrancisco, CA), then purified by highpressure liquid chromatography (95pure), and confirmed by

2001 Chan SF

J. Neurosci., Oct2001; 21: 7985 -7992

An NMDA ReceptorSignaling Complexwith ProteinPhosphatase 2A

custompeptide

......Technologies Inc.), was addedand incubated at 30C for 30 min.Peptide synthesis. Synthetic peptide(SP1) was purified by HPLC(Genemed Synthesis, SanFrancisco, CA). The amino acidsequence of the synthetic peptidewas:GEHIVHRLLLPRIKNKSKLQYWLHTSQ

2001 Guo R

Am J PhysiolEndocrinolMetab, Oct 2001;281: E837 - E847

Analysis ofrecombinant Phex:an endopeptidasein search of asubstrate

custompeptide

......mutant peptide (172-PIPRQHTQSAEDDSE-186) thatsubstitutes glutamine for arginine atpositions 176 and 179 weresynthesized by Genemed Synthesis(San Francisco, CA).Leuenkephalin, consisting of thesequence YGGFL, was obtainedfrom Bachem Bioscienc

2001ArmstrongCE

J. Physiol., Oct2001; 536: 49 -65

Rapidly inactivatingand non-inactivating calcium-activatedpotassium currentsin frog saccular haircells

custompeptide

which constitutes the aminoterminus of the BK channel 2subunit (Wallner et al. 1999; Xia etal. 1999), was synthesized byGenemed Synthesis, Inc. (SouthSan Francisco, CA, USA). Inexperiments in which we appliedtrypsin (bovine pancreatic;Worthington

2001 MarinO MMol. Endocrinol;15: 1829 - 1837

Binding of the LowDensity LipoproteinReceptor-Associated Protein(RAP) toThyroglobulin (Tg):Putative Role ofRAP in the TgSecretory Pathway

custompeptide

corresponding to a sequence(RELPSRRLKRPLPVK, Arg2489-Lys2503) in the carboxyl-terminalportion of rat Tg (20), wassynthesized by GenemedBiotechnologies (South SanFrancisco, CA). RAP was used inthe form of a GST fusion protein.DH5a bacteria harboring

2001 Eo SK

J. Immunol., Oct2001; 167: 3592 - 3599

Plasmid DNAEncoding CCR7LigandsCompensate forDysfunctional CD8+T Cell Responsesby Effects onDendritic Cells

custompeptide

......specific for MHC class I (H-2b)-restricted CD8 T lymphocytes (25,26) was chemically synthesized,purified, and quantitated byGenemed Synthesis (South SanFrancisco, CA). Plasmid DNApreparation Plasmid DNA encodingCCL21 or CCL19 was kindly provi

2001PiechockiMP

J. Immunol., Sep2001; 167: 3367 - 3374

ComplementaryAntitumor ImmunityInduced by PlasmidDNA EncodingSecreted andCytoplasmicHuman ErbB-2

custompeptide

......calf serum at 37C for 2 h. Insome experiments, the target cellswere simultaneously incubated withpeptide E63 (TYLPTNASL;Genemed Synthesis, South SanFrancisco, CA) at 200 Mg/ml. Theunincorporated 51Cr was removedby three washes with HBSS 2% c

2001 Phenix BNBlood, Aug 2001;98: 1078 - 1085

Antiapoptoticmechanism of HIVprotease inhibitors:preventingmitochondrialtransmembranepotential loss

custompeptide

anti-Fas antibody (CH11; 0.5Mg/mL; Beckman Coulter,Mississauga, ON, Canada), orrecombinant synthetic Vpr peptide.For Vpr (Genemed Systems, SanFrancisco, CA) stimulation, cellswere incubated in isotonic bufferwith 2.5 MM synthetic Vpr peptide(resid

2001BergmannCC

J. Immunol., Aug2001; 167: 1575 - 1583

Impaired T CellImmunity in B Cell-Deficient MiceFollowing ViralCentral NervousSystem Infection

custompeptide

......Microchemistry Laboratory andpurity assessed by HPLC and massspectrometry. The I-Ab-restrictedM133 peptide (39) was purchasedfrom Genemed Synthesis (SouthSan Francisco, CA). Peptides weresolubilized at 1 mM in DMSO anddiluted in sterile PBS.

2001 Guo F-Q

PLANT CELL,Aug 2001; 13:1761 - 1777

The ArabidopsisDual-Affinity NitrateTransporter GeneAtNRT1.1 (CHL1)Is Activated andFunctions inNascent OrganDevelopmentduring Vegetativeand Reproductive

custompeptide

......were made against the N-terminal peptide of CHL1(MSLPETKSDDILLDA, with a Cysresidue added at the C terminus forcoupling) by Genemed Synthesis(South San Francisco, CA). Antiserawere purified by antigen affinitychromatography with CHL1 peptide-

2001 Lenart J

Antimicrob.AgentsChemother., Aug2001; 45: 2198 -2203

Growth andDevelopment ofTetracycline-ResistantChlamydia suis

custompeptide

......Rabbit antiserum against apeptide (CGAGKVEDKGSAGELC)in the strain R19 major outermembrane protein (MOMP) wasproduced by Genemed Synthesis,Inc. (San Francisco, Calif.). Thepeptide was linked to keyhole limpethemocyanin and administered incom

2001 Erlenbach I

J. Biol. Chem.,Jul 2001; 276:29382 - 29392

Single Amino AcidSubstitutions andDeletions That Alterthe G ProteinCoupling Propertiesof the V2VasopressinReceptor Identifiedin Yeast byReceptor Random

custompeptide

......region coding for the i2 loop(see Fig. ), the followingoligonucleotide coding for V2receptor residues 134-164 was used(Genemed Synthesis, Inc., SanFrancisco, CA; underlines denotebases doped with 10 non-wild-typenucleotides): 5-ACG CTG GAC C

2001 Dumont RA

J. Neurosci., Jul2001; 21: 5066 -5078

Plasma MembraneCa2+-ATPaseIsoform 2a Is thePMCA of HairBundles

custompeptide

......Synthetic PMCA peptides,designed with an added N- or C-terminal cysteine residue, were usedfor the production of antisera(GeneMed Synthesis, South SanFrancisco, CA). To purifyantipeptide antibodies, we coupledpeptides to SulfoLink resin (Pier

2001 Buczynski G

J. Biol. Chem.,Jul 2001; 276:27231 - 27236

Characterization ofa Lidless Form ofthe MolecularChaperone DnaK.DELETION OFTHE LIDINCREASESPEPTIDE ON- ANDOFF-RATECONSTANTS

custompeptide

which were conducted at theUniversity of Nebraska (ProteinStructure Core Facility, Omaha).Peptides were synthesized byGenemed Synthesis Inc. (South SanFrancisco), purified to 95 by HPLC ,and peptide mass was verified byelectrospray mass spectroscop

2001 Denkberg G

J. Immunol., Jul2001; 167: 270 -276

Critical Role forCD8 in Binding ofMHC Tetramers toTCR: CD8Antibodies BlockSpecific Binding ofHuman Tumor-Specific MHC-Peptide Tetramersto TCR

custompeptide

......the peptide TAX (LLFGYPVYV),derived from human T cell leukemiavirus (HTLV)-1, were synthesized bystandard techniques by GenemedSynthesis (South San Francisco,CA) and were 95% pure. Productionof scMHC-peptide tetramers wasperformed as describ

2001 Cunnick JM

J. Biol. Chem.,Jun 2001; 276:24380 - 24387

Phosphotyrosines627 and 659 ofGab1 Constitute aBisphosphorylTyrosine-basedActivation Motif(BTAM) ConferringBinding andActivation of SHP2

custompeptide

......purchased from Calbiochem.Gab1-derived peptides PY589,PY627, PY659, PY627PY659, andY627Y659 were synthesized andpurified by Genemed Synthesis, Inc.The amino acid sequences of thesepeptides are (pY denotesphosphotyrosine residue): PY589:DSEE

2001 Young LH

Am J PhysiolHeart CircPhysiol, Jun2001; 280: 2489 - 2495

Caveolin-1 peptideexertscardioprotectiveeffects inmyocardialischemia-reperfusion vianitric oxidemechanism

custompeptide

9 NaCl intravenously 1 h before theexperiments. Caveolin-1 peptide(molecular weight = 2,518; aminoacid residues 82-101, GenemedSynthesis) was prepared in 0.9NaCl, pipetted into 0.5-ml aliquots,and stored at 20C. Aliquots werethawed once just before

2001 Yao C

Infect. Immun.,Jun 2001; 69:4065 - 4071

Trichinella spiralis-Infected MuscleCells: AbundantRNA Polymerase IIin Nuclear SpeckleDomainsColocalizes withNuclear Antigens

custompeptide

......A peptide containing threecontiguous PTSPSYS motifs wassynthesized, purified by high-pressure liquid chromatography(Genemed Synthesis, Inc., SanFrancisco, Calif.; 96.7 purity), andused in antibody inhibitionexperiments. Two control peptides w

2001 Glavas NA

PNAS, May2001; 98: 6319 -6324

T cell activation up-regulates cyclicnucleotidephosphodiesterases 8A1 and 7A3

custompeptide

specific for the N terminus (PIL9:MGCAPSIHTSENRTF) of mousePDE8A1. The PDE7A3 peptidepolyclonal antibody was obtainedfrom Genemed Biotechnologies(South San Francisco, CA) and isspecific for the C terminus (6976:QIGNYTYLDIAG) of this enzyme.CD4 T..

2001 Gerson JH

J. Biol. Chem.,May 2001; 276:18442 - 18449

Tropomyosin-TroponinRegulation of ActinDoes Not InvolveSubdomain 2Motions

custompeptide

in D51C the PleI site is lost while inC374S the HindIII is added). Actingenes from screened plasmidclones were sequenced (GeneMed,San Francisco, CA) to confirm theabsence of random errors. Theconstruction of the Q41C andQ41C/C374S mutants was repor

2001 Baocheng H

J. Biol. Chem.,May 2001; 276:17693 - 17698

TheRadioresistance toKilling of A1-5 CellsDerives fromActivation of theChk1 Pathway

custompeptide

......region of Chk1 or Chk2 mRNA.The oligonucleotides used in thisstudy are phosphorothioateoligodeoxynucleotides synthesizedby Genemed Synthesis, Inc. Theoligonucleotides were delivered tocells by OligofectAMINETM (LifeTechnologies, Inc.) accord

2001 Cheng Q

J. Neurosci., May2001; 21: 3419 -3428

Suppression ofNeuronalHyperexcitabilityand AssociatedDelayed NeuronalDeath byAdenoviralExpression ofGABAC Receptors

custompeptide

peptide conjugated with keyholelimpet hemocyanin(QRQRREVHEDAHK) ( Hackam etal., 1997 ) was prepared and affinitypurified by Genemed Synthesis(South San Francisco, CA). Doubleimmunohistochemical staining forGFP and P1 subunit proteins wasaccomplish

2001 Binder RJ

J. Biol. Chem.,May 2001; 276:17163 - 17171

Heat Shock Protein-chaperonedPeptides but NotFree PeptidesIntroduced into theCytosol ArePresentedEfficiently by MajorHistocompatibilityComplex IMolecules

custompeptide

NH2-RHRVSAINNYAQKLCTFSFL-COOH; T-Ag 20-mer (C terminusextended), NH2-AINNYAQKLCTFSFLICKGV-COOH. Peptides were synthesizedby Genemed to 95 purity asdetermined by high pressure liquidchromatography. The unextendedMHC I binding 9-mer peptide isidentica

2001 Dery O

Am J PhysiolCell Physiol, May2001; 280:C1097 - C1106.

Protein kinase C-mediateddesensitization ofthe neurokinin 1receptorAm J Physiol CellPhysiol, May 2001;280: C1097 -C1106.

custompeptide

......was from Promega (Madison,WI). The expression vector pcDNA3was from Invitrogen (Carlsbad, CA).Oligonucleotides were fromGenemed Biotechnologies (SanFrancisco, CA). Lipofectin, DMEM,and PBS were from LifeTechnologies (Gaithersburg, MD).G418

2001 Binder RJJ. Immunol; 166:4968 - 4972

Adjuvanticity of 2-Macroglobulin, anIndependent Ligandfor the Heat ShockProtein ReceptorCD91

custompeptide

......C57BL/6 mice (The JacksonLaboratory, Bar Harbor, ME) byflushing with cold PBS. PeptidesAH1-20 and OVA20 weresynthesized at Genemed Synthesis(San Francisco, CA). AH1-20 refersto a 20-mer extended variant (NH2-RVTYHSPSYVYHQFERRAK-COOH) of the L

2001 Lai A

Mol. Cell. Biol.,Apr 2001; 21:2918 - 2932

RBP1 Recruits themSIN3-HistoneDeacetylaseComplex to thePocket ofRetinoblastomaTumor SuppressorFamily ProteinsFound in LimitedDiscrete Regions ofthe Nucleus at

custompeptide

......polyclonal antiserum wasproduced commercially by injectingan amino-terminal RBP1 peptide(CLKQDNTTQLVQDDQVKGPLRV)into rabbits (Genemed SynthesisInc.). Monoclonal antibody NM11against p300 was kindly provided byBetty Moran (). Antibodies again

2001DeshpandeSP

J. Virol., Apr2001; 75: 3077 -3088

Herpes SimplexVirus-InducedKeratitis: Evaluationof the Role ofMolecular Mimicryin LesionPathogenesis

custompeptide

......University of Pittsburgh,Pittsburgh, Pa.). UL6 (299-314),IgG2a (292-308), and hemagglutinin(HA) peptides were synthesized byGenemed Synthesis, Inc., SouthSan Francisco, Calif. Corneal HSVinfections and clinical observations.Corneal infection

2001 Grimwood J

Infect. Immun.,Apr 2001; 69:2383 - 2389

Expression ofChlamydiapneumoniaePolymorphicMembrane ProteinFamily Genes

custompeptide

......cysteine added to the nativesequence to facilitate conjugation.Peptides were synthesized usingsolid-phase techniques byGenemed Synthesis Inc. (South SanFrancisco, Calif.) and conjugated tokeyhole limpet hemocyanin (KLH)using Sulfo-SMCC cross

2001Mollaaghababa R

PNAS, Mar2001; 98: 3958 -3963

Mutations inDrosophila heatshock cognate 4are enhancers ofPolycomb

custompeptide

......resin for 4.5 h at 4C. Boundproteins were washed with 40volumes of IP buffer and eluted with100 Ml of 0.5 mgml HA dipeptide(GeneMed Synthesis) in IP buffer(30 min, room temperature). BRMwas detected by Western blottingwith affinity-purified

2001 Zhang L

J. Biol. Chem.,Mar 2001; 276:10476 - 10484

StructuralProperties andMechanisms ThatGovern Associationof C KinaseAdapter 1 withProtein Kinase C3and the CellPeriphery

custompeptide

......presence of the indicatedconcentrations of a 15-mer peptide(Genemed Inc.) whose sequence(SGGGIDNGAFHEHEI, designatedCBSP...also performed with arandomly scrambled 15-mer peptide(Genemed Inc.) that has the sameamino acids arranged in a distin

2001 Dai B

J. Biol. Chem.,Mar 2001; 276:6937 - 6944

Identification of aNovel Cis ElementRequired for CellDensity-dependentDown-regulation ofInsulin-like GrowthFactor-2 P3Promoter Activity inCaCo2 Cells

custompeptide

Fig. ) that contained arepresentative P3 core promoter(712/140). Two pairs of 100-bpoligonucleotides were synthesized(Genemed Syn Inc.) for ligation tothe homologous core P3 promoter.The WT sense and antisenseoligonucleotide sequencesrepresented

2001 Fares FA

J. Biol. Chem.,Feb 2001; 276:4543 - 4548

Engineering aPotentialAntagonist ofHuman Thyrotropinand Thyroid-stimulating Antibody

custompeptide

were purchased from New EnglandBioLabs (Beverly, MA).Oligonucleotides used for chimericconstruction were purchased fromGenemed Biotechnology (SanFrancisco, CA). Cell culture mediaand reagents were obtained fromBiological Industries (Beit hemeek, Is

2001 Subklewe M

J. Exp. Med.,Feb 2001; 193:405 - 412

Dendritic CellsCross-presentLatency GeneProducts fromEpstein-BarrVirus–transformedB Cells and ExpandTumor-reactiveCD8+ Killer T Cells

custompeptide

......Peptide Loading of DCs. Thesynthetic peptides FLRGRAYGL(HLA-B8+/EBNA 3A) andCLGGLLTMV (HLA-A2/LMP 2) werepurchased from GenemedSynthesis or Research Genetics,and added to APCs and targets at 1MM in RPMI 1640 for 1 h at 37C. TCell Assays. IF

2001 Li JS-Y

J. Immunol., Feb2001; 166: 1855 - 1862

Outer MembraneProtein-SpecificMonoclonalAntibodies ProtectSCID Mice fromFatal Infection bythe ObligateIntracellularBacterial Pathogen

custompeptide

......Peptides were adsorbed insodium carbonate buffer (pH 9.6), ata concentration of 10 Mg/ml. Thepeptides were synthesized byGenemed Synthesis (South SanFrancisco, CA; peptide 61-90), or bythe Wadsworth Center PeptideSynthesis Core Facility. The

2001 Vasile E

FASEB J, Feb2001; 15: 458 -466

Differentialexpression ofthymosin ß-10 byearly passage andsenescent vascularendothelium ismodulated byVPF/VEGF:evidence forsenescent

custompeptide

carboxyl-terminal thymosin b-10specific peptide TIEQEKRSEIS wassynthesized, coupled to keyholelimpet hemocyanine (KLH)(Genemed Synthesis Inc, SanFrancisco, Calif.) and injected intoNew Zealand White rabbits(Lampire Biological Laboratories,Pipersvi

2001 Martin MM

Mol. Endocrinol.,Feb 2001; 15:281 - 293

Human AngiotensinII Type 1 ReceptorIsoforms Encodedby Messenger RNASplice Variants AreFunctionally Distinct

custompeptide

......facilitate cross-linking ofhemocyanin. Rabbits wereimmunized with this conjugatedpeptide using a standardimmunization protocol (GenemedBiotechnologies, Inc., SanFrancisco, CA). Peptide-specificantibody (designated anti-longhAT1R) was obtain

2001 Chang N-S

J. Biol. Chem.,Jan 2001; 276:3361 - 3370

HyaluronidaseInduction of a WWDomain-containingOxidoreductaseThat EnhancesTumor NecrosisFactor Cytotoxicity

custompeptide

......construct 18) (see Table ).Antibody Production A WOX1peptide(RLAFTVDDNPTKPTTRQRY,amino acids 89-107) wassynthesized by GenemedBiotechnologies, Inc. (SanFrancisco, CA) and conjugated withkeyhole limpet hemocyanin forantibody production in r

2001 Pal S

J. Biol. Chem.,Jan 2001; 276:2395 - 2403

Role of ProteinKinase C in Ras-mediatedTranscriptionalActivation ofVascularPermeabilityFactor/VascularEndothelial GrowthFactor Expression

custompeptide

......received from Alex Toker as agenerous gift (). All PKColigonucleotides were synthesizedas phosphorothioate derivativesfrom Genemed Synthesis (SanFrancisco, CA) (). Northern BlotAnalysis RNA, isolated by the single-step acid-phenol extraction

2001 Balaban N

J. Biol. Chem.,Jan 2001; 276:2658 - 2667

Regulation ofStaphylococcusaureusPathogenesis viaTarget of RNAIII-activating Protein(TRAP)

custompeptide

21-kDa Protein Early exponentialwild type S. aureus cells wereincubated for 40 min in the presenceof RAP , synthetic RIP (GenemedSynthesis, Inc. CA), or PBS only asa control. Cells were collected, RNApurified, and Northern blotted, andmembranes wer

2001 Doyle TC

Biophys. J., Jan2001; 80: 427 -434

TryptophanFluorescence ofYeast ActinResolved viaConservedMutations

custompeptide

......Escherichia coli. Transformantsshowing restriction digestscorresponding to mutated residueswere confirmed by dideoxy-sequencing (GeneMed Inc, SanFrancisco, CA). Multiple tryptophanmutations were made by repeatingthe above mutagenic strategy w

2001FonteneauJF

Journal ofImmunologicalMethods,Volume 258,Issues 1-2, 1December 2001,

Generation of highquantities of viraland tumor-specifichuman CD4+ andCD8+ T-cell clonesusing peptide

custompeptide

gp100Ž209 – 217. ŽITDQVPFSV,HLA-A) 0201. and InfluenzaHAŽ307 – 319.ŽPKYVKQNTLKLAT, HLA-DRb1) 0401.

2001 Wei W-Z

Journal ofImmunologicalMethods,Volume 258,Issues 1-2, 1December 2001,Pages 141-150

Foreign antigenicpeptides deliveredto the tumor astargets of cytotoxicT cells

custompeptide

Beta-galactosidase Žb-gal. peptidep876 TPHPARIGLand PADRE aKŽX.VAAWTLKAAaŽa isD-alanine and X is cyclohexylalanine.

2001 Yuan C

Journal ofMolecularBiology, Volume314, Issue 3, 30November 2001,Pages 563-575

Solution structuresof two FHA1-phosphothreoninepeptide complexesprovide insight intothe structural basisof the ligand

custompeptide

All the pT, pS, and pYpeptides were purchased fromGenemed Synthesis

2001 Byeon I-JL


Solution structureof the yeast Rad53FHA2 complexedwith aphosphothreoninepeptide pTXXL:comparison with

custompeptide purified Rad9-derived pT peptides

2001 Gavigan CS

Molecular andBiochemicalParasitology,Volume 117,Issue 1, 28

The role ofaminopeptidases inhaemoglobindegradation inPlasmodium

custompeptide

2001 Ding JL

Volume 759,Issue 2, 15August 2001,Pages 237-246

High-performanceaffinity capture-removal of bacterialpyrogen fromsolutionsJournal ofChromatography B:

custompeptide

S3d (NH -HAEHKVKIKVKQKYGQFPQGTEV-centrations, and injected into theflow cell at a rate of 2TYTCSGNYFLM-COOH)

2001CastellanosMR

Critical ReviewsinOncology/Hematology, Volume39, Issues 1-2,

A rapid method toidentify cytotoxic T-lymphocyte peptideepitopes from HLA-A2 (+) donors

custompeptide peptides from HPV-18 E7

2001 Park B

Immunity,Volume 15,Issue 2, August2001, Pages 213-224

The TruncatedCytoplasmic Tail ofHLA-G Serves aQuality-ControlFunction in Post-

custompeptide KIPAQFYIL; KGGAQFYIL

2001 Zhao Y

Journal ofImmunologicalMethods,Volume 254,

Chemicalengineering of cellpenetratingantibodies

custompeptide

scrambled human C3d 16merpeptide

2001 Woodle MC

Journal ofControlledRelease, Volume74, Issues 1-3, 6

Sterically stabilizedpolyplex: ligand-mediated activity

custompeptide

prototype peptide ligand -ACRGDMFGCA

2001 Tian H

InternationalImmunopharmacology, Volume 1,Issue 4, April2001, Pages 763-

HIV epitope-peptides inaluminum adjuvantinduced high levelsof epitope-specific

custompeptide

2001 Wang LL

Neuroscience,Volume 103,Issue 1, 28February 2001,Pages 143-151

Fos protein isrequired for the re-expression ofangiotensin II type1 receptors in thenucleus tractus

custompeptide

PCR primers used for AT1R, AT2R,c-fos or GADPHin the PCRs

2001 Arnold S

FEBS Letters,Volume 490,Issues 1-2, 9February 2001,Pages 70-74

The role of aproline-inducedbroken-helix motifin α-helix 2 ofBacillus

custompeptide oligonucleotides

2001 Dong X-N

ImmunologyLetters, Volume75, Issue 2, 1January 2001,Pages 149-152

ELNKWA-epitopespecific antibodiesinduced by epitope-vaccine recognizeELDKWA- andother two

custompeptide

2001ArmstrongCE

The Journal ofPhysiology,Volume 536,Issue 1: 49-65.doi:

Rapidly inactivatingand non-inactivating calcium-activatedpotassium currents

custompeptide

19 amino acid ‘ball’ peptide(MFIWTSGRTSSSYRHDEKR)

2001 Suen J-LImmunol; 103:301-309

Characterization ofself-T-cell responseand antigenicdeterminants ofU1A protein withbone marrow-

custompeptide

ovalbumin (OVA)323-339and the histidine TAG controlpeptide (32 amino acids)

2001 Berson JF

Mol. Biol. Cell,Nov 2001; 12:3451 - 3464

Pmel17 InitiatesPremelanosomeMorphogenesiswithinMultivesicularBodies miscl

......peptide (CPIGENSPLLSGQQV-CO2H) corresponding to thecarboxy-terminal 15 residues ofhuman Pmel17. The antiserum wasgenerated by Genemed Synthesis(San Francisco, CA) and affinitypurified with the use of SulfoLinkbeads ( Pierce , Rockford, IL) co

2001Vieira-da-Motta O

Peptides,Volume 22,Issue 10,October 2001,

RNAIII inhibitingpeptide (RIP)inhibits agr-regulated toxin miscl

2002 Cyr JL

J. Neurosci., Apr2002; 22: 2487 -2495

Myosin-1c Interactswith Hair-CellReceptors throughIts Calmodulin-Binding IQ Domains


anti-Myo1c antibody ,IQ1(residues698-720;CRKHSIATFLQARWRGYHQRQKFL), IQ2 (residues 721-743;CHMKHSAVEIQSWWRGTIGRRKAA), and IQ3 (residues 744-766;CKRKWAVDVVRRFIKGFIYRNQPR) peptides

2002 Hulme JT

J. Biol. Chem.,Feb 2002; 277:4079 - 4087

A Novel LeucineZipper TargetsAKAP15 and CyclicAMP-dependentProtein Kinase tothe C Terminus ofthe Skeletal Muscle


Monoclonal anti-Myc antibody ,AKAP15LZ(38-54) andAKAP15LZM(38-54) peptides, AP2peptide

2002 Xu G

J. Biol. Chem.,Dec 2002; 277:49989 - 49997

PTP1B Modulatesthe Association of -Catenin with N-cadherin throughBinding to anAdjacent andPartially


anti-N-cadherin antibody NCD-2,Anti-phosphotyrosine (PY20)monoclonal antibody , Anti-PTP1Bantibodies Anti-beta-cateninantibodies , HRP1-conjugatedsecondary antibodies

2002KedishviliNY

J. Biol. Chem.,Aug 2002; 277:28909 - 28915

Evidence That theHuman Gene forProstate Short-chainDehydrogenase/Reductase (PSDR1)

customantipeptideantibodies RalR1 Monoclonal Antibody

2002 Chatterjee A

J. Bacteriol., Aug2002; 184: 4089 - 4095

RsmA and theQuorum-SensingSignal, N-[3-Oxohexanoyl]- L-HomoserineLactone, Controlthe Levels of rsmB

customantipeptideantibodies anti-RsmA antiserum

2002 Xu G

Clin. CancerRes., Aug 2002;8: 2605 - 2611

HumanCarboxylesterase 2Is CommonlyExpressed inTumor Tissue andIs Correlated withActivation ofIrinotecan


CES2, peroxidase-conjugateddonkey antirabbit IgG ,reagents(Dewax, peroxide block, powerblock, link, horseradish peroxidase,3,3'-diaminobenzidinetetrahydrochloride, hematoxylin, andbuffers)

2002 Liu H-Y

J. Biol. Chem.,Jul 2002; 277:26046 - 26056

ShcB and ShcCActivation by theTrk Family ofReceptor TyrosineKinases


anti-hemagglutinin (HA) antibody,Anti-c-Myc antibodies , Monoclonalanti-Trk antibodies (MCTrks), Rabbitantiserum CH1 domain -ShcB(amino acids 310-477) (namely anti-ShcB GP),rabbit antibodies to Grb2,N-Shc (ShcC), mouse monoclonalantibody to Src (M

2002 Chen K

Mol. Biol. Cell,Jun 2002; 13:1953 - 1964

Pink-eyed DilutionProtein Controls theProcessing ofTyrosinase


Antibodies alpha Pep7 and alphaPep1 polyclonal antibody alphaPep13 , anti-V5 antibody

2002TompkinsSM

J. Immunol; 168:4173 - 4183

De Novo CentralNervous SystemProcessing ofMyelin Antigen IsRequired for theInitiation of


anti-class I and anti-class II Abs(M1/42 and M5/114), MOG35–55 ,PLP 178–191

2002 Gestl SA

Am. J. Pathol.,Apr 2002; 160:1467 - 1479

Expression ofUGT2B7, a UDP-Glucuronosyltransferase Implicated inthe Metabolism of 4-Hydroxyestroneand All-TransRetinoic Acid, inNormal Human

customantipeptideantibodies UGT2B7 Antibody

2002 Gu Y

J. Biol. Chem.,Jan 2002; 277:2275 - 2286

Prion Peptide 106-126 Modulates theAggregation ofCellular PrionProtein andInduces theSynthesis ofPotentiallyNeurotoxic


Anti-PrP monoclonal antibody 3F4(specific to PrP residues 109-112),Anti-PrP monoclonal antibody 8H4,neurofilament-specific (NF68)antibodies , Biotin-tagged PrP106-126 and biotin-tagged scrambledPrP106-126

2002 Elkins CA

J. Bacteriol., Dec2002; 184: 6490 - 6498

SubstrateSpecificity of theRND-TypeMultidrug EffluxPumps AcrB andAcrD of Escherichia

CustomOligo/DNA

Oligonucleotide primers ,mutagenesis techniques ,antimicrobial agents

2002 Zeng H

J. Biol. Chem.,Nov 2002; 277:46791 - 46798

KDR StimulatesEndothelial CellMigration throughHeterotrimeric GProtein Gq/11-mediated Activation

CustomOligo/DNA

Mouse monoclonal antibodies,rabbit polyclonal antibody, Anti-phosphotyrosine antibody , Anti-phospho-p42/p44 MAPK antibodies ,

2002SherwoodAL

Glycobiology,Oct 2002; 12:599 - 606

A highly conservedHis-His motifpresent in 13/4fucosyltransferases is required foroptimal activity andfunctions inacceptor binding

CustomOligo/DNA

DNA sequencing kit , COS-7 cells ,rabbit IgG-agarose beads, andDEAE-Dextran ,Plasmid pCR2.1TOPO , pPROTA and pPROTA-FucT-IV (long form, amino acids58–405) plasmids , GDP-[14C]fucose (283 mCi/mmol) and[35S]dATP,

2002 DeTure MA

J. Biol. Chem.,Sep 2002; 277:34755 - 34759

In Vitro Assemblyof Alzheimer-likeFilaments. HOW ASMALL CLUSTEROF CHARGEDRESIDUES IN TauAND MAP2

CustomOligo/DNA

T4 DNA ligase, Taq DNApolymerase, and chloramphenicol,DNase, and isopropyl--thiogalactopyranoside ,pETh-3bvector, pBR-322

2002 Callahan MK

J. Biol. Chem.,Sep 2002; 277:33604 - 33609

DifferentialAcquisition ofAntigenic Peptidesby Hsp70 and

CustomOligo/DNA Hsp70 cDNA ,

2002 Chan JTH

Hypertension,Sep 2002; 40:335 - 341

AugmentedUpregulation by c-fos of AngiotensinSubtype 1 Receptorin Nucleus TractusSolitarii of

CustomOligo/DNA

GAPDH mRNA , 100-bp DNAmarker

2002 Ahmad S

J. Clin.Microbiol., Jul2002; 40: 2483 -2489

Seminested PCRfor Diagnosis ofCandidemia:Comparison withCulture, AntigenDetection, and

CustomOligo/DNA 5.8S rDNA , 28S rDNA

2002 Li N

Am J PhysiolRenal Physiol,Jun 2002; 282:1111 - 1119

Production ofsuperoxide throughNADH oxidase inthick ascending

CustomOligo/DNA ......plasmid DNA

2002 Horowitz A

J. Cell Biol., May2002; 157: 715 -725

Fibroblast growthfactor–specificmodulation ofcellular response

CustomOligo/DNA

Syndecan-4 cDNA ,Syntheticsyndecan-4 cytoplasmic tail peptides

2002 Sijwali PS

J. Biol. Chem.,Apr 2002; 277:14910 - 14915

Folding of thePlasmodiumfalciparum CysteineProtease Falcipain-2 Is Mediated by aChaperone-likePeptide and Not theProdomain

CustomOligo/DNA

Vent DNApolymerase,Benzyloxycarbonyl-Phe-Arg-7-amino-4-methyl coumarin (Z-Phe-Arg-AMC)1, Z-Leu-Arg-AMC ,Z-Phe-Arg-fluoromethyl ketone (Z-Phe-Arg-FMK) , Oligonucleotides

2002Beltran-Pena E

PhysiologiaPlantarum,Volume 115,Issue 2: 291-297. doi:

Auxin stimulates S6ribosomal proteinphosphorylation inmaize therebyaffecting protein

CustomOligo/DNA synthesized amino acid sequence

2002 Chen C

PNAS, Dec2002; 99: 17072 - 17077.

Reduced sodiumchannel density,altered voltagedependence ofinactivation, andincreasedsusceptibility to

custompeptide β2-ec peptide

2002 Du CJ. Exp. Med;196:1639 - 1644

ChlamydiapneumoniaeInfection of theCentral NervousSystem Worsens

custompeptide

(MOG) peptide (p35–55:MEVGWYRSPFSRVVHLYRNGK)

2002 Brdicka T

J. Exp. Med.,Dec 2002; 196:1617 - 1626

Non–T CellActivation Linker(NTAL): ATransmembraneAdaptor ProteinInvolved in

custompeptide

Human T, B, NK cells, andmonocytes , PE-conjugated mAbs, unlabeled CD56 mAb MEM-188 ,IgM mAb C305, CD28 (IgM mAb248, mouse mAb,

2002 Shirvan A

J. Biol. Chem.,Dec 2002; 277:49799 - 49807

Anti-semaphorin 3AAntibodies RescueRetinal GanglionCells from CellDeath following

custompeptide

Polyclonal anti-Sema3A antibodies,Sema3A-derived peptides

2002 Stultz CM

J. Biol. Chem.,Nov 2002; 277:47653 - 47661

Phosphorylation-inducedConformationalChanges in aMitogen-activatedProtein KinaseSubstrate.

custompeptide Op and pW peptides ,

2002 Deng FM

J. Cell Biol., Nov2002; 159: 685 -694

Uroplakin IIIb, aurothelialdifferentiationmarker, dimerizeswith uroplakin Ib as

custompeptide

Three peptides, (1)VLDRHSSAADTVW, (2)TNSRGSPQAETRWSD, and (3)EPGLERFPSLSP , p35 cDNA

2002 Kelleher SL

J. Nutr., Nov2002; 132: 3280 - 3285

Zinc Transportersin the RatMammary GlandRespond toMarginal Zinc and

custompeptide Peptides ZnT-1, ZnT-2 and ZnT-4.

2002 Chen Y-C

Microbiology,Nov 2002; 148:3743 - 3754

Differentialsecretion ofSap4–6 proteins inCandida albicans

custompeptide

Sap4-, Sap5- and Sap6-specificantibodies

2002 Kohm APJ. Immunol;169:4712 - 4716

Cutting Edge:CD4+CD25+Regulatory T CellsSuppress Antigen-SpecificAutoreactiveImmuneResponses and

custompeptide MOG35–55-specific T cells

2002Prokhnevsky AI

J. Virol., Nov2002; 76: 11003 - 11011

Interaction betweenLong-DistanceTransport Factorand Hsp70-RelatedMovement Protein

custompeptide

p20(CELDKSGGELEILTFSKNEVFL,BYV cDNA

2002 Embers ME

J. Virol., Oct2002; 76: 9798 -9805

Protective Immunityto Rabbit Oral andCutaneousPapillomavirusesby Immunizationwith Short Peptides

custompeptide

peptides: CRPV L2.1, CRPV L2.2,ROPV L2.1, and ROPV L2.2., HPV16 L2 peptide

2002 Feng Y-H

PNAS, Sep2002; 99: 12049 - 12054

G -independentconstitutiveassociation of G swith SHP-1 andangiotensin IIreceptor AT2 isessential in AT2-mediated ITIM-independent

custompeptide

monoclonal anti-c-Myc antibody ,monoclonal anti-hemagglutinin (HA)antibody , monoclonal anti-1D4antibody , oligonucleotides, G alphaprotein peptides , Ang II and[Sar1]Ang II , Rat AT2 receptorgene and synthetic rat AT1 receptorgene

2002 Cazzamali G

PNAS, Sep2002; 99: 12073 - 12078

Molecular cloningand functionalexpression of thefirst insectFMRFamidereceptor

custompeptide

Peptides (D. melanogasterFMRFamides 1–8; drostatins-A4, -B2, -C; D. melanogastermyosuppressin; D. melanogastershort neuropeptide F1; D.melanogaster tachykinin-3; and D.melanogaster adipokinetichormone), (FMRFamide, D.melanogaster crustacean cardio

2002Cormet-Boyaka E

PNAS, Sep2002; 99: 12477 - 12482

CFTR chloridechannels areregulated by aSNAP-23/syntaxin

custompeptide SNAP-23 antibody ,

2002 Harada JN

J. Virol., Sep2002; 76: 9194 -9206

Analysis of theAdenovirus E1B-55K-AnchoredProteome RevealsIts Link toUbiquitinationMachinery

custompeptide

SIII p15 monoclonal antibody ,Rbx1/ROC1/Hrt1 rabbit polyclonalantibody , Cullin-5 antibodies ,Elongin B antibody , monoclonalNuMA and anti-E-MAP-115/ensconsin (guinea pig)antibodies , M45 mousemonoclonal antibody , E32 rabbitantipeptide antiseru

2002 Zhang X

J. Virol., Sep2002; 76: 8737 -8746

Identification andCharacterization ofa RegulatoryDomain on theCarboxyl Terminus

custompeptide MBP peptide , p53 peptide

2002 Baba O

J. Histochem.Cytochem., Sep2002; 50: 1229 -1236

Expression ofAlternativelySpliced RNATranscripts ofAmelogenin GeneExons 8 and 9 and

custompeptide

peptide (RHPLNMETTTEK) , 156-bp rat cDNA , DIG RNA Labeling Kit

2002 Chen C-W

J. Biol. Chem.,Aug 2002; 277:33058 - 33067

The Double-stranded RNA-activated Kinase,PKR, CanPhosphorylateHepatitis D Virus

custompeptide

rabbit antiserum against Ser177-phosphorylated S-HDAg peptide

2002Peherstorfer E

Am J PhysiolRenal Physiol,Jul 2002; 283:190 - 196

Effects ofmicroinjection ofsynthetic Bcl-2domain peptides onapoptosis of renal

custompeptide

Synthetic peptides. Bcl2_syn,Bax_syn, and Bak_syn

2002 Hu J

J. Virol., Jul2002; 76: 6453 -6459.

IntracutaneousDNA Vaccinationwith the E8 Gene ofCottontail RabbitPapillomavirusInduces Protective

custompeptide

Peptide 1 (MGPAETALYC; aa 1 to10) and peptide 2(RKYLAGSCVVQFAEEDC; aa 35 to50)

2002 Gierynska MJ. Virol; 76: 6568- 6576

Induction of CD8 T-Cell-SpecificSystemic andMucosal Immunityagainst HerpesSimplex Virus with

custompeptide

peptide HSVgB (amino acids [aa]498 to 505), peptide SSIEFARL, andchicken egg ovalbumin (aa 257 to264), monoclonal antibodies (MAb)

2002 Shih S-C

Am. J. Pathol.,Jul 2002; 161: 35- 41

Molecular Profilingof AngiogenesisMarkers

custompeptide

sequence of choice was checked byNational Center for BiotechnologyInformation (NCBI) Blast moduleand was synthesized by GenemedSynthesis (South San Francisco,CA). To assure the specificity ofeach primer set, ampliconsgenerated from PCR reactions we

2002 Fong Y

Science, Jun2002; 296: 2235 - 2238

Regulation of theDifferent ChromatinStates ofAutosomes and XChromosomes in

custompeptide Anti-MES-4 antibodies

2002Uettwiller-Geiger D

Clin. Chem., Jun2002; 48: 869 -876

MulticenterEvaluation of anAutomated Assay

custompeptide synthetic peptides cTnI

2002 Murakami M

J. Biol. Chem.,May 2002; 277:20367 - 20371

Protein Kinase C(PKC) RegulatesPKC Activity in aSyndecan-4-dependent Manner

custompeptide

PKC beta1 optimal substratepeptide (FKLKRKGSFKKFA), c-Myc antibody , PKCalpha antibodies,

2002 Balicki D

PNAS, May2002; 99: 7467 -7471

Structure andfunction correlationin histone H2Apeptide-mediated

custompeptide Peptides 1-8, Peptides 11-14 ,

2002 Roberts WK

Blood, May2002; 99: 3748 -3755

Vaccination withCD20 peptidesinduces abiologically active,

custompeptide CD20 and P190 control peptides

2002 Kawa DE

J. Immunol., May2002; 168: 5184 - 5191

Antigenic Topologyof Chlamydial PorBProtein andIdentification ofTargets for Immune

custompeptide

PorB peptides (designated B1-1 toB5-5),

2002 Burgess HA

J. Biol. Chem.,May 2002; 277:17696 - 17705

Alternative SpliceVariants ofDoublecortin-likeKinase AreDifferentiallyExpressed andHave DifferentKinase Activities

custompeptide

anti-DCLK Arg domain antibodies,peptide (CLGRRHSLQRGWR), anti-DCLK phospho-Ser-382 antibodies, peptide (CLGRRHSLQRGWR ,Anti-DCLK phospho-Ser-382antibodies , anti-tubulin monoclonalantibody , peroxidase-conjugatedaffinity pure goat anti-mouse IgG

2002 Jeon S

J. Biol. Chem.,May 2002; 277:16576 - 16584

RhoA and RhoKinase-dependentPhosphorylation ofMoesin at Thr-558in Hippocampal

custompeptide

moesin polyclonal antibody ,antibody TM2, phosphopeptide(KYKpTLRQCCCCC, where pT isphosphothreonine)

2002 Chan SHH

Mol. Pharmacol.,May 2002; 61:1097 - 1104

Up-Regulation ofGlutamateReceptors inNucleus TractusSolitarii UnderliesPotentiation ofBaroreceptorReflex by HeatShock Protein 70

custompeptide

......Microinjection ofOligonucleotide or Test Agent intothe NTS . An antisense (5-CACCTTGCCGTGCTGGAA-3)oligonucleotide (50 pmol; GenemedBiotechnologies, San Francisco,CA) that targets against the codingregion (nt 61-78) of the mouse heat-inducible

2002 Liu Q-R

J. Biol. Chem.,Apr 2002; 277:13312 - 13320

KEPI, a PKC-dependent ProteinPhosphatase 1Inhibitor Regulated

custompeptide 15-amino acid KEPI peptide

2002 Staubli F

PNAS, Mar2002; 99: 3446 -3451

Molecularidentification of theinsect adipokinetichormone receptors

custompeptide

D. melanogaster AKH (Drm-AKH);Manduca sexta AKH (Mas-AKH);drostatin-A1) ,Heliothis zeahypertrehalosaemic hormone (Hez-HrTH); Schistocerca gregaria AKH-II(Scg-AKH-II); corazonin

2002 Du CJ. Immunol; 168:3105 - 3112

Increased Severityof ExperimentalAllergicEncephalomyelitisin lyn-/- Mice in theAbsence ofElevatedProinflammatory

custompeptide

anti-murine IL-12 mAbs (C17.5 andC15.6), Murine rIL-12 , MOGpeptide (p35-55:MEVGWYRSPFSRVVHLYRNGK)

2002 Hara H

J. Immunol., Mar2002; 168: 2288 - 2295

The ApoptoticProtease-ActivatingFactor 1-MediatedPathway ofApoptosis IsDispensable forNegative Selection

custompeptide

H-Y Ag peptide (sequence Lys-Cys-Ser-Arg-Asn-Arg-Gln-Tyt-Leu ,FITC-conjugated T3.70 mAb, PE-conjugated anti-CD8 mAb,allophycocyanin-conjugated anti-CD8 mAb

2002 Ravi R

Cancer Res.,Mar 2002; 62:1583 - 1587

Requirement ofBAX forTRAIL/Apo2L-induced Apoptosisof ColorectalCancers:Synergism withSulindac-mediatedInhibition of Bcl-xL

custompeptide

......Met; N, Asn; Q, Gln; R, Arg; S,Ser; T, Thr; V, Val; and W, Trp. Bothpeptides were supplied as a 20-mmsolution in DMSO (GenemedSynthesis Inc., South SanFrancisco, CA). Results for DMSOcontrols were not different fromcontrols using no peptide.

2002PastorinoJG

J. Biol. Chem.,Feb 2002; 277:7610 - 7618

MitochondrialBinding ofHexokinase IIInhibits Bax-inducedCytochrome cRelease andApoptosis

custompeptide

......necrosis. Synthesis of PeptidesPeptides corresponding to the N-terminal 15 amino acids ofhexokinase II were synthesized byGenemed Synthesis (SanFrancisco, CA) utilizing Fmoc (N-(9-fluorenyl)methoxycarbonyl)chemistry (MIASHLLAYFFTELN-amide, hex


Biophys. J., Jan2002; 82: 233 -243

The Structure ofthe C-TerminalDomain of the Pro-Apoptotic ProteinBak and ItsInteraction withModel Membranes

custompeptide

synthetic peptide Bak (+3HN-188ILNVLVVLGVVLLGQFVVRRFFKS211-COO) , Deuterium oxide(D2O), 1,6-diphenyl-1,3,5-hexatriene (DPH), and 2,2,2-trifluoroethanol (TFE)

2002 Lee AW

Vaccine, Volume20, Supplement4, 19 December2002, Pages A8-A22

A clinical gradecocktail ofcytokines andPGE2 results inuniform maturationof human

custompeptide

HLA A2.1-positiveDCs were pulsed with 1–100nMHLA A2.1-restricted influenzamatrix peptide;

2002 Chowers MY

FEMSMicrobiologyLetters, Volume217, Issue 2, 17

A defined humangastrin sequencestimulates thegrowth of

custompeptide Gastrin fragments 15-17 and 16-17

2002 Dong X-N

Vaccine, Volume21, Issues 3-4,13 December2002, Pages 167-

Candidate peptidevaccine inducedprotection againstclassical swine

custompeptide

Five overlapped peptides sequence-covering amino acids

2002 Huang J

ImmunologyLetters, Volume84, Issue 3, 3December 2002,Pages 205-209

A predefinedepitope-specificmonoclonalantibody recognizesELDEWA-epitopejust presenting ongp41 of HIV-1 Oclade

custompeptide

ELDEWA epitope-peptide (C-G/ELDEWA/G/ELDEWA); the C-dormain peptideP1 (EnvIIIB, aa.669 /674. C-SQNQQEKNEQELL/ELDKWA/SLWNWFNITC), three peptidesbearing neutralization-resistant mutated epitopesequences, P2 (CQEKNVKALL/ELDEWA/SLWN, according to the

2002 Sauer FG


Chaperone Primingof Pilus SubunitsFacilitates aTopologicalTransition that

custompeptide PapENtdKNte

2002DenBestenPK

Archives of OralBiology, Volume47, Issue 11,November 2002,

Effects of fluorideon rat dentalenamel matrixproteinases

custompeptide peptide (SYGYEPMGGWLHHQ)

2002 Li H

ImmunologyLetters, Volume84, Issue 2, 1November 2002,Pages 153-157

Recombinant multi-epitope vaccineinduce predefinedepitope-specificantibodies againstHIV-1

custompeptide

Threepeptides (P1, P2 and P3) containingneutralizing epitopeson HIV-1IIIB gp160 and controlpeptide (CP); P1: [C-(GPGRAFY)2,Env aa317-323]; P2:[CTSLIHSLIEESQNQQEKNEQELLELDKWA,Envaa646-674]; P3: [C-TRPNNTRKSIRIQRGPGRAFYTIGKI,Env aa301-328]; CP: [(K

2002 Jiménez A

FEBS Letters,Volume 530,Issues 1-3, 23October 2002,Pages 79-84

Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein withoxidizing activity

custompeptide NRCSQGSCWN

2002 Adams JC

Gene, Volume297, Issues 1-2,4 September2002, Pages 69-78

Characterization ofa Drosophilamelanogasterorthologue ofmuskelin

custompeptide

KHL-conjugated synthetic peptideDMK-C, correspondingto residues MVQPERNLSDFVVM ofthe predicted Drosophilamuskelin,

2002 Morgan C

Peptides,Volume 23,Issue 7, July2002, Pages

Laminin affectspolymerization,depolymerizationand neurotoxicity of

custompeptide YIGSR, IKVAV, YFQRYLI

2002 Misra GP

Journal ofControlledRelease, Volume81, Issues 1-2,17 May 2002,

New mode of drugdelivery: long termautonomousrhythmic hormonerelease across a

custompeptide tetramethylrhodamine - GnRH

2002 Lee KJ

Peptides,Volume 23,Issue 5, May2002, Pages 853-862

Antipeptideantibodies fordetecting crab(Callinectessapidus) molt-

custompeptide

acetylated on the N-terminus andcoupled via the C-terminus tokeyhole limpet hemocyanin(KLH) with glutaraldehyde

2002MuilenburgDJ

Enzymology,Volume 1596,Issue 2, 29 April2002, Pages 346-356

Lys40 but notArg143 influencesselectivity ofangiotensinconversion byhuman α-chymaseBiochimica et

custompeptide

5P-ATGCTG CTT CTT CCT CTC CCC CTGCT and reverseprimer 5P-TTA ATT TGC CTG CAGGATCTG GTT GAT CCA GGG.

2002 Meric B

Talanta, Volume56, Issue 5, 1April 2002,Pages 837-846

ElectrochemicalDNA biosensor forthe detection of TTand Hepatitis Bvirus from PCRamplified realsamples by using

custompeptide

24-mer synthetic oligonucleotidesfor theTTV (TTV Probe) and the 21-mersyntheticoligonucleotides of HBV (HBVProbe)

2002 Nah J-W

Journal ofControlledRelease, Volume78, Issues 1-3,17 January 2002,Pages 273-284

Artery wall bindingpeptide-poly(ethyleneglycol)-grafted-poly(-lysine)-basedgene delivery toartery wall cells

custompeptide

Artery Plasmid encoding fireflyluciferase driven by thewall binding peptide (AWBP)(Sequence ‘N’- CMV promoter wasconstructed by insertion ofCGRALVDTLKFVTQAEGAK-‘C’

2002StemmannO

Cell, Volume107, Issue 6, 14December 2001,Pages 715-726

Dual Inhibition ofSister ChromatidSeparation atMetaphase

custompeptide

N-terminal peptide(RSFKRVNFGTLLSSQ) and a C-terminal peptide(EPYSDIIATPGPRFH)

2002 Chowers MY

FEMSMicrobiologyLetters, Volume217, Issue 2:231-236. doi:

A defined humangastrin sequencestimulates thegrowth ofHelicobacter pylori

custompeptide gastrin fragments 15-17 and 16-17

2002Nymann-Andersen J

Journal ofNeurochemistry,Volume 80,Issue 5: 815-823. doi:

Subunit specificityand interactiondomain betweenGABAA receptor-associated protein

custompeptide

peptide inhibition assay, 450 umpeptide,CFEDCRTGAWRHGRIHIRIAKMD

2002 Hallahan D

Cancer Cell,Volume 3, Issue1, January 2003,Pages 63-74

Integrin-mediatedtargeting of drugdelivery toirradiated tumor miscl

FITC-labeled peptide (GenemedSynthesis

2002 Iversen A

Biochemical andBiophysicalResearchCommunications, Volume 299,

Molecularidentification of thefirst insect ecdysistriggering hormonereceptors miscl

2002 Iversen A


Molecular cloningand functionalexpression of aDrosophila receptorfor the miscl

2002 Cazzamali G


Molecular cloningand functionalexpression of aDrosophilacorazonin receptor miscl

2002 Yau HCM

Thin Solid Films,Volume 413,Issues 1-2, 24June 2002,Pages 218-223

Integrity and redoxproperties ofhomogeneous andheterogeneousDNA films on gold miscl

2002Vieira daSilva J

Vaccine, Volume20, Issue 16, 15May 2002,Pages 2091-2101

Phytosecretion ofenteropathogenicEscherichia colipilin subunit A intransgenic tobaccoand its suitability for miscl

2002MUSTAFAAS

Clinical &ExperimentalImmunology,Volume 130,Issue 1: 37-42.doi:10.1046/j.1365-2249.2002.01937.x

Immunogenicity ofMycobacteriumtuberculosis RD1region geneproducts in infectedcattle miscl

The peptides, purchased fromGenemed Synthesis Inc (SanFrancisco, USA), were synthesizedusing Fmoc chemistry; and theirsequence fidelity and purity wasconfirmed by mass spectrometryand analytical HPLC, respectively.

2003 Lee H

J. Immunol., Dec2003; 171: 5802 - 5811

Role ofAntiproliferative BCell TranslocationGene-1 as anApoptotic Sensitizerin Activation-Induced Cell Deathof Brain Microglia


BTG1 cDNA ,LPS, N-monomethyl-L-arginine (NMMA), S-nitroso-N-acetylpenicillamine (SNAP), sodiumnitroprusside (SNP), andtetracycline ,Recombinant mouseIFN--Cyano(3,4-dihydroxy)-N-benzylcinnamide (AG490)

2003 Yokoyama N

J. Biol. Chem.,Nov 2003; 278:47713 - 47723

BiochemicalProperties of theCdc42-associatedTyrosine KinaseACK1:SUBSTRATESPECIFICITY,


Anti-HA monoclonal antibody andanti-ACK and anti-Hck polyclonalantibodies

2003 Elovitz MA

Am. J. Pathol.,Nov 2003; 163:2103 - 2111

A New Model forInflammation-Induced PretermBirth: The Role ofPlatelet-Activating

customantipeptideantibodies PAFR antibody

2003 Liu G

J. Clin. Invest.,Jul 2003; 112:209 - 221

Neph1 and nephrininteraction in the slitdiaphragm is animportantdeterminant of


Neph1 cDNA ,Neph1 peptide ,KLH-conjugated peptides ,

2003 Kong W

J. Biol. Chem.,Jun 2003; 278:22781 - 22786

Molecular Cloningand Expression ofKeratinocyteProline-rich Protein,a Novel SquamousEpithelial MarkerIsolated DuringSkin Development


RNAzol B,FastTrack mRNAisolation kit, superscript II, TAcloning vectors, TA cloning dual-promoter vectors, and ElectroMAXDH5-E cells ,SMART cDNA libraryconstruction kit ,[-32P]dCTP , dCTPlabeling kit , Digoxigenin-RNAlabeling kit , peptide, PCPS

2003 Berson JF

J. Cell Biol., May2003; 161: 521 -533

Proproteinconvertasecleavage liberatesa fibrillogenicfragment of aresidentglycoprotein to


affinity-purified rabbit antibody ,Antibodies mAB, Rabbit antiserumPmel-N, synthetic peptide(CTKVPRNQDWLGVSRQLR-CO2H

2003 Krenz M

J. Biol. Chem.,May 2003; 278:17466 - 17474

Analysis of MyosinHeavy ChainFunctionality in the


Alexa 488-conjugated secondaryantibody ,

2003WedamanKP

Mol. Biol. Cell,Mar 2003; 14:1204 - 1220

Tor Kinases Are inDistinct Membrane-associated ProteinComplexes inSaccharomyces

customantipeptideantibodies Anti-HA polyclonal antibodies ,

2003 Kocher O

Mol. Cell. Biol.,Feb 2003; 23:1175 - 1180

Targeted Disruptionof the PDZK1 Geneby HomologousRecombination

customantipeptideantibodies PDZK1 cDNA

2003 Nichols WK

Toxicol. Sci., Feb2003; 71: 229 -236

3-Methylindole-Induced Toxicity toHuman BronchialEpithelial Cell Lines


antipeptide polyclonal antibodies toCYP2F1 that were produced byGenemed Synthesis, Inc. (SanFrancisco, CA). These antibodieswere...antipeptide polyclonalantibodies to CYP2F1 that wereproduced by Genemed Synthesis,Inc. (San Francisco, CA). These ant

2003 Reed JC

Virology, Volume306, Issue 2, 15February 2003,

Suppressor of RNAsilencing encodedby Beet yellows

customantipeptideantibodies rabbit polyclonal antiserum

2003 Shih S-C

PNAS, Dec2003; 100:15859 - 15864

Transforminggrowth factor 1induction ofvascular endothelialgrowth factorreceptor 1:

CustomOligo/DNA

cDNA VEGFR-1, VEGFR-2, TGF-beta1, VEGF-A

2003 Kulkarni AA

J. Biol. Chem.,Dec 2003; 278:51833 - 51840

Analysis ofTransmembraneSegment 7 of theDipeptideTransporter

CustomOligo/DNA hPepT1 cDNA ,

2003 Leong W-I

Am J PhysiolGastrointestLiver Physiol,Dec 2003; 285:

DMT1 and FPN1expression duringinfancy:developmental

CustomOligo/DNA

DMT1 and FPN1 antibodies,humanDMT1 cDNA ,rat FPN1 cDNA

2003 Ferree S

Biophys. J., Oct2003; 85: 2539 -2546

ElectrokineticStretching ofTethered DNA

CustomOligo/DNA

Lambda bacteriophage DNA ,T4DNA ligase

2003 Cousin SJ

Appl. Envir.Microbiol., Aug2003; 69: 4875 -4883

High-LevelProduction ofPorphyrins inMetabolicallyEngineeredEscherichia coli:SystematicExtension of a

CustomOligo/DNA

Restriction enzymes, T4 DNAligase, and Vent DNA polymerase ,Klenow polymerase , Taq DNApolymerase in buffer A,Oligonucleotide primers ,

2003 Liu A

J. Biol. Chem.,Jul 2003; 278:26423 - 26434

Functional Analysisof the Rat N-Methyl-D-aspartateReceptor 2APromoter:MULTIPLETRANSCRIPTIONSTART POINTS,POSITIVE

CustomOligo/DNA

Antibodies against Sp1, Sp3, andSp4

2003 Shih S-C

J. Clin. Invest.,Jul 2003; 112: 50- 57

Selectivestimulation ofVEGFR-1 preventsoxygen-inducedretinal vascular

CustomOligo/DNA VEGFR-1 and VEGFR-2 mRNA

2003 Zeng H

J. Biol. Chem.,May 2003; 278:20738 - 20745

Heterotrimeric Gq/G 11 ProteinsFunction Upstreamof VascularEndothelial GrowthFactor (VEGF)Receptor-2 (KDR)Phosphorylation inVascular

CustomOligo/DNA

Recombinant VPF/VEGF , EGM-MVBullet kit, trypsin-EDTA, and trypsinneutralization solution , Rabbitpolyclonal antibodies , anti-phosphotyrosine antibody ,antiphospho-p42/p44 MAPKantibody , [3H]thymidine , PluronicF-127

2003 Zhang N

Invest.Ophthalmol. Vis.Sci., May 2003;44: 3441.

MolecularIdentification ofMembranePotential DrivenOrganic CationTransporters in theRabbit ConjunctivalEpithelium

CustomOligo/DNA

QIAquickTM Gel Extraction Kit ,Poly(A)+RNA , Oligotex mRNA MiniKit. mRNA samples (5 mg/lane) ,HRP-labeled 335bp rbOCT3 cDNA,Western blot , polyclonal rabbit anti-rOCT3 antibody

2003 Uemura Y

J. Immunol., Jan2003; 170: 947 -960.

SystematicAnalysis of theCombinatorialNature of EpitopesRecognized byTCR Leads toIdentification ofMimicry Epitopesfor Glutamic AcidDecarboxylase 65-

CustomOligo/DNA

......Briefly, oligonucleotidefragments encoding degenerateGAD65115-127 were synthesizedand purified using polyacrylamidegel (Genemed Synthesis, South SanFrancisco, CA). Theseoligonucleotide fragments wereamplified by PCR with 5-biotinylatedprime

2003 Tehara SK

Appl. Envir.Microbiol., Jan2003; 69: 504 -508

Gene Cloning,Purification, andCharacterization ofaPhosphodiesterasefrom DelftiaacidovoransAppl. Envir.Microbiol., Jan2003; 69: 504 - 508

CustomOligo/DNA

......essentially the sameprocedures outlined for Southernblots. The positive clone pSKT1 wassent for nucleotide sequencing byGenemed Inc. (South SanFrancisco, Calif.) and the DNASequencing Facility at the Universityof California at Berkeley. Phos

2003 Yau HCM

Biosensors andBioelectronics,Volume 18,Issue 7, July2003, Pages 873-879

Electrochemicalproperties of DNA-intercalatingdoxorubicin andmethylene blue onn-hexadecylmercaptan-doped5′-thiol-labeled

CustomOligo/DNA

5-HS-(CH2)6-CAA GTA GCGAAG CGA GCA GGA C-3(abbreviated HS-ssDNA)and it complementary sequence 5-GTC CTG CTCGCT TCG CTA CTT G-3(abbreviated ssDNA).

2003 Zhang X

MaterialsChemistry andPhysics, Volume77, Issue 3, 30

Preparation of CdSnanoparticles onLangmuirmonolayers of

CustomOligo/DNA

OligomericDNAcontaining 10adenine bases (oligo[A]10)

2003 Liu B

PNAS, Dec2003; 100:15824 - 15829

Cell surfaceexpression of anendoplasmicreticulum residentheat shock proteingp96 triggers

custompeptide ApaL I DNA

2003Stevenson-Lindert LM

J. Biol. Chem.,Dec 2003; 278:50956 - 50960.

SubstrateSpecificity of CDK2-Cyclin A: WHAT IS

custompeptide Peptides CDK2-Cyclin A

2003Abdel-Ghany M

J. Biol. Chem.,Dec 2003; 278:49406 - 49416

The InteractingBinding Domains ofthe 4 Integrin andCalcium-activatedChloride Channels(CLCAs) inMetastasis

custompeptide

mouse -human monoclonal antibody(mAb) 3E1 ,rabbit -humanpolyclonal antibody (pAb) H-101 ,rat -mouse mAb346–11A,syntheticpeptides of 4(184–203) and1(207–213).

2003 Leong W-I

Am. J. ClinicalNutrition, Dec2003; 78: 1203 -1211

Ironsupplementationduringinfancy—effects onexpression of iron

custompeptide DMT1 and FPN1 antibodies

2003 Toka FN

J. Virol., Dec2003; 77: 12742 - 12752

Codelivery of CCR7Ligands asMolecularAdjuvantsEnhances theProtective Immune

custompeptide

Peptide HSV-gB498-505(SSIEFARL,Plasmid DNA. CCL19-and CCL21

2003 Verica JA

Plant Physiology,Dec 2003; 133:1732 - 1746

Tissue-Specific andDevelopmentallyRegulatedExpression of aCluster ofTandemly ArrayedCell Wall-

custompeptide

WAK1 cDNA ,WAKL6 polyclonalantibodies

2003 Hastings RH

Am. J. Respir.Cell Mol. Biol.,Dec 2003; 29:733 - 742

ProapoptoticEffects ofParathyroidHormone-Related

custompeptide PTHrP peptides

2003BuscagliaCA

Mol. Biol. Cell,Dec 2003; 14:4947 - 4957

Sites of Interactionbetween AldolaseandThrombospondin-related Anonymous

custompeptide Peptides P. falciparum TRAP

2003 Sohn J

J. Biol. Chem.,Nov 2003; 278:47868 - 47876

Orientation ofFollicle-stimulatingHormone (FSH)SubunitsComplexed with theFSH Receptor:SUBUNITTOWARD THE N

custompeptide FSHR cDNAs ,

2003 Bennett RJ

Mol. Cell. Biol.,Nov 2003; 23:8189 - 8201

Identification andCharacterization ofa Candida albicansMating Pheromone

custompeptide Cy3-cDNA and Cy5-cDNA

2003 Solomon J

J. Bacteriol., Nov2003; 185: 6425 - 6433.

Isolation andCharacterization ofMutants of theBacillus subtilisOligopeptidePermease with

custompeptide CSF pentapeptide ERGMT (37

2003 Kelleher SL

J. Nutr., Nov2003; 133: 3378 - 3385

Zn TransporterLevels andLocalizationChangeThroughoutLactation in Rat

custompeptide peptide Zip3

2003 Marian CO

Plant Physiology,Nov 2003; 133:1336 - 1350

The Maize Singlemyb histone 1Gene, Smh1,Belongs to a NovelGene Family andEncodes a Protein

custompeptide Smh1 cDNA

2003 Ikonen M

PNAS, Oct 2003;100: 13042 -13047

Interaction betweenthe Alzheimer'ssurvival peptidehumanin andinsulin-like growthfactor-bindingprotein 3 regulatescell survival andapoptosis

custompeptide

A (1–43) peptide ,HN peptides [HN,S14G-HN (HNG), C8A-HN (HNA),F6A-HN, K21A-HN, and F6/K21A-HN],Recombinant human IGFBP-3and IGFBP-3 peptides ,anti-humanIGFBP-3 antibody ,Rabbit polyclonalanti-HN antibody

2003 Hulme JT

PNAS, Oct 2003;100: 13093 -13098

-Adrenergicregulation requiresdirect anchoring ofPKA to cardiacCaV1.2 channelsvia a leucine zipperinteraction with A

custompeptide

HT31 peptide,AKAP15LZ(38-54)(acetyl-ENAVLKAVQQYLEETQN-amide) and AKAP15LZM(38-54)peptides ,polyclonal anti-CNC1 andanti-CH1 antibodies ,Anti-RIIantibody ,Anti-AKAP15 antibodies

2003 Woo S-H

J. Physiol., Oct2003; 552: 437 -447

Modulation of Ca2+signalling in ratatrial myocytes:possible role of the

custompeptide LA-, K- and LM1-peptides

2003 Schroers R

Clin. CancerRes., Oct 2003;9: 4743 - 4755.

Human TelomeraseReverseTranscriptase-Specific T-HelperResponsesInduced byPromiscuous Major

custompeptide

peptide EBNA482(AEGLRALLARSHVER)

2003Gaynutdinov TI

drug deliveryProtein Eng., Oct2003; 16: 771 -775

Chimericribonuclease as asource of humanadapter protein for

custompeptide

Hu-peptide (CA-KESRAKKFQRQHMDS

2003 Licht TBlood, Sep 2003;102: 2099 - 2107

Induction of pro-angiogenicsignaling by asynthetic peptidederived from the

custompeptide

Six peptides ,polyclonal anti-ERK2antibody

2003 Harms GS

Biophys. J., Sep2003; 85: 1826 -1838

ProbingConformationalChanges ofGramicidin IonChannels by Single-

custompeptide Dye labeling

2003 Chang H-C

J. Biol. Chem.,Aug 2003; 278:32471 - 32477

STAT4 Requiresthe N-terminalDomain for EfficientPhosphorylation

custompeptide

phosphopeptideDLPTHDGpY800LPSNIDD and theidentical non-phosphorylated peptide

2003 Egerod K

PNAS, Aug2003; 100: 9808 - 9813

Molecular cloningand functionalexpression of thefirst two specificinsectmyosuppressinreceptors

custompeptide

TRIzol Reagent ,DNA-free kit,SMART RACPeptides,E cDNAAmplification Kit Northern blots,LASERGENE software package(DNASTAR). ,TMHMM v.2.0prediction server ,PRISM v.3software

2003 Gong S

J. Bacteriol., Aug2003; 185: 4402 - 4409

YjdE (AdiC) Is theArginine:AgmatineAntiporter Essentialfor Arginine-Dependent AcidResistance in

custompeptide

peptide CLHKNPYPLDAPISKD,AdiA antibody ,Western blot,Northern blot

2003 Cousin MA

J. Biol. Chem.,Aug 2003; 278:29065 - 29071

Synapsin I-associatedPhosphatidylinositol3-Kinase MediatesSynaptic VesicleDelivery to theReadily ReleasablePool

custompeptide

p85 antibody,synapsin I antibody,polyclonal synapsin antibody ,Synthetic peptides Syn I539–553GAPPAARPPASPSPQ, SynI566–577 SISGPAPPKVSG, andSyn I585–600RQGPPQKPPGPAGPIR,SynI585–600 peptide (RRMKWKK-RQGPPQKPPGPAGPIR) or -adaptin AP-2 2624_644 (RRMKW

2003 Cousin J-H

Carcinogenesis,Aug 2003; 24:1301 - 1315

Roles ofkeratinocyteinflammation in oralcancer: regulatingthe prostaglandinE2, interleukin-6and TNF-production of oralepithelial cells byareca nut extract

custompeptide

Mouse anti-human COX-2monoclonal antibody,Protein assaykits ,Phycoerythrin-conjugated anti-human CD4+ and CD8+ and FITC-conjugated anti-human CD69+ ab,IgG (isotype control) and flowcytometric reagents ,ab for 1-FITC/1-PE ,ELISA kits for TNF- (ultrase

2003 Schroers R

Clin. CancerRes., Aug 2003;9: 3260 - 3271

Identification ofMHC Class II-restricted T-cellEpitopes inProstate-specificMembrane Antigen

custompeptide

six peptides [PSMA17(RPRWLCAGALVLAGGFFLLGF),PSMA100 (WKEFGLDSVELAHYD),PSMA206 (GKVFRGNKVKNAQLA),PSMA459 (NYTLRVDCTPLMYSL),PSMA576(VAQVRGGMVFELANSIVLPFD),and PSMA730(RQIYVAAFTVQAAAE)] ,PeptideEBNA482(AEGLRALLARSHVER),HLA-DR-binding peptides TEPIT

2003 Chen Y-M

Biol Reprod, Aug2003; 69: 656 -672

Fer Kinase/FerTand AdherensJunction Dynamicsin the Testis: An InVitro and In VivoStudy

custompeptide

21-amino acid peptide (NH2-SAPQNCPEEIFTIMMKCWDYK-COOH) ,Primary antibodies againstN-cadherin (H-63; Cat: SC-7939,Lot: C081), E-cadherin (H-108; Cat:SC-7870, Lot: K080), -catenin (Cat:SC-7900, Lot: J139), p120ctn (S-19;Cat: SC-1101, Lot: A079), actin

2003 Liu JA

J. Immunol., Jul2003; 171: 538 -541

Cutting Edge: TheConversion ofArginine toCitrulline Allows fora High-AffinityPeptide Interactionwith theRheumatoidArthritis-AssociatedHLA-DRB1*0401MHC Class II

custompeptide

Peptides P4D, human aggrecanpeptide 280–292,AGWLADRSVRYPI; P4R, alteredhuman aggrecan peptide 280–292,AGWLARRSVRYPI; and P4citrulline(Cit), altered human aggrecanpeptide 280–292,AGWLACitRSVRYPI, Peptidesvimentin (Vim)65–77, humanvimentin peptide

2003 Warren DPNAS, Jul 2003;100: 8176 - 8181

Identification of theintegrase surfacethat interacts withXis reveals aresidue that is also

custompeptide

Peptides lambdaXis(TGGLLKRIRNGKK)

2003 Lee W-S

J. Biol. Chem.,Jul 2003; 278:25940 - 25946

Small ConductanceCa2+-activated K+Channels andCalmodulin: CELLSURFACE

custompeptide SK-MLCK M13 peptide

2003 Kelleher SL

J. Nutr., Jul2003; 133: 2141 - 2148

Marginal MaternalZn Intake in RatsAlters MammaryGland CuTransporter Levelsand Milk Cu

custompeptide Peptide rat Atp7A ,rat Atp7B

2003 Beisner DRJ. Immunol; 171:247 - 256

The Requirementsfor Fas-AssociatedDeath DomainSignaling in MatureT Cell Activation

custompeptide OVA peptide

2003 Li L

J. Immunol., Jul2003; 171: 390 -397

Mast Cells inAirwayHyporesponsiveC3H/HeJ MiceExpress a UniqueIsoform of theSignaling ProteinRas Guanine

custompeptide

V5 and 6xHis peptides12-merpeptide Arg-Lys-Asp-Ile-Lys-Arg-Lys-Ser-His-Gln-Glu-Cys anti-mRasGRP4 Abs

2003 Fischer D

J. Virol., Jul2003; 77: 7486 -7491

IntranasalImmunization ofGuinea Pigs withanImmunodominantFoot-and-MouthDisease Virus

custompeptide

14-mer peptide (amino acidsequence C-G-Y-G-P-P-K-K-K-A-K-V-G-G

2003 Kim HPNAS, Jun 2003;100: 7460 - 7464

Determination ofthe membranetopology of Ost4pand its subunitinteractions in theoligosaccharyltransferase complex in

custompeptide Synthetic OST4 peptide

2003 Herring D

J. Biol. Chem.,Jun 2003; 278:24046 - 24052

ConstitutiveGABAA ReceptorEndocytosis IsDynamin-mediatedand Dependent ona Dileucine AP2Adaptin-binding

custompeptide

Human GABAA receptor cDNAs ,dynamin K44A cDNAs ,Alexa 488-conjugated secondary antibodies ,mouse monoclonal 9E10 anti-mycantibody , mouse polyclonal anti-myc 9E10 ascites fluid

2003 Plotkin B

J. Pharmacol.Exp. Ther., Jun2003; 305: 974 -980

Insulin MimeticAction of SyntheticPhosphorylatedPeptide Inhibitors ofGlycogen Synthase

custompeptide

CK-2 peptide, cAMP-dependentprotein kinase , mitogen-activatedprotein kinase ,

2003 Lum JJ

J. Clin. Invest.,May 2003; 111:1547 - 1554

Vpr R77Q isassociated withlong-termnonprogressive HIVinfection and

custompeptide

Vpr peptides. C-terminal (52-96) Vprwild-type and mutant R77Q peptides

2003 Díaz G

Int. Immunol.,May 2003; 15:565 - 576

Functional analysisof HLA-DPpolymorphism: acrucial role for DPßresidues 9, 11, 35,55, 56, 69 and84–87 in T cell

custompeptide

AAII(12-27) peptide(LQSLVSQFYQTVQDYA)

2003 Qin J

Mol. Cell. Biol.,May 2003; 23:3253 - 3264.

Ste11p, a High-Mobility-Group BoxDNA-BindingProtein, UndergoesPheromone- andNutrient-Regulated

custompeptide

Synthetic P factor , NheI-BamHIDNA

2003 Douglas JL

J. Virol., May2003; 77: 5054 -5064

Inhibition ofRespiratorySyncytial VirusFusion by the SmallMolecule VP-14637

custompeptide

HR2-derived peptide T-118 (33) ,Ribavirin

2003 Hou Y

J. Immunol., Apr2003; 170: 4373 - 4379

Development ofPeptide MimotopesofLipooligosaccharidefrom Nontypeable

custompeptide

anti-LOS Ab, peptide-KLHconjugates

2003 Brehm MA

J. Immunol., Apr2003; 170: 4077 - 4086

Direct Visualizationof Cross-ReactiveEffector andMemory Allo-Specific CD8 TCells Generated in

custompeptide

Synthetic peptides LCMV-NP396-404 (FQPQNGQFI), LCMV-GP33-41 (KAVYNFATC), LCMV-GP276-286 (SGVENPGGYCL), and LCMV-NP205-212 (YTVKYPNL).

2003 Al-Attiyah R

Infect. Immun.,Apr 2003; 71:1953 - 1960.

Synthetic PeptidesIdentifyPromiscuousHuman Th1 CellEpitopes of the

custompeptide Peptides MPB70

2003 Chang N-S

J. Biol. Chem.,Mar 2003; 278:9195 - 9202

JNK1 PhysicallyInteracts with WWDomain-containingOxidoreductase(WOX1) andInhibits WOX1-

custompeptide

synthetic peptide NH2-CKDGWVpYYANHTEEKT-COOH,with tyrosine 33 phosphorylation (pY

2003 Peng C-W

J. Virol., Mar2003; 77: 2843 -2849

Leader Proteinaseof Beet YellowsVirus Functions inLong-Distance

custompeptide

C-terminal oligopeptide of L-Pro(SLFHCDVASAFSSPFYSLPRFIG)

2003 Kemp HA

Mol. Cell. Biol.,Mar 2003; 23:1750 - 1763

Far3 and FiveInteracting ProteinsPrevent PrematureRecovery fromPheromone Arrestin the BuddingYeastSaccharomycescerevisiae

custompeptide

alpha-factor (peptide: H-Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr-OH) Reagents- 3-AT,BSA, ClonNat, CPRG, 5-FOA ,lauryl maltoside (n-docecyl-ß-D-maltoside, ULTROL grade)(Calbiochem); NP-40 (Igepal CA-630)

2003 Tian L

J. Biol. Chem.,Feb 2003; 278:8669 - 8677

Leucine ZipperDomain TargetscAMP-dependentProtein Kinase to

custompeptide LZ1 peptide ,LZ2 peptide

2003 Inoue A

J. Biol. Chem.,Feb 2003; 278:5478 - 5487

Characterization ofthe Motor Activity ofMammalian MyosinVIIA

custompeptide Anti-myosin VIIA Antibodies

2003 Tanaka Y

J. Immunol., Feb2003; 170: 1291 - 1298

Induction ofAntigen-SpecificCTL byRecombinant HIVTrans-ActivatingFusion Protein-Pulsed HumanMonocyte-DerivedDendritic Cells

custompeptide

induced with both viral and tumor Ag-containing TAT FP. Materials andMethods Peptide synthesis Peptideswere purchased from GenemedSynthesis (San Francisco, CA).Syntheses were conducted by astandard solid phase method basedon fluorenylmethoxycarbonyl

2003CavanaughVJ

J. Virol., Feb2003; 77: 1703 -1717

Vigorous Innateand Virus-SpecificCytotoxic T-LymphocyteResponses toMurine

custompeptide

nonapeptide H2N-168YPHFMPTNL176-COOH

2003Bhagwandin VJ

J. Biol. Chem.,Jan 2003; 278:3363 - 3371

Structure andActivity of HumanPancreasin, aNovel TrypticSerine PeptidaseExpressedPrimarily by thePancreas

custompeptide

enzyme-linked immunoadsorbentassay. Peptide synthesis,conjugation, immunizations,bleeding, and titering assays wereconducted by GeneMed Synthesis(South San Francisco, CA). The IgGfraction of rabbit immunoglobulinswas purified from delipidated antis

2003 Ruoppolo M

Protein Sci., Jan2003; 12: 170 -179

Structuralcharacterization oftransglutaminase-catalyzed cross-linking betweenglyceraldehyde 3-phosphatedehydrogenase and

custompeptide

Q17 peptide ,Q43 peptide , ), alpha -cyano-alpha-hydroxycinnamic acid,and 1,1,1,3,3,3-hexafluor-2-propanol (HFIP)

2003 Werner SR

Cancer Letters,Volume 202,Issue 2, 30December 2003,Pages 201-211

Enhanced cell cycleprogression anddown regulation ofp21Cip1/Waf1 byPRL tyrosine

custompeptide human PRL-1, PRL-2

2003DallabridaSM


Adipose tissuegrowth andregression areregulated byangiopoietin-1

custompeptide GAPDH primers

2003 Ceraul SM

InsectBiochemistry andMolecularBiology, Volume33, Issue 11,

An arthropoddefensin expressedby the hemocytesof the Americandog tick,

custompeptide

synthetic defensin peptideconjugated to KLH

2003 Kohm APJ. Autoimm; 21:261-271

Role of ICAM-1 andP-selectinexpression in thedevelopment andeffector function of

custompeptide

Draining LN cells; MOG(35-55)specific T cells;

2003 Ribeiro PD

Peptides,Volume 24,Issue 11,November 2003,Pages 1807-1814

Prevention of lethalmurine candidiasisusing HP (2–20),an antimicrobialpeptide derivedfrom the N-

custompeptide

HP (2–20)A2KKVFKRLEKLFSKIQNDK20,

2003 Jiang L

ChemicalPhysics Letters,Volume 380,Issues 1-2, 13

The binding ofphosphorothioateoligonucleotides toCdS nanoparticles

custompeptide PT-oligoG10, oligoG10

2003 Wu KLH

Neurobiology ofDisease, Volume14, Issue 1,October 2003,Pages 19-31

Expression of pro-inflammatorycytokine andcaspase genespromotes neuronalapoptosis in

custompeptide

2003RosenkildeC

Biochemical andBiophysicalResearchCommunications, Volume 309,Issue 2, 19

Molecular cloning,functionalexpression, andgene silencing oftwo Drosophilareceptors for the

custompeptide

Drosophila pyrokinins-1; drosophilapyrokins-2

2003 Xiao G-Q


PKC isozymeselective regulationof cloned humancardiac delayedslow rectifier K

custompeptide

peptides eV1-7 (HDAPIGYD, ePKCagonist),

2003 Wang Y

Archives ofBiochemistry andBiophysics,Volume 415,

Phospholipidvesicle fusioninduced by saposinC

custompeptide

synthesized human asposin Cpeptide

2003MatarazaJM

Biochemical andBiophysicalResearchCommunications, Volume 305,Issue 2, 30 May

Identification andcharacterization ofthe Cdc42-bindingsite of IQGAP1,

custompeptide

MK24(MVVSFNRGARGQNALRQILAPVVK,which corresponds to residues1054–1077 of IQGAP1)

2003 Adams JC

Journal ofMolecularBiology, Volume328, Issue 2, 25April 2003,Pages 479-494

Characterisation ofDrosophilaThrombospondinDefines an EarlyOrigin ofPentamericThrombospondins

custompeptide

KHL-conjugated synthetic peptideCVFDSTLKGGRLGVF, corresponding to residues1035–1048 of thepredicted D. melanogasterthrombospondin proteinsequence,

2003SlepenkovSV

FEBS Letters,Volume 539,Issues 1-3, 27March 2003,Pages 100-104

Detection of aconcertedconformationalchange in theATPase domain of

custompeptide

p5 (CLLLSAPRR) and Cro(MQERITLKDYAM)peptides

2003 Shore SM

Gene, Volume307, 27 March2003, Pages 175-

Identification of anovel isoform ofCdk9

custompeptide SAPRGRKWPWRRKWRGRGGAC

2003 Liu W

FEMSImmunology andMedicalMicrobiology,Volume 35,Issue 2, 20March 2003,Pages 141-146

N-terminus of M2protein couldinduce antibodieswith inhibitoryactivity againstinfluenza virusreplication

custompeptide

P1: N-KSLLTEVETPIRNEWGCRCNDSSD(aa2-24); P2: KSLLTEVETPIR-G-SLLTEVETPIR (aa 2-12); P3: KETPIRNEWGCR-G-ETPIRNEWGCR (aa 8-18); P4: KNEWGCRCNDSSD-G-NEWGCRCNDSSD(aa 13-24)

2003 DiDonato RJ

The PlantJournal, Volume37, Issue 3: 340-353. doi:10.1046/j.1365-

Arabidopsis ALF4encodes a nuclear-localized proteinrequired for lateralroot formation

custompeptide

2003 Xu W-H

Insect MolecularBiology, Volume12, Issue 5: 509-516. doi:10.1046/j.1365-2583.2003.00437

Molecularcharacterization ofprothoracicotropichormone anddiapause hormonein Heliothis

custompeptide

(Hvi-DH-NH2) andfree C-terminal peptide (Hvi-DH)

2003 Woo S-H

The Journal ofPhysiology,Volume 552,Issue 2: 437-447. doi:

Modulation of Ca2+signalling in ratatrial myocytes:possible role of theα1c carboxyl

custompeptide LA-, K-, LM1-

2003 Diegel MLScandinavian J.Immunol; 58:1-8

MajorHistocompatibilityComplex Class I-RestrictedPresentation of

custompeptide

Immunogenic peptides OVA257-264(SIINFEKL) and OVA323-339(ISQAVHAAHAEINEAGR)

2003 Liu W

FEMSImmunology &MedicalMicrobiology,Volume 35,Issue 2: 141-146. doi:10.1016/S0928-8244(03)00009-9

N-terminus of M2protein couldinduce antibodieswith inhibitoryactivity againstinfluenza virusreplication

custompeptide

P1: N-KSLLTEVETPIRNEWGCRCNDSSD(aa2-24); P2: KSLLTEVETPIR-G-SLLTEVETPIR (aa 2-12); P3: KETPIRNEWGCR-G-ETPIRNEWGCR (aa 8-18); P4: KNEWGCRCNDSSD-G-NEWGCRCNDSSD(aa 13-24)

2003 Sung YK

Cancer Science,Volume 94,Issue 3: 259-262. doi:10.1111/j.1349-

Glypican-3 isoverexpressed inhumanhepatocellularcarcinoma

custompeptide human GPC3

2003 Lovely RS

Journal ofThrombosis andHaemostasis,Volume 1, Issue1: 124-131. doi:

Fibrinogen γ' chainbinds thrombinexosite II

custompeptide YIGSR, YIGSK, CDPGYIGSR

2003 Jaseja M

Journal ofPeptideResearch,Volume 61,Issue 1: 24-39.doi:10.1034/j.1399-

Conformationalstudies ofantimetastaticlaminin-1 derivedpeptides in differentsolvent systems,using solution NMR

custompeptide

2003 Zheng HEu. J. Immunol;33: 1754–1762

Heat shock factor 1-independentactivation ofdendritic cells byheat shock:implication for theuncoupling of heat-

custompeptide

Peptides were synthesized byGenemed Synthesis Inc.(South San Francisco, CA, USA).

2003 Vilar MM

Vaccine, Volume22, Issue 1, 8December 2003,Pages 137-144

An experimentalbivalent peptidevaccine againstschistosomiasis miscl

2003 Qin D


Identification ofpotential bindingsites for the FHAdomain of humanChk2 by in vitro miscl

2003Schumacher MA


Structural Basis ofCore PromoterRecognition in aPrimitive Eukaryote miscl

2003 Lai W-P

Biochimica etBiophysica Acta(BBA) -Molecular Basisof Disease,Volume 1639,

Adaptive responsesof 25-hydroxyvitamin D31-alphahydroxylaseexpression to miscl

2003 Chen W-F

Biochimica etBiophysica Acta(BBA) -Molecular Basisof Disease,

Inhibitory actions ofgenistein in humanbreast cancer(MCF-7) cells miscl

2003 Kulkarni AA


Transmembranesegment 5 of thedipeptidetransporter hPepT1forms a part of the miscl

2003 Li W

Archives of OralBiology, Volume48, Issue 3,March 2003,Pages 177-183

X-linkedamelogenesisimperfecta mayresult fromdecreased miscl

2003 Vidovic D

HumanImmunology,Volume 64,Issue 2,

Specific stimulationof MHC-transgenicmouse T-cellhybridomas with miscl

2003 Zhang N

Invest.Ophthalmol. Vis.Sci., May 2003;44: 3441

MolecularIdentification ofMembranePotential DrivenOrganic Cation miscl

2004 Zhang X

J. Biol. Chem.,Dec 2004; 279:55626 - 55632

Identification of aNovel SerumResponse FactorCofactor in Cardiac

customantipeptideantibodies p49/STRAP antibody

2004 Richard H

J. Bacteriol., Sep2004; 186: 6032 - 6041

Escherichia coliGlutamate- andArginine-Dependent AcidResistanceSystems Increase

customantipeptideantibodies rabbit anti-GadC antibodies

2004SimmondsAC

J. Pharmacol.Exp. Ther., Sep2004; 310: 855 -864

Bioactivation of 1,1-Dichloroethylene byCYP2E1 andCYP2F2 in Murine

customantipeptideantibodies CYP2F1 polyclonal antibody

2004 Fu CT

J. Biol. Chem.,Aug 2004; 279:36943 - 36950

CCN3 (NOV)Interacts withConnexin43 in C6Glioma Cells:POSSIBLEMECHANISM OF

customantipeptideantibodies CCN3 IgG antibody

2004 Gao Y

J. Exp. Biol., Aug2004; 207: 2991 - 3002

Characterizationand expression ofplasma membraneCa2+ ATPase(PMCA3) in thecrayfish

customantipeptideantibodies PMCA3 antibody

2004 Xie J

PNAS, Jul 2004;101: 10750 -10755.

Absence of areductase,NCB5OR, causesinsulin-deficient

customantipeptideantibodies Western blot

2004 Zhu H

J. Biol. Chem.,Jul 2004; 279:30316 - 30325

NCB5OR Is aNovel SolubleNAD(P)HReductase

customantipeptideantibodies NCB5OR,goat anti-rabbit IgG

2004 Henke MO

Am. J. Respir.Cell Mol. Biol.,Jul 2004; 31: 86 - 91

MUC5AC andMUC5B Mucins AreDecreased inCystic Fibrosis

customantipeptideantibodies MUC5AC and MUC5B Antibodies

2004 Shie J-L

J. Biol. Chem.,Jun 2004; 279:25010 - 25016

RTEF-1, a NovelTranscriptionalStimulator ofVascularEndothelial Growth

customantipeptideantibodies anti-RTEF-1 antibody

2004 Veitch GI

J. Cell Sci., Jun2004; 117: 2699 - 2707

Selective assemblyof connexin37 intoheterocellular gapjunctions at theoocyte/granulosa


anti-Cx37 polyclonal antibodies,polyclonal (CT-360),monoclonal(P4G9 E3),

2004 McGee DJ

Eur. J. Biochem.,May 2004; 271:1952 - 1962

Purification andcharacterization ofHelicobacter pyloriarginase, RocF:unique features

customantipeptideantibodies RocF Polyclonal antibodies

2004 Lee G

Genetics, May2004; 167: 311 -323

Hemolymph SugarHomeostasis andStarvation-InducedHyperactivityAffected by GeneticManipulations ofthe Adipokinetic

customantipeptideantibodies anti-AKH antibody

2004VergheseGM

Am. J. Respir.Cell Mol. Biol.,Apr 2004; 30:519 - 529

Mouse ProstasinGene Structure,Promoter Analysis,and RestrictedExpression in Lung

customantipeptideantibodies mProstasin cDNA

2004 Qiao H

PLANT CELL,Mar 2004; 16:582 - 595

The F-Box ProteinAhSLF-S2Physically Interactswith S-RNasesThat May BeInhibited by theUbiquitin/26SProteasome


mouse monoclonal anti-tubulin Ab ,rabbit anti-ubiquitin Ab, alkalinephosphatase-conjugated secondaryantibodies and nitroblue tetrazolumy5-bromo-4-chloro-3-indolylphosphate , AhSLF-S2 protein ,

2004 Miedlich SU

J. Biol. Chem.,Feb 2004; 279:7254 - 7263

Homology Modelingof theTransmembraneDomain of theHuman CalciumSensing Receptor

customantipeptideantibodies polyclonal antibody

2004 Lamont LB

DevelopmentalCell, Volume 7,Issue 5,November 2004,

FBF-1 and FBF-2Regulate the Sizeof the MitoticRegion in the C.

customantipeptideantibodies FBF-2 antibodies

2004 Embers ME

Vaccine, Volume22, Issues 5-6,26 January 2004,Pages 671-681

Differential antibodyresponses to adistinct region ofhumanpapillomavirusminor capsidproteins


A peptide derived from the humanpapillomavirus type 16 (HPV-16)minor capsid protein, L2, haspreviously been reported to inducecross-neutralizing antibodies inmice. In this report, four HPV L2peptides, including the HPV-16peptide and its HPV type 6

2004 McGee DJ

EuropeanJournal ofBiochemistry,Volume 271,Issue 10: 1952-1962. doi:

Purification andcharacterization ofHelicobacter pyloriarginase, RocF:unique featuresamong the

customantipeptideantibodies polyclonal antibodies

2004 Chang M-C

J. Biol. Chem.,Dec 2004; 279:50676 - 50683

The Induction ofProstaglandin E2Production,Interleukin-6Production, CellCycle Arrest, andCytotoxicity inPrimary OralKeratinocytes and

CustomOligo/DNA

Mouse anti-human COX-2monoclonal antibody

2004 Renninger N

Appl. Envir.Microbiol., Dec2004; 70: 7404 -7412

Uranyl Precipitationby Pseudomonasaeruginosa viaControlledPolyphosphateMetabolism

CustomOligo/DNA

......PCR. PCR was performed byusing an Extend High Fidelitysystem (Boehringer Mannheim).Oligonucleotides were purchasedfrom Genemed Synthesis (SouthSan Francisco, Calif.) and QIAGENOperon (Alameda, Calif.).Polyphosphate degradation in crudecell

2004 Sakai T

Endocrinology,Dec 2004; 145:5671 - 5678.

Characterization ofCrustaceanCardioactivePeptide as a NovelInsect MidgutFactor: Isolation,Localization, and

CustomOligo/DNA CCAP cDNA

2004 Nickols HH

J. Biol. Chem.,Nov 2004; 279:46969 - 46980

CalmodulinInteracts with theV2 VasopressinReceptor:ELIMINATION OFBINDING TO THEC TERMINUSALSOELIMINATES

CustomOligo/DNA V2R cDNA

2004Seibenhener ML

Mol. Cell. Biol.,Sep 2004; 24:8055 - 8068

Sequestosome1/p62 Is aPolyubiquitin ChainBinding ProteinInvolved in

CustomOligo/DNA p62 pcDNA3

2004 Etkind PR

Clin. CancerRes., Sep 2004;10: 5656 - 5664

Clonal Isolation ofDifferent Strains ofMouse MammaryTumor Virus-LikeDNA Sequencesfrom Both theBreast Tumors andNon-Hodgkin’sLymphomas of

CustomOligo/DNA

DNA products TOPO TA Cloning kitPCR products-

2004 Ban C

Nucleic AcidsRes., Jul 2004;32: e110

Detection ofprotein–DNAinteraction with aDNA probe:distinction betweensingle-strand and

CustomOligo/DNA dna 5' base [NH2(CH2)6]

2004 Ferree S

Biophys. J., Jul2004; 87: 468 -475

TheHydrodynamics ofDNAElectrophoretic

CustomOligo/DNA

T4 DNA,12 basepair 3'-biotinylatedDNA

2004 Wang Q-L

Hum. Mol.Genet., May2004; 13: 1025 -1040

QRX, a novelhomeobox gene,modulatesphotoreceptor gene

CustomOligo/DNA QRX cDNA

2004 Chen W-F

J. Clin.Endocrinol.Metab., May2004; 89: 2351 -2359

GenisteinEnhances Insulin-Like Growth FactorSignaling Pathwayin Human Breast

CustomOligo/DNA MCF-7 cDNA

2004 Agarwal A

Am. J. Pathol.,May 2004; 164:1683 - 1696

N-Acetyl-CysteinePromotesAngiostatinProduction andVascular Collapsein an Orthotopic

CustomOligo/DNA mRNA.VEGF

2004 Liu A

J. Biol. Chem.,Apr 2004; 279:17449 - 17458

NF- B Site Interactswith Sp Factors andUp-regulates theNR1 Promoterduring NeuronalDifferentiation

CustomOligo/DNA

Antibodies Sp1 (07-124),Sp3(sc13018x and sc644x), Sp4(sc13019x and sc645x), p65 (sc-109x), p50 (sc-114x), p52 (sc-298x),and c-Rel (sc-272x),Recombinantproteins p50 and p49

2004 Koper TE

Appl. Envir.Microbiol., Apr2004; 70: 2342 -

Urease-EncodingGenes in Ammonia-Oxidizing Bacteria

CustomOligo/DNA ureC genes

2004 Chen EBlood, Mar 2004;103: 1710 - 1719

Syndecan-2 isessential forangiogenicsprouting during

CustomOligo/DNA syndecan-2 cDNA

2004 Ahmad S

InternationalJournal ofMedicalMicrobiology,Volume 294,Issue 1, 28 June

PCR-enzymeimmunoassay ofrDNA in thediagnosis ofcandidemia andcomparison with

CustomOligo/DNA

2004 Pager CT

J. Virol., Sep2004; 78: 9154 -9163

SubcellularLocalization andCalcium and pHRequirements forProteolytic

CustomPeptide,ProteinAntibodies SV5 F antipeptide antibodies

2004 Ge L

J. Biol. Chem.,Dec 2004; 279:55419 - 55424

ConstitutiveProtease-activatedReceptor-2-mediated Migrationof MDA MB-231Breast Cancer

custompeptide

Human PAR-2 peptides SLIGKV-NH2 (hAP) and 2f-AP andscrambled PAR-2 peptide (scr-AP)

2004 Bollard CM

J. Exp. Med.,Dec 2004; 200:1623 - 1633

Cytotoxic TLymphocyteTherapy for Epstein-Barr Virus+

custompeptide LMP2 peptide

2004 Fang Q

Eur. Respir. J.,Dec 2004; 24:918 - 924.

Thrombin inducescollagen gelcontraction partiallythrough PAR1

custompeptide

siRNA EGTA,human PAR1 humanPAR4,TGF-ß1,FBS

2004 Li P

J. Biol. Chem.,Nov 2004; 279:50150 - 50156

Perturbation ofLipopolysaccharide(LPS) Micelles bySushi 3 (S3)AntimicrobialPeptide: THEIMPORTANCE OFANINTERMOLECULAR DISULFIDE

custompeptide native S3 peptide

2004 Zheng H

J. Immunol., Nov2004; 173: 5929 - 5933

Cutting Edge:Cross-Presentationof Cell-AssociatedAntigens to MHCClass I Molecule IsRegulated by aMajor Transcription

custompeptide

Mouse embryonic fibroblast (MEF),reagents ADK14NP

2004 Khurana R

Circulation, Oct2004; 110: 2436 - 2443

Angiogenesis-Dependent andIndependentPhases of Intimal

custompeptide PR39 Peptides

2004MitrofanovaE

Clin. CancerRes., Oct 2004;10: 6969 - 6976

Rat Sodium IodideSymporter forRadioiodide

custompeptide rNIS-peptide conjugate

2004 Leen AMBlood, Oct 2004;104: 2432 - 2440

Conserved CTLepitopes on theadenovirus hexonprotein expandsubgroup cross-

custompeptide predict peptides

2004Grassadonia A

Endocrinology,Oct 2004; 145:4728 - 4736

The 90K ProteinIncreases MajorHistocompatibilityComplex Class IExpression and IsRegulated by

custompeptide

17-amino-acid peptide (amino acids530–546),

2004 Turk MJ

J. Exp. Med.,Sep 2004; 200:771 - 782

Concomitant TumorImmunity to aPoorlyImmunogenic

custompeptide gp100/pmel 17 peptide gp10025-33

2004 Frecer V

Antimicrob.AgentsChemother., Sep

De Novo Design ofPotentAntimicrobial

custompeptide V peptide

2004 Santama N

J. Cell Sci., Sep2004; 117: 4537 - 4549

Distribution andfunctions of kinectinisoforms

custompeptide

Polyclonal antibodies V2 (mIn2),V3(mIn3)

2004 Trujillo JD

J. Virol., Sep2004; 78: 9190 -9202

Glycosylation ofImmunodominantLinear Epitopes inthe Carboxy-Terminal Region ofthe CaprineArthritis-Encephalitis VirusSurface Envelope

custompeptide SU 4 peptides

2004 Bai X-FJ. Exp. Med;200: 447 - 458

CD24 ControlsExpansion andPersistence ofAutoreactive TCells in the CentralNervous System

custompeptide MOG peptide 35-55

2004 Eda K

Am J Trop MedHyg, Aug 2004;71: 190 - 195

IDENTIFICATIONOF PEPTIDESTARGETING THESURFACE OFPLASMODIUMFALCIPARUM-INFECTED

custompeptide

DNA preparation kit (QIAprep SpinM13 kit,Synthetic peptides

2004 Yee KO

Am. J. Pathol.,Aug 2004; 165:541 - 552

Expression of theType-1 Repeats ofThrombospondin-1Inhibits TumorGrowth Through

custompeptide

SLLK control peptide or the LSKLpeptide

2004 Anuradha S

J. Biol. Chem.,Jul 2004; 279:28961 - 28969.

Saccharomycescerevisiae Hop1Zinc Finger Motif Isthe Minimal RegionRequired for Its

custompeptide

Hop1-putative ZnF ,C371S mutantpeptide

2004Christodoulou J

J. Biol. Chem.,Jul 2004; 279:29092 - 29100

Evidence forDiffering Roles forEach Lobe of theCalmodulin-likeDomain in a

custompeptide peptide CaM-LD

2004 Xu G

J. Cell Sci., Jul2004; 117: 3207 - 3219

Continuousassociation ofcadherin with ß-catenin requires thenon-receptortyrosine-kinase Fer

custompeptide

antibody NCD-2,Antibodiesconjugated,Anti-pan-cadherin,Polyclonal anti-Fer antibody ,Anti-ß-catenin antibodies ,polyclonal anti-peptide antibody ,Anti-phosphotyrosine (PY20), anti-p120ctn and anti-PTP1B ,Anti-PTP1B ,anti-GSTantibody,Horseradish-peroxida

2004 Reyes AE

Am. J. Pathol.,Jun 2004; 164:2163 - 2174

Acetylcholinesterase-Aß ComplexesAre More Toxicthan Aß Fibrils inRat Hippocampus:Effect on Rat ß-AmyloidAggregation,

custompeptide Ab1-40 peptide

2004 Mason RD

J. Immunol., Jun2004; 172: 7212 - 7219

Antiretroviral DrugResistanceMutations Sustainor Enhance CTLRecognition of

custompeptide test peptides

2004 Connell PP

Cancer Res.,May 2004; 64:3002 - 3005

A Hot Spot forRAD51CInteractionsRevealed by aPeptide That

custompeptide Antibodies polyclonal anti-hsRAD51

2004 Binder RJPNAS, Apr 2004;101: 6128 - 6133

Essential role ofCD91 in re-presentation ofgp96-chaperonedpeptides

custompeptide

NH2-SGLEQLESIINFEKLTEWTS-COOH)vesicular stomatitis virus(VSV)20 (NH2-SLSNLRGYVYQGLKSGNVS-COOH) peptides

2004 Elssner A

J. Immunol., Apr2004; 172: 4987 - 4994

A Novel P2X7Receptor Activator,the HumanCathelicidin-Derived Peptide

custompeptide hexapeptide WKYMVm

2004 Mayrose M

J. Biol. Chem.,Apr 2004; 279:14819 - 14827

LeMPK3 Is aMitogen-activatedProtein Kinase withDual SpecificityInduced duringTomato Defense

custompeptide

peptideMVDANMGAAQFPDFP,LeMPK3Protein

2004 Wu J

Circulation, Apr2004; 109: 1660 - 1667

PR39 InhibitsApoptosis inHypoxic EndothelialCells: Role of

custompeptide PR39 peptide

2004 Cottrell GS

J. Biol. Chem.,Apr 2004; 279:13532 - 13539

Trypsin IV, a NovelAgonist of Protease-activated Receptors2 and 4

custompeptide

peptide PAR2 (SLIGKV-NH2) ,PAR1(TFLLR-NH2) and PAR4 (AYPGKF-NH2),

2004 Zubkov S

PNAS, Mar2004; 101: 3821 - 3826

Structural basis forthe function of aminimembraneprotein subunit of

custompeptide Ost4p peptide

2004 Tse YC

PLANT CELL,Mar 2004; 16:672 - 693

Identification ofMultivesicularBodies asPrevacuolarCompartments in

custompeptide synthetic peptide BP-80 CT

2004 Li Y

J. Immunol., Mar2004; 172: 3225 - 3234.

Cryptic EpitopeIdentified in Ratand HumanCardiac Myosin S2Region Induces

custompeptide

Thirty-two overlapping peptides fromthe S2 region of HCM

2004 Lin P-J

J. Biol. Chem.,Feb 2004; 279:6560 - 6566

Binding of theFactor IX -CarboxyglutamicAcid Domain to theVitamin K-dependent -GlutamylCarboxylase ActiveSite Induces an

custompeptide Peptide FLDDL

2004 Gibson L

J. Immunol., Feb2004; 172: 2256 - 2264

HumanCytomegalovirusProteins pp65 andImmediate EarlyProtein 1 AreCommon Targetsfor CD8+ T Cell

custompeptide

nonamer peptides aa 495–503NLVPMVATV (NV),aa 316–324VLEETSVML (VL),HLA-A*0201-restricted HCMV pp65 and IE1epitopes

2004MamidipudiV

J. Biol. Chem.,Feb 2004; 279:4161 - 4165

Regulation ofInterleukinReceptor-associated Kinase(IRAK)

custompeptide IRAK peptides

2004 Gum ET

Stroke, Feb2004; 35: 590 -595.

Human SerumAlbumin and its N-TerminalTetrapeptide(DAHK) Block

custompeptide N-Terminal Tetrapeptide (DAHK)

2004Goldenberg-Furmanov M

Cancer Res.,Feb 2004; 64:1058 - 1066.

Lyn Is a TargetGene for ProstateCancer: Sequence-Based InhibitionInducesRegression ofHuman Tumor

custompeptide

Anti-Lyn ,anti-Syk ,anti-Fyn,anti-Lck,anti-mitogen-activated proteinkinase (anti-MAPK; C-14),anti-CD19antibodies ,anti-phospho-tyrosinemonoclonal antibody (mAb; clone4G10)

2004 Zurita AJ

Cancer Res.,Jan 2004; 64:435 - 439

CombinatorialScreenings inPatients: TheInterleukin-11Receptor as aCandidate Target in

custompeptide

Soluble CGRRAGGSC-GG-D(KLAKLAK)2, CGRRAGGSC, andD(KLAKLAK)2 peptides, controlpeptide CKGGRAKDC-GG-D(KLAKLAK)2

2004 Niv MY

J. Biol. Chem.,Jan 2004; 279:1242 - 1255

Sequence-basedDesign of KinaseInhibitorsApplicable forTherapeutics andTarget Identification

custompeptide

Fmoc solid phase peptide ,horseradish peroxidase-conjugatedgoat anti-rabbit or donkey anti-mouse secondary Abs

2004 Lee K-W

J. Biol. Chem.,Jan 2004; 279:469 - 476

CellularInternalization ofInsulin-like GrowthFactor BindingProtein-3:DISTINCTENDOCYTIC

custompeptide

peptide(DGIWKASFTTFTVTKYWFYR) andnon-binding peptide(NRDPKHLNDDVVKIDFEDVIAEPEGTHSF)

2004 Singh B

J. Biol. Chem.,Jan 2004; 279:477 - 487

Insulin-like GrowthFactor-independentEffects Mediated bya C-terminal Metal-binding Domain ofInsulin-like Growth

custompeptide

peptides IGFBP-3,anti-MBD5polyclonal antibody

2004 Williams AL

Mol. Biol. Cell,Jan 2004; 15:162 - 175

rsly1 Binding toSyntaxin 5 IsRequired forEndoplasmicReticulum-to-GolgiTransport but DoesNot PromoteSNARE Motif

custompeptide

liquid chromatography-purifiedsynthetic peptides with thesequencesMSCRDRTQEFLSACKSLQSRQNGIQTNK andMSCRDRAQEALSACKSLQSRQNGIQTNK

2004ROBERTSON MP

RNA, Jan 2004;10: 114 - 127

In vitro selection ofribozymesdependent on

custompeptide peptide sRevn,

2004 Jung C-H


Suppression of thefacile latencytransition of α1-antitrypsin variantMmalton by

custompeptide a1AT proteins

2004 Yang Z


A novel hIL-6antagonist peptidefrom computer-aided designcontributes to

custompeptide antagonist peptide PT

2004 Majewski N

Molecular Cell,Volume 16,Issue 5, 3December 2004,Pages 819-830

Hexokinase-MitochondriaInteractionMediated by Akt IsRequired to InhibitApoptosis in the

custompeptide HPLC-purified hexokinase peptide

2004 Liu W


High epitopedensity in a singlerecombinantprotein molecule ofthe extracellulardomain of influenzaA virus M2 protein

custompeptide

peptide of the M2e epitope,N-KSLLTEVETPIRNEWGCRCNDSSD(aa2–24),

2004McGargillMA

Immunity; 21:781-791

A Deficiency inDrak2 Results in aT CellHypersensitivityand an Unexpected

custompeptide

MOG35-55 (MEVGWYRSPFSRvested and stained with Annexin V(Pharmingen, San Diego, CA).VVHLYRNGK

2004 Wei Z-J

Journal of InsectPhysiology,Volume 50,Issue 12,December 2004,Pages 1151-1161

Molecular cloning,developmentalexpression, andtissue distribution ofthe gene encodingDH, PBAN andother FXPRL

custompeptide H.armigera PBANamide

2004 Vidovic D

Immunobiology,Volume 209,Issue 7, 9November 2004,

Tumorimmunotherapywith alternativereading frame

custompeptide

2004 Thorne ME


Heat-inducedoligomerization ofgp96 occurs via asite distinct fromsubstrate binding

custompeptide

VSV8 (RGYVYQGL) and VSV19(SLSDLRGYVYQGLKSGNVS)

2004 Mohindru M

J.Neuroimmunol;155: 127-135

Functionalmaturation ofproteolipidprotein139–151-specific Th1 cells inthe central nervous

custompeptide PLP139–151 (HSLGKWLGHPDKF)

2004 Qin W


A novel TNFαantagonizingpeptide-Fc fusionprotein designedbased on CDRs ofTNFα neutralizing

custompeptide

peptide (YINTGYDGLYYNSMD)

2004 Ogata Y

AnalyticalBiochemistry,Volume 331,Issue 1, 1August 2004,Pages 161-168

Automated affinitychromatographymeasurements ofcompound mixturesusing a lab-on-valve apparatuscoupled to

custompeptide

peptideDWAQEYA

2004 Liu W

ImmunologyLetters, Volume93, Issues 2-3,15 May 2004,Pages 131-136

MonoclonalantibodiesrecognizingEVETPIRN epitopeof influenza A virusM2 protein couldprotect mice fromlethal influenza Avirus challenge

custompeptide

NM2: K-SLLTEVETPIR-G-SLLTEVETPIR(contains aa2–12 sequence of M2e,SLLTEVETPIR);MM2: K-ETPIRNEWGCR-G-ETPIRNEWGCR (containsaa8–18 sequence of M2e,ETPIRNEWGCR); CM2:K-NEWGCRCNDSSD-G-NEWGCRCNDSSD (containsaa8–18 sequence of M2e,NEWGCRCNDSSD).

2004Chesnokova LS

FEBS Letters,Volume 565,Issues 1-3, 7May 2004,Pages 65-69

The insectantimicrobialpeptide, -pyrrhocoricin, bindsto and stimulates

custompeptide p5, L-PYR, D-PYR

2004 Slovut DP

CardiovascularResearch,Volume 62,Issue 2, 1 May

Increased vascularsensitivity andconnexin43expression after

custompeptide

synthetic peptide corresponding toamino

2004 Qi X


Fusogenic domainand lysines insaposin C

custompeptide human saposin C peptides

2004Kaidanovich-Beilin O

BiologicalPsychiatry,Volume 55,Issue 8, 15 April2004, Pages 781-

Rapidantidepressive-likeactivity of specificglycogen synthasekinase-3 inhibitor

custompeptide L803-mts, cpL803-mts

2004 Zhao J-Y

RegulatoryPeptides,Volume 118,Issues 1-2, 15April 2004,Pages 25-31

Functional analysisof the SGNP I inthe pupal diapauseof the orientaltobacco budworm,Helicoverpa assulta

custompeptide Has-SGNP I, free acid C-terminus

2004 Bauerly KA

The Journal ofNutritionalBiochemistry,Volume 15,Issue 3, March

Functional andmolecularresponses ofsuckling rat pupsand human

custompeptide Ctr1, Atp7A

2004 Tsai C-Y

InternationalImmunopharmacology, Volume 4,Issue 1, January2004, Pages 47-

Proinflammatorycytokines enhanceCOX-1 geneexpression incultured rat

custompeptide COX-1, COX-2

2004 Zhang T-Y

Journal of InsectPhysiology,Volume 50,Issue 1, January2004, Pages 25-33

Cloning andexpression of thecDNA encoding theFXPRL family ofpeptides and afunctional analysisof their effect on

custompeptide

amidated DH-like, PBAN, aSGNP,bSGNP, gSGNP, free C-terminalDH-like

2004 CHEN J

Clinical &ExperimentalImmunology,Volume 138,Issue 2: 245-

Allogenic donorsplenocytespretreated withantisense peptideagainst B7 prolong

custompeptide

The peptide was synthesized on asolid phase peptide synthesizer(Multiple Peptide Synthesizer;Genemed Synthesis

2004 Martin ME

MolecularMicrobiology,Volume 54,Issue 1: 60-74.doi:10.1111/j.1365-2958.2004.04251

Cell cycle-dependentabundance, stabilityand localization ofFtsA and FtsQ inCaulobactercrescentus

custompeptide

The peptides were purified togreater than 70% purity, coupled toKeyhole Limpet Hemocyanin andcoinjected in equimolar ratio intorabbits by Genemed Synthesis, Inc

2004 Brennan D

Differentiation,Volume 72,Issue 8: 434-449. doi:10.1111/j.1432-

Differentialstructuralproperties andexpression patternssuggest functional

custompeptide

‘‘N’’-FQGDPDETLETPLYG-‘‘C’’ andN’-TSTEKPVTLSITPNV-‘‘C’’

2004 Munks MW

Immunology,Volume 112,Issue 4: 559-566. doi:10.1111/j.1365-2567.2004.01917.x

4-1BB and OX40stimulationenhance CD8 andCD4 T-cellresponses to aDNA prime,poxvirus boostvaccine

custompeptide

For analysis of peptide-specific CD8T cells, spleen cells were culturedfor 5–6 hr in the presence ofbrefeldin A (GolgiPlug, BDPharmingen, San Diego, CA) with orwithout 1 µg/ml synthetic peptide(Genemed Synthesis

2004 Soltau M

Journal ofNeurochemistry,Volume 90,Issue 3: 659-665. doi:10.1111/j.1471-4159.2004.02523.x

Insulin receptorsubstrate of 53 kDalinks postsynapticshank to PSD-95

custompeptide

C-termini of GKAP/SAPAP (sequence IYIPEAQTRL),the rat somatostatin receptorsubtype 3 (KASTLSHL), the NMDAreceptor 2 A subunit(KKLSSIESDV) and IRSp53(SGSGTLVSTV)

2004 Cowley S

MolecularMicrobiology,Volume 52,Issue 6: 1691-1702. doi:10.1111/j.1365-2958.2004.04085.x

The Mycobacteriumtuberculosis proteinserine/threoninekinase PknG islinked to cellularglutamate/glutamine levels and isimportant forgrowth in vivo

custompeptide

Protein samples in gel slices weresent to Genemed Synthesis wherePknG was electroeluted from gelslices and injected into rabbits.Polyclonal rabbit anti-PknGantibodies were semi-purified usingpreblotting against a blot of PknGmutant protein extract

2004 Suen JL

ARTHRITIS &RHEUMATISM;50: 3250–3259

Treatment ofMurine Lupus UsingNucleosomal T CellEpitopes IdentifiedbyBoneMarrow–DerivedDendritic Cells

custompeptide

These series of peptidesand ovalbumin 323–339(OVA323–339) were synthesizedand purified by high-performanceliquid chromatography(GeneMed, South San Francisco,CA).

2004GERTONGL

Ann. N.Y. Acad.Sci., Jun 2004;1022: 306 - 316

A SerumProteomicsApproach to theDiagnosis of miscl ELISA kits,SELDI

2004Sambandam T


Increasedpeptidylargininedeiminase type II inhypoxic astrocytes miscl

2004

Vianna deCarvalhoUhl M

Vaccine, Volume22, Issues 31-32,22 October2004, Pages4191-4202

Suitability of arecombinantStaphylococcusaureus enterotoxinC bovine variant forimmunodiagnostics miscl

2004 Arap MA

Cancer Cell,Volume 6, Issue3, September2004, Pages 275-284

Cell surfaceexpression of thestress responsechaperone GRP78enables tumor miscl

2004 Kopan S

Biochemical andBiophysicalResearchCommunications, Volume 319,Issue 1, 18 June2004, Pages 58-

The lysosomaldegradation ofneuromedin B isdependent ontripeptidylpeptidase-I:evidence for the miscl

2004 Miller CL

Neurobiology ofDisease, Volume15, Issue 3, April2004, Pages 618-629

Expression of thekynurenine pathwayenzyme tryptophan2,3-dioxygenase isincreased in thefrontal cortex of miscl

2004 Han Z

Peptides,Volume 25,Issue 4, April2004, Pages 551-561

Identification andcharacterization ofpeptides that bindto cyanovirin-N, apotent humanimmunodeficiency miscl

2004 Shepard JL

Methods in CellBiology, Volume76, 2004, Pages

Analysis of the CellCycle in ZebrafishEmbryos miscl

2004 Agarwal AAm. J. Path; 164:1683-1696

N-Acetyl-CysteinePromotesAngiostatinProduction andVascular Collapsein an OrthotopicModel of BreastCancer miscl

Real-time PCR primers targetingmurine PECAM-1, murine VEGF,murine cyclophilin, humanVEGF, and human cyclophilin weredesigned usingPrimer Express software (AppliedBioSystems, FosterCity, CA) and synthesized byGenemed Synthesis, SouthSan Francisco,

2005 Wang I-C

Mol. Cell. Biol.,Dec 2005; 25:10875 - 10894

Forkhead Box M1Regulates theTranscriptionalNetwork of GenesEssential for MitoticProgression and

customantipeptideantibodies anti-FoxM1 antibody

2005 Lei MG

Infect. Immun.,Dec 2005; 73:8136 - 8143

Regulation ofCellular Caveolin-1Protein Expressionin MurineMacrophages by

customantipeptideantibodies TLR4 Antibodies

2005 Habibian R

J. Biol. Chem.,Nov 2005; 280:39637 - 39643

Functional Analysisof Conserved PolarResidues in Vc-NhaD, Na+/H+Antiporter of Vibrio

customantipeptideantibodies Vc-NhaD peptide

2005 Chin YR

J. Virol., Nov2005; 79: 13606 - 13617

Mechanism forRemoval of TumorNecrosis FactorReceptor 1 fromthe Cell Surface by

customantipeptideantibodies RIDß antibody

2005MeulendykeKA

J. Virol., Oct2005; 79: 12643 - 12649

Endocytosis Playsa Critical Role inProteolyticProcessing of the

customantipeptideantibodies Peptides anti-Stk33

2005 Li C

J. Exp. Med., Oct2005; 202: 975 -986

Lysophosphatidicacid inhibits choleratoxin-inducedsecretory diarrheathrough CFTR-


R1104 monoclonal mouse antibody, NBD-R polyclonal rabbitantibodyAnti-LPA2 antibody (rabbit-2143), Anti-Flag mAb

2005 Hou F

Mol. Biol. Cell,Aug 2005; 16:3908 - 3918

Two HumanOrthologues ofEco1/Ctf7AcetyltransferasesAre Both Required

customantipeptideantibodies EFO1 and EFO2 peptides

2005ThompsonBE

Development,Aug 2005; 132:3471 - 3481

Dose-dependentcontrol ofproliferation andsperm specification

customantipeptideantibodies FOG-1 antibodies

2005MohamedHA

J. Biol. Chem.,Jul 2005; 280:27035 - 27043

cAMP-responseElements in Aplysiacreb1, creb2, andAp-uch Promoters:IMPLICATIONSFOR FEEDBACKLOOPS

customantipeptideantibodies CREB1-Rabbit polyclonal antibodies

2005 Onorato TM

J. Biol. Chem.,May 2005; 280:19527 - 19534

Phosphorylation ofRat LiverMitochondrialGlycerol-3-phosphate

customantipeptideantibodies antibody IM1GAT

2005 Liu H-Y

J. Biol. Chem.,May 2005; 280:19461 - 19471

Human TumorousImaginal Disc 1(TID1) Associateswith Trk ReceptorTyrosine Kinasesand Regulates

customantipeptideantibodies anti-TID1N antibody

2005 Lee K-W

J. Biol. Chem.,Apr 2005; 280:16942 - 16948

Rapid ApoptosisInduction by IGFBP-3 Involves anInsulin-like GrowthFactor-independentNucleomitochondrial

customantipeptideantibodies polyclonal rabbit anti-Nur77 antibody

2005 Saeki N

J. Biol. Chem.,Mar 2005; 280:10128 - 10134

BIG1 Is a BindingPartner of MyosinIXb and RegulatesIts Rho-GTPaseActivating ProteinActivity


anti-myosin IXb and anti-BIG1antibodies, Vectors pBTM-116 andpGAD-424 and yeast strain L40,Anti-FLAG M2 affinity gel , BIG1cDNA

2005 Kim TS

J. Biol. Chem.,Mar 2005; 280:8694 - 8704

Delayed DarkAdaptation in 11-cis-RetinolDehydrogenase-deficient Mice: A


mouse rdh11 cDNA , anti-RDH11polyclonal antibody , goat anti-rabbitIgG conjugated to horseradishperoxidase

2005 Golabek AA

J. Biol. Chem.,Mar 2005; 280:7550 - 7561

Glycosaminoglycans ModulateActivation, Activity,and Stability ofTripeptidyl-


peptide MOCAc-Gly-Lys-Pro-Ile-Pro-Phe-Arg-Leu-Lys-(Dnp)-r-NH2

2005 Koga Y

J. Biol. Chem.,Feb 2005; 280:4983 - 4991

p116Rip DecreasesMyosin IIPhosphorylation byActivating MyosinLight Chain


Mouse anti-MLC20 IgM monoclonalantibody,Rabbit anti-MYPT1polyclonal antibody

2005 Xu KYFASEB J, Jan2005; 19: 53 - 61.

Evidence that theH1-H2 domain of 1subunit of(Na++K+)-ATPaseparticipates in the


anti-NKA 3 (MA3-915) antibodies,anti-NKA 2 antibody

2005 Zhang G

TsinghuaScience &Technology,Volume 10,Issue 4, August

MonoclonalAntibodiesRecognizing HIV-1gp41 Could InhibitEnv-Mediated


2005 Zou P

InternationalImmunopharmacology, Volume 5,Issue 4, April2005, Pages 631-635

The epitoperecognized by amonoclonalantibody ininfluenza A virusM2 protein is

customantipeptideantibodies M2e; residues of M2e

2005 Dieker JW

Journal ofImmunologicalMethods,Volume 296,Issues 1-2,January 2005,

Mimotopes forlupus-derived anti-DNA andnucleosome-specificautoantibodies


2005 Jeon SJ. Neurochem.95, 1608-1616

Microtubule affinity-regulating kinase 1(MARK1) isactivated byelectroconvulsiveshock in the rathippocampus


MARK polyclonal antibodies wereproduced in rabbits against aMARK C-terminal peptide(KNIASKIANELKL) (GenemedSynthesis, South San Francisco,CA, USA), which corresponded totherat MARK sequence from aminoacids 781–793 (referred to asa-MARK) and the N

2005 Ribeiro FM

Journal ofNeurochemistry,Volume 94,Issue 1: 86-96.doi:

Constitutive high-affinity cholinetransporterendocytosis isdetermined by a

customantipeptideantibodies polyclonal rabbit antibody anti-CHT1

2005 Sebollela A

J. Biol. Chem.,Sep 2005; 280:31949 - 31956

Heparin-bindingSites inGranulocyte-MacrophageColony-stimulatingFactor:LOCALIZATION

CustomDNA mGM-CSF cDNA

2005 Castro M

PNAS, Nov2005; 102:16084 - 16089

Turn-on switch inparathyroidhormone receptorby a two-stepparathyroidhormone bindingmechanism

CustomOligo/DNA

pcDNA3, , Peptides. HumanPTH(1-34), radioligand [125I]-[Nle-8,21, Tyr-34]-human PTH(1-34)-OH(2,200 Ci/mmol), Human [Lys-13(N-5-carboxy-TMR)]PTH(1-34)NH2[herein termed PTH(1-34)TMR]

2005 Mujica AO

FEBS J., Oct2005; 272: 4884 - 4898.

Differentialexpression patternof the novelserine/threonine

CustomOligo/DNA STK33/Stk33-DNA ,Stk33-peptide ,

2005 Wada Y

FASEB J, Sep2005;doi:10.1096/fj.05-4037fje

Preconditioning ofprimary humanendothelial cellswith inflammatorymediators alters the"set point" of the cell

CustomOligo/DNA

Primers were designed using thePrimer Express oligo designsoftware (Applied BioSystems,Foster City, CA) and synthesized byGenemed Synthesis (South SanFrancisco, CA). All primer sets weresubjected to rigorous databasesearches to identify potential c

2005ChigurupatiS

Cancer Res.,Sep 2005; 65:8519 - 8529.

CalcitoninStimulates MultipleStages ofAngiogenesis byDirectly Acting on

CustomOligo/DNA CT-pcDNA3.1,calcitonin cDNA

2005 Xie F

Evid. BasedComplement.Altern. Med., Sep2005; 2: 353 -361

The osteoprotectiveeffect of Herbaepimedii (HEP)extract in vivo andin vitro

CustomOligo/DNA

......One microliter of total cDNAwas amplified in each PCR reactionmixture containing 0.5 muM ofsense and antisense primers(Genemed Synthesis, Inc., SouthSan Francisco, CA, USA) ofselected genes (Table 1). The PCRreaction mixture (in a total volu

2005 Li FCH

Mol. Pharmacol.,Jul 2005; 68: 179- 192.

In the RostralVentrolateralMedulla, the 70-kDa Heat ShockProtein (HSP70),but Not HSP90,ConfersNeuroprotectionagainst FatalEndotoxemia via

CustomOligo/DNA

horseradish peroxidase-conjugatedsheep anti-mouse IgG , anti-rabbitIgG normal mouse serum, mousemonoclonal antiserum

2005 Qu Y

Circulation, Jun2005; 111: 3034 - 3041

Novel MolecularMechanismInvolving 1D(Cav1.3) L-TypeCalcium Channel in

CustomOligo/DNA

Anti-Ro/La antibodies , anti-alpha1D antibody, human alpha 1D, ratß2a, and alpha 2 delta cDNAs

2005 Mao T

Plant Physiology,Jun 2005; 138:654 - 662

Two Microtubule-Associated Proteinsof the ArabidopsisMAP65 FamilyFunction Differently

CustomOligo/DNA AtMAP65-6 cDNA

2005 Qu Y

Am J PhysiolHeart CircPhysiol, May2005; 288:

Localization andmodulation of 1D(Cav1.3) L-type Cachannel by protein

CustomOligo/DNA PCR cDNA

2005 Lin MY

J. Immunol., May2005; 174: 5583 - 5592

A Pivotal Role forthe MultifunctionalCalcium/Calmodulin-Dependent ProteinKinase II in T Cells:From Activation to

CustomOligo/DNA pcr cdna

2005 Yuan R

Molecular andCellularEndocrinology,Volume 229,Issues 1-2, 14

Targetedoverexpression ofcalcitonin ingonadotrophs oftransgenic mice

CustomOligo/DNA PCR primers

2005 Hu J

J. Biol. Chem.,May 2005; 280:18943 - 18949.

StructuralCharacterization ofa Novel CblPhosphotyrosineRecognition Motif in

custompeptide APS pTyr-618 Phosphopeptides

2005 Thelin WR

J. Biol. Chem.,Dec 2005; 280:41512 - 41520

The Cystic FibrosisTransmembraneConductanceRegulator IsRegulated by aDirect Interaction

custompeptide CFTR peptides

2005 Niland BJ. Immunol; 175:8365 - 8378

CD8+ T Cell-Mediated HLA-A*0201-RestrictedCytotoxicity toTransaldolasePeptide 168–176 inPatients withMultiple Sclerosis

custompeptide

myelin oligodendrocyte protein(MOG), did not differconsiderably...transferred MBP-specific (38) or MOG-specific CD8 Tcells induce...99% homogeneity byGenemed (Genemed Synthesis).

2005Sanchez-Merino V

J. Immunol., Nov2005; 175: 6976 - 6986

HIV-1-SpecificCD8+ T CellResponses andViral Evolution in

custompeptide

anti-IFN- gamma mAb QIAampDNA minikit , Biotest ABC SSPtray

2005GoldbergSM

Clin. CancerRes., Nov 2005;11: 8114 - 8121

Comparison of TwoCancer VaccinesTargetingTyrosinase:Plasmid DNA and

custompeptide

Human tyrosinase cDNA ,Mousetyrosinase peptides , Anti-pep7rabbit polyclonal anti-mousetyrosinase antibody

2005Navaratnam D

Biophys. J., Nov2005; 89: 3345 -3352

N-Terminal-MediatedHomomultimerization of Prestin, the

custompeptide

Affinity-purified rabbit polyclonalantibodies

2005 Lee L-F

PNAS, Nov2005; 102:15995 - 16000

The role of TNF- inthe pathogenesis oftype 1 diabetes inthe nonobesediabetic mouse:Analysis of

custompeptide Peptides D2O and SDS-D25

2005 Ellis NMJ

J. Immunol., Oct2005; 175: 5448 - 5456

T Cell Mimicry andEpitope Specificityof Cross-ReactiveT Cell Clones fromRheumatic Heart

custompeptide

Synthetic peptides, AntigensStreptococcal recombinant M6protein (rM6) ,

2005

Ferrao-GonzalesAD

J. Biol. Chem.,Oct 2005; 280:34747 - 34754

Controlling -AmyloidOligomerization bythe Use ofNaphthaleneSulfonates:

custompeptide

peptide Synthetic A beta-1-42 ,Abeta-13-23

2005StraathofKC

J. Immunol., Sep2005; 175: 4137 - 4147

Characterization ofLatent MembraneProtein 2 Specificityin CTL Lines fromPatients with EBV-Positive

custompeptide LMP2 peptides,

2005 Tim Tian MBlood, Sep 2005;106: 2105 - 2112

Bcl10 can promotesurvival of antigen-stimulated Blymphocytes

custompeptide

Bcl10 cDNAs , NF-alpha B-inhibitingpeptide(DRQIKIWFQNRRMKWKKTALDWSWLQTE)goat anti-mouseimmunoglobulin M (IgM; µ-chain-specific), c-Jun N-terminal kinases(JNKs), p38 mitogen-activatedprotein (MAP) kinase, and p44/42extracellular signal-regulated ki

2005AuchtungJM

PNAS, Aug2005; 102:12554 - 12559

Regulation of aBacillus subtilismobile geneticelement byintercellular

custompeptide PhrI pentapeptide

2005 Phillipson A

Am J PhysiolHeart CircPhysiol, Aug2005; 289: H898

Protein kinase C-inhibition exertscardioprotectiveeffects in ischemia-

custompeptide PKC-z peptide

2005 Feng Y-H

Hypertension,Aug 2005; 46:419 - 425

UnconventionalHomologousInternalization ofthe Angiotensin IIType-1 Receptor

custompeptide Sar1Ang II peptide

2005 Feng Y-H

Mol. Pharmacol.,Aug 2005; 68:347 - 355

Single Mutations atAsn295 andLeu305 in theCytoplasmic Half ofTransmembrane -Helix Domain 7 ofthe AT1 ReceptorInduce

custompeptide Ang II peptide

2005 Omiyi D

J. Pharmacol.Exp. Ther., Aug2005; 314: 542 -551

Protein Kinase C IIPeptide InhibitorExertsCardioprotectiveEffects in Rat

custompeptide PKC betaII peptide

2005ChakravartiR

Mol. Biol. Cell,Aug 2005; 16:3678 - 3691

Functional Role ofSyndecan-1Cytoplasmic VRegion inLamellipodial

custompeptide TAT peptides

2005 Yang LBlood, Jul 2005;106: 584 - 592

ICAM-1 regulatesneutrophil adhesionand transcellularmigration of TNF- -activated vascular

custompeptide ICAM-1 Peptides

2005NussbaumAK

J. Immunol., Jul2005; 175: 1153 - 1160

Immunoproteasome-Deficient MiceMount LargelyNormal CD8+ TCell Responses toLymphocytic

custompeptide LCMV NP205 peptide

2005 Smith CEPNAS; 102: 9595- 9600

Differentialinduction of IgE-mediatedanaphylaxis aftersoluble vs. cell-bound tolerogenic

custompeptide

MOG)35-55,MOG92-106,OVA323-339

2005WeaverJGR

J. Clin. Invest.,Jul 2005; 115:1828 - 1838

Inhibition ofadenine nucleotidetranslocator porefunction andprotection against

custompeptide Vpr-derived peptide

2005 Xiao R

J. Biol. Chem.,Jun 2005; 280:21099 - 21106

Catalysis ofThiol/DisulfideExchange:GLUTAREDOXIN 1AND PROTEIN-DISULFIDEISOMERASE USEDIFFERENT

custompeptide

GSSG, NADPH, cCMP, andglutathione reductase , peptideNRCSQGSCWN, with the N- and C-terminal groups

2005 Sainz B

J. Virol., Jun2005; 79: 7195 -7206

Identification andCharacterization ofthe Putative FusionPeptide of theSevere AcuteRespiratory

custompeptide SARS-CoV Peptides

2005 Douglas JL

Antimicrob.AgentsChemother., Jun2005; 49: 2460 -2466

Small MoleculesVP-14637 and JNJ-2408068 InhibitRespiratorySyncytial Virus

custompeptide peptide T-118

2005 Solovjeva L

Mol. Biol. Cell,May 2005; 16:2518 - 2528

High Mobility ofFlap Endonuclease1 and DNAPolymeraseAssociated withReplication Foci in

custompeptide

peptide N-CLTFGS(PO4)PVLMRHLTA-C

2005 Mason RD

J. Virol., May2005; 79: 5529 -5536

Cross-ReactiveCytotoxic TLymphocytesagainst HumanImmunodeficiencyVirus Type 1

custompeptide Peptide-specific CTL

2005 Jaimes MC

J. Virol., Apr2005; 79: 4568 -4579

Characterization ofHomologous andHeterologousRotavirus-SpecificT-Cell Responses

custompeptide 10-mers Peptide

2005 Pascual R

J. Virol., Apr2005; 79: 5142 -5152

A PeptidePertaining to theLoop Segment ofHumanImmunodeficiencyVirus gp41 Bindsand Interacts with

custompeptide HIVHXB2R Peptides

2005 Han G

J. Immunol., Apr2005; 174: 4516 - 4524

Active ToleranceInduction andPrevention ofAutoimmuneDiabetes byImmunogeneTherapy UsingRecombinantAdenoassociatedVirus ExpressingGlutamic Acid

custompeptide Ag GAD peptides

2005 Wang G

Protein Sci., Apr2005; 14: 1082 -1090

NMRcharacterization ofthe Escherichia colinitrogen regulatoryprotein IIANtr insolution andinteraction with itspartner protein, NPr

custompeptide

......are as follows: the syntheticpeptide with a sequencecorresponding to the first 15residues of enzyme IIAGlc ( 95%pure from Genemed Synthesis,Inc.), 1 mM in water at pH 5.4; HPr,1 mM at pH 7.1; NPr, 1 mM at pH~7; IIANtr, 1 mM at pH 7.3; the N-

2005 Daniel D

Cancer Res.,Mar 2005; 65:2018 - 2025

CD4+ T Cell-Mediated Antigen-SpecificImmunotherapy in a

custompeptide

peptides E7 p44-63, E7 p18-38 (23),and Tag p362-384

2005StraathofKCM

Blood, Mar 2005;105: 1898 - 1904

Treatment ofnasopharyngealcarcinoma withEpstein-Barrvirus–specific Tlymphocytes

custompeptide

Peptides LMP1, HLA-A2:YLQQNWWTL, YLLEMLWRL,LMP2, HLA-A2, HLA-A2–restricted cytomegaloviruspp65–derived peptide NLVPMVATV

2005 Staska LM

Infect. Immun.,Mar 2005; 73:1321 - 1329

Identification ofVaccine CandidatePeptides in theNcSRS2 SurfaceProtein ofNeospora caninumby Using CD4+Cytotoxic TLymphocytes and

custompeptide NcSRS2 peptides

2005 Shiau C-W

Cancer Res.,Feb 2005; 65:1561 - 1569

ThiazolidenedionesMediate Apoptosisin Prostate CancerCells in Partthrough Inhibition ofBcl-xL/Bcl-2

custompeptide Bcl-xL Peptides

2005 Aklujkar M

J. Bacteriol., Feb2005; 187: 1334 - 1343

The PuhB Proteinof RhodobactercapsulatusFunctions inPhotosyntheticReaction CenterAssembly with a

custompeptide

PeptidesSMFDKPFDYENGSKFC(NH2)-(KLH) and (KLH)-LPERAHQAPSPYTTEV-(COO) (34

2005 Misra UM

J. Immunol., Feb2005; 174: 2092 - 2097

The Role of MTJ-1in Cell SurfaceTranslocation ofGRP78, a Receptorfor 2-

custompeptide Polyclonal Abs , Anti-actin Abs,

2005 Liberman Z

J. Biol. Chem.,Feb 2005; 280:4422 - 4428

Serine 332Phosphorylation ofInsulin ReceptorSubstrate-1 byGlycogen Synthase

custompeptide IRS-1 Peptide

2005 Xie X-Q

J. Biol. Chem.,Feb 2005; 280:3605 - 3612.

NMR StructuralComparison of theCytoplasmicJuxtamembraneDomains of G-protein-coupledCB1 and CB2

custompeptide

peptides, CB1I397-G418 ,CB2I298-K319

2005 Leong W-I

Am. J. ClinicalNutrition, Feb2005; 81: 445 -453

Iron transporters inrat mammarygland: effects ofdifferent stages of

custompeptide DMT1 and FPN1 antibodies

2005 Weller GER

Cancer Res.,Jan 2005; 65:533 - 539

Ultrasonic Imagingof TumorAngiogenesis UsingContrastMicrobubblesTargeted via the

custompeptide RRL Peptide

2005 Quitsch A

J. Neurosci., Jan2005; 25: 479 -487

Postsynaptic ShankAntagonizesDendrite BranchingInduced by theLeucine-RichRepeat ProteinDensin-180

custompeptide

......synapse-associated protein-associated protein (SAPAP)(sequence IYIPEAQTRL) and delta-catenin (HYPASPDSWV) wereobtained from Genemed Synthesis(San Francisco, CA). The peptideswere coupled to N-hydroxyl-succinimidyl (NHS)-activatedSepharose (Ame

2005 Rotllant J

Endocrinology,Jan 2005; 146:71 - 76

Stimulation ofCortisol Release bythe N Terminus ofTeleost ParathyroidHormone-RelatedProtein in InterrenalCells in Vitro

custompeptide

Piscine (1–34)PTHrP, (2–34)PTHrP,(3–34)PTHrP, (7–34)PTHrP,(10–20)PTHrP, (79–93)PTHrP, and(100–125)PTHrP , Human(1–39)ACTH, corticotropin-inhibitingpeptide (CIP),

2005 Yoon H-G

Mol. Cell. Biol.,Jan 2005; 25:324 - 335.

Reading andFunction of aHistone CodeInvolved inTargeting

custompeptide GST-TBL1 Peptides

2005 Palomba ML

Clin. CancerRes., Jan 2005;11: 370 - 379

CD8+ T-Cell–DependentImmunity FollowingXenogeneic DNAImmunizationagainst CD20 in a

custompeptide CD20 cDNA

2005 Liu A

Archives ofBiochemistry andBiophysics,Volume 443,Issues 1-2, 15

Role of lysineresidues inmembraneanchoring ofsaposin C

custompeptide saposin peptide

2005 Zhang G

Immunobiology,Volume 210,Issue 9, 15November 2005,

Neutralization ofHIV-1 primaryisolate by ELDKWA-specific murine

custompeptide ELDKWA-epitope-peptide P1; CP

2005 Andrali SS


Ataxin-10 interactswith O-GlcNActransferase OGT inpancreatic β cells

custompeptide OGT; Ataxin-10

2005 Dong X-N

ImmunologyLetters, Volume101, Issue 1, 15October 2005,

The neutralizingepitope ELDKWAon HIV-1 gp41:Genetic variability

custompeptide

2005 Yu L

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1716,Issue 1, 1October 2005,Pages 29-39

Investigation of anovel artificialantimicrobialpeptide byfluorescencecorrelationspectroscopy: Anamphipathiccationic pattern is

custompeptide V4-TMR

2005 Raikwar HPJ. Neuroimmuno;167: 99-107

PPARγ antagonistsexacerbate neuralantigen-specificTh1 response andexperimental

custompeptide MOGp35-55

2005 Roggero CM

DevelopmentalBiology, Volume285, Issue 2, 15September 2005,Pages 422-435

Protein kinase C-mediatedphosphorylation ofthe two polybasicregions ofsynaptotagmin VI

custompeptide RRLKKKKTTIKKNTL

2005 Hsu P-H

Geochimica etCosmochimicaActa, Volume 69,Issue 18, 15September 2005,Pages 4521-4533

New evidence forcovalent coupling ofpeptides to humicacids based on 2DNMR spectroscopy:A means for

custompeptide

N-labeled peptide with the sequenceGGGR and with the threeglycines N-labeled

2005 Subklewe M

HumanImmunology,Volume 66,Issue 9,September 2005,Pages 938-949

Dendritic CellsExpand EpsteinBarr Virus SpecificCD8+ T CellResponses MoreEfficiently ThanEBV Transformed

custompeptide

synthetic peptides FLRGRAYGL(HLA-B8/EBNA3A325-333), CLGGLLTMV(HLA-A2/LMP2a426-434) and RPPIFIRRL (HLA-B7/EBNA3a379-387)

2005 Russ M

Journal ofImmunologicalMethods,Volume 304,Issues 1-2,September 2005,Pages 100-106

Photo-activatedaffinity-site cross-linking of antibodiesusing tryptophancontaining peptides

custompeptide

K-A-A-G-W containing a biotinmolecule on thealpha amino group (singlebiotin–peptide) and KA-A-K-G-E-A-K-A-A-G-W containingbiotin moleculeson the alpha and epsilon aminogroups oflysine (multiple biotin–peptide).

2005 Zhang X

Virology, Volume337, Issue 1, 20June 2005,Pages 162-174

Hsp72 recognizes aP binding motif inthe measles virus Nprotein C-terminus

custompeptide

2005 Kuang W-F

Biochemical andBiophysicalResearchCommunications, Volume 331,Issue 4, 17 June

Mutational andinhibitive analysis ofSARS coronavirus3C-like protease byfluorescenceresonance energy

custompeptide 1NC; 2NC

2005HutchinsonLM

ClinicalBiochemistry,Volume 38,Issue 6, June2005, Pages 558-571

Development of asensitive andspecific enzyme-linkedimmunosorbentassay for thymosin

custompeptide Tb4, Tb15, Tb16

2005 Dong X-N


Candidate multi-peptide-vaccineagainst classicalswine fever virusinduced potentimmunity withserological marker

custompeptide

Five overlapped peptides (Fig. 1)from unit B/C(aa693–777) on glycoprotein E2 ofCSFV strain Shimen (Sequencenumber in GenBank: AF092448)were commerciallysynthesised in Genemed SynthesisInc

2005VasudevanSA


MKP-8, a novelMAPK phosphatasethat inhibits p38kinase,

custompeptide anti-MKP-8

2005 Ko J-A

FEBS Letters,Volume 579,Issue 10, 11April 2005,Pages 2236-2242

Requirement of thetransmembranesemaphorinSema4C formyogenicdifferentiation

custompeptide

recombinant proteins were thenpurified with the use ofglutathione–Sepharose beads(Amersham, Piscataway, NJ).

Peptides were synthesized byGenemed Synthesis

2005 Yamagishi H

FEMSMicrobiologyLetters, Volume244, Issue 1, 1March 2005,

Saliva affects theantifungal activity ofexogenously addedhistatin 3 towardsCandida albicans

custompeptide Histatin 3

2005 Sun J-S

General andComparativeEndocrinology,Volume 141,Issue 1, March2005, Pages 48-57

Developmentalexpression ofFXPRLamideneuropeptides inpeptidergicneurosecretorycells of diapause-

custompeptide Har-DH

2005 Liu Z

ImmunologyLetters, Volume97, Issue 1, 15February 2005,Pages 41-45

Predefined spacersbetween epitopeson a recombinantepitope-peptideimpacted epitope-

custompeptide ELDKWA epitope peptide P1

2005 Hsu L-J


Cloning andcharacterization ofa small-size peptideZfra that regulatesthe cytotoxicfunction of tumor

custompeptide Zfra peptide

2005 Larabee JL


Cys redox reactionsand metal bindingof a Cys2His2 zincfinger

custompeptide

KKFACPECPKRFMSDHLSKHIKTHQNKK,

2005 Herring D

Neuropharmacology, Volume 48,Issue 2,February 2005,Pages 181-194

PKC modulation ofGABAA receptorendocytosis andfunction is inhibitedby mutation of adileucine motif

custompeptide

dileucine (ENILLSSTLEI) andcontrol dialanine(ENIAASSTLEI) peptides

2005 Toka FN

Virology, Volume331, Issue 1, 5January 2005,Pages 151-158

Rescue of memoryCD8+ T cellreactivity inpeptide/TLR9ligand immunization

custompeptide

MHC class-I-restrictedHSV-1 gB498–505 (SSIEFARL)

2005 Gong J-P

Neuroscience,Volume 132,Issue 3, 2005,Pages 713-727

Mouse brainlocalization of theprotein kinase C-enhancedphosphatase 1inhibitor KEPI

custompeptide

15-amino-acid peptide withsequence HQQGKVTVKYDRKELthat corresponded to residues66–80 of mKEPI protein

2005 Tai H-Y

Allergy, Volume61, Issue 3: 382-388. doi:10.1111/j.1398-9995.2005.00958.x

Pen ch 13 allergeninduces secretionof mediators anddegradation ofoccludin protein ofhuman lung

custompeptide

synthetic peptide, Occl-1, withsequence covering the secondextracellular loop of the humanoccluding (18) (residues 198–215,NPTAQSSGSLYGSQIYAL)

2005 Mujica AO

FEBS Journal,Volume 272,Issue 19: 4884-4898. doi:10.1111/j.1742-

Differentialexpression patternof the novelserine/threoninekinase, STK33, in

custompeptide

. Peptide synthesis and rabbitimmunization were performed byGenemed Synthesis (SanFrancisco, CA, USA).

2005 Jaseja M

Journal ofPeptideResearch,Volume 66,Issue 1: 9-18.

Structure–functionstudies of thefunctional andbinding epitope ofthe human 37 kDa

custompeptide

KGAHSVGLMWWMLAR(pepG15_hu) andRGKHSIGLIWYLLAR (pepG15_sa)

2005 Yang M-HImmunology;115: 279-286

Identification of T-cell epitopes onU1A protein inMRL/lpr mice:double-negative Tcells are the majorresponsive cells

custompeptide

These series of peptides,OVA323−339 and the histidine TAGcontrol peptides (32 amino acids)were synthesized and purified byhigh-performance liquidchromatography (HPLC) by theGenemed Synthesis Company

2005 Yu HX

Tissue Antigens,Volume 65,Issue 6: 539-543. doi:10.1111/j.1399-

A11 Tetramer-assistedcharacterization ofRta-specific CD8+T-cell responses in

custompeptide

2005Cruz-GarciaF


Stylar glycoproteinsbind to S-RNase invitro

custompeptide MAP conjugates

2005 Yamagishi H

FEMSMicrobiologyLetters, Volume244, Issue 1:207-212. doi:10.1016/j.femsle.2005.01.045

Saliva affects theantifungal activity ofexogenously addedhistatin 3 towardsCandida albicans

custompeptide

Histatin 3 (Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-Arg-Ser-Asn-Tyr-Leu-Tyr-Asp-Asn)

2005 Nishiyama YJ. Mol. Recog;18: 295–306

Broadly distributednucleophilicreactivity ofproteinscoordinated withspecific ligandbinding activity

custompeptide

EP1 bindingby synthetic Ser-Cys-Gln-Gly-Asp-Ser-Gly-Gly-Pro-Val-Val (corresponding to porcinetrypsin 190–200; purity,>95% by HPLC; m/z 1005.8 and1027.9 for the (MþH)þand (MþNa)þ peptide ions;Genemed Synthesis, SanFrancisco, CA, USA) wasdetermined

2005NaryzhnySN

J. Biol. Chem.,Apr 2005; 280:13888 - 13894.

Proliferating CellNuclear Antigen(PCNA) MayFunction as aDouble Homotrimer Miscl

plasmid pEGFPCNA , pT7hPCNA,pEGFPCNAL2PCNA Double TrimerFormation-Peptides

2005 Kohm AP

J. Immunol., Apr2005; 174: 4525 - 4534

Treatment withNonmitogenic Anti-CD3 MonoclonalAntibody InducesCD4+ T CellUnresponsivenessand FunctionalReversal of miscl

anti-CD3 Ab , anti-CD3(eBioscience), NM-IgG3 (20), and/orNM-F(ab')2 (Bio Express)

2005 Chen Y

J. Neurosci., Jan2005; 25: 507 -513

Specific Modulationof Na+ Channels inHippocampalNeurons by Protein miscl

peptide PKC translocation(EAVSLKPT, PKC-I) and scrambledpeptide (LSETKPAV

2005 Bender ATPNAS, Jan 2005;102: 497 - 502

Selective up-regulation ofPDE1B2 uponmonocyte-to-macrophagedifferentiation miscl

antigen. These residues arecommon to both PDE1B1 andPDE1B2 variants. PDE1B1- andPDE1B2-specific antisera wereproduced by Genemed Synthesis(South San Francisco, CA).Peptides corresponding to portionsof the unique N termini of PDE1B1and PDE1B2 were

2005 Kim BH

Microbiology,Jan 2005; 151:209 - 218

The formation ofcyclopropane fattyacids in Salmonellaenterica serovar miscl

restriction enzymes, T4 ligase andTaq polymerase

2005 Kim WJ

Journal ofControlledRelease, Volume106, Issues 1-2,

Soluble Flt-1 genedelivery using PEI-g-PEG-RGDconjugate for anti- miscl RGD peptide

2005 Shih S-C

Experimentaland MolecularPathology,Volume 79,

Quantitative multi-gene transcriptionalprofiling using real-time PCR with a miscl

2005 Yu H

HumanImmunology,Volume 66,Issue 5, May2005, Pages 483-

Identification ofCD8+ T-CellEpitopes Specificfor Immediate-EarlyTransactivator Rta miscl

2005 Yang Z

MolecularImmunology,Volume 42,Issue 9, May

Structure-baseddesign andcharacterization ofa Novel IL-6 miscl

2005 Kim A-R

ProteinExpression andPurification,Volume 40,

Two methods forlarge-scalepurification ofrecombinant miscl ChAT

2005 Barbas D

Journal ofNeurochemistry,Volume 96,Issue 2: 414-427. doi:

An aplysiadopamine1-likereceptor: molecularand functionalcharacterization miscl

2005 Konkel ME

MolecularMicrobiology,Volume 57,Issue 4: 1022-1035. doi:10.1111/j.1365-2958.2005.04744

Identification of afibronectin-bindingdomain within theCampylobacterjejuni CadF protein miscl

The CadF peptides weresynthesized on a semi-manualpeptide synthesizer using standardfluorenylmethoxycarbonyl chemistry(Genemed Synthesis,

2006SchowalterRM

J. Virol., Nov2006; 80: 10931 - 10941

Characterization ofHumanMetapneumovirusF Protein-PromotedMembrane Fusion:Critical Roles for

customantipeptideantibodies Antipeptide antibodies HMPV F

2006SusaimuthuJ

Plant Pathology,Volume 55,Issue 5: 607-613.

Yellow vein-affectedblackberries andthe presence of anovel Crinivirus

Customantipeptideantibodies

synthesizedpeptide -SDGHLAAKHGTTSQFWGATSDFTNG

2006 Small TW

Circ. Res., Dec2006; 99: 1338 -1346

Wilms’ Tumor1–AssociatingProtein Regulatesthe Proliferation of

customantipeptideantibodies WTAP antibody

2006 Qu S

Endocrinology,Dec 2006; 147:5641 - 5652

Aberrant ForkheadBox O1 Function IsAssociated withImpaired Hepatic


antibody FoxO1,Rabbit anti-GKantibody

2006 Liu Y

J. Biol. Chem.,Nov 2006; 281:34768 - 34774

Dimerization ofLaforin Is Requiredfor Its OptimalPhosphataseActivity, Regulationof GSK3

customantipeptideantibodies Epm2a cDNA

2006 Pasquet S

J. Biol. Chem.,Nov 2006; 281:34406 - 34420

TranscriptionEnhancer Factor-1-dependentExpression of the -Tropomyosin Gene

customantipeptideantibodies TEF-1 antibody

2006 Chin YR

J. Gen. Virol.,Nov 2006; 87:3161 - 3167

Adenovirus RIDcomplex enhancesdegradation ofinternalized tumournecrosis factorreceptor 1 without


anti-RIDb antibody,mouse anti-TNFR1 antibody

2006 Hill JK

J. Neurosci., Sep2006; 26: 9944 -9955.

Vestibular HairBundles Control pHwith (Na+, K+)/H+Exchangers NHE6

customantipeptideantibodies NHE6 and NHE9

2006 Ma A-H

Cancer Res.,Sep 2006; 66:8439 - 8447

Male GermCell–AssociatedKinase, a Male-Specific KinaseRegulated byAndrogen, Is a

customantipeptideantibodies MAK rabbit polyclonal antibody

2006 Rocnik EF

J. Biol. Chem.,Aug 2006; 281:22855 - 22864.

The Novel SPARCFamily MemberSMOC-2Potentiates

customantipeptideantibodies Antibody SMOC-2

2006 Wysocki J

Diabetes, Jul2006; 55: 2132 -2139

ACE and ACE2Activity in DiabeticMice

customantipeptideantibodies ACE2 antibody

2006Delgado-Lopez F

J. Virol., Jul2006; 80: 6378 -6386

Adenovirus RID ßComplex InhibitsLipopolysaccharideSignaling withoutAltering TLR4 CellSurface Expression


Anti-phosphoserine-536-p65 andanti-phospho-p38 , Horseradishperoxidase-conjugated anti-rabbitand anti-mouse immunoglobulin G ,mouse anti-TNFR1Polyclonalantibody for RIDß , Polyclonalantibodies against TNFR1, TLR4,FAS, IB, phospho-c-Jun, and ß-tu

2006 Chaurasia P

J. Biol. Chem.,May 2006; 281:14852 - 14863

A Region inUrokinasePlasminogenReceptor DomainIII Controlling aFunctionalAssociation with 51 Integrin andTumor Growth


Rabbit anti-uPAR polyclonalantibody , rabbit anti-lamininantibody, anti- alpha 5 bita1antibody (HA5),rabbit anti integrinalpha5,alpha 3 polyclonal antibodies, Anti-mouse IgG monoclonalantibody conjugated withhorseradish peroxidase (HRP),

2006Guevara-Patino JA

J. Clin. Invest.,May 2006; 116:1382 - 1390

Optimization of aself antigen forpresentation ofmultiple epitopes incancer immunity


Antibodies anti-CD8 mAb 53.6-72(rat IgG), anti-CD4 mAb (Gk1.5)and anti-NK mAb (PK136), Tyrp1peptides ,Tyrp1 cDNA

2006 Hanft LMPNAS, Apr 2006;103: 5385 - 5390.

Cytoplasmic -actincontributes to acompensatoryremodelingresponse indystrophin-deficient


Antibodies. pAbs ,mAbs , mouse Igs, Alexa Fluor 488 anti-mouse, AlexaFluor 568 anti-rabbit Igs, and AlexaFluor 568-conjugated phalloidin

2006BranhamMT

J. Biol. Chem.,Mar 2006; 281:8656 - 8666.

Calcium-inducedAcrosomalExocytosisRequires cAMPActing through aProtein Kinase A-independent, Epac-mediated Pathway


Epac peptide, Specific rabbitpolyclonal antibodies,rabbitpolyclonal anti-Rab3A (purified IgG), rabbit polyclonal anti-NSF ,Horseradish peroxidase-conjugatedgoat anti-rabbit-IgG (Fc fragment-specific) , TRITC-conjugated goatanti-rabbit IgG ,

2006 Siddiqi SA

J. Cell Sci., Mar2006; 119: 943 -950

Vesicle-associatedmembrane protein7 is expressed inintestinal ER

customantipeptideantibodies rat VAMP7

2006Phillips-Mason PJ

J. Biol. Chem.,Feb 2006; 281:4903 - 4910

The ReceptorProtein-tyrosinePhosphatase PTPµInteracts with


Polyclonal antibodiesIQGAP1,ERK2,phospho-p44/42MAPK ,Antibodies calmodulin

2006BuscagliaCA

J. Biol. Chem.,Jan 2006; 281:1324 - 1331

Characterization ofan Aldolase-bindingSite in the Wiskott-Aldrich SyndromeProtein


Antibodies—Goat anti-rabbitaldolase and rabbit anti-BloomSyndrome Protein , Rabbit anti-actin antibody , Rabbit antibodiesanti-human neural WASp (N-WASp), WASp, and p34 , WASpcDNA

2006 Cheng H

Cell, Volume127, Issue 7, 29December 2006,Pages 1389-1400

Human mRNAExport MachineryRecruited to the 5′End of mRNA


Rabbit antibodies to human CBP80,eIF4A3, and Y14 were raisedagainst the peptidesMSRRRHSDENDGGQPHKRR,ATSGSARKRLLKEED, andDESIHKLKEKAKKRKGRGFGSE,

2006 Wang Y

Cancer Cell,Volume 10,Issue 3,September 2006,

Epm2a suppressestumor growth in animmunocompromised host by inhibiting

customantipeptideantibodies anti-laforin polyclonal antibody

2006 Sakai T

Peptides,Volume 27,Issue 9,September 2006,Pages 2157-2164

Nutrient-induced α-amylase andprotease activity isregulated bycrustacean

customantipeptideantibodies rabbit anti-CCAP

2006 Li Y

J. Biol. Chem.,Nov 2006; 281:34048 - 34055

Biochemical,Molecular, andFunctionalCharacterization ofPISCF-Allatostatin,a Regulator of

CustomDNA Ae-AS-C cDNA

2006 Li XS

J. Biol. Chem.,Aug 2006; 281:22453 - 22463

Candida albicansCell Wall SsaProteins Bind andFacilitate Import ofSalivary Histatin 5

CustomOligo/DNA SSA1 and SSA2 cDNA

2006 Thomas S

Mol. Endocrinol.,Aug 2006; 20:1894 - 1911.

CalcitoninIncreasesTumorigenicity ofProstate CancerCells: Evidence forthe Role of Protein

CustomOligo/DNA CT cDNA

2006 Chang AYW

J. Physiol., Jul2006; 574: 547 -564.

Heat shock protein60 in rostralventrolateralmedulla reducescardiovascularfatality duringendotoxaemia inthe rat

CustomOligo/DNA

NCBI database, andoligonucleotides were synthesizedby Genemed Biotechnologies(Taipei, Taiwan). The primer pairsfor...NCBI database, andoligonucleotides were synthesizedby Genemed Biotechnologies(Taipei, Taiwan). The primer pairsfor......

2006 Ahmed ZM

J. Neurosci., Jun2006; 26: 7022 -7034

The Tip-LinkAntigen, a ProteinAssociated with theTransductionComplex of

CustomOligo/DNA

Antibodies. Mouse mAb G19 , Full-length mouse Pcdh15 poly(A)+ RNA

2006 Chavan MPNAS, Jun 2006;103: 8947 - 8952

Dimericorganization of theyeastoligosaccharyltransferase complex

CustomOligo/DNA

Triple Master DNA polymerase , T4DNA ligase and shrimp alkalinephosphatase , Anti-HA mAb HA.II ,Anti-Myc and anti-HA polyclonalantisera , Horseradish peroxidase(HRP)-labeled anti-rabbit IgG , Anti-FLAG (M2) affinity gel, affinity-purified monoclon

2006 Zagariya A

Pediatrics, May2006; 117: 1722 - 1727

Inhibition ofMeconium-InducedCytokineExpression andCell Apoptosis by

CustomOligo/DNA

polymerase chain reaction , ELISAkits

2006 Sasaki T

Mol. Cell. Biol.,Feb 2006; 26:1051 - 1062

The ChineseHamsterDihydrofolateReductaseReplication OriginDecision PointFollows Activationof Transcription

CustomOligo/DNA DHFR cDNA

2006 Fu Y-G

Cancer Letters,Volume 243,Issue 2, 18November 2006,Pages 246-254

Inhibition of gastriccancer cellsassociatedangiogenesis by15d-prostaglandin

CustomOligo/DNA cDNA

2006Gonzalez-Gronow M

Cancer Res.,Dec 2006; 66:11424 - 11431

Prostate CancerCell Proliferation Invitro Is Modulatedby Antibodiesagainst Glucose-Regulated Protein

custompeptide peptides GRP78

2006 Fife BT

J. Exp. Med.,Nov 2006; 203:2737 - 2747

Insulin-inducedremission in new-onset NOD mice ismaintained by the

custompeptide 1040-p31 peptide

2006 Huang L-R

PNAS, Nov2006; 103:17862 - 17867

Animmunocompetentmouse model forthe tolerance of

custompeptide

rHBcAg peptide, synthetic peptide,HBcAg 129-140

2006 Savoldo BBlood, Nov 2006;108: 2942 - 2949

Treatment of solidorgan transplantrecipients withautologous EpsteinBarr virus–specificcytotoxic Tlymphocytes (CTLs)

custompeptide

either Martin Campbell (SyntheticAntigen Laboratory, The Universityof Texas M. D. Anderson CancerCenter, Houston, TX) or GenemedSynthesis (South San Francisco,CA). In this paper, the peptides arereferred to by the first 3 amino acidsas underlined..

2006 Fuentes J

Am J PhysiolRegulatoryIntegrative CompPhysiol, Nov2006; 291:

Parathyroidhormone-relatedprotein regulatesintestinal calciumtransport in sea

custompeptide PTHrP 1-34 peptides

2006 Shen Y

J. Neurosci., Oct2006; 26: 10690 - 10699

Alternative Splicingof the CaV1.3Channel IQDomain, aMolecular Switchfor Ca2+-

custompeptide

synthetic peptide(GNSRSGKSKAWWGNTLRRTPRSPYRRD...peptide )

2006 Cui J

Cancer Res., Oct2006; 66: 10024 - 10031

c-Jun NH2-Terminal Kinase 22Promotes theTumorigenicity of

custompeptide

c-Jun NH2-Terminal Kinase 2 2,JNK22 and JNK2ß2 mRNAs

2006 Ilouz R

J. Biol. Chem.,Oct 2006; 281:30621 - 30630

Identification ofNovel GlycogenSynthase Kinase-3Substrate-interactingResidues Suggests

custompeptide

anti GSK-3,nti-phospho-GSK-3(Tyr216) , anti-phospho-CREB(Ser133) antibodies CREB antibody,anti-phospho--catenin, or -cateninantibody

2006 Chen Q

J. Biol. Chem.,Oct 2006; 281:31152 - 31163

The AminoTerminus of theHuman MultidrugResistanceTransporter ABCC1Has a U-shapedFolding with a

custompeptide

anti-FLAG monoclonal antibody,peroxidase- and fluoresceinisothiocyanate-conjugated goat anti-mouse IgG , Monoclonal antibodiesQCRL-1 and MRPr1, monoclonalanti-HA antibody

2006 Baroudi G

Am J PhysiolHeart CircPhysiol, Oct2006; 291:H1614 - H1622

Protein kinase Cactivation inhibitsCav1.3 calciumchannel at NH2-terminal serine 81

custompeptide

peptides N-MATAAPPPVGALAQRKRQQYAKAKKQGNAANARPA-C

2006KirschnerAN

J. Virol., Oct2006; 80: 9444 -9454.

Soluble Epstein-Barr VirusGlycoproteins gH,gL, and gp42 Forma 1:1:1 StableComplex That ActsLike Soluble gp42

custompeptide

Synthetic peptide gp42-36-65, 19-mer peptide(YKTKYLINSARLLETSMVD)

2006 Liao M

J. Virol., Oct2006; 80: 9599 -9607

Site-DirectedAntibodies againstthe Stem RegionReveal Low pH-InducedConformational

custompeptide

peptides stem1 and stem2,stem3and stem4 peptides

2006 Halm ST

Am J PhysiolCell Physiol, Oct2006; 291: C636- C648

Distinct K+conductivepathways arerequired for Cl– andK+ secretion acrossdistal colonicepithelium

custompeptide

48 h at 4C (20). A peptide wasgenerated with the identicalsequence employed to produceantiserum IK38/6(GGELVTGLGALRRRK; GenemedSynthesis, South San Francisco,CA), dissolved in water (0.6 mM),and used in controls of nonspecificinteractions of antis

2006 Maia LF

J. Biol. Chem.,Sep 2006; 281:29278 - 29286

Structure of aMembrane-bindingDomain from a Non-enveloped AnimalVirus: INSIGHTSINTO THEMECHANISM OF

custompeptide synthetic gamma1-peptide

2006 Basha S

PNAS, Sep2006; 103:13509 - 13513

Polyvalent inhibitorsof anthrax toxin thattarget hostreceptors

custompeptide

......scattering confirmed thepresence of vesicles (radius, 51 4nm). Peptides identified by phagedisplay were synthesized byGenemed Synthesis (South SanFrancisco, CA). These peptideswere acetylated at their N terminiand amidated at the C termini an

2006 Botten J

J. Virol., Sep2006; 80: 8351 -8361.

Identification ofProtective LassaVirus Epitopes ThatAre Restricted by

custompeptide HLA-A*0201-restricted peptide

2006NaccacheSN

PNAS, Aug2006; 103:12735 - 12740

Binding ofinternalizedreceptors to thePDZ domain ofGIPC/synectin

custompeptide 50 muM peptide

2006 Bai X-F

Cancer Res.,Aug 2006; 66:8241 - 8249.

Different Lineagesof P1A-ExpressingCancer Cells UseDivergent Modes ofImmune Evasionfor T-Cell Adoptive

custompeptide mutant P1A peptides

2006 Fife BTJ. Clin. Invest;116: 2252 - 2261

Inhibition of T cellactivation andautoimmunediabetes using a Bcell surface–linked

custompeptide

Antigens. DNP-OVA andDNP–keyhole limpet hemocyanin(DNP-KLH)

2006 Theos AC

Mol. Biol. Cell,Aug 2006; 17:3598 - 3612

Dual Loss of ERExport andEndocytic Signalswith AlteredMelanosome

custompeptide

Antibodies Anti-Pmel mAbs HMB-45, HMB-50, and NKI-betebRabbit antibody alpha Pep13h ,Rabbit antiserum alpha mPmel-N

2006 Majid AM

J. Virol., Jul2006; 80: 6993 -7008

EvaluatingReplication-Defective VesicularStomatitis Virus asa Vaccine Vehicle

custompeptide

mouse anti-E2 monoclonal antibody(MAb) H33 , anti-E2 MAb, H52.,MAb to E1, A4, Human anti-E2MAbs CBH-7 and CBH-8C ,Polyclonal rabbit anti-E2 , Mousecore MAb , Peptides- core (aa 133to 142), E1 (aa 315 to 322), and E2(aa 570 to 584)HCV (genoty

2006 Munks MW

J. Immunol., Jul2006; 177: 450 -458.

Four DistinctPatterns of MemoryCD8 T CellResponses to

custompeptide 8-mer, 9-mer and 10-mer peptides

2006 Xie Y

J. Biol. Chem.,Jun 2006; 281:16482 - 16492

Protein-tyrosinePhosphatase (PTP)Wedge DomainPeptides: A NOVELAPPROACH FORINHIBITION OFPTP FUNCTIONAND

custompeptide LAR and PTPµ Wedge Peptides ,

2006 Stanfield RL

J. Virol., Jun2006; 80: 6093 -6105

Crystal Structuresof HumanImmunodeficiencyVirus Type 1 (HIV-1) NeutralizingAntibody 2219 inComplex withThree Different V3

custompeptide

Human monoclonal antibody 2219 ,Eighteen V3 peptides , peptide,D687, Peptide VI191

2006 Takashi S

Am. J. Respir.Cell Mol. Biol.,Jun 2006; 34:647 - 652

A Peptide Againstthe N-Terminus ofMyristoylatedAlanine-Rich CKinase SubstrateInhibits

custompeptide MANS and RNS peptides

2006 Ramirez-Montagut T

J. Immunol., Jun2006; 176: 6434 - 6442

Glucocorticoid-Induced TNFReceptor FamilyRelated GeneActivationOvercomesTolerance/Ignoranc

custompeptide Peptides and ELISPOT Peptides

2006Kan-MitchelJ

J. Immunol., Jun2006; 176: 6690 - 6701

Degeneracy andRepertoire of theHuman HIV-1 Gagp1777–85 CTL

custompeptide IMGT Peptides

2006 Pochet S

Mol. Pharmacol.,Jun 2006; 69:2037 - 2046.

Modulation by LL-37 of theResponses ofSalivary Glands to

custompeptide peptides LL-37

2006SimpsonGIC

J. Biol. Chem.,May 2006; 281:14615 - 14621

Identification of theKey ResiduesResponsible for theAssembly of

custompeptide

Synthetic oligonucleotides ,Synthetic peptides , iodothyronines,

2006 Brann JH

J. Exp. Biol., May2006; 209: 1914 - 1927

Vomeronasalsensory neuronsfrom Sternotherusodoratus(stinkpot/muskturtle) respond to

custompeptide

TRPC2 and IP3R3 with the peptidesequence GSAGEGERVSYRLRVIK-ALVQRYIETARRE (905–934mTRPC2)

2006 Misra UK

J. Biol. Chem.,May 2006; 281:13694 - 13707.

Activation andCross-talk betweenAkt, NF- B, andUnfolded ProteinResponseSignaling in 1-LNProstate Cancer

custompeptide

Anti-GRP78 antibodies andglyceraldehyde-3-phosphatedehydrogenase antibodies,Controlsubstrate peptide Zak3tide andglutathione S-transferase-IalphaB-alpha substrate

2006 Michael IP

J. Biol. Chem.,May 2006; 281:12743 - 12750

Human TissueKallikrein 5 Is aMember of aProteolyticCascade PathwayInvolved in SeminalClot Liquefactionand Potentially inProstate Cancer

custompeptide

synthetic heptapeptides N-Ile-Gln-Ser-Arg-Ile-Val-Gly-C, N-Ile-Leu-Ser-Arg-Ile-Val-Gly-C, N-Ser-Cys-Ser-Gln-Ile-Ile-Asn-C, N-Ser-Ser-Ser-Arg-Ile-Ile-Asn-C, N-Glu-Gln-Asn-Lys-Leu-Val-His-C, N-Gln-Gly-Asp-Lys-Ile-Ile-Asp-C, N-Gln-Glu-Asp-Lys-Val-Leu-Gly-C,

2006 Kelleher SL

J. Nutr., May2006; 136: 1185 - 1191

ZincSupplementationReduces IronAbsorption throughAge-DependentChanges in Small

custompeptide hemocyanin-conjugated peptides

2006 Shiau C-W

J. Biol. Chem.,Apr 2006; 281:11819 - 11825.

-TocopherylSuccinate InducesApoptosis inProstate CancerCells in Part

custompeptide Flu-BakBH3, a Bak-BH3 peptide

2006MagadanJG

Mol. Cell. Biol.,Apr 2006; 26:2595 - 2614

Rab22a Regulatesthe Sorting ofTransferrin toRecycling

custompeptide anti-human TfnR antibody,anti-EEA1

2006 Munks MW

J. Immunol., Mar2006; 176: 3760 - 3766

Genome-WideAnalysis Reveals aHighly Diverse CD8T Cell Response toMurine

custompeptide 8-, 9-, and 10-mer peptides

2006 Ettinger RA

J. Immunol., Feb2006; 176: 1988 - 1998

Allelic Variation inKey Peptide-Binding PocketsDiscriminatesbetween CloselyRelated Diabetes-Protective and

custompeptide Applied Biosystems 432 Peptide

2006 Vylkova S

Antimicrob.AgentsChemother., Jan2006; 50: 324 -331.

Distinct AntifungalMechanisms: ß-Defensins RequireCandida albicansSsa1 Protein, whileTrk1p Mediates

custompeptide

Synthetic peptides Hst 5,LFcn11,BN 16,VPR 12,HNP-1,hBD-2,hBD-3

2006 Kuo Y-M

J. Nutr., Jan2006; 136: 21 -26.

BIOCHEMICAL,MOLECULAR,AND GENETICMECHANISMS:Copper TransportProtein (Ctr1)Levels in Mice Are

custompeptide antibody CTR1

2006Kaidanovich-Beilin O

J. Pharmacol.Exp. Ther., Jan2006; 316: 17 -24

Long-TermTreatment withNovel GlycogenSynthase Kinase-3Inhibitor ImprovesGlucoseHomeostasis in

custompeptide

biotin-conjugated peptide bio-L803-mts

2006Evel-KablerK

J. Clin. Invest.,Jan 2006; 116:90 - 100

SOCS1 restrictsdendritic cells’ability to break selftolerance andinduce antitumorimmunity by

custompeptide

peptides, TRP2,TRP2a,TRP2b, H2-Kb-restricted peptide

2006 Hsu P-H

OrganicGeochemistry,Volume 37,Issue 12,December 2006,Pages 1694-1704

Covalent couplingof peptides tohumic acids:Structural effectsinvestigated using2D NMRspectroscopy

custompeptide

Two N-labeled peptides with thesequenceSFFFYYS, with the threephenylalanines labeled,and SLLLVIS, with the threeleucines labeled,

2006Gomez-Nunez M

LeukemiaResearch,Volume 30,Issue 10,October 2006,Pages 1293-1298

Peptide bindingmotif predictivealgorithmscorrespond withexperimentalbinding of leukemia

custompeptide

2006 Hu S-Y

Aquaculture,Volume 260,Issues 1-4, 29September 2006,Pages 61-68

Structure andfunction ofantimicrobialpeptide penaeidin-5from the black tiger

custompeptide

cecropin A, cecropin B, magainin-II,penaeidin-5

2006 Li Y

Neuron, Volume51, Issue 6, 21September 2006,Pages 755-771

Modulation ofInactivationProperties ofCaV2.2 Channels

custompeptide anti-pS2126

2006 Kim WJ

Journal ofControlledRelease, Volume114, Issue 3, 12September 2006,

Anti-angiogenicinhibition of tumorgrowth by systemicdelivery of PEI-g-PEG-RGD/pCMV-

custompeptide RGD peptide

2006 Raikwar HPJ. Neuroimmuno;178: 76-86

PPARγ antagonistsreverse theinhibition of neuralantigen-specificTh1 response andexperimentalallergicencephalomyelitis

custompeptide

21 amino acid peptidecorresponding to mouse MOGp35-55

2006 Qin W

Journal ofBiotechnology,Volume 125,Issue 1, 20August 2006,Pages 57-63

De novo designTNF-α antagonisticpeptide based onthe complexstructure of TNF-αwith its neutralizing

custompeptide

de novo designed antagonizedpeptide; control peptide

2006 Zhang X


Zipzap/p200 is anovel zinc fingerprotein contributingto cardiac generegulation

custompeptide

2006 Hu J

Journal ofMolecularBiology, Volume361, Issue 1, 4August 2006,Pages 69-79

Structural Basis forPhosphotyrosineRecognition by theSrc Homology-2Domains of theAdapter Proteins

custompeptide

An 11-residue phosphopeptiderepresenting the murine Jak2pTyr813 site, TPDpYELLTEND

2006 Bergamin E

Structure,Volume 14,Issue 8, August2006, Pages

Structural Basis forPhosphotyrosineRecognition bySuppressor ofCytokine Signaling-

custompeptide

An11 residue phosphopeptiderepresenting murine gp130 pTyr757site

2006 Grzesiak JJ

Peptides,Volume 27,Issue 7, July2006, Pages1898-1901

Identification of DU145 prostatecancer cell proteinsthat bind to thecarboxy-terminal

custompeptide PTHrP(140-173)

2006 Li Y

ProteinExpression andPurification,Volume 47,Issue 2, June

Cloning,expression, isotopelabeling, andpurification ofhuman

custompeptide LL-37

2006 Yang M

Sensors andActuators B:Chemical,Volume 115,Issue 1, 23 May

Analysis ofinteractions oftemplate/primerduplexes with T7DNA polymerase

custompeptide

2006 Dong X-N


Spying theneutralizingepitopes on E2 N-terminal bycandidate epitope-

custompeptide BC1a, BC1b, BC1c, BC1d

2006 Dixon SJ

Biochimica etBiophysica Acta(BBA) -MolecularCell Research,Volume 1763,Issue 4, April

Trk receptorbinding andneurotrophin/fibroblast growth factor(FGF)-dependentactivation of the

custompeptide anti-Trk; anti-ERS3

2006 Dong X-N

Vaccine, Volume24, Issue 11, 10March 2006,Pages 1906-1913

Candidate peptide-vaccines inducedimmunity againstCSFV andidentified sequentialneutralizingdeterminants in

custompeptide

2006 Shao H

ExperimentalEye Research,Volume 82,Issue 2,February 2006,Pages 323-331

Severe chronicexperimentalautoimmune uveitis(EAU) of theC57BL/6 mouseinduced by adoptive

custompeptide

IRBP202-210; IRBP1177-1191;IRBP161-180

2006 Qin W

MolecularImmunology,Volume 43,Issue 6,

Fusion protein ofCDR mimeticpeptide with Fcinhibit TNF-α

custompeptide

PT (YINTGYDGLYYNSMD);randomized peptide

2006 Dong X-N

Vaccine, Volume24, Issue 4, 23January 2006,Pages 426-434

Candidate peptide-vaccine inducedpotent protectionagainst CSFV andidentified a principalsequential

custompeptide

Five overlapping peptides coveringamino acids 693–777(unit B/C) on glycoprotein E2 ofCSFV strain Shimen

2006CanarioAVM

FEBS Letters,Volume 580,Issue 1, 9January 2006,

Novel bioactiveparathyroidhormone andrelated peptides in

custompeptide puffer fish PTH/PTHrP(1-34)

2006 Hoenig M

Domestic AnimalEndocrinology,Volume 30,Issue 1, January2006, Pages 28-37

Cloning, expressionand purification offeline proinsulin

custompeptide

The sequence of the newlydesigned 5' primer was:5'-CTC CAT ATG TTC GTT AACCAG CAC CTG-3'; the sequence ofthe newly designed3' primer was: 5'-GCG GGA TCCCTA GTT GCA GTA GTG TTCCAG-

2006 Davis PH

Molecular andBiochemicalParasitology,Volume 145,Issue 1, January2006, Pages 111-116

Identification of afamily of BspA likesurface proteins ofEntamoebahistolytica withnovel leucine richrepeats

custompeptide

The derived amino acid sequence ofEhLRRP1 was used to identify threepotentially immunogenic peptides(TLLKSITIPSSISIKL (76-91);IEIPKNLKTINGKKIEKKDIN (334-354);FDGCPNELKKNEVLRKIYYKDD(531-552)) to produce EhLRRP1-specific rabbit antisera (GenemedSynth

2006 Bennett RJ

MolecularMicrobiology,Volume 62,Issue 1: 100-119. doi:

The role of nutrientregulation and theGpa2 protein in themating pheromoneresponse of C.

custompeptide

MF13 (GFRLTNFGYFEPG)and MF14 (GFRLTNFGYFEPG)

2006 Miao GB

Journal ofClinicalInvestigation,Volume 36,Issue 9: 614-620. doi:

Autoantibodyagainst β1-adrenergic receptorand left ventricularremodelingchanges in

custompeptide

2006 Li O

Scandinavian J.of Immunol; 64:117-124

CD62L is Requiredfor the Priming ofEncephalitogenic TCells but does notPlay a Major Rolein the Effector

custompeptide

Myelinoligodendrocyte glycoprotein (MOG)peptide 35-55(MEVGWYRSPFSRVVHLYRNGK)

2006 Nawrot M

PhotochemistryandPhotobiology, 82:1482-1488

Scaffold Proteinsand theRegeneration ofVisual Pigments

custompeptide

This assay was described previouslyin moredetail (10). In brief, samples oftissues were subjected to SDS-PAGE andtransferred to a PVDF sheet. Thesheet was incubated sequentiallywithCRALBP, anti-CRALBP, alkalinephosphatase coupled to antimouseorr

2006 Muthian GJ. Neurosci Res;83:1299–1309

1,25Dihydroxyvitamin-D3 ModulatesJAK–STATpathway in IL-12/IFNc AxisLeading to Th1Response in

custompeptide

The 13 amino acid peptide[HSLGKWLGHPDKF] correspondingto mouse PLPp139–151 wasobtained from Genemed SynthesisInc. (San Francisco, CA).

2006 Cohen AM

J. MassSpectrom. 41:646–658

Absolutequantification ofAtlantic salmon andrainbowtrout vitellogenin bythe ‘signaturepeptide’ approachusing electrosprayionization QqToFtandem massspectrometry

custompeptide

The standard peptide (purity > 95%)and itsdeuterated isotopic homolog(TYFAGA*A*A*DVLEVGVR,purity > 95% with A* being L-Alanine-3,3,3-d3) to beused as internal standard werepurchased from GenemedSynthesis (San Francisco,CA, USA).

2006 Carrillo A

J Polym Sci PartA: Polym Chem44: 928–939

BiofunctionalizedBlock CopolymerNanoparticlesBased on Ring-OpeningMetathesisPolymerization

custompeptide

The peptide(Ac-HTSTYWWLDGAPC-Am) wassynthesizedby Genemed Synthesis (South SanFrancisco,CA).

2006 Misri S

ExperimentalEye Research,Volume 83,Issue 5,

KCC isoforms in ahuman lensepithelial cell line(B3) and lens tissue miscl

2006 Spiess C

Molecular Cell,Volume 24,Issue 1, 6October 2006,Pages 25-37

Identification of theTRiC/CCTSubstrate BindingSites Uncovers theFunction of Subunit miscl Box2-C; Box1(AA)

2006 Nowis D

ExperimentalCell Research,Volume 312,Issue 15, 10September 2006,Pages 2921-2932

Destabilization ofthe VCP-Ufd1-Npl4complex isassociated withdecreased levels ofERAD substrates miscl

Polyclonalsera against human Ufd1, Npl4 andderlin-1 proteins werecustom-raised in rabbits afterimmunization with respectiveN-terminal peptides

2006 Park K


Expression andcharacterization ofconstitutively activehuman caspase-14 miscl

2006 Li X

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1758,

NMR studies ofaurein 1.2 analogs miscl

2006 Feng J

Biochimie,Volume 88,Issue 9,September 2006,Pages 1265-1273

The rationaldesignedantagonist derivedfrom the complexstructure ofinterleukin-6 and itsreceptor affectively miscl

2006 Jr

Virus Research,Volume 120,Issues 1-2,September 2006,Pages 146-155

Inhibition of severeacute respiratorysyndrome-associatedcoronavirus (SARS-CoV) infectivity by miscl

N-alpha-9flourenylmethyloxycarbonyl

2006 Kalman K


AQP0-LTR of theCatFr mouse alterswater permeabilityand calciumregulation of wild miscl

2006 Kale AY

Brain ResearchBulletin, Volume70, Issue 3, 31July 2006, Pages240-244

Effects of acuteand chronic insulin-inducedhypoglycemia ontype IIglucocorticoid miscl

2006 Brown AG

Peptides,Volume 27,Issue 7, July2006, Pages1794-1800

A hemoglobinfragment found incervicovaginal fluidfrom women inlabor potentiatesthe action of agents miscl

2006 Tang C-J C

DevelopmentalBiology, Volume290, Issue 2, 15February 2006,Pages 398-410

Dynamiclocalization andfunctionalimplications ofAurora-C kinaseduring male mousemeiosisDevelopmental miscl MAPs (multiple antigenic peptides)

2006 Saxena SK


Rab4 GTP/GDPmodulatesamiloride-sensitivesodium channel(ENaC) function in miscl ENaC

2006 Butowt R

Molecular andCellularNeuroscience,Volume 31,Issue 1, January

Anterograde axonaltransport of theexogenous cellularisoform of prionprotein in the chick miscl

2007 Whitman SD

Virology, Volume363, Issue 2, 5July 2007, Pages419-429

Surface density ofthe Hendra Gprotein modulatesHendra F protein-promotedmembrane fusion:

Customantipeptideantibodies Hendra F antipeptide antibodies

2007 Zhu Z


PI3K is negativelyregulated byPIK3IP1, a novelp110 interactingprotein


polyclonal antibody made in rabbitagainst PIK31P1 peptide

2007Hernández-Martínez S

Journal of InsectPhysiology,Volume 53,Issue 3, March2007, Pages 230-234

Role of juvenilehormone andallatotropin onnutrient allocation,ovariandevelopment andsurvivorship inmosquitoes


Rabbit polyclonal antisera againstAe. aegypti AT was produced usinga synthetic peptide (Veenstra andCostes, 1999) conjugated toKeyhole limpet hemocyanin byGenemed Synthesis, Inc. (SanFrancisco, CA).

2007 Wang F

Aging Cell,OnlineEarlyArticles.Published articleonline: 23-May-2007doi:

SIRT2 deacetylatesFOXO3a inresponse tooxidative stress andcaloric restriction


Rabbit anti-SIRT3 antibody wasraised against the C-terminus 15amino acid residues of mouseSIRT3 (DLMQRERGKLDGQDR) bythe Genemed Synthesis, Inc. (SouthSan Francisco, CA, USA).

2007 Tufail M

Archives ofInsectBiochemistry andPhysiology66:190–203

Evidence for TwoVitellogenin-Related Genes inLeucophaeamaderae: TheProtein PrimaryStructureand Its Processing


Rabbit anti-LmVg1 and -LmVg2antibodies weredirected against the last 20 aminoacid residues(Genemed Synthesis, Inc.) of thethird stretch havingdifferent amino acid sequences

2007RayapuramC

The PlantJournal; 52,700–715

Increased SA inNPR1-silencedplants antagonizesJA andJA-dependentdirect and indirectdefenses inherbivore-attackedNicotiana attenuatain nature


To isolate polyclonal antibodiesagainst Na-NPR1, a 15-amino-acidpeptide was synthesized using thecDNA sequence of Na-NPR1 (N’-CKG/ARP/SDL/TSD/GRK-C’). Thispeptide was used to immunize arabbit, and anti-serum against thesynthesized peptide wasobtai

2007MashalovaEV

HEPATOLOGY;;45:755-766

Prevention ofHepatocyteAllograft Rejectionin Ratsby TransferringAdenoviral Early


rabbit antiserato RID (1:500; GenemedSynthesis Inc.

2007 Kong W

JOURNAL OFCELLULARPHYSIOLOGY210:153–160

Cyclophilin C-Associated ProteinIs Up-RegulatedDuring WoundHealing


Polyclonal antibody was producedby Genemed Synthesis,Inc. (South San Francisco, CA). Thepeptide, SYKYRQFYTYNYGSQ,from the CyCAP hypothetical proteinsequence(GenBank accession AF065438)was synthesized and injectedinto rabbits for antibody generatio

2007 Qu S

Am J PhysiolEndocrinolMetab, Feb2007; 292: E421 -

PPAR mediates thehypolipidemicaction of fibrates byantagonizing FoxO1

customantipeptideantibodies FoxO1 peptide,rabbit IgG antibody

2007 Tan Y

Mol. Cell. Biol.,Feb 2007; 27:1007 - 1016.

Chk2 MediatesStabilization of theFoxM1TranscriptionFactor To Stimulate

customantipeptideantibodies FoxM1 peptide antibody

2007 Sivertson KL

CellularImmunology, InPress, CorrectedProof, Availableonline 14 June2007,

The differentialeffect ofdexamethasone ongranulocyteapoptosis involvesstabilization of Mcl-


A 15 aminoacid peptide(RGPRRWHQECAAGFC,corresponding toamino acids 239–253

2007 Qu S

Am J PhysiolEndocrinolMetab, Feb2007; 292: E421 - E434.

PPAR mediates thehypolipidemicaction of fibrates byantagonizing FoxO1


Polyclonal rabbit anti-FoxO1antibody was developed in ourlaboratory by immunization ofrabbits with the glutathione S-transferase-tagged human FoxO1protein (Genemed Synthesis, SanFrancisco, CA)

2007 Krenz M

J. Biol. Chem.,Jun 2007;10.1074/jbc.M704574200.

MOLECULARBASIS OF CELLANDDEVELOPMENTALBIOLOGY:Distribution andstructure-functionrelationship of


custom-made polyclonal anti-loop-2of cardiac β-MHC

2007 Chen Y-IG

Nucleic AcidsRes., May 2007;10.1093/nar/gkm347

Proteomic analysisof in vivo-assembled pre-mRNA splicingcomplexesexpands the


Polyclonal antisera directed againstthe carboxyl-terminal15 amino acids of KIAA0332 andNP_035897 (NCBIaccession numbers)

2007 Hou F

J. Cell Biol., May2007; 177: 587 -597

Theacetyltransferaseactivity of Sanstabilizes themitotic cohesin atthe centromeres in


The polyclonal rabbit antibody tohuman San was raised by GenemedSynthesis, Inc. using His-taggedrecombinant San as the antigen

2007 Zhang X

Gene, Volume400, Issues 1-2,1 October 2007,Pages 131-139

Alternative splicingand nonsense-mediated mRNAdecay regulategene expression ofserum responsefactor


Anantibody against a peptidesequence SQCRPFKCTRPHSKRderived from the putative proteinsequence of exon 4 in SRF-▵3was generated by standardprocedure

2007 Krenz M

J. Biol. Chem.,Aug 2007; 282:24057 - 24064.

Distribution andStructure-FunctionRelationship ofMyosin HeavyChain Isoforms in


polyclonal anti-loop 2 of cardia beta-MHC

2007 Xie Z

J. Biol. Chem.,Aug 2007; 282:25278 - 25289

Group VIAPhospholipase A2(iPLA2) Participatesin Angiotensin II-inducedTranscriptional Up-regulation of

customantipeptideantibodies iPLA2 beta antibody

2007Gustafson-Wagner EA

Am J PhysiolHeart CircPhysiol, Nov2007; 293:H2680 - H2692.

Loss of mXin, anintercalated diskprotein, results incardiac hypertrophyand


polyclonal antibodies (U1697 for apeptide specific and U1741 for bpeptide specific)

2007 Penuela S

J. Cell Sci., Nov2007; 120: 3772 - 3783

Pannexin 1 andpannexin 3 areglycoproteins thatexhibit manydistinctcharacteristics from


...used to generate site-directedrabbit polyclonal antibodies byGenemed Synthesis

2007 Lee MT

Eukaryot. Cell,Dec 2007; 6:2406 - 2418

Endocytosis in theShiitake MushroomLentinula edodesand Involvement of

customantipeptideantibodies LeRAB7 polyclonal antiserum

2007 Gautam A

Microbiology,Jan 2008; 154:275 - 285

Analysis of thedeterminants ofbba64 (P35) geneexpression inBorrelia burgdorferi

customantipeptideantibodies anti-RpoS Ab

2007 Chan JYH

J. Biol. Chem.,Feb 2007; 282:4585 - 4600

Heat Shock Protein60 or 70 ActivatesNitric-oxideSynthase (NOS) I-and Inhibits NOS II-associatedSignaling andDepresses the

CustomOligo/DNA hsp60 cDNA

2007 Henke MO

Am. J. Respir.Crit. Care Med.,Jan 2007;doi:10.1164/rccm.200607-1011OC

MUC5AC andMUC5B MucinsIncrease in CysticFibrosis AirwaySecretions During

CustomOligo/DNA MUC5AC and MUC5B

2007 Scarselli M

J. Biol. Chem.,Jan 2007;doi:10.1074/jbc.M610394200

Multiple residues inthe secondextracellular loopare critical for M3muscarinicacetylcholinereceptor activation

CustomOligo/DNA

under error-prone conditions (30).The following sense primer codingfor M3R residues Pro-201 to Phe-232 was synthesized by GenemedSynthesis Inc. (San Francisco, CA):5'-CCT GCC ATC TTG TTC TGGCAA TAC TTT GTA GGG AAGAGA ACT GTG CCC CCA GGAGAA TGT TTC.

2007 Thelin WR

J. Clin. Invest.,Feb 2007; 117:364 - 374

Direct interactionwith filaminsmodulates thestability and plasmamembraneexpression of CFTR

CustomOligo/DNA

Peptides corresponding to residues1–25 of CFTR were synthesizedfollowed by a serine-glycine-serine-gylcine (SGSG) linker region and aC-terminal lysine residue coupled tobiotin (Genemed Synthesis

2007 Chen Y-I G

Nucleic AcidsRes., June 2007;35: 3928 - 3944

Proteomic analysisof in vivo-assembled pre-mRNA splicingcomplexes

CustomOligo/DNA

carboxyl terminal 15 amino acids ofKIAA0332 and NP_035897

2007Krautz-Peterson G

J. Biol. Chem.,Jul 2007; 282:21767 - 21775.

Amino AcidTransport inSchistosomes:CHARACTERIZATION OF THEPERMEASEHEAVY

CustomOligo/DNA

SPRM1hc amno acid residues 615-633


J. Biol. Chem.,Nov 2007; 282:32811 - 32820

PlasminogenStructural DomainsExhibit DifferentFunctions WhenAssociated withCell Surface

CustomOligo/DNA Ser759-Arg778

2007 Schaefer DCell, Jun 2007;6: 907 - 918.

Barrier Activity inCandida albicansMediatesPheromoneDegradation and

custompeptide

Alpha pheromone peptide(GFRLTNFGYFEPG) wassynthesized by Genemed Synthesis.

2007 Botten J

J. Virol., Mar2007; 81: 2307 -2317

LA-A2-RestrictedProtection againstLethal LymphocyticChoriomeningitis

custompeptide

......unique LCMV isolates for whichamino acid sequences have beenreported. Peptides. Peptides (90%pure) were obtained from GenemedSynthesis, Inc. (South SanFrancisco, CA). Hepatitis B virus(HBV) ENV 378 (LLPIFFCLWV)was used as an irrelevant, HLA-A

2007 Mishra S

J. Biol. Chem.,Feb 2007; 282:4288 - 4300

Activation of JNK-dependent PathwayIs Required for HIVViral Protein R-induced Apoptosisin HumanMonocytic Cells:INVOLVEMENT

custompeptide Vpr Peptides

2007McMullanLK

PNAS, Feb2007;doi:10.1073/pnas.0611267104

Evidence for afunctional RNAelement in thehepatitis C virus

custompeptide 4050 peptides

2007DeshmukhPA

Am J PhysiolHeart CircPhysiol, Feb2007; 292: H792- H799

Acute modulationof PP2a andtroponin Iphosphorylation inventricular

custompeptide PP2a peptide

2007 Thelin WR

J. Clin. Invest.,Feb 2007; 117:364 - 374.

Direct interactionwith filaminsmodulates thestability and plasmamembrane

custompeptide

CFTR1-25 or CFTR1-25/S13Fpeptides

2007 Cabbage SE

J. Immunol., Jan2007; 178: 887 -896

Regulatory T CellsMaintain Long-Term Tolerance toMyelin BasicProtein by Inducing

custompeptide MBP121-140 or MBPAc1-11 peptide

2007GusarovaGA

J. Clin. Invest.,Jan 2007; 117:99 - 111

A cell-penetratingARF peptideinhibitor of FoxM1in mousehepatocellular

custompeptide

WT ARF26-44 peptide or mutantARF37-44 peptide

2007 Drake WP

Infect. Immun.,Jan 2007; 75:527 - 530

CellularRecognition ofMycobacteriumtuberculosis ESAT-6 and KatG

custompeptide ESAT-6 and KatG peptide

2007 Li Y

ProteinExpression andPurification,Volume 54,Issue 1, 1 July

A novel method forpurifyingrecombinanthuman hostdefense cathelicidin

custompeptide synthetic LL-37

2007LawrencePK

VeterinaryImmunology andImmunopathology, In Press,Accepted

CD11b of Oviscanadensis andOvis aries:molecular cloningand characterization

custompeptide

2007 Bernabeu A


Structure of the C-terminal domain ofthe pro-apoptoticprotein Hrk and itsinteraction with

custompeptide

synthetic peptide encompassingresidues 65-91 of Hrk

2007 Lopez M

Biochemical andBiophysicalResearchCommunications, Volume 356,Issue 4, 18 May

Moleculararchitecture ofleishmania EF-1αreveals a novel sitethat may modulateprotein translation:

custompeptide synthetic peptide (EKVRFIPIS)

2007Chockalingam A

VeterinaryMicrobiology, InPress, CorrectedProof, Availableonline 18 May2007,

A peptide derivedfrom humanbactericidal/permeability-increasingprotein (BPI) exertsbactericidal activityagainst Gram-negative bacterialisolates obtainedfrom clinical casesof bovine mastitis

custompeptide

peptide[(KWKAQKRFLKKSKVGWLIQLFHKK)(MW: 3027 g/mol)] corresponding totwodiscontinuous regions of sequencewithin the matureform of human BPI [amino acids90–99 (underlined)and 148–161]

2007 Li Y

ProteinExpression andPurification, InPress,UncorrectedProof, Availableonline 10 May

On-resin cleavageof bacteriallyexpressed fusionproteins forpurification of activerecombinantpeptides SK-29, KR-

custompeptide synthetic peptide KR-20

2007 Li A


Atomic forcemicroscopy study ofthe antimicrobialaction of Sushipeptides on Gram

custompeptide

2007 Castro FR

Toxicon, Volume49, Issue 3, 1March 2007,Pages 299-305

The effect oftreatment withcrotapotin on theevolution ofexperimental

custompeptide Peripheral myelin P2 (58-81) peptide

2007 Laskin J

nternationalJournal of MassSpectrometry, InPress, CorrectedProof, Available

Charge retention bypeptide ions soft-landed onto self-assembledmonolayer surfaces

custompeptide

2007 Yu J


Identification of acomplementreceptor 1 peptidefor inhibition ofimmune hemolysis

custompeptide CR1 peptide

2007 Berg KA

Neuroscience,Volume 144,Issue 3, 9February 2007,

Integrins regulateopioid receptorsignaling intrigeminal ganglion

custompeptide

blocking peptides for anti-MOR andanti-phospho-Pyk-2

2007 Wei X

InternationalJournal ofBiologicalMacromolecules,Volume 40,Issue 2, 30

Design and stabilityof a novel coiled-coil peptide

custompeptide

emplate of natural protein, a novelpeptide was designed with satisfiedstability which came from theformation of coiled-coil dimer in vitro

2007 Levy R

Journal ofMolecularBiology, Volume365, Issue 1, 5January 2007,

Fine and Domain-level EpitopeMapping ofBotulinumNeurotoxin Type A

custompeptide N-KYVDVNNVGIRGYMYLKGP-C

2007 Wu XR


Altered expressionof plant lysyl tRNAsynthetasepromotes tRNAmisacylation and

custompeptide

C-terminal EESAAAQAPLTEEKK-specific sequences of At-KRS-1

2007 Brintnell W

ScandinavianJournal ofImmunology,Volume 65,Issue 5: 444-452. doi:

The Influence ofMHC Class IIMoleculesContaining theRheumatoidArthritis Shared

custompeptide

Eight peptides were selected fromthe G1 region of aggrecan (Table 1)and synthesized by GenemedSynthesis

2007 Wang Y

Journal ofNeurochemistry,OnlineEarlyArticles.Published articleonline: 30-Apr-2007

Brain-derivedneurotrophic factorstimulates thetranscriptional andneuroprotectiveactivity of myocyte-enhancer factor 2C

custompeptide

MEF2C S192 peptide(GVTHRPPSAG) and MEF2CS192Apeptide (GVTHRPPAAG)

2007 Gagnon KB

Clinical andExperimentalPharmacologyand Physiology,OnlineEarlyArticles.Published articleonline: 26-Apr-

CHARACTERIZATION OF ANEXTRACELLULAREPITOPEANTIBODY TOTHE NEURONALK-ClCOTRANSPORTER

custompeptide

extracellular (IFKAEDASGEAAAML)polypeptide sequence derivedfrom the second extracellular loop(ECL2) of rat KCC2 wassynthesized ontoa lysine backbone

2007 Thomas AH

ExperimentalBiology andMedicine, Mar2007; 232: 406 -411.

A BRIEFCOMMUNICATION: CollagenFragmentsModulate InnateImmunity

custompeptide

Ten milligrams of peptide p1 (Lot#10054791, Genemed SynthesisInc., San Francisco, CA), p2 (Lot#10059702, Genemed SynthesisInc.), and p3 (Lot #10059701,Genemed Synthesis Inc.)

2007 Getts MT

J. Virol., Jun2007; 81: 6584 -6593

DifferentialOutcome ofTolerance Inductionin Naive versusActivated Theiler's

custompeptide

All synthetic peptides were obtainedfrom Genemed Synthesis

2007SchaubertKL

Immunol., Jun2007; 178: 7756 - 7766.

Availability of aDiversely AvidCD8+ T CellRepertoire Specificfor theSubdominant HLA-A2-Restricted HIV-1 Gag p2419–27Epitope J.

custompeptide

The HIV-1 peptides TLNAWVKVV(TV9, Gag p2419–27), TLNAWVKVI(9I), TLNAWVKLV (HIV-2 Gag, 8L),SLYNTVATL (SL9, Gag p1777–85),SLFNTVATL (3F), SLYNTVAAL(SL9 agonist, p41), ILKEPVHGV(IV9, Pol476–484), the influenzamatrix peptide GILGFVFTL (GL9,Flu MP58–66

2007 Bover LC

J. Immunol., Jun2007; 178: 8183 - 8194

A PreviouslyUnrecognizedProtein-ProteinInteraction betweenTWEAK andCD163: Potential

custompeptide

CWDDGWSFC (CD163-likepeptide) and CRKFRDEATC (usedas a control peptide) werepurchased from Genemed Synthesis

2007 Embers ME

Clin. VaccineImmunol., Jun2007;10.1128/CVI.00075-07

The C6 DiagnosticPeptide of BorreliaburgdorferiContains DominantEpitopes That AreLargelyInaccessible toAntibody on the

custompeptide

Peptides used for the followingexperiments(sequences shown inTable 1, all derived from V1sE of B.burgdorferi strain B31) consisted offree peptides and N-terminal biotin-conjugated peptides.

2007 Munks MW

Infection J.Immunol., Jun2007; 178: 7235 - 7241

Viral Interferencewith AntigenPresentation DoesNot Alter Acute orChronic CD8 T CellImmunodominance

custompeptide

All 8-, 9-, and 10-mer peptides weresynthesized as crude peptides(65–95% pure by HPLC) byGenemed Synthesis or JeriniPeptide Technologies

2007 Freitas MS

J. Biol. Chem.,Jun 2007;10.1074/jbc.M611864200.

Structure of theEbola fusionpeptide in amembrane-mimeticenvironment andthe interaction withlipid rafts

custompeptide

Ebola fusion domain The fusionpeptide EBO16(GAAIGLAWIPYFGPAA) comprisesthe fusion domain of an internalsequence located in theenvelope fusion glycoprotein (GP2)of the Ebola virus.

2007Krautz-Peterson G

J. Biol. Chem.,Jun 2007;10.1074/jbc.M703512200

Amino acidtransport inschistosomes:Characterization ofthe permease

custompeptide

NH2-IDQPVGSQRVYLKSDGQPM-COOH

2007YatsenkoAS

J. Biol. Chem.,May 2007; 282:15159 - 15169

A Putative SrcHomology 3Domain BindingMotif but Not the C-terminal DystrophinWW DomainBinding Motif Is

custompeptide

Six additional tetramethylrhodamine-labeled peptides were ordered fromGenemed Synthesis Inc

2007 Savoldo B

Blood, May2007;10.1182/blood-2006-11-059139

Epstein barr virus-specific cytotoxic Tlymphocytesexpressing the anti-CD30 artificialchimeric T-cellreceptor for

custompeptide

For some experiments, the CMVpeptides A2-NLV and B7-TPR wereused. Peptides were synthesized byGenemed Synthesis

2007 Chu H-Y

Mol. Cell. Biol.,May 2007; 27:3743 - 3749

Cloning andFunctional Analysisof HypothalamicHomeobox GeneBsx1a and ItsIsoform, Bsx1b

custompeptide

Anti-BSX1A and anti-BSX1B serawere produced by immunizingrabbits with synthesized peptides,FPHPQ HAELP GKHCR and C-LRPGE KVRNP ALPVD,respectively (Genemed Synthesis).

2007 Liu J-QJ. Immunol; 178:6227 - 6235

CD24 on theResident Cells ofthe CentralNervous SystemEnhancesExperimentalAutoimmune

custompeptide

The immunogen, myelinoligodendrocyte glycoprotein MOGpeptide 35–55(MEVGWYRSPFSRVVHLYRNGK),was purchased from GenemedSynthesis

2007HumphreysIR

J. Exp. Med.,May 2007; 204:1217 - 1225

Cytomegalovirusexploits IL-10–mediatedimmune regulation

custompeptide

MCMV-derived peptides (GenemedSynthesis Inc.).

2007 Qu S

J. Lipid Res., Apr2007;10.1194/jlr.M600498-JLR200

Effects of apoA-Von HDL and VLDLmetabolism inAPOC3 transgenic

custompeptide

mouse apoAVspecific peptide (amino acids 113-128, VGWNLEGLRQQLKPYT)

2007 Pouliot K

Infect. Immun.,Apr 2007;10.1128/IAI.01644-06

Evaluation of therole of LcrV/TLR2-mediatedimmunomodulationin the virulence ofYersinia pestis

custompeptide

Synthetic LcrV peptides (purified byhigh-pressure liquidchromatography to >98%) werepurchased from GenemedSynthesis, Inc.

2007 Kirkland JG

Am J PhysiolGastrointestLiver Physiol,Apr 2007;10.1152/ajpgi.00425.2006.

AGONISTS OFPROTEASE-ACTIVATEDRECEPTORS 1AND 2STIMULATEELECTROLYTESECRETIONFROM MOUSEGALLBLADDER

custompeptide

APs corresponding to the tetheredligand of mouse PAR1 (SFLLRN-NH2), Xenopus PAR1 (TFLLRN-NH2), and mouse PAR2 (SLIGRL-NH2) and their respective reversesequences (NRLLFS-NH2, NRLLFT-NH2, and LRGILS-NH2), whichwere used as inactive controls, werefrom Ge

2007 Few WP

PNAS, Mar2007; 104: 5187 - 5192

Dopaminemodulation ofneuronal Na+channels requiresbinding of A kinase-anchoring protein15and PKA by a

custompeptide

AKAP15 LZ peptide (37-ENAVLKAVQQYLEETQN-55) and AKAP15 LZM peptide (37-ENAVAKAVQQYAEETQN-55) weresynthesized and preparedby Genemed Synthesis Inc.

2007 Dang Y

Clin. CancerRes., Mar 2007;13: 1883 - 1891

TumorAntigen–Specific T-Cell Expansion IsGreatly Facilitated

custompeptide

HER-2/neu peptides weresynthesized by Genemed Synthesis

2007 Scarselli M

J. Biol. Chem.,Mar 2007; 282:7385 - 7396

Multiple Residuesin the SecondExtracellular LoopAre Critical for M3MuscarinicAcetylcholine

custompeptide

The following sense primer codingfor M3R residuesPro201 to Phe232 was synthesizedby Genemed Synthesis

2007 Botten J

J. Virol., Mar2007; 81: 2307 -2317

HLA-A2-RestrictedProtection againstLethal LymphocyticChoriomeningitis

custompeptide

Peptides (90% pure) were obtainedfrom Genemed Synthesis

2007 Nash KT

J Natl CancerInst, Feb 2007;99: 309 - 321

Requirement ofKISS1 Secretion forMultiple OrganMetastasisSuppression andMaintenance ofTumor Dormancy

custompeptide

cells were exposed for 5 minutes tocombinations of chemicallysynthesized ligands for variousreceptors. These ligands includedKP-10 (100 nM; Genemed Synthesis

2007McMullanLK

PNAS, Feb2007; 104: 2879 - 2884.

Evidence for afunctional RNAelement in thehepatitis C viruscore gene

custompeptide

Peptide stimulation was conductedby using 10 pools of 40–50 peptides(Genemed Synthesis)

2007 Mishra S

J. Biol. Chem.,Feb 2007; 282:4288 - 4300

Activation of JNK-dependent PathwayIs Required for HIVViral Protein R-induced Apoptosisin HumanMonocytic Cells:INVOLVEMENT

custompeptide

Vpr peptides were synthesized byGenemed Synthesis

2007 Turley DMJ. Immunol; 178:2212 - 2220

PeripheralTolerance InductionUsingEthylenecarbodiimide-Fixed APCs Usesboth Direct andIndirectMechanisms ofAntigen

custompeptide

Synthetic peptides MOG35–55(MEVGWYRSPFSRVVHLYRNGK),PLP139–151 (HSLGKWLGHPDKF),and Eα52–68(ASFEAQGALANIAVDKA) werepurchased from GenemedSynthesis.

2007DeshmukhPA

Am J PhysiolHeart CircPhysiol, Feb2007; 292: H792- H799

Acute modulationof PP2a andtroponin Iphosphorylation inventricularmyocytes: studieswith a novel PP2a

custompeptide

he peptides (see Table 1; GenemedSynthesis, San Francisco, CA) werein the permeabilization solution at aconcentration of 0.15 µg/µl unlessotherwise note

2007 Cabbage SE

J. Immunol., Jan2007; 178: 887 -896

Regulatory T CellsMaintain Long-Term Tolerance toMyelin BasicProtein by Inducinga Novel, DynamicState of T Cell

custompeptide

Proliferation in response to an invivo MBP peptide pulse wasmeasured following i.v. injection of0.4 µmoles MBP121–140 orMBPAc1–11 (control) peptide(Genemed Synthesis).

2007GusarovaGA

J. Clin. Invest.,Jan 2007; 117:99 - 111

A cell-penetratingARF peptideinhibitor of FoxM1in mousehepatocellularcarcinoma

custompeptide

WT ARF26–44peptide(rrrrrrrrrKFVRSRRPRTASCALAFVN) or mutant ARF37–44 peptide(rrrrrrrrrSCALAFVN),

2007 Drake WP

Infect. Immun.,Jan 2007; 75:527 - 530

CellularRecognition ofMycobacteriumtuberculosis ESAT-6 and KatGPeptides in

custompeptide

ESAT-6 and KatG peptide wassynthesizedby solid-phase 9-fluorenylmethoxycarbonyl (Fmoc)chemistry

2007 Vylkova S

Chemother., Jan2007; 51: 154 -161

Human DefensinsKill Candidaalbicans in anEnergy-Dependentand Salt-SensitiveManner withoutCausing Membrane

custompeptide

Hst 5 was synthesized by usingstandard solid-phase synthesisprotocols and purified by reversed-phase high-performance liquidchromatography by GenemedSynthesis Inc

2007 Li Y

ProteinExpression andPurification,Volume 54,Issue 1, 1 July

A novel method forpurifyingrecombinanthuman hostdefense cathelicidin

custompeptide LL-37

2007 Shannon D

Virology, Volume363, Issue 2, 5July 2007, Pages419-429

Surface density ofthe Hendra Gprotein modulatesHendra F protein-promotedmembrane fusion:Role for Hendra Gprotein trafficking

custompeptide Hendra F, Hendra G

2007 Verde M.A.

ComparativeBiochemistry andPhysiology - PartA: Molecular &IntegrativePhysiology,

Pigment dispersinghormone generatesa circadianresponse to light inthe crayfish,Procambarus clarkii

custompeptide PDH

2007 Laskin J

InternationalJournal of MassSpectrometry,Volume 265,Issues 2-3, 1September 2007,Pages 237-243

Charge retention bypeptide ions soft-landed onto self-assembledmonolayer surfaces

custompeptide

MARK polyclonal antibodies wereproduced in rabbits against aMARK C-terminal peptide(KNIASKIANELKL) (GenemedSynthesis, South San Francisco,CA, USA), which corresponded totherat MARK sequence from aminoacids 781–793 (referred to asa-MARK) and the N

2007 Li Y

ProteinExpression andPurification,Volume 55,Issue 2, October2007, Pages 395-405

On-resin cleavageof bacteriallyexpressed fusionproteins forpurification of activerecombinantpeptides SK-29, KR-

custompeptide KR-20

2007 Xu X

Journal ofMolecularBiology, Volume373, Issue 2, 19October 2007,Pages 367-381

The PeriplasmicBacterial MolecularChaperone SurAAdapts its Structureto Bind Peptides inDifferentConformations toAssert a Sequence

custompeptide OmpF, OmpG

2007 Vavaiya K

Brain Research,Volume 1176, 24October 2007,Pages 62-70

Caudal hindbrainlactate infusionalters glucokinase,SUR1, andneuronal substratefuel transportergene expression inthe dorsal vagalcomplex, lateralhypothalamic area,

custompeptide PCR primers

2007 Liao Y


Cloning of a pighomologue of thehuman lactoferrinreceptor:Expression andlocalization during

custompeptide LfR anti-serum

2007 Christenn M

FEBS Letters,Volume 581,Issue 27, 13November 2007,

Interaction of brainsomatostatinreceptors with thePDZ domains of

custompeptide

Synthetic peptides (Fig. 1A) wereobtained from Genemed Synthesis

2007Chockalingam A

VeterinaryMicrobiology,Volume 125,Issues 1-2, 15November 2007,Pages 80-90

A peptide derivedfrom humanbactericidal/permeability-increasingprotein (BPI) exertsbactericidal activityagainst Gram-negative bacterial

custompeptide human BPI [amino acids 90–99

2007 Karnoup AS

Journal ofChromatographyB, Volume 859,Issue 2, 15

A novelHPLC–UV–MSmethod forquantitative

custompeptide

EEQYNSTYR (“N”) andEEQYDSTYR(“D”)

2007 Stokely M

J. NeurosciMeth; 166: 217-228

Microfluorimetrydefines earlyaxonal damage in arat model of opticneuritis: A novel

custompeptide MOG-peptide 35-55

2007 Li J

J. ofNeuroimmuno;192: 57-67

High cell surfaceexpression of CD4allows distinction ofCD4+CD25+antigen-specificeffector T cellsfrom CD4+CD25+regulatory T cells in

custompeptide

mog peptide p35-55, mbp peptideAc1-11

2007 Wang G

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1768,Issue 12,

Determination ofsolution structureand lipid micellelocation of anengineeredmembrane peptide

custompeptide pepA, pepB

2007Cruzeiro-Silva C


Structural biology ofmembrane-actingpeptides:Conformationalplasticity of

custompeptide PW2

2007 Wu F


Characterization ofimmunity inducedby M2e of influenzavirus

custompeptide M2 protein

2007 Li P

Journal ofEndotoxinResearch, June2007; 13: 150 -157.

RecombinantFactor C competesagainst LBP to bindlipopolysaccharideand neutralizes the

custompeptide LBP85108 peptide 23, 35

2007 Scharfer D

Eukaryot. Cell,Jun 2007; 6: 907- 918

Barrier Activity inCandida albicansMediatesPheromone

custompeptide

0.4 potassium phosphate, 2mannitol alpha pheromone peptide

2007 Munks MW

J. Immunol., Jun2007; 178: 7235 - 7241

Viral Interferencewith AntigenPresentation DoesNot Alter Acute orChronic CD8 T CellImmunodominance

custompeptide

Peptides All 8-, 9-, and 10-merpeptides

2007 Bover LC

J. Immunol., Jun2007; 178: 8183 - 8194

A PreviouslyUnrecognizedProtein-ProteinInteraction betweenTWEAK and

custompeptide CWDDGWSFC, CRKFRDEATC

2007SchaubertKL

J. Immunol., Jun2007; 178: 7756 - 7766

Availability of aDiversely AvidCD8+ T CellRepertoire Specificfor theSubdominant HLA-

custompeptide

matrix peptide GL9, Flu MP58-66and tyrosinase368-376 peptide YV9

2007 Pouliot K

Infect. Immun.,Jul 2007; 75:3571 - 3580

Evaluation of theRole of LcrV-Toll-Like Receptor 2-MediatedImmunomodulation

custompeptide synthetic LcrV peptides

2007 Kirkland JG

Am J PhysiolGastrointestLiver Physiol, Jul2007; 293: G335- G346

Agonists ofprotease-activatedreceptors 1 and 2stimulate electrolytesecretion from

custompeptide NH2

2007 Qu S

J. Lipid Res., Jul2007; 48: 1476 -1487.

Effects of apoA-Von HDL and VLDLmetabolism inAPOC3 transgenic

custompeptide mouse apoA-V-specific peptide

2007Mitra-Kaushik S

J. Immunol., Jul2007; 179: 1303 - 1312

Human CytotoxicCD4+ T CellsRecognize HLA-DR1-RestrictedEpitopes onVaccinia VirusProteins A24R and

custompeptide

The top 45 predicted bindingpeptides were selected for synthesisas 21-mer peptides, of which 36peptides were successfullysynthesized by Genemed Synthesis

2007 Jenkins S.A.

Endocrinology,Aug 2007; 148:3914 - 3921

Administration ofAdrenocorticotropicHormone duringChicken EmbryonicDevelopmentPrematurely

custompeptide cACTH, cACTH 1-24

2007 Embers ME

Clin. VaccineImmunol., Aug2007; 14: 931 -936

Dominant Epitopesof the C6Diagnostic Peptideof Borreliaburgdorferi AreLargely

custompeptide

N terminal biotin-conjugatedpeptides

2007 May RJ

Clin. CancerRes., Aug 2007;13: 4547 - 4555.

Peptide Epitopesfrom the Wilms'Tumor 1OncoproteinStimulate CD4+and CD8+ T CellsThat Recognize

custompeptide

Each of the peptides used in thisstudy was purchased andsynthesized by Genemed Synthesis,

2007

J Am OsteopathAssoc, Aug2007; 107: 327 -

51st Annual AOAResearchConference—Abstra

custompeptide PKC peptides, epsilon, beta II+zeta

2007HumphreysIR

J. Immunol., Aug2007; 179: 2195 - 2202

OX40CostimulationPromotesPersistence ofCytomegalovirus-

custompeptide MCMV peptides

2007 Freitas MS

J. Biol. Chem.,Sep 2007; 282:27306 - 27314.

Structure of theEbola FusionPeptide in aMembrane-mimeticEnvironment and

custompeptide Ebola fusion domain

2007 Savoldo BBlood, Oct 2007;110: 2620 - 2630

Epstein Barrvirus–specificcytotoxic Tlymphocytesexpressing the anti-CD30 artificialchimeric T-cell

custompeptide CMV peptides A2-NLV and B7-TPR

2007 Genesca M

J. Immunol., Oct2007; 179: 4732 - 4740.

Live AttenuatedLentivirus InfectionElicitsPolyfunctionalSimianImmunodeficiencyVirus Gag-SpecificCD8+ T Cells withReduced Apoptotic

custompeptide 9- and 10-mer peptides

2007 Madison MN

Infect. Immun.,Oct 2007; 75:4780 - 4791

Human Defensin -1CausesTrypanosoma cruziMembrane PoreFormation andInduces DNA

custompeptide defensin a-1

2007 Bollard CMBlood, Oct 2007;110: 2838 - 2845

Completeresponses ofrelapsed lymphomafollowing geneticmodification oftumor-antigen

custompeptide synthesized peptides

2007 Zhao P

Clin. CancerRes., Oct 2007;13: 6049 - 6055

Identification of aMet-BindingPeptide from aPhage Display

custompeptide

nonavid peptide and their FITC andbiotin conjugates

2007 Nishiyama Y

J. Biol. Chem.,Oct 2007; 282:31250 - 31256.

Towards CovalentVaccination:IMPROVEDPOLYCLONAL HIVNEUTRALIZINGANTIBODYRESPONSE

custompeptide reversed phase HPLC

2007GodovikovaV

J. Biol. Chem.,Oct 2007; 282:31341 - 31348

DynamicProcessing ofRecombinantDentin Sialoprotein-

custompeptide Rat DSP peptide

2007 Lapteva N

Cancer Res.,Nov 2007; 67:10528 - 10537

EnhancedActivation ofHuman DendriticCells by InducibleCD40 and Toll-likeReceptor-4 Ligation

custompeptide

HLA-A2–restricted peptides MAGE-3-A2.1 p271-279 (FLWGPRALV),influenza matrix p58-66(GILGFVFTL), and HIV-1 gag p77-85 (SLYNTVATL) were used toanalyze CD8+ T-cell responses. InTh cell polarization experiments,HLA-DR11.5–restricted tetanustoxoid peptid

2007 Carlisle J

Clinical andExperimentalImmunology,150: 460–468

MultipleMycobacteriumantigens induceinterferon-gproductionfrom sarcoidosisperipheral bloodmononuclear cells

custompeptide

The amino acid sequences for the17 ESAT-6 peptides,15-mers overlapping by 10, weresynthesized as describedpreviously [16].We tested forimmune recognition of all 17peptides in this analysis, as well astwo katG peptides, basedupon a previous report

2007 Bailey SL

NatureImmunology; 8:172 - 180

CNS myeloid DCspresentingendogenous myelinpeptides'preferentially'polarize CD4+ TH-17 cells in relapsingEAE

custompeptide

CNS mDCs presentedendogenously acquired peptide,driving the .... F1) were immunizedwith MOG(35–55) or withOVA(323–339) (control). .....(MEVGWYRSPFSRVVHLYRNGK)were synthesized by GenemedSynthesis

2007 Ramos SJAutoimmunity;40: Pages 54-65

Anti-viral effector Tcell responses andtrafficking are notdependent uponDRAK2 signalingfollowing viralinfection of thecentral nervoussystem

custompeptide

2007 Zeng Y

Brazilian J. MedBio Res; 40:1003-1010

Baicalin reducesthe severity ofexperimentalautoimmuneencephalomyelitis

custompeptide

mmunodominant mouse PLP139-151 peptide (HSLGKWLGHPDKF)was synthesized by Genemedsynthesis (South San Francisco,CA, USA), purity was assessed byHPLC (>97%).

2007 Vylkova S

Antimicrob.AgentsChemother., Jan2007; 51: 154 -161

Human ß-Defensins KillCandida albicans inan Energy-Dependent andSalt-SensitiveManner withoutCausing MembraneDisruption miscl

by using standard solid-phasesynthesis protocols and purified byreversed-phase high-performanceliquid chromatography by GenemedSynthesis Inc. (San Francisco, CA).The primary structures of thesepeptides are shown in Table 1.Candidacidal assay......

2007 Verde MA


Pigment dispersinghormone generatesa circadianresponse to light inthe crayfish,Procambarus clarkii miscl PDH

2007 Huleatt JW

Vaccine, Volume25, Issue 4, 8January 2007,Pages 763-775

Vaccination withrecombinant fusionproteinsincorporating Toll-like receptor miscl LL)(91-99); p60(217-225)

2007 Balabanov RJ. Neurosci; 27:2013 - 2024

Interferon--OligodendrocyteInteractions in theRegulation ofExperimentalAutoimmune miscl

Eachimmunized mouse received 200 gof MOG35–55(MEVGWYRSPFSRVVHLYRNGK) (Genemed Synthesis,

2007 Tan Y

Mol. Cell. Biol.,Feb 2007; 27:1007 - 1016

Chk2 MediatesStabilization of theFoxM1TranscriptionFactor To Stimulate miscl

The anti-phosphoserine 361 FoxM1peptide antibody (FoxM1 pS361)was generated and affinity purifiedby Genemed Synthesis

2007 Colin S.B.

Vaccine, Volume25, Issue 29, 20July 2007, Pages5330-5342

Immunologicalvalidation of theEpitOptimizerprogram forstreamlined design miscl

2007 Chen MJ

Journal ofCellularBiochemistry101:1316–1327

Suppression ofGrowth and Cancer-InducedAngiogenesis ofAggressive HumanBreast CancerCells (MDA-MB-231) on theChorioallantoic Miscl

SynthetichEb-peptide was purchased fromGenemedSynthesis, Inc. (South SanFrancisco, CA).

2007 Qin JJ. Neurosci Res;85: 977–984

OxidizedPhosphatidylcholineIs a MarkerforNeuroinflammationin Multiple Miscl

Each immunized mouse received200 lg of MOG35–55 (MEVGWYRSPFSRVVHLYRNGK; Genemed Synthesis,Inc., San Francisco, CA)

2008 Boateng K

Mol Plant, Jul2008; 1: 620 -633.

SWI1 Is Requiredfor MeioticChromosomeRemodeling Events


A peptide to amino acids from 85 to105 (HFDYSRMNRNKPMKKRSGG)of SWI1 was synthesized, coupledto KLH, and also used to produce arabbit polyclonal antiserum(Genemed Synthesis Inc.).

2008 Myoung J

J. Virol., Jun2008; 82: 5606 -5617.

AnticapsidImmunity Level, NotViral PersistenceLevel, Correlateswith theProgression ofTheiler's Virus-


Synthetic peptides and antibodies.All peptides were purchased fromGeneMed Synthesis Inc.

2008Bailey-Bucktrout S

J. Immunol; 180:6457 - 6461.

Cutting Edge:Central NervousSystemPlasmacytoidDendritic CellsRegulate the


Peptides and antibodies PLP139-151 (HSLGKWLGHPDKF) wassynthesized to 95% purity byGenemed Synthesis

2008 Zhang Y

J. Biol. Chem.,May 2008; 283:12730 - 12735

Identification ofRegulatory FactorX as a NovelMismatch Repair


Antibody, Antibody Depletion, andWestern Blot-An antibody to EXO1

2008Simsek-Duran

Neuropharmacology, Volume 55,Issue 1, July

The role of RIM1αin BDNF-enhancedglutamate release


pSer447-RIM1α antibody we havedeveloped.

2008 Ramirez GR


Nuclear andNuclear EnvelopeLocalization ofDystrophinDp71 andDystrophin-Associated Proteins(DAPs) inthe C2C12 MuscleCells: DAPsNuclear


The following antibodies were used:þ78 Dp71, a rabbit polyclonalantibody directed against the last 17amino acids of the C-terminaldomain of dystrophin (antibodysynthesized by Genemed Synthesis,Inc. San Francisco, CA andcharacterized in our laborato

2008 Nie J

STEM CELLS2008;26:2735–2745

IFATS Collection:CombinatorialPeptides Identify5 1 Integrin as

a Receptor for theMatricellular ProteinSPARC on Adipose


or antisera against cyclizedKLH-coupled peptides produced inrabbits (1:100; Genemed SynthesisInc., San Francisco,http://www.genemedsyn.com).

2008 Misra U


HeterotrimericGaq11 Co-ImmunoprecipitatesWith Surface-Anchored GRP78From PlasmaMembranes ofa2M*-StimulatedMacrophages


Antibodies against MTJ-1 wereraisedagainst the sequence beginning atresidue 105,NH2-LVAIYEVLKVDERRQRYVDVL-COOH,of MTJ-1 (SWISS-PROT, primaryaccession noQ61712) in rabbits (GenemedSynthesis)

2008March DiazR

The PlantJournal; 53,475–487

Histone H2A.Z andhomologues ofcomponents of theSWR1complex arerequired to controlimmunity inArabidopsis


antibody (raised in rabbits againstthe QDSPQDYLRVHNQARC PR1peptide; Genemed Synthesis, Inc.;http://www.genemedsyn.com) aspreviously described (March-Diaz etal., 2007).

2008 Zheng J

General andComparativeEndocrinology,Volume 155,Issue 3, 1February 2008,Pages 780-788

Studies of areceptor guanylylcyclase clonedfrom Y-organs ofthe blue crab(Callinectessapidus), and itspossible functionallink toecdysteroidogenesis


antipeptide antibodies (anti-CsGC-YO1) were raised against afragment of the extracellular domainof CsGC-YO1. Western blotsshowed affinity purified anti-CsGC-YO1 bound to the heterologouslyexpressed extracellular domain, andto a protein in Y-organs th

2008 Van Laar VS

Neurobiology ofDisease, Volume29, Issue 3,March 2008,Pages 477-489

Proteomic analysisof rat brainmitochondriafollowing exposureto dopamine

customantipeptideantibodies MtCK, anti-mitofilin antybody

2008 Kornilayev B

Toxicology inVitro, Volume 22,Issue 3, April2008, Pages 779-787

Utility of polyclonalantibodies targetedtoward uniquetryptic peptides inthe proteomicanalysis of


2008 Miller CL

Brain ResearchBulletin, InPress,UncorrectedProof, Available

The high-affinityniacin receptorHM74A isdecreased in theanterior cingulate


antibodies to distinguish HM74 andHM74 A

2008 Liu R-Y

J. Neurosci., Feb2008; 28: 1970 -1976

cAMP ResponseElement-BindingProtein 1 FeedbackLoop Is Necessaryfor Consolidation ofLong-Term

customantipeptideantibodies anti-tCREB1 antibodies

2008 Koga Y

Mol. Biol. Cell,Mar 2008; 19:1062 - 1071

A Novel RegulatoryMechanism ofMyosin Light ChainPhosphorylation viaBinding of 14-3-3 to

customantipeptideantibodies anti-pSer472 polyclonal antibody

2008 Koulich E

Mol. Biol. Cell,Mar 2008; 19:1072 - 1082

Relative Structuraland FunctionalRoles of MultipleDeubiquitylatingProteins Associated

customantipeptideantibodies anti-Usp14 polyclonal antibody

2008 Pinthong M

Mol. Pharmacol.,Mar 2008; 73:801 - 812.

Activity andSubcellularTrafficking of theSodium-CoupledCholine

customantipeptideantibodies polyclonal antibody against CHT

2008 Wi LJ. Biol. Chem;283: 6968 - 6978.

Identification of aNew Co-factor,MOG1, Requiredfor the Full Functionof Cardiac Sodium

customantipeptideantibodies anti-MOG1 antibodies

2008 Hala M

PLANT CELL,May 2008;doi:10.1105/tpc.108.059105

An ExocystComplex Functionsin Plant Cell Growthin Arabidopsis andTobacco


Polyclonal anti-At SEC8 was raisedby synthesis of a peptide (C-LREELARIDESWAAA)corresponding to amino acids 16 to30 of the predicted Arabidopsisprotein, conjugation of the peptide toKLH via the N-terminal Cys (C),immunization of rabbits using a stan

2008 Wang Y

Cancer Res.,Jun 2008; 68:4039 - 4044

Laforin ConfersCancer Resistanceto EnergyDeprivation–Induce

customantipeptideantibodies anti-laforin polyclonal antibody

2008 Boateng K

Mol Plant, Jun2008;doi:10.1093/mp/ssn030

SWI1 Is Requiredfor MeioticChromosomeRemodeling Events


SWI1 was synthesized, coupled toKLH, and also used to produce arabbit polyclonal antiserum

2008 Miller C

Brain ResearchBulletin, Volume77, Issue 1, 5September 2008,Pages 33-41

The high-affinityniacin receptorHM74A isdecreased in theanterior cingulatecortex of individuals


); two polyclonal antibodiesthat were custom-generated throughGeneMed Synthesis (South SanFrancisco,CA)

2008 Liu R

Mol. Cell. Biol.,Dec 2008; 28:7236 - 7244.

Laforin NegativelyRegulates CellCycle Progressionthrough GlycogenSynthase Kinase


The primary antibodies wereantilaforin (Genemed Synthesis,Inc., San Francisco, CA)

2008 Fioravante D

J. Neurosci., Oct2008; 28: 10245 - 10256.

TheUbiquitin–Proteasome System IsNecessary for Long-Term Synaptic


both antibodies were raised by acommercial vendor (GenemedSynthesis)

2008 Yu Y

J. Biol. Chem.,Sep 2008; 283:24497 - 24505.

Phosphorylation ofThr-178 and Thr-184 in the TAK1 T-loop Is Required forInterleukin (IL)-1-mediated OptimalNFB and AP-1Activation as Wellas IL-6 Gene


antibody was generated byimmunizing rabbits with thesynthetic phosphopeptidecorresponding to amino acidsVLKICDFGpTACDIQpTHM (wherepT represents phosphothreonine) ofhuman TAK1 by GenemedSynthesis,

2008 Gutierrez M

J. Immunol., Aug2008; 181: 2651 - 2663.

TNF-B ActivationControlsPhagolysosomeFusion-MediatedKilling ofMycobacteria by


Rabbit affinity-purified Ab anti-Rab34 was purchased fromGenemed Synthesis and generatedusing a specific peptide.

2008 Fenske S

J. Biol. Chem.,Aug 2008; 283:22097 - 22104.

Overexpression ofthe PDZ1 Domainof PDZK1 Blocksthe Activity ofHepatic ScavengerReceptor, Class B,Type I by AlteringIts Abundance andCellular Localization


The rabbit polyclonal antibody wasprepared against a 30-mer amino-terminal peptide from the murinePDZK1 protein sequence, coupledto keyhole limpet hemocyanin(Genemed Synthesis, South SanFrancisco, CA),

2008 Lee C

Nucleic AcidsRes., Aug 2008;36: 4708 - 4718.

Human DDX3functions intranslation andinteracts with thetranslation initiationfactor eIF3


A rabbit polyclonal antibody wasraised against an N-terminal peptide[ENALGLDQQFAGLDLNSSDNQS(Genemed Synthesis, Inc., TX)]

2008 Wang Y

Cancer Res.,Jun 2008; 68:4039 - 4044.

Laforin ConfersCancer Resistanceto EnergyDeprivation–Induce


Anti-laforin polyclonal antibody wasproduced by Genemed Synthesis,Inc.

2008 Zhang Y

J. Biol. Chem.,May 2008; 283:12730 - 12735.

Identification ofRegulatory FactorX as a NovelMismatch RepairStimulatory Factor


Antibody, Antibody Depletion, andWestern Blot-An antibody to EXO1was generated by GenemedSynthesis (San Antonio, TX),

2008 Hála M

PLANT CELL,May 2008; 20:1330 - 1345.

An ExocystComplex Functionsin Plant Cell Growthin Arabidopsis and


affinity purification of the antibodyagainst the peptide on a column(Genemed Synthesis).

2008 Luo G

J. Biol. Chem.,Apr 2008; 283:10433 - 10444.

The SphingolipidLong-chain Base-Pkh1/2-Ypk1/2Signaling PathwayRegulatesEisosomeAssembly andTurnover


Rabbit polyclonal antibodies wereraised against the C terminus of Pil1(CVGHQQSESLPQQTTA) andLsp1 (CHHVSQNGHTSGSENI,Genemed Synthesis Inc., SanFrancisco, CA)

2008 Wu LJ. Biol. Chem;283: 6968 - 6978

Identification of aNew Co-factor,MOG1, Requiredfor the Full Functionof Cardiac Sodium


Two anti-MOG1 antibodies weredeveloped by GeneMed Synthesis,Inc.

2008 Pinthong M

Mol. Pharmacol.,Mar 2008; 73:801 - 812.

Activity andSubcellularTrafficking of theSodium-CoupledCholine


The polyclonal antibody againstCHT was raised in rabbits byGenemed Synthesis (SanFrancisco, CA)

2008 Koga Y

Mol. Biol. Cell,Mar 2008; 19:1062 - 1071.

A Novel RegulatoryMechanism ofMyosin Light ChainPhosphorylation viaBinding of 14-3-3 toMyosinPhosphatase


rabbit anti-pSer472 polyclonalantibody (VIRSAphosphoSSPRLS:amino acids 467-477 of Rat MYPT1)were prepared by GenemedSynthesis (South San Francisco, CA)

2008PeremyslovV

Plant Physiology,Mar 2008; 146:1109 - 1116.

Two Class XIMyosins Function inOrganelleTrafficking andRoot HairDevelopment inArabidopsis


Rabbit polyclonal antiserum againstsynthetic oligopeptideAFSEAEARNSELATELENA-TRKAD corresponding to the aminoacid residues 936 to 959 ofthe deduced sequence of theArabidopsis myosin XI-K wascustom-made byGenemed Synthesis

2008 Liu R

J. Neurosci., Feb2008; 28: 1970 -1976.

cAMP ResponseElement-BindingProtein 1 FeedbackLoop Is Necessaryfor Consolidation ofLong-Term


The anti-tCREB1 antibodies wereraised by a commercial vendor(Genemed Synthesis, South SanFrancisco, CA)

2008 Callahan M

PNAS, Feb2008; 105: 1662 - 1667.

Heat-shock protein90 associates withN-terminalextended peptidesand is required fordirect and indirectantigen presentation


epitope II (223-231; CKGVNKEYL),SHL8 (SIINFEHL), and 18-merSHL8 (LEQLKSIINFEHLKEWTS)were synthesized by GenemedSynthesis

2008 Emami N

J. Biol. Chem.,Feb 2008; 283:3031 - 3041

Human Kallikrein-related Peptidase14 (KLK14) Is aNew ActivatorComponent of theKLK ProteolyticCascade:

CustomOligo/DNA

N-Glu-Ser-Ser-Lys-Val-Leu-Asn-C,N-Asp-Glu-Asn-Lys-Ile-Ile-Gly-C,and N-Asp-Gly-Asp-Lys-Leu-Leu-Glu-C

2008PeremyslovVV

Plant Physiology,Mar 2008; 146:1109 - 1116

Two Class XIMyosins Function inOrganelleTrafficking and

CustomOligo/DNA

amino acid residues 936 to 959 ofthe deduced sequence of theArabidopsis myosin XI-K

2008 Fernandes F

Biophys. J., Apr2008; 94: 3065 -3073

Role of Helix 0 ofthe N-BAR Domainin MembraneCurvatureGeneration

CustomOligo/DNA

H0-NBAR-FITC(fluoresceinisothiocyanate), and H0-ENTH(epsin N-terminal homologydomain)

2008 Kursula P

Journal ofMolecularBiology, Volume375, Issue 1, 4January 2008,Pages 270-290

High-resolutionStructural Analysisof MammalianProfilin 2a ComplexFormation with TwoPhysiologicalLigands: TheFormin Homology 1

custompeptide VASP, mDia1

2008 Zhang Q

Peptides,Volume 29,Issue 2,February 2008,Pages 196-205

Diapause hormonein the cornearworm,Helicoverpa zea:Optimumtemperature foractivity,

custompeptide Hevir-DH, Hezea-DH

2008 Tuteja R

Molecular andBiochemicalParasitology,Volume 157,Issue 2,

Plasmodiumfalciparum signalpeptidase isregulated byphosphorylation

custompeptide Y(NO2)

2008 Lu L

Vaccine, Volume26, Issue 6, 6February 2008,Pages 845-852

V3 CTL epitopedensity in a singlerecombinantmolecule antigendifferentially affectsthe number and

custompeptide

2008 Aldrich MVaccine; 26:1128-1135

SOCS1downregulation indendritic cellspromotes memoryT-cell responses

custompeptide

H2-Kb-restricted TRP2(VYDFFVWL), H2-Kb-restricted OT-I(chicken ovalbumin [OVA] peptide257—264, SIINFEKL) andOT-II chicken (OVA peptide 323-339, ISQAVHAAHAEINEAGR),

2008 Banerjee M

Peptides,Volume 29,Issue 3, March2008, Pages 375-385

Probing theconformation anddynamics ofallatostatinneuropeptides: A

custompeptide allatostatin

2008Perez-Berna A

Biochimica etBiophysica Acta(BBA) -Biomembranes,In Press,

The pre-transmembraneregion of the HCVE1 envelopeglycoprotein:

custompeptide E1PTM

2008Simsek-Duran F

Neuropharmacology, In Press,Corrected Proof,Available online

The role of RIM1αin BDNF-enhancedglutamate release

custompeptide R1M1a peptide

2008 Moreno MR


Biophysicalcharacterizationand membraneinteraction of themost

custompeptide

g terminal amide, n terminalacetylation

2008 Yuan L

EuropeanJournal ofPharmaceuticsandBiopharmaceutics, In Press,

Reversiblelipidization ofsomatostatinanalogues for theliver targeting

custompeptide Tyr3-Octreotide

2008 Hoppe M

The Journal ofNutritionalBiochemistry, InPress, CorrectedProof, Available

Hepcidin,interleukin-6 andhematological ironmarkers in malesbefore and after

custompeptide human hepcidin peptide,

2008CarpentierPA

Virology, Volume375, Issue 1, 25May 2008,Pages 24-36

Pro-inflammatoryfunctions ofastrocytes correlatewith viral clearanceand strain-dependent

custompeptide vp3(159-166), vp2 (121-130)

2008DinamarcaMC

Chemico-BiologicalInteractions, InPress, AcceptedManuscript,Available online

Release ofAcetylcholinesterase (AChE) from β-amyloid plaquesassembliesimproves the

custompeptide Ab(1-42) peptide

2008 Mangano K

Journal ofNeuroimmunology, Volume 196,Issues 1-2, 30

Preventive andcurative effects ofcyclophosphamidein an animal model

custompeptide myelin protein P0

2008 Lin K-W

The InternationalJournal ofBiochemistry &Cell Biology,Volume 40,

Protease-activatedreceptor-2 (PAR-2)is a weak enhancerof mucin secretionby human bronchial

custompeptide

PAR-2 activating peptide AP, andrevers peptide control RP

2008 Shi J

Journal ofAutoimmunity, InPress, CorrectedProof, Availableonline 3 June

Prevalence andsignificance ofantibodies tocitrullinated humanpapilloma virus-47

custompeptide

applied biosystems peptidesynthesizer

2008 Hsu L-J

CellularSignalling,Volume 20,Issue 7, July

Zfra is an inhibitorof Bcl-2 expressionand cytochrome crelease from the

custompeptide full length Zfra peptide

2008 Leen A

J. Virol., Jan2008; 82: 546 -554

Identification ofHexon-SpecificCD4 and CD8 T-Cell Epitopes forVaccine and

custompeptide

To identify the minimal epitopesequences, additional shorterpeptides were obtained fromGenemed Synthesis, Inc..

2008 Rennolds J

Mediated by theCOPI Coat inEpithelial CellsJ. Biol. Chem.,Jan 2008; 283:

Cystic FibrosisTransmembraneConductanceRegulatorTrafficking Is

custompeptide SNAP-23

2008 Karagianni P

Mol. Cell. Biol.,Jan 2008; 28:705 - 717

ICBP90, a NovelMethyl K9 H3Binding ProteinLinking ProteinUbiquitination with

custompeptide Biotinylated histone tail peptides

2008 Jang WS

Antimicrob.AgentsChemother., Feb2008; 52: 497 -504.

The P-113Fragment ofHistatin 5 Requiresa Specific PeptideSequence forIntracellularTranslocation inCandida albicans,Which IsIndependent of Cell

custompeptide

The peptides (P-113 and P-113Q2.10) and N-terminal biotin-labeled peptides were synthesizedby using standard solid-phasesynthesis protocols and werepurified by reversed-phase high-performance liquid chromatographyby Genemed Synthesis Inc. (SanFrancis

2008 Callahan MK

PNAS, Feb2008; 105: 1662 - 1667.

Heat-shock protein90 associates withN-terminalextended peptidesand is required for

custompeptide epitope II, SHL8, and 18-mer SHL8

2008 Khan IH

Clin. VaccineImmunol., Mar2008; 15: 433 -438

Profiling Antibodiesto Mycobacteriumtuberculosis byMultiplexMicrobeadSuspension Arrays

custompeptide Ag85B peptides

2008BevelanderGS

J. Endocrinol.,Mar 2008; 196:625 - 635.

CYP27A1expression ingilthead sea bream(Sparus auratus,L.): effects of

custompeptide PTHrP (1-34)

2008Perez-Berna AJ

J. Biol. Chem.,Mar 2008; 283:8089 - 8101

Identification of theMembrane-activeRegions ofHepatitis C Virus p7Protein:BIOPHYSICAL

custompeptide

771FFCAAWYIKGRLAPGAAY788(with NH2-terminal acetylation andCOOH-terminal amidation)

2008 Hill JA

J. Exp. Med., Apr2008; 205: 967 -979

Arthritis induced byposttranslationallymodified(citrullinated)fibrinogen in DR4-

custompeptide

Peptides used in these studies weresynthesized and purified by themanufacturer (Genemed Synthesis).

2008 Luo G

J. Biol. Chem.,Apr 2008; 283:10433 - 10444

The SphingolipidLong-chain Base-Pkh1/2-Ypk1/2Signaling PathwayRegulates

custompeptide Pil1, Lsp1

2008 Kim M-H

J. Biol. Chem.,Apr 2008;doi:10.1074/jbc.M801655200

Protease-activatedreceptor-2increasesexocytosis viamultiple signal

custompeptide

PAR-2 and the reversed peptide(RP, `N'-LRGILS-`C')

2008 Sarangi PP

IL-10 and NaturalRegulatory T Cells:Two IndependentAnti-InflammatoryMechanisms inHerpes SimplexVirus-InducedOcular

custompeptide SSIEFARL peptide

2008 Liu F

FASEB J, May2008;doi:10.1096/fj.07-104539

Overexpression ofDyrk1A contributesto neurofibrillarydegeneration in

custompeptide Dyn-atide 3

2008 Liberman Z

Am J PhysiolEndocrinolMetab, Jun2008; 294:E1169 - E1177

Coordinatedphosphorylation ofinsulin receptorsubstrate-1 byglycogen synthasekinase-3 and

custompeptide IRS-1 peptide

2008Perez-Berna AJ

Interaction of theMostMembranotropicRegion of the HCVE2 EnvelopeGlycoprotein withMembranes.Biophysical

custompeptide peptide E2(fp)

2008 Fenske S

J. Biol. Chem.,Jun 2008;doi:10.1074/jbc.M800029200

Overexpression ofthe PDZ1 domainof PDZK1 blocksthe activity ofhepatic scavengerreceptor, class B,type I (SR-BI) by

custompeptide

30-mer amino-terminal peptide fromthe murine PDZK1 proteinsequence, coupled to keyhole limpethemocyanin (KLH)

2008 Winthrop K

Clin. J. Am. Soc.Nephrol., Jun2008;doi:10.2215/CJN.01010208

Interferon gammaRelease Assays forDiagnosingMycobacteriumtuberculosisInfection in RenalDialysis Patients

custompeptide

Each peptide pool was comprised of15 amino acid peptides, and eachpeptide overlapped by an 11-aminoacid segment with the adjacentpeptide (5 μg/peptide per ml;Genemed Synthesis, South SanFrancisco, CA).

2008SherwoodRK

Eukaryot. Cell,Jun 2008;doi:10.1128/EC.00138-08

The MicrotubuleMotor Protein Kar3is Required forNormal MitoticDivision andMorphogenesis in

custompeptide

Alpha pheromone(GFRLTNFGYFEPG)

2008 Wang G

Antimicrob.AgentsChemother., Jun2008;doi:10.1128/AAC.

Anti-HIV-1 Activityof AntimicrobialPeptides Derivedfrom Human andBovine Cathelicidins

custompeptide

20 synthetic peptides derived fromhuman and bovine cathelicidins

2008 Quintarelli C

Blood, Jun 2008;doi:10.1182/blood-2008-04-150045

Cytotoxic Tlymphocytesdirected to thePreferentiallyExpressed Antigenof Melanoma(PRAME) targetchronic myeloidleukemia

custompeptide

ELAGIGILTV (from MART-1)23,RMFPNAPYL (from Wilms tumor-1,WT-1)12, VLQELNVTV (PR1peptide from PR3 protein)11,KVAELVHFL (from MAGE-A3)24,ILAKFLMWL and RLVDDFLLV(from human telomerase,hTERT)25;26 and YMDGTMSQV(from tyrosinase, Tyr)

2008 Fan T-C

J. Biol. Chem.,Jun 2008;doi:10.1074/jbc.M803516200

Characterization ofmolecularinteractionsbetween eosinophil

custompeptide

RNase1 peptide MTQGRCKPVNK-biotin (R1), and HIV-TAT peptideYGRKKRRQRRRK-biotin (Tat)

2008 Carl Jr. JJ. Immunol; 181:320 - 328.

Autoreactive TCells EscapeClonal Deletion inthe Thymus by a

custompeptide

MOG peptide 35-55(MEVGWYRSPFSRVVHLYRNGK)

2008 Nykamp KRNA, Jul 2008;14: 1378 - 1389.

C. elegans La-related protein,LARP-1, localizesto germline Pbodies and

custompeptide

synthetic keyhole-limpit-hemocyanin(KLH)-conjugated peptides

2008 Kim M-H

J. Biol. Chem.,Jul 2008; 283:18711 - 18720.

Protease-activatedReceptor-2IncreasesExocytosis viaMultiple Signal

custompeptide reversed peptide (RP, N-LRGILS-C)

2008 Valadares N

The Journal ofSteroidBiochemistry andMolecularBiology, Volume

Ligand inducedinteraction ofthyroid hormonereceptor beta withits coregulators

custompeptide

Peptides (>95% pure) werepurchased from Genemed SynthesisInc., San Antonio, USA.

2008PietrokovskiR


New Insights intothe AutoinhibitionMechanism ofGlycogen SynthaseKinase-3β

custompeptide

Peptides, including p9CREB,ILSRRPS(p)YR, pseudosubstratepeptide, and RPRTTS(p)FAES,were synthesized by GenemedSynthesis, Inc. (San Francisco,USA

2008 Linnoila J

Neuron, Volume60, Issue 4, 26November 2008,Pages 625-641

A MammalianHomolog ofDrosophilaTumorous ImaginalDiscs, Tid1,Mediates AgrinSignaling at theNeuromuscularJunction

custompeptide

The Tid1 short-specific polyclonalantibody (anti-Tid1S) wasgenerated by immunizing a rabbitwith the last 20 residues in the Cterminus ofmouse Tid1S(VEGTVNGVTHTSTGKRSTGN)(Genemed Synthesis, SanFrancisco, CA).

2008 Kursula I

Structure,Volume 16,Issue 11, 12November 2008,Pages 1638-1648

Structural Basis forParasite-SpecificFunctions of theDivergent Profilin ofPlasmodiumfalciparum

custompeptide

The peptides PPPPPPPP(octaproline)and KKIPAPPPFLLKK (GenemedSynthesis) were dissolved in thedialysisbuffer.

2008 Zafra R

Journal ofComparativePathology,Volume 139,Issue 4,November 2008,Pages 169-176

A Study of the Liverof GoatsImmunized with aSynthetic Peptideof the Sm14Antigen andChallenged withFasciola hepatica

custompeptide

Each immunizing dosecontained 80 mg of a syntheticpeptide (NEKNSESKLTQ-C of theSm14 antigen with a purityof 99% [Genemed Synthesis Inc.,San Francisco,USA]

2008 Pérez-Berná A

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1778,Issue 10,October 2008,Pages 2069-2080

The pre-transmembraneregion of the HCVE1 envelopeglycoprotein:Interaction withmodel membranes

custompeptide

T h e p e p t i d e E 1P T M c o r res p o n d i n g to t h e s e qu e n c e3 0 9-YPGHVSGHRMAWDMMMNWSPTTALVVSQLLRI-340 rom HCV strain IB4J, with N-terminal acetylation and C-terminalamidation, wasobtained from Genemed Synthesis,San Franc

2008 Ausili A

Journal ofStructuralBiology, Volume164, Issue 1,October 2008,Pages 146-152

The interaction ofthe Bax C-terminaldomain withnegatively chargedlipids modifies thesecondary structureand changes itsway of insertion intomembranes

custompeptide

the synthetic Bax C-terminal domainpeptide(Bax-C) including residues 169–192of Bax (NH3+ -169 TWQTVTIFVAGVLTASLTIWKKMG 192 -COO) was obtained from GenemedSynthesis Inc. (San Antonio, TX,USA)

2008DinamarcaM

Chemico-BiologicalInteractions,Volume 175,Issues 1-3, 25September 2008,Pages 142-149

Release ofacetylcholinesterase (AChE) from β-amyloid plaquesassembliesimproves thespatial memory

custompeptide

A 1–42 peptide corresponding tothe human sequence(Bachem Inc., Torrance, CA., lot no.T-20964amd andGenemed Synthesis Inc., South SanFrancisco, CA)

2008 Lorenzetti F

Neuron, Volume59, Issue 5, 11September 2008,Pages 815-828

MolecularMechanismsUnderlying aCellular Analog ofOperant RewardLearning

custompeptide

e peptide sequenceKKRREILTRRPSYRK with Ser85(underlined) phosphorylated(Genemed Synthesis, SanFrancisco, CA).

2008 Shi J

Journal ofAutoimmunity,Volume 31,Issue 2,September 2008,Pages 131-135

Prevalence andsignificance ofantibodies tocitrullinated humanpapilloma virus-47E2345–362 inrheumatoid arthritis

custompeptide

E2345–362 and citrullinatedE2345–362, in which arginine348wassubstituted with citrulline, weresynthesized, using solid-phasetechniques on an AppliedBiosystems Peptide Synthesizer(Genemed Synthesis, Inc., SanFrancisco, CA, USA)

2008 Misra U

CellularSignalling,Volume 20,Issue 8, August2008, Pages1459-1470

The cAMP-activated GTPexchange factor,Epac1 upregulatesplasma membraneand nuclear Aktkinase activities in8-CPT-2-O-Me-cAMP-stimulatedmacrophages:Gene silencing of

custompeptide

Peptide substrates for Akt1Ser-473kinase, NH2-RRPHFPQFSYSA-COOH, and for Akt1Thr-308 kinase,NH2-KTFCGTPEYLAPEVRR-COOH, were synthesized byGenemed, San Francisco, CA

2008 Ying J

TsinghuaScience &Technology,Volume 13,Issue 4, August2008, Pages 433-

PreliminaryEvaluation of aCandidate Multi-Epitope-VaccineAgainst theClassical Swine

custompeptide

Eleven overlapping peptides (BC1-BC5 and A1-A6)were commercially synthesized byGenemed SynthesisInc. (USA)

2008 Saenger YCancer Res; 68:9884 - 9891

IMMUNOLOGY:Improved TumorImmunity UsingAnti-TyrosinaseRelated Protein-1MonoclonalAntibody Combined

custompeptide

Peptides analyzed, includinggp100/pmel 17 peptide gp10025-33,Tyrp1455-462, and Ova257-264(SIINFEKL), were synthesized byGenemed Synthesis

2008 McGargill MJ. Immunol; 181:7593 - 7605

Drak2 Regulatesthe Survival ofActivated T Cellsand Is Required forOrgan-Specific

custompeptide

A total of 1 106 cells was stimulatedin vitro with 30 mug of MOG35-55peptide (Genemed Synthesis) for 2h.

2008 Wang G

J. Biol. Chem.,Nov 2008; 283:32637 - 32643.

Structures ofHuman HostDefenseCathelicidin LL-37and Its Smallest

custompeptide

To facilitate peptide-lipid NOEobservations, 2 m m synthetic LL-37(>95% purity, Genemed Synthesis,TX)

2008 Spinner D

J. Virol., Nov2008; 82: 10701 - 10708.

Accelerated PrionDiseasePathogenesis inToll-Like Receptor

custompeptide

Amplified products were sequencedby Genemed Synthesis (SanAntonio, TX)

2008 Victorino G

Am J PhysiolHeart CircPhysiol, Nov2008; 295:H2164 - H2171.

Ischemia-reperfusion injury inrats affectshydraulicconductivity in two

custompeptide

Reverse and forward primers wereobtained from Genemed Synthesis(South San Francisco, CA)

2008 Park K

Cancer Res., Oct2008; 68: 8400 -8409.

Insulin-like GrowthFactor–BindingProtein-2 Is aTarget for theImmunomodulation

custompeptide

IGFBP-2 peptides were synthesizedby Genemed Synthesis, Inc.,

2008 Mo CJ. Immunol; 181:5681 - 5690

Stat4 IsoformsDifferentiallyRegulateInflammation andDemyelination inExperimental

custompeptide

The 21-aa peptide(MEVGWYRSPFSRVVHLYRNGK)corresponding to mouse MOGp35-55 was obtained from GenemedSynthesis

2008 Beal A

J. Immunol., Oct2008; 181: 4815 - 4824.

Protein Kinase CRegulates Stabilityof the PeripheralAdhesion RingJunction andContributes to the

custompeptide

PG13 from HIV p24 Gag wassynthesized by Genemed Synthesis

2008 Zhang HJ. Immunol; 181:4638 - 4647.

Intrinsic andInduced Regulationof the Age-Associated Onsetof SpontaneousExperimentalAutoimmune

custompeptide

Peptides PLP139-151(HSLGKWLGHPDKF) and OVA323-339 (ISQAVHAAHAEINEAGR) werepurchased from GenemedSynthesis.

2008 Fan T

J. Biol. Chem.,Sep 2008; 283:25468 - 25474.

Characterization ofMolecularInteractionsbetween EosinophilCationic Proteinand Heparin

custompeptide

RNase1 peptide MTQGRCKPVNK-biotin (R1), and HIV-TAT peptideYGRKKRRQRRRK-biotin (Tat) werepurchased from GenemedSynthesis (South San Francisco,CA).

2008 Quintarelli CBlood, Sep 2008;112: 1876 - 1885.

Cytotoxic Tlymphocytesdirected to thepreferentiallyexpressed antigen

custompeptide

All peptides were obtained fromGenemed Synthesis (San Antonio,TX).

2008 Winthrop K

Clin. J. Am. Soc.Nephrol., Sep2008; 3: 1357 -1363.

Interferon- ReleaseAssays forDiagnosingMycobacteriumtuberculosisInfection in RenalDialysis Patients

custompeptide

Each peptide pool was comprised of15 amino acid peptides, and eachpeptide overlapped by an 11-aminoacid segment with the adjacentpeptide (5 μg/peptide per ml;Genemed Synthesis, South SanFrancisco, CA)

2008 Sallum U

Antimicrob.AgentsChemother., Sep2008; 52: 3006 -3012.

MECHANISMS OFRESISTANCE:InducibleResistance of FishBacterialPathogens to the

custompeptide

mature sequence of cecropin B withgreater than 95 purity and waspurchased from GenemedSynthesis Inc., San Antonio, TX.

2008SherwoodR

Eukaryot. Cell,Sep 2008; 7:1460 - 1474.

Microtubule MotorProtein Kar3 IsRequired forNormal MitoticDivision and

custompeptide

Alpha pheromone(GFRLTNFGYFEPG) wassynthesized by Genemed Synthesis.

2008 Wang G


Anti-HumanImmunodeficiencyVirus Type 1Activities ofAntimicrobialPeptides Derived

custompeptide

Here, we report on the anti-HIVactivities of 20 synthetic peptides (purity; Genemed Synthesis, Inc.)derived from human and bovinecathelicidins.

2008KobayashiM

PNAS, Jul 2008;105: 10090 -10094.

Conserved T cellreceptor -chaininduces insulinautoantibodies

custompeptide

Peptides used for stimulation werehigh-performance liquidchromatography purified (>98%)and dissolved in sterilelipopolysaccharide-free saline at aneutral pH (Genemed SynthesisInc.).

2008 Kim M

J. Biol. Chem.,Jul 2008; 283:18711 - 18720.

Protease-activatedReceptor-2IncreasesExocytosis viaMultiple SignalTransduction

custompeptide

corresponding to the tetheredligand of mouse PAR-2 and thereversed peptide (RP, N-LRGILS-C)were from Genemed Synthesis(South San Francisco, CA).

2008 Carl JJ. Immunol;181:320 - 328

Autoreactive TCells EscapeClonal Deletion inthe Thymus by aCD24-Dependent

custompeptide

MOG peptide 35-55(MEVGWYRSPFSRVVHLYRNGK)was purchased from GenemedSynthesis.

2008 Nykamp KRNA, Jul 2008;14: 1378 - 1389.

C. elegans La-related protein,LARP-1, localizesto germline Pbodies and

custompeptide

rats were injected with synthetickeyhole-limpit-hemocyanin (KLH)-conjugated peptides (GenemedSynthesis, Inc.)

2008 Liberman Z

Am J PhysiolEndocrinolMetab, Jun2008; 294:E1169 - E1177.

Coordinatedphosphorylation ofinsulin receptorsubstrate-1 byglycogen synthasekinase-3 and

custompeptide

Synthetic IRS-1 peptide, based onthe IRS-1 sequenceRREGGMS332RPAS336VDG, wassynthesized by Genemed Synthesis(San Francisco, CA)

2008 Liu F

FASEB J, Sep2008; 22: 3224 -3233.

Overexpression ofDyrk1A contributesto neurofibrillarydegeneration in

custompeptide

Dynatide 3 was synthesized byGenemed Synthesis, Inc. (SouthSan Francisco, CA, USA).

2008 Sarangi P

J. Immunol., May2008; 180: 6297 - 6306.

IL-10 and NaturalRegulatory T Cells:Two IndependentAnti-InflammatoryMechanisms inHerpes Simplex

custompeptide

Cells were left untreated orstimulated with SSIEFARL peptide(HSVgB498-505; synthesized atGenemed Synthesis)

2008 Hill J

J. Exp. Med., Apr2008; 205: 967 -979.

Arthritis induced byposttranslationallymodified(citrullinated)fibrinogen in DR4-

custompeptide

Peptides used in these studieswere synthesized and purified by themanufacturer (Genemed Synthesis).

2008Pérez-Berná A

J. Biol. Chem.,Mar 2008; 283:8089 - 8101.

Identification of theMembrane-activeRegions ofHepatitis C Virus p7Protein:BIOPHYSICALCHARACTERIZATI

custompeptide

.the sequence 771FFCAAWYIKGRLAPGAAY 788(with NH 2 -terminal acetylation andCOOH-terminal amidation) wasobtained from Genemed Synthesis,San Francisco, CA

2008 Han E

Anticancer Res,Mar 2008; 28:957 - 963.

Characterization ofAkt Overexpressionin MiaPaCa-2 Cells:Prohibitin Is an AktSubstrate both InVitro and in Cells

custompeptide

Synthetic peptides (prohibitinsequence from 247 to 269) weregenerated by Genemed Synthesis(San Francisco, CA, USA).

2008 Khan I

Clin. VaccineImmunol., Mar2008; 15: 433 -438.

Profiling Antibodiesto Mycobacteriumtuberculosis byMultiplexMicrobeadSuspension Arrays

custompeptide

Peptides representing Ag85Bprotein were obtained fromGenemed Synthesis Inc. (SanAntonio, TX).

2008BevelanderG

J. Endocrinol.,Mar 2008; 196:625 - 635.

CYP27A1expression ingilthead sea bream(Sparus auratus,L.): effects of

custompeptide

Pufferfish (Takifugu rubripes)PTHrP (1-34) was synthesized byGenemed Synthesis Inc. (SanFrancisco, CA, USA).

2008 Emami N

J. Biol. Chem.,Feb 2008; 283:3031 - 3041.

Human Kallikrein-related Peptidase14 (KLK14) Is aNew ActivatorComponent of theKLK ProteolyticCascade:

custompeptide

The synthetic heptapeptides werepurchased from GenemedSynthesis (San Francisco, CA).

2008 Jang W

Antimicrob.AgentsChemother., Feb2008; 52: 497 -504.

The P-113Fragment ofHistatin 5 Requiresa Specific PeptideSequence forIntracellularTranslocation inCandida albicans,Which IsIndependent of CellWall Binding

custompeptide

The peptides (P-113 and P-113Q2.10) and N-terminalbiotinlabeledpeptides were synthesized by usingstandard solid-phase synthesisprotocolsand were purified by reversed-phasehigh-performance liquidchromatographyby Genemed Synthesis Inc. (SanFrancisc

2008 Karagianni P

Mol. Cell. Biol.,Jan 2008; 28:705 - 717.

ICBP90, a NovelMethyl K9 H3Binding ProteinLinking ProteinUbiquitination with

custompeptide

Biotinylated histone tail peptideswere synthesized and purified byGenemed Synthesis Inc.

2008 Rennolds J

J. Biol. Chem.,Jan 2008; 283:833 - 839.

Cystic FibrosisTransmembraneConductanceRegulatorTrafficking Is

custompeptide

1/2,000 for SNAP-23 produced forus by Genemed Synthesis

2008 Leen A

J. Virol., Jan2008; 82: 546 -554.

Identification ofHexon-SpecificCD4 and CD8 T-Cell Epitopes for

custompeptide

shorter peptides were obtained fromGenemed Synthesis, Inc. (SouthSan Francisco, CA)

2008 Sun JN

MolecularMicrobiology(2008) 70(5),1246–1260

Uptake of theantifungal cationicpeptide Histatin 5 byCandida albicansSsa2p requiresbinding to non-conventionalsites within theATPase domain

custompeptide

Hst 5, inhibitor peptides (EEVD,EPSNDGPTVEEVD) withinthe C-terminus ‘anchor region’ andpeptides Ssa2127-157,Ssa2329-356, Ssa268-83 andSsa2245-257 covering Hst 5 bindingregions identified by peptide arraysfor competition assayswere synthesized by G

2008 Gujraty KV

Inc. J Polym SciPart A: PolymChem 46:7249–7257, 2008

Synthesis ofHomopolymers andCopolymersContainingan Active Ester ofAcrylic Acid byRAFT: Scaffolds for

custompeptide

Peptide, Ac-HTSTYWWLDGAPKAm,was purchased from GenemedSynthesis(San Antonio, TX).

2008 Schreiner BEur. J. Immunol;38: 2706–2717

PD-1 ligandsexpressed onmyeloid-derivedAPC in theCNS regulate T-cellresponses in EAE

custompeptide

PLP139-151 (HSLGKWLGHPDKF),OVA323-339(ISQAVHAAHAEINEAGR)and MOG35-55(MEVGWYRSPFSRVVHLYRNGK)were synthesized by GenemedSynthesis.

2008 Hsu CC

Journal ofThrombosis andHaemostasis, 6:1578–1585

A snake venommetalloproteinase,kistomin, cleavesplateletglycoprotein VI andimpairs plateletfunctions

custompeptide

Kistomin cleavage sites on GPVIwere analyzed as describedpreviously [8]. In brief, high-performance liquid chromatography(HPLC)-purified synthetic peptidescorresponding tomembrane-proximal extracellularsequences of GPVI(Leu180-Glu209, Glu202-Thr221

2008 StokelyJ. Neurosci Res;86: 2111–2124

Transient 5-(4-Phenylbutoxy)Psoralen(PAP-1) TreatmentDissociatesDevelopingPathologies inAutoimmune OpticNeuritis

custompeptide

Tandem 50-ll injectionscontaining a total of 200 lg MOGpeptide 35–55 (mouse/ratsequence, custom synthesis byGenemed Synthesis Inc., SouthSan Francisco, CA)

2008 Zou P

FEMS ImmunolMed Microbiol53; 79–84

Fine-epitopemapping ofan antibody thatbinds theectodomain ofin£uenzamatrixprotein 2

custompeptide

M2e peptide which contained the 23aminoacid residues of M2e (aa2–24, K-SLLTEVETPIRNEWGCRCNDSSD)was synthesized at GenemedSynthesis(San Francisco, CA).

2008 Zhang F

Rapid Commun.Mass Spec; 22:1455–1460

Quantitation ofmethylatedhemoglobinadducts in asignature peptidefrom rat blood byliquidchromatography/negative electrosprayionization

custompeptide

Methylated rat hemoglobin betachain signature peptidesMeVHLTDAEK (MW 926) andMeVHLTDAEK (MW 933),where L (bold font) is L-leucine-d3and A is L-alanline-d4,were synthesized by GenemedSynthesis Inc. (South SanFrancisco, CA, USA).

2008 Fu CL

Clin ExpImmunol; 153(2):258–268

Induction of IL-10producing CD4+ Tcells with regulatoryactivities bystimulation with IL-10 gene-modifiedbone marrow

custompeptide

The OVA 323–339 peptide wassynthesized and purified byhighperformanceliquid chromatography (GeneMed,South SanFrancisco, CA).

2008SchuenckRP

FEMS ImmunolMed Microbiol52; 431–435

Multiplex PCRassay toidentifymethicillin-resistantStaphylococcushaemolyticus dna

The oligonucleotideprimers were purchased fromGenemed SynthesisInc. (San Francisco, CA). Theprimers designed in this studySH1 (50-GGT CGC TTA GTC GGAACA AT-30) and SH2(50-CAC GAG CAA TCT CAT CACCT-30) were used todetect a 271-bp fragment of mvaA

2008UCHIYAMAT

J. Cell. Physiol.214: 645–654

FunctionalCharacterizationand Cloning ofAmino AcidTransporter B0,R(ATB0,R) dna

Plasmids were extracted andsequenced by infrared fluorescentdye labeled M13 primers (GeneMedSynthesis, South SanFrancisco, CA).

2008 Vavaiya KV

Journal ofNeuroscienceResearch86:694–701

Effects of CaudalHindbrain LactateInfusion on Insulin-InducedHypoglycemiaand NeuronalSubstrateTransporterGlucokinase andSulfonylureaReceptor-1Gene Expression inthe OvariectomizedFemale Rat Dorsal dna

PCR primers were designed inBeacon Designersoftware (Table I) and obtained fromGenemed Synthesis (SanFrancisco, CA).

2008 Guillén J


Membraneinsertion of thethree mainmembranotropicsequences from misc

2008 Yuan L

EuropeanJournal ofPharmaceuticsandBiopharmaceutics, Volume 70,

Reversiblelipidization ofsomatostatinanalogues for theliver targeting misc

2008 Briski K

Neuropeptides,Volume 42,Issues 5-6,October-December 2008,Pages 585-591

Effects oforchidectomy onadaptation ofarcuateneuropeptide Y,proopiomelanocortin, and cocaine- andamphetamine-related transcript misc

2008 Lass A

ExperimentalCell Research,Volume 314,Issue 14, 15August 2008,Pages 2715-2723

Analysis of Npl4deletion mutants inmammalian cellsunravels new Ufd1-interacting motifsand suggests a misc

2008 Hsu L

CellularSignalling,Volume 20,Issue 7, July

Zfra is an inhibitorof Bcl-2 expressionand cytochrome crelease from the misc

2008 Witting P.K.

ThrombosisResearch, InPress, CorrectedProof, Available

Polymorphonuclearleukocytephagocytic functionincreases in miscl

2008 Myoung J

J. Virol., Jun2008; 82: 5606 -5617

AnticapsidImmunity Level, NotViral PersistenceLevel, Correlateswith theProgression ofTheiler's Virus- miscl

All peptides were purchased fromGeneMed Synthesis Inc. and wereused as previously described

2008 Song YC

Eur. J. Immunol.2008. 38:3178–3190

Arginines in theCDR of anti-dsDNAautoantibodiesfacilitate cellinternalization viaelectrostatic Miscl

In addition, Jurkatcells or human T cells were co-treated with Arg10 (50 or 150 mg/mL) (Genemed Synthesis, SanAntonio, TX, USA)

2008 Ma, YD

Chinese Journalof Chemistry, 26,1019—1022

Binary Assembly ofAu Nanoparticleswith ControllableTwo-dimensionalArchitectureDirected byPhosphate Miscl

DNAreagents were purchased fromGeneMed Synthesis

2008 patel LN

JOURNAL OFPHARMACEUTICAL SCIENCES,VOL. 97, NO. 6;2340-2349

Molecular andFunctionalExpression ofMultidrugResistance-Associated Protein-1 in Primary Miscl

The resultant plasmidswere sequenced using infraredfluorescent dyelabeledM13 primers (Genemed Synthesis,SouthSan Francisco, CA).

2009 Penuela S

Mol. Biol. Cell,Oct 2009; 20:4313 - 4323.

GlycosylationRegulatesPannexinIntermixing andCellular Localization


generate site-directed rabbitpolyclonal antibodies by GenemedSynthesis (San Antonio, TX).Specific peptides (Table 1) weresynthesized...affinity purified againstthe corresponding peptides byGenemed Synthesis (Table 1)

2009 Tufail M

Insect MolecularBiology (2009)18(3), 281–294

Molecular cloning,characterization,expression patternand cellulardistribution of anovarian lipophorinreceptorin the cockroach,Leucophaeamaderae


Rabbit anti-LemLpR antibody wasgenerated against a 20-aminoacidresidue peptide (GenemedSynthesis, Inc., San Antonio, TX,USA). The peptide used was:GHASLLFARRHDIRKISLDHandwas from the EGF-precursorhomology domain (aa position:437–456) of LemLpR (ac

2009HalversonGR

TRANSFUSION2009;49:485-494

Murine monoclonalanti-s and otheranti-glycophorin Bantibodies resultingfrom immunizationswith a GPB.speptide


Balb/c mice were immunized with aKLH-conjugated20-mer peptide corresponding to theGPB.s sequenceTKSYISSQTNGETGQLVHRF(Genemed Synthesis, Inc.,San Francisco, CA).

2009 Gustin JL

The PlantJournal (2009)57, 1116–1127

MTP1-dependentZn sequestrationinto shoot vacuolessuggests dual rolesin Zn tolerance andaccumulation


TgMTP1antibody was prepared by GenemedSynthesis, Inc.

2009Cunningham D

MolecularGenetics andMetabolism,Volume 98,Issue 4,December 2009,Pages 356-366

Developmentalexpression patternof thecholesterogenicenzyme NSDHLand negativeselection of NSDHL-deficient cells in theheterozygous


A rabbit polyclonal antiserum wasgenerated using the peptideantigen DEAVERTVQSFHHLRKDKcorresponding to amino acidresidues 345–362 of mouse NSDHL(Genemed Synthesis, SanFrancisco, CA)

2009 Van Laar V

Neurobiology ofDisease, Volume34, Issue 3, June2009, Pages 487-500

Proteomicidentification ofdopamine-conjugated proteinsfrom isolated ratbrain mitochondriaand SH-SY5Y cells


. The MtCK and mitofilin polyclonalantibodies used in this study weregenerated for our laboratory byGenemed Synthesis, Inc. (SanAntonio, TX).

2009 Sun Y

Cell, Volume137, Issue 1, 3April 2009,Pages 123-132

Separase IsRecruited to MitoticChromosomes toDissolve SisterChromatidCohesion in a DNA-Dependent Manner


A polyclonal antibody to theC terminus of SCC1(CEPYSDIIATPGPRFH) wascustom produced by GenemedSynthesis (CA) and affinity-purified.

2009 Lin W

Biochemical andBiophysicalResearchCommunications, Volume 379,Issue 4, 20February 2009,Pages 1066-1071

The N-terminus ofporcine circovirustype 2 replicationprotein is requiredfor nuclearlocalization and oribinding activities


Two oligonucleotides,CAGCGCACTTCGGCAGCGGCAGand GTCGCGTGAAGCCGTCGCCGTC, representing thepositive and negative sense of thePCV2 ori sequence that ishomologous to the minimal bindingsite(MBS) of PCV1 ori, weresynthesized by Genemed Synthesis,Inc

2009 Branham M

J. Biol. Chem.,Sep 2009; 284:24825 - 24839.

MECHANISMS OFSIGNALTRANSDUCTION:Epac Activates theSmall G ProteinsRap1 and Rab3A to


The rabbit polyclonal antibodiesagainst Epac were generated byGenemed Synthesis, Inc.

2009VasudevanS

Mol. CancerTher., Aug 2009;8: 2478 - 2489.

RESEARCHARTICLES:Neuroblastoma-derived secretoryprotein is a novel


anti-NDSP antibodies (anti-NDSP-Ab1 and -Ab2, generated byGenemed Synthesis, Inc.);

2009 White E

Mol. Endocrinol.,Jul 2009; 23:1115 - 1123.

ORIGINALRESEARCH:Pharmacochaperone-Mediated Rescueof Calcium-SensingReceptor Loss-of-Function Mutants


.the presence of CaSR wasdetected with anti-CaSR polyclonalantibody (LRG, 1:2000, or ADD,1:1000; custom-generated byGenemed Synthesis, Inc., SanAntonio, TX)

2009 Stanisic V

J. Biol. Chem.,Jun 2009; 284:16135 - 16145.

PROTEINSYNTHESIS,POST-TRANSLATIONALMODIFICATION,ANDDEGRADATION:OTU Domain-containing UbiquitinAldehyde-binding


Antibody against human OTUB1was custom produced and assayedby Genemed Synthesis, Inc.

2009 Kang Q

J. Cell Sci., Apr2009; 122: 1091 - 1099.

RESEARCHARTICLES:A Golgi-associatedprotein 4.1B variantis required for


Antibodies All anti-4.1 antibodieswere raised in rabbits at GenemedSynthesis.

2009SchowalterR

J. Virol., Feb2009; 83: 1511 -1522.

VIRUS-CELLINTERACTIONS:Low-pH Triggeringof HumanMetapneumovirusFusion: Essential


Antipeptide antibodies (GenemedSynthesis, San Francisco, CA) weregenerated using amino acids 524 to538 of HMPV F. Viruses

2009 Wright A

PLANT CELL,Jan 2009; 21:234 - 247.

RESEARCHARTICLES:discordia1 andalternativediscordia1 FunctionRedundantly at theCortical DivisionSite to Promote


used to generate two rabbitpolyclonal antibodies (GenemedSynthesis).

2009 Morales J

The AmericanJournal ofHumanGenetics,Volume 85,Issue 5, 13November 2009,

HomozygousMutations inADAMTS10 andADAMTS17 CauseLenticular Myopia,Ectopia Lentis,Glaucoma,

CustomDNA

First-strand cDNA libraries frommultiple human adult and fetaltissues were obtained commercially(Genemed Synthesis, SouthSan Francisco, CA

2009 Kuo

Journal ofControlledRelease, Volume139, Issue 3, 3November 2009,Pages 197-204

Interactionsbetweenoctaarginine and U-937 humanmacrophages:Global geneexpression

CustomDNA

The octaarginine (RRRRRRRR; R8)and fluorescein-labeled octaarginineused in this study were purchasedfrom Genemed Synthesis, Inc.(San Antonio, TX, USA).

2009 LaSala D

AnalyticalBiochemistry,Volume 394,Issue 1, 1November 2009,Pages 56-61

Coexpression ofCYP11B2 orCYP11B1 withadrenodoxin andadrenodoxinreductase forassessing the

CustomDNA

Human adrenal gland GETRare full-length cDNA was obtainedfrom Genemed Synthesis (SanFrancisco, CA).

2009 Zhou Y

Biosensors andBioelectronics,Volume 24,Issue 11, 15 July2009, Pages

Potentiometricmonitoring DNAhybridization

CustomDNA

The oligonucleotides werepurchased from Genemed SynthesisInc

2009 Ahram D

The AmericanJournal ofHumanGenetics,Volume 84,Issue 2, 13February 2009,Pages 274-278

A HomozygousMutation inADAMTSL4Causes Autosomal-Recessive IsolatedEctopia Lentis

CustomDNA

To determine the expression patternof ADAMTSL4, firststrand cDNAlibraries from an adult and fetalmultipletissue human panel wereobtained commercially(Genemed Biotechnologies, Inc;South San Francisco,CA).

2009 Briski K

Neuroscience,Volume 164,Issue 3, 15December 2009,Pages 1152-1160

In situcoexpression ofglucose andmonocarboxylatetransporter mRNAsin metabolic-sensitive caudaldorsal vagalcomplexcatecholaminergic

custompeptide

Forward and reverse primers fortarget genes were designedwith Beacon Designer 5 software(Premier Biosoft Intl., Palo Alto,CA, USA), and obtained fromGenemed Synthesis, Inc. (SanFrancisco, CA, USA)

2009 Pérez-Berná A

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1788,Issue 10,October 2009,Pages 2183-2193

Biophysicalcharacterization ofthe fusogenicregion of HCVenvelopeglycoprotein E1

custompeptide

The peptide E1FP corresponding tothe sequence274 AMYVGDLCGSIFLVSQLFT291 from HCV strain 1B4J (with N-terminal acetylation and Cterminalamidation) was obtained fromGenemed Synthesis, SanAntonio, Texas

2009 Zafra R

Research inVeterinaryScience, Volume87, Issue 2,October 2009,Pages 226-232

Study of the localimmune responseto Fasciolahepatica in the liverand hepatic lymphnodes of goatsimmunised with apeptide of the

custompeptide

Immunizationwas carried out in three doses (80 lgeach) of a synthetic peptide:N-EKNSESKLTQ-C of the Sm14antigen with a purity of 99%(Genemed Synthesis Inc, SanFrancisco, USA

2009 Melo M

Journal ofMolecularBiology, Volume392, Issue 3, 25September 2009,Pages 736-746

Interaction of theDengue VirusFusion Peptide withMembranesAssessed by NMR:The Essential Role

custompeptide

The peptides were purchased fromGenemed Synthesis, Inc.(South San Francisco, CA, USA).

2009 Mora-Pale M

Bioorganic &MedicinalChemistry,Volume 17,Issue 14, 15 July2009, Pages5146-5152

Inhibition of humanvascular NADPHoxidase byapocynin derivedoligophenols

custompeptide

A proline-rich p22phoxpeptide N-151PPSNPPPRPPAEARK165-C,which was biotinalyted at the N-terminus and amidated at theCterminus was obtained fromGenemed Synthesis Inc. (South SanFrancisco, CA). T

2009 Pusateri C

Archives of OralBiology, Volume54, Issue 6, June2009, Pages 588-594

Sensitivity ofCandida albicansbiofilm cells grownon denture acrylicto antifungalproteins andchlorhexidine

custompeptide

precoating Lucitone disks witheither of the following: (1) 0.12%chlorhexidine gluconate (PerioGard,Colgate-Palmolive, NewYork, NY); (2) 50 mM Hst 5(synthesized by GeneMed Synthesis,Inc., San Antonio, TX);

2009 Bradford S

Journal ofInorganicBiochemistry,Volume 103,Issue 6, June

Copper·Lys-Gly-His-Lys mediatedcleavage oftRNAPhe: Studiesof reaction

custompeptide

ATCUN motifs werepurchased from Bachem (CA), orfrom Genemed Synthesis Inc.(South San Francisco, CA)

2009 Xu J

Journal ofVirologicalMethods,Volume 158,Issues 1-2, June2009, Pages 70-

A model for testingthe immunogenicityof simianimmunodeficiencyvirus andsimian–human

custompeptide

All other peptideswere synthesized by GenemedSynthesis, Inc. (South Francisco,CA)

2009 Kim K

DevelopmentalCell, Volume 16,Issue 5, 19 May2009, Pages 723-733

Antagonismbetween GLD-2Binding PartnersControls GameteSex

custompeptide

To generate a-RNP-8 polyclonalantibodies (CocalicoBiologicals),rats and rabbitswere injected with a Keyhole-limpet-hemocyanin-conjugated peptide(GenemedSynthesis)

2009 Suazo M


Overexpression ofamyloid precursorprotein increasescopper content inHEK293 cells

custompeptide

Human CuBRD (APP135–155)synthetic peptides were fromGenemed Biotechnologies, Inc.(San Francisco, CA)

2009Escobar-Alvarez S

Journal ofMolecularBiology, Volume387, Issue 5, 17April 2009,

Structure andActivity of HumanMitochondrialPeptideDeformylase, a

custompeptide

All peptide substrates werepurchased from GenemedSynthesis (Genemed Synthesis,San Antonio TX). A

2009 Bernard C

FEBS Letters,Volume 583,Issue 7, 2 April2009, Pages1084-1089

Interaction betweenthe C-terminaldomains of N and Pproteins of measlesvirus investigated

custompeptide

the synthetic peptideDSRRSADALLRLQAMAGISEE(Genemed Synthesis, Inc.)

2009 Raymond J

Cryobiology,Volume 58,Issue 2, April2009, Pages 151-156

Ice-binding proteinsfrom enoki andshiitake mushrooms

custompeptide

(STAFTDAAGRSDPDFLE), wasaffinity purified by GeneMed (SouthSanFrancisco, CA).

2009 Chang M

Journal ofEndodontics,Volume 35,Issue 4, April2009, Pages 508-512

Prostaglandin F2α-Induced Interleukin-8 Production inHuman Dental PulpCells Is AssociatedWith MEK/ERK

custompeptide

SpecificPCR primers for b-actin (BAC) andIL-8 were synthesized by GenemedBiotechnologies,Inc (San Francisco, CA).

2009 Hao G

Journal of theAmericanSociety for MassSpectrometry,Volume 20,Issue 4, April2009, Pages 723-727

Neutral Loss ofIsocyanic Acid inPeptide CIDSpectra: A NovelDiagnostic Markerfor MassSpectrometricIdentification ofProtein Citrullination

custompeptide

Citrullinated reference peptidesstandard, including NH2-AA{Cit}AA-COOH, NH2-AARAA-COOH, histone H4peptide (residues 15–26) NH2-AK{Cit}H{Cit}KVL{Cit}DNIcysteine-COOH, and human NPM peptide(residues195–202) NH2-SIRDTPAK-COOH weresynthesized byGen

2009 Posnett D

Vaccine, Volume27, Issue 7, 11February 2009,Pages 1093-1100

Development ofeffective vaccinesfor old mice in atumor model

custompeptide

Peptides were synthesized andpurified by HPLC to >80%purity by GeneMed Synthesis, Inc.(San Francisco, CA).

2009 Teixeira P

BiophysicalJournal, Volume96, Issue 3, 4February 2009,Pages 951-963

PredictionsSuggesting aParticipation of β-Sheet Configurationin the M2 Domainof the P2X7Receptor: A Novel

custompeptide

The peptide sequence wasFGIRFDILVFGTGGKFDIIQLVVY(ADSEG, residues 313–336). TheADSEG peptide was synthesized byGenemed Synthesis (SanFrancisco, CA).

2009 Hoppe M

The Journal ofNutritionalBiochemistry,Volume 20,Issue 1, January2009, Pages 11-16

Hepcidin,interleukin-6 andhematological ironmarkers in malesbefore and afterheart surgery

custompeptide

. Humanhepcidin peptide(DTNFPICLFCCKCCKNSSCGLCCIT)was synthesized with an additionalcysteine residue at theC terminus for conjugation tokeyhole limpet hemocyanin(Genemed Synthesis, SanFrancisco, CA, USA).

2009 Hsu KMol. Biol. Cell;20: 5127 - 5137.

MBP-1 SuppressesGrowth andMetastasis ofGastric CancerCells through COX-2

custompeptide

the synthetic peptideGCPLPSAKLVPLRRG (amino acidresidues 16-30 of MBP-1) wasprocessed to immunize rabbits byGenemed Synthesis.

2009 Pao-Chun L

J. Biol. Chem.,Dec 2009; 284:34954 - 34963.

MECHANISMS OFSIGNALTRANSDUCTION:Cytoplasmic ACK1Interaction withMultiple ReceptorTyrosine Kinases IsMediated by Grb2:

custompeptide

Tyr 703 residues of the Axlactivation loop was synthesized: Ac-CKIYNGDpYpYRQGR (where pYrepresents phosphotyrosine;Genemed Synthesis, Inc.)

2009 Keren IRNA, Dec 2009;15: 2299 - 2311.

AtnMat2, a nuclear-encoded maturaserequired for splicingof group-II intronsin Arabidopsismitochondria

custompeptide

The purified protein was dialyzedagainst buffer containing 20 mMTris-HCl at pH 6.8, and injected intorabbits for the production ofpolyclonal antisera (GenemedSynthesis Inc.).

2009 Hofacre A

J. Virol., Dec2009; 83: 12483 - 12498.

GENOMEREPLICATIONANDREGULATION OFVIRAL GENEEXPRESSION:Jaagsiekte SheepRetrovirus Encodes

custompeptide

The anti-CA hybridoma wasgenerated by a commercial source(Genemed Synthesis, Inc.) usingbacterially expressed JSRV CAprotein.

2009 Hama-Tomioka K

Anesth. Analg.,Dec 2009; 109:1935 - 1942.

NEUROSURGICALANESTHESIOLOGY ANDNEUROSCIENCE:The Role of 20-Hydroxyeicosatetraenoic Acid inCerebral ArteriolarConstriction and

custompeptide

gp91ds-tat and sgp91ds-tat weresynthesized by Genemed Synthesis(San Antonio, TX)

2009 Kota J

ScienceTranslationalMedicine, Nov2009; 1: 6ra15.

RESEARCHARTICLES:Follistatin GeneDelivery EnhancesMuscle Growth and

custompeptide

prepared for the AAV1 capsid (104peptides) and human follistatin (48peptides; Genemed Synthesis).

2009 Hong B

Cancer Res., Oct2009; 69: 8076 -8084.

Human Suppressorof CytokineSignaling 1ControlsImmunostimulatory

custompeptide

E2 protein peptide (RLWHYPCTI)were synthesized and purified byhigh-performance liquidchromatography to purity byGenemed Synthesis, Inc.

2009 Passarella r

Clin. CancerRes., Oct 2009;15: 6421 - 6429.

IMAGING,DIAGNOSIS,PROGNOSIS:RecombinantPeptides asBiomarkers for

custompeptide

Biotinylated-KKGGGEGEVGLGsynthetic peptide was purchasedfrom Genemed Synthesis, Inc.

2009 McKee

J. Immunol., Oct2009; 183: 4403 - 4414.

CELLULARIMMUNOLOGYAND IMMUNEREGULATION:Alum InducesInnate ImmuneResponses throughMacrophage andMast Cell Sensors,

custompeptide

a cysteine linked 3K peptide(FEAQKAKANKAVDGGGC)purchased from GenemedSynthesis.

2009 Oswald-Richter K

Infect. Immun.,Sep 2009; 77:3740 - 3748.

HOST RESPONSEANDINFLAMMATION:Cellular Responsesto MycobacterialAntigens ArePresent inBronchoalveolar

custompeptide

Each peptide was synthesized bysolid-phase Fmoc (9-fluorenylmethoxy carbonyl)chemistry (Genemed Synthesis,San Diego, CA)

2009

Antimicrob.AgentsChemother., Sep 2009;53: 3705 -3714.


MECHANISMS OFACTION:Lipid SegregationExplains SelectiveToxicity of a Seriesof Fragments

custompeptide

The peptides with C-terminalamidation were synthesized andpurified to by Genemed Synthesis,Inc. (San Antonio, TX).

2009 Burgoyne A

Cancer Res.,Sep 2009; 69:6960 - 6968.

EXPERIMENTALTHERAPEUTICS,MOLECULARTARGETS, ANDCHEMICALBIOLOGY:ProteolyticCleavage of ProteinTyrosine

custompeptide

Peptides synthesized by GenemedSynthesis

2009 Liu Y

Hum. Mol.Genet., Jul 2009;18: 2622 - 2631.

Deletions andmissensemutations ofEPM2A exacerbateunfolded proteinresponse andapoptosis of

custompeptide

and laforin (produced by GenemedSynthesis, Inc., San Francisco, CA,USA)

2009 Jin WBlood; 113: 6603- 6610

Regulation of Th17cell differentiationand EAE inductionby MAP3K NIK

custompeptide

myelin oligodendrocyte glycoprotein(MOG) was purchased fromGenemed Synthesis Inc. (SanFrancisco, CA, 95% purity).

2009 Clayton E

J. Neurosci., Jun2009; 29: 7706 -7717.

CELLULAR/MOLECULAR:The Phospho-DependentDynamin–SyndapinInteraction Triggers

custompeptide


2009 Hsu L

J. Biol. Chem.,Jun 2009; 284:16049 - 16059.

MECHANISMS OFSIGNALTRANSDUCTION:TransformingGrowth Factor β1Signaling viaInteraction with Cell

custompeptide

a synthetic peptide of murine Hyal-2, NH 2 -CPDVEVARNDQLAWL-COOH (amino acids 227-241) wasmade (Genemed Synthesis)

2009 Farías G

J. Biol. Chem.,Jun 2009; 284:15857 - 15866.

MECHANISMS OFSIGNALTRANSDUCTION:Wnt-5a/JNKSignaling Promotesthe Clustering of

custompeptide

Reagents Formylated hexapeptidewas obtained from GenemedSynthesis, Inc. (South SanFrancisco, CA)

2009 Loftus J

Mol. CancerTher., Jun 2009;8: 1505 - 1514.

RESEARCHARTICLES:The Pyk2 FERMdomain as a targetto inhibit glioma

custompeptide

The MTS peptide(KGEGAAVLLPVLLAAPG) wasobtained from Genemed Synthesis.

2009 Binder RJ. Immunol; 182:6844 - 6850

CD40-IndependentEngagement ofMammalian hsp70by Antigen-Presenting Cells

custompeptide

AH1-19(RVTYHSPSYVYHQFERRAK) andOVA-20(SGLEQLESIINFEKLTEWTS) withthe presented epitope underlinedand were synthesized at GenemedSynthesis.

2009

Hirschhorn-CymermanD

J. Exp. Med.,May 2009; 206:1103 - 1116.

OX40 engagementand chemotherapycombinationprovides potentantitumor immunitywith concomitant

custompeptide

Peptides were synthesized byGenemed Synthesis, Inc.

2009 Jou M

J. Nutr., May2009; 139: 835 -841.

BIOCHEMICAL,MOLECULAR,AND GENETICMECHANISMS:Tissue-SpecificAlterations in ZincTransporterExpression inIntestine and Liver

custompeptide

fragments for Zip1(FLVLVMEQITLAYKEQSGPSPLEETRALLGTVNGGPQHWHDGGVPQASGAPATPSAP) and Zip4(CAEETPELLNPETRRL) weresynthesized by Genemed Synthesis

2009 Duan F

Cancer Res., Apr2009; 69: 3545 -3553.

IMMUNOLOGY:Immune Rejectionof Mouse TumorsExpressing Mutated

custompeptide


2009 Faghiri Z

FASEB J, Aug2009; 23: 2780 -2789.

RESEARCHCOMMUNICATIONS:The role oftegumentalaquaporin from thehuman parasiticworm, Schistosoma

custompeptide

NH2-KSDFVVDVDYDDSHRDG-COOH, comprising a sequence atthe carboxyl terminus of SmAQPcorresponding to aa 279-295, wassynthesized by Genemed Synthesis,Inc. (San Antonio, TX, USA).

2009 Ding W

J. Biol. Chem.,Mar 2009; 284:6809 - 6817.

DNA:REPLICATION,REPAIR,RECOMBINATION,ANDCHROMOSOMEDYNAMICS:Inhibition of

custompeptide

...grasckkcsesipkdkvphwyhfscfwkv)derived from the first zinc finger ofhuman PARP-1 (apoPARPzf) wascommercially synthesized byGenemed Synthesis Inc., (SanAntonio TX).

2009 Louis CBlood, Mar 2009;113: 2442 - 2450.

IMMUNOBIOLOGY:Enhancing the invivo expansion ofadoptivelytransferred EBV-specific CTL withlymphodepleting

custompeptide

The following peptides (GenemedSynthesis, San Francisco, CA),

2009 Mruk D

Biol Reprod, Mar2009; 80: 590 -601.

TESTIS:RAB13 Participatesin EctoplasmicSpecializationDynamics in theRat Testis

custompeptide

This peptide, which shared nosignificant homologies with anyprotein except RAB13 whencompared to the existing proteindatabase at GenBank, was purifiedby HPLC, microsequenced,conjugated to keyhole limpethemocyanin, and used forimmunization of two f

2009 Hayashi TPNAS; 106: 2764- 2769

Prevention ofautoimmunedisease byinduction oftolerance to Toll-

custompeptide

Mice were immunized with 125 g ofmyelin oligodendrocyte glycoprotein(MOG) 35-55 (Genemed Synthesis)

2009 Hou W

J. Exp. Med.,Feb 2009; 206:313 - 328.

Th17 cells enhanceviral persistenceand inhibit T cellcytotoxicity in amodel of chronic

custompeptide

All peptides were synthesized byGeneMed Synthesis Inc

2009 Chen YPNAS, Jan 2009;106: 761 - 766.

BIOCHEMISTRY:PTMap—Asequencealignment softwarefor unrestricted,accurate, and full-spectrum

custompeptide

Synthetic peptides weresynthesized by GL Biochem andGenemed Synthesis.

2009 Bailey JJ. Virol., Jan2009; 83: 88 - 97.

PATHOGENESISAND IMMUNITY:Evidence of CD8+T-Cell-MediatedSelective Pressureon HumanImmunodeficiencyVirus Type 1 nef in

custompeptide

peptides were synthesized either atthe Johns Hopkins oncology peptidesynthesis facility or at GenemedSynthesis Inc. (San Antonio, TX)

2009 Cohen AM

Rapid Commun.Mass Spectrom.2009; 23:1049–1060

Quantification ofGreenland halibutserum vitellogenin:a trip from the deepsea to the massspectrometer

custompeptide

The synthetic signature peptidestandard (sequence:FFGQEIAFANIDK, purity >95%) andits isotopic homologue used asinternal standard (sequence:FFGQEIAFANIDK , purity >95%,where K is the lysineresiduelabeled with 13C6 and 15N2) werepurchased fromGene

2009 Dejean ASNat Immunol;10(5): 504–513

Foxo3 controls themagnitude of T cellimmune responsesbymodulatingdendritic cellfunction

custompeptide

At the indicated time points, spleenswere harvested from LCMV infectedor uninfected control mice andsplenocytes werestimulated with gp33 or gp61peptide (Genemed Synthesis)

2009 Guo S

GeneTherapy;16:1300-1313

Induction ofprotective cytotoxicT-cell responses bya B-cell-basedcellular vaccinerequires stable

custompeptide

OVA-1 (OVA257–264, SIINFEKL)and OVA-2 (OVA323–339,ISQAVHAAHAEINEAGR) peptideswere synthesized by GenemedSynthesis

2009 Kwon W

Cancer Letters,Volume 277,Issue 2, 18 May2009, Pages 155-163

G-T haplotype(2677G > T/A and3435C > T) ofABCB1 genepolymorphisms isassociated withethnic differences misc

2009 Liew C

FEBS Letters,Volume 583,Issue 1, 5January 2009,Pages 49-54

Interaction of thehumansomatostatinreceptor 3 with themultiple PDZdomain proteinMUPP1 enables misc

2009 Mangano K

Clinical & ExpImmunol; 159:159–168

Variable effects ofcyclophosphamidein rodent models ofexperimentalallergicencephalomyelitisce Miscl

PLP (139–151) was synthesizedby Genemed Synthesis (SanFrancisco, CA, USA).

2009 Ma Y

Chem. Eur. J,15, 13135 –13140

PolyACHTUNGTRENUNG(l-lysine)-InducedAggregation ofSingle-Strand Oligo-DNA-ModifiedGold Nanoparticles Miscl

TheDNA reagent was purchasedfrom Genemed Synthesis, the DNAsequence was 5 -CGCATTCAGGAT-3 , and anonbridging oxygen atom ofthe second phosphate group fromthe 5’-terminus in the backbone wassubstituted by a sulfur atom toensure the affinity of the o

2009 Ahlem C

Cont. Challengesin Autoimm;1173: 781–790

HE3286: A NovelSynthetic Steroidas an OralTreatment forAutoimmune Miscl

Proteolipidprotein 139–151 (PLP, GenemedSynthesis,San Francisco, CA)

2010 Fouda M

Journal of InsectPhysiology,Volume 56,Issue 12,December 2010,Pages 1728-1737

Precursor structure,distribution andpossible functionsof pigment-dispersing hormone(PDH) in the


2010 Say E

Molecular Cell,Volume 38,Issue 2, 23 April2010, Pages 236-249

A FunctionalRequirement forPAK1 Binding tothe KH(2) Domainof the Fragile XProtein-RelatedFXR1


Active PAK1 can phosphorylateFXR1 at Ser420; antibodies to thissite show increased phosphorylationwhen fragile X proteins are recruitedto stress granules

2010 KONG W

J. Cell. Physiol.223: 151–157,2010

Cyclophilin C-AssociatedProtein/Mac-2Binding ProteinColocalizes WithCalnexin andRegulates theExpression ofTissueTransglutaminase


The anti-CyCAP polyclonal antibodywas produced at GenemedSynthesis, Inc. (South SanFrancisco, CA). The peptide,SYKYRQFYTYNYGSQ, from the ratCyCAP hypothetical proteinsequence (GenBank AccessionAF065438) was synthesized andinjected into rabbits for

2010 Rinkevich Y

DevelopmentalBiology, Volume345, Issue 1, 1September 2010,Pages 94-104

Piwi positive cellsthat line thevasculatureepithelium, underliewhole body


Rabbit anti Bl-Piwi antibody wasproduced by Genemed SynthesisInc. (http://www.genemedsyn.com).

2010 Cmejla R

Biochemical andBiophysicalResearchCommunications, Volume 395,Issue 2, 30 April2010, Pages 163-

Human MRCKα isregulated bycellular iron levelsand interferes withtransferrin ironuptake


e. For the detection of MRCKa, acustom-made affinity purifiedrabbit antibody (GenemedSynthesis, TX, USA) was used at adilution of 1:200 in PBS with 5% low-fat milk,

2010Stepanchick A

Biochemical andBiophysicalResearchCommunications, Volume 395,Issue 1, 23 April

The cargo receptorp24A facilitatescalcium sensingreceptor maturationand stabilization inthe early secretory


probed with anti-CaSR polyclonalantibodies(LRG, 1:2000, Genemed Synthesis,Inc.)

2010 Ellis N

The Journal ofInfectiousDisease, Oct2010; 202: 1059 - 1067.

BACTERIA:Priming theImmune System forHeart Disease: APerspective onGroup A


were synthesized as 25mers with an11-amino acid overlap by theMolecular Biology Resource Centerat OUHSC and by GenemedSynthesis, Inc

2010 Siddiqi S

J. Lipid Res., Jul2010; 51: 1918 -1928.

A novel multiproteincomplex is requiredto generate theprechylomicrontransport vesiclefrom intestinal ER


Polyclonal antibodies against ratVAMP7 were raised in rabbitscommercially (Genemed Synthesis,San Francisco, CA) using asynthetic 19-mer peptidecorresponding to amino acids 105-123 of rat VAMP7.

2010CavanaughA

J. Biol. Chem.,Jun 2010; 285:19854 - 19864.

CELL BIOLOGY:Calcium-sensingReceptorBiosynthesisIncludes aCotranslationalConformational


CaSR was detected on the upperportion with rabbit polyclonal anti-LRG antibody (1:2000; custom-generated by Genemed Synthesis,Inc. against LRG epitope residues374-391),

2010 Eckert R

J. Biol. Chem.,Apr 2010; 285:10736 - 10747.

NEUROBIOLOGY:Discovery of aNovel InsectNeuropeptideSignaling SystemClosely Related tothe Insect


polyclonal ACP rabbit antibody wasobtained commercially fromGeneMed Synthesis.

2010DenekampN

Biol Reprod, Apr2010; 82: 714 -724.

EMBRYO:LateEmbryogenesisAbundant (LEA)Proteins inNondesiccated,


Preparation of Polyclonal AntiseraTwo polyclonal antisera wereprepared by Genemed Synthesis,Inc.,

2010Cunningham D

Hum. Mol.Genet., Jan2010; 19: 364 -373.

Significantcontributions of theextraembryonicmembranes andmaternal genotypeto the placentalpathology in


Immunologic studies Polyclonalrabbit antisera were raisedcommercially (Genemed Synthesis,San Francisco, CA, USA)

2010Barriga-Montoya C

ComparativeBiochemistry andPhysiology - PartA: Molecular &IntegrativePhysiology,Volume 157,Issue 4,

Effect of pigmentdispersing hormoneon the electricalactivity of crayfishvisualphotoreceptorsduring the 24-hcycle

custompeptide

PDH solution was obtained bydissolving the hormone (sequenceNSELINSILGLPKVMNEA,purchased from GenemedSynthesis, Inc.) inVH solution at a 1-nM concentration

2010 Rahman A

AnalyticaChimica Acta,Volume 681,Issues 1-2, 29November 2010,Pages 49-55

Absolutequantificationmethod andvalidation ofairborne snow craballergentropomyosin usingtandem massspectrometry

custompeptide

Standard signature peptide,SQLVENELDHAQEQLSAATHK(purity > 95.3%;molar mass = 2348.53 Da) and itsdeuterated isotopic homologusing d3-l-alanine- (purity > 97.1%;molar mass = 2357.53 Da) werepurchased from GeneMedSynthesis (San Francisco, CA, USA).

2010 Macedo B

EuropeanJournal ofMedicinalChemistry,Volume 45,Issue 11,November 2010,Pages 5468-5473

Synthesis and anti-prion activityevaluation ofaminoquinolineanalogues

custompeptide

The Syrian hamster prion proteinpeptide (109e149) was acquiredfrom Genemed Synthesis, Inc. (SanAntonio, TX, USA), where it wasmade using solid phase synthesisand purified by RP-HPLC (>90%purity)


Journal ofNeuroimmunology, Volume 227,Issues 1-2, 8October 2010,Pages 153-161

Antibodies againstthe voltage-dependent anionchannel (VDAC)and its protectiveligand hexokinase-Iin children withautism

custompeptide

The 21-amino acid peptides,KVNNSSLIGLGYTQTLKP GIKC(Lys235–Lys255) of VDAC1 (P1) andMIAAQLLAYYFTELKDDQVKKC(Met1–Lys21) of hexokinase-I (P2), wereobtained from Genemed Synthesis,Inc. (San Francisco, CA).

2010 De Genst E

Journal ofMolecularBiology, Volume402, Issue 2, 17September 2010,Pages 326-343

Structure andProperties of aComplex of α-Synuclein and aSingle-DomainCamelid Antibody

custompeptide

Titrations of full-length14N α-synuclein and a 14N 12-residuepeptide, N-SEEGYQDYEPEA-C(Genemed Synthesis Inc., NewYork, USA), were carried out with15N-labeled NbSyn2 at 0.3 mM in20 mM phosphate buffer, pH 7.4, at298 and 283 K.

2010 Jin Y

Journal ofNeuroimmunology, Volume 226,Issues 1-2, 14September 2010,

Type I interferonsignals controlTheiler's virusinfection site,cellular infiltration

custompeptide

All synthetic peptides werepurchased from GenemedSynthesis (San Francisco, CA). S

2010 Liao Y

The InternationalJournal ofBiochemistry &Cell Biology,Volume 42,Issue 8, August2010, Pages1363-1369

miR-584 mediatespost-transcriptionalexpression oflactoferrin receptorin Caco-2 cells andin mouse smallintestine during theperinatal period

custompeptide

Anti-serum was produced in rabbitsagainst a chemically synthesizedpeptide, CTVGDRWSSQQGSKAD,which corresponds to partof the deduced LfR amino acidsequence (Genemed Synthesis Inc.).

2010 Cao Y

TsinghuaScience &Technology,Volume 15,Issue 4, August2010, Pages 447-451

Characterization ofAntibodyResponses Againstthe 2F5 EpitopeELDKWA sing HIV-1 Env-MediatedMembrane Fusionand NeutralizationAssays

custompeptide

. The ELDKWA epitope bearingpeptide P1 (CELDKWAG-ELDKWA) and the C-domainpeptide P2 (CELD-KWASLWNWFNIT) werecommercially synthesizedby Genemed Synthesis Inc(California, USA).

2010 Bergamin E

Molecular Cell,Volume 39,Issue 1, 9 July2010, Pages 100-109

The CytoplasmicAdaptor ProteinDok7 Activates theReceptor TyrosineKinase MuSK viaDimerization

custompeptide

A 13-residue phosphopeptiderepresenting the regionencompassing MuSKTyr553, Ac-LDRLHPNPMpYQRM,was synthesized (GenemedSynthesis)and solubilized in 100 mM Tri-HCl(pH 8.0) and 150 mM NaCl.

2010 Luo W

ProteinExpression andPurification,Volume 72,Issue 1, July

Kinetic andstructuralcharacterization ofhuman mortalin

custompeptide

The fluorescein-labeled peptide,LSLPPVKLHK-fluorescein wassynthesized by Genemed Synthesis,Inc.

2010 Li C

Cancer Letters,Volume 292,Issue 2, 28 June2010, Pages 246-253

Tobaccocarcinogen NNKtransporter MRP2regulates CFTRfunction in lungepithelia:Implications forlung cancer

custompeptide

We also generated our own anti-MRP2 antibody (rabbit-2825, against the last 12 aminoacids of MRP2, i.e., a.a.1534–1545) (Genemed Synthesis,CA), which was affinitypurified usingProtein-A column.

2010 Epand R

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1798,Issue 6, June2010, Pages1272-1280

Lipid clustering bythree homologousarginine-richantimicrobialpeptides isinsensitive to aminoacid arrangementand induced

custompeptide

. The peptide KR-12 wassynthesized and purified toN95% by Genemed Synthesis, Inc.(San Antonio, TX)

2010 Black S

Neuroscience,Volume 167,Issue 3, 19 May2010, Pages 765-773

Rapid, transienteffects of theprotein kinase Cactivator phorbol 12-myristate 13-acetate on activityand trafficking ofthe rat high-affinitycholine transporter

custompeptide

. Polyclonal CHT antibody wasraised in rabbits against a peptideencoding 16 residues conserved atthe carboxyl-terminus of humanand rat CHT[DVDSSPEGSGTEDNLQ](Genemed Synthesis,San Antonio, TX, USA)

2010 Zhang L

InternationalJournal ofRadiationOncology*Biology*Physics,Volume 77,Issue 1, 1 May2010, Pages 261-

Mitigation Effect ofan FGF-2 Peptideon AcuteGastrointestinalSyndrome AfterHigh-Dose IonizingRadiation

custompeptide

s. FGF-P was synthesized bystandard, solid-phase methods(Genemed Synthesis,San Antonio, TX) at a level of 97%purity, as determined by reverse-phase high-performance liquidchromatography (HPLC).

2010 Oblander S

Molecular andCellularNeuroscience,Volume 44,Issue 1, May2010, Pages 78-93

Distinct PTPmu-associatedsignaling moleculesdifferentiallyregulate neuriteoutgrowth on E-, N-, and R-cadherin

custompeptide

. In brief, the IQGAP1 peptidecorresponds to aminoacids 1054–1077 of IQGAP1 plusthe N-terminal TAT sequence(GRKKRRQRRRMVVSFNRGARGQNALRQILAPVVK), which wasoriginally developed by Dr. DavidSacks (Mataraza et al., 2003) andsynthesized by Genemed Synth

2010 Karnabi E

Journal ofAutoimmunity,Volume 34,Issue 2, March2010, Pages 80-86

Congenital heartblock: Identificationof autoantibodybinding site on theextracellular loop(domain I, S5–S6)

custompeptide

. The sequence ofall fusion proteins were verified bycommercial sequencing (GenemedSynthesis, San Antonio, TX, USA).

2010 Hoang P

Metabolism,Volume 59,Issue 3, March2010, Pages 343-349

The neurosurvivalfactor Humanininhibits β-cellapoptosis via signaltransducer andactivator oftranscription 3

custompeptide

Humanin peptide was synthesizedby GenemedSynthesis Biotechnologies (SouthSan Francisco, CA).

2010 Wang G

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1798,Issue 2,February 2010,Pages 114-121

Structure, dynamicsand mapping ofmembrane-bindingresidues of micelle-bound antimicrobialpeptides by naturalabundance 13CNMR spectroscopy

custompeptide

GF-17, KR-12 and its single-residuepeptide mutants, RI-10, aurein1.2, and LLAA (Table 1) with C-terminal amidation (N95% pure)weresynthesized and purified byGenemed Synthesis (San Antonio,TX)

2010 Thon J

J. Cell Biol., Nov2010; 191: 861 -874.

Cytoskeletalmechanics ofproplateletmaturation andplatelet release

custompeptide

probed with a rabbit polyclonalantibody against the C-terminalsequence of mouse β1-tubulin(LEDSEEDAEEAEVEAEDKDH;Genemed Synthesis, Inc.).

2010 Deshmukh L

J. Biol. Chem.,Nov 2010; 285:34875 - 34884.

SIGNALTRANSDUCTION:Integrin β3PhosphorylationDictates ItsComplex with the

custompeptide

corresponding to mono- and bi-phosphorylated 3 CT, MPN 3 , MPC3 , and BP 3 Peptide ( Fig. 1B),were chemically synthesized(Genemed Synthesis, Inc

2010 Bachar R

Cardiovasc Res,Nov 2010; 88:360 - 366.

Humanin isexpressed inhuman vascularwalls and has acytoprotectiveeffect againstoxidized LDL-

custompeptide

scrambled HN peptide weresynthesized by Peptide International(Louisville, KY, USA) or GenemedSynthesis Biotechnologies (SouthSan Francisco, CA, USA)

2010 Alby K

Eukaryot. Cell,Nov 2010; 9:1690 - 1701.

Identification of aCell Death Pathwayin Candida albicansduring theResponse toPheromone

custompeptide

. SCD medium refers to syntheticcomplete medium supplementedwith 2% glucose.pheromone MF13(GFRLTNFGYFEPG) wassynthesized by Genemed Synthesis

2010 Botten J

J. Virol., Oct2010; 84: 9947 -9956.

VACCINES ANDANTIVIRALAGENTS:A MultivalentVaccinationStrategy for thePrevention of Old

custompeptide

Peptides ( pure) were obtainedfrom Genemed Synthesis, Inc.(South San Francisco, CA).

2010 Grotzke J

J. Immunol., Oct2010; 185: 4336 - 4343.

HOST DEFENSE:SecretedImmunodominantMycobacteriumtuberculosisAntigens Are

custompeptide

Bacteria, virus, andcells...AEMKTDAATLAQEAGNFERI) was synthesized, purified to 90%purity (Genemed Synthesis)

2010 Martin AJ. Immunol; 185:3326 - 3336

Ethylenecarbodiimide-TreatedSplenocytesCarrying Male CD4Epitopes ConferHistocompatabilityY ChromosomeAntigen Transplant

custompeptide

Peptides (Dby,NAGFNSNRANSSRSS; Uty,WMHHNMDLI; Smcy,KCSRNRQYL; OVA323-339,ISQAVHAAHAEINEAGR) wereobtained from Genemed Synthesis(San Antonio, TX).

2010Al-HashimiA

J. Biol. Chem.,Sep 2010; 285:28912 - 28923.

MOLECULARBASES OFDISEASE:Binding of Anti-GRP78Autoantibodies toCell SurfaceGRP78 IncreasesTissue Factor

custompeptide

Both chemicals were diluted to afinal concentration of 5-10 m in 1�TBS. The CNVKSDKSC peptide(GeneMed Synthesis, San Antonio,TX)

2010 Tseng C

J. Biol. Chem.,Sep 2010; 285:27641 - 27651.

PROTEINSTRUCTURE ANDFOLDING:Asparagine of z8Insert Is Critical forthe Affinity,Conformation, and

custompeptide

Synthetic oligonucleotide primersand synthetic z8 peptide weresynthesized by Integrated DNATechnology (Coralville, IA) andGenemed Synthesis (SanFrancisco, CA),

2010Shanmugarajan S

Endocrinology,Sep 2010; 151:4389 - 4399.

GROWTHFACTORS-CYTOKINES:OsteoclastInhibitory Peptide-1Binding to the

custompeptide

OIP-1/hSca c-peptide(NFSAADGGLRASVTLLGAGLLLSLLPALLRFGP) was synthesized byGenemed Synthesis, Inc. (SanFrancisco, CA)

2010 Foster W

Am J PhysiolLung Cell MolPhysiol, Sep2010; 299: L345 - L352.

MARCKS-relatedpeptide modulatesin vivo the secretionof airway Muc5ac

custompeptide

given by intranasal aspiration 50mul of 100 muM myristoylatedamino-terminal sequence peptide(MANS; Genemed Synthesis, SanFrancisco, CA)

2010 Castillo J

J. Biol. Chem.,Aug 2010; 285:26269 - 26278.

DEVELOPMENTALBIOLOGY:Calcineurin-mediatedDephosphorylationof SynaptotagminVI Is Necessary for

custompeptide

phosphorylated synaptotagmin VI(antiPStg) was raised againstRRLKKKKTTIKKNTL,phosphorylated in the second T, byGenemed Synthesis (SanFrancisco, CA).

2010 O'Connell K

J. Virol., Jul2010; 84: 7018 -7028.

PATHOGENESISAND IMMUNITY:Control of HIV-1 inElite Suppressorsdespite OngoingReplication andEvolution in Plasma

custompeptide

The peptides were synthesized atGenemed Synthesis Inc. (SanAntonio, TX).

2010 Sun W

J. Biol. Chem.,Jul 2010; 285:21341 - 21348.

SIGNALTRANSDUCTION:ProteinPhosphatase 2AActs as a Mitogen-activated ProteinKinase KinaseKinase 3 (MEKK3)Phosphatase to

custompeptide

human MEKK3 (pThr-516/pSer-520)were produced by immunizingrabbits with MEKK3 phosphopeptide(GASKRLQpTICMpSGTGMR) atGenemed Synthesis, Inc.

2010 Fuentes J

Am J PhysiolRegulatoryIntegrative CompPhysiol, Jul2010; 299: R150- R158.

Parathyroidhormone-relatedprotein-stanniocalcinantagonism inregulation ofbicarbonate

custompeptide

The PTHrP(1-34) (2) from pufferfish was synthesized by GenemedSynthesis (San Francisco, CA).

2010 Cuitino L

J. Neurosci., Jun2010; 30: 8411 -8420.

CELLULAR/MOLECULAR:Wnt-5a ModulatesRecycling ofFunctional GABAAReceptors onHippocampal

custompeptide

Foxy-5 was obtained from GenemedSynthesis; Lithium, BDNF, 3,3-tetramethylbenzidine (TMB),Immuno...Foxy-5) derived from thesequence of the Wnt-5a ligand(Genemed Synthesis).

2010 Zhang HJ. Immunol; 184:6629 - 6636

TGF-β–InducedMyelin Peptide-Specific RegulatoryT Cells MediateAntigen-SpecificSuppression ofInduction ofExperimental

custompeptide

PLP178-191 (NTWTTCQSIAFPSK),MOG35-55(MEVGWYRSPFSRVVHLYRNGK),and OVA323-339(ISQAVHAAHAEINEAGR) werepurchased from GenemedSynthesis (San Francisco, CA).

2010 Perdomo G

J. Lipid Res., Jun2010; 51: 1298 -1311.

RESEARCHARTICLES:A role ofapolipoprotein D intriglyceridemetabolism

custompeptide

mmunizing rabbits with the peptideVKKYLGRWYEIEKIP(corresponding to amino acidresidue 18-32 of apoD protein,Genemed Synthesis, SanFrancisco, CA)

2010 Gottwein J

J. Virol., May2010; 84: 5277 -5293.

PATHOGENESISAND IMMUNITY:Novel InfectiouscDNA Clones ofHepatitis C VirusGenotype 3a(Strain S52) and 4a(Strain ED43):

custompeptide

.peptides spanning the entirepolyprotein of HCV genotype 4a(strain ED43; GenBank accessionnumber Y11604) were purchasedfrom Genemed Synthesis.

2010 MEASE P

J Rheumatol,Apr 2010; 37:692 - 703.

Safety, Tolerability,and ClinicalOutcomes afterIntraarticularInjection of aRecombinantAdeno-associatedVector Containing a

custompeptide

exposure to 4 synthetic peptidepools (Genemed Synthesis Inc.,San Antonio, TX, USA)

2010 Niland BJ. Immunol; 184:4025 - 4032

CLINICALIMMUNOLOGY:Cleavage ofTransaldolase byGranzyme BCauses the Loss ofEnzymatic Activity

custompeptide

Synthetic TALpep was producedand purified to 99% homogeneity byGenemed (Genemed Synthesis,San Francisco, CA)

2010 Kang H

J. Virol., Mar2010; 84: 2774 -2786.

PATHOGENESISAND IMMUNITY:Predominant ClonalAccumulation ofCD8+ T Cells withModerate Avidity inthe CentralNervous Systems

custompeptide

All synthetic peptides purified byhigh-performance liquidchromatography to purity wereobtained from Genemed Synthesis,San Francisco, CA.

2010 Yang J

J. Cell Sci., Mar2010; 123: 861 -870.

RESEARCHARTICLES:GSK-3β promotescell survival bymodulating Bif-1-

custompeptide

L803-mts [N-myristol-GKEAPPAPPQS(P)P] wassynthesized by Genemed Synthesis(San Antonio, TX)

2010 Sun W

J. Biol. Chem.,Mar 2010; 285:7911 - 7918.

SIGNALTRANSDUCTION:Phosphorylation ofThr-516 and Ser-520 in the KinaseActivation Loop ofMEKK3 Is RequiredforLysophosphatidic

custompeptide

immunizing rabbits with MEKK3phosphopeptide(GASKRLQpTICMpSGTGMR) atGenemed Synthesis, Inc.

2010RadziewiczH

J. Immunol., Mar2010; 184: 2410 - 2422.

CELLULARIMMUNOLOGYAND IMMUNEREGULATION:Transient CD86Expression onHepatitis C Virus-

custompeptide

CMV NLV peptide (NLVPMVATV; 1mug/ml) was used (GenemedSynthesis, San Antonio, TX).

2010 Heslop HBlood, Feb 2010;115: 925 - 935.

PLENARYPAPERS:Long-term outcomeof EBV-specific T-cell infusions toprevent or treatEBV-related

custompeptide

EBV peptides (Genemed Synthesis)were used in enzyme-linkedimmunosorbent spot (EliSpot)assays to determine the frequencyof epitope specific T cells

2010 Lee Y

J. Biol. Chem.,Jan 2010; 285:1726 - 1732.

MOLECULARBASIS OF CELLANDDEVELOPMENTALBIOLOGY:Interaction ofInsulin-like GrowthFactor-binding

custompeptide

The peptides used for dot blotsincluded: Humanin (HN, a knownbinding partner of IGFBP-3 (23);obtained from GeneMed SynthesisInc., San Antonio, TX),

2010 Lue Y


REPRODUCTION-DEVELOPMENT:Opposing Roles ofInsulin-Like GrowthFactor BindingProtein 3 andHumanin in the

custompeptide

GnRH-A injection on d 1 and dailyintratesticular injection of 50 μg HN(Genemed Synthesis, Inc., SanAntonio, TX)

2010 Vockel M

ExperimentalDermatology, 19,888–894

Somatostatinregulates tightjunction functionand composition inhumankeratinocytes

custompeptide

For peptide pulldowns, syntheticpeptides corresponding tothe C-terminus of human SSTR3(KSSTMRISYL) as well asa control peptide (guanylatekinase–associated proteinGKAP; sequence: IYIPEAQTRL)were obtained from GenemedSynthesis (San Antonio, TX, USA)

2010SchaubertKL

Eur. J. Immunol.2010. 40:1950–1962

Generation ofrobust CD81 T-cellresponses againstsubdominantepitopes inconserved regionsof HIV-1by repertoire miningwith mimotopes

custompeptide

TV9 (TLNAWVKVV) and agonistpeptides p30 (TINAWIKVV),TV9p6 (KINAWIKVV), p29(TINAWIKGV) and p5 (KINAWIKGV)peptides were purchased at 4 90%purity from GenemedSynthesis (San Francisco, CA, USA).

2010 Fuller MJ

HEPATOLOGY,Vol. 51, No. 2,2010

Selection-DrivenImmune Escape IsNot a SignificantFactor in theFailure of CD4 TCell Responses inPersistent HepatitisC Virus Infection

custompeptide

Cells were stimulatedwith either the NS31376 wild-type(WT)(YGKAIPLEVI) peptide or with oneof the following mutatedpeptides at various concentrationsas indicated foreach experiment: NS31376 M1(YGKAIPLAAI), NS31376M2 (YGKAIPLAVI), or NS31376 M3(YG

2010 Turnis MEJ. Immunol; 185:4223 - 4232

IRAK-M RemovalCounteractsDendritic CellVaccine Deficits inMigration andLongevity

custompeptide

H2-Kb–restricted OT-I (SIINFEKL)and I-Ad–restricted OT-II(ISQAVHAAHAEINEAGR)(20) peptides were synthesized andpurified byHPLC to .95% purity by GenemedSynthesis (San Antonio, TX).

2010 Getts MTVirology;402:102-111

A critical role forvirus-specific CD8+CTLs in protectionfrom Theiler's virus-induceddemyelination indisease-susceptibleSJL mice

custompeptide

All synthetic peptides were obtainedfrom Genemed Synthesis, SanFrancisco, CA. These includedTMEV peptides VP2121–130(FHAGSLLVFM),VP2165–173(TGYRYDSRT),VP3159–166(FNFTAPFI),VP3173–181(QTSYTSPTI),VP111–20 (SNDDASVDFV),VP3110–120 (NFLFVFTGAAM), and

2010 Briski KP

Journal ofNeuroendocrinology 22, 599–607

Effects ofHypoglycaemia onNeurotransmitterand HormoneReceptorGene Expression inLaser-DissectedArcuateNeuropeptideY⁄Agouti-Related dna

ll. Forward and reverse primers fortarget genes (Table 2) weredesignedwith Beacon Designer 5 software(Premier Biosoft Intl., Palo Alto, CA,USA),and obtained from GenemedSynthesis, Inc. (San Francisco, CA,USA).

2010 Chang M

Biomaterials,Volume 31,Issue 32,November 2010,Pages 8164-8171

The role of reactiveoxygen species andhemeoxygenase-1expression in thecytotoxicity, cellcycle alteration andapoptosis of dental misc

2010 Lee H

InternationalJournal ofBiologicalMacromolecules,Volume 47,

Cleavage of theretinal pigmentepithelium-specificprotein RPE65under oxidative misc

2010 Donia M

Scandinavian J.of Immunol; 72,396–407

Specific and Strain-IndependentEffects ofDexamethasone inthe Prevention andTreatmentof ExperimentalAutoimmuneEncephalomyelitisin Rodents Miscl

EAE: PLP-induced EAE in SJL micePLP(139–151) was synthesized byGenemed Synthesis (SanFrancisco, CA, USA), and EAE wasinduced as previouslydescribed by ourselves and others;Mice wereimmunized by subcutaneousinjections into the left flankof 0.2 ml

2010Kanakasabai S

Immunol, 130,572–588

Peroxisomeproliferator-activated receptor dagonists inhibit Thelper type 1 (Th1)and Th17responses inexperimentalallergicencephalomyelitis Miscl

The 21-amino acid peptide(MEVGWYRSPFSRVVHLYRNGK)corresponding to mouse MOGp35-55 (96 81%pure) was obtained from GenemedSynthesis Inc. (San Francisco,CA).

2010 Jang WS

MolecularMicrobiology(2010) 77(2),354–370

Salivary histatin 5internalization bytranslocation,but notendocytosis, isrequired forfungicidal activity Miscl

Hst 5, biotin-labelled Hst 5 (BHst 5)and FITClabelledHst 5 (F-Hst 5) were synthesized byGenemedSynthesis. (San Francisco, CA).

2010 song YC

ARTHRITIS &RHEUMATISMVol. 62, No. 8, pp2401–2411

ReversingInterleukin-2Inhibition MediatedbyAnti–Double-Stranded DNAAutoantibodyAmeliorates Miscl

In the penetration competitionexperiments, Jurkatcells were cotreated for 48 hourswith or without mAb 9D7(100 g/ml) plus deca-arginine(Arg10; 0, 10, 25, 50, or 100g/ml) (Genemed Synthesis),

2011HerschhornA

J. Immunol., Dec2010; 185: 7623 - 7632.

Antibodies andLentiviruses ThatSpecificallyRecognize a T CellEpitope Derivedfrom HIV-1 Nef CAD

Nef1 and gp120 were synthesizedby M. Fridkin (Weizmann Institute ofScience, Rehovot, Israel), Conpepby Genemed Synthesis (SanAntonio, TX),…

2011 Tatiana V K

J. Virol., Nov2011; 85: 11855 - 11870.

ExpressionStrategy ofDensonucleosisVirus from theGermanCockroach,Blattella germanica


Rabbit polyclonal antibodies weregenerated by Genemed Synthesis(SanAntonio, TX) against the followingoligopeptides, corresponding tovirus ORFs:ORF1,CTFDRPYFYGKPQRVLNSVEL;ORF2, HYSEAKSDIDIQRADTEAIG; ORF3,CNDPLEFHSGPEVGDIPARPR;ORF4, CRVLELTDAVKDE

2011 Zhou Y

J. Virol., Nov2011; 85: 11821 - 11832.

Histone H3Interacts andColocalizes with theNuclear ShuttleProtein and theMovement Proteinof a Geminivirus


The anti-BDMV NSP polyclonalantibodywas raised against an oligopeptide(N -CLRNKRGSSFSQRRFY-C )correspondingto a portion of the N terminus,whereas the MP antibody was raisedagainst an oligopeptide (N -CINSNCKAYQPKSLQ-C )corresponding to a portiono

2011 Bhardwaj R

Infect. Immun.,Oct 2011; 79:4276 - 4284

TegumentalPhosphodiesteraseSmNPP-5 Is aVirulence Factor forSchistosomes


antibody production. NH2-TLKNKGAHGYDPDYK-COOH, apeptide comprising SmNPP-5 aminoacid residues 354 to 369, wassynthesized by Genemed Synthesis,Inc., San Antonio, TX. A cysteineresidue was added at the aminoterminus to facilitate conjugation ofthe pe

2011 Shi Q

Development,Oct 2011; 138:4219 - 4231

The Hedgehog-inducedSmoothenedconformationalswitch assembles asignaling complexthat activatesFused by promotingits dimerization andphosphorylation


Phospho-Fu antibodies weregenerated by Genemed Synthesis(San Antonio, TX) with the followingphospho-peptides asantigens:CDFGLARNMT(p)LGT(p)HVL (forpT151/pT154) andHVLT(p)S(p)IKGTPLYMAPE (forpT158/pS159). Phospho-antibodieswere purified by positiv

2011HumpriesJA

PLANT CELL,Jun 2011; 23:2273 - 2284

ROP GTPases Actwith the Receptor-Like Protein PAN1to PolarizeAsymmetric CellDivision in Maize


A peptide corresponding to aminoacids 124 to 138 of maize ROP2(DDKQFFVDHPGAVPI) wassynthesized, conjugated to KLH,and usedfor polyclonal antibody production inrabbits by Genemed Synthesis

2011 Liu RY

Learn. Mem.,Mar 2011; 18:245 - 249

Serotonin- andtraining-induceddynamic regulationof CREB2 in Aplysia


The anti-CREB2 antibody wasraised by a commercial vendor(Genemed Synthesis, Inc.) againstthe unphosphorylated version of aCREB2 hybrid peptide(SPPDSPEQGPSSPET)constructed to juxtapose thesequences... …

2011 Rawal S

Toxicology andAppliedPharmacology254 (2011)349–354

Metabolism ofaflatoxin B1 inTurkey livermicrosomes: Therelative roles ofcytochromes P4501A5 and 3A37


Rabbit polyclonal anti-P450 1A5(Yip and Coulombe, 2006) and 3A37(Rawal et al., 2010b) sera wereraised against the peptidesequences“FLDFNKRFMKLLKTAVEE (aminoacids 260–277)” and“SQKSDSDGKNSHKA (amino acids278–291),”respectively by Genemed Synthesis

2011Yan-ShenShan

MOLECULARCARCINOGENESIS 50:739–750(2011)

Establishment of anOrthotopicTransplantableGastric CancerAnimal Model forStudying theImmunologicalEffects of NewCancerTherapeuticModules


MUC2-specific antiserum wasobtained by inoculatingrabbits with mouse MUC2 peptideCVRTRRSSPRFLGRK (c-terminalposition 911–924).The antiserum was purified byaffinity chromatographyusing the c-terminal MUC2 peptide.Peptidesused in this study were sy

2011 Misra UK

Journal ofCellularBiochemistry112:1685–1695(2011)

Loss of CellSurface TFII-IPromotesApoptosis inProstateCancer CellsStimulated WithActivated a2-Macroglobulin


Antibodies against MTJ1 wereraised in rabbits against thesequencebeginning at residue 105, NH2-LVAIYEVLKVDERRQRYVDVLCOOH,of MTJ1 (Swiss-Prot primaryaccession no. Q61712)(Genemed Synthesis, San Antonio,TX)

2011 Airavaara M

J. Biol. Chem;286: 45093 -45102

Identification ofNovel GDNFIsoforms and cis-AntisenseGDNFOS Geneand TheirRegulation inHuman MiddleTemporal Gyrus ofAlzheimer Disease


An affinity-purified anti-GDNFOS3antibody was developed by injectingrabbit with epitopepeptide (CKGMSHGQHFTHT)located at the C terminus(Genemed Synthesis, Inc., SanAntonio, TX) and was used forWestern blot of HEK293 and SH-SY5Y, CHO cell lines, and

2011Malovannaya A

Cell, Volume145, Issue 5, 27May 2011,Pages 787-799

Analysis of theHumanEndogenousCoregulator


anti-GFP (custom, GenemedSynthesis),

2011 Jo Y

J. Biol. Chem.,Apr 2011; 286:15022 - 15031.

Membrane-associatedUbiquitin LigaseComplexContaining gp78Mediates Sterol-accelerated


Rabbit polyclonal anti-SPFH1 andSPFH2 were generated byimmunizing animals with keyholelimpet hemocyanin-conjugatedpeptides (Genemed Synthesis, Inc.)

2011 Liu R

Learn. Mem.,Mar 2011; 18:245 - 249.

Serotonin- andtraining-induceddynamic regulationof CREB2 in Aplysia


The anti-CREB2 antibody wasraised by a commercial vendor(Genemed Synthesis, Inc.)

2011 Zhang J

Biochimie,Volume 93,Issue 10,October 2011,Pages 1710-1719

Pathophysiologicalcondition changesthe conformation ofa flexible FBG-related protein,switching it frompathogen-recognition to host-interaction

custompeptide

Following the identification of theinteraction domain of FBG byHDMS, we performed SPR analysisto confirm the exclusion ofregion 205e220, which is not pH-and calcium-sensitive, from thebinding interface. Peptide 205e220(RVDLVDFEGNHQFAKY) wasverifie

2011 Rawal S

Toxicology andAppliedPharmacology,In Press,Corrected Proof

Metabolism ofaflatoxin B1 inTurkey livermicrosomes: Therelative roles ofcytochromes P4501A5 and 3A37

custompeptide

Rabbit polyclonal anti-P450 1A5(Yip and Coulombe, 2006) and 3A37(Rawal et al., 2010b) sera wereraised against the peptidesequences“FLDFNKRFMKLLKTAVEE (aminoacids 260–277)” and“SQKSDSDGKNSHKA (amino acids278–291),”respectively by Genemed Synthesis

2011 Li J

Journal ofNeuroimmunology, Volume 234,Issues 1-2, May2011, Pages 109-114

Differential levels ofresistance todisease inductionand development ofrelapsingexperimentalautoimmune

custompeptide

. Myelin antigen peptides weresynthesized by Genemed Synthesis(San Antonio, TX).

2011 Licht-Murava A

Journal ofMolecularBiology, Volume408, Issue 2, 29April 2011,Pages 366-378

ElucidatingSubstrate andInhibitor BindingSites on theSurface of GSK-3βand the Refinement

custompeptide

Peptides were synthesized byGenemed Synthesis, Inc.(San Francisco, CA, USA).

2011 Leung M

BiophysicalJournal, Volume100, Issue 8, 20April 2011,Pages 1960-1968

IncreasingHydrophobicity ofResidues in an Anti-HIV-1 Env PeptideSynergistically

custompeptide

). AllC-peptides were synthesized byGenemed Synthesis (San Antonio,TX).

2011 Zhao J

Biochemical andBiophysicalResearchCommunications, Volume 407,Issue 3, 15 April2011, Pages 501-506

A novel strategy toactivatecytoprotectivegenes in the injuredbrain

custompeptide

The following peptides weresynthesized by Genemed Synthesis(San Antonio, TX):TAT: NH2-YGRKKRRQRRR-CONH2TAT–DEETGE: NH2-YGRKKRRQRRRPLQLDEETGEFLPIQ-CONH2TAT–CAL–DEETGE: NH2-YGRKKRRQRRRPLFAERLDEETGEFLPCONH2

2011Palomares-Jerez M

Biochimica etBiophysica Acta(BBA) -Biomembranes,Volume 1808,Issue 4, April2011, Pages1219-1229

Membraneinteraction ofsegment H1(NS4BH1) fromhepatitis C virusnon-structuralprotein 4B

custompeptide

1. Peptides NS4BH1 (sequence 198GEGAVQWMNRLIAFASRG 215)and scrambled peptide NS4BH1SC(SAVRNAFIGQGMGRWEAL) weresynthesized with N-terminalacetylation and C-terminal amidationon an automatic multiple synthesizer(Genemed Synthesis, SanAntonio, TX, U

2011 Ren ZJ. Neuroimmuno;233, 147-159

IRF-1 signaling incentral nervoussystem glial cellsregulatesinflammatorydemyelination

custompeptide

Each immunized mouse received200 μg o f MOG3 5–5 5(MEVGWYRSPFSRVVHLYRNGK)(Genemed Synthesis, SanFrancisco, CA) emulsified incomplete Freund's adjuvant (CFA)containing 600 μg of Mycobacteriumtuberculosis H37Ra (Difco, Detroit,MI) intradermally.

2011 Richards MJ. Autoimm; 36:142-154

Virus expandedregulatory T cellscontrol diseaseseverity in theTheiler’s virusmouse model of MS

custompeptide

All synthetic peptides were obtainedfrom Genemed Synthesis, SanFrancisco, CA. These included:TMEV peptides VP2121e130(FHAGSLLVFM), VP2165e173(TGYRYDSRT), VP3110e120(NFLFVFTGAAM),VP3159e166 (FNFTAPFI),VP3173e181 (QTSYTSPTI),VP111e20(SNDDASVDFV),

2011Kanakasabai S

Brain Res; 1376:101-112

PPARδ deficientmice developelevated Th1/Th17responses andprolongedexperimentalautoimmuneencephalomyelitis

custompeptide

The 21 amino acid peptide[MEVGWYRSPFSRVVHLYRNGK]corresponding to the mouseMOGp35-55 (96.81% purity) wasobtained from Genemed SynthesisInc. (San Francisco, CA)

2011 Nakorn P

Journal ofTheoreticalBiology, Volume270, Issue 1, 7February 2011,

In vitro and in silicobinding study of thepeptide derivedfrom HIV-1 CA-CTD and LysRS as

custompeptide

Two peptides called wh-H4 and sh-H4 were purchasedfrom Genemed Synthesis Inc (USA).

2011 Rahman A

Journal ofProteomics,Volume 74,Issue 2, 1February 2011,Pages 231-241

Biomolecularcharacterization ofallergenic proteinsin snow crab(Chionoecetesopilio) and de novosequencing of thesecond allergenarginine kinaseusing tandem massspectrometry

custompeptide

sampling was bought from SKC Inc.(Eighty Four, PA, USA). Thesignature pept ide, LVSAVNEIEK(pur i t y > 98.33%; molarmass =1101.27 Da) and itsdeuterated isotopic homolog usingd3-L-alanine (purity > 96.80%; molarmass 1104.27 Da) werepurchased from

2011 Hansen K

Biochemical andBiophysicalResearchCommunications, Volume 404,Issue 1, 7January 2011,Pages 184-189

The Drosophilagenes CG14593and CG30106 codefor G-protein-coupled receptorsspecificallyactivated by theneuropeptidesCCHamide-1 and

custompeptide

We tested a library of eight biogenicaminesand 25 Drosophila neuropeptides(Supporting Information, Table S1and the novel Drosophilaneuropeptides CCHamide-1 and -2(synthesized by GenemedSynthesis, San Antonio, USA)

2011 Nicholson C

AntiviralResearch,Volume 89,Issue 1, January2011, Pages 71-74

Viral entry inhibitorsblock dengueantibody-dependentenhancement invitro

custompeptide

DN59(MAILGDTAWDFGSLGGVFTSIGKALHQVFGAIY)(Hrobowski et al., 2005) and 1OAN1(FWFTLIKTQAKQPARYRRFC)(Costin et al., 2010.) weresynthesized by solid-phase N- -9-flurenylmethyl-oxycarbonylchemistry, purified by HPLC, andconfirmed by mass spectrometry(Genem

2011 Canaday D

CellularImmunology,Volume 266,Issue 2, 2011,Pages 187-191

Preserved MHC-IIantigen processingand presentationfunction in chronicHCV infection

custompeptide

incubated with titratedconcentrations of hen egg lysozyme(HEL, Roche) or HEL peptide (aa14–37,Genemed Synthesis) in DMEMbased medium with 10% FCS.

2011 Li J

Journal ofNeuroimmunology, Volume 230,Issues 1-2,January 2011,Pages 26-32

T cells that triggeracute experimentalautoimmuneencephalomyelitisalso mediatesubsequent

custompeptide

Myelin antigen peptides weresynthesized by Genemed Synthesis(South San Francisco, CA)

2011 Jiang F

J. Pharmacol.Exp. Ther., Jul2011; 338: 134 -142.

ABT-869, aMultitargetedReceptor TyrosineKinase Inhibitor,Reduces TumorMicrovascularityand Improves

custompeptide

synthetic VEGFR 2 peptide(Tyr1214; Genemed Synthesis, SanFrancisco, CA)

2011 Ren ZJ. Neurosci; 31:8329 - 8341

Overexpression ofthe Dominant-Negative Form ofInterferonRegulatory Factor 1in OligodendrocytesProtects against

custompeptide

oligodendroglial protein (MOG)35-55(MEVGWYRSPFSRVVHLYRNGK;Genemed Synthesis)

2011 Xu M

Cardiovasc Res,May 2011; 90:325 - 334.

The endothelium-dependent effect ofRTEF-1 in pressureoverload cardiachypertrophy: role of

custompeptide RTEF-1 (Genemed Synthesis Inc.)

2011 Quintarelli CBlood, Mar 2011;117: 3353 - 3362.

High-aviditycytotoxic Tlymphocytesspecific for a newPRAME-derivedpeptide can target

custompeptide

All peptides were obtained fromGenemed Synthesis.

2011 Sayed S

J. Immunol., Mar2011; 186: 3294 - 3298.

Cutting Edge: MastCells RegulateDisease Severity inaRelapsing–Remittin

custompeptide

Mice were immunized as previouslydescribed (20) with 100 mugproteolipid protein139-151 peptide(Genemed Synthesis)

2011 Alby K

PNAS, Feb2011; 108: 2510 - 2515

Interspeciespheromonesignaling promotesbiofilm formationand same-sex

custompeptide

Peptides were synthesized byGenemed Synthesis.

2011SwaisgoodC

Am. J. Respir.Cell Mol. Biol.,Feb 2011; 44:166 - 174.

Development of aSarcoidosis MurineLung GranulomaModel UsingMycobacterium

custompeptide

Each peptide was synthesized bysolid-phase F-moc chemistry(Genemed Synthesis, San Diego,CA)

2011 Maestro B

Protein Eng.Des. Sel., Jan2011; 24: 113 -122.

Structuralautonomy of a β-hairpin peptidederived from thepneumococcal

custompeptide

protocols and purified by reversed-phase HPLC to 95% purity byGenemed Synthesis, Inc.

2011 Song B

J. Biol. Chem.,Dec 2010; 285:41122 - 41134.

InhibitoryPhosphorylation ofGSK-3 by CaMKIICouplesDepolarization to

custompeptide

myr-Ser-9-tide (RPRTTSFAESC)were synthesized by GenemedSynthesis, Inc

2011 Vatner R

J. Immunol., Dec2010; 185: 6765 - 6773.

The TaillessComplexPolypeptide-1 RingComplex of theHeat Shock Protein60 FamilyFacilitates Cross-

custompeptide

All peptides were synthesized byGenemed Synthesis (South SanFrancisco, CA)

2011 McDermott J

Mol. Biol. Cell,Nov 2010; 21:3934 - 3941.

Jen1p: A HighAffinity SeleniteTransporter in Yeast

custompeptide

synthetic peptide(QDQGVEYEEDEEDKPNLSA)derived from a putative extracellularloop of Jen1p conjugated withcarrier Keyhole Limpet hemocyanin(Genemed Synthesis, San Antonio,TX).

2011 Aaron W.M

J. Immunol., Dec2011; 187: 5921 - 5930.

Structure-BasedSelection of SmallMolecules To AlterAllele-Specific MHCClass II AntigenPresentation

custompeptide

Peptides (Genemed Synthesis) forstimulation were HPLC purified(95%) and dissolved...biotinylatedpeptides (B:9-23, HEL11-25, andEalpha52-68 from GenemedSynthesis) in binding buffer (20 mMHEPES and 150 mM NaCl, pH 7.4...…

2011 mansi S

J. Immunol., Dec2011; 187: 5865 - 5878.

CpG ProtectsHuman MonocyticCells against HIV-Vpr–InducedApoptosis byCellular Inhibitor ofApoptosis-2through theCalcium-Activated

custompeptide

The mutantVpr peptide with three arginine toalanine mutations at sites R73, R77,andR80 and indicated in bold letters inthe above sequence wassynthesized(Genemed Synthesis).

2011 lalith D

J. Biol. Chem;286: 40943 -40953

TyrosinePhosphorylation asa ConformationalSwitch: A CASESTUDY OFINTEGRIN β3CYTOPLASMICTAIL

custompeptide

Short tyrosine(s)-phosphorylatedpeptidescorresponding to NMP 3 andBP 3Pep,(720TIHDRKEFAKFEEERARAKWDTANNPLpYK748)and(736RAKWDTANNPLpYKEATSTFTNITpYRGT762)respectively, werechemically synthesized (GenemedSynthesis, Inc.).

2011 Benoît C

J. Virol., Nov2011; 85: 11833 - 11845.

Transmission ofClonal Hepatitis CVirus GenomesReveals theDominant butTransitory Role ofCD8+ T Cells inEarly Viral Evolution

custompeptide

Overlappingpeptides (18-mers overlapping by11) covering the entire HCV proteinsequence(GenBank accession no. AF009606)were obtained from GenemedSynthesis.

2011 Barrette RW

Clin. VaccineImmunol., Nov2011; 18: 1996 -1998.

Use of InactivatedEscherichia coliEnterotoxins ToEnhanceRespiratoryMucosalAdjuvanticity duringVaccination inSwine

custompeptide

intranasally inoculated with 100 mugof TCA peptide (reconstituted in 400mul of water, the volume given toeach animal) (Genemed SynthesisInc., South San Francisco, CA) atweeks 1, 2, 3, and 5, with aparenteral boost given at week 4with MPL+TDM+CWS RI

2011 Bahl N

J. Biol. Chem.,Oct 2011; 286:37793 - 37803

Delineation ofLipopolysaccharide(LPS)-binding Siteson Hemoglobin:FROM IN SILICOPREDICTIONS TOBIOPHYSICALCHARACTERIZATION

custompeptide

Based on the computationalpredictions, various Hb peptideswere synthesized commerciallyby Genemed Synthesis, Inc. andpurified to 95% underpyrogen-free conditions. The purityand quality of the peptideswere assessed by HPLC and massspectrometry. Th

2011 Lancioni C

Am. J. Respir.Crit. Care Med.,Oct 2011;10.1164/rccm.201107-1355OC

CD8+ T cellsProvide anImmunologicSignature ofTuberculosis inYoung Children

custompeptide

Peptides were synthesized byGenemedSynthesis(http://www.genemedsyn.com/). Asingle synthetic peptide poolconsisting of15-mers overlapping by 11 aa,representing Mtb-specific proteins,CFP-10 and ESAT-6,was synthesized.

2011 Zhang Q

PNAS, Oct 2011;108: 16922 -16926

Disruption of insectdiapause usingagonists and anantagonist ofdiapause hormone

custompeptide

The DH peptideused in these experiments wassynthesized by Genemed Synthesis,Inc., basedon the deduced amino acidsequence of DH from H. zea (20).

2011 Ongeri EM

Am J PhysiolRenal Physiol,Oct 2011; 301:F871 - F882

Villin and actin inthe mouse kidneybrush-bordermembrane bind toand are degradedby meprins, aninteraction thatcontributes to injuryin ischemia-reperfusion

custompeptide

To identify proteins that interact withmeprinsin the mouse kidney, a 26 aminoacid biotinylated C-terminalmouse meprin peptide(YCTRRKYRKKARANTAAMTLENQHAF;Genemed Synthesis, SanFrancisco, CA) was used.

2011 Getts DRJ. Immunol; 187:2405 - 2417

Tolerance Inducedby ApoptoticAntigen-CoupledLeukocytes IsInduced by PD-L1+and IL-10–ProducingSplenicMacrophages andMaintained by TRegulatory Cells

custompeptide

Synthetic peptides myelinoligodendrocyte glycoprotein(MOG)35–55(MEVGWYRSPFSRVVHLYRNGK),proteolipid protein (PLP)139–151(HSLGKWLGHPDKF), andOVA323–339(ISQAVHAAHAEINEAGR) werepurchased from Genemed Synthesis

2011 Bogunovic D

Cancer Res.,Aug 2011; 71:5467 - 5476

TLR4 Engagementduring TLR3-InducedProinflammatorySignaling inDendritic CellsPromotes IL-10–MediatedSuppression of

custompeptide

For the human studies, FluMP58–66 (GILGFVFTL), MelanA/Mart-126–35 (ELA modified)ELAGIGILTV, and HIV Gag77–85SLYNTVATL peptides weresynthesized by Genemed SynthesisInc.

2011 Lee RHC

Am J PhysiolHeart CircPhysiol, Aug2011; 301: H344- H354

Sympathetic α3β2-nAChRs mediatecerebral neurogenicnitrergicvasodilation in theswine

custompeptide

-conotoxin AuIB ( -CTX AuIB)and -conotoxinMII ( -CTX MII) were synthesizedby Genemed Synthesis (SanAntonio, TX) based on reportedpeptide sequences (6, 28)

2011 Slupianek ABlood, Jul 2011;118: 1062 - 1068

Targeting RAD51phosphotyrosine-315 to preventunfaithfulrecombinationrepair in BCR-ABL1leukemia

custompeptide

Synthetic fusion peptides(aptamers) containing 16 aminoacids sequencesurrounding RAD51(Y315) werepurchased from (GenemedSynthesis).ETRICKIpYDSPCLLEA-GGG-YARAAARQARA (pY315) containedphosphotyrosine (pY) in the positioncorresponding to Y315; and in

2011 Zhou X

J. Biol. Chem.,Jul 2011; 286:22855 - 22863

Arsenite InteractsSelectively withZinc FingerProteins ContainingC3H1 or C4 Motifs

custompeptide

The N-terminally acetylatedand C-terminally amidated peptidesderived from the first zincfinger of human PARP-1(apoPARPzf), aprataxin(apoAPTXzf),and specific site-directed mutations(see Fig. 3 and supplementalTable S1) were commerciallysynthesized

2011SwaisgoodC

Am. J. Respir.Cell Mol. Biol.,Feb 2011; 44:166 - 174

Development of aSarcoidosis MurineLung GranulomaModel UsingMycobacteriumSuperoxideDismutase APeptide

custompeptide

.AAAIAGAFGSFDKFR, wassynthesized as described previously(11). Each peptide was synthesizedby solid-phase F-moc chemistry(Genemed Synthesis, San Diego,CA) to a purity of greater than 70%.

2011 Wnek SM

Toxicology andAppliedPharmacology257 (2011) 1–13

Interdependentgenotoxicmechanisms ofmonomethylarsonous acid: Role ofROS-induced DNAdamage andpoly(ADP-ribose)polymerase-1inhibition in the

custompeptide

The zinc fingerPARP-1 peptide (PARPzf) wascommercially synthesized byGenemedSynthesis Inc., (San Antonio, TX)and is comprised of the followingamino acid sequence(GRASCKKCSESIPKDKVPHWYHFSCFWKV).

2011 Collin C

Biochemical andBiophysicalResearchCommunications412 (2011)578–583

Identification of theDrosophila andTribolium receptorsfor the recentlydiscovered insectRYamideneuropeptides

custompeptide

We tested eight Drosophilaneuropeptideswith an RFamide or RWamide C-terminus and the novelneuropeptides Drosophila RYamide-1 and -2 and Tribolium RYamide-1 and -2 (all synthesized byGenemed Synthesis, San Antonio,USA).

2011 Lowery A

Journal ofControlledRelease 150(2011) 117–124

Tumor-targeteddelivery ofliposome-encapsulateddoxorubicin by useof a peptide thatselectively binds toirradiated tumors

custompeptide

Preparation and drug-loading of theliposomes were carried out asdescribed [26–28]. Briefly,liposomes were made withcholesterol and1,2-Distearoyl-sn-Glycero-3-Phosphocholine (DSPC) at a molarratio ofcholesterol:DSPC=45:55. Maleimide-PEG2000-DSPE (1,

2011 Yang. JPlant Biology 13(2011) 431–438

Expressionanalyses ofAtAGP17 andAtAGP19, twolysine-richarabinogalactanproteins, inArabidopsis

custompeptide

Peptides (20amino acids in length) weresynthesised (Genemed Synthesis,San Francisco, CA, USA)encompassing the Lys-rich regionsof the AGPs

2011 Zhu Q

The Prostate71:835 ^ 845(2011)

SuppressionofGlycogenSynthaseKinase3ActivityReducesTumorGro

custompeptide

L803-mts (N-Myristol-GKEAPPAPPQSpP) wassynthesized by GeneMedSynthesis as previously described

2011 Chou H

Clinical &ExperimentalAllergy, 41 :739–749

Transaldolases arenovel andimmunoglobulin Ecross-reactingfungalallergens

custompeptide

In addition, a peptide covering theaminoacid sequence from Thr257 toSer278(TDAVPQKLKAEDVAKLDIEKKS)of Cla c 14.0101 was also customsynthesized(Genemed Synthesis Inc., SanAntonio, TX, USAq

2011 Park HJEMBO Mol Med3, 21–34

Deregulation ofFoxM1b leads totumourmetastasis

custompeptide

Genemed Synthesis, Inc.manufactured the WT ARF26–44peptide(rrrrrrrrrKFVRSRRPRTASCALAFVN) or mutant ARF37–44 peptide(rrrrrrrrrSCALAFVN) containing nineD-Arg (r) residues at the Nterminus to enhance cellular uptakeof polypeptide

2011 Sayed BAJ. Immunol;186:3294 - 3298

Cutting Edge: MastCells RegulateDisease Severity inaRelapsing–Remitting Model of MultipleSclerosis

custompeptide

Mice were immunized as previouslydescribed (20) with 100 mgproteolipidprotein139–151 peptide (GenemedSynthesis) emulsified in 5 mg/mlCFA (VWR

2011 Denning WLPLoS ONE 6(2):e16897

LimitedTransplantation ofAntigen-ExpressingHematopoieticStem Cells InducesLong-LastingCytotoxic T CellResponses

custompeptide

MHC class I-restricted OVA-1(OVA257–264, SIINFEKL) and MHCclass II-restricted OVA-2(OVA323–339,ISQAVHAAHAEINEAGR) peptideswere synthesized by GenemedSynthesis (South Francisco, CA).

2011 Uhal BD

Am J PhysiolLung Cell MolPhysiol, Sep2011; 301: L269 - L274

Regulation ofalveolar epithelialcell survival by theACE-2/angiotensin1–7/Mas axis dna

Antisense oligonucleotides againstmurine maswere designed using AntiSenseDesign software (Integrated DNATechnologies, Coralville, IA) andwere synthesized asphosphorothioated20-mers (Genemed Synthesis, SanAntonio, TX)

2011 Al Tassan N

HUMANMUTATION;Volume 33,Issue 2,February 2012,Pages:351–354,Volume33, Issue2,(351–354)

A MissenseMutation in PIK3R5Gene in a Familywith Ataxia andOculomotor Apraxia dna

Expression analysis of PIK3R5 wasperformed using first-strandcDNA libraries from commerciallyavailable multiple human adultand fetal tissues (GenemedSynthesis, Inc., South SanFrancisco andCapital Biosciences, Inc., Rockville)and primers specific f

2011KoshyCherian A

JOURNAL OFNEUROSCIENCE RESEARCH;Volume 89,Issue7(1114–1124)

Quantitative RT-PCR andimmunoblotanalyses revealacclimated A2noradrenergicneuron substratefuel transporter,glucokinase,phospho-AMPK,and dopamine-β-hydroxylaseresponses tohypoglycemia dna

MCT2: forward:50-CTAGGCTTAA-CTACTCTACATA-CC-30, reverse: 50-CGGAGGAAGTGGGAATGG-30; GLUT3: forward: 50-GAGA-GTCCAAGGTTCTTGCTC-30, reverse: 50-GCTGAGACAACTGGAGGACAA-30; GLUT4: forward: 50-CAGCACTTTAGCCCTCTCTTCC-30, reverse: 50-CCA

2011Carren˜o F.R.

Journal ofNeuroendocrinology, 23, 894–905

Brain-DerivedNeurotrophicFactor-TyrosineKinase B PathwayMediatesNMDA ReceptorNR2B SubunitPhosphorylation inthe Supraoptic dna

Forward andreverse primers for target genes(Table 1) were based on publishedsequences (42–44) and wereobtained from Genemed Synthesis,Inc. (SanFrancisco, CA, USA).

2011 Verduzco D

Methods in CellBiology, Volume101, 2011,Chapter Chapter

Analysis of CellProliferation,Senescence, andCell Death in misc

2011Hama-Tomioka

Br. J. Anaesth.,Nov 2011;10.1093/bja/aer368.

Roles of neuronalnitric oxidesynthase, oxidativestress, and propofolin N-methyl-D-aspartate-induced Miscl

gp91ds-tat and sgp91ds-tat(GenemedSynthesis Inc., San Antonio, TX,USA),

2011 Fagone P

Clinical and ExpImmunol, 163:368–374

Prevention ofclinical andhistological signs ofproteolipid protein(PLP)-inducedexperimentalallergicencephalomyelitis(EAE) inmice by the water-soluble carbon Miscl

Proteolipid protein (PLP) (139–151)was synthesized byGenemed Synthesis (SanFrancisco, CA, USA).

2011McFaline-Figueroa JR

Aging Cell (2011)10, pp885–895

Mitochondrialquality controlduring inheritanceis associatedwith lifespan andmother–daughterage asymmetry inbudding yeast Miscl

RLS measurements were taken asdescribed previously (Erjavec et al.,2008), with or without alpha-factorsynchronization. Briefly, frozen yeaststrain stocks (stored at )80 C)were grown in rich, glucose-basedsolidmedium (YPD) at 30 C. Singlecolonies

2012 Mikani APeptides; 34:135-144

Brain-midgut shortneuropeptide Fmechanism thatinhibits digestiveactivity of theAmericancockroach,Periplanetaamericana uponstarvation


Automated Edman degradationrevealed the following sequence forthe C-terminal of the peptide15 in P. americana: Ala-Asn-Arg-Ser-Pro-Ser-Leu-Arg-Leu-Arg-Phe[32]. Strong homology between16 this peptide and sNPF-likesequences has been identified inothe

2012Pandurangan S

J. Exp. Bot; 63:3173 - 3184

Relationshipbetweenasparaginemetabolism andproteinconcentration insoybean seed


An antibody wasraised against the following peptidein the a-subunit of matureASPGB1a and -b: NH2-ASIMDGPKRRCGAVSC-COOH, byGenemed Synthesis (San Antonio,TX, USA).

2012 Cuddy LKJ. Neurosci; 32:5573 - 5584

Peroxynitrite DonorSIN-1 Alters High-Affinity CholineTransporter Activityby Modifying ItsIntracellularTrafficking


Polyclonal CHT antibodywas raised in rabbits to the antigenicpeptide DVDSSPEGSGTEDNLQ,which is conserved at the Cterminus of human and rat CHT(GenemedSynthesis); this peptide wasconjugated to KLH carrier protein byanN-terminal cysteine residue.

2012 Wu JPNAS; 109: 5675- 5680

HistoneH3R17me2a markrecruits humanRNA Polymerase-Associated Factor1 Complex toactivatetranscription


RTKQTARKSTGGKAP-R(me)2aKQL] and Biotin-conjugatednegative control peptide(TGIVNHTHSRMGSIMSTGIV) weresynthesized by Genemed Synthesis.

2012 Chang AJ. Virol; 86: 3230- 3243

HumanMetapneumovirus(HMPV) Bindingand Infection AreMediated byInteractionsbetween the HMPVFusion Protein and


Antipeptide antibodiesagainstHMPVF (GenemedSynthesis,San Francisco, CA) were generatedusing amino acids 524 to 538of HMPV F.

2012 Shao WMol. Cell. Biol;32: 470 - 478

A U1-U2 snRNPInteraction Networkduring IntronDefinition


Antiserum against SF3b155 wasgeneratedby immunizing rabbits with331EKELPAALPTEIPGVC peptide(Genemed Synthesis Inc.).

2012 Schein V

General &ComparativeEndocrinology;175: 344-356

Four stanniocalcingenes in teleostfish: Structure,phylogeneticanalysis, tissuedistribution andexpression duringhypercalcemicchallenge


STC polyclonal antisera used forimmunohistochemistry (IHC)were raised in rabbits againstsynthetic peptides with thesequencesCQPGFRGRDPTHLFA (STC1-A),CPTGVEGRGSWRFSMPH(STC1-B) and CHPRSRSQRPRRQSPEAG(STC2-A), conjugated to keyholelimpet hemocyanin (

2012 Harvey WR

J. InsectPhysiology; 58:590-598

K+ pump: Fromcaterpillar midgut tohuman cochlea


Affinity purified polyclonal antibodies(anti-KHA2) used herewere characterized previously(Xiang et al., 2007). Briefly, a 15-residuepeptide(24SMHQEAQEFTVMKLK38C) ofhuman KHA2 (geneaccession number NM_178833)was used to inject two rabbits toraise

2012 Jiang R

Intl. J. Biochem& Cell Bio;44:91– 100

Apo- and holo-lactoferrin stimulateproliferation ofmouse crypt cellsbut throughdifferent cellular


Antiserum was produced in rabbitsagainst a synthesized peptideCTVGDRWSSQQGSKAD of LfR(Genemed, San Antonio, TX).

2012 Jones BL

ComparativeBiochemistry andPhysiology; 162:193–199

Thermostableproteins in thediapausing eggs ofBrachionusmanjavacas


Genemed Synthesis Inc. preparedpolyclonal antisera in rabbitsagainst both the putative LEA andVTG proteins.

2012 Fan J

DevelopmentalBiology; 366:172–184

Hh-inducedSmoothenedconformationalswitch is mediatedby differentialphosphorylation atits C-terminal tail ina dose- andposition-dependentmanner


Theanti-SmoPantibodywasgeneratedbyGenemedSynthesisInc.byinjectingtheantigenpeptideCRHVSVESRRN(pS)VD(pS)QV(pS)VKintorabbits.Theserumwasaffinity-purifiedwiththeantigenandtheflowthroughwaskeptasacontrolantibodyagainstnon-phosphory-latedpeptide.

2012 Liu YSci. Signal; 5:ra77.

Akt Phosphorylatesthe TranscriptionalRepressor Bmi1 toBlock Its Effects onthe Tumor-Suppressing Ink4a-Arf Locus


A Bmi1 phospho(Ser316) peptide(SFANRPRKSSPVNGS) wassynthesizedand injected into rabbits. Antiserumwas obtained and affinity-purifiedaccording to the manufacturer’sprocedures (Genemed SynthesisInc.). ForWestern blot analysis, the Bmi1phospho(Ser31

2012 Chang AJ. Virol; 86: 9843- 9853

PotentialElectrostaticInteractions inMultiple RegionsAffect HumanMetapneumovirus


Antipeptide antibodies againstHMPV F (Genemed Synthesis, SanFrancisco,CA) were generated using aminoacids 524 to 538 of HMPV F.

2012 Zhao YJSci. Signal; 5:ra67.

The Membrane-Bound EnzymeCD38 Exists in TwoOpposingOrientations


Monoclonal and polyclonalantibodies against the first 21amino acid residues of the Nterminus of CD38 were custom-made byAbsea and Genemed Synthesis Inc.

2012 Thon JNBlood; 120: 1975- 1984.

High-content live-cell imaging assayused to establishmechanism oftrastuzumabemtansine (T-DM1)–mediatedinhibition of plateletproduction


a rabbit polyclonal primary Ab formouse or human 1-tubulingeneratedagainst the C-terminal peptidesequenceLEDSEEDAEEAEVEAEDKDHandCKAVLEEDEEVTEEAEMEPEDKGH, respectively (Genemed Synthesis).

2012 Thon JNBlood; 120: 1552- 1561.

Peptidescorresponding tothe N-terminal first23 residues(MGDWSALGKLLDKVQAYSTAGGK)or Cx43 peptideswith the G2V orW4A amino acidsubstitutions werehigh-performance


To demarcate permeabilized cells,samples wereincubated with a rabbit polyclonalprimary antibody for mouse tubulingenerated against the C-terminalpeptide sequenceLEDSEEDAEEAEVEAEDKDH(Genemed Synthesis).

2012 Thon JNJ. Cell Biol; 198:561 - 574.

T granules inhuman plateletsfunction in TLR9organization andsignaling


To demarcate permeabilizedcells, samples were incubated witha rabbit polyclonal primary antibodyforhuman or mouse 1-tubulingenerated against the C-terminalpeptide sequenceCKAVLEEDEEVTEEAEMEPEDKGH and LEDSEEDAEEAEVEAEDKDH,respectively(Genemed Syn

2012 Meng RBlood; 120: 404 -414.

SLC35D3 deliveryfrommegakaryocyteearly endosomes isrequired for plateletdense granulebiogenesis and isdifferentiallydefective inHermansky-Pudlak


Rabbit polyclonal Ab to mouseSLC35D3 was generated byGenemedSynthesis to a synthetic peptide(CMKKDYLMENEALPSP, theC-terminal 15 residues of SLC35D3preceded by cysteine) conjugated tokeyhole limpet hemocyanin.

2012 Khoa DB

Insect MolecularBiology: 21(5),473–487

Expression ofautophagy 8 (Atg8)and its role in themidgut and otherorgans of thegreater wax moth,Galleria mellonella,


The anti-Atg8 antibody was raised intwo rabbits (Genemed SynthesisInc, San Antonio, TX, USA).

2012 Street TOJ. Mol bio; 415: 3-15

Cross-MonomerSubstrate ContactsReposition theHsp90 N-TerminalDomain and Primethe ChaperoneActivity

custompeptide

HtpG, variants of HtpG, and Δ131Δwere purified asdescribed previously.5,30 A peptidecorresponding toresidues 87–116 in Δ131Δ wassynthesized (GenemedSynthesis)

2012 Liu JQJ. Immunol; 188:3099 - 3106

Increased Th17and Regulatory TCell Responses inEBV-Induced Gene3-Deficient MiceLead to MarginallyEnhanced

custompeptide

MOG peptide 35–55(MEVGWYRSPFSRVVHLYRNGK),purchased fromGenemed Synthesis (San Antonio,TX), was used as the immunogen.

2012Kanakasabai S

J.Nut. Biochem;In Press

Differentialregulation of CD4+T helper cellresponses bycurcumin inexperimentalautoimmuneencephalomyelitis

custompeptide

The 21-amino-acid peptide[MEVGWYRSPFSRVVHLYRNGK]corresponding tomouse MOGp35-55 (N96.81% pure)was obtained from GenemedSynthesis (SanAntonio, TX, USA)

2012 Dang Y

Clin. CancerRes; 18: 3122 -3131

DendriticCell–ActivatingVaccine AdjuvantsDiffer in the Abilityto Elicit AntitumorImmunity Due to anAdjuvant-SpecificInduction of

custompeptide

(IGFBP-2) peptide 8–22 (p8,PALPLPPPPLLPLLP), 251–265(p251,GPLEHLYSLHIPNCD), and291–305 (p291,PNTGKLIQGAPTIRG;Genemed Synthesis Inc.)

2012 Prasad S

J. Autoimm, InPress, CorrectedProof

Pathogenesis ofNOD diabetes isinitiated byreactivity to theinsulin B chain 9-23epitope andinvolves functionalepitope spreading

custompeptide

Synthetic peptides Ins B9-23(SHLVEALYLVCGERG), Ins B15-23(LYLVCGERG), IGRP206-214(LRNKANAFL), GAD65509-528(VPPSLRTLEDNEERMSRLSK),GAD65524-543(SRLSKVAPVIKARMMEYGTT) werepurchased from GenemedSynthesis (San Francisco, CA).

2012NakayamaM

Diabetes; 61:857 - 865

Germline TRAV5D-4 T-Cell ReceptorSequence Targetsa Primary InsulinPeptide of NODMice

custompeptide

IFN-g enzyme-linked immunospot(ELISPOT) assay was performedaccording to the manufacturer’sinstructions(BD Biosciences). Spleen cells,harvested from retrogenic mice (7 3105 cells/well), were incubated in thepresence or absence of 100 mg/mLof antig

2012 Burke KPJ. Immunol; 188:5177 - 5188

Immunogenicityand Cross-Reactivity of aRepresentativeAncestralSequence inHepatitis C VirusInfection

custompeptide

Whenchanges away from the consensussequence occurred in the region of aCD8 T cell epitope, syntheticpeptides corresponding to thatsequence, aswell as the consensus sequence,were synthesized commercially byGenemedSynthesis (San Antonio, TX).

2012 Su MAJ. Immunol; 188:4906 - 4912

DefectiveAutoimmuneRegulator-Dependent CentralTolerance to MyelinProtein Zero IsLinked toAutoimmunePeripheralNeuropathy

custompeptide

Proliferation assay using[3H]thymidine incorporation wasperformed asdescribed previously (11). P0180–199SSKRGRQTPVLYAMLDHSRSand hen egg lysozyme (HEL) 11–25AMKRHGLDNYRGYSL peptideswere purchased from GenemedSynthesis.

2012 Skorska MNBlood; 119: 4253- 4263

Rac2-MRC-cIII–generated ROScause genomicinstability in chronicmyeloid leukemiastem cells andprimitive progenitors

custompeptide

SS31 (d-Arg-Dmt-Lys-Phe-NH2;Dmt 2 ,6 -dimethyltyrosine)and SS20 (Phe-d-Arg-Phe-Lys-NH2)peptides were purchased fromGenemedSynthesis.

2012 Busca A

J. Biol. Chem;287: 15118 -15133

Critical Role forAntiapoptotic Bcl-xLand Mcl-1 inHumanMacrophageSurvival andCellular IAP1/2(cIAP1/2) inResistance to HIV-Vpr-inducedApoptosis

custompeptide

Vpr—C-terminal Vpr (amino acids52–96) was synthesized byInvitrogen. Mutant Vpr peptide wassynthesized by Genemed SynthesisInc. (San Francisco, CA).Peptides were obtained byautomated solid-phase synthesisusing 9-fluorenylmethoxycarbonyland purified

2012 Wu YJ. Biol. Chem;287: 5744 - 5755

A ChemokineReceptor CXCR2MacromolecularComplex RegulatesNeutrophilFunctions inInflammatoryDiseases

custompeptide

The human andmurine CXCR2 C-tail peptides(biotin-conjugate at N terminus):WT (biotin-FVGSSSGHTSTTL forhuman CXCR2 C-tail; andBiotin-FVSSSSANTSTTL for mouseCXCR2 C-tail), PDZ motifdeletion, TTL or PDZ motif mutant,AAA, were synthesized byGenemed

2012 Kim KMol. Cell. Biol;32: 783 - 796

Vpr-Binding ProteinAntagonizes p53-MediatedTranscription viaDirect Interactionwith H3 Tail

custompeptide

The peptides corresponding to theN-terminal tail of H3 (amino acids 1to 28) were synthesized byGenemedSynthesis Inc. (South SanFrancisco, CA) by solid-phaseFmoc/tBu chemistryusing an automated peptidesynthesizer.

2012 Wang G

Antimicrob.AgentsChemother; 56:845 - 856

Decoding theFunctional Roles ofCationic SideChains of the MajorAntimicrobialRegion of HumanCathelicidin LL-37

custompeptide

GF-17 GFKRIVQRIKDFLRNLV-NH27.5 7.5K18A GFARIVQRIKDFLRNLV-NH215 7.5R19A GFKAIVQRIKDFLRNLV-NH215 7.5R23A GFKRIVQAIKDFLRNLV-NH260 15K25A GFKRIVQRIADFLRNLV-NH260 7.5R29A GFKRIVQRIKDFLANLV-NH215 7.5GE-18 GEFKRIVQRIKDFLRNLV-NH2 60 60GE-18K GEFKKIVQ

2012 Kuo CJJ. Biol. Chem;287: 1892 - 1902

Novel MycobacteriaAntigen 85Complex BindingMotif on Fibronectin

custompeptide

Synthesizedpeptides (Table 2) were orderedfrom Genemed Synthesis(San Antonio, TX).Peptide SequenceP1–16 AIDAPSNLRFLATTPNP14–26 TPNSLLVSWQPPRP25–38 PRARITGYIIKYEKP37–52 EKPGSPPREVVPRPRPP51–66 RPGVTEATITGLEPGTP63–78 EPGTEYTIYVIALKNNP77–90 NNQKSEPL

2012 Mora-pale M

Free Radical Bio& Med; 52: 962-969

Trimer hydroxylatedquinone derivedfrom apocynintargets cysteineresidues ofp47phox preventingthe activation ofhuman vascularNADPH oxidase

custompeptide

A proline-rich p22phox peptide N′-151PPSNPPPRPPAEARK165-C′,which was biotinylated at the N-terminus and amidated at theCterminus,was obtained from GenemedSynthesis, Inc. (South SanFrancisco, CA, USA).

2012 Menousek J

InternationalJournal ofAntimicrobialAgents; 39: 402-406

Databasescreening and invivo efficacy ofantimicrobialpeptides againstmethicillin-resistantStaphylococcusaureus USA300

custompeptide

All peptides used in this study werechemically synthesisedand purified to >95% (GenemedSynthesis Inc., SanAntonio, TX), with peptide qualityverified by reverse-phasehigh-performance liquidchromatography (HPLC) prior to use.

2012ChagoyánHS

ComparativeBiochemistry andPhysiology; 161:450–455

Pigment dispersinghormonemodulatesspontaneouselectrical activity ofthe cerebroidganglion andsynchronizeselectroretinogramcircadian rhythm in

custompeptide

PDH purchased from GenemedSynthesis with sequenceNSELINSILGLPKVMNEA,corresponding to beta-PDH incrayfish P. clarkii wasdissolved and diluted in vanHarreveld (VH) saline solutionmodifiedby Miller and Glantz (2000).

2012 Liu L

Biochem &Biophy ResCommun; 417:153–156

Zinc-mediatedmodulation of theconfiguration andactivity ofcomplexesbetween copperand amyloid-β

custompeptide

Lyophilized Ab(1–16)(DAEFRHDSGYEVHHQK) wassynthesizedby Genemed Synthesis (SanAntonio, TX) and purified in-houseusing HPLC.

2012 Yaniv O

Methods inEnzymology;510: 247-259

InteractionsBetween Family 3CarbohydrateBinding Modules(CBMs) andCellulosomal LinkerPeptides

custompeptide

Consensus C. thermocellum CipALinker peptide. The linker peptidedoes not contain any additional tag.It was synthesized chemically(Genemed Synthesis, Inc., TX,USA) and purified by HPLC (purityof more than 95%).

2012 Wu REMBO Mol Med;4: 1–14

Hexokinase IIknockdown resultsin exaggeratedcardiac hypertrophyvia increased ROSproduction

custompeptide

A peptide analogous to the N-terminal sequence of HKII (n-HKII:MIASHLLAYFFTELNHDQVQKVD),along with a scrambled peptide(Scram:VLIQKEVTDNLAFYMSHADHQLF)were synthesized by GenemedSynthesis,Inc., San Antonio, TX.

2012 Doyer MV

ANNALS OFNEUROLOGYAcceptedmanuscript online

Aquaporin-4-specific T cells inneuromyelitis opticaexhibit a Th17 biasand recognizeClostridium ABCtransporter

custompeptide

Peptides were synthesized byGenemed Synthesis Inc. with puritygreater than95% by HPLC analysis. OverlappingAQP4 20-mer peptides were offsetby 10 aminoacids (Supplementary Table 1).Peptides corresponding to certainhydrophobic AQP4sequences were sy

2012 Myoung JJ. Virol,86(24):13717

Epitope-SpecificCD8+ T Cells Playa DifferentialPathogenic Role inthe Development ofa Viral Disease

custompeptide

All peptides used were purchasedfrom GeneMed (GeneMedSynthesis Inc., CA)

2012 Ren ZJ. Immunol; 189:4602 - 4611.

Cross-Immunoreactivitybetween BacterialAquaporin-Z andHuman Aquaporin-

custompeptide

AqpZ, Aqp4, and OVA323–339(Genemed Synthesis, SanFrancisco,CA) peptides

2012

Hirschhorn-CymermanD

J. Exp. Med;209: 2113 - 2126.

Induction oftumoricidal functionin CD4+ T cells isassociated withconcomitant

custompeptide

Trp1 peptide (Muranski et al., 2008)was synthesized by GenemedSynthesis, Inc

2012 Grassie ME

J. Biol. Chem;287: 36356 -36369.

Cross-talk betweenRho-associatedKinase and CyclicNucleotide-dependent KinaseSignaling Pathwaysin the Regulation of

custompeptide

MYPT1, phosphorylated andunphosphorylated, was also used.Peptides were synthesized byGenemed Synthesis

2012 Dürrnagel SJ. Gen. Physiol;140: 391 - 402.

High Ca2+permeability of apeptide-gatedDEG/ENaC fromHydra

custompeptide

Hydra-RFamide I (pQWLGGRF-NH2)was purchased from GenemedSynthesis

2012 Green TDJ. Leukoc. Biol;92: 633 - 639.

Directed migrationof mousemacrophages invitro involvesmyristoylatedalanine-rich C-kinase substrate(MARCKS) protein

custompeptide

MANS and RNS peptides weresynthesized by Genemed Synthesis(San Antonio,TX, USA). MANS peptide is identicalto the first 24 aa of MARCKS:MA-GAQFSKTAAKGEAAAERPGEAAVA. The RNS peptide contains thesame amino acids as MANS but inrandom sequence: MA-GTAPA

2012 Shao QMol. Biol. Cell;23: 3312 - 3321.

Structure andfunctional studiesof N-terminal Cx43mutants linked tooculodentodigitaldysplasia

custompeptide

Peptides corresponding to the N-terminal first 23 residues(MGDWSALGKLLDKVQAYSTAGGK) or Cx43 peptides with the G2V orW4A amino acid substitutions werehigh-performance liquidchromatography purified, and puritywas confirmed by electron ionizationspectr

2012Parthasarathi K

Am J PhysiolLung Cell MolPhysiol; 303: L33- L42.

Endothelialconnexin43mediates acid-induced increasesin pulmonary

custompeptide

(sc-Gap27; 190 M) were used asreported (21) and werecustom generated by GenemedSynthesis (San Antonio, TX).

2012 Kinoshita HAnesth. Analg;115: 54 - 61.

IsofluranePretreatmentPreservesAdenosineTriphosphate–Sensitive K+ ChannelFunction in theHuman Artery

custompeptide

gp91ds-tat and sgp91ds-tat weresynthesized by Genemed SynthesisInc. (San Antonio, TX).

2012 Ma S

J. Biol. Chem;287: 22521 -22532.

Site-specificPhosphorylationProtects GlycogenSynthase Kinase-3β from Calpain-mediatedTruncation of Its Nand C Termini

custompeptide

Peptides, including Ser-389-tide(RIQAAASPPAN,corresponding to residues 383–393of rat GSK-3 ),Ser(P)-389-tide(RIQAAA(P)SPPAN, (P) representsa phosphate),Ser-9-tide (RPRTTSFAESC,corresponding to residues4–14 of GSK-3 ), and Ser(P)-9-tide(RPRTT(P)S

2012 Dang Y

Clin. CancerRes; 18: 3122 -3131.

DendriticCell–ActivatingVaccine AdjuvantsDiffer in the Abilityto Elicit AntitumorImmunity Due to anAdjuvant-SpecificInduction ofImmunosuppressive Cells

custompeptide

TgMMTVneu mice were vaccinatedt.d. with 50 mg of eachinsulin-like growth factor–bindingprotein-2 (IGFBP-2)Translational RelevanceSuccessful cancer vaccines willdepend on the generationof robust levels of tumor-specifictype I T cells withactive im

2012 Restivo M

Biochem &Biophy ResComm.: 426,237-241

Activation of εPKCreducesreperfusionarrhythmias andimproves recoveryfrom ischemia:Optical mapping ofactivation patternsin the isolatedguinea-pig heart

custompeptide

The membrane permeable peptides,weRACK; (eV1–7[HDAPIGYD]), which activatesePKC translocation and function[5,15] and eV1–2 [EAVSLKPT],which inhibits the translocationand function [5,15] of ePKC wereconjugated to TAT peptide[YGRKKRRQRRR] via cystein

2012Solís-Chagoyán H

ComparativeBiochem &Physiology:161,450–455

Pigment dispersinghormonemodulatesspontaneouselectrical activity ofthe cerebroidganglion andsynchronizeselectroretinogramcircadian rhythm incrayfish

custompeptide

PDH purchased from GenemedSynthesis with sequenceNSELINSILGLPKVMNEA,corresponding to beta-PDH incrayfish P. clarkii wasdissolved and diluted in vanHarreveld (VH) saline solutionmodifiedby Miller and Glantz (2000). VHcomposition (in mM) was NaCl 2

2012Kanakasabai S

J. NutritionalBiochem:23,1498–1507

Differentialregulation of CD4+T helper cellresponses bycurcumin inexperimentalautoimmuneencephalomyelitis

custompeptide

The 21-amino-acid peptide[MEVGWYRSPFSRVVHLYRNGK]corresponding tomouse MOGp35-55 (N96.81% pure)was obtained from GenemedSynthesis (SanAntonio, TX, USA).

2012 Nishikori SJ. MolBio:424,391-399

Broad Ranges ofAffinity andSpecificity of Anti-Histone AntibodiesRevealed by aQuantitative

custompeptide

Histone peptides were purchasedfrom Abgent andGenemed Synthesis.

2012Palomares-Jerez MF

Biochimica etBiophysica Acta(BBA) -Biomembranes:1818,2536-2549

Interaction withmembranes of thefull C-terminaldomain of proteinNS4B fromHepatitis C virus

custompeptide

Peptides NS4BCter(1909GEGAVQWMNRLIAFASRGNHVSPTHYVPESDAAARVTAILSSLTVTQLLRRLHQWISSECTTPC1972), NS4BH1(1909GEGAVQWMNRLIAFASRG1926) andNS4BH2(1947ILSSLTVTQLLRRLHQWI1964)(HCV strain 1a_H77 polyproteinnumbering) were synthesized withNterminalacetylati

2012 Grant MMol. Endocrinol;26: 2081 - 2091.

Calcium SignalingRegulatesTrafficking ofFamilialHypocalciuricHypercalcemia

Customproteinantibodies

polyclonalanti-CaSR [LRG epitope (25)custom generated by GenemedSynthesis,Inc., South San Francisco, CA]

2012 Smith ECBlood; 120: 2317- 2329.

MKL1 and MKL2play redundant andcrucial roles inmegakaryocytematuration and

Customproteinantibodies beta1 tubulin antibody

2012 Shinwari JHuman mutation;33: 351–354

A missensemutation in PIK3R5gene in a familywith ataxia andoculomotor apraxia dna

Expression analysis of PIK3R5 wasperformed using first-strandcDNA libraries from commerciallyavailable multiple human adultand fetal tissues (GenemedSynthesis, Inc., South SanFrancisco andCapital Biosciences, Inc., Rockville)and primers specific f

2012 Zhang XEur. J. Immunol;42: 1–12

CD24 on thymicAPCs regulatesnegative selectionof myelin antigen-specific Tlymphocytes Miscl

Splenocytes (1 106/mL) fromvarious strains of 2D2 TCRtransgenic mice with or withoutCD24-deficiency were stimulatedwith titrated MOG 35-55 peptide in96-well U-bottomed plates.3H-Thymidine was added into theculture at 48 h and harvested12 h later.

2012 Tomioka KHBr. J. Anaesth;108: 21 - 29.

Roles of neuronalnitric oxidesynthase, oxidativestress, and propofolin N-methyl-D-aspartate-induced Miscl gp91ds-tat and sgp91ds-tat

2012 Chang MC

ActaBiomaterialia; 8:1380-1387

Carboxylesteraseexpression inhuman dental pulpcells: Role inregulation ofBisGMA-induced Miscl

PCR primers were synthesized fromGenemed Biotechnologies, Inc.(San Francisco, CA, USA).

2012 Chang MCJ. Endodontics;38: 774-779

Regulation ofVascular CellAdhesion Molecule-1 in Dental PulpCells by Interleukin-1β: The Role ofProstanoids Miscl

Polymerase chain reaction (PCR)primers for b-actinand VCAM-1 were synthesized fromGenemed Biotechnologies, Inc (SanFrancisco, CA).

2012 Cherian AKJ. neurosci res;90 :1347–1358

A2 noradrenergicnerve cell metabolictransducer andnutrient transporteradaptation tohypoglycemia:Impact of estrogen Miscl

MCT2forward: 50-CTAGGCTTAACTACTCTACATACC-30,reverse: 50-CGAGGAGTGGGAA-TGG-30; GLUT3 forward:50-GAGAGTCCAAGGTTCTTGCTC-30, reverse: 50-GCTGAGACAACTG-GAGGACAA-30; GLUT4 forward:50-CAGCACTTTAGCCCTCTCTTCC-30, reverse: 50-CCACAGC-CTA

2012 Akiyama TNeuroscience:226, 305–312

Cross-sensitizationof histamine-independent itch inmouse primary Miscl

BAM8-22 (50 nmol;Genemed Synthesis Inc., SanAntonio, TX, USA).

2012 Yu B

J. Bone andMineral Res, 27,2001–2014

Parathyroidhormone inducesdifferentiation ofmesenchymalstromal/stem cellsby enhancing bonemorphogeneticprotein signaling Miscl

For BMPRII and PTH1Rcolocalization assays, we seededHEK293cells expressing YFP-BMPRII orCFP-PTH1R and treated themwith tetramethylrhodamine-labeledPTH (PTHTMR; GenemedSynthesis Inc. San Antonio, TX,USA)

2013 Militello RD

Rab24 is Requiredfor Normal CellDivision

2013 Zeng HCHEMBIOCHEM; 14: 7, 827–835

A TR-FRET-BasedFunctional Assayfor ScreeningActivators of

2013 Liang L

CellularSignalling: 25,247–254

TAK1 ubiquitinationregulatesdoxorubicin-induced NF-κBactivation


were generated by immunizingrabbits with the synthetic peptidescorresponding to amino acids-GKPIPNPLLGLDST andDYKDDDDK,respectively (Genemed Synthesis,Inc., San Antonio, TX).

2013 Matsui T

J. InsectPhysiology:59,33–37

The parsintercerebralisaffects digestiveactivities of theAmericancockroach,Periplaneta


Rabbit anti-P. americana-AST-6antibody (Genemed Synthesis,Calif., USA) was used as a primaryantibody that was conjugatedwith fluorescein.

2013PocognoniCA

Fertility andSterility: 99,0015-0282

Perfringolysin O asa useful tool tostudy human spermphysiology


anti-complexin I/II (rabbit polyclonal,purified IgG) wasfrom Synaptic Systems; rabbitpolyclonal antibody againstEpac was from Genemed Synthesis,Inc.

2013 Deng Y

DevelopmentalBiology: 375,152-159

Hippo activationthroughhomodimerizationand membraneassociation forgrowth inhibitionand organ sizecontro


TodetectactivatedHpoprotein,aphospho-Thr195specificHpoantibodywasgeneratedinrabbit(GenemedSynthesis,Inc.).

2013 Anjos L

Biochimica etBiophysica Acta:1834, 642–650

Cartilage AcidicProtein 2 ahyperthermostable,high affinity calcium-binding protein


A polyclonal antibody was producedin rabbits against recombinantsbCRTAC2 (GENEMED synthesis,GSI, USA)

2013 Bannister JPJ. Physiol; 591:2987 - 2998.

The CaV1.2channel C-terminusfragment is a bi-modal vasodilator


Antibodies used were a custom anti-CCt raised to the distal CaV1.2Cterminus(CDPGQDRAVVPEDES, GenemedSynthesis Inc.)

2013 Theos AC

Pigment CellMelanoma Res;pcmr.12084

The PKD domaindistinguishes thetrafficking andamyloidogenicproperties of thepigment cell proteinPMEL and itshomologue GPNMB


The hNMB-C rabbit antiserum wasraised byGenemed Synthesis (San Antonio,TX, USA) against a peptide(residues 543–560) mapping to theC-terminus of human GPNMBand conjugated to keyhole limpethemocyanin

2013 Wang L

Nucleic AcidsRes; 41: 6870 -6880

CARM1automethylation iscontrolled at thelevel of alternativesplicing


All peptide antibodies E16 (detectsboth isoforms ofCARM1) and me-E15 (detectsautomethylated CARM1)were generated by GenemedSynthesis Inc., TX, USA. To

2013 Cuddy LKJ. Neurochem;10.1111

Regulation of thehigh-affinity cholinetransporter activityand trafficking by itsassociation withcholesterol-rich lipidrafts


Polyclonal CHT antibodywas raised in rabbits to the antigenicpeptide DVDSSPEGSGTEDNLQthat is conserved at the carboxylterminus of human andrat CHT (Genemed Synthesis, SanAntonio, TX, USA); this peptidewas conjugated to keyhole limpethemocyanin car

2013 Hauser DN

Free Radical Bio& Med; 65:419–427

Dopamine quinonemodifies anddecreases theabundance of themitochondrialselenoproteinglutathioneperoxidase 4


ApolyclonalantibodyforGPx4wasraisedinrabbitagainstapeptidecorrespondingtotheresidues178-KRYGMEEPQVIEKD-191offull-lengthratGPx4byGenemedSynthesisInc.(San Francisco,CA).

2013 Chan SW

J. Biol. Chem;288: 37296 -37307

Actin-binding andCell ProliferationActivities ofAngiomotin FamilyMembers AreRegulated by HippoPathway-mediatedPhosphorylation


.Rabbitanti-phospho-Amotandrabbitanti-phospho-AmotL2antibodieswerecustom-madebyGenemedSynthesis, Inc.The peptide sequence of Amot usedfor raising phospho-Amot antibodywasHCGLRDLKQGHVRSLS(PO3H2)ERLMQMSLAT-OH,andthepeptidesequenceusedforraisingphospho-

2013 Sung PJPNAS; 110:20593 - 20598

Phosphorylated K-Ras limits cellsurvival by blockingBcl-xL sensitizationof inositol

custompeptide

Tail peptides were synthesizedand HPLC purified

2013 Young EE

J.Neuroimmunology: 254,19–27

Chronic socialstress impairs virusspecific adaptiveimmunity duringacute Theiler'svirus infection

custompeptide

The immunodominantCD4+ T cell peptideQEAFSHIRIPLPH corresponding toTMEV VP274–86was used to determine CD4+ cellspecific responses (Gerety et al.,1991,1994). Immunodominant CD8+ Tcell peptide FNFTAPFIcorrespondingto VP3159–166 was used to determi

2013 Clark EAJ. Virol: 87: 3361- 3375.

CD22 Is Requiredfor Protectionagainst West NileVirus Infection

custompeptide

For in vitro restimulation, 1 MCD8 Tcell-specific NS4B 9-merSSVWNATTA (31) or CD4 T cell-specificNS32066–2080 15-merRRWCFDGPRTNTILE (32) peptide(GenemedSynthesis Inc., San Antonio, TX)was added to 4 106 splenocytesculturedwith GolgiPlug con

2013 Chang YFJ. Biol. Chem:288: 3886 - 3896.

Elastin, a NovelExtracellula`r MatrixProtein Adhering toMycobacterialAntigen 85 Complex

custompeptide

Peptide SequencepHTE 27 VPGALAAAKAAKYpHTE 28GAAVPGVLGGLGALGGVGIPGGVVpHTE 29GAGPAAAAAAAKAAAKAAQFpHTE 30GLVGAAGLGGLGVGGLGVPGVGGLGpHTE 31 GIPPAAAAKAAKYpHTE 32GAAGLGGVLGGAGQFPLGpHTE 33 GVAARPGFGLSPIFPpHTE 36 GGACLGKACGRKRK

2013 Leen AMBlood; 121: 207 -218.

Immunotherapeuticstrategies toprevent and treathuman herpesvirus6 reactivation afterallogeneic stem celltransplantation

custompeptide

For stimulation, we used eithercommercially availableor custom-ordered pepmixes (15mers overlapping by 11aa) spanningU54 (JPT Technologies), U90, U11,U14, and U71 (Genemed Synthesis).

2013 Pizzo SVJ. Biol. Chem:288: 498 - 509.

The Voltage-dependent AnionChannel (VDAC)Binds Tissue-typePlasminogenActivator andPromotesActivation ofPlasminogen on the

custompeptide

The VDAC10GKSARDVFTKGYGFGLIKLDL30(Gly10–Leu30) and t-PA509CQGDSGGPLVC519peptides were obtained fromGenemed Synthesis, Inc. (SanAntonio, TX).

2013 Knepper PA

Invest.Ophthalmol. Vis.Sci; 54: 592 -601.

sCD44Internalization inHuman TrabecularMeshwork Cells

custompeptide

Cellswere also treated with 1 lg of HA orwith 1 ng of the 10-mer HAbinding peptide, KNGRYSISRT,corresponding to the first HA bindingsite of sCD44 (amino acid residues38 through 47). The 10-mer HAbinding peptide was synthesized byGenemed Synthesis,

2013Eldar-Finkelman H

J. Biol. Chem;288: 1295 - 1306.

Inhibition ofGlycogen SynthaseKinase-3Ameliorates β-Amyloid Pathologyand RestoresLysosomalAcidification andMammalian Target

custompeptide

L803-mts peptide was synthesizedby GenemedSynthesis, Inc

2013 Turula H

EUROPEANJOURNAL OFIMMUNOLOGY43:1252–1263

Competitionbetween T cellsmaintains clonaldominance duringmemory inflationinduced by MCMV

custompeptide

cells were incubated with 1 g/mlpeptide (synthesized byGenemed Synthesis -http://www.genemedsyn.com) in thepresence of 1 g/mlbrefeldin A (GolgiPlug, BDBiosciences) for 3 hours at 37 C in96-well Ubottomedplates prior to staining for intracellul

2013ScheinbergDA

ScienceTranslationalMedicine; 5:176ra33

Targeting theIntracellular WT1Oncogene Productwith a TherapeuticHuman Antibody

custompeptide

All peptides were purchased andsynthesized by Genemed SynthesisInc. Peptides were >90% pure (tableS1). The peptides were dissolvedin dimethyl sulfoxide and diluted insaline at 5 mg/ml and frozen at−80°C. Biotinylated single-chainWT1 peptide/HLA-A02

2013 Edgerton M


Candida albicansFlu1-MediatedEfflux of SalivaryHistatin 5 ReducesIts CytosolicConcentration and

custompeptide

Hst 5 and N-terminally biotin-labeledHst 5 (BHst 5) weresynthesized by Genemed SynthesisInc. (San Antonio, TX).

2013Raychaudhuri P

Mol. CancerTher; 12: 759 -767

Targeting FoxM1Effectively Retardsp53-NullLymphoma andSarcoma

custompeptide

Both wild-type ARF26–44(rrrrrrrrrKFVRSRRPRTASCALAFVN)and mutant ARF37–44(rrrrrrrrrSCALAFVN)peptides were synthesized byGenemed Synthesis Inc.The N-terminus of each peptide wasmodified with 9 DArg(r) residues.

2013 Bevan MJPNAS; 110: 6055- 6060

A T-cell responseto a liver-stagePlasmodiumantigen is notboosted byrepeated sporozoiteimmunizations

custompeptide

Erythrocyte-depleted cellsuspensions were madefromspleens or livers of euthanizedanimals on the days indicated inthe text. Antigens were added to 96-well enzyme-linked immunosorbentspot (ELISPOT) plates by usingeither individual peptides(1 × 10−10

2013DeBose-Boyd RA

J. Lipid Res; 54:1011 - 1022

Lipid-regulateddegradation ofHMG-CoAreductase and Insig-1 through distinctmechanisms ininsect cells

custompeptide

Following extensive washes in lysisbuffer containing 0.1% digitonin,bound proteins were eluted byrotating the beads with apeptide containing 5 copies of theFLAG epitope (custom synthesizedby Genemed Synthesis).

2013 Miljković D

J.Neuroimmunology; 259: 55–65

Saquinavir-NOinhibits S6 kinaseactivity, impairssecretion of theencephalytogeniccytokinesinterleukin-17 andinterferon-gammaand amelioratesexperimentalautoimmune

custompeptide

C57BL/6 mice were immunized bysubcutaneous injections into theleft flank of 0.2 ml of an emulsioncomposed of 200 μg MOG(35–55)(Genemed Synthesis, SanFrancisco, CA) in incompleteFreund's adjuvant(IFA, Difco) containing 1 mgMycobacterium tuberculosi

2013Palomares-Jerez MF

Biochimica etBiophysicaActa;1828:1938–1952

N-Terminal AH2segment of proteinNS4B fromhepatitis C virus.Binding to andinteraction withmodelbiomembranes

custompeptide

Peptides NS4BAH2 with sequenceKLEVFWAKHMWNFISGIQYLA (res-115 idues 45 to 65, HCV strain1a_H77 NS4B numbering),NS4BAH2-His with116 sequenceKLEVFWAKHMWNFISGIQYLAGHHHHHHG and NS4BSCAH2-His117 with sequenceVNFQFMAISGHEWKLYLAKIWGHHHHHHG, were syn-118

2013 Eini AAnaerobe; 22:20-24

Oxygen deprivationaffects theantimicrobial actionof LL-37 asdetermined bymicroplate real-timekineticmeasurementsunder anaerobic

custompeptide

LL-37(LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES), purifiedby HPLC (greater than 90%determined by Mass Spectrometry)waspurchased from GenemedSynthesis Inc., (San Antonio,TX).

2013 Guilliams T in press

Nanobodies Raisedagainst Monomericα-SynucleinDistinguishbetween Fibrils atDifferent MaturationStages

custompeptide

Similar experimentswere performed with the series ofsynthetic peptides(Genemed Synthesis Inc., SanAntonio, TX, USA)designed to span different stretchesof the αSyn sequencein the C-terminal region.

2013 Engel ALImmunobiology;218:1468–1476

Protein-boundpolysaccharideactivates dendriticcells and enhancesOVA-specific T cellresponse asvaccine adjuvant

custompeptide

Splenocytes orpooled dLN cells (2x105 cells/well)were added to the plates andstimulated with 10μg/mL OVAp323-339 (Anaspec) oran irrelevant peptide (tetanus toxoidor HepBpeptide, Genemed Synthesis) of thesame concentration.

2013LeskowitzRM

J. Virol; 87: 8351-8362

CD4+ and CD8+ T-Cell Responses toLatent AntigenEBNA-1 and LyticAntigen BZLF-1during PersistentLymphocryptovirusInfection of RhesusMacaques

custompeptide

The rhEBNA-1 peptide pool consistsof 85 15-merpeptides overlapping by 10 aminoacids except for the GA repeatdomain,which overlaps by 5 amino acids(Genemed Synthesis, Inc., SanAntonio,TX; NeoBioSci, Cambridge, MA)

2013Cramer-Morales K

Blood; 122: 1293- 1304

Personalizedsynthetic lethalityinduced bytargeting RAD52 inleukemias identifiedby gene mutationand expressionprofile

custompeptide

F79 synthetic peptide (aptamer)containing a sequence of 13 aminoacidssurrounding RAD52(F79)(VINLANEMFGYNG-GGG-YARAAARQARA)and the aptamer with F79A aminoacid substitution were purchasedfromGenemed Synthesis

2013Kouchkovsky D

J. Immunol; 191:1594 - 1605

microRNA-17–92Regulates IL-10Production byRegulatory T Cellsand Control of

custompeptide

oligodendrocyte glycoprotein(MOG)35–55 peptide (GenemedSynthesis)

2013 Pham D

J. Biol. Chem;288: 27423 -27433

The TranscriptionFactor Twist1Limits T Helper 17and T FollicularHelper CellDevelopment byRepressing the

custompeptide

oligodendrocyte glycoprotein(MOG)35–55 peptide (GenemedSynthesis)

2013 Sol AInfect. Immun;81: 3577 - 3585

LL-37 Opsonizesand Inhibits BiofilmFormation ofAggregatibacteractinomycetemcomitans atSubbactericidalConcentrations

custompeptide

LL-37(LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES), tetramethylrhodamine-labeledLL-37 (TMR-LL-37), scrambledLL-37 (sLL-37)(GLKLRFEFSKIKGEFLKTPEVRFRDIKLKDNRISVQR),and 6-carboxyfluorescein (6-FAM)-labeled scrambled LL-37 werepurchasedfrom Genemed Synthesi

2013NicoleMessmer M

J. Immunol; 191:4456 - 4465

Identification of theCellular Sentinelsfor NativeImmunogenic Heat

custompeptide

2013 Johnson CAInfect. Immun;81: 4139 - 4148

Cellular Responseto Trypanosomacruzi InfectionInduces Secretionof Defensin α-1,Which Damagesthe Flagellum,NeutralizesTrypanosomeMotility, and InhibitsInfection

custompeptide

Mature human defensin -1(ACYCRIPACIAGERRYGTCIYQGRLWAFCC) (31, 32) wassynthesized and highly purified byreverse-phase high-performance liquidchromatography (HPLC), resultingin a single sharp chromatographicpeak with approximately 98% purity(see F

2013 Pauken KEJ. Immunol; 191:4913 - 4917

Type 1 DiabetesOccurs despiteRobust AnergyamongEndogenous Insulin-

custompeptide

p31 peptide (YVRPLWVRME)(Genemed Sythesis)

2013 Silveira LVEJ. Virol; 87:13904 - 13910

TherapeuticVaccination againstthe RhesusLymphocryptovirusEBNA-1Homologue,rhEBNA-1, Elicits TCell Responses toNovel Epitopes inRhesus Macaques

custompeptide

RhEBNA-1-specific T cell epitopeswere identified from peripheralblood mononuclear cells (PBMCs)collected pre- andpostimmunization by first pulsingcells with a peptide libraryspanning rhEBNA-1 (GeneMedSynthesis; 15-mer peptidesoverlapping by 5 amin

2013Martínez-Llordella M

J. Exp. Med;210: 1603 - 1619

CD28-inducibletranscription factorDEC1 is requiredfor efficientautoreactive CD4+

custompeptide MOG 35-55

2013 Pham DJ. Immunol; 191:902 - 911.

Opposing Roles ofSTAT4 andDnmt3a in Th1

custompeptide MOG 35-55

2013 yang KJ. Virol; 87: 6876- 6887.

A Herpes SimplexVirus ScaffoldPeptide That Bindsthe Portal VertexInhibits Early Stepsin Viral Replication

custompeptide

Peptides with sequences ofRQIKIWFQNRRMKWKKYPYYPGEARGAP (wild type,designated peptide 1) orRQIKIWFQNRRMKWKKYPYAAGEARGAP(mutant, designated peptide 2) orbiotinlabeledversions of these peptides werecommercially synthesized with95% purity (Genemed S

2013ChouguleNP

PNAS; 110: 8465- 8470.

Retargeting of theBacillusthuringiensis toxinCyt2Aa againsthemipteran insectpests

custompeptide

A double-derivatized GBP3.1 peptidewith biotin at the N terminus and aUV-cross-linker attachedphenylalanine(Bpa; pbenzoyl-L- phenylalanine) inplace of the tyrosine (Y) within the 8-aaloop (Fig. 1A) was synthesized byGenemed Synthesis.

2013 Chen JXMacromol.Biosci; 13, 84–92

Self-AssembledBolA-likeAmphiphilicPeptides as Viral-Mimetic GeneVectors for CancerCell Targeted GeneDelivery

custompeptide

All peptides, RGD-ADDA-R8 (P1),RGD-AHX-R8 (P2), RGD-R8 (P3)andR8 (P4) were designed andsynthesized manually employing astandard solid phase syntheticmethod based on Fmoc chemistry.

2013 Katyal P

PROTEINSCIENCE;22:1358-1365

Structural insightsinto the recognitionof β3 integrincytoplasmic tail bythe SH3 domain ofSrc kinase

custompeptide

b3 heptapeptide (NITYRGT762),mono (ATSTFTNITpYRGT762), and bi-phosphorylated(RAKWDTANNPLpYKEATSTFTNITpYRGT762)C-termini of b3(MPCb3 and BPb3 respectively)were synthesizedchemically (Genemed Synthesis;NEO-peptides).

2013 Hsu YH

Mol & CellEndocrinology;381:168–174

Urotensin II exertsantiapoptotic effecton NRK-52E cellsthroughprostacyclin-mediatedperoxisome

custompeptide

Urantide(Asp-Pen-Phe-DTrp-Orn-Tyr-Cys-Val) was synthesized by GenemedSynthesis (San Antonio, TX, USA).

2013

Bailey-BucktroutSL

Immunity;39:949–962

Self-antigen-DrivenActivation InducesInstability ofRegulatory T Cellsduring an

custompeptide

MOG35-55 peptide(MEVGWYRSPFSRVVHLYRNGK,Genemed Synthesis)

2013RobinsonAP

J. Autoimmunity;43: 32-43

High-mobility groupbox 1 protein(HMGB1)neutralizationamelioratesexperimentalautoimmuneencephalomyelitis

custompeptide

All synthetic peptides were obtainedfrom Genemed Synthesis(San Francisco, CA)includingMBP84e104(VHFFKNIVTPRTPPPSQGKGR,>95.09% purity),MOG35e55(MEVGWYRSPFSRVVHLYRNGK,>98.16%),OVA323e339(ISQAVHAAHAEINEAGR,>98.69%), PLP139e151 (HSLGKWLGHPDKF, >97.1

2013 Saksida T

J.Neuroimmunology; 262: 72–78

Apotransferrininhibits interleukin-2expression andprotects mice fromexperimentalautoimmune

custompeptide

Proteolipid protein(PLP) (139–151) was synthesizedby Genemed Synthesis (SanFrancisco, CA, USA).

2013 An X

J. Biol. Chem;288: 11407 -11415

Impaired IntestinalCalcium Absorptionin Protein 4.1R-deficient Mice Dueto AlteredExpression of

Customproteinantibodies

Anti-PMCA1bantibodies were raised in rabbits atGenemed Synthesis Inc.

2013 Chang MCJ Periodont Res2013; 48: 66–73

Butyrate inducesreactive oxygenspecies productionand affects cellcycle progression in dna

PCR primers weresynthesized by GenemedBiotechnologies,Inc. (San Francisco, CA, USA)

2013 Gujar ADNeuropeptides;47: 139–147

Hypoglycemiadifferentiallyregulateshypothalamicglucoregulatoryneurotransmittergene and proteinexpression: Role ofcaudal dorsomedialhindbraincatecholaminergicinput dna

PCR primers for NPY (forward:50-ATGCTAGGTAACAAAC-G-30;reverse: 50-ATGTAGTGTCGCAGAG-3), prepro-orexin (forward: 50-CATATCCCTGCCCTGGT-C-30; reverse: 50-GATAGAAGACGGGTTCAGAC-30)and OT (forward: 50-GCACTGGCTGTTACTT-CTTC-3;reverse: 50-GCTTTGGGCTTTGGGTTA

2013 Carstens EJ Neurophysiol:109: 742 - 748.

Roles forsubstance P andgastrin-releasingpeptide asneurotransmitters Miscl

BAM8-22 (50 nmol; GenemedSynthesis, SanAntonio, TX).

2013 Ahmed GMJ. Endodontics;39: 444-448

Expression Levelsof MatrixMetalloproteinase-9and Gram-negativeBacteria inSymptomatic andAsymptomaticPeriapical Lesions Miscl

ThePower-Stain 1.0 Poly HRP DAB[3,30-diaminobenzidine] Kit (Cat# 54-0017; Genemed Biotechnologies,San Francisco, CA) was used tovisualizeany antigen-antibody reaction in thetissues.

2013 Jia YAndrology; 1,651–659

The cytoprotectivepeptide humanin isinduced andneutralizes Baxafter pro-apoptotic Miscl

HN (n = 4): daily IT injectionof 50 mcg HN (GeneMed Synthesis,Inc., San Antonio, TX, USA)

2013 Yuan Y

J.Ethnopharmacology; 149: 701–706

Sceptridiumternatum extractexertsantiasthmaticeffects byregulating Th1/Th2balance and the Miscl

DNAMakerI(GenemedSynthesis,USA)wasusedasacontrol.

2013JaykumarJC

ScientiaHorticulturae:161: 134–142

High multiplicationfrequency andgenetic stabilityanalysis ofCeropegiapanchganiensis, athreatened Miscl

total of 64 RAPD primers (GenemedSynthesis Inc, TX, USA)

2014 Li Y

NeuroscienceLetters 564:15–119

Ubiquitin C-terminalhydrolase L1interacts withcholine transporter


rabbit-anti CHT antibody (a customantibody

2014 Feng Q

Stem CellReports; 3:817–831

ScalableGeneration ofUniversal Plateletsfrom HumanInduced Pluripotent


For microtubule components,samples were stained with an anti-b1-tubulin antibody

2014 Sanchez SR

Biochimica etBiophysica Acta1843: 985–1001

Nucleocytoplasmicshuttling of theDuchennemuscular dystrophygeneproduct dystrophinDp71d isdependent on theimportin α/β and


primary antibodies were used:+78Dp71

2014 Cuddy LKJ. of neurochem;128, 5: 725–740

Regulation of thehigh-affinity cholinetransporter activityand trafficking by itsassociation withcholesterol-rich lipidrafts


Polyclonal CHT antibodywas raisedin rabbits to the antigenic peptideDVDSSPEGSG-TEDNLQ that isconserved at the carboxyl terminusof human andrat CHT, thispeptidewas conjugated to keyholelimpet hemocyanin carrier protein byan amino-terminal cysteine.

2014 Verma GMalaria Journal;13:475

The dimerizationdomain of PfCENP-C is requiredfor its functions asa centromereprotein inhuman malariaparasite


The peptide sequence N-VEVILVEKKLKKKKQKC-Cwas used to generate PfCENP-Cpolyclonal antibodies inmice followed by affinity purificationwith the respectivepeptide

2014 Voronin NRetrovirology;11:60

The dUTPase-related gene ofbovineimmunodeficiencyvirus is critical forviralreplication, despitethe lack of dUTPaseactivity of theencoded protein


The antipeptideantibodies were prepared in rabbitsagainst syntheticpeptides derived from the BIVdUTPase, RT and INproteins. All peptides and theantisera were preparedby Genemed Synthesis. ThedUTPase-derived peptidehas the sequenceCDSELQLQLLNIGTE

2014 Ruete MC

CellCommunicationand Signaling;12:43

Epac, Rap andRab3 act in concertto mobilizecalcium fromsperm’s acrosomeduring exocytosis


The rabbit polyclonal antibodiesagainst Epac were generatedby Genemed Synthesis, Inc. (SanFrancisco, CA)using the synthetic peptideLREDNCHFLRVDK, and affinitypurified on immobilized Epac peptide

2014 Zhang XBMC CellBiology; 15:32

Overexpression ofp49/STRAP alterscellularcytoskeletalstructure and grossanatomy in mice


we generated ap49/STRAP antibody against apeptide (KSKKGTEDALLKNQRRAQ) of the p49/STRAPprotein, which showedhigh specificity to the p49/STRAPprotein [1]. In thepresent study, the polyclonalantibody was commerciallypurified using affinity chromato

2014 Zhang HYPNAS; E5007-E5015

Cannabinoid CB2receptors modulatemidbraindopamine neuronalactivity anddopamine-relatedbehavior in mice


NIH5633 mCB2-Ab (custom-designed), which recognizesthe mCB2 receptor C-terminal. Theepitope (326-340 aa)is identical between rCB2 andmCB2 receptors.

2014 Nandi NJ. Cell Biol; 207:253-268

Acinus integratesAKT1 andsubapoptoticcaspase activitiesto regulate basal


Acn-pS641 antibody was raised inrabbits against theRSRSGS(p)PASKTKKC peptideand double affinity purified

2014 Maeda RPNAS;111:12907-12912

Tip-link proteinprotocadherin 15interacts withtransmembranechannel-likeproteins TMC1 andTMC2


Antibodies for TMC1and TMC2 were made (byGenemed Synthesis) by injectingrabbits with mouse TMC peptides[TMC1: KLPRRESLRPKRKRTR[C](residues 24–39),[C]DEETRKAREKERRRRLRRG(residues 53–71),CKPWKMEKKIEVLKEAKKF(residues 102–120), and [C]NATAKGQKAANLDL

2014 Gregorio SF

J. Exp. Biol., May2014; 217: 1555 - 1562

Endocrineregulation ofcarbonateprecipitateformation in marine

customantipeptideantibodies STC antibody

2014 Ma J

Am J PhysiolHeart CircPhysiol; 306:H233 - H242

Structural andfunctional analysisof the relatedtranscriptionalenhancer factor-1and NF-{kappa}B


The membranes were incubatedwith the indicated primaryantibodies: polyclonal anti-RTEF-1antibody(1:10,000 dilution)

2014 Fan YJ. Exp. Med;211: 313 - 328

USP21 negativelyregulates antiviralresponse by actingas a RIG-Ideubiquitinase


Anti-USP21 antibodies weregenerated by immunizing rabbitswith thesynthetic peptides corresponding toamino acidsMPQASEHRLGRTREPP,RLALRPEPPTLRRSTSLR,NAPVCDRCRQKTRSTKKLTV)

2014 Chung JJ. Biol. Chem;289: 7835 - 7843

Iron RegulatoryProtein-1 Protectsagainst Mitoferrin-1-deficient Porphyria


Custom, affinity-purified anti-mouseMFRN1 rabbit polyclonal antibodywas generated using the followingpeptide: C-HESHVQEVSHKTSPT

2014 Ren A

J. Biol. Chem;289: 35757 -35769

AsymmetricalMacromolecularComplex Formationof LysophosphatidicAcid Receptor 2(LPA2) Mediates


Anti-LPA 2 antibody (rabbit 2143)and anti-NHERF2 antibody (rabbit2346) were generated

2014 Albers S

Neurobiology ofDisease; 69:32–42

Nuclear 82-kDacholineacetyltransferasedecreasesamyloidogenic APPmetabolism in


antibodies in rabbits to peptideCEKATRPSQGHQP at the carboxyl-terminus of human ChAT thatrecognizesboth 69- and 82-kDa enzymes

2014 Soo Park MCell Tissue Res;356:405–416

Cloning of PaAtg8and roles ofautophagy inadaptation tostarvation withrespect to the fatbody and midgut of


Polyclonal rabbit anti-PaAtg8antibody for immunoblottingwas generated against a peptidesequence(FEKRKAEGEKIRRKYPDR)

2014MartynovaaEU

MolecularBiology; 48:301–304

Intracellularlocalization ofregulatory proteinsof the Germancockroach Blattella


epitopes in BgDNV NS1, NS2, andNS3 proteins.

2014 Binzer M

The Journal ofComparativeNeurology;522:337–357

Neuropeptidome ofTriboliumcastaneumAntennal

customantipeptideantibodies Custom antipeptide antibodies

2014 Wu KLH

Journal ofBiomedicalScience; 21:8

An increase inadenosine-5’-triphosphate (ATP)content in rostralventrolateralmedulla isengaged in the highfructose diet-inducedhypertension

customdna

The primer pairs for amplificationof KHK cDNA are: forward (5′-GATACCCCTTGCTCTTGCTG-3′) and reverse (5′-TGCAGCATCTTCACCTGTTC-3′); β-actin cDNA are: forward(5′- GCTGAGAGGGAAATCGT −3′) and reverse (5′-CGTCAGGCAGCTCATAG −3′).

2014 Gujar AD

Am J PhysiolRegulatoryIntegrative CompPhysiol; 306:R457-R469

HindbrainlactostasisregulateshypothalamicAMPK activity andmetabolicneurotransmittermRNA and proteinresponses tohypoglycemia

customDNA

PCR primers for NPY (forward: 5=-ATGC-TAGGTAACAAACG-3=;reverse: 5=-ATGTAGTGTCGCAGAG-3), prepro-orexin(forward: 5=-CATA-TCCCTGCCCTGGTC-3=; reverse:5=-GATAGAAGACGGGTTCAGAC-3=),and OT (forward: 5=-GCA-CTGGCTGTTACTTCTTC-3;reverse: 5=-GCTTTGGGCTTTGGGTTAG

2014 Chang HH

ActaBiomaterialia;10: 722–731

Urethanedimethacrylateinduces cytotoxicityand regulatescyclooxygenase-2,hemeoxygenaseand

customDNA custom primers

2014 Chavan JJPlant GrowthRegul; 72:1–15

Efficiency of directand indirect shootorganogenesis,molecular profiling,secondarymetaboliteproduction and

customDNA f 45 random decamer primers

2014 Jacobs ESRetrovirology;11:57

A CD4+ T cellantagonist epitopedown-regulatesactivating signalingproteins, up-regulatesinhibitory signalingproteins and

custompeptide

The 16 amino acid agonist peptidePP16 (PEVIPMFSALSEGATP)and 13 amino acid antagonistpeptidePG13 (PEVIPMFSALSEG) wereobtained

2014 Melera CPNAS; 111, 43:15426-15431

Quantification ofthe transferability ofa designedprotein specificityswitch revealsextensive epistasis

custompeptide

Fluorescein-labeled peptideswere synthesized to PDZ domain

2014 Sant'Anna R

J. Biol. Chem;289: 28324 -28337

The Importance ofa GatekeeperResidue on theAggregation ofTransthyretin:IMPLICATIONSFORTRANSTHYRETIN-RELATEDAMYLOIDOSES

custompeptide

Theintrinsic aggregation and amyloidformation propensities wereevaluated for the wild type TTRsequence and the K35L andK48L variants, either in the contextof the complete proteinsequence or considering theisolated TTR 26–57-derivedpeptides.

2014Varrin-doyer M

NeurolNeuroimmunolNeuroinflammation; 1: e20

MOGtransmembraneand cytoplasmicdomains containhighly stimulatory T-cell epitopes in MS

custompeptide

Human MOG p119-130(FYWVSPGVLVLL),MOG p181-195(TLFVIVPVLGPLVAL), and p186-200(VPVLGPLVALIICYN) weresynthesized.

2014 Veomett N

Clin. CancerRes; 20: 4036-4046

TherapeuticEfficacy of an Fc-Enhanced TCR-likeAntibody to the

custompeptide

Peptides for T2 pulsing assays werepurchased

2014 Shetty A

NeurolNeuroimmunolNeuroinflammation; 1: e22

Immunodominant T-cell epitopes ofMOG reside in itstransmembraneand cytoplasmicdomains in EAE

custompeptide

Overlapping synthetic MOGpeptides spanning the entire218 aa sequence of mouse MOGand associated truncated peptideswere synthesized

2014 Flynn RJ. Biol. Chem;289:16675-16687

Targeting theTransient ReceptorPotential VanilloidType 1 (TRPV1)Assembly DomainAttenuatesInflammation-inducedHypersensitivity

custompeptide

N-terminally palmitoylatedpeptides were obtained fromGenemed Synthesis (SanAntonio, TX) with at least 90% puritywith the followingsequences: TRPV1, 734–752,KDDYRWCFRVDEVNWTTW;scrambled,TTWVDEWNFCRWDYRDKV.

2014 Cai QJ. Biol. Chem;289:16046-16056

α-N-Methylation ofDamaged DNA-binding Protein 2(DDB2) and ItsFunction in

custompeptide

syntheticN-terminal peptide of DDB2

2014 Avogadri FCancer Immunol.Res; 2: 448 - 458

Combination ofAlphavirus RepliconParticle–BasedVaccination withImmunomodulatoryAntibodies:Therapeutic Activityin the B16

custompeptide

TRP2181–189or OVA257–264 (SIINFEKL) peptide(>80% purity)

2014 Leskowitz RJ. Virol; 88: 4721- 4735

Adenovirus-BasedVaccines againstRhesusLymphocryptovirusEBNA-1 InduceExpansion ofSpecific CD8+ andCD4+ T Cells in

custompeptide

rhEBNA1 peptide pool consists of85 15-mer peptides overlapping by 10amino acids except for the GArdomain,where peptides overlap by 5 aminoacids

2014 Tkach KEeLife Sci; 3:e01944

T cells translateindividual, quantalactivation intocollective, analogcytokineresponses via time-integrated

custompeptide

TRP-1 peptide(sequence:SGHNCGTCRPGWRGAACNQKILTVR) was obtained

2014 Vieira TFASEB J; 28:2667 - 2676

Heparin bindingconfers prionstability and impairsits aggregation

custompeptide

Syrian hamster PrP109–149(ShaPrP109–149) peptide

2014 Tati S


Histatin 5-SpermidineConjugates HaveEnhancedFungicidal Activityand Efficacy as aTopical Therapeuticfor Oral Candidiasis

custompeptide

Hst 54 –15 peptides conjugated withspermidine (Spd-Hst 54 –15 and Hst54 –15-Spd) were synthesized using9-fluorenylmethoxy carbonyl(Fmoc) chemistry and N, N-di-cyclohexylcarbodiimide couplingreagent.

2014 Vargas JYJ. Neurosci; 34:2191 - 2202

In vivo Activation ofWnt SignalingPathway EnhancesCognitive Functionof Adult Mice andReverses Cognitive

custompeptide

FOXY-5 (Formyl-MDGCEL) wasobtained

2014 Zhang LPNAS; 111: 2656- 2661

Monoclonalantibody blockingthe recognition ofan insulinpeptide–MHCcomplex modulatestype 1 diabetes

custompeptide

-Ag7 Insulin (B:9–23) NaturalSHLVEALYLVCGERG SolubleI-Ag7 Insulin (B:9–23) R1:REHLREALYLVCEERG LinkedI-Ag7 Insulin (B:9–23) R2:REHLVRALYLVCGERG LinkedI-Ag7 Insulin (B:9–23) R3:REHLVERLYLVCGEEG BothI-Ag7 Insulin (B:9–23) R3:REssHLVERLYLVCGEEG-α62†

2014 Berkley AMJ. Immunol; 193:3262 - 3266

Cutting Edge:CD8+ RecentThymic EmigrantsExhibit IncreasedResponses to Low-Affinity Ligands andImproved Access to

custompeptide

SIIQFEKL (Q4; a potency of 1/18),and SIITFEKL (T4; a potency of1/71) were obtained


J. Biol. Chem;289: 25166 -25176

Binding of Tissue-type PlasminogenActivator to theGlucose-regulatedProtein 78 (GRP78)ModulatesPlasminogenActivation and

custompeptide

Leu 98 -Leu 115 K113V ) andscrambledGTNKSQDLWIPQLRDVFI (Leu 98 -Leu 115 scrm ) peptides wereobtained

2014 Sol A

J. Biol. Chem;289: 22926 -22941

Actin Enables theAntimicrobial Actionof LL-37 Peptide inthe Presence ofMicrobial Proteases

custompeptide

LLGDFFRKSKEKIGKEFKRSVQRSKDFLRNLVPRTE, andtetramethylrhodamine-labeled LL-37(r-LL-37) were purchased

2014 Sheats MK

VeterinaryImmunology andImmunopathology; 160 :167–176

MyristoylatedAlanine Rich CKinase Substrate(MARCKS) isessential to β2-integrin dependentresponses ofequine neutrophils

custompeptide

MANS and RNS peptides, aspreviously described, weresynthesized by Genemed Synthesis,Inc. (San Francisco, CA,USA)(Singer et al., 2004). Thesequence ofMANS is identicalto the first 24 amino acids of thehuman MARCKS protein:myristic acid-GAQFSKTAAKGE

2014 Chang YCStructure; 22:1810–1820

Structural andMechanisticInsights into theRecruitment ofTalin by RIAM in

custompeptide

The RIAM peptide consisting ofresidues 5–25

2014 Aydintug MK

MolecularImmunology; 60:116–128

γδ T cells recognizethe insulin B:9–23peptide antigenwhen it is dimerizedthrough thiol

custompeptide

B:9–23 insulin peptide and modifiedforms of this peptide(B:16A and B:19A) were synthesized

2014 Gil EY

Breast CancerRes Treat;147:69–80

Vaccination withErbB-2 peptidesprevents cancerstem cellexpansion andsuppresses thedevelopment ofspontaneous tumorsin MMTV-PyMTtransgenic mice

custompeptide

Two 15-mersof MHC class II ErbB-2 peptideswere used for the immunizationof ErbB-2 group: p101 peptide(RLRIVRGQLFEDKYAL)and p373 peptide(KIFGSLAFLPESFDGDPS).As a peptide control, a 15-mer pan-HLA-DR binding peptidefrom tetanus toxoid p2 (830–844) p

2014 Chaves APJ

J Biol InorgChem;19:839–851

Biophysical andmorphologicalstudies on the dualinteractionof non-octarepeatprion proteinpeptides with

custompeptide

PrP109–149 peptide, with sequence109-MKHMAGAAAAGAVVGGLGGWMLGSAMSRPMMHFGNDWEDRY-149

2014 Fidai I

J Biol InorgChem;19:1327–1339

Inactivation ofsortase A mediatedby metal ATCUNcomplexes

custompeptide

Selected peptides, GGHLPETG-NH2,GGHLPET-NH2, GGHGLPETG-NH2 and GGHGLPETNH2,were custom synthesized

2014 Disis ML

Cancer ImmunolImmunothe;63:101–109

HER

‑2/neu

vaccine

‑primed

autologous T

‑cell

infusionsfor the treatment ofadvanced stageHER

‑2/neu

expressingcancers

custompeptide

In brief, PBMC were stimulated witha peptidepool of three HER2 MHC class IIepitopes (GenemedSynthesis Inc) to which the patienthad generated the greatestmagnitude cellular immuneresponse after the vaccination(10 ug/ml each peptide)

2014 Munoz A

MolecularMicrobiology;92(6): 1357–1374

Specific domains ofplant defensinsdifferentially disruptcolony initiation, cellfusion and calciumhomeostasis in

custompeptide

Tetramethyl rhodamine-labelled andunlabelled peptidesderived from defensins weresynthesized

2014 Shi JFASEB J; 28:244 - 255

Myristoylatedalanine-rich Ckinase substratecoordinates nativeTRPC1 channelactivation byphosphatidylinositol4,5-bisphosphate

custompeptide

MANS peptide (Myr-GAQFSKTAAKGEAAAERPGEAAVA)and RNS peptide (MYr-GTAPAAEGAGAEVKRASAEAKQAF)were synthesized

2014 Farooq SM

Brain, Behavior,and Immunity;35: 64–69

In vitro-induced cell-mediated immunedeviation toencephalitogenicantigens

custompeptide

The antigens used were MOG35–55(Genemed Synthesis Inc., SanAntonio, Texas, USA)

2014García-Caballero A

Neuron; 83:1144–1158

TheDeubiquitinatingEnzyme USP5ModulatesNeuropathic andInflammatory Painby EnhancingCav3.2 ChannelActivity

custompeptide

human biotin-Cav3.21556–1602,biotin-Cav3.21569–1586, scrambledbiotinCav3.21556–1602-III-IVlinker, biotin-Cav3.21860–1884-CT,Tat-Cav3.21569–1589-IIIIV,no-Tat Cav3.21569–1589-III-IV, Tat-Cav3.2-CT1860–1884, no-Tat-Cav3.2-CT1860–1884 peptides

2014 Kang YKMol. Cell. Biol;34: 1670 - 1681

E2/EstrogenReceptor/SjogrenSyndrome-AssociatedAutoantigenRelievesCoactivatorActivator-Induced

customproteinantibodies

The polyclonal anti-CoAA wasgenerated in rabbits by immunizationwith a glutathione S-transferase(GST)–CoAA C-terminalfragment (amino acid residues 580to 669) fusion protein

2014 Zhang J

Histochem CellBiol; 142:529–539

Comprehensivecharacterization ofprotein 4.1expression in


Different 4.1 antibodies weregenerated in rabbits

2014 Stumpf MEur. J. Immunol;44: 1737–1746

Tyrosine 201 of thecytoplasmic tail ofCTLA-4 criticallyaffects T regulatorycell suppressive Miscl MOG35–55 peptide

2014 Eitas TKJ. Biol. Chem;289: 4173 - 4179

The Nucleotide-binding Leucine-rich Repeat (NLR)Family MemberNLRX1 MediatesProtection againstExperimentalAutoimmuneEncephalomyelitis Miscl MOG 35-55 peptide

2014AlessiWolken DM

Mol. Biol. Cell;25: 753 - 762

Aim44p regulatesphosphorylation ofHof1p to promotecontractile ringclosure duringcytokinesis in Miscl

To induce cell-cycle arrest in G1phase, wetreated mid-log-phase cultures with10 μMα-factor

2014 Yu JJ. Immunol; 193:422 - 430

T Cell–IntrinsicFunction of theNoncanonical NF-{kappa}B Pathwayin the Regulation ofGM-CSFExpression and Miscl MOG 35-55

2014Glosson-Byers NL

J. Immunol; 193:2631 - 2640

Th17 CellsDemonstrateStable CytokineProduction in a Miscl MOG 35-55

2014 Fazio FNeuropharmacology; 81: 237e243

Cinnabarinic acid,an endogenousagonist of type-4metabotropicglutamate receptor,suppressesexperimental Miscl MOG 35-55

2014 Blink SE

CellularImmunology 290(2014) 39–51

γδ T cell subsetsplay opposing rolesin regulatingexperimentalautoimmuneencephalomyelitis Miscl

PLP139–151(HSLGKWLGHPDKF) andMOG35–55(MEVGWYRSPFSRVVHLYRNGK),were purchased

2014 Thome RImmunology;143: 164–173

Dendritic cellstreated with crudePlasmodiumberghei extractsacquire immune-modulatoryproperties and Miscl MOG35-55

2014 Mangano K

J. CELLULARPHYSIOLOGY;229: 1918–1925

HypomethylatingAgent5-Aza-20-deoxycytidine(DAC) AmelioratesMultiple Sclerosis Miscl MOG35-55, PLP 139-151

2014 Hussien YGLIA; 62:680–691

Genetic inactivationof PERK signalingin mouseoligodendrocytes:Normaldevelopmentalmyelination with Miscl MOG35-55

2015AlmeidaJPM

In vivo GoldNanoparticleDelivery of PeptideVaccine InducesAnti-TumorImmune Response

2015Christianson DR

PNAS; 112: 2521- 2526

Ligand-directedtargeting oflymphatic vesselsuncoversmechanisticinsights inmelanomametastasis


The GLTFKSL peptide wassynthesized,conjugated to Keyhole limpethemocyanin, and used toimmunize New Zealand Whiterabbits for the generation ofpolyclonal Abs

2015 Yin W

J. Am. Soc.Nephrol;10.1681/ASN.2015050500

Mammalian Targetof RapamycinMediates KidneyInjury Molecule 1-Dependent TubuleInjury in aSurrogate Model


Antibodies were synthesized byGenemed Synthesis Inc. (SanAntonio, Texas). Western Blotanalysis...antibody #1) andLFLRLRRYREQTI (antibody #3)(1:500, Genemed Synthesis Inc.)

2015 Wu QFASEB J; 29:4989 - 5005

Talin1 is requiredfor cardiac Z-diskstabilization andendothelial integrity

customantipeptideantibodies Staining with anti-Itgbeta1b (1:200;)

2015 Wang LSciAdv; 1:e1500463

MED12 methylationby CARM1sensitizes humanbreast cancer cellsto chemotherapydrugs


eneration of methylated MED12 (me-MED12)-specific antibody Me-MED12-specific anti-peptideantibody was generated. The KLH(keyhole limpet hemocyanin)-conjugated MED12 peptideDPYRPVR(me2)LPMQKLPTRC,with R1862 asymmetricallydimethylated

2015 Kumar RInfect. Immun;83: 2614 - 2626

Novel AggregationProperties ofCandida albicansSecreted AspartylProteinase Sap6Mediate Virulencein Oral Candidiasis


polyclonal Cek1 antibody (raisedagainst two fragments of Cek1protein, from amino acids 86 to 101and 111 to 125, by GenemedSynthesis, Inc.). This Cek1 antibodyrecognizes Cek1p, as well as itsclose homologue Cek2p

2015 Grillon EBMC Res Notes;8:207

Spatial profilesof markersof glycolysis,mitochondria,and proton pumpsin a ratglioma suggestcoordinated


Antibody against a conservedpeptide of the E subunitof V-ATPase(SVSAEEEFNIEKLQLVEAEKKKIRQ)

2015 Kumar RInfect Immun;83:2614 –2626

Novel AggregationProperties ofCandida albicansSecreted AspartylProteinase Sap6Mediate Virulencein Oral Candidiasis


. Cek1 protein was used as aloading control and detected by apolyclonal Cek1 antibody (raisedagainst two fragments of Cek1protein, from amino acids 86 to 101and111 to 125, by Genemed Synthesis,Inc.). This Cek1 antibody recognizesCek1p, as well as

2015Christianson DR

PNAS; 112, 8:2521-2526

Ligand-directedtargeting oflymphatic vesselsuncoversmechanisticinsights inmelanomametastasis


The GLTFKSL peptide wassynthesized,conjugated to Keyhole limpethemocyanin, and used toimmunize New Zealand Whiterabbits for the generation ofpolyclonal Abs

2015 Yang XDPNAS; 112:E137 - E146

β-Catenin–relatedprotein WRM-1 is amultifunctionalregulatory subunitof the LIT-1 MAPK

customantipeptideantibodies LIT-1e antibodies

2015 Anekal PVJ. Biol. Chem;290: 2112 - 2125

Arg Kinase-bindingProtein 2 (ArgBP2)Interaction with α-Actinin and ActinStress Fibers


rabbit anti-ArgBP2 was raisedagainst residues 1?303

2015 Aguilar AFASEB J; 29:1842 - 1858

Nuclear localizationof the dystrophin-associated proteinα-dystrobrevinthrough importinα2/β1 is critical forinteraction with thenuclear


rabbit polyclonal anti-Dp71antibodies +78Dp71

2015 Li R


Candida albicansCek1 Mitogen-Activated ProteinKinase SignalingEnhancesFungicidal Activityof Salivary Histatin 5


polyclonal Cek1 antibody (raisedagainst two fragments of Cek1protein, from amino acids 86 to 101and 111 to 125). This Cek1 antibodyrecognizes Cek1p as well as itsclose homologue, Cek2p

2015 Kang SHVirology; 482:208–217

Membraneassociation of anonconserved viralproteinconfers virus abilityto extend its hostrange


Three regions of the p33 aasequence were selected forantipeptideantibody production (15–33 aa:KWFRRRTYHRKYFGDVVKD,185–199 aa: SVATDDVEDVKYIRK,and 264–280 aa:EYNENARSRVSLIRRVC)based on the hydrophilicity plot

2015 Cuddy LKJ. Neurochem;10.1111

Differentialregulation of thehigh-affinity cholinetransporter by wild-type and Swedishmutant amyloidprecursor protein


Polyclonal CHT antibody was raisedin rabbits to theantigenic peptideDVDSSPEGSGTEDNLQ,conserved at theC-terminus of human and rat CHT(Genemed Synthesis, SanAntonio, TX, USA); this peptide wasconjugated to KLH carrierprotein by an N-terminal cyste

2015 Hartnett SPhysiol Rep, 3(11). E12609

Reduced vagalcontrol of the heartin high-fat dietmice: a potentialrole of increased


rabbit anticholine transporter (CHT,a customantibody (Ferguson et al.2003)

2015 Kang SWVirology 482:208–217

Membraneassociation of anonconserved viralprotein confersvirus ability toextend its hostrange


Three regions of the p33 aasequence were selected forantipeptideantibody production (15–33 aa:KWFRRRTYHRKYFGDVVKD,185–199 aa: SVATDDVEDVKYIRK,and 264–280 aa:EYNENARSRVSLIRRVC)based on the hydrophilicity plot.Custom antibody productionusing rabbi

2015 Mikani ACell Tissue Res:362:481–496

Brain-midgut cross-talk and autocrinemetabolastat viathe sNPF/CCAPnegative feed-backloop in theAmericancockroach,Periplanetaamericana


C-terminal of putative cockroachsNPF inP. americana: Ala-Asn-Arg-Ser-Pro-Ser-Leu-Arg-Leu-ArgPhe(Veenstra and Lambrou 1995).Strong homology betweenthis peptide and other sNPF-likesequences has been identifiedin other insects (Mikani et al. 2012).We

2015KshirsagarPR

BiotechnologyReports; 6: 79–84

Highly efficient invitro regeneration,establishment ofcallus and cellsuspensioncultures and RAPDanalysis of

customDNA 30 random decamer primers

2015 Tamrakar P

Journal ofNeuroscienceResearch;93:321–332

Estrogen RegulatesEnergy MetabolicPathway andUpstreamAdenosine50-Monophosphate-Activated ProteinKinase andPhosphataseEnzymeExpression inDorsal VagalComplexMetabolosensoryNeurons During

customDNA

ERa(NM_012689) forward 50-AAGCACAAAGCGTAGAG-30,reverse 50-GGTTCAGCATCCAATAAGG-30; ERb (NM_012754) forward 50-AAAGCCAAGA-GAAACGGTGGGCAT-30, reverse 50-GCCAATCATGTGCACCAGTTCCT-30obtained

2015 Alenazi FSH

J. NeuroscienceResearch93:651–659

Estradiol RegulatesEffects ofHindbrain Activator5-Aminoimidazole-4-Carboxamide-RibosideAdministrationon HypothalamicAdenosine50-Monophosphate-Activated ProteinKinaseActivity andMetabolic

customDNA

CRH, forward 5-CAGCCGTTGAATTTCTTG-3,reverse 5-GACTTCT-GTTGAGGTTCC-3; POMC,forward 5-TCACCACGGAAAGCAACCTG-3,reverse5-TTTCAGT-CAAAGGCTGTTC-ATCTC-3; NPY,forward 5-ATGCTAGGTAACAAACG-3,reverse 5-ATGTA-GTGTCGCAGAG-3; SF-1,forward 5- GTACGGCAAGGAAGACAGC

2015 Tamrakar P

J. NeuroscienceResearch; 93:321–332

Estrogen regulatesenergy metabolicpathway andupstreamadenosine 5′-monophosphate-activated proteinkinase andphosphataseenzyme expressionin dorsal vagalcomplexmetabolosensoryneurons duringglucostasis andhypoglycemia

customDNA

ERa(NM_012689) forward 50-AAGCACAAAGCGTAGAG-30,reverse 50-GGTTCAGCATCCAATAAGG-30; ERb (NM_012754) forward 50-AAAGCCAAGA-GAAACGGTGGGCAT-30, reverse 50-GCCAATCATGTGCACCAGTTCCT-30obtained

2015 De Genst EJ. Mol Bio; 427:2166-2178

Structure of aSingle-Chain FvBound to the17 N-TerminalResidues ofHuntingtinProvides Insightsinto Pathogenic

custompeptide

Spectra of 15N-labeled C4scFv were recorded free or in thepresence of 1.2 molarequivalents of unlabeled HTT(1-17)peptide

2015 Hou Y

Stem cellresearch; 14:133-143

A critical role ofCXCR2 PDZ-mediatedinteractions inendothelialprogenitorcell homing andangiogenesis

custompeptide

he human and murineCXCR2 C-tail peptides (biotin-conjugate at N-terminus): WT(biotin-FVGSSSGHTSTTL forhuman CXCR2 C-tail; andBiotinFVSSSSANTSTTLfor mouse CXCR2 C-tail) and PDZmotifdeletion (ΔTTL) were synthesized byGenemed Synthesis,Inc. (San Ant

2015Sondergaard PC

Annals of ClinicalandTranslationalNeurology; 2(3):256–270

AAV.DysferlinOverlap VectorsRestore FunctioninDysferlinopathyAnimal Models

custompeptide

Three peptide pools wereusedwhich were used for the AAVrh.74capsid protein(Genemed Synthesis,San Antonio, TX) containing34–36peptides, each 18 aminoacids long and overlapping by11residues. Ten peptide pools wereused which encompassthe dysferlinpro

2015 Gadotti VMMolecular Pain;11:12

Small organicmolecule disruptorsof Cav3.2 - USP5interactions reverseinflammatory andneuropathic

custompeptide

biotinylated Cav3.2 III-IV linkerpeptide

2015NakayamaM

PNAS; 112, 14:4429-4434

Regulatory vs.inflammatorycytokine T-cellresponsesto mutated insulinpeptides in healthy

custompeptide

s. The insulin B:9–23 and mimotopepeptides

2015 Bhat P

Nucleic AcidsResearch; 43, 5:2888-2901

The beta hairpinstructure withinribosomal proteinS5mediates interplaybetween domains II

custompeptide

S5C2 and NSPS5 peptides werecustom synthesized

2015 Puri SJ. Dental Res;94: 201 - 208

Iron BindingModulatesCandidacidalProperties of

custompeptide

Flow Cytometry for Hst 5 BindingTo measure the binding of FITC-labeled Hst 5

2015 Nakagawa YJ. Immunol; 194:1274 - 1284

EndogenousIntracellularCathelicidinEnhances TLR9Activation in

custompeptide

Recombinant mouse CRAMP(mCRAMP) peptide was synthesized

2015 Quinn MJ. Immunol; 194:1726 - 1736

Memory T CellsSpecific for MurineCytomegalovirusRe-Emerge afterMultiple Challengesand RecapitulateImmunity in Various

custompeptide

2015 Kalokhe AS

J. InfectiousDisease; 211:635 - 640

ImpairedDegranulation andProliferativeCapacity ofMycobacteriumtuberculosis–Specific CD8+ T Cells in

custompeptide

stimulation with ESAT-6/CFP-10peptide pools of 15 mer overlappingwith 11 amino acids (10 microg/mL)

2015 Kauvar LM


A High-AffinityNative HumanAntibodyNeutralizes HumanCytomegalovirusInfection of DiverseCell Types

custompeptide

measurement of binding to (i) thepeptide with biotin and a hydrophilicPEG6 spacer attached to the N or Cterminus (Genemed Synthesis, SanAntonio, TX) at both high and lowdensity on neutravidin-derivatizedfluorescent latex beads

2015MorampudiV

Am J PhysiolGastrointestLiver Physiol;308: G389 -G402

Vasoactiveintestinal peptidepreventsPKC{varepsilon}-induced intestinalepithelial barrierdisruption during

custompeptide

Individual mice were treated withPKC inhibitor peptide (N-Myr-EAVSLKPT, 1,054 mol wt) in saline(2 mg/kg ip) 1 h prior to infection onday 0 and then daily to day 10postinfection.

2015 Boonyalai N

Molecular &BiochemicalParasitology;201: 5–15

PlasmodiumfalciparumPlasmepsin V(PfPMV): Insightsinto recombinantexpression,

custompeptide synthethic FRET peptides

2015 Lin CH

Sensors andActuators; B 211:7–16

Surfacecomposition andinteractions ofmobile charges withimmobilizedmolecules on

custompeptide

PSGL-1 peptide (ATEYEYLDYDFL)and sulfated peptidewere purchased

2015 Vargas JY

ExperimentalNeurology; 264:14–25

WASP-1, acanonical Wntsignalingpotentiator, rescueshippocampalsynaptic

custompeptide

Synthetic Aβ1–42peptide corresponding to the humanAβ wild-type peptide

2015 Ataie N in press

Structure of a TCR-Mimic Antibody withTarget PredictsPharmacogenetics

custompeptide

2015 Hou Y

Stem CellResearch: 14,133–143

A critical role ofCXCR2 PDZ-mediatedinteractions inendothelialprogenitor cellhoming andangiogenesis

custompeptide

The human and murineCXCR2 C-tail peptides (biotin-conjugate at N-terminus): WT(biotin-FVGSSSGHTSTTL forhuman CXCR2 C-tail; andBiotinFVSSSSANTSTTLfor mouse CXCR2 C-tail) and PDZmotifdeletion (ΔTTL)

2015 Lin CH

Sensors andActuators B 211:7–16

Surfacecomposition andinteractions ofmobile charges withimmobilized

custompeptide . PSGL-1 peptide (ATEYEYLDYDFL)

2015SappakhawK

Molecular &BiochemicalParasitology 204:51–63

Biochemicalcharacterization ofplasmepsin V fromPlasmodium vivaxThailand isolates:

custompeptide FRET peptides

2015 Ebben JD

MOLECULARCARCINOGENESIS: DOI:10.1002/mc.22405

Epidermal growthfactor receptorderived peptidevaccination toprevent lungadenocarcinomaformation: An in

custompeptide

Two peptides comprising residues306–325(SCVRACGADSYEMEEDGVRK) and residues897–915(VWSYGVTVWELMTFGSKPY) of human EGFR

2015NemetskiSM1 Malar J: 14:324

Inhibition bystabilization:targeting thePlasmodiumfalciparumaldolase–TRAPcomplex

custompeptide

Synthetic peptides derived from thecytoplasmic tailsof P. falciparum and P. bergheiTRAP were customsynthesizedby Genemed Synthesis, Inc (TX,USA).These included PfTRAP25(ETLGEEDKDLDEPEQFRLPEENEWN), PfTRAP6(EENEWN), PbTRAP25(VMADDEKGIVEDEGFKLPEDND

2015 Gadotti VMMolecular Pain.11:12

Small organicmolecule disruptorsof Cav3.2 - USP5interactions reverseinflammatory and

custompeptide

biotinylated Cav3.2 III-IV linkerpeptide

2015 Jiang G

Journal ofNeuroinflammation.12:179

HMGB1 releasetriggered by theinteraction of liveretinal cells anduveitogenic T cellsis Fas/FasLactivation-dependent

custompeptide

The 12-amino acid peptide, mouseMet 12 (HHIYLGAVNYIY),which is a small molecular weightinhibitorof the Fas [23, 24], and a mutantMet 12 (HHGSDHERNYIY)were synthesized

2015 Yang HJ. Exp. Med;212: 5 - 14

MD-2 is requiredfor disulfideHMGB1–dependentTLR4 signaling

custompeptide

eptides (FSSE, FSSEY, FEEE,FEED, SSE, and SFSE) and CBP(MKRRWKKNFIAVSAANRFKKISSSGAL) were all custom-made

2015 Bhat P

Nucleic AcidsRes; 43: 2888 -2901

The beta hairpinstructure withinribosomal proteinS5 mediatesinterplay betweendomains II and IV

custompeptide

pCD HCV 3 UTRconstruct was used to transcribeHCV 3 UTR RNA. S5M1,S5C2 and NSPS5 peptides werecustom synthesized f

2015NakayamaM

PNAS; 112: 4429- 4434

Regulatory vs.inflammatorycytokine T-cellresponses tomutated insulinpeptides in healthy

custompeptide

The insulin B:9–23 and mimotopepeptides

2015 Fife BTJ. Immunol; 194:3551 - 3555

Identification ofAutoreactive CD4+and CD8+ T CellSubsets Resistantto PD-1 Pathway

custompeptide

acetylated P31 (1040-31) peptide(YVRPLWVRME)

2015 Gong Z

Am J PhysiolEndocrinolMetab; 309:

Central effects ofhumanin on hepatictriglyceride

custompeptide STAT3 inhibitor

2015 Zhou X

J. Biol. Chem;290: 18361 -18369

SelectiveSensitization ofZinc Finger ProteinOxidation byReactive OxygenSpecies throughArsenic Binding

custompeptide

PARP-1 (native C3H1, C2H2, andC4 mutants, with cysteine residuesindicated in boldface) werecommercially synthesized PARP-1zfC2H2,GRASCKKCSESIPKDKVPHWYHFSHFWKV; PARP-1zfC3H1,GRASCKKCSESIPKDKVPHWYHFSCFWKV..

2015Bonaventura J

PNAS; 112:E3609 - E3618

Allostericinteractionsbetween agonistsand antagonistswithin theadenosine A2Areceptor-dopamineD2 receptorheterotetramer

custompeptide

A peptide derived from the HIVtransactivator of transcription, HIVTAT(YGRKKRRQRRRPQ), was fused toa peptide with the amino acidsequence ofhuman A2AR or D2R TM domains 5and 7 (TM5 and TM7; GenemedSynthesis124), to promote integration of theTM do

2015KshirsagarPR

BiotechnologyReports 6: 79–84

Highly efficient invitro regeneration,establishment ofcallus and cellsuspensioncultures and RAPDanalysis ofregenerants ofSwertia lawiiBurkill DNA

A total of 30 random decamerprimers (GenemedSynthesis Inc., TX, USA) werescreened for RAPD analysis, out ofwhich 12 primers were selected onthe basis of clarity of bandingpatterns. The protocol for RAPDanalysis was adapted from that ofWilliams et

2015 Alissafi TJ. Immunol; 194:5812 - 5824

De Novo–InducedSelf-Antigen–SpecificFoxp3+ RegulatoryT Cells Impair theAccumulation ofInflammatory Miscl MOG 35-55

2015 Joshi DCJ. Neurosci; 35:5293 - 5306

Deletion ofMitochondrialAnchoring ProtectsDysmyelinatingShiverer: Miscl MOG35-55

2015Walker-Caulfield ME

Journal ofNeuroimmunology; 278: 112–122

Dynamic changesin meningealinflammationcorrespond toclinicalexacerbations in amurine model ofrelapsing–remittingmultiple sclerosis Miscl

Six to eight week old mice wereimmunized subcutaneously at twoinjection sites on the posterior flankwith 100 μg PLP139–151 (GenemedBiotechnologies Inc.) emulsified with5 mg/mL CFA (IncompleteFreund's Adjuvant with desiccatedM. tuberculosis H37 (500

2015ShinwariJMA

The AmericanJournal ofHumanGenetics; 96:147-152

RecessiveMutations inCOL25A1 Are aCause ofCongenital Cranial Miscl

cDNA libraries human adult anddetal tissues

2015 Rodgers JMGLIA; 63:768–779

IL-17A ActivatesERK1/2 andEnhancesDifferentiation ofOligodendrocyte Miscl MOG35-55

2015 Sun AL in press

Homogeneouselectrochemicaldetection ofochratoxin A infoodstuff usingaptamer-graphene Miscl RT-OTA-D205F1

2015 Roberts RABiomaterials 72:1e10

Towardsprogrammingimmune tolerancethrough geometricmanipulation of Miscl

MOG35-55 peptide(MEVGWYRSPFSRVVHLYRNGK)

2015 Sripathi SR

Protein JDOI10.1007/s10930-015-9641-y

Prohibitin as theMolecular BindingSwitch in theRetinal Pigment Miscl

anti-prohibitinantibody

2015Gharagozloo M

Journal ofNeuroinflammation. 12:198

The nod-likereceptor, Nlrp12,plays an anti-inflammatory role inexperimental Miscl

f myelin oligodendrocyteglycoprotein (MOG35−55)

2015 Hussien YJ. Neurosci; 35:15921 - 15933

ER ChaperoneBiP/GRP78 IsRequired forMyelinating CellSurvival andProvides Protection Miscl MOG 35-55

2015 Awe OJ. Immunol; 195:3705 - 3715

PU.1 Expression inT Follicular HelperCells Limits CD40L-DependentGerminal Center B Miscl MOG35-55

2015 Barnes MJJ. Exp. Med;212: 1011 - 1020

Thelysophosphatidylserine receptorGPR174 constrainsregulatory T cell Miscl MOG 35-55

2016 Sripathi S

AlteredCytoskeleton as aMitochondrialDecay Signature in

2016 Lobo CLInfect. Immun;84: 1574 - 1584

Identification andCharacterization ofthe Rhoptry NeckProtein 2 inBabesia divergensand B. microti


bovis RON2 (BbRON2) serum wasgenerated in two rabbits by use ofits proprietary immunization regimenand…referred to here asBbRON2peptide

2016 Shao Q

J. Biol. Chem;291: 12432 -12443

A Germline Variantin the PANX1 GeneHas ReducedChannel Functionand Is Associatedwith MultisystemDysfunction


affinity-purified custom-made rabbitanti-human PANX1 polyclonalantibody (PANX1 CT-412, 0.5{mu}g/ml), generated against the C-terminal sequence of humanPANX1 ( 412NGEKNARQRLLDSSC 426 )

2016 Hastings T

Neurobiology ofDisease 91:247–261

Mic60/mitofilinoverexpressionalters mitochondrialdynamics andattenuatesvulnerability ofdopaminergic cellsto dopamine androtenone


The polyclonal “Genemed” rabbitanti-Mic60 antibody wasmade for our laboratory byGenemed Synthesis (San Antonio,TX)as previously described (Van Laar etal., 2008, 2009) and used forimmunodetection at a 1:500 dilution.

2016 Zervos E

Journal ofExperimental &Clinical CancerResearch. 35:39

Murine mesothelin:characterization,expression, andinhibition of tumorgrowth in a murinemodel of pancreaticcancer


Peptides representing murinemesothelin coding sequence,GVYGFQVSEADVRALGGLAC andCPPGKEPYKVDEDLIFYQN, were synthesizedand conjugated toKLH carrier proteins via the terminalcysteine residues(bold, Genemed Synthesis), andused for immunization oftwo

2016 Dutch REJ. Virol. 90: 9237- 9250

Inhibition of HumanMetapneumovirusBinding to HeparanSulfate BlocksInfection in HumanLung Cells and


Antipeptide antibodies to HMPV Fwere generated using amino acids524 to 538 of HMPV

2016 Lucchesi O


The signalingmodulecAMP/Epac/Rap1/PLCε/IP3 mobilizesacrosomal calciumduring spermexocytosis


The rabbit polyclonal antibodiesagainst Epac 1/2 were generatedusing the synthetic peptideLREDNCHFLRVDK, andaffinity purified on immobilized Epacpeptide

2016 Shlezinger N

MolecularMicrobiology:99(2), 393–406

Translocation fromnuclei to cytoplasmis necessary foranti A-PCD activityand turnover of theType II IAP BcBir1


The anti-BcBir1 antibodieswereprepared against two syntheticpeptides of conserved regionsof theBcBir1 BIR domains: C-KWPHKSLLPEELAKAG andC-EGDDPLKEHLKHSPN

2016 Ji ZMutagenesis; 31:297 - 308

Dose–Responsefor MultipleBiomarkers ofExposure andGenotoxic EffectFollowing RepeatedTreatment of Rats

custompeptide

.MeVHLTDAEK (MW 933), where L(bold font) is l-leucine-d 3 and A is l-alanline-d 4, were synthesised

2016 Carlsson E


SARM modulatesMyD88-mediatedTLR activationthrough BB-loopdependent TIR-TIRinteractions

custompeptide

For cellular experiments, a SARMBB-loop peptidetagged N-terminally with theAntennapedia homeodomainsequence(RQIKIWFQNRRMKWKK) for cellpenetration and C-terminally withK-rhodamine for detection

2016 Hlavaty KABiomaterials 76:1e10

Tolerance inductionusing nanoparticlesbearing HYpeptides in bonemarrowtransplantation

custompeptide

Peptides Dby(NAGFNSNRANSSRSS), Uty(WMHHNMDLI), and OVA323e339(ISQAVHAAHAEINEAGR)

2016 Malandro NImmunity 44,179–193

Clonal Abundanceof Tumor-SpecificCD4+ T CellsPotentiates Efficacyand Alters

custompeptide TRP-1 peptide

2016 Ehrhardt A

J. Biol.Chem.,291: 1854- 1865

Channel GatingRegulation by theCystic FibrosisTransmembraneConductanceRegulator (CFTR)First Cytosolic Loop

custompeptide

Experimental Procedures Reagentsand Constructs C-terminallybiotinylated peptides were obtainedfrom Genemed Synthesis as shownin Fig. 1. A biotinylated andscrambled control peptide for CL1-1B had the sequenceMFYKGIMRIKSTMLKQLAK..

2016 Hattori TPNAS, 113: 2092- 2097

Antigen clasping bytwo antigen-bindingsites of anexceptionallyspecific antibody for

custompeptide Histone peptides

2016 Mchulus KRBlood; 127: 1468- 1480

Synthesis anddephosphorylationof MARCKS in thelate stages ofmegakaryocytematuration driveproplateletformation

custompeptide

The myristoylated N-terminalsequence (MANS) and random N-terminal sequence (RNS) peptideswere synthesized by GenemedSynthesis Inc. The sequences areas follows: MANS: MA-GAQFSKTAAKGEAAAERPGEAAVAK(-fluorescean)-Amide RNS: MA-GTAPAAEGAGAEVKRASAEAKQAFK…

2016 Pavlos NJMol. Biol. Cell;27: 1367 - 1382

Sorting nexin 27couples PTHRtrafficking toretromer for signalregulation inosteoblasts duringbone growth

custompeptide

tetramethylrhodamine-labeledparathyroid hormone (PTH−TMR) bywhich TMR was added to the ε-amino group of Lys13 of PTH(1-34)was synthesized

2016 Walsh MR

Am J PhysiolCell Physiol; 310:C681 - C691

Analysis ofphosphorylation ofthe myosin-targeting subunit ofmyosin light chain

custompeptide

these peptides correspond toresidues 693-702 and 848-865 of ratMYPT1, respectively, and weresynthesized

2016 Steinman LPNAS; 113: 1600- 1605

Obeticholic acid, asynthetic bile acidagonist of thefarnesoid Xreceptor,attenuates

custompeptide MEVGWYRSPFSRVVHLYRNGK

2016ZamponiGW

Molecular Pain;12:1744806916642444

A cell-permeantpeptidecorresponding tothe cUBP domainof USP5 reversesinflammatory andneuropathic pain

custompeptide

d TAT-cUBP1-USP5, A biotinylatedCav3.2 III-IV linker peptide,USP5 human recombinant protein,and nonbiotinylatedUSP5 peptides that correspond todifferent domains, i.e.,nUBP, cUBP, UBA1, UBA2

2016 Saxena MJ. Immunol; 196:3754 - 3767

Bacterial DNAProtects MonocyticCells against HIV-Vpr–InducedMitochondrial

custompeptide

th three arginine to alaninemutations at sites R73, R77, andR80

2016 Phan-Lai Y

Clin. CancerRes; 22: 2207 -2216

The AntitumorEfficacy of IL2/IL21-CulturedPolyfunctional Neu-Specific T Cells Is

custompeptide

100 mug of neu peptide 98-114(RLRIVRGTQLFEDKYAL; neu p98)

2016 Gopal U

J. Biol. Chem;291: 10904 -10915

Activated α2-MacroglobulinRegulatesTranscriptionalActivation of c-MYCTarget Genes

custompeptide

mutant peptideLIGRTWNDPSVQQDIVFL (K 113–V), and scrambled peptideGTNKSQDLWIPQLRDVFI werepurchased f

2016 Adase CA

J. Biol. Chem;291: 11635 -11646

Non-coding Double-stranded RNA andAntimicrobialPeptide LL-37Induce GrowthFactor Expression

custompeptide LL-37 peptide

2016 Snyder CM

MolecularTherapy, 24, 8:1444-1455

IntratumoralInfection withMurineCytomegalovirusSynergizes with PD-L1 Blockade to

custompeptide

2016 Orchard I

CellularSignalling, 28, 9:1152-1162

Isolation andcharacterization ofthe corticotropin-releasing factor-related diuretichormone receptor

custompeptide

Pigment Dispersing Factor (PDF;NSELINSLLSLPKNMNDAamide)wassynthesized by GeneMed Synthesis

2016 Wang G in press

Design and surfaceimmobilization ofshort anti-biofilmpeptides

custompeptide

2016ZamponiGW

Cell Reports 17,2901–2912

TRPV1 NociceptorActivity InitiatesUSP5/T-typeChannel-MediatedPlasticity

custompeptide

Tat peptides (10 mg/mL; GenemedSynthesis)were bath applied and allowed topenetrate tissue for 3 min and thenremovedfrom bath to improve stability insubsequent recordings

2016 Behrends S

BiochemicalPharmacology122: 23–32

Heterodimerizationwith the β1 subunitdirects the α2subunit of nitricoxide-sensitiveguanylyl cyclase tocalcium-insensitive

custompeptide

the control peptide of the PDZbinding sequence of the ratsomatostatinreceptor subtype 3 (CKASTLSHL)

2016 Liu JK

Journal ofInorganicBiochemistry163: 45–52

Kinetics andthermodynamics ofzinc(II) andarsenic(III) bindingto XPA and PARP-1 zinc fingerpeptides

custompeptide

Synthetic peptides corresponding tothe first zinc finger motif ofPARP-1[GRASCKKCSESIPKDKVPHWYHFSCFWKV], a C4 mutant of thefirst zinc finger motif of PARP-1[GRASCKKCSESIPKDKVPHWYCFSCFWKV], and the zinc finger motif ofXPA [DYVICEECGKEFMDSYLMNHFDLPTC

2016KahramanGürsoy U

Anaerobe 39:31e38

Morphological andfunctionaladaptations ofFusobacteriumnucleatum exposed

custompeptide

Both HNP-1 and scrambled HNP-1were commercially purchased

2016 Weng X

Biochemistry andBiophysicsReports 6:149–157

Investigation of theantimicrobialactivity of soypeptides bydeveloping a high

custompeptide

Synthesized soy peptides PGTAVFKand IKAFKEATKVDKVVVLWTAwere purchased

2016 Kinoshita H

InternationalJournal ofCardiology 222:901–907

Intermittent localperiodontalinflammationcauses endothelialdysfunction of thesystemic artery viaincreased levels ofhydrogen peroxide

custompeptide gp91dstat

2016InestrosaNC

Codocedo andInestrosa BiolRes. 49:9

Wnt-5a-regulatedmiR-101b controlsCOX2 expressionin hippocampal

custompeptide

Control neurons incubated with ascramble peptide inNeurobasal medium

2016 Kang HS

Journal ofNeuroinflammation.13:133

Transgenicexpression of non-structural genes ofTheiler’s virussuppresses initialviral replication and

custompeptide

2016 Peng HBMC PlantBiology.16:197

Calcium/calmodulinalleviates substrateinhibition in astrawberry UDP-glucosyltransferaseinvolved in fruit

custompeptide

The peptide corresponding to theputative calmodulinbindingsite in FvUGT1 (aa 230–249)

2016 Sun T

J. Leukoc.Biol.100: 103 -110

HematopoieticLTβR deficiencyresults in skewed Tcell cytokineprofiles during a

custompeptide

VP6357-366 peptide(VGPVFPPGM; 2 mug/ml) or VP733-40 peptide (IVYRFLFV; 2 mug/ml))

2016 Zamvil SSPNAS. 113:14781 - 14786

Tolerancecheckpoint bypasspermits emergenceof pathogenic Tcells to

custompeptide AQP4 peptides

2016 Lu LJ. Cell Sci.129:3922 - 3934

A ternary complexcomprisingtransportin1, Rab8and the ciliarytargeting signal

customproteinantibodies His-tagged Arl13b-C-ter antibodies

2016 Yu H

J. Biol. Chem.291: 19079 -19091

OpposingFunctions of the N-terminalAcetyltransferasesNaa50 and NatA in


The rabbit polyclonal antibodyagainst human Naa50 was raisedusing His 6 -tagged recombinantNaa50 as the antigen

2016 Mimura LANNeuroscience317: 130–140

Association ofmyelin peptide withvitamin D preventsautoimmuneencephalomyelitis Miscl

MOG35-55 peptide(MEVGWYRSPFSRVVHLYRNGK)

2016FuenzalidaM

Neurobiology ofDisease 86:109–120

Wnt signalingpathway improvescentral inhibitorysynaptictransmission in a Miscl Wnt-5a analog, Foxy-5

2016 Zamvil S

NeurolNeuroimmunolNeuroinflammatio

CNS accumulationof regulatory B cellsis VLA-4-dependent Miscl MOG 35-55 peptide

2016 Miller SJ. Immunol; 196:1455 - 1459

Cutting Edge:MicroRNA-223Regulates MyeloidDendriticCell–Driven Th17Responses in Miscl MOG 35-55 peptide

2016 Fink PJ. Immunol; 196:2450 - 2455

Cutting Edge:Enhanced ClonalBurst Size Correctsan OtherwiseDefective MemoryResponse by CD8+ Miscl OVA 257-263 peptide

2016 Motl RW

Journal ofNeuroscienceResearch94:907–914

Effects of exercisein a relapsing-remitting model ofexperimental Miscl PLP139–151(10 mg; SP-52298-5)

2016 Sartori A

CNSNeuroscience &Therapeutics 22:807–816

TolerogenicVaccination withMOG/VitDOvercomesAggravating Effectof C. albicans in Miscl

MOG35–55peptide(MEVGWYRSPFSRVVHLYRNGK)

2016 Yasuda Y

Pflugers Arch -Eur J Physio.468:1555–1564

High oxygenmodifiesvasodilator effect ofcysteine viaenhanced oxidativestress and Miscl gp91ds-tat and sgp91ds-tat

2016 Godoy JA

Mol Neurobiol10.1007/s12035-016-0203-x

Quercetin ExertsDifferentialNeuroprotectiveEffects AgainstH2O2 and AβAggregates in Miscl

The synthetic Aβ1–42 peptide,corresponding to wild-type humanAβ, was obtained

2017Gómez-Lagunas F

ComparativeBiochemistry andPhysiology, PartA 203: 297–303

Desensitization andrecovery of crayfishphotoreceptors.Dependency oncircadian time, and

custompeptide

PDH (NSELINSILGLPKVMNEA-NH2) sequence

2017SchwartzMZ

journal ofsurgicalresearch. (207):

Is OM-3 synergisticwith GLP-2 inintestinal failure?

custompeptide GLP-2

2017 Tang D

Biosensors andBioelectronics89: 659–665

Homogeneouselectrochemicaldetection ofochratoxin A infoodstuff usingaptamer–grapheneoxide nanosheets Miscl RT-OTA-D205F1

· Year Author Journal Title Product Category Products 1991 Science, Dec 1991; 254: 1669....

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Transcript of · Year Author Journal Title Product Category Products 1991 Science, Dec 1991; 254: 1669....