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Usefulness and Validation of an Easy HIV Risk Practice and Clinical Conditions

Questionnaire

C. Gómez Ayerbe1, A. Muriel2, C. Santos3, P. Pérez Elías3, A. Díaz De Santiago1, C. Quereda1, R. Barea3, L. Polo3, E. Navas1, J.M. Hermida1, S. Moreno1, M.J. Pérez Elías1,4, DRIVE Study group.

1 Hospital Ramón y Cajal (HRyC), Infectious Diseases Department (Dep). 2 HRyC, CIBERESP, Statistics Dep. 3 Centro de Salud García Noblejas, Madrid, Spain. 4 IRYCIS, Madrid, Spain.

THPDC0101

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Background• In Spain, the number of PLWHIV infection increases every year1. • Around 45-50% of the patients have a delayed diagnosis (<350 CD4/mcl)

and 30% advanced disease (<200 CD4/mcl)1 .• Moreover, up to 30% of the HIV patients are unaware of their own status1.

• European Guidelines recommend HIV testing in persons with Risk Practices and/or Clinical Conditions (RP&CC) associated with HIV infection2.

• RP&CC assessment should be done before indicating HIV testing, but in the clinical practice this is not routinely investigated.

• An structured RP&CC Questionnaire could increase a higher implementation of RP&CC assessment, and HIV testing.

1. CNE, ISCIII Annual Report 2013; 2. HIV in Europe, march 2012 www.hiveurope.eu;

Conflict of Interest DisclosureNo Conflict of interest

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Materials and Methods• Patients 18-60 years visiting Emergency

Room or Primary Care Center were performed:

1) HIV- Risk Practice and Clinical Conditions Questionnaire

2) HIV-Rapid Test

Results (1)Objetive

• To assess the Reliability, Feasibility and Predictability of an structured RP&CC Questionnaire.

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Results (2)

Conclusions

1. A reliable and Feasible self RP&CC Questionnaire discriminated all non HIV infected patients without missing any diagnosis.

2. Screening HIV RP&CC plus HIV testing in patients with RP&CC, offered a more efficient HIV screening strategy.

3. Best Predictability was obtained when combining Risk Practice and Clinical Conditions items.

Sustancial

RELIABILITY

FEASIBILITY

Self administered

90.8%

Filled in paper 98.1%

Median time to complete

3 min(2-4)

Needed clarification

17.9%

Global Quest Risk Practice

Clinical Conditions

Sensitivity 100% (84.6-100)

86.4% (65.1-97.1)

91% (70.8-98.9)

Specificity 49% (47.7-50.4)

61.3% (60-62.6)

74.4% (73.2-75.6)

Positive Predictive Value

0.80% (0.50-1.22)

0.92% (0.55-1.43)

1.45% (0.88-2.23)

Negative Predictive Value

100% (99.9-100)

99.9% (99.7-100)

99.9% (99.8-100)

PREDICTABILITY