Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012
description
Transcript of Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012
![Page 1: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/1.jpg)
Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012
Lars Lundmark Analytical Chemistry, Department of Chemistry, Umeå University, S-901 87 Umeå, Sweden
![Page 2: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/2.jpg)
Background
ISP ,Uppsala University Sweden Support Network between Bangladesh ,Lao and Cambodia Universities in research cooperation and exchanging of knowledge
MonitoringArsenic contamination of groundwater has been known forLong time in in Bangladesh and now some part of Cambodiaand Lao PDR face same problem and thus testing of As andHg is very important task to avoid health effect for people using this water
![Page 3: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/3.jpg)
Lars Lundmark Umea University has been involved longtime in Mekong region (MRCS)setting up Water Quality laboratories in Thailand ,Vietnam, Lao PDR and Cambodia. In Umea University we now focus on speciation . “Determination of exact chemical form or compound in which an element occurs in a sample. For example determination of whether arsenic occurs in form of trivalent or pentavalent ions or as part of an organic molecule.
![Page 4: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/4.jpg)
Monitoring
We need powerful analytical techniques that can provide highly selective, sensitive, rapid, and precise measurements
HPLC
SFC
Separation
GC
Detection
MS
ICP-MS
AAS
MIP-AES
![Page 5: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/5.jpg)
GC-ICP-MS at Umea University Sweden
![Page 6: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/6.jpg)
Determination of Mercury in Fish (11.5 kg)
![Page 7: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/7.jpg)
Organic Mercury compound and in particular methyl mercury are nowdays treated as a potent neurotoxin (lethal oral dose is 0.2g) The serve toxic actions of methylmercury was recognized during the Mianamata incident in Japan .There it was observed that woman with symptoms of mild methylmercury poisoning gave birth to children with severe neurological damages that was overall analogoues to cerebral palacyusCadmium is another very toxic compound which stays in kidney and accumulates for every year od lifetime .This metal can be analyzed by ICP,ICP-MS or GFAAS (Graphite furnece Atomic Absorbance spectroskopy
![Page 8: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/8.jpg)
Sampling for Cadmium in Moose kidney
http://www.bipm.org/utils/common/pdf/final_reports/QM/P43/CCQM-P43.pdf
![Page 9: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/9.jpg)
Or in white hare (Type of wild rabbit)
![Page 10: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/10.jpg)
AAS lab in Saigon National University Vietnam
![Page 11: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/11.jpg)
Mercury analyser using old Perkin Elmer AAS and Amalgalmation trap
![Page 12: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/12.jpg)
Hydride AAS system in Lao PDR
![Page 13: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/13.jpg)
The Hydride system setup in RUPP ,CAmbodia
![Page 14: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/14.jpg)
Determination of PhTs in BCR (CRM-477) by MI-SSID
TPhT• No difference between the results obtained before and after correction for degradation.• Dephenylation of TPhT does not give rise to errors if the incipient and spiked species are degradated to the same degree.
DPhT• Uncorrected DPhT values agree well with values reported by others.• Values corrected for dephenylation of TPhT are 50% lower than the indicative value. The reported indicative value for DPhT is likely to be too high.
MPhTNo significant difference between uncorrected and corrected values for MPhT because of the low concentration of DPhT compared to MPhT and low dephenylation of TPhT and DPhT (<10%)
Conclusion …..
![Page 15: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/15.jpg)
Future aspects
Study of the metabolism of butyltin compunds in bilological systems.
Oral administration of MI-spike of organotins in laboratory animals (Sanz-Medel et.al. Anal.Chem. 2005,77,7724)
Widen/enhance the application of the MI-spike in other fields
Geochemical modelling, calculation of transformation adsorbtion, desorbtion and transformation rates in soils/sediments
![Page 16: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/16.jpg)
Slut
Tack!
![Page 17: Workshop in PhnomPenh regarding As and Hg determination 12-14 Dec 2012](https://reader035.fdocuments.in/reader035/viewer/2022070421/568160e8550346895dd01dbc/html5/thumbnails/17.jpg)
a) Ratio 120/124 for TPhT
MPhTs
ssmTBT
MPhTspmTPhTMPhTspMPhTsp
DPhTs
ssmTPhT
DPhTspmTBTDPhTspDPhTsp
ssmTPhT
TPhTspmTPhTTPhTspTPhTsp
TPhTs
NFAtAtRAtRAt
NF
NFAtAtRAtRAt
NFAtAtRAtRAt
NN
10120124124/120,
124,
124/120,
120,
10
7120124124/120,
124,
124/120,
120,
7120124124/120,
124,
124/120,
120,
b) Ratio 120/122 for TPhT
MPhTs
ssmTBT
MPhTspmTPhTMPhTspMPhTsp
DPhTs
ssmTPhT
DPhTspmTBTDPhTspDPhTsp
ssmTPhT
TPhTspmTPhTTPhTspTPhTsp
TPhTs
NFAtAtRAtRAt
NF
NFAtAtRAtRAt
NFAtAtRAtRAt
NN
10120122122/120,
122,
122/120,
120,
10
7120122122/120,
122,
122/120,
120,
7120122122/120,
122,
122/120,
120,
c) Ratio 120/118 for TPhT
MPhTs
ssmTBT
MPhTspmTPhTMPhTspMPhTsp
DPhTs
ssmTPhT
DPhTspmTBTDPhTspDPhTsp
ssmTPhT
TPhTspmTPhTTPhTspTPhTsp
TPhTs
NFAtAtRAtRAt
NF
NFAtAtRAtRAt
NFAtAtRAtRAt
NN
10120118118/120,
118,
118/120,
120,
10
7120118118/120,
118,
118/120,
120,
7120118118/120,
118,
118/120,
120,