WONKWANG UNIVERSITY, IKSAN. - SONSIKsonsik.org.np/wp-content/uploads/2018/12/SONSIK-7th... · 2018....

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WONKWANG

UNIVERSITY,

IKSAN.

Since 1990 Nepalese students had started studying in South Korea. However, after

2000 only the students flow at South Korea was increased rapidly. Even after rapid

increase of students flow at South Korea there did very few students know each

other and less opportunity to share knowledge/ experience gained after coming

in Korea. On 2004 group of intellectuals from different university gathered at Sun

Moon University, Cheonan Korea, after deep thought and discussion Society of

Nepalese Students in Korea (SONSIK) was established and had its first official

meeting at Sun Moon University. Initially the goal of SONSIK was to have frequent

meeting with different Nepalese scholars in Korea with the changing time the

mission which began 12 years ago is still the goal today to share/strengthen the

bond and knowledge between more than 2000 fellow members of Korean

Universities. Furthermore, the goal is set a step ahead to make SONSIK the only

intellectual organization where the policy maker can look up to. Over the past

years we have grown beyond Korean peninsula and our effort have not gone

unnoticed. For the proper functioning of the organization SONSIK has an annual

basis formal structural executive body to manage indented plans.

Please click http://sonsik.org.np/ for detail about our organization.

Decisive and actionable policies together with promotion and facilitation of

knowledge and technology transfer are indispensable for national development.

Exploring Nepal’s research possibilities and an effective diaspora policy to

transfer knowledge and technology from abroad are the essence of any diaspora-

led development planning. Though contributions of the Nepalese diaspora across

the globe are of great importance to the country’s development, the skill gained

by the diaspora is yet to be utilized for utilization of Nepalese resources.

The Society of Nepalese Students in Korea (SONSIK), being the sole

community of the Nepalese students and academicians in Korea, is working

continuously for the promotion of Nepalese diasporic role along with the ways

they can contribute to the development of Nepal through assistance in policy

making, and Knowledge and technology transfer. In Korea, the Nepalese

diaspora community, which is close to 40,000 in numbers, comprises of mainly

three different professional groups that can mutually share and contribute their

expertise in the development process. The fore and foremost unit belongs to the

scholars (mostly holding PhD degree) and entrepreneurs, who are competent in

science, technology, social sciences, and entrepreneurships. The second group

consists of students, who strive in selecting a study area that are deemed

necessary for Nepal’s development. The third and the largest group is made of

migrant workers, who hold a considerable leverage in Nepalese economy, mainly

through remittances and the skills acquired in Korea. Hence, combining these

three groups in a single platform will not only help bring innovative ideas but

will also inspire each other to initiate actions that are much needed in Nepal. The

outcome of this seminar is expected to assist policy makers in formulating

necessary platforms so that that it can bring all these important aspects together

in Nepal’s development process. SONSIK will thus act as a bridge by facilitating

the interaction between the development experts and the policy responsible

representatives. In this context, this conference will focus on "Exploring Role of

Nepalese Diaspora in Korea for the Research and Development in Nepal” mainly

concentrating on the research opportunities in Nepal and involvement of skilled

Nepalese resources for research based development. This seminar will thus focus

not only on the theoretical discussion on transfer of technology and skilled

personnel but also on the research based policies that Nepal may formulate and

implement to ensure an effective contribution in strengthening our economy.

SOCIETY OF NEPALESE STUDENTS IN KOREA 7th Educational Seminar : Introduction

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Brief Introduction:

http://sonsik.org.np/

-To make a plateform where a group of Nepali experts can engage in provocative

discussions and fruitful exchanges of ideas for the development of provincial

education policy of Nepal.

-To make a concrete conclusion report regarding the educational policy from 7

group as per their respective provinces of Nepal.

-To make a proper document and submit to the Government of Nepal.

-Share the knowledge and technology transfer regarding to research in science,

engineering and technology

-The close interaction to integrate and empower the scientific community

covering various facets of researches to the till date.

-Share more gain more through Poster Presentation Session.

- To shorten the bridge of difficulties that may incur while living in Korea.

BJECTIVES: VENUE DETAIL

Venue: Iksan is the beautiful city situated on north Jeolla Province. This city is also called “The city of Jewelry”. We can find a lot of beautiful historical temples, jewelry museum and some famous universities in the city of iksan. Wonkwang University, which is only one Won Buddhism University, is one of the main University of this city and our seminar is going to be held on same university. The decoration and beauty of Wonkwang University attracts all the students and visitors coming to iksan. Wonkwang University had got best decoration award from Korean government last time. We hope all the Nepalese students attending the seminar will enjoy the beauty of Iksan city as well as Wonkwang University.

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Program Schedule Second Day : Dec, 30 (Sunday), 2018 (Formal Program -(9:30- 4:30 PM)

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Time Schedule

3:00 – 3:15 PM Registration

3:15 - 3:30 PM Sit taking and Group Formation

3:30 - 3:45 PM Introducing moderator and brief concept of interaction.

3: 45- 4: 30 PM Group discussion

4:30 -5:05 PM Presentation by each group

5:05 -5:15 PM Comments or question on Presentations

5:15 – 5:30 PM Summarization and closing.

5:30-6:00 PM Farewell for 14th EC.

6:00 –6:45 PM Dinner Time

6:45 -9:45 PM Cultural Night-song, dance,literature,and many more

Program Schedule

First Day : Dec, 29 (Saturday), 2018

Key Programs

-Workshop

-Keynote Speaker (2)

-Speaker :

-Session I – (3)- (Role of Diaspora for Nepal)

-Session II- (3)- (Science and Technology)

-Session III-(4)- (General)

-Poster Presentation

-Award ceremony

-Farewell for 14th EC

-Cultural Program

Interaction Program on: ‘Provincial Education policy in Nepal: current

situation, future direction, suggestion to government and our role.’

Moderators : Dr. Devi B. Basnet, Dr. Agni Raj Koirala,

Dr. Lokendra Chand, and Dr. Ekraj Baral

Time Event

8:30 – 9:30 AM Registration and Breakfast

9:30 – 9: 45 AM Chairs

9:45 – 9:50 AM Inauguration (Lighting of candle), Batch distribution

9:50 – 9:53 AM Nepali National Anthem

9:53 – 9:55 AM Remembrance for martyrrs (Maun Dharan)

10:55 – 10:05 AM Welcome speech by program coordinator (Mr. Prakash Devkota)

10:05 – 10:10 AM Wonkwang University promotional video

10:10 – 10:20 AM Welcome performance (Nepali cultural fashion Show)

10:20 – 10:25 AM SONSIK activity promotional video

10:25 – 10:30 AM Speech by Guest, Mr. Kim Do Young, Director, Samdong International

10:30-10:35 AM Visit Nepal 2020 Promotional Video

10:35 – 10:40 AM Speech by Special guest , Prof. Dr. Chung Soo Jin (정수진 교수님) Director,

Center for international affair, Wonkwang University

10:40-10:45 AM Speech by NRNAPresident (Laxmi Gurung)

10:45 – 10:55 AM Speech by Chief guest

H.E. Mr. Arjun Jung Bahadur Singh, Ambassador, Embassy of Nepal, Seoul.

10:50 – 10:55 AM Book launching (Guidebook for foreigners in Korea)

11:05 – 11:10 AM Closing remarks by Mr. Tulsi Poudel, President, SONSIK

11:10 – 11:35 AM Keynote speaker 1 (Prof. Dr. Hong- Seob So, Professor, School of Medicine, WKU and

CEO of NADIAN Bio.

11:35 – 12:00 AM Keynote speaker 2 ( Mr. Kian Shakya, Deputy Chief of the Mission)

11:50 – 12:30 PM Group Photo and LUNCH break

Educational Seminar- Session-I- Role of Diaspora for Nepal

12:35-12:55 PM Presentation 1. (Dr. Devi B. Basnet)

12:55-1:15 PM Presentation 2 (Dr. Agni Raj Koirala)

1:15 – 1:30 PM Presentation 3 (Dr. Ramesh P. Pandey)

1:30 – 1:35 PM Session-II – Science and Technology

1:35 – 1:50 PM Presentation 4 (Dr. Ramakanta Lamichhanne)

1:50 – 2:05 PM Presentation 5 (Dr. Sanjaya Poudel)

2:05 – 2:20 PM Presentation 6 (Mr. Shree Krishna Acharya)

2:20 – 2:50 PM

Coffee Break and Poster Presentation Time

2:50-3:00 PM (Session-III)- General

3:00 – 3:15 PM Presentation 7 (Dr. Bhojindra P. Tulachan)

3:15 – 3:30 PM Presentation 8 (Mr. Ramesh Pariyar)

3:30 – 3:45 PM Presentation 9 (Dr. Pradeep Adhikari)

3:45 – 4:00 PM Presentation 10 (Dr. Raghbendra Kumar Dutta)

4:00 – 4:30 PM Award Ceremony and Group photo

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S P E A K E R

-2005, Masters in Public Administration -2003, Bachelor in Education

- 2002, Masters in Business Studies -2000, Bachelor in Business Studies

Professional Background:

-Counselor/Deputy Chief of Mission at the Embassy of Nepal in Korea since July 2015

(Served as CDA for 13 months in between). -Under Secretary at North East Asia Division of the Ministry of Foreign Affairs in 2014-15

-Acting Consul General at the Consulate General of Nepal in Hong Kong in 2013

-Consul at the Consulate General of Nepal in Hong Kong from February 2010 to Jan

-Section Officer, South Asia and SAARC Division at the Ministry of Foreign Affairs

-Section Officer at the Ministry of Physical Planning and Construction from 2007 to 2009.

-Copyright Officer in Nepal Copyright Registrar’s Office in 2006/2007.

Publications: 5+ in reputed journal.

Mr Shakya involved in various national and international organization

Mr. Kiran Shakya

Role of Diasporas in the Research and Development : Mr. Kiran Shakya Deputy Chief of Mission

Abstract: With the waves of globalization and liberalization, the cross –boundary movements of people

have increased tremendously and Nepali people are too not the exceptional. With the growth in

size and quality of Nepali Diasporas around the world including the Republic of Korea, their

willingness to contribute in the research and development and be engaged in nation building

have started to take shapes. There is a need of two-ways approach from the Nepali Diasporas as

well as the Government of Nepal in nurturing the sense of belongings and create an environment

for engaging Diasporas as the development partners. All related stakeholders should collaborate

and work to convert the waves of brain drain into brain gain.

S P E A K E R

Title: NAD+ Application in Total Care Therapy for Cancer Patients: From

Bench to Clinic

Hong-Seob So 1Director & 2CEO 1Center for Metabolic Function Regulation & Department of Microbiology, Wonkwang

University School of Medicine, 2NADIAN BIO Ltd. 344-2 Shinyong-dong Iksan, Jeonbuk

570-749, Korea.

Abstract In this presentation, I will talk about the research projects of Nepalese students studying the

master's or doctoral course in my laboratory. I would like to briefly introduce the research

field of NADIAN BIO Co., Ltd., which was founded on the basis of accomplishment of

Korean and Nepalese young researchers. I will also try to discuss ways to promote mutual

research cooperation between Nepal and Korea.

Hong-Seob So, Professor, PhD Wonkwang University School of Medicine,

Department of Microbiology, Iksandaero 460, Iksan, Jeonbuk, Korea Telephone: +10-9697-7374 (010-9697-7374), Email: [email protected]

Dr So is a renowned professor of Wonkwang University School of Medicine and Director of

Center For Metabolic Function regulation (CMFR) designated by the Korea Research

Foundation & the Ministry Of Science and Technologies, Korea. He received BS and MS

in Microbiology from Seoul National University, and PhD in Medical Science from

Jeonbuk National University, School of Medicine, in Korea. He did post-doctoral research

from 2001 to 2003 at the Dept of Lab. Med. of UPENN, USA. He is also cofounder and

CEO of NADIABIO Ltd., founded in 2016 to develop drugs for neutropenia and cancer-

related fatigue. His researches address the elucidation of pathophysiologic mechanisms of

chemotherapy-induced adverse effect and its prevention. In addition, he is interested in

elucidating the regulatory mechanisms of metabolic organelles, NAD+/NADH, and

transcriptional factors in various disease developments. He also tries to establish the

fundamental technologies for controlling metabolic/non-metabolic inflammatory diseases

and metabolic bone diseases through the regulation of metabolic organelles, NAD+/NADH,

and transcriptional factors.

mailto:[email protected]

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SESSION CHAIR-BIOGRAPHY

Biography PEAKERS bstract

Session -I ‘Role of Diaspora for Nepal’

S A &

Bhanu Shrestha (PhD)

Associate professor

Kwangwoon University, Seoul, since 2008.

E-mail: [email protected] mob: 01045904460

Dr Shrestha is one of the founding members as well as vice-chairman of the ICT-

Advanced Engineering Society based in Seoul, Korea. He is also a president of

Nepal Korea Friendship Society based in Kathmandu, Nepal. He has presented

many papers and published many papers on SCI/E indexed journals. He serves as

an editor-in-chief of International Journal of Advanced Engineering (IJAE) and

editorial board members of some international journals as well such as Editorial

Board Member of Science Publishing Group, USA, International Journal of

Advances in Microwave Technology, etc. He is also a director of the institute of

internet broadcasting and communication (IIBC). He is also awarded as the

achievement award from IIBC, Best paper award, etc. He is honored two time as

‘Honorable Citizenship’ from Seongbuk gu, and Seoul Metropolitan City. He

achieved ‘Honorary 3rd Dan’ in Taekwondo confer from Kukkiwon, Korea.His

research interests are in RFIC/MMIC/IPD device and system.

Name: Madhav Prasad Neupane

Research Professor Chonbuk National University, South Korea

Telephone: 010-3049-4039, Email: [email protected]

Dr. Neupane is a materials scientist currently working as a research professor at

Chonbuk National University (CBNU), South Korea. He received his Bachelor

and Master degrees from Tribhuvan University, Nepal in 1994 and 1996,

respectively and Ph.D. degree from CBNU in 2009. He served as university

postdoctoral fellow (2009-2011) at CBNU, research professor (2011-2016) at

CBNU and senior scientist (2017-2018) at Nepal Academy of Science and

Technology (NAST), Nepal.

His primary research interests focus on the regeneration of bone for large critical

size defects, surface modification and characterization of implant biomaterials for

dental and orthopedic applications, modification of tissue engineered ceramic

scaffolds, protein-biomaterials interactions and cell-biomaterials interactions in

vitro and in vivo. In addition, his research focused on using nanomaterials for

drug delivery in target site to reduce toxic side effects of drugs to normal cells.







Dr. Devi Bahadur Basnet -2005-2001, Ph.D. from Sun Moon University.

-1997-1995, M.Sc., Tribhuwan University, Kirtipur


-Present-2008, Senior Research Scientist, Medytox, Inc. Ochang, South Korea.

-2008-2006, Post Doc, Ewha Woman’s University, Korea.

-2000-1994, Lecture, different college and school in Nepal.

Publication: 15+ (International scientific articles)

Research Interest: Development of antibody therapeutic through new isolation, screening

and engineering of antibodies. Generation of high producing stable mammalian cell line.

Dr Basnet enrollments in various national and international organizations, and social activities.

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Building a Prosperous Nepal: Role of Nepalese Abroad Dr. Devi B. Basnet

Senior Research Scientist at Medytox,Inc, Exe-NRNA-ICC member, Coordinator for Asia-

Pacific region for 1st NRNA Knowledge convention 2018.

Formation of majority government, at present, has shown a great relief of volatile internal

political structure as political stability is considered as a prerequisite for development.

However, it is yet to be proved in practice.

Nepalese expatriates reside in different countries mainly for two purposes: employment and

study leaving their dependents at home country. NRNA has been actively working into various

fields in Nepal since its establishment entangling Nepalese nearly from 78 countries. The role

of educated, skilled and experienced Nepalese emigrants for Nepal's development has often

recited by government and civil societies. To substantiate this, NRNA has already initiated and

accomplished many noteworthy works in Nepal to cope with a slogan "Happy Nepali,

prosperous Nepal."

In this talk, I will share my experiences and views that are accumulated since the very

beginning of my involvement at various capacities with NRNA both in national and

international since NRNA-Korea establishment. Particularly, I will focus on the issues such as

science and technology, public motivation, economic development. Additionally, I will try to

speak about how can we contribute and be a part of it for nation building mission as non-

resident Nepali.

NRNA's recently held “Global Knowledge Convention 2018” in Kathmandu in October this

year is a vivid and notable attempt of our engagement for this process. I will present and

discuss on this mentioning how can we make a professional connection globally focusing

Nepal's development. For example, over 40,000 Nepalese are working in Korea with different

capacities and fields. In this session, I will also talk how this educated and skilled human

resources can be helpful for Nepal's prosperity mission. Finally, I will shed light upon

knowledge-based economy as well.

Key words: Stability, Sustainable development, NRNA, Knowledge-based economy

Dr. Agni Raj Koirala -2015, Ph.D., Korea Center for Artificial Photosynthesis,

Center for Nanomaterials, Department of Chemistry, Sogang University,

-2001, Master of Sciences in Chemistry (physical) Tribhuvan University.

-1999,Bachelor of Sciences (Chemistry) Tribhuvan University, Nepal.

Professional Background

- Postdoctoral researcher, Department of Chemistry, Sogang University

-lecturer and Research associate, in different college and school in Nepal.

Research filed: Photochemical and Photoelectrochemical reduction of CO2 to liquid fuel,

Photo and electrochemical water splitting, Fuel cell for clean and alternative fuel

Publications : 13+ (International journals), 2 patents and a book chapters.

Dr Koirala enrollments in different organizations and attained different national and

international conferences.

Consequences of Global warming and fuel crisis in Nepal: Utilization of

Solar light as an alternative and renewable source of energy. Dr. Agni Raj Koirala, Korea Center For Artificial Photosynthesis (KCAP),

Sogang University

Global warming and future fuel crisis are the two most prominent problem that our planet is

facing at this time. These problem becoming more and more severe day by day and will be

most critical problem for entire human being in the coming decades. The CO2 concentration in

the atmosphere rises from 280 pomp (1790) to 403 ppm (2016) and further soon reaches to 570

ppm by the end of the 21st century if it increases with the present rate. The increase in the

carbon dioxide concentration in the atmosphere contributes to the increase in global

temperatures and climate changes due to the ‘‘greenhouse effect’’. The estimated rise in

temperature is from 4.7 to 8.6oF by 2100. The major contributor for the CO2 level increase is

the excessive use of carbon rich fossil fuels (coal, oil, and natural gas etc.). Any steps in

decrease the CO2 emission has significant role in saving our planet from these problem. One

way is to use the CO2 as a raw material to prepare the various chemicals methanol, formic acid,

ethanol, olefins ets which can be used as fuel instead of fossil fuels. As we know the plants are

capable of converting the CO2 and water into glucose in the presence of light through the

natural photosynthesis. However, this process is only 0.5-2% efficient and the energy content

of the resulting biomass is too low. Mimic the natural photosynthesis with high efficiency is

one of the most important steps in solving the global warming and future fuel crisis known as

the “Artificial photosynthesis”. Around 11.7 militones of energy is required by Nepal in 2014, out of this almost 80% from the

biomass, 12% oil products, coal 4%, electricity 1% and 3% hydropower. The energy supply of

Nepal still mostly depends upon the biomass and oil products, due to the excessive use of

biomass and oil products the CO2 concentration increasing every year which causes the rise in

global temperature that ultimately causes the melting of the glaciers in the Himalaya. The

melting of the glacier is one of the biggest problem in Nepal because glaciers are the source of

drinking water, irrigation and hydroelectric power in Nepal. Global warming and future fuel

crisis are the two most prominent problem that our planet facing at this time. these problem

becoming more severe in the coming time.

SPEAKER SPEAKER

Volu

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Dr. Ramesh Prasad Pandey

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-2014-Ph.D., department of life science and biochemical engineering,

Sun moon University, Korea.


-2016-Assistant Professor, department of life science and biochemical engineering,

Sun moon University, Korea.

-2014-Research Professor, Sun moon University, Korea.

- Visiting Professor, Swiss Federal Institute of Technology Zurich, Switzerland.

Publications : 60+ (International journals), 9 patents and 5 book chapters.

SPEAKER

Commercial Farming of Medicinal Herbs in Nepal and Recent Biotechnology

Aspects Ramesh Prasad Pandey Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University, South

Korea

Plants have been used for multiple purposes including health care for more than

5000 years. Of the total plants present in the Earth, 10% are considered

medicinally important. In Nepal, many plants are being used as medicinal herbs.

However, the harvesting of these herbs from natural resources is unsustainable.

Moreover, the information about these plants are not scientifically documented. In

this context, Nepal is facing huge challenge to expand its possibility of

bioprospecting, national, and international trading. In another hand, recent

biotechnological tools made possible to synthesize the biologically important

constituents in tiny microbial cells, also called as microbial cell factories. Such

advanced genetic engineering techniques including synthetic biology enabled to

produce plant originated anticancer drugs such as taxol (naturally isolated from

Taxus) and antimalarial drug Artemisinin (naturally isolated from Artemisia) from

microbial cells. The production of these important drug from microbial system is

replacing traditional plant extract approaches. Biotechnological scenario of plant

metabolites production from microorganisms is also challenging medicinal herbs

farming worldwide. In this aspects, this talk will be mainly focused on how

Nepalese Scientific Society/Nepal Government can address the challenges of

traditional medicinal herbs preservation, farming, international trading, and

promotion.


Session -II ‘Science and Technology’

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Dr. Taraman Kadayat (PhD)

Research Scientist

New Drug Development Center,

DGMIF, South Korea

E-mail: [email protected] mob:010-5503-5148

Dr. Taraman Kadayat: is a Nepal Pharmacy Council registered Pharmacist. He

received his B. Pharm degree with honor from Pokhara University. He did his

Master and PhD in Pharmacy from one of the top University of South Korea. He

has served as Pharmacology Instructor and Pharmacy In-charge of Nepalgunj,

Medical College and teaching Hospital. He has extensive experiences in new drug

discovery and development researches specially for cancer and diabetes therapy.

Currently he is working as a Research Scientist and Principal Investigator at

Daegu Gyeongbuk Medical Innovation Foundation (DGMIF). He has 30+

scientific papers in reputed International Journals and he also serve as reviewer in

reputed journal. Dr. Kadayat has received several national and international

awards, grant, scholarship. He has participated in many national and International

Conference, Forum, Meeting, and Seminar. Dr. Kadayat is also socially very

active in various national and international organization.

Dr. Krishna P. Dhakal Research professor Sungkyunkwan University Department of Energy Science, Telephone: 01044261985 Email: [email protected]

Dr. Krishna P. Dhakal is a physicist who works in the field of optical imaging and

spectroscopy of the nano-material. He completed his Ph. D. from the Department

of energy science and institute of basic science (IBS), Sungkyunkwan University

Suwon, in the field of optical properties characterization. Currently he is working

as a Research professor in the SKKU, Suwon after two years postdoctoral

experience in the Yonsei university. His major interest is the exploration of the

fundamental physical phenomena. He works on optical/electronic properties of

atomically thin two dimensional materials including nonlinear optical properties

for the exploration of the fundamental science. Dr. Dhakal have published several

scientific papers in reputed internationals journals.

Dr. Ramakanta Lamichhane

-2017, Ph.D., the Department of Oriental Pharmacy, Wonkwang University.

-2014, Master in Oriental Pharmacy, Wonkwang University


-Postdoctoral researcher, Department of Oriental Pharmacy, Wonkwang University

-Lecturer, Bhageshwor academy of health sciences, Dhangadi.

Research interest : Biological activity of plants (specially obesity and diabetes), Care and

treatment of Diabetes

Publication : 12+ (National and International journals)

Awards :– Korean Government Scholarship Award for Master’s Degree

Lekhnath Scholarship for Bachelor’s Degree – Pokhara University

SPEAKER

Making Better and Comfortable Life for the Diabetic Patients in Nepal Ramakanta Lamichhane

Wonkwang University, College of Pharmacy, Deptartment of Oriental Pharmacy,

Iksan,Jeonbuk, Republic of Korea

Email: [email protected] Diabetes mellitus is a chronic, progressive metabolic disorder. There are two categories, type 1 diabetes mellitus

(T1DM) and type 2 diabetes mellitus (T2DM), of which T2DM comprises almost 90% cases. Diabetes is emerging

as a major global problem worldwide with a global prevalence 8.8% (2017 AD). Nepal is also a country with large

number of diabetic population. A recent systematic review and meta-analysis showed a prevalence rate of T2DM of

8.4% in Nepal.

Diabetes management requires long-term follow-up with continuous access to medication and specialist care. The

high medical cost (2.5 times higher compared to non-diabetics) of diabetes is truly a big economic burden for the

poor country like Nepal. The different complication of diabetes like retinopathy, nerve damage, cardiovascular

disease, amputation, etc. contributes for its high medical cost. On top of that the management and treatment of the

disease has become further challenging due to limited health care professionals (0.67 per 1,000 population) and

facilities which are mostly concentrated in urban areas, low disease awareness among the population; various socio-

cultural factors; educational strategies; and very few programs to detect, manage, and prevent diabetes and its

complications.

Health care professionals and policymakers have to come together to assess the increasing burden of diabetes and

design appropriate preventive and management strategies. For the primary prevention, the awareness programs

regarding diet, exercise and early medication should be done in all levels. To the diabetic patients the government

should focus on ease access of good medical and health care services. Diabetes management requires long-term

follow-up with continuous access to medication and specialist care. The basic facilities of glucose monitoring and

counseling on diabetes should be available right from the ground level of health care divisions like primary health

care centre (PHCC). The big national hospitals should start special care centre for the diabetes patients. The

treatment guideline should be prepared for the diabetes so that all the health care professionals can follow same

guideline for the treatment and management of diabetes. In Korea, the government has planned to start to bear 90%

of the total cost of health care of diabetic patients from next year (2019). The insurance companies here bear some

part of expense of medication for diabetic patients. There is a good facility of checkup and counseling of diabetes

right form the public health post. The big hospitals are equipped with separate diabetic centers for complete

treatment of diabetes. The Korean diabetes association (KDA) has been involving in various activates like

preparation and update of treatment guideline for diabetes, research works and journal publication regarding

diabetes etc.

Overall, some proper regulations and changes are urgent in Nepal regarding diabetes, for the quality of life of

diabetic patients. This will ultimately help to reduce the social and economic burden of both the diabetic patient and

the country itself.

Keywords: Diabetes, quality of life, Nepal, treatment, management.




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Dr. Sanjaya Paudel -2011, Ph.D. , Astrophysics, University of Heidelberg, Germany

- 2007, M.Sc. in Physics, M.Sc. in Physics, Cosmology

Central Department of Physics, Tribhuvan University, Nepal.


- Research Scientist, Department of Astronomy, Yonsei University.

-KASI Postdoctoral fellow, Korea Astronomy and Space science Institute (KASI), Korea

-VIRAGE fellow, Alternative Energies and Atomic Energy Commission (CEA), Paris, France

-Postdoctor, Astronomisches Rechen-Institut, Heidelberg, Germany

Publications : 30 + (International journals)

News/Press release: 3 (In the areas of , Astrophysics)

Dr Paudel enrollments in various activities and attained different national and international

conferences and talks.

Astronomy Research in Nepal: an opportunity Become Data Scientist Dr. Sanjaya Paudel

Post-doctoral fellow at Department of Astronomy, Yonsei University

Astronomy research has been considered the origin of scientific practice. Starting from

trying to understand the basic natural phenomenon such as motion of planets and the sun, it

is now quite diverse and sophisticated. There are three different beaches -computational,

observational and theory. Unlike other science research field, experimental data of

Astronomy research are well archived and they are mostly free to public. Anyone can use it

and explore their research idea. In this talk I would like review observational astronomy

research in Nepal which is done with publicly available archived data and how this provides

an opportunity for the students to learn the data driven science.

SPEAKER

Mr. Shree Krishna Acharya -Ph.D. candidate. Mokpo National University,

Department of Engineering.

-M.S. degree from Mokpo National University, Korea, in 2017.


-ICT engineer at Doti distict

-Lecture at Thahapathali campus

His research interests are in intelligent system applications to power systems.

A novel hybrid short-term load forecasting model based on optimum k-

means baseline and deep learning methodology 1*Shree Krishna Acharya, [email protected], 1 Muan, Mokpo, South Korea

One of the most crucial tasks for utility companies is load forecasting in order to plan future

demand for generation capacity and infrastructure. Decomposition process is often

considered as powerful technique in residential load forecasting. Although, inherent discrete

items of load series such as general trend, seasonality and unexpected variations, plays vital

role for short-term load forecasting (STLF) in residential sector, only statistical and other

hybrid technique utilizes its leverages. Recently, deep learning and its state-of-art is evolved

with significant accuracy. However, issues related with aggregate forecasting is remarkably

solved but individual houeholds forecasting are still challenging. In this paper, a novel

methodology is proposed, including an optimum selective k-means baseline and deep

multilinear pereceptron (MLP) forecasting methodology. Proposed method considered that

selective k-means baseline is the combination of inherent general trend and seasonlity and

discover the remaining resiudals from entire load profiles. The training process of MLP

utilized only uncertain resiudals and identified their prediction. The simulation result shows

the efficacy and validation of the proposed methodology.

SPEAKER



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Session -III

‘General ’

S A &

Dr Madhu Sudhan Atteraya (PhD)

Assistant professor

The Department of Social Welfare

Keimyung University, Daegu South Korea

Dr. Atteraya’s research areas include family welfare, equity in health care, social

justice, migration and integration, and international maternal, newborn and child

health. Dr Atteraya serves as a Focal Point for the Partnership for Research on

Maternal, New Born, & Child Health (PMNCH; the Partnership), which is hosted

by the World Health Organization (WHO). He has attended many domastic and

international workshops and conferences. He has also published many scientific

journal. Dr. Atteraya is an Associate Editor of the BMC Women's Health

(Springer) journal.

Balkrishna Ghimire (PhD)

Post-Doctoral researcher

Korea National Arboretum/Plant Conservation Division

Gyeonggi-do, Pocheon

Telephone: 010-2353-4902

Email: [email protected]

Dr. Ghimire is a plant taxonomist. His PhD dissertation at Kangwon National

University titled "Taxonomy of Taxaceae s. l. based on Anatomical Characters

and Cladistic Analysis.“ His major areas of interests: anatomy and morphology

of higher plants in relation to taxonomy. Dr. Ghimire has published many

scientific papers in reputed journals. Currently he is working as a plant seed

morphologist in the seed bank and seed testing laboratory in Korea National

Arboretum Gyeonggi-do, Pocheon.


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Sushil Bhandari (PhD)

Post-Doctoral researcher

Wonkwang University,.

E-mail: [email protected] mob: 01058059994

Dr Bhandari is a registrated Pharmacist of Nepal. He completed his B. Pharm

degree from Pokhara University. He studied Master and PhD in Wonkwang

University, his dissertation titled “The study of metabolic functions of a

peroxisomal protein in vivo during early development using a zebrafish mutant”.

He is wellknown in the field of Zebrafish related experimentations. He have

published more than nine papers in reputed scientific international journal and

written a book chapter as well. He have more than three years work experience in

Pharmaceutical company. He has presented many papers in national and

international seminars. He is also awarded as the Best paper award, KIST Best

Research Award. Dr Bhandari area of interest are Molecular and cellular Genetics,

Metabolic Disease, Pharmacology.

Dr Bojindra Tulachan -Ph.D. from the Department of OB/HR , Ajou University.


-Serviced as the Head of the English Department ,NIST

-Worded as Editor-In-Chief for Gazette, the GSIS publication of Ajou University.

-Teaching experiences to undergraduate level and graduate students.

Dr Tulachan research interests are industrial and labor relations, trade unions and

unionization, collective bargaining, comparative studies, mindfulness and mindful

interventions, and positive psychology and positive psychology interventions

Poetics of Research Bojindra Prasad Tulachan, PhD Organizational Behavior/Human Resource Management, Ajou University, Korea

[email protected]

Most of the young researchers are in dilemma in the acknowledgment of the poetics of

research. They are fundamentally unaware of what, when, how and why of the research in the

area of their research interest. Therefore, the central objective of the poetics of research in

any domain is to advance the current research, theoretically and practically. In doing that, the

emerging researchers are to be aware of the fact that they need to consider the theoretical

advancement, finding newer or archeological investigation, methodological contribution, the

larger and broader coverage of the participants, rigorous analysis through analytical tools,

both qualitative and quantitative ones. Further, comparative analysis, meta-analysis, counter

thesis, alternative thesis, conceptual thesis and debate or discursive thesis are the symmetry of

research. Thus, one has to be aware of as many ways as possible to enrichen one’s capital of

research. In that, the strategic play in the pool of research capital is likely to produce the

rigorous research that could be highly cited, contributive to the scholarship itself and the

society at large. Further, the poetics of research are discussed substantially in the conclusion

section.

SPEAKER







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Mr. Ramesh Pariyar -Ph.D. candidate, Neuropharmacology, Wonkwang University, Nepal.

-2016-2014, M.Sc. M.Pharm, Wonkwang University.

-20012-2008, B.Pharm, Pokhara University, Nepal.


-Researcher, Department of Pharmacy, Wonkwang University, Korea.

- Quality assurance officer at Universal Formulation Pvt. Ltd.

Awards : -2016- young scientist award , wonkwang university

-2017- young scientist award , wonkwang university

Publication : 8+ (National and International Journals)

Mr Pariyar research interests are epigenetic, PSYCH-K, conscious and subconscious mind.

SPEAKER

How to Reprogram Subconscious Mind 1Ramesh Pariyar [email protected] 1 Wonkwang University, South Korea.

Human beings are the most superior organism on the earth due to their powerful brain. The

wiring and firing between the neurons are responsible for the creation of thought, awareness

and consciousness. The mind has two elements; the conscious and the subconscious, and

they are interdependent. The subconscious is the equivalent of the habit mind where as the

conscious mind is a creative mind. Interestingly when we are awake, majority of activities

in human beings is controlled by subconscious mind, representing 95% and only 5% is

controlled by the conscious mind. The Subconscious mind is purely stimulus-response,

which process large data and, is unobserved. It controls most of our decisions, actions,

emotions and behaviors. The instincts and perceptions are the program of our subconscious

mind. The programming of the subconscious is most influentially originated between the

ages of birth and six years old. During this period of time nature, nurture and our

surrounding (i.e. family, relatives, and community members) modeled our subconscious

mind. During this period, the predominant brain wave frequencies were dalta (0.5 Hz) and

theta (4-8 Hz). These frequencies are associated with reverie, trance, hypnosis, super

learning and imagining. Subconscious mind began programming at young stage and major

resulted learned behaviors includes, disempowering, self-sabotaging and limitation. Subconscious program are unfixable and unchangeable behaviors, which is challenging to

change in later life. Despite of its nature, large variety of research is going on to address

these facts through reprogramming techniques. which include hypnosis, repetition, energy

psychology, and high impact events. By learning how to harness our minds to promote

growth is the secret of life.

Keynotes: subconscious, conscious, mind

Dr. Pradeeep Adhikari -2014-2017, Ph.D. from the Department of Biology Education,

Jeju National University.

-2010-2013, Master in Science (M.Sc.) Zoology,

Central Department of Zoology


- Postdoctoral researcher, National Institute of Ecology, Korea

-Researcher, Animal Taxonomy and Morphology Laboratory, Jeju National University

-Lecturer/ Teacher in different college and school in Nepal.

Publication : Total: 17 (National and international journals)

Reports : Total: 6 (In the areas of wildlife and climate change)

Dr Adhikari enrollments in various national and international organization

SPEAKER

Biodiversity Conservation and Research for Sustainable Development of Nepal

Pradeep Adhikari, Ph.D.

National Institute of Ecology, Korea

[email protected] Nepal is a highly distinct and diverse country harboring an extraordinary variety of landscape,

wildlife, habitats, and cultures. It has tremendous geographic diversity that extends from lowland

Terai (60m) to the permanently snow-covered mountains ‘Himalaya’ (8,848m) with various eco-

climates resulting in exceptionally rich biodiversity in the country. Although Nepal covers only

0.1% of the world’s land mass, it is home to 3.2% and 1.1% of the world’s known flora and fauna,

respectively. The country has 118 ecosystems, 35 forest types, and four biodiversity hotspot

harboring 212 species of mammals, and 878 species of birds. Nepal is extremely rich in floral

diversity (11,968 species) having 1,792 medicinal plants, 370 endemic plants, 28 gymnosperm,

and 6,653 angiosperms.

Many florae (~200 species) and faunae (birds 167 spp., mammals 55 spp., herpetos 64 spp.) of

Nepal are being threatened. Loss and degradation of natural habitats, poaching, invasive species,

disease, and human-wildlife conflict are predominant threats of biodiversity in the country. The

Government of Nepal and various conservation agencies are currently active in biodiversity

conservation and research programs. However, their paying efforts are not sufficient. The research

activities are mainly focused on the ecological survey, monitoring, and populations study. Due to

the lack of efficient manpower and sufficient resources very few studies are found on wildlife

disease, molecular ecology, and conservation genetics. Therefore, the contribution of Nepalese

researchers who are studying/working in different foreign countries specialized with the

biodiversity-related subjects will certainly help to cope with this situation. The biodiversity of

Nepal can provide enormous economic and community benefits using biological resources in

forestry, fishing, farming, and recreation. These activities can increase the prosperous economy in

the nation and sustainable development of rural communities. Currently, more than 30 lakh

people are directly or indirectly depend on various biological resources for their livelihood. The

ecotourism has been providing about 100,000 jobs and supporting to about 1.5% to GDP in 2017.

Therefore, tourism industry based on the excursion of biodiversity of Nepal required to promote.

Moreover, training and education to local people for proper use of biodiversity, environment

protection, and pollution control are required for long-term conservation of biodiversity.



Dr. Raghbendra Kumar Dutta -2018-2014, Ph.D. from the Department of Medicine,

Wonkwang University, Nepal.

-2014-2012, M.Sc. In Medicine, Wonkwang University, Nepal.

-2005-2002, B.Sc in Microbiology, Tribhuvan University , Nepal.


-Postdoctoral researcher, GIST, Korea.

- Quality control officer , Pharmaceutical industry of Nepal.

Publication : Total: 5 +(International Journals)

Dr Dutta research interests are Peroxisome, Adipocytes, ROS, cilia

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SPEAKER

Crosstalk between peroxisome and adipocytes

1*Raghbendra Kumar Dutta, 1Joon No Lee, 1Yunash Maharjan, 1Zhi-qiang Liu, 1Se-Jin Kim, 3Ye-Shih Ho, 2Seong-Kyu Choe, and 1Raekil Park 1E-mail: [email protected], Department of Biomedical Science and Engineering,

Institute of Tntegrated Technology, Gwangju Institute of Science and Technology, Korea 2 Department of Microbiology and Center for Metabolic Function Regulation, Wonkwang

University School of Medicine, Republic of Korea 3Institute of Environmental Health Sciences and Department of Biochemistry and Molecular

Biology, Wayne State University, United States

Peroxisomes are dynamic organelles that participate in a diverse array of cellular processes,

including β-oxidation of branched-chain and very-long-chain fatty acids, which results in

reactive oxygen species (ROS) production. ROS production characterizes the imbalance

between oxidant and antioxidant agents. To counterpoise the damaging effect of ROS, the

antioxidant peroxisomal enzyme catalase reduces H2O2 to water and oxygen. Although

peroxisome is ubiquitously expressed, the roles of this organelle are mostly studied in liver. The

present study investigated the role of catalase in lipid metabolism in adipocytes during nutrient

deprivation using catalase knockout (KO) mice. We found that catalase depletion during

starvation induces ROS that triggered hyper activation of lipolysis in white adipocytes. Also,

we found that hepatic and serum levels of triglycerides were dramatically decreased in catalase

KO mice during starvation, which is potentially associated with the elevated fat consumption

through the activation of lipolysis mediated by ROS in adipocytes. Furthermore, isoproterenol,

a beta-adrenergic receptor treated to mimic fasting as in vivo induces lipolysis that is

accompanied by increase in ROS produced by peroxisomal oxidase in KO primary adipocytes.

KO fasted and isoproterenol treated adipocytes also stimulates uncoupling protein 1 (UCP1)

through ROS accumulation in both vivo and in vitro respectively. However, an antioxidant N-

Acetyl Cysteine (NAC), co-treatment with isoproterenol attenuated the ROS generation by

peroxisomal oxidase ACOX1 that suppressed the undesirable lipolysis and UCP1 induction in

KO adipocytes. These findings suggest that catalase plays an important role in the liver

function and lipid metabolism during nutrient deprivation

Abstract For Scientific Poster Presentation


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Poster Presentation

Title

Anti-amyloidogenic effect of ethanol extract from the aerial parts of

Mallotus japonicus on β-amyloid induced memory impairment in

Alzheimer’s disease mouse model

Phytochemical screening and Assessment of Biological activities of

Eighteen Medicinal plants from Nepal

Study of antioxidant and antibacterial activity of Neem (Azadirachta i

ndica), Tulsi (Ocimum sanctum) and Fresh Cow urine

(Bos indicus).

Prevalence of Smear Positive Pulmonary Tuberculosis in Kailali,

far-Western Region of Nepal

Anticancer effect of 4-methoxydalbergione in neuroblastoma

SH-SY5Y cell

Development of self-microemulsifying tablets from newly synthesized

c-Met inhibitor by quality by design approach

Experimental and Numerical Exploration of Terahertz Wave

Generation in a Gaseous Medium

Challenges and Opportunities for International Students in Korea:

Case Studies

A Hybrid solar PV-Power Forecasting based on K-means and GRU

Network:

Super-Speed Tube Train System, Effect of external loads on its

performance and its Contribution for the development of Nation:

SONSIK Activities, Challenges and Opportunity

Possibilities of zebrafish as tools for drug discovery from medicinal

plants of Nepal.

Potential impact of climate change on the species richness of subalpine

plant species in the mountain national parks of South Korea

Presenter Name

Abinash Chandra Shrestha

Prakash Raj Pandeya

Nisha Adhikari

Subham Sharma

Tonking Bastola

Julu Tripathi

Rajaram Shrestha

Nabin Bohara

Shree Krishna Acharya

Prakash Devkota

Dirgha Raj Joshi

Suhsil Bhandari

Pradeep Adhikari

Poster No

SP-1

SP-2

SP-3

SP-4

SP-5

SP-6

SP-7

SP-8

SP-9

SP-10

SP-11

SP-12

SP-13

SP-14

SP-15

SP-16

SP-17

SP-18

SP-19

Rajmani Sigdel

Prakash Devkota

Nirmal Acharya

Tulsi Paudel

Bhusan Shrestha

Ananta MS Pradhan

Causes of road accident and safety situation in Nepal

3R- Reduce, Reuse and Recycle

Scholarship in Korea

SONSIK educational Seminar Overview: First to Present.

A brief introduction to Yarsagumba (Cordyceps sinensis) and orange

caterpillar fungus (Cordyceps militaris) and their cultivatio

Effect of spatial soil depth model in shallow landslide prediction

Poster Abstract

Scientific Poster (SP-1)

Anti-amyloidogenic effect of ethanolic extract from the aerial

parts of Mallotus japonicus on Alzheimer’s disease mouse model

Abinash Chandra Shrestha1*, Ju Eun Kim1, Ha Neul Ham1, Hyo Shin Kim1,

Jae Yoon Leem1* College of Pharmacy, Woosuk University, Wanju, Jeonbuk 55338, South

Korea Presenter (Email : [email protected], +8210-9657-3346) Co-author (Email : [email protected], +8210-8879-2447) Abstract Alzheimer’s disease, is a chronic neurodegenerative disease having neuronal loss and is

caused by a amyloid beta (Aβ) accumulation in brain. Limitations and side effects of

established drugs necessitate the development of safer and more effective agents for

treatment of central nervous system disorders. Mallotus japonicus has been reported to

possess therapeutic features likes antioxidant and anti-melanogenic. Taking into these

facts, we developed curiosity to investigate the biological target and its mechanisms on

various activity of Mallatus japonicus like anti-amyloidogenic. Various biological tests,

electron microscopy, total antioxidant status, Morris water maze and Passive avoidance

were performed. The extracts showed significant inhibition of acetylcholinesterase,

prevention of Aβ oligomerization and potent antioxidant activity. Moreover, MJE with

concentration 250 mg/kg displayed improvement of learning and memory suppression in

beta-amyloid induced Alzheimer's disease model. Collectively, our findings provides

valuable information for the researcher who are developing therapeutic agents against

neurodegenerative diseases. Key words: Alzheimer’s disease, Mallotus japonicus, Acetylcholinesterase, Anti-oxidant,

Anti-amyloidogenic.



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Phytochemical screening and Assessment of Biological activities of

Eighteen Medicinal plants from Nepal 1*Prakash Raj Pandeya, 1Ramakanta Lamichhane, 1Kyung-Hee Lee, and 1Hyun-Ju

Jung [email protected], Department of Oriental Pharmacy and Wonkwang-

Oriental Medicines Research Institute, Wonkwang University, Sinyong-Dong,

Iksan, 570-749, South Korea

Abstract The present investigation is aimed in the assessment of anti-oxidant and anti-inflammatory

activities, and screening the phytochemicals present in the methanol extracts of 18 species of

locally used ethnomedicinal plants collected from Dadeldhura district Nepal. Macerated methanol extracts were screened for the presences of pharmacologically active

phytochemicals such as alkaloids, saponins, tannins, flavonoids etc. A quantitative assessment

of total phenol and flavonoid contents was performed. Anti-oxidant activities of the obtained

extracts were screened using DPPH and ABTS•+ radical scavenging method. The phytochemical analysis of these medicinal plants exhibited the presence of medicinally

important phytochemicals. The Ageratina adenophora (leaves), Ficus auriculata Lour (bark),

Silngo (bark and leaves), Cynoglossum zeylanicum (whole plant), Centratherum

anthelminticum (seeds), Tinospora cordifolia (stem), Rubus ellipticus (whole plant), and

Bergenia ciliate (whole plant) contains high amount of total phenols and flavonoid contents.

Assessing anti-oxidant activity, Ficus auriculata Lour (bark), Dendrophthoe falcate (leaves),

Silngo (bark), Girardinia diversifolia (rhizome), Ageratina adenophora (leaves), and Rubus

ellipticus (whole plant) has better potential. The present study provides evidence that some of the screened plants contain medicinally

important bioactive phytochemicals and this justifies the use of plant species as traditional

medicine and offers the possibilities to be potential therapeutic medicines for treatment of

various diseases. Keywords: Medicinal plants, phytochemical screening, anti-oxidant activity, RAW 264.7

macrophage, total phenol, flavonoid content


Study of antioxidant and antibacterial activity of Neem (Azadirachta

indica), Tulsi (Osmium sanctum) and Fresh Cow Urine (Bos indicus). Adhikari N, Neupane S, Oli S, Rana A and Bhandari R Crimson College of Technology Butwal-13, Rupandehi, Nepal


Abstract: The aim of the research was to evaluate antioxidant and antibacterial activities of three extracts

individually as well as synergistically and to scientifically proof that the traditional practice of

Neem, Tulsi and fresh cow urine for this existing activity. The leaves of A. indica and O. sanctum were shade dried, then the extract was prepared by

grounding 50 g of leaves using mortar and pestle and the yield was successively soaked by four

different solvents; methanol, chloroform, hexane and cow urine for about 72 hours with

frequent shaking and stirring. The fresh cow urine used in this experiment was collected from

nearby, Kamdhenu Gaushala. Four bacterial pathogens; Escherichia coli, Staphylococcus

aureus, Proteus vulgaris and Klebsiella pneumoniae were enrolled for the test and the disc

diffusion method was used to screen the antibacterial activity. Along with fresh cow urine, the

four different extracts of each plant were prepared at varying concentrations and was soaked on

Whatmann filter paper discs with standardized discs of antibiotics, Ciprofloxacin and

Gentamicin which were applied on inoculated plates of Muller Hinton agar. For synergistic

activity, previous each extract of both plants were combined in the same ratio and the

antibacterial activity was carried out in the same way as mentioned above. Likewise, for

antioxidant activity extract of A. indica and O. sanctum and fresh cow urine was carried out

using the DPPH radical scavenging method. Ascorbic acid was used as the standard and the

scavenging activity was measured by spectrophotometric method. The absorbance was recorded

at 519 nm and the percentage reduction was calculated as per the percent reduction formula. The antibacterial activity was evaluated on the basis of maximum zone of inhibition.

Chloroform and hexane extract of A. indica showed maximum inhibition against S. aureus and

K. pneumoniae while methanolic extract of O. sanctum showed maximum inhibition against S.

aureus. As a synergistic effect, the cow urine extract of A. indica and O. sanctum showed the

highest inhibition against E. coli and P. vulgaris. Likewise, the antioxidant activity was

calculated as per the percent reduction and which was highest in methanolic extract of both A.

indica and O. sanctum. Hence, we can conclude that almost the entire different extracts of Neem, Tulsi and Cow urine

has shown the antioxidant and antibacterial effects. The individual extracts showed the highest

antibacterial and antioxidant effects. Among them, the extract of both plants in fresh cow urine

i.e. synergistic activity showed a greater zone of inhibition.

Keywords: antioxidant, antibacterial, DPPH, antibiotics







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Prevalence of Smear Positive Pulmonary Tuberculosis in Kailali,

far-Western Region of Nepal Suresh Jaiswal1, Subham Sharma2, Raju Pandey3, Mithilesh Kumar Jha4, Bishnu Prasad Neupane5, Ishor Sharma6, Komal Prasad Malla7, Hari Prasad Kaphle8 1*Department of Laboratory Science, School of Health and Allied Sciences, Pokhara University,

Kaski, Nepal, 2Department of Pathology, Malakheti Hospital, Kailali, Seti Zone, Nepal, 3Department

of Laboratory Science, School of Health and Allied Sciences, Pokhara University, Kaski, Nepal, 4Department of Pharmacology, Brain Science & Engineering Institute, Kyungpook National

University School of Medicine, Joong-Gu, Daegu, Republic of Korea, 5Department of

Pharmaceutical Sciences, School of Health and Allied Sciences, Pokhara University, Kaski, Nepal, 6Department of Public Health, School of Health and Allied Sciences, Pokhara University, Kaski,

Nepal, 7Department of Pharmaceutical Sciences, School of Health and Allied Sciences, Pokhara

University, Kaski, Nepal, 8Department of Public Health, School of Health and Allied Sciences,

Pokhara University, Kaski, Nepal


ABSTRACT Tuberculosis (TB) is a leading public health problem worldwide particularly in the

developing countries like Nepal. The objective of this study was to know the status of TB

infection cases among the patients visiting to Malakheti Hospital, Kailali, Seti zone, Nepal. A

cross-sectional study was carried out on total of 545 patients made up of inpatients and

outpatients at the Malakheti Hospital, Kailali, Seti zone between January 2008 and July

2009. A questionnaire was designed to obtain age, sex, ethnic group, occupation, marital

status, address, and religion. Three consecutive days samples were collected. The World

Health Organization (WHO) procedure for diagnosis of TB at the district level was adopted

for this study by the Ziehl- Neelsen (Zn) method using hot technique and examined with oil

immersion using binocular light microscope. Of the total 545 cases under investigation only

428 completed the study. The total number of male and female were 340(62.4%) and

205(37.6%) respectively. Of the total visiting patient 485 were from Kailali, 53 were from

Kanchanpur and 7 were from others place. While age wise distribution less than 11 years, 11-

19,19-60 and 60+ were 11(2.0%), 33(6.1%), 403(73.9%) and 98(18%) respectively. Total

positive case of the pulmonary tuberculosis by staining method was found to be 47(10.98%)

and negative cases were 381(89.02%). No significant relation was found with the variables.

The study concludes that still it has high TB infection in Nepal and the prevention and

treatment should be more improved.

Keywords: Tuberculosis, Acid Fast Bacilli (AFB), microscopy, WHO


Anticancer effect of 4-methoxydalbergione in neuroblastoma

SH-SY5Y cell 1*Tonking Bastola, 1Ramesh Pariyar and 1Jungwon Seo *Lead presenter 1 E-mail: [email protected], Institute of Pharmaceutical Research and Development,

College of Pharmacy, Wonkwang University, Iksan 570-749, Republic of Korea

Neuroblastomas are the most frequent extra-cranial malignancy in children. Here we have

investigated the effect of Methoxydalbergione (4-MD), isolated from Dalbergiaodorifera, in

human neuroblastoma SH-SY5Y cells. MTT assay and LDH assay showed that 4-MD

decreased the cell viability and induced cytotoxicity in neuroblastoma SH-SY5Y cells.

Caspase-3 activation and cleaved PARP were noted and meanwhile, pre-treatment with the

caspase inhibitor reversed the cytotoxic effect of 4-MD which indicate the induction of

caspase-3 dependent apoptotic cell death. Furthermore, 4-MD induced the formation of LC3-

II that indicates the autophagic process which was confirmed by the accumulation of acidic

vesicular organelles. Upon blocking the autophagy process using 3MA and bafilomycin, 4-

MD induced cell death was significantly reduced, which indicate the autophagy regulated cell

death. We also observed the accumulation of reactive oxygen species (ROS). Finally,

pretreatment with the antioxidant N-acetylcysteine completely abolished the 4-MD-mediated

apoptosis and autophagy indicating the critical role of ROS in 4-MD-induced anticancer

effect. In conclusion, 4-MD induced cell death in human neuroblastoma SH-SY5Y cells from

autophagy which was independent of apoptotic cell death and these events were primarily

triggered by the generation of ROS, suggesting its therapeutic application in the treatment of

neuroblastoma.

Keywords: Neuroblastoma, 4-Methoxydalbergione, Apoptosis, Autophagy, ROS



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Development of self-microemulsifying tablets from newly

synthesized c-Met inhibitor by quality by design approach 1Tripathi Julu, 1Thapa Prakash, & *,1Jeong Seong Hoon College of Pharmacy, Dongguk University, Korea

E-mail address: [email protected],

This present investigation is aimed to develop self-microemulsifying tablets (SME-tablets) to

improve the in vitro dissolution of poor water soluble drug, novel c-met inhibitor, ABN401.

Quality by design (QbD) approach was applied to prepare and optimize self-microemulsifying

drug delivery system (SMEDDS) of ABN401. The influence of various material attributes such

as Capryol 90 (X1), the Cremophor EL (X2) and Transcutol HP (X3) on the response variables

(Y) was evaluated using this approach. The result of particle size revealed that an increase in

concentration of Cremophor EL and Transcutol HP decreased the particle size of nanoparticles

(p < 0.05). Similarly, the % of drug release at 15 min showed Cremophor EL and Transcutol HP

had positive effects on drug dissolution while Capryol 90 had negative effects on it.

Subsequently, the optimized SMEDDS formulation showing minimum droplet size (52.71 ±

0.056 nm), maximum drug release in 15 min (92 ± 1.1 %), and maximum zeta potential value

(-7.30 ± 0.16 mV) was selected. It was then adsorbed into Neusilin US2 to prepare SME tablets

by direct compression method. The in vitro study showed more than 90% of the drug was

released from the SME-tablets within 60 min. No significant difference was observed between

the optimized SMEDDS and SME-tablets. In addition, physico-chemical characterization of

solid SMEDDS was performed using Scanning Electron Microscope (SEM), Differential

Scanning Calorimetry (DSC), and Fourier Transmission Infrared Spectroscopy (FTIR). The

results showed the absence of interaction between the excipients and drug as well as indicate

that the drug is in the solubilized form in the solid SMEDDS which might be the reason for

improved dissolution of the used drug. Therefore, this study showed the importance of QbD

approach in designing and optimizing SMEDDS and the potential use of SME-tablets for the

oral delivery of poorly water-soluble drugs, ABN401.

Key words: c-Met inhibitor, quality by design, self-microemulsifying tablet, self-

microemulsifying drug delivery system


Experimental and Numerical Exploration of Terahertz Wave

Generation in a Gaseous Medium

Rajaram Shrestha1,2 and Kyung Taec Kim1,2 1 Center for Relativistic Laser Science, Institute for Basic Science, Gwangju 61005, Korea 2Dept. of Physics and photon Science, Gwangju Institute of Science and Technology, Gwangju 61005,

Korea

E-mail: [email protected]

Terahertz (THz) wave generation has great importance as it can be used for THz pump-probe

experiments, nonlinear THz optics and spectroscopy. We report on the investigation of THz

wave generation in a gaseous medium both numerically and experimentally. Using the

Ammosov-Delone-Krainov (ADK) tunneling ionization model, describe the ionization of N2

by the laser pulse and estimate the generation of a THz radiation, we perform theoretical

calculations in which a few-cycle laser pulses (at the wavelength of 800 nm) with the peak

intensity of 1014 W/cm2 interacts with N2 gas for different carrier envelope phases (CEPs).

However, THz signal generated by the few-cycle laser pulses is very weak. Here we show

that the THz radiation depicts a strong dependence on the CEP of the laser and most

pronounced at the specific CEP (90 degree). Furthermore, the amplitude of the THz radiation

decreases with increasing the duration of the laser pulse. In addition, we are also setting up

an experiment to demonstrate THz wave generation in a gaseous medium at a 1kHz

repetition rate with two-color femtosecond laser pulses at the wavelength of 800 nm. In this

setup, we are mixing fundamental and second harmonic field to ionize the gas, emitting THz

radiation.



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Challenges and Opportunities for International Students in Korea:

Case Studies 1,*Nabin Bohara, 2Taraman Kadayat, PhD 1,*E-mail: [email protected], Yeungnam University, South Korea 2 New[a1] Drug Development Center, Korea Medical Innovation Foundation. South Korea

It is well-accepted fact that education is very important for all. There is no border for getting

an education. Nowadays, many students would like to get an education from different parts of

the world because students can learn a new culture, lifestyle, education system, new

knowledge and get more confidence being out of their comfort zone. However, getting an

education in other countries may not be an easy task. There are many challenges that have to

be faced by international students. Since early 2000, the Korean Government has invested a lot of money and effort to attract

international students in South Korea. Nowadays, South Korea is considered one of the top

destinations for several international students especially from South East Asia including

China, Vietnam, Uzbekistan, Mongolia, Cambodia, and Nepal. However, there are still lots of

challenges for international students in South Korea. In this presentation, I will discuss major challenges and opportunities for international

students (especially Nepalese students case studies) in Korea. In addition, I will highlight the

Korean Government’s policy and successful case studies with the example of Nepalese

students.


A Hybrid solar PV-Power Forecasting based on K-means and GRU

Network 1*Shree Krishna Acharya, [email protected], 2 Muan, Mokpo, South Korea

Abstract:

Recently, renewable energy sources (RES) such as solar, wind etc., are evolving rapidly due

to advancing of smart grid technology. Although the pattern of solar power generation is

complex and non-linear, it’s research is fascinating towards the deep learning technique due

to reliable and robust non-linear cognition. This paper deals with solar PV power forecasting

by employing combination of k-means clustering and Gated Recurrent Unit (GRU) network.

The k-means clustering provide the classification of similar PV –profiles into three sub-

groups such as Sunny, Cloudy, and Rainy days. Moreover, GRU network is state-of-art of

deep learning network and demostrate better acknowledge over repetitive data contained by

sequence data. As a consequence, proposed hybrid methodology potray significant

forecasting accuracy in the simulation results.


SONSIK Activities, Challenges and Opportunity Dirgha Raj Joshi, Secretary of SONSIK 15th EC, PhD Scholar, College of Pharmacy, Korea

University Sejong Campus, Sejong, Korea

Society of Nepalese Students in Korea (SONSIK) is an umbrella organization of

Nepalese students and intellectual in Korea. After its establishment in 2004, its

activities are going continuously. To this constructive approach-based activity

many students contributed their valuable time and their intellect. Its my great

honor to present the SONSIK activities, challenges and opportunities in front of

the think tank of Nepal. I will try to cover objective, SONSIK previous leaders,

annual work plan and current done activities, introduction to our 15th EC and

advisory board, significance of division into four different region, photo gallery,

role of old and new students to SONSIK, and finally the challenge and

opportunities of SONSIK etc.

Key words: SONSIK, activities, challenges, opportunities

Super-Speed Tube Train System, Effect of external loads on its

performance and its Contribution for the Improvement of

Transportation System. 1Devkota Prakash., 2Joonam Park [email protected] Wonkwang University, South Korea

Air resistance is very important consideration for any kinds of vehicles that travels in high

speed. Vacuum tube transportation system, therefore, can be considered as one of the most

effective transportation system. In the system, high speed of the train can be achieved by

reducing the air pressure and maintaining the airtightness inside the tube. As the maintenance

of the low pressure inside the tube is crucial for the system, the impact of externally applied

loads on the air-tightness performance level should be taken into consideration. Therefore, this

study aimed at investigating the effect of load-induced cracks on the air-tightness of concrete

vacuum tube structures. A predictive model was developed to describe the air flow rate into

the concrete tube structures through cracks. The leakage rate of air due to the cracks was then

assessed through parametric analysis by varying the crack parameters, i.e., the width, length

and number of cracks. Among the three parameters, the crack width shows the greatest effect

on system airtightness. The degree of cracking in the tube structure was expressed by defining

the crack index and finally, the relationship between the crack behavior and its effect on the

air-tightness performance of vacuum tube structure is established.






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Possibilities of zebrafish as tools for drug discovery from medicinal

plants of Nepal. 1*Sushil Bhandari 1E-mail: [email protected], Wonkwang University School of Medicine, South

Korea.

Nepal is well known for its medicinal plants around the world. Nepalese medicinal plants are

very popular since the vedic period and are integral part of traditional medicine practice of

indigenous community of Nepal. They have also been used in many ayurvedic formulations.

However, the uncontrolled exploitative practices and lack of effective conservation have pushed

it to the stage of extinction. Scientific study of these valuable plants based on modern

technology, traditional knowledge and ethnomedicinal practices for drug discovery and its

commercialization to the world market can bring prosperity in the country. Zebrafish is a

tropical freshwater fish native to the himalayan region. It has been used as tools for drug

discovery in the developed country due to its advantages over other animal models in scientific

research. It has gained popularity in toxicity and pharmacological screening of chemical

compounds due to its advantages over other model organisms in screening test. But we have not

been able to utilize it at all. In Nepal, Zebrafish has high possibility in pharmacological

screening of bioactive compounds extracted from medicinal plants. So, it is of immense

importance to introduce zebrafish for scietific study of bioactive compounds derived from

medicinal plants and drug discovery from it for national prosperity.

Key Words: Zebrafish, Drug discovery, Medicinal Plants


Potential impact of climate change on the species richness of subalpine plant

species in the mountain national parks of South Korea Pradeep Adhikari*, Man-Seok Shin, Ja-Young Jeon, Hyun Woo Kim, Seungbum

Hong, Changwan Seo *[email protected], National Institution of Ecology, South Korea

Subalpine ecosystems at high altitudes and latitudes are particularly sensitive to climate change.

In South Korea, the prediction of the species richness of subalpine plant species under future

climate change is not well studied. Thus, this study aims to assess the potential impact of

climate change on species richness of subalpine plant species (14 species) in the 17 mountain

national parks (MNPs) of South Korea under climate change scenarios representative

concentration pathways (RCP) 4.5 and RCP 8.5 using maximum entropy (MaxEnt) and

Migclim for the years 2050 and 2070. Altogether, 723 species occurrence points of 14 species and six selected variables were used in

modeling. The models developed for all species showed excellent performance (AUC >0.89 and

TSS>0.70). The results predicted a significant loss of species richness in all MNPs. Under RCP

4.5, the range of reduction was predicted to be 15.38-94.02% by 2050 and 21.42-96.64% by

2070. Similarly, under RCP 8.5, it will decline 15.38-97.9% by 2050 and 23.07-100% by 2070.

The reduction was relatively high in the MNPs located in the central regions (Songnisan and

Gyeryongsan), eastern region (Juwangsan), and southern regions (Mudeungsan, Wolchulsan,

Hallasan, and Jirisan) compared to the northern and northeastern regions (Odaesan, Seoraksan,

Chiaksan, and Taebaeksan). This result indicates that the MNPs at low altitudes and latitudes have a large effect on the

climate change in subalpine plant species. This study suggested that subalpine species are

highly threatened due to climate change and that immediate actions are required to conserve

subalpine species and to minimize the effect of climate change.

Key words: Climate change, mountain national park, species distribution model, species

richness, subalpine species.


mailto:*[email protected]

August 2

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LOCAL ORGANIZING COMMITTEE SCIENTIFIC COMMITTEE

Local program Coordinator :

-Tonking Bastola, Wonkwang Uni.

Members:

Chair: Prof. Bhanu Shrestha,

Kwangwoon University

Dr. Taraman Kadayat DGMIF

Dr. Ramakanta lamichhane Wonkwang Uni.

Dr. Sushil Bhandari Wonkwang Uni.

Dr. Thakur Subedi Hannam Uni.

Dr. Ajay Kumar Jha Kyungpook Nat. Uni.

Dr. Ramesh Lama Chosun Uni.

Dr. Ekraj Baral Chonbuk Nat. Uni.

Dr. Suresh Poudel Chonnam Nat. Uni.

Dr. Balkrishna Ghimire Korea Nat. Uni.

Dr. Mahesh Bhatta Sungkyunkwan Uni.

Dr. Krishna P. Dhakal Sungkyunkwan Uni.

Dr. Jeeban Poudel Kongju NatUni.

Dr. Shivaram Bhandari Chonbuk Nat. Uni.

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-Prakash Raj Pandeya

-Acharya Shree Krishna

-Anjali Sharma

-Bhattarai Saurabh

-Dipendra Khadka

-Nisa Adhikary

-Ramesh Pariyar

-Prakash Devkota

-Raja Shrestha

-Rajmani Sigdel

-Saanvi Arpana

-Santosh lamichhane

-Shrestha Abin

-Subham Sharma

-Sundar Baruwal Chhetri

-Aashreeka Lama

-Sumeet Manandhar

15TH EXECUTIVE COMMITTEE

Organizing Committee

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Program Chair: Tulsi Poudel, President SONSIK

Coordinator: Prakash Devkota, Vice_President SONSIK

ADIVISORY BOARD 15TH EXECUTIVE COMMITTEE ADIVISORY BOARD

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NON-RESIDENT

NEPALI ASSOCIATION

-KOREA

WONKWANG UNIVERSITY NEPALESE CLUB

Society of Nepalese Students in Korea

(SONSIK)

Supporter:

Sponsor:

Media Partners:

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