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Transcript of Welcome to the CLU-IN Internet Seminar Superfund Research Program P42 RFA Briefing (RFA ES 14-007...
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Welcome to the CLU-IN Internet SeminarSuperfund Research Program P42 RFA Briefing(RFA ES 14-007 – rerelease of RFA ES 14-001)
Sponsored by: National Institute of Environmental Health Sciences,
Superfund Research Program
Presenters:William A. Suk, Director, Superfund Research Program (SRP), NIEHS ([email protected])
Heather Henry, Program Administrator, SRP NIEHS ([email protected]) Danielle Carlin, Program Administrator, SRP NIEHS ([email protected])
Lisa Edwards, Grants Management Specialist, NIEHS ([email protected])Michelle Victalino, Grants Management Specialist, NIEHS ([email protected])
Leroy Worth, Scientific Review Officer, NIEHS ([email protected])
Contributors:Michelle Heacock, Health Scientist, NIEHSBeth Anderson, Program Analyst, NIEHS
Link to RFA: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.htmlLink to RFA Information Page: http://
www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/rfa/index.cfm
June 27, 2014
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Today’s Focus: RFA Re-Release Updates
Notice to terminate RFA-ES-14-001: Posted
May 16, 2014
RFA Re-released as RFA-ES-14-007:
Posted June 12, 2014
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Funding Opportunity Webinar – P42 Center RFA - Rerelease
Agenda• Update of Changes in RFA (20 minutes)
– General and Training-specific: Dr. Danielle Carlin – Training Review Criteria and Budget: Dr. Heather Henry
• Question / Answer (30 minutes)
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RFA Re-Release – General Updates• Clarifications:
– “Relation to Overall Center" statement is in the Research Strategy section and is part of the 12 page limit for that section. The length of the statement is not specified in RFA-ES-14-007 (RFA-ES-14-001 specified 1 page limit).
– “Community Engagement Statement” goes in the Research Strategy for Community Engagement Cores and Community Engagement Research Projects.
– Travel to annual meeting – Admin Core Budget should include travel for Center Director, Center Administrator, Training Core leader, Research Translation Core leader, Community Engagement Core leader, and four trainees.
– Project Narrative for all projects and cores (except Training Core).
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RFA Re-Release – General Updates• Do not include “Table of All Personnel” in the Overall “Other
Attachments”. This was eliminated because ASSIST will automatically generate a list of all personnel.
• Table of Trainees is no longer a part of the Training Core “Other Attachments”. It is now called the “Trainee List” and must be included in the Training Core “Progress Report” section (for competitive renewal applications only).
• New Biographical Sketches: DOES NOT APPLY to this RFA; applies to all NIH grant applications planned for FY 2016 and beyond.
• NOT ES 14-009: Only one application per institute is allowable.
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Goals and purpose of Training Core remains unchanged• Training Core must follow Ruth L. Kirschstein National
Research Service Award (NRSA) Application Guidelines with modifications specified in the RFA.
• What’s New – Use (NRSA) ASSIST Application Component and Budget – Recruitment & Retention Plan to Enhance Diversity – Plan for Responsible Conduct of Research– Trainee List (required only for renewals)
• What’s Modified– Review criteria– Budget– Sections/Page Limits
RFA Re-Release – Training Updates
SRP Training Core ≠ NRSASRP TCs must adapt to NRSA Forms, but much of prior application’s text should be sufficient.
Training Core Function: Graduate and Post-doctoral level cross-disciplinary training
Training Core: Goals Unchanged
Cost Limitations:• New Applicants:
$100,000 Direct Costs• Renewal Applicants:
$125,000 Direct Costs
• Promote interactions between biomedical and environmental science/engineering trainees
• Professional development• Communicating research effectively• Involvement in Research Translation,
Community Engagement, etc.• Achieves program integration
Inquiring Reviewers want to know:• Recruitment?• Past trainee successes• Use of CareerTrac (for
renewals)
“Suggested Research and Activities” document http://www.niehs.nih.gov/research/supported/srp/funding/rfa.cfm)
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P42 Funding Opportunity Announcement
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Must Use “NRSA Training” component for the Training Core.
The Training Core is 25 pages (i.e., 25 pages include Background, Program Plan, and Recruitment and Retention Plan to Enhance Diversity).
NRSA Training Component - Information page
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Look for ‘NRSA Training’ in the
menu
Follow RFA-ES-14-007 instructions
(and SF424 instructions, where applicable) for each
‘Tab’
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See next slides with instructions for filling out these attachments
No Data Tables for this RFA.
Biosketches
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Training Core • Follow Section “8.7” in the SF424 (R&R) Supplemental Instructions for
Preparing Institutional Ruth L. Kirschstein National Research Service Award (NRSA):
• Introduction to Application: For Resubmission applications only.• Background
– Provide the rationale for the Training Core and the need for the cross-training proposed.
– Indicate how the Training Core will relate to current training activities at the applicant institution.
• Program Plan– Program Administration– Program Faculty– Proposed Training– Program Evaluation– Trainee Candidates– Institutional Environment and Commitment to the Program
Page Limit = 25Includes Background, Program Plan, and Recruitment and Retention Plan to Enhance Diversity (Attachments 2-4 of Research Training Program Plan form).
Note: NRSA Tables are not applicable to this FOA.
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Training - Program Plan
• Program Administration– Strengths of the Training Core Leader– Planned strategy and administrative structure to oversee and monitor
the core
• Program Faculty – Include information about Center faculty who will serve as
preceptors/mentors and provide guidance and expertise appropriate to the level of trainees proposed in the application.
– Describe the complementary expertise and experiences of the proposed Center Faculty.
– For any proposed Center Faculty lacking research training experience, describe a plan to ensure successful trainee guidance by these individuals.
– Describe the criteria used to appoint and remove Center Faculty and to evaluate their participation.
Note: Program Plan should be saved as a single file
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• Proposed Training– Overview of the Training Core – Objectives and activities – Training level and proposed number of trainees– Reflect the interdisciplinary nature of the Center
• Use of interdisciplinary approaches to training • Opportunities to develop the trainees’ current research/activities
to enhance their own professional career development and to receive training on best practices in Responsible Conduct of Research
• Reporting of information about the Center’s trainees to the SRP • Recruitment plan for all trainees (see also "Diversity Recruitment
and Retention Plan”)
Training - Program Plan (Cont’d)
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• Program Evaluation– Plan to review and determine the quality and effectiveness of the
Training Core – Include the utilization and frequency for trainee information
submission to NIH CareerTrac (https://careertrac.niehs.nih.gov/)– Metrics to be evaluated (e.g., Core activities completed, degree
completion, publications, fellowships/honors, and subsequent post-training positions)
– Feedback from current and former trainees to help identify weaknesses/strengths
• Trainee Candidates– Size and qualifications of the trainee candidate pool– Plan to recruit candidates and implementation (see also section on
Recruitment and Retention Plan to Enhance Diversity)
Training - Program Plan (Cont’d)
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• Institutional Environment and Commitment to the Program– Sponsoring institution must assure support for the proposed Training
Core (assurance that sufficient time will be allowed for the Training Core Leader and other Center Faculty to contribute to the proposed training)
– SRP Training Core is distinctive from existing Training Programs; indicate synergy between programs, if applicable
Training - Program Plan (Cont’d)
Timeline and Milestones: The Training Core description should indicate the frequency for trainee information submission/updates to the NIH CareerTrac database.
"Relation to Overall Center" statement within the Program Plan • State the relevance of the core to the goals of the overall Center, how this
core integrates with other projects and cores, and how the findings/activities of this core assist in solving the problem(s) that the Center is addressing.
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• Recruitment and Retention Plan to Enhance Diversity– Follow instructions as provided in Chapter 8 of the SF424 (R&R) Application
Guide – Include description of plans to recruit a diverse trainee pool and may wish to
include data in support of past accomplishments– Information should be included on both successful and unsuccessful
recruitment strategies (as applicable) – Note – this used to be a separate attachment in the Training Core.
• Plan for Instruction in the Responsible Conduct of Research – Follow instructions as provided in Chapter 8 of the SF424 (R&R) Application
Guide. General plan description is acceptable. Utilizing/referencing existing institutional training (including online) is acceptable.
Training Core
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Training Core - Renewals
• Progress Report (Renewal Applications Only):• As part of your progress report, provide a "Trainee List” (Note –
this used to be a separate attachment in the Training Core).• Identify the graduate students and post-doctoral researchers
who participated in the Training Core during the previous funding cycle. – Include the names of the trainees, their SRP Center-associated mentor
name, project/core. – All trainees should be entered into NIH CareerTrac database:
https://careertrac.niehs.nih.gov/.
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Example of a “Trainee List” found on “Tips for Applicants” webpage.http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/rfa_tips/index.cfm
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Training Core - Review Criteria• Training Program and Environment
– Objectives, design, and direction– Approaches and methods employed to develop the training curriculum and
reflect the interdisciplinary nature of Center– Institutional commitment
• Training Leadership PD(s)/PI(s) – Experience in development of training programs– Encouragement of trainees to participate in professional development
and/or leadership opportunities– Plan for communicating with SRP about training activities and trainees – For renewal applications, tracking of trainees (e.g. in CareerTrac) and their
accomplishments
Score based on review criteria below and its contribution to Overall SRP Center
Note: Individual criterion scores will not be provided (this is for all Cores)
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• Preceptors/Mentors – Project and Core Leaders as strong preceptors/mentors– Plans to ensure that preceptors lacking sufficient research training
experience will be successful mentors • Trainees
– Plans for recruitment of trainees – Research/activities supported by the Center listed within the Training
Core • Training Record
– Success of trainees in completing their research programs– Productivity: e.g. research accomplishments, publications, fellowship
or career development awards, achievement of career goals, scientific leadership positions, etc.
– Plan to assess the quality and effectiveness of the training
Training Core (Updated) - Review Criteria
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Training Core (Updated) - Review Criteria• Recruitment & Retention Plan to Enhance Diversity
– Evaluation of recruitment and retention plan to enhance diversity and strategies to enhance diversity
• Training in the Responsible Conduct of Research– Plan to fulfill NIH requirements for instruction in the Responsible
Conduct of Research (RCR) – Relation to the five instructional parts outlined in the NIH Policy on
Training in the RCR: format, subject matter, faculty participation, duration, and frequency
Additional Review Considerations • Reviewers will consider the following items, but will
not consider them in providing an overall impact/priority score
• Rated as Acceptable or Unacceptable
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Note: Recommend place trainees on project/core budgets
Part A: If trainee is covered by the training core:• Use the stipend category to request “salary”
for the trainees• Stipend expected to be consistent with
trainee salaries listed in Projects and Cores and NIH policy
• "Tuition/Fees" in should be consistent with trainee Tuition/Fees from Project and Core budgets.
Note: NRSA stipend levels do not apply to this FOA.
Note: The SRP mandates specify that training is graduate-level and is not intended for undergraduates.
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Part B: • Include expenses associated with the
training core (such as salary support for Training Core Leader and other staff, consultant costs, equipment, research supplies, staff travel, etc.) in the "Training Related Expenses."
F. Budget Justification• Indicate the total number of trainees
participating in the Training Core, including those whose salary/costs are being covered in their respective research projects/cores
• Provide details on level of effort and salary of core leader/staff, description other expenses, etc. in the justification section. Be sure to provide a breakdown of the Training Related Expenses.
Note: 8% NRSA indirect cost rates do not apply to this FOA.
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• All values on this form are calculated automatically
NRSA training budget will be rolled up into the Composite Budget and the Overall Budget summaries.
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Frequently Asked Questions and Tips
Frequently Asked Questions – posted on http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/
Application Tips: http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/rfa_tips/index.cfm
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More on ASSISTFollow all special instructions noted in Section IV. of the announcement.The eRA validations will catch many, but not all, submission requirements. FOA-specific requirements are not typically system-enforced. Applications that do not comply with the instructions may be delayed or not accepted for review.http://grants.nih.gov/grants/ElectronicReceipt/avoiding_errors.htm
• Will process application with wrong/expired RFA number – be sure to use: RFA-ES-14-007.
• Will NOT automatically roll your old application into the new RFA. You must reload the entire application.
• Will allow you to add attachments that are not allowed/required. Any additional/extra attachments not required in the RFA may cause your application to be rejected by CSR or NIEHS.
• Take Home Message – please submit at least a week before due date and make sure everything is there that should be (and nothing more).
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Resources• RFA Webpage: http
://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/
• SF424 (R&R) Application and Electronic Submission Information” webpage:– http://grants.nih.gov/grants/funding/424/index.htm
• Applying Electronically to Multi-project Applications:– http://grants.nih.gov/grants/ElectronicReceipt/com_index.htm
• Need help with ASSIST?– http://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#about
eRA Commons - https://commons.era.nih.gov/commons/index.jsp Registered PD/PIs can check assignment/contact information, review outcome, and other important information.
eRA Commons Help Desk:Hours: Mon-Fri, 7AM-8PM EDT/EST Web: http://era.nih.gov/help/ Toll-free: 866-504-9552. Phone: 301-402-7469. TTY: 301-451-5939.
PLEASE PRINT THIS AND KEEP A COPY HANDY!!!!!
NIEHS Contacts:Program: William A. Suk [email protected], (919) 541-0797Heather Henry [email protected], (919) 541-5330Danielle Carlin [email protected], (919) 541-1409
Grants Management: Lisa Edwards, [email protected], (919) 541-0751 Michelle Victalino, [email protected], (919) 316-4666
Scientific Review:Leroy Worth, [email protected], (919) 541-0670
P42 Multi-Project Centers
Acknowledgements:EPA’s CLU-In.org
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Thank You!
QUESTIONS??
Webinar Gurus Jean Balent, EPA TIFSDJustin Crane, MDB, Inc.Kevin O’Donovan
SRP TeamBill Suk, DirectorDanielle CarlinHeather HenryBeth AndersonMichelle HeacockRosemary Moody
SRP TeamBill Suk, DirectorDanielle CarlinHeather HenryBeth AndersonMichelle HeacockRosemary Moody
NIEHS StaffLeroy Worth, SROAlfonso Latoni, Review ChiefLisa Archer Edwards, GMOMichelle Victalino, GMSGwen Collman, DERT Director
Questions not covered during seminar will be answered off-line ASAP and posted on P42 Funding Opportunity Webpages.
Audio Archive will be available in approximately 2 weeks and are accessible from the above website.
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Slides from January 2014 Webinar
Updates indicated in RED TEXT
SRP Funding Mechanisms Multi-Project Centers (P42)Designed for integration across disciplines: Biomedical and Non-Biomedical Research; Community Engagement, Research Translation, and Training. Basic and application-oriented.Request for Applications. Annual RFA.
Multi-Project Centers (P42)Designed for integration across disciplines: Biomedical and Non-Biomedical Research; Community Engagement, Research Translation, and Training. Basic and application-oriented.Request for Applications. Annual RFA.
Individual Research Project (R01)Designed to address specific issues to complement the multi-project research program; tackle issues of emerging concern for Superfund. Closed.
Individual Research Project (R01)Designed to address specific issues to complement the multi-project research program; tackle issues of emerging concern for Superfund. Closed.
Small Business Research Grants SBIR/STTR (R41-44)Foster the commercialization of technologies, relevant to hazardous substance clean-up and monitoring. Ongoing Funding Opportunity
Small Business Research Grants SBIR/STTR (R41-44)Foster the commercialization of technologies, relevant to hazardous substance clean-up and monitoring. Ongoing Funding Opportunity
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Conference Grants (R13)Provides funding for conferences related to SRP mandates. Ongoing Funding Opportunity
Funding Opportunities: http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/index.cfm
Occupational Training (R25)Emerging issues in EHS training. Closed.
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SRP Mandates under SARA
Development of:
• Advanced techniques for the detection, assessment, and evaluation of the human health effects of hazardous substances
• Methods to assess the risks to human health presented by hazardous substances
• Methods and technologies to detect hazardous substances in the environment
• Basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances
University-based basic research program established in 1986 under Superfund Amendments Reauthorization Act (SARA)
Health Effects
Assessing Risks
Detection
Remediation
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SRP Strategic Plan (2010)• Relevance
– Interaction with stakeholders– Problem-based, solution-oriented research– Critical research areas
• Impact• Innovation
http://www.niehs.nih.gov/research/supported/assets/docs/r_s/srp_about_2010_plan.pdf
SRP Stakeholders
Sister Superfund Programs:• US Environmental Protection Agency (EPA)• Agency for Toxic Substances and Disease Registry (ATSDR)
Others: federal agencies, state, local, and tribal entities responsible for sites; individuals and communities living near hazardous waste sites
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RFA-ES-14-007SUPERFUND HAZARDOUS SUBSTANCE RESEARCH AND TRAINING PROGRAM (P42)
Improve public health by supporting integrative, inter-disciplinary research.
Provide sound science, data, information, and knowledge to inform the risk assessment and remediation management processes for hazardous waste sites.
P42 Multi-Project Centers
Bring expertise of multiple biomedical and environmental science disciplines to address scientific uncertainties facing the National Superfund Program.
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Community Engagement
Research Translation Problem
Solution
Environmental Science and Engineering
Biomedical Science
P42 Multi-Project Centers
Superfund Stakeholders Stakeholder Communities
Research and Training
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P42 Multi-Project CentersScope of Research
SRP Mandates• Advanced techniques for the detection, assessment, and evaluation of the effect of hazardous substances on human health• Methods to assess the risks to human health presented by hazardous substances• Methods and technologies to detect hazardous substances in the environment• Basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances
Strategic PlanRelevance: to SuperfundImpact: to StakeholdersInnovation: Trans-disciplinary/Paradigm-shifting
Programmatic Balance(See Current Grantees: http://tools.niehs.nih.gov/srp/programs/index267.cfm)
Broad Scope – Ultimately should be a clear link to Superfund.
Suggested Research Topics: High priority areas for EPA/ATSDR colleagues
Not Required: Superfund Site; CERCLA Substance
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Community Engagement Core
Administrative Core
Research Translation Core
Biomedical(≥ 2 Projects)
Environmental Science and Engineering
(≥ 2 Projects)
Training Core
Research Support Core(s) optional
P42 Multi-Project CentersAll Components Interacting, Addressing Problem
New Proposals: up to $1.6M/year direct costs for 4 yearsRenewal Proposals: up to $2.0M/year direct costs for 5 years
Total: 8 - 12 Components
Health Effects
Epidemiology
Mechanistic Toxicology
Fate and Transport
Hydrogeology
Remediation Engineering
Biomedical(≥ 2 Projects)
Environmental Scienceand Engineering
(≥ 2 Projects)
P42: Projects
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• Each project is stand-alone• independent testable hypothesis• logical progression of tasks
• Basic to application - oriented• Integration with other projects
• Research Aims• Sharing: data, specimens, technology
• Interaction with Cores• Training, Community
Engagement• Research Translation
(including investigator-initiated research translation)
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P42: Projects
Interactions:Cross-reference interactions between projects and cores. Should be consistent throughout.
Abstract / Titles – Avoid Jargon• P42 Reviewers have broad expertise• Write abstracts/titles for a general audience• Write Specific Aims for technical experts• http://grants.nih.gov/grants/plain_language.htm
FOCUS!!!!Centers should be VERY judicious in assembling research projects. Center should, with projects, keep a clear focus and not try to do too much!!
Include projects with most solid connection to the Center’s problem-solving theme.
Lean Times: Not too big! Come in under budget, well under 12-component limit. Especially True for New
Center Proposals!
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http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/index.cfm
P42: Projects
NEW: for investigators to explore opportunities for sharing research products and broad opportunities for research translation during project development. 1 paragraph PLAN for each:
Resource Sharing Plans
Research Data Sharing Plan:• Publication-based data-sharing
opportunities; databases• Explain if sharing not appropriate.Must follow all NIH required data-sharing.
See “Suggested Research and Activities” for Investigator-Initiated Research Translation suggestions.
Investigator-Initiated Research Translation Plan: Identify potential interactions between researcher and end-user (not researcher to researcher) drawing from SRP’s 4 research translation components. (Consistency with RTC).
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P42: Administrative Core (Required)
Administrative Core (AC) Functions– Planning and coordination– Promote cross-discipline interaction– Ensure research translation– Oversee fiscal and quality management
External Advisory Committee (EAC)– Provides Guidance to Director
– Scientific Merit– Relevance, Integration – Research Translation, Community
Engagement, Training activities
Anticipated EAC Members*Academics (biomedical AND environmental science
and engineering), Stakeholders, EPA/ATSDR, Industry, Community
*New Applicants: include expertise of potential EAC members, not names
Not to exceed $125,000 Direct Costs
AC Breaks Silos• Between Disciplines• Basic to Applied• Lab to End-user
AC Promotes CareersTrainees, Early Stage Investigators,Succession Planning (if applicable)
Research Translation Core (Required)Research Translation Core Function:Communicating and facilitating the use of research findings emanating from the Center in the manner most appropriate for their application and the advancement of research objectives.
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Include Plan for Four Components1. Communication2. Government Partnerships3. Technology Transfer4. Information Dissemination
Note: SRP Research Translation – much broader scope than
NIH’s Clinical Translation (bench to bedside).
Not to exceed $125,000 Direct Costs
Information from Center to Center as well as Center
outward (to all end-users)
Plan for Reporting News to SRP: • For Example: reporting to the SRP
Data Collection Form: http://tools.niehs.nih.gov/srp/resources/rtc.cfm
See Suggested Research and Activities Document for ideas for the RTCs:http://www.niehs.nih.gov/research/supported/dert/programs/srp/funding/rfa/index.cfm
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2. Partnerships with Government Agencies
Research Translation Core (RTC)
4. Information Dissemination to Other End-Users
End-Users: formal/informal education groups, hazardous waste practitioners, lay public, other academic researchers
Examples: Educational materials, Web sites, webinars, “outreach,” etc.
Where to start?• SRP’s Additional Resources Webpage* • Find your EPA Region’s Superfund
Technical Liaison / ATSDR staff• Superfund Site Remedial Project Manager
1. Communicating within SRPa. Project-Specific: Within Centerb. Center-Specific: Center Outc. Between Center/SRPd. Between Centers
EPA/ATSDR a priority, but not a requirement.
Expertise: staff with experience in diverse science topics.
RTC – work with investigators on research translation plan for each project (clusters of projects).
* http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm
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Community Engagement Core Function: To enhance knowledge exchange and to support community needs with regard to
the science emanating from the Center
Community Engagement Core (Required)
Target communitiesSRP defines target communities as those impacted by sites contaminated with hazardous substances.• Members of the affected community• May also include: local government,
tribal councils, community service groups, non-governmental organizations Not to exceed
$100,000 Direct Costs
A Community Engagement Component Statement must be included in application.
HIGHLIGHT “Bidirectionality” between community and Center (not “outreach”)
Where to start?• SRP Additional Resources Webpage*• Suggested Research and Activities
Document• Develop logic model
* http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm
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Theme of Center
Impacted Community
BIDIRECTIONAL
Research Products
Appropriate Application
ITERATIVE
End-users
Research Translation
• Initiated by the Center (RTC/Investigator)
• Based on research “product”• Opportunistic and Rapid Response• Critical role reporting successes
• Partnership-driven• Finite/Defined Activities
• Provide access to expertise or conduct community-based projects
Community EngagementShared Challenge: Finding the most Appropriate End-User /
Community Group for Center Research and Activities
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Training Core Function: Graduate and Post-doctoral level cross-disciplinary training
Training Core (Required)
Cost Limitations:• New Applicants:
$100,000 Direct Costs• Renewal Applicants:
$125,000 Direct Costs
• Promote interactions between biomedical and environmental science trainees
• Professional development• Communicating research effectively• Involvement in Research
Translation, Community Engagement, etc.
• Achieves program integration
Inquiring Reviewers want to know:• Recruitment?• Past trainee successes• Use of CareerTrac (for
renewals)
Please refer to Training Core
Changes section of webinar for Format
Changes in ES-14-007
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• Research Support Core – Provides centralized services– Shared by at least 2 projects
P42: Research Support Core (Optional)
• Pros and Cons of RSC – Pros:
– Excellent Interactions/Integration– Opportunities for Training– Assurance of Quality
– Cons: – May not be critical (if facilities already available)– 12 component limit
If Research Support Core is not included, project should adequately detail research support activities (e.g. QA/QC)
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Cost Limitations (Direct)
Core Limitations (Direct):• Administrative - $125K• Research Translation - $125K• Community Engagement - $100K • Training Cores
– New applicants: $100K– Renewal applicants: $125K
Cores Sum ≤ 20% Total Center Administrative
Research TranslationCommunity Engagement
Training
Center: New Applicants: up to $1.6M/year direct costs for 4 yearsRenewal Applicants: up to $2.0M/year direct costs for 5 years
Renewal Applicants: ≤ $400K
20%AC, RTC, CEC, TC
80%Research Projects, Research Support Cores
New Applicants: ≤ $320K
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• Budget Ceilings for Overall Center and Cores• Total Projects and Cores limited to 12
Components• Training Cores required• Research Support Cores optional• Environmental Science and Engineering
replaced “Environmental Science” and “Non-biomedical”
Recent Changes
Resource Sharing Plan for Projects
Review Criteria Changes• Modifications to overall center description of Significance,
Investigator, Innovation, Approach and Environment• Cores: each core has specific review criteria
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Recent Changes
• Research Translation Core– Translation plan for each project
• Research Strategy (12 page limit)• Review Scoring System• One Resubmission (A1)• Community Engagement
– Core is Required– Community Engagement Projects (CEPs)
• explicitly mentioned (had always been welcome)• e.g. community-based participatory research (biomedical and
environmental science)
– New: “Community Engagement Component Statement” section for CEC and CEPs.
Unchanged Characteristics• Not a site-specific program• Basic to application-oriented research• Innovative approaches to research
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Community Engagement
Research Translation Problem
Solution
Non-Biomedical Approaches
Biomedical Approaches
A Successful P42 Center
Superfund Stakeholders Stakeholder Communities
Research and Training
* Addressing Important Problem
* Projects and Cores Uniformly Meritorious
* Integration, Interaction, Synergy:- Biomedical and Environmental Science &
Engineering- Projects and Cores
* Aids Stakeholders in Effective Decision-Making
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NIEHS SCIENTIFIC PEER REVIEW
LEROY WORTH, PHD (2014 P42 REVIEW )
Review
Non-responsive(return to applicant)
Responsive
Review Committee
Discussed
Funding decisionsand awards
(June/July 2015)
SummaryStatements
Letters of Intent(August 3, 2014)
NAEHS Council(May 2015)
SummaryStatements
Not - Discussed
The Peer Review Process
Administrative Review
Peer Review Meeting (Winter 2015)
Receive Applications(September 3, 2014)
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• Submission of Letter of Intent (LOI):– Assists in review planning – Email to Dr. Leroy Worth at [email protected] Requested by
August 3, 2014 (not required, but highly recommended)
• Include in the LOI:– Descriptive title of the Overall Center
• Brief description of the research proposed in the Center• Include the title of each Research Project and Core
– Name, address, and telephone number of the PD(s)/PI(s)– Names of key personnel (Project and Core Leaders)– Names of any participating institutions
Pre-Submission of P42 Application
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P42 Peer Review Process• Review Criteria are in the solicitation: http://
grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html • Review of the Individual Research Projects, Cores• Review the Overall Center
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Research Projects
• Significance• Investigator(s)• Innovation• Approach• Environment
• Contribution to SRP Center• Other Specific Criteria*
NIH’s Five Review Criteria(criterion
scores 10-90)
Impact Score(10-90)
Each Project reviewed. Each Receive Criterion Scores and written critiques. Note-Applications not discussed will not be provided an overall impact score (e.g Center , individual Projects, and Cores).
Note: Human Subjects, Animal Care, and Biohazards can be considered in the overall score. Budget Concerns are not considered in score.
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Cores
• Contribution to SRP Center• Other Criteria Specific to Each Core
– Administrative– Research Translation Core– Community Engagement– Training (NOTE – see previous slides for
review criteria changes from ES 14-001)– Research Support Cores(see RFA for specific criteria)
Impact Score(10-90)
Overall Center
Final Score (Range: 10-90)
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Addresses a critical problem relevant to the SRP
Relevance/Merit of Projects and Cores (scientific gain) Collaboration/Integration/Synergy
Leadership
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Helpful Hints
• Read and understand the Funding Announcement• Contact Program Staff for clarification of scientific matters
and Grants Management Staff for budget issues.• Follow the guidelines: page limits, font size, etc. • Start early………because:
Any mistakes made with electronic submission (i.e., ASSIST) may cause your application to be returned without further deliberation by NIEHS Review staff.
Grantsmanship Issues
• Be clear and concise….don’t expect reviewers to “know what you mean.”
• All the components are important. One weak research project will impact the overall score. Extraneous or unnecessary cores will reduce cohesiveness of the center.
• Too many projects…application sinks under its own weight.
• Inadequate time allowed to prepare application.
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NIEHS GRANTS MANAGEMENT
LISA EDWARDS, MBA
Budget
Electronic Budget
• Webinar for Applicants: Initial Look at the Electronic Submission Process of Multi-Project Applications
http://grants.nih.gov/grants/webinar_docs/webinar_20121213.htm
• SF424 (R&R) Detailed Budget forms differ from Paper PHS398 Budget Forms in both look/feel and substanceo Some items in different placeso Some items not collected as specific line items
• Budget data collected at component and subaward levels onlyComponent and subaward budget data used to auto-calculate “Cumulative” (Composite) budget
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Budget Preparation
*Just in Time: Request for information required prior to award.
Form Pages, Approvals, Other Support, Notices
Forms (http://grants.nih.gov/grants/forms.htm) SF424 (R&R) electronic submission
ApprovalsIACUC Approval (Vertebrate Animals)IRB Approval (Human Subjects)Begin process at time of application, but final approval will be requested for Just In Time*
Other Support“0%”, “Varies”, “As Needed”, etc., are not acceptableTotal time commitment cannot exceed 12 calendar months
New Notices• Revised Grants Policy Statement: NOT-OD-12-157
• Salary caps: NOT-OD-12-035http://grants1.nih.gov/grants/policy/salcap_summary.htm.
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Travel to Annual Meeting
Administrative Core Budget: Funds for travel by appropriate staff (i.e., Center Director, Project/Core Leaders, Center Administrator, and four trainees) to attend the Superfund Research Program three-day annual meeting shall be included in the Administrative Core’s budget for each year.
EscalationBudgets submitted in subsequent years may request an escalation on recurring direct costs. (Note: Currently NIH does provide an escalation in subsequent years)
Must be justified:• Is the amount of escalation requested supported by institutional policies? • Is the amount clearly stated?
Budget PreparationNon-Modular
Provide detailed categorical budgets• Each Project• Each Core• Each Subaward/Consortium (Note: SF424 will not allow Subawards on Subawards)• For Training Budget Pages – NRSA Budget forms must be used. Please see previous slideset.
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Budget Preparation• Parent Grant Direct Costs
– Consideration of equipment in the out-years will be based upon justification and availability of funds
• Subawards/Consortium– must follow same guidelines as parent; budget pages required and should
follow associated project or core– Subawards/consortium direct costs are included in the parent grant Subtotal
Direct Costs, which may be subject to budget caps– F&A of subawards/consortium is included in Total direct Costs of parent grant ,
but will not count against budget cap
• Budget Justifications (Be detailed and specific)• Are all costs itemized?• Are all additions and changes in subsequent/future years fully justified
and identified clearly; specifically changes in personnel effort?• For Training Budget Justification – Please see previous slideset for additional
details.
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R&R Budget Sections A & B
Personnel separated into 2 sections:• A. Senior/Key Person
o First field must be completed, even if person on a component given role of “Project Leader” and not PD/PI
• B. Other Personnelo Postdocs, Grad Students, Undergrads: Only number of personnel
required (not specific names)
*Include only personnel employed by (e.g., receiving salary from) your organization.
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R&R Budget
Sections C - E
Itemize up to 100 pieces of equipment. If more, include total dollars in line 11 and provide details in the Additional Equipment attachment
Not required for P42
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R&R Budget Sections C - E• Item D, Travel
o 424 form differentiates between foreign and domestic travel
o Continues to be treated as single cost (regardless of type) similar to 398 budget
• Item E, Participant/Trainee Support Costs o Do not use for NIH FOAs o Costs for NRSA Training-type components should use
Training Budget form
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R&R BudgetSections F - K
Subaward/Consortium/Contractual Cost not pre-populated. Include both Total Direct and Indirect cost
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R&R Budget Sections F-K• Tuition remission
o Include in Item F, Other Direct Costs (boxes 8, 9 or 10) • Supplies
o Not a major line item on 424 budgetso Included as line F.1 (Other Direct Costs: Materials and Supplies)
• Alteration and Renovationso Not a major line item on 424 budgetso Included as line F.7 (Other Direct Costs: Alterations and Renovations)
• Inpatient and Outpatient Care Costso 424 does not include as major / minor line itemo Current instructions require inserting in fields F.8-F.10 (Other Direct
Costs: Other Costs)
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P42 Multi-Project Centers• Announcement:
– RFA-ES-14-007: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-14-007.html
• Applications Details– One application per institution– Letters of Intent: August 3, 2014 March 10, 2014 – Due Date: Sept 3, 2014 April 10, 2014 by 5:00 PM local time of applicant
organization.– Scientific Review: Jan/Feb 2015 October, 2014– Awards Start Date: June/July 2015 April, 2015
• Consultation with SRP Program Administrator Staff is highly recommended (in person or teleconference)
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P42 Resources• RFA Webpage
– Suggested Research and Activities - Numerous areas of general interest as well as specific needs identified by stakeholders.
– Tips for Applicants – electronic submission, what to include, etc. – Additional Resources – Links to EPA, ATSDR, information to aid in
community engagement activities, and other helpful websites . – Program Contacts
Also see “Current P42 Grantees:” http://tools.niehs.nih.gov/srp/programs/index267.cfm
RFA Webpage: http://www.niehs.nih.gov/research/supported/srp/funding/rfa/index.cfm
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SRP PROGRAM ADMINISTRATOR
DANIELLE CARLIN, PHD, DABT
Electronic Submission:Using ASSIST
Note – There is additional information about ASSIST in the previous slides set.
What is ASSIST?
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ASSIST - Application Submission System & Interface for Submission Tracking
• Web-based system for the preparation and submission of multi-project applications
• ASSIST replaces Grants.gov• Grants.gov for single-project applications• ASSIST for multi-project applications
ASSIST allows applicants to…
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• Use existing eRA Commons and Grants.gov accounts
• Pre-populate data from eRA Commons profiles• Control application access• Have multiple users within and outside the
applicant organization work concurrently• Check application against Grants.gov and NIH
business rules before submitting• Preview/print NIH application image before
submitting• Track Grants.gov and eRA Commons submission
status
P42 Funding Opportunity Announcement
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Announcement text indicates electronic
submission is required.
Apply for Grant Electronically button brings applicant to the
ASSIST site.
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P42 Funding Opportunity Announcement
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Types of components allowed for the FOA and available in ASSIST for application preparation.
The Research Strategy page limits enforced in
ASSIST for each component.
Applicants will rely on the SF424 (R&R) Application Guide and the FOA text, especially Section IV. Application and Submission Information, when preparing their applications in ASSIST.
ASSIST Login
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https://public.era.nih.gov/assist
ASSIST leverages the eRA Commons accounts that most applicants already
have.
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Overall Component
The Overall Component is added to the component navigation.
The required forms are presented for the
component.
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Adding Additional Components
Click Add New Component to continue building your application.
Select from the drop-down list of
component types available for the FOA.
Adding Components
Applicants continue adding components to build out their application.
Components are grouped by Component Type.
Each component is given a random 3-digit, system-generated number for identification during application
preparation. Components will be given sequential numbers in the assembled application image.
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Projects & Cores – Additional Information
• Projects • Research Strategy: Each project should also include a "Relation
to Overall Center" statement.
• Administrative, Research Translation, Community Engagement, and Training Cores (Research Support Cores are optional)
• Research Strategy: each core will have a "Relation to Overall Center" statement; For CEC, include Community Engagement Statement in Research Strategy
• Other Attachments: Training Core will also have Diversity Recruitment and Retention Plan; Trainee List (required only for renewals)
• Other Attachments: Research Support Cores will also have Quality Assurance Statement
Refer to previous slides for instructions on using NRSA ASSIST Pages as well as additional attachment tables.
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Resources• SF424 (R&R) Application and Electronic Submission Information”
webpage:– http://grants.nih.gov/grants/funding/424/index.htm
• Applying Electronically to Multi-project Applications:– http://grants.nih.gov/grants/ElectronicReceipt/com_index.htm
• Need help with ASSIST?– http://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#about
eRA Commons - https://commons.era.nih.gov/commons/index.jsp Registered PD/PIs can check assignment/contact information, review outcome, and other important information.
eRA Commons Help Desk:Hours: Mon-Fri, 7AM-8PM EDT/EST Web: http://era.nih.gov/help/ Toll-free: 866-504-9552. Phone: 301-402-7469. TTY: 301-451-5939.
NIEHS Contacts:Program: William A. Suk [email protected], (919) 541-0797Heather Henry [email protected], (919) 541-5330Danielle Carlin [email protected], (919) 541-1409
Grants Management: Lisa Edwards, [email protected], (919) 541-0751 Michelle Victalino, [email protected], (919) 316-4666
Scientific Review:Leroy Worth, [email protected], (919) 541-0670
P42 Multi-Project Centers
Acknowledgements:EPA’s CLU-In.org
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Thank You!
QUESTIONS??
Webinar Gurus Jean Balent, EPA TIFSDJustin Crane, MDB, Inc.
SRP TeamBill Suk, DirectorHeather HenryBeth AndersonDanielle CarlinMichelle HeacockRosemary Moody
SRP TeamBill Suk, DirectorHeather HenryBeth AndersonDanielle CarlinMichelle HeacockRosemary Moody
NIEHS StaffLeroy Worth, SROLisa Archer Edwards, GMOMichelle Victalino, GMS
Questions not covered during seminar will be answered off-line ASAP and posted on P42 Funding Opportunity Webpages:• On SRP Website: http://www.niehs.nih.gov/research/supported/dert/cris/programs/srp/funding/rfa/index.cfm
Audio Archive will be available in approximately 4 weeks and are accessible from the above website.